Filtry
wszystkich: 586
-
Katalog
Wyniki wyszukiwania dla: CHAPERONE-USHER
-
Analysis of Reconstituted Tripartite Complex Supports Avidity-based Recruitment of Hsp70 by Substrate Bound J-domain Protein
PublikacjaHsp70 are ubiquitous, versatile molecular chaperones that cyclically interact with substrate protein(s). The initial step requires synergistic interaction of a substrate and a J-domain protein (JDP) cochaperone, via its J-domain, with Hsp70 to stimulate hydrolysis of its bound ATP. This hydrolysis drives conformational changes in Hsp70 that stabilize substrate binding. However, because of the transient nature of substrate and JDP...
-
Industrial User Interfaces
Kursy Online -
Australasian User Interface Conference
Konferencje -
Budget revenues from selected taxes in 2010-2019
Dane BadawczeThe state is not only a user of the country's resources, a buyer and seller of goods and services, but also under duress takes part of the money from its citizens or entities that carry out activities in the form of taxes. The source of the majority of budget revenues are taxes. The following dataset contains the budget revenues from selected taxes...
-
International Conference on Intelligent User Interfaces
Konferencje -
ACM SIGUCCS Conference on User Services
Konferencje -
IEEE Symposium on 3D User Interfaces
Konferencje -
Agnieszka Landowska dr hab. inż.
OsobyUkończyła studia na dwóch kierunkach: Finanse i bankowość na Uniwersytecie Gdańskim oraz Informatyka na WETI Politechniki Gdańskiej. Od 2000 roku jest związana z Politechniką Gdańską. W 2006 roku uzyskała stopień doktora w dziedzinie nauk technicznych, a w roku 2019 stopień doktora habilitowanego. Aktualnie jej praca naukowa dotyczy zagadnień interakcji człowiek-komputer oraz informatyki afektywnej (ang. affective computing), która...
-
FUNKCJONALIZOWANIE 2H-TIAZOLO[3,2-α]PIRYDYN-5-(3H)-ONÓW, ALTERNATYWNA ŚCIEŻKA SYNTEZY NOWYCH PILICYDÓW
PublikacjaUropatogenne szczepy Escherichia coli są przyczyną blisko 80% przypadków zakażeń dróg moczowych (ang. UTI- Urinary tract infection). Ponadto, aż 30% odmiedniczkowego zapalenia nerek występującego u ciężarnych kobiet jest spowodowane przez szczepy E.coli Dr+. Szerząca się lekooporność bakterii i trudności w leczeniu UTI wymusiły na środowiskach naukowych poszukiwania nowych związków chemicznych pełniących rolę chemoterapeutyków. Na...
-
Using Evidence-based Arguments to Support Dependability Assurance-Experiences and Challenges
PublikacjaThe article introduces to the problem of evidence-based arguments and their applications. Then, based on the experiences collected during commercial deployment of a concrete solution to this problem (system NOR-STA) we overview selected challenges and the ways of addressing them
-
Two bacterial small heat shock proteins, IbpA and IbpB, form a functional heterodimer
PublikacjaSmall heat shock proteins (sHsps) are a conserved class of ATP-independent chaperones which in stress conditions bind to unfolded protein substrates and prevent their irreversible aggregation. Substrates trapped in sHsps-containing aggregates are efficiently refolded into native structures by ATP-dependent Hsp70 and Hsp100 chaperones. Most γ-proteobacteria possess a single sHsp (IbpA), while in a subset of Enterobacterales, as...
-
ACM Symposium on User Interface Software and Technology
Konferencje -
Marcin Sikorski prof. dr hab. inż.
OsobyMarcin Sikorski jest profesorem w Katedrze Informatyki w Zarządzaniu na Wydziale Zarządzania i Ekonomii Politechniki Gdańskiej. Wcześniej odbył liczne pobyty w instytucjach naukowych, m.in. w Niemczech (Uniwersytety w Bonn i w Heidelbergu), Szwajcarii (ETH Zurich), Holandii (TU Eindhoven) i USA (Harvard University). Prof. Sikorski jest przedstawicielem Polski w komitecie TC13 Human-Computer-Interaction w międzynarodowej organizacji...
-
Natalia Sokół dr inż.
OsobyBACKGROUND Master of Science in Light and Lighting (2008-2009/11) The UCL Bartlett School of Graduate Studies, Faculty of the Built Environment, London, UK, www.bartlett.ucl.ac.uk MA Degree in Interior Architecture (1999-2004), The Academy of Fine Arts, Poznan, Poland, www.uap.edu.pl MA Degree in Art Education (1997-2002), Academy of Fine Arts, Poznan, Poland, www.uap.edu.pl MAIN RESEARCH AREAS · ...
-
Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor
PublikacjaIn 2009 Candida auris was first isolated as fungal pathogen of human disease from ear canal of a patient in Japan. In less than a decade, this pathogen has rapidly spread around the world and has now become a major health challenge that is of particular concern because many strains are resistant to multiple class of antifungal drugs. The lack of available antifungals and rapid increase of this fungal pathogen provides an incentive...
-
The noncanonical disulfide bond as the important stabilizing element of the immunoglobulin fold of the Dr fimbrial DraE subunit
PublikacjaAdhezyny fimbrialne bakterii patogennych stanowią liniowe asocjaty białkowe odpowiedzialne za wiązanie do specyficznych receptorów na powierzchni komórek gospodarza. Biogeneza tych struktur odbywa się przez system sekrecji typu chaperone/usher zakonserwowany pośród bakterii Gram-ujemnych. Powyższe struktury adhezyjne charakteryzują się wysoką odpornością na denaturację i deasocjację, powodowane przez temperaturę lub chemiczne czynniki...
-
Agnieszka Witkowska dr hab. inż.
Osoby -
International Conference on User Modelling, Adaptation, and Personalization (was AH and UM)
Konferencje -
Multiuser Stereoscopic Projection Techniques for CAVE-Type Virtual Reality Systems
PublikacjaDespite the development of increasingly popular head mounted displays, CAVE-type systems may still be considered one of the most immersive virtual reality systems with many advantages. However, a serious limitation of most CAVE-type systems is the generation of a three-dimensional (3-D) image from the perspective of only one person. This problem is significant because in some applications, the participants must cooperate with each...
-
Wojciech Wojnowski dr inż.
OsobyUkończył V Liceum Ogólnokształcące w Gdańsku w klasie o profilu matematyczno-fizycznym z wykładowym językiem angielskim. W 2009 roku rozpoczął studia na Wydziale Chemicznym PG na kierunku technologia chemiczna, uzyskując w 2012 roku tytuł inżyniera, a w 2013 tytuł magistra. W latach 2013–2015 studiował sinologię na Uniwersytecie w Nankinie dzięki uzyskaniu Stypendium Rządu ChRL. Po powrocie do Polski w 2015 roku rozpoczął studia...
-
Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide
PublikacjaDsb proteins control the formation and rearrangement of disulfide bonds during the folding of secreted and membrane proteins in bacteria. DsbG, a member of this family, has disulfide bond isomerase and chaperone activity. Here, we present two crystal structures of DsbG at 1.7- and 2.0-Angstrom resolution that are meant to represent the reduced and oxidized forms, respectively. The oxidized structure, however, reveals a mixture...
-
Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding
PublikacjaWe have reported that the hsp70 chaperone DnaK from Escherichia coli might assist protein folding by catalyzing the cis/trans isomerization of secondary amide peptide bonds in unfolded or partially folded proteins. In this study a series of fatty acylated benzamido inhibitors of the cis/trans isomerase activity of DnaK was developed and tested for antibacterial effects in E. coli MC4100 cells. Nα-[Tetradecanoyl-(4-aminomethylbenzoyl)]-l-asparagine...
-
Urszula Szybowska mgr
OsobyBibliotekarka i anglistka. Zawodowo zajmuje się rozwijaniem działań w zakresie obsługi i kształcenia polskich i zagranicznych użytkowników Biblioteki PG oraz w zakresie rozwoju i promowania projektów mobilnościowych w ramach programu Erasmus+. W latach 2017-2020 koordynator ds. współpracy międzynarodowej w Bibliotece PG ; od roku 2020 koordynator ds. programu Erasmus+ w Bibliotece PG ; 2018-2023 bibliotekarz ds. mediów społecznościowych...
-
Igor Garnik dr inż.
OsobyJest absolwentem Wydziału Elektroniki Politechniki Gdańskiej (1992). Z Politechniką Gdańską związany zawodowo od 1997 roku – zatrudniony najpierw jako asystent w Zakładzie Ergonomii i Eksploatacji Systemów Technicznych na Wydziale Zarządzania i Ekonomii, a następnie – po uzyskaniu stopnia doktora w 2006 roku jako adiunkt. W latach 2009–2015 pełnił funkcję koordynatora Bałtyckiego Festiwalu Nauki na Wydziale Zarządzania i Ekonomii....
-
Przemysław Kowal dr inż.
OsobyPROFIL NAUKOWYGoogle Scholar -https://scholar.google.com/citations?hl=pl&user=eIR5wi4AAAAJ&view_op=list_worksResearch Gate – https://www.researchgate.net/profile/Przemyslaw_KowalScopus – https://www.scopus.com/authid/detail.uri?authorId=7006593853WYKSZTAŁCENIEdr inż.(2016): Uniwersytet Warmińsko Mazurski w Olsztynie, Wydział Biologiimgr inż. (2009): Uniwersytet Warmińsko Mazurski w Olsztynie; Wydział Ochrony Środowiska...
-
Molecular basis of essentiality of early critical steps in the lipopolysaccharide biogenesis in Escherichia coli K-12: requirement of MsbA, cardiolipin, LpxL, LpxM and GcvB
PublikacjaTo identify the physiological factors that limit the growth of Escherichia coli K-12 strains synthesizing minimal lipopolysaccharide (LPS), we describe the first construction of strains devoid of the entire waa locus and concomitantly lacking all three acyltransferases (LpxL/LpxM/LpxP), synthesizing minimal lipid IVA derivatives with a restricted ability to grow at around 21 °C. Suppressors restoring growth up to 37 °C of Δ(gmhD-waaA)...
-
Accidents, victims and risk levels on regional roads in pomorskie voivodeship, 2017-2019 - Elderly people accidents
Dane BadawczeData contain risk classification on regional roads (voivodeship roads) in pomorskie voivodeship in 2017-2019, risk group: elderly people (65+) - drivers, passengers and . vulnerable road user. Measures used to assess the level of risk are (5 classes low, low to medium, medium, medium to high, high):
-
Accidents, victims and risk levels on regional roads in pomorskie voivodeship, 2017-2019 - Child accidents
Dane BadawczeData contain risk classification on regional roads (voivodeship roads) in pomorskie voivodeship in 2017-2019, risk group: children - drivers, passengers and . vulnerable road user.. Measures used to assess the level of risk are (5 classes low, low to medium, medium, medium to high, high):
-
Language of Benefits as a Novel Tool for Improving Website Personalization
PublikacjaA properly designed website allows the user to search for information faster, and more accurately. The information content of the website should be also adapted to the needs of the user. The purpose of this article is to present a novel Language of Benefits (LoB) approach to facilitate the use of websites for individual user groups. The LoB approach is an approach addressed to IT Analysts, to facilitate the process of web design,...
-
Performance Analysis of Interaction between Smart Glasses and Smart Objects Using Image-Based Object Identification
PublikacjaWe propose the use of smart glasses to collaborate with smart objects in the Internet of Things environment. Particularly we are focusing on new interaction methods and the analysis of acceptable reaction times in the process of object recognition using smart glasses. We evaluated the proposed method using user studies and experiments with three different smart glasses: Google Glass, Epson Moverio, and the developed eGlasses platform....
-
Bogdan Wiszniewski prof. dr hab. inż.
OsobyBogdan Wiszniewski ukończył studia na Politechnice Gdańskiej w 1977 r. uzyskując tytuł zawodowy magistra inżyniera elektroniki, specjalności automatyka i informatyka. W 1984 r. uzyskał stopień naukowy doktora nauk technicznych, w 1998 r. doktora habilitowanego, a w 2006 r. tytuł profesora. Wykładał na uniwersytetach w Kanadzie, Stanach Zjednoczonych i Wielkiej Brytanii. Był głównym wykonawcą lub koordynatorem kilkunastu krajowych...
-
Role of the disulfide bond in stabilizing and folding of the fimbrial protein DraE from uropathogenic Escherichia coli
PublikacjaDr fimbriae are homopolymeric adhesive organelles of uropathogenic Escherichia coli composed of DraE subunits, responsible for the attachment to host cells. These structures are characterized by enormously high stability resulting from the structural properties of an Ig-like fold of DraE. One feature of DraE and other fimbrial subunits that makes them peculiar among Ig-like domain-containing proteins is a conserved disulfide bond...
-
Improving Re-rankCCP with Rules Quality Measures
PublikacjaRecommender Systems are software tools and techniques which aim at suggesting new items that may possibly be of interest to a user. Context-Aware Recommender Systems exploit contextual information to provide more adequate recommendations. In this paper we described a modification of an existing contextual post-filtering algorithm which uses rules-like user representation called Contextual Conditional Preferences. We extended the...
-
Dorota Dominika Kamrowska-Załuska dr hab. inż. arch.
OsobyDr hab. inż. arch. Dorota Kamrowska-Załuska, profesorka Politechniki Gdańskiej, jest od 2002 roku związana z Katedrą Urbanistyki i Planowania Regionalnego na Wydziale Architektury Politechniki Gdańskiej. Wieloletnia Kierowniczka Studiów Podyplomowych Urbanistyki i Gospodarki Przestrzennej „Projektowanie przestrzeni i zarządzanie”, odbyła staże badawcze w kilku instytucjach badawczych w tym Massachusetts Institute of Technology...
-
An Ontology-based Contextual Pre-filtering Technique for Recommender Systems
PublikacjaContext-aware Recommender Systems aim to provide users with the most adequate recommendations for their current situation. However, an exact context obtained from a user could be too specific and may not have enough data for accurate rating prediction. This is known as the data sparsity problem. Moreover, often user preference representation depends on the domain or the specific recommendation approach used. Therefore, a big effort...
-
Identification of Substrates of Cytoplasmic Peptidyl-Prolyl Cis/Trans Isomerases and Their Collective Essentiality in Escherichia Coli
PublikacjaProtein folding often requires molecular chaperones and folding catalysts, such as peptidyl-prolyl cis/trans isomerases (PPIs). The Escherichia coli cytoplasm contains six well-known PPIs, although a requirement of their PPIase activity, the identity of their substrates and relative enzymatic contribution is unknown. Thus, strains lacking all periplasmic and one of the cytoplasmic PPIs were constructed. Measurement of their PPIase...
-
Dariusz Dąbrowski dr hab. inż.
OsobyDariusz Dąbrowski ukończył studia w Instytucie Okrętowym Politechniki Gdańskiej, a w 1987 roku podjął pracę na tej uczelni na stanowisku asystenta w Zakładzie Organizacji Przemysłu Okrętowego w ówczesnym Instytucie Organizacji i Projektowania Systemów Produkcyjnych. W 1990 roku wyjechał na stypendium TEMPUS, UE, i spędził 14 miesięcy na Uniwersytecie w Sheffield, gdzie uczestniczył w programie Master of Business Administration...
-
Online Sound Restoration for Digital Library Applications
PublikacjaA system for sound restoration was conceived and engineered having the following features: no special sound restoration software is needed to perform audio restoration by the user, the process of restoration employs automatic reduction of noise, wow and impulse distortions performed in the online mode, no skills in digital signal processing from the user are needed. The principles of the created system and its features as well...
-
Using contextual conditional preferences for recommendation taska: a case study in the movie domain
PublikacjaRecommendation engines aim to propose users items they are interested in by looking at the user interaction with a system. However, individual interests may be drastically influenced by the context in which decisions are taken. We present an attempt to model user interests via a set of contextual conditional preferences. We show that usage of proposed preferences gives reasonable values of the accuracy and the precision even when...
-
Practical Approach to IP Scheduled Throughput Measurements in Dual Connectivity Systems
PublikacjaIP scheduled throughput defined according to 3GPP TS 36.314 reflects user throughput regardless of traffic characteristics, and therefore has become one of the most important indicators for monitoring Quality of Service (QoS) of the end user in Evolved Universal Terrestrial Radio Access Network (E-UTRAN). However, networks built on a distributed architecture make the above definition impossible to be applied directly due to the...
-
SMART SHOP SERVICES FOR BUILDING CUSTOMER-ORIENTED SCENARIOS
PublikacjaThe shops of today mostly support the customer by offering him or her products based on basic relationships between products viewed or ordered by users with similar tastes. This common approach may fail in many cases especially when the user does not have sufficient knowledge about the market, or when he or she wants to build a set of products in more than one shop. New categories of smart shop services are proposed in order to...
-
Anna Lisowska-Oleksiak prof. dr hab.
OsobyAnna Lisowska-Oleksiak, born in 1952, has been working at GUT since 1977. Currently is employed at the Faculty of Chemistry as a full professor. She was employed as a research assistant at the University of St Andrews in the group of C. A. Vincent and P.G. Bruce (1991-1994). She completed a two-month research internship in CEA Grenoble (2011). Anna Lisowska-Oleksiak obtained her MSc in chemistry at Nicolaus Copernicus University...
-
IEEE Conference on Virtual Reality and 3D User Interfaces (IEEE Virtual Reality Conference)
Konferencje -
Virtual immersive environments
PublikacjaYet a higher level of active systems may be achieved when users are fully immersed in an interface which is a 3D computer generated virtual world and can interact with surrounding objects of that world as they were in a real one. This is the issue covered by Chapter 7. Interaction in such a world is both multidimensional and multimodal, with the possibility of free movement of the user in any direction and the simultaneous stimulation...
-
Image projection in Immersive 3D Visualization Laboratory
PublikacjaIn recent years, many centers in the world attempted to build a virtual reality laboratory. The main idea of such laboratory is to allow the user to “immerse” into and move in a computer-generated virtual world. In the paper, the underlying principles of the system of virtual reality (VR) are described. The selected implementations constructed by the research centers of the world are also presented. The cave automatic virtual environment...
-
Deep learning for recommending subscription-limited documents
PublikacjaDocuments recommendation for a commercial, subscription-based online platform is important due to the difficulty in navigation through a large volume and diversity of content available to clients. However, this is also a challenging task due to the number of new documents added every day and decreasing relevance of older contents. To solve this problem, we propose deep neural network architecture that combines autoencoder with...
-
Multicopy Suppressor Analysis of Strains Lacking Cytoplasmic Peptidyl-Prolyl cis/trans Isomerases Identifies Three New PPIase Activities in Escherichia coli That Includes the DksA Transcription Factor
PublikacjaConsistent with a role in catalyzing rate-limiting step of protein folding, removal of genes encoding cytoplasmic protein folding catalysts belonging to the family of peptidyl-prolyl cis/trans isomerases (PPIs) in Escherichia coli confers conditional lethality. To address the molecular basis of the essentiality of PPIs, a multicopy suppressor approach revealed that overexpression of genes encoding chaperones (DnaK/J and GroL/S),...
-
Words context analysis for improvement of information retrieval
PublikacjaIn the article we present an approach to improvement of retrieval informationfrom large text collections using words context vectors. The vectorshave been created analyzing English Wikipedia with Hyperspace Analogue to Language model of words similarity. For test phrases we evaluate retrieval with direct user queries as well as retrieval with context vectors of these queries. The results indicate that the proposed method can not...
-
Human-Computer Interface Based on Visual Lip Movement and Gesture Recognition
PublikacjaThe multimodal human-computer interface (HCI) called LipMouse is presented, allowing a user to work on a computer using movements and gestures made with his/her mouth only. Algorithms for lip movement tracking and lip gesture recognition are presented in details. User face images are captured with a standard webcam. Face detection is based on a cascade of boosted classifiers using Haar-like features. A mouth region is located in...
-
A CONTEXT IN RECOMMENDER SYSTEMS
PublikacjaRecommender systems aim to propose potentially interesting items to a user based on his preferences or previous interaction with the system. In the last decade, researcher found out that known recommendation techniques are not sufficient to predict user decisions. It has been noticed that user preferences strongly depend on the context in which he currently is. This raises new challenges for the researchers such as how to obtain...