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Wyniki wyszukiwania dla: C. PALMIOLEOPHILA
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Mitotic catastrophe followed by necrosis versus pro-survival autophagy - two opposite cellular effects triggered upon C-1311 treatment in MCF-7 cells
PublikacjaPrzeprowadzone badania miały na celu określenie zdolności imidazoakrydonu C-1311 do indukcji katastrofy mitotycznej, nekrozy i autofagii w komórkach ludzkiego raka piersi MCF-7. Wszystkie eksperymenty przeprowadzone zostały przy stężeniu hamującym proliferację komórek nowotworowych w 80%. Wykazano, że pochodna C-1311 powoduje przejściową akumulację komórek MCF-7 w fazie G2 cyklu życiowego (59% po 48 godz. inkubacji) z równoczesnym...
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Projektowanie, synteza oraz badanie aktywności biologicznej amidosiarczanowych inhibitorów sulfatazy steroidowej zawierających w swojej konstytucji ugrupowania fosforowe lub wiązania C-F
PublikacjaWedług Światowej Organizacji Zdrowia (WHO) estrogeny są jednymi z głównych czynników stymulujących wzrost nowotworów hormonozależnych. Dlatego też, projektowanie oraz synteza nowych, skuteczniejszych środków wpływających na biosyntezę estrogenów stanowi ogromne wyzwanie dla współczesnej medycyny. W ostatnich latach liczne ośrodki naukowe na całym świecie prowadzą intensywne badania związane z poszukiwaniem nowych, skutecznych inhibitorów...
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Manganese–Cobalt Based Spinel Coatings Processed by Electrophoretic Deposition Method: The Influence of Sintering on Degradation Issues of Solid Oxide Cell Oxygen Electrodes at 750 °C
PublikacjaThis paper seeks to examine how the Mn–Co spinel interconnect coating microstructure can influence Cr contamination in an oxygen electrode of intermediate temperature solid oxide cells, at an operating temperature of 750 °C. A Mn–Co spinel coating is processed on Crofer 22 APU substrates by electrophoretic deposition, and subsequently sintered, following both the one-step and two-step sintering, in order to obtain significantly...
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The effect of high pressure and sub-zero temperature on total antioxidant capacity and the content of vitamin C, fatty acids and secondary products of lipid oxidation in human milk
PublikacjaThe objective of this study was to compare of the effects of high pressure of 193 MPa at - 20°C and Low Temperature Long Time pasteurization (LTLT or holder pasteurization, 62,5°C; 30 min) on the content and composition of fatty acids (FAs), concentrations of secondary products of lipid oxidation (TBARS), the total antioxidant capacity (TAC), total vitamin C and ascorbic acid (AsA) content in human milk. It was shown that no significant...
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The overexpression of CPR and P450 3A4 in pancreatic cancer cells changes the metabolic profile and increases the cytotoxicity and pro-apoptotic activity of acridine antitumor agent, C-1748
PublikacjaDrug resistance is one of the major cause of pancreatic cancer treatment failure. Thus, it is still imperative to develop new active compounds and novel approach to improve drug efficacy. Here we present 9-amino-1-nitroacridine antitumor agent, C-1748, developed in our laboratory, as a candidate for pancreatic cancer treatment. We examined (i) the cellular response of pancreatic cancer cell lines: Panc-1, MiaPaCa-2, BxPC-3 and...
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The time-dependent cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to cancer LNCaP cells
Dane BadawczeThe time-dependent (1, 24, 48, and 72 h) cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to cancer LNCaP cells performed by Confocal Laser Scanning Microscopy (63× magnification; ZEISS LSM T-PMT, Magdeburg, Germany). Based on the fluorescence properties of these compounds, green and orange fluorescence...
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The time-dependent cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to cancer H460 cells
Dane BadawczeThe time-dependent (1, 24, 48, and 72 h) cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to cancer H460 cells performed by Confocal Laser Scanning Microscopy (63× magnification; ZEISS LSM T-PMT, Magdeburg, Germany). Based on the fluorescence properties of these compounds, green and orange fluorescence...
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The time-dependent cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to normal PNT1A cells
Dane BadawczeThe time-dependent (1, 24, 48, and 72 h) cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to normal PNT1A cells performed by Confocal Laser Scanning Microscopy (63× magnification; ZEISS LSM T-PMT, Magdeburg, Germany). Based on the fluorescence properties of these compounds, green and orange fluorescence...
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Anna Brillowska-Dąbrowska dr hab. inż.
OsobyAnna Brillowska-Dąbrowska, urodzona w 1971 r. w Gdańsku, ukończyła w 1996 r. studia magisterskie na kierunku Biotechnologia, na Wydziale Chemicznym PG. Stopień doktora uzyskała po ukończeniu Studium Doktoranckiego przy Wydziale Chemicznym PG w 2001 r. W 2013 r. uzyskała stopień doktora habilitowanego. W 2004 r. została zatrudniona na stanowisku naukowiec w Statens Serum Institut w Danii w Jednostce Mikologii i Parazytologii. W...
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The time-dependent cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to cancer Du-145 cells
Dane BadawczeThe time-dependent (1, 24, 48, and 72 h) cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to cancer Du-145 cells performed by Confocal Laser Scanning Microscopy (63× magnification; ZEISS LSM T-PMT, Magdeburg, Germany). Based on the fluorescence properties of these compounds, green and orange fluorescence...
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The time-dependent cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to normal MRC-5 cells
Dane BadawczeThe time-dependent (1, 24, 48, and 72 h) cellular uptake of C−2028, CD−C−2028, QDgreen−C−2028, and QDgreen−CD−FA−C−2028 conjugates at IC80 value to normal MRC-5 cells performed by Confocal Laser Scanning Microscopy (63× magnification; ZEISS LSM T-PMT, Magdeburg, Germany). Based on the fluorescence properties of these compounds, green and orange fluorescence...
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University Politehnica of Bucharest Scientific Bulletin Series C-Electrical Engineering and Computer Science
Czasopisma -
Antitumor imidazoacridinone derivative C-1311 induces cell cycle arrest and cellular senescence-like phenotypic changes in human non-small lung A549 cancer cells
PublikacjaPrzeprowadzone badania miały na celu zbadanie rodzaju odpowiedzi komórkowej indukowanej przez pochodną C1311 w komórkach ludzkiego, niedrobnokomórkowego raka płuc A549, wyselekcjonowanych do badań ze względu na wysoką wrażliwość na działanie pochodnej C-1311. Wszystkie eksperymenty przeprowadzone zostały przy stężeniu hamującym proliferację komórek nowotworowych w 80%. Badania z wykorzystaniem techniki cytometrii przepływowej oraz...
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Effect of Manual Therapy Compared to Ibuprofen on Primary Dysmenorrhea in Young Women—Concentration Assessment of C-Reactive Protein, Vascular Endothelial Growth Factor, Prostaglandins and Sex Hormones
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Sytuacja pracodawców zatrudniających pracowników na umowy na czas określony po wyroku ETS z dnia 13 marca 2014 r. (C 38/13)
PublikacjaWyrokiem z dnia 13 marca 2014 br. (sygn. akt C 38/13) Europejski Trybunał Sprawiedliwości uznał art. 33 kp za niezgodny z prawem unijnym. Wobec takiego stanowiska w artykule przeanalizowano sytuację pracodawców zatrudniających pracowników na umowy na czas określony. W istocie rozwiązanie zawarte przez ustawodawcę we wskazanym przepisie od dawna wzbudzało kontrowersje w doktrynie i orzecznictwie - jednak nie tylko w zakresie jednolitego...
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A strong preference for the TA/TA dinucleotide step discovered for an acridine-based, potent antitumor dsDNA intercalator, C-1305: NMR-driven structural and sequence-specificity studies
PublikacjaTriazoloacridinone C-1305, a potent antitumor agent recommended for Phase I clinical trials, exhibits high activity towards a wide range of experimental colon carcinomas, in many cases associated with complete tumor regression. C-1305 is a well-established dsDNA intercalator, yet no information on its mode of binding into DNA is available to date. Herein, we present the NMR-driven and MD-refined reconstruction of the 3D structures...
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Novel complexes possessing Hg–(Cl, Br, I)⋯O=C halogen bonding and unusual Hg₂S₂(Br/I)₄ kernel. The usefulness of τ₄′ structural parameter
PublikacjaOne mononuclear and two binuclear Hg(II) complexes have been synthesized and characterized by X-ray diffraction, ATR IR and Hirshfeld surface analysis. Single-crystal X-ray diffraction showed that binuclear compounds are centrosymmetric and isostructural. All complexes form bifurcated intermolecular N–H···O hydrogen bonds that contribute to a formation of the centrosymmetric dimers. In binuclear complexes, sulfur atoms of thiourea...
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SEM images of symmetrical cell interface with Sr1.05Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at 800 °C, 900 °C and 1000 °C
Dane BadawczeThis dataset contains images of polished cross section of symmetrical cell interface with Sr1.05Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at three different temperatures 800 °C, 900 °C and 1000 °C. Images were obtained using a PhenomXL (Thermo Fisher Scientific, the Netherlands) scanning electron microscope (SEM) with an accelerating...
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SEM images of symmetrical cell interface with Sr0.90Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at 800 °C, 900 °C and 1000 °C
Dane BadawczeThis dataset contains images of polished cross section of symmetrical cell interface with Sr0.90Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at three different temperatures 800 °C, 900 °C and 1000 °C. Images were obtained using a PhenomXL (Thermo Fisher Scientific, the Netherlands) scanning electron microscope (SEM) with an accelerating...
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SEM images of symmetrical cell interface with Sr0.95Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at 800 °C, 900 °C and 1000 °C
Dane BadawczeThis dataset contains images of polished cross section of symmetrical cell interface with Sr0.95Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at three different temperatures 800 °C, 900 °C and 1000 °C. Images were obtained using a PhenomXL (Thermo Fisher Scientific, the Netherlands) scanning electron microscope (SEM) with an accelerating...
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SEM images of symmetrical cell interface with Sr1.00Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at 800 °C, 900 °C and 1000 °C
Dane BadawczeThis dataset contains images of polished cross section of symmetrical cell interface with Sr1.00Ti0.30Fe0.70O3-d electrodes and CGO-20 substrate sintered at three different temperatures 800 °C, 900 °C and 1000 °C. Images were obtained using a PhenomXL (Thermo Fisher Scientific, the Netherlands) scanning electron microscope (SEM) with an accelerating...
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Effect of C-1748 derivatives on the biofilm formation of C. albicans ATCC 10231 cells
Dane BadawczeThe datasets contain the results of the impact of five C-1748 derivatives (IKE28 - IKE32) on the biofilm formation of Candida albicans strain ATCC 10231 cells. Photographic documentation prepared with the TECAN Spark 10M titration plate reader.
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Effect of C-1748 derivatives on the morphological transformation of C. albicans ATCC 10231 cells
Dane BadawczeThe datasets contain the results of the impact of five C-1748 derivatives (IKE28 - IKE32) on morphological transformation of Candida albicans strain ATCC 10231 cells. Photographic documentation prepared with the TECAN Spark 10M titration plate reader.
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Ireneusz Kreja dr hab. inż.
OsobyAbsolwent klasy matematycznej I Liceum Ogólnokształcącego w Gdańsku im. Mikołaja Kopernika (1974). Absolwent Wydziału Budownictwa Lądowego Politechniki Gdańskiej (1979). Od 1979 pracuje na PG. W 1989 uzyskał doktorat (z wyróżnieniem), na Wydziale Budownictwa Lądowego, a w 2008 habilitował się (również z wyróżnieniem) na Wydziale Inżynierii Lądowej i Środowiska PG. Od 2011 jest profesorem PG. Na Politechnice Gdańskiej pełnił funkcje:...
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Determination of the minimum inhibitory concentration of C-1311 derivatives (C-1296, C-1410, Compound 1, Compound 1-R8) against Candida strains
Dane BadawczeThe datasets contain the results of determining the minimum inhibitory concentration of imidazoacridinone derivatives against C. albicans ATCC 10231, C. glabrata ATCC 90030, C. krusei ATCC 6258 and C. parapsilosis ATCC 22019 and C. albicans clinical strains by the modified M27-A3 specified by the CLSI.
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Cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).
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<p>Mechano-signalling, induced by fullerene C<sub>60</sub> nanofilms, arrests the cell cycle in the G2/M phase and decreases proliferation of liver cancer cells</p>
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In vitro biological evaluation of a novel folic acid-targeted receptor quantum dot−β−cyclodextrin carrier for C-2028 unsymmetrical bisacridine in the treatment of human lung and prostate cancers
PublikacjaTraditional small-molecule chemotherapeutics usually do not distinguish tumors from healthy tissues. However, nanotechnology creates nanocarriers that selectively deliver drugs to their site of action. This work is the next step in the development of the quantum dot−β−cyclodextrin−folic acid (QD−β−CD−FA) platform for targeted and selected delivery of C−2028 unsymmetrical bisacridine in cancer therapy.Herein, we report an initial...
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JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
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Structure-activity relationship study of a small cyclic peptide H-c[Lys-Pro-Glu]-Arg-OH: a potent inhibitor of Vascular Endothelial Growth Factor interaction with Neuropilin-1
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Cytotoxicity of C-2028, QDgreen, QDred, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst LNCaP cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen, QDred, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst LNCaP cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).
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Series resistance (at 800 °C - 500 °C) of the Sr0.86Ti0.65Fe0.35O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the ohmic contribution of differently sintered Sr0.86Ti0.65Fe0.35O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C, 1000 °C and 1050 °C. The measurement temperature range was between 800 °C and 500 °C in stationary air. Results converted to electrode surfaces area.
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Series resistance (at 800 °C - 500 °C) of the SrTi0.50Fe0.50O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the ohmic contribution of differently sintered Sr0Ti0.50Fe0.50O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C and 1000 °C. The measurement temperature range was between 800 °C and 500 °C with synthetic ari flow (21% O2, 40 ml min-1). Results converted to electrode...
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Series resistance (at 800 °C - 500 °C) of the SrTi0.30Fe0.70O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the ohmic contribution of differently sintered Sr0Ti0.30Fe0.70O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C and 1000 °C. The measurement temperature range was between 800 °C and 500 °C with synthetic ari flow (21% O2, 40 ml min-1). Results converted to electrode...
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SEM micrographs of diamond-phase (sp3-C) rich boron-doped carbon nanowalls (sp2-C)
Dane BadawczeThis dataset contains the Scanning Electron Microscopy (SEM) micrographs taken for rich boron-doped carbon nanowalls structures, with different boron addition during the synthesis process and different CVD synthesis duration. The [B]/[C] ratios in the plasma were set to 0k, 1.2k, 2k and 5k ppm. The time of growth was ranging between 4 and 9 hours. This...
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Series resistance (at 800 °C - 500 °C) of the SrTi0.65Fe0.35O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the ohmic contribution of differently sintered Sr0Ti0.65Fe0.35O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C and 1000 °C. The measurement temperature range was between 800 °C and 500 °C with synthetic ari flow (21% O2, 40 ml min-1). Results converted to electrode...
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Jacek Stefański prof. dr hab. inż.
OsobyJacek Stefański ukończył studia na Wydziale Elektroniki Politechniki Gdańskiej (PG) w 1993 r. W 2000 r. uzyskał stopień doktora nauk technicznych w dyscyplinie telekomunikacja, w 2012 r. stopień doktora habilitowanego, natomiast w 2020 r. tytuł profesora nauk inżynieryjno-technicznych. Obecnie pracuje na stanowisku profesora w Katedrze Systemów i Sieci Radiokomunikacyjnych (KSiSR) PG. W latach 2005-2009 był zatrudniony w Instytucie...
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Cytotoxicity of C-2028, QDgreen, QDred, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst Du-145 cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen, QDred, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).
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Analiza strukturalna silanotiolanów : wpływ centrów kwasowych na zmiany w układzie wiązań SI-O-C oraz SI-S grupy sialkoksysilanotiolanowej w ciele stałym / J. Chojnacki.
PublikacjaW pracy przedstawiono wyniki badań strukturalnych silanotiolanów metali. Wyniki pochodzące z rentgenowskiej analizy strukturalnej zostały zinterpretowane w oparciu o rezultaty obliczeń kwantowo-mechanicznych. Wyznaczono 46 nowych struktur rentgenowskich silanotiolanów i przeanalizowano je łącznie z wynikami badań strukturalnych innych autorów. Zebrano i usystematyzowano wyniki rentgenowskiej analizy strukturalnej dla wszystkich...
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Significant Decrease in Glycated Hemoglobin, 2h-Post-Load Glucose and High-Sensitivity C-Reactive Protein Levels in Patients with Abnormal Body Mass Index after Therapy with Manual Lymphatic Drainage
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Erratum to “The kinetics of phenol decomposition under UV irradiation with and without H2O2 on TiO2, Fe–TiO2 and Fe–C–TiO2 photocatalysts” [Appl. Catal. B: Environ. 65 (2006) 86–92]
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Ustna opinia uzupełniająca dotycząca projektu budowlanego, wykonawczego i realizowanego procesu budowlanego obiektu Międzynarodowego Centrum Konferencyjnego w Katowicach (Sygn. akt II C 889/13/7)
PublikacjaNa zapytanie sądu oraz zainteresowanych stron będących w sporze udzielano odpowiedzi na wątpliwości i wyjaśniano warunki i skutki czasowe, organizacyjne oraz finansowe dotyczące całego procesu inwestycyjnego obejmującego projektowanie i realizację robót budowlanych prowadzonych na obiekcie MCK w Katowicach.
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Area specific resistance (at 800 °C - 500 °C) of the Sr0.86Ti0.65Fe0.35O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the polarization resistance of differently sintered Sr0.86Ti0.65Fe0.35O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C, 1000 °C and 1050 °C. The measurement temperature range was between 800 °C and 500 °C in stationary air. Results converted to electrode surfaces...
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Area specific resistance (at 800 °C - 500 °C) of the SrTi0.50Fe0.50O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the polarization resistance of differently sintered SrTi0.50Fe0.50O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C and 1000 °C. The measurement temperature range was between 800 °C and 500 °C with synthetic air flow (21% O2, 40 ml min-1). Results converted to...
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Area specific resistance (at 800 °C - 500 °C) of the SrTi0.30Fe0.70O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the polarization resistance of differently sintered SrTi0.30Fe0.70O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C and 1000 °C. The measurement temperature range was between 800 °C and 500 °C with synthetic air flow (21% O2, 40 ml min-1). Results converted to...
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Area specific resistance (at 800 °C - 500 °C) of the SrTi0.65Fe0.35O3 porous oxygen electrodes sintered at different temperatures
Dane BadawczeIn this dataset are presented results of the polarization resistance of differently sintered SrTi0.65Fe0.35O3 porous oxygen electrodes in symetrical cell. Applied sintering temperatures were 900 °C, 950 °C and 1000 °C. The measurement temperature range was between 800 °C and 500 °C with synthetic air flow (21% O2, 40 ml min-1). Results converted to...
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Paweł Filipkowski dr inż.
Osobymgr inż - Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności, Katedra Mikrobiologii Technicznej i Żywnosci, Prof. Maria Wojtatowicz/ Prof. Waldemar Rymowicz, adiunkt - Uniwersytet Ekonomiczny we Wrocławiu, Wydział Inzynieryjno-Ekonomiczny, Katedra Inżynierii Bioprocesowej, Prof. Tadeusz Miśkiewicz/ Prof. Edward Cybis, dr - Politechnika Gdańska, Wydział Chemiczny, Katedra Mikrobiologii, ś.p. Prof. Józef Kur, Staże w...
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Effect of the Cooling Time in Annealing at 350°C on the Phase Transformation Temperatures of a Ni<sub>5</sub><sub>5</sub>Ti<sub>4</sub><sub>5</sub> wt. Alloy
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Area specific resistance (at 800 °C - 500 °C) of the SrTi0.30Fe0.70O3 porous oxygen electrodes at different oxygen partial pressures
Dane BadawczeIn this dataset are presented results of the polarization resistance of SrTi0.30Fe0.70O3 porous oxygen electrodes sintered at 800 °C. The measurement temperature range was between 800 °C and 500 °C. Applied different oxygen partial pressure flow was: 1%, 20% and 100% pO2. Results converted to electrode surfaces area and dived by two electrodes. All...
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Investigation of the C-1311 glucuronidation: an electrochemical approach
Dane BadawczeThis study was undertaken to investigate the glucuronidation of the compound C-1311 (5-diethylaminoethylamino-8-hydroxyimidazoacridinone – the model anticancer acridine derivative) using electrochemistry/mass spectrometry (EC/MS) as a complementary technique to in vitro (liver microsomes) and in silico approaches.