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Wyniki wyszukiwania dla: UNRESCOARSE GRAINING

Wyniki wyszukiwania dla: UNRESCOARSE GRAINING

  • [AEEiTK, ITiT] Scientific methods of computer data analysis and presentation 2024/2025

    Kursy Online
    • T. E. Berezowski

    {mlang pl} Dyscyplina: AEiE, ITiT Zajęcia obowiązkowe dla doktorantów II roku Prowadzący:  Tomasz Berezowski Liczba godzin: 30 Forma zajęć: wykład/projekt/seminarium {mlang} {mlang en} Discipline: AEiE, ITiT Obligatory course for 2nd-year PhD students Academic teacher: Tomasz Berezowski Total hours of training: 30 teaching hours Course type: Lecture/project/seminar {mlang}      

  • [soft skills] Scientific databases and information skills

    Kursy Online
    • R. Jankowski
    • A. Klej
    • M. Szuflita-Żurawska

    {mlang pl} Dyscyplina: wszystkie dyscypliny Zajęcia obowiązkowe dla doktorantów I roku Prowadzący:  Magdalena Szuflita-Żurawska, Biblioteka PG Liczba godzin: 5 Forma zajęć: wykład {mlang} {mlang en} Discipline: all disciplines Obligatory course for 1st-year PhD students Academic teacher: Magdalena Szuflita-Żurawska, GUT Library Total hours of training: 5 teaching hours Course type: lecture {mlang} Soft skills Area...

  • Chapter 11 – Application of Chemical Sensors and Sensor Matrixes to Air Quality Evaluation

    Publikacja

    Indoor and outdoor air quality is one of the key factors influencing human health. However, air quality evaluation is not easy task. Air is a complex system, which is subjected to changes even within short period of time. Progress in analytical methods and analytical tools provides increasingly more reliable information on the condition and quality of indoor and outdoor air. This progress, however, generates an increase in the...

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  • Transformation of Energy Markets: Description, Modeling of Functioning Mechanisms and Determining Development Trends

    Publikacja

    One of the key contemporary economic and social issues today is the global energy transition. Energy transition processes are having a significant impact on the development of world economies, increasing their TFP and leading to an increase in their level of innovation through the transfer of myriad new technologies. These processes also contribute to an increase in foreign direct investment and, consequently, an increase in the...

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  • Wytrzymałość pętli wplatanych na linach podwójnie plecionych

    Cechą wyróżniającą statki żaglowe z grona innych obiektów pływających są żagle. To cecha widoczna, za którą kryją się mniej romantyczne elementy, takie jak maszty, liny i osprzęt. Rozpostarcie białych płócien na maszcie i następnie żeglowanie wymaga sprawnego operowania nimi, co wiąże się z doborem odpowiedniego ich zestawu, ułożenia i napięcia. To maszty są kręgosłupem takielunku, a liny jego mięśniami i ścięgnami. Do poprawnego...

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  • Spatial and Regional Planning Studies

    Kursy Online
    • I. Haxhiaj
    • Ł. Pancewicz

    The course objective is to teach the basic, practical skills of planning for the architects. Three aspects of planning will be taught during the course: building control, regulatory planning and operational planning. The students will explore the role of planning in granting the building permissions, how to prepare the planning (zoning) regulations and finally what are urban design tools, which can be used to coordinate the development...

  • Abdeslam Ennabili Prof.

    Osoby

    Abdeslam Ennabili is Professor, Superior School of Technology, Sidi Mohamed Ben Abdellah University, Fes-Morocco (since 2004), Researcher and Senior Manager (1999-2003) and Assistant Project (1996-1999), Luxembourg University Foundation (FUL), Arlon- Belgium. He earned his PhD in Environmental Sciences (1999) at the FUL, becoming since 2004 the Department of Environmental Sciences and Management, Faculty of Sciences, University...

  • [Soft Skills] Academic writing gr. 4

    Kursy Online
    • A. Klej
    • I. Mokwa-Tarnowska

    {mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów I roku, fakultatywne dla doktorantów II roku Prowadzący:   dr Iwona Mokwa-Tarnowska Liczba godzin: 30 Forma zajęć:  {mlang} {mlang en} Discipline: soft skills Obligatory course for 1st-year PhD students, facultative for 2nd-year PhD students Academic teacher: dr Iwona Mokwa - Tarnowska Total hours of training: 30 teaching hours Course type:  {mlang}

  • [EiF, ZiJ] Qualitative research methods 2021-22

    Kursy Online
    • K. Zięba

    {mlang pl} Dyscyplina: EiF, ZiJ Zajęcia obowiązkowe dla doktorantów I roku Prowadzący:  K. Zięba Liczba godzin: 30 Forma zajęć: laboratoria {mlang} {mlang en} Discipline: EiF, ZiJ Obligatory course for 1st-year PhD students Academic teacher: K. Zięba Total hours of training: 30 teaching hours Course type: Laboratories {mlang}      

  • [AiU] Contemporary research methodology, evaluation and preservation of historic architecture

    Kursy Online
    • R. Jankowski
    • M. Dymnicka
    • S. Kowalski

    {mlang pl} Dyscyplina: architektura i urbanistyka Zajęcia obowiązkowe dla doktorantów II roku Prowadzący:  Assoc. Prof. Dr. Paola Ardizzola Liczba godzin: 30 Forma zajęć: wykład/seminarium {mlang} {mlang en} Discipline: architecture and urbanism Obligatory course for 2nd-year PhD students Academic teachers: Assoc. Prof. Dr. Paola Ardizzola Total hours of training: 30 teaching hours Course type: lecture/seminar {mlang}

  • [Soft Skills] Academic writing gr. 3

    Kursy Online
    • A. Klej
    • I. Mokwa-Tarnowska

    {mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów I roku, fakultatywne dla doktorantów II roku Prowadzący:   dr Iwona Mokwa-Tarnowska Liczba godzin: 30 Forma zajęć:  {mlang} {mlang en} Discipline: soft skills Obligatory course for 1st-year PhD students, facultative for 2nd-year PhD students Academic teacher: dr Iwona Mokwa - Tarnowska Total hours of training: 30 teaching hours Course type:  {mlang}

  • [ZiJ] Management theories I

    Kursy Online
    • A. Parteka

    {mlang pl} Dyscyplina:  Nauki o Zarządzaniu i Jakości Zajęcia obowiązkowe dla doktorantów I i II roku Prowadzący:   prof. dr hab. Wojciech Czakon Liczba godzin: 15 h Forma zajęć: wykład {mlang} {mlang en} Discipline: Management and Quality Obligatory course for 1st and 2nd year PhD students Academic teacher:  prof. dr hab. Wojciech Czakon Total hours of training: 15 teaching hours Course type: lecture {mlang}

  • [EiF] Economic theory - macro

    Kursy Online
    • E. Lechman

    {mlang pl} Dyscyplina:  Ekonomia i Finanse Zajęcia obowiązkowe dla doktorantów I i II roku Prowadzący:   dr hab. Ewa Lechman, prof. F. Reganati Liczba godzin: 30 h Forma zajęć: wykład {mlang} {mlang en} Discipline: Economics and Finance Obligatory course for 1st and 2nd year PhD students Academic teacher:  dr hab. Ewa Lechman, prof. F. Reganati Total hours of training: 30 teaching hours Course type: lecture {mlang}

  • [NCh, IMa] Health Effects of Food Components

    Kursy Online
    • A. Bartoszek-Pączkowska

    {mlang pl} Dyscyplina: nauki chemiczne, inżynieria materiałowa Zajęcia fakultatywne dla doktorantów I i II roku  Prowadzący:  prof. dr hab. inż. Agnieszka Bartoszek-Pączkowska Liczba godzin: 15 Forma zajęć: wykład {mlang} {mlang en} Discipline: chemical sciences, materials engineering Facultative course for 1st and 2nd-year PhD students Academic teachers: prof. dr hab. inż. Agnieszka Bartoszek-Pączkowska Total hours...

  • [EiF] Economic theory - macro

    Kursy Online
    • E. Lechman

    {mlang pl} Dyscyplina: EiF Zajęcia obowiązkowe dla doktorantów I roku Prowadzący:  E. Lechman, F. Reganati Liczba godzin: 30 Forma zajęć: wykład {mlang} {mlang en} Discipline: EiF Obligatory course for 1st-year PhD students Academic teacher: E. Lechman, F. Reganati Total hours of training: 30 teaching hours Course type: lecture {mlang}  

  • [EiF, ZiJ] Quantitative research methods

    Kursy Online
    • P. Paradowski

    {mlang pl} Dyscyplina: EiF, ZiJ Zajęcia obowiązkowe dla doktorantów I roku Prowadzący:  P. Paradowski, LIS&PG Liczba godzin: 30 Forma zajęć: laboratoria {mlang} {mlang en} Discipline: EiF, ZiJ Obligatory course for 1st-year PhD students Academic teacher: P. Paradowski, LIS&PG Total hours of training: 30 teaching hours Course type: Laboratories {mlang}      

  • Surrogate methods in system engineering

    Kursy Online
    • A. Bekasiewicz

    {mlang pl} Dyscyplina:  Automatyka, Elektronika i Elektrotechnika Zajęcia fakultatywne dla doktorantów II roku Prowadzący:   dr hab. inż. Adrian Bekasiewicz Liczba godzin: 15 h Forma zajęć: wykład {mlang} {mlang en} Discipline: control, electronic and electrical engineering Facultative course for 2nd year PhD students Academic teacher:  dr hab. inż. Adrian Bekasiewicz Total hours of training: 15 teaching hours Course...

  • [EiF] [ZiJ] Writing scientific papers for Management and Economics Fields of Science

    Kursy Online
    • A. Parteka
    • A. Klej

    {mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów I i II roku z dyscyplin EiF oraz ZiJ,  Prowadzący:  dr hab inż. Aleksandra Parteka, prof. PG Liczba godzin: 5 Forma zajęć:  {mlang} {mlang en} Discipline: soft skills Obligatory course for 1st and 2nd-year PhD students of EiF and ZiJ disciplines Academic teacher:  dr hab. inż. Aleksandra Parteka, prof. PG Total hours of training: 5 teaching hours Course...

  • [Soft Skills] Writing grant application

    Kursy Online
    • R. Downar-Zapolska
    • J. Baum

    {mlang pl} Dyscyplina: soft skills Zajęcia obowiązkowe dla doktorantów II roku,  Prowadzący:  mgr Renata Downar-Zapolska Liczba godzin: 5 Forma zajęć: online Data:15.06.2023 {mlang} {mlang en} Discipline: soft skills Obligatory course for 2nd-year PhD students Academic teacher: mgr Renata Downar-Zapolska Total hours of training: 5 teaching hours Course type: online Date: 15.06.2023 {mlang}

  • [NF] Physics research methods Part II

    Kursy Online
    • J. Guthmuller

    {mlang pl} Dyscyplina: nauki fizyczne Zajęcia obowiązkowe dla doktorantów I roku Prowadzący:  dr hab. Julien Guthmuller, prof. PG Liczba godzin: 15 Forma zajęć: wykład {mlang} {mlang en} Discipline: physical sciences Obligatory course for 1st-year PhD students Academic teacher: dr hab. Julien Guthmuller, prof. PG Total hours of training: 15 teaching hours Course type: lecture {mlang}  

  • Is data management a new “digitisation”? A change of the role of librarians in the context of changing academic libraries’ tasks

    Publikacja

    - Rok 2018

    Academic libraries’ tasks have been evolving over the years. The changes have been stimulated by appearing of electronic resources, automated library systems, digital libraries and Open Access (OA) repositories. Librarians’ tasks and responsibilities in the academic environment have been evolving in accordance with new tasks they were expected to assume. A few years ago there was a discussion during which an attempt was made to...

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  • CULTURAL DETERMINANTS OF EVIDENCE-BASED HUMAN RESOURCES MANAGEMENT: A CROSS-COUNTRY ANALYSIS

    Purpose: This paper aims at providing comparative analysis of the influence of cultural determinants on the managers’ perceptions of human resources management practices, as a factor conditioning application of evidence-based management. Design/methodology/approach: This article presents the study of 121 managers in Poland, on their perception of HRM practices and analyses the consistency of findings with the Hofstede cultural...

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  • Intercultural interactions at multinational corporations' workplace: Grounded theory.

    Publikacja

    - Journal of Positive Management - Rok 2016

    environments is a new challenge for employees and managers. The aim of the paper is to analyze the social interactions in multicultural environments of multinational corporations (MNCs) as well as to propose a model of intercultural social interactions in MNCs’ specifi c context. Design/methodology/approach: The grounded theory approach was applied to create a model of intercultural interactions in MNCs. The data was obtained during...

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  • Analysis of different tillage implements with respect to reduced fuel consumption, tractor operating speed and its wheel slippage

    Publikacja

    - Rok 2016

    Nowadays the prices of agricultural farm produced products are increasing with ant-speed and the prices of input for raising crops are increasing with rocket-speed. Therefore, there is a dire need to conduct some important studies to innovate the techniques which can lower the costs of crop production. In this context, this study was conducted to evaluate the consumption of fuel at different tillage implements, tractor operating...

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  • Criteria for evaluation and selection of the best offer for the Contract Engineer service

    The purpose of the legal regulations regarding public procurement in EU countries is to ensure effective funds' spending. When assessing and selecting the best offer, the contracting entities have at their disposal many different criteria, including non-price criteria. Their proper selection and application is necessary to ensure the high quality of the ordered product, delivery or service. Making an order for intellectual services,...

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  • PAYMENT TRANSACTIONS’ ENERGY EFFICIENCY

    Publikacja

    - Współpraca Europejska - Rok 2021

    The payment system and infrastructure is a sector that is not given enough attention today in the context of energy efficiency. This sector plays a big role in organizing and ensuring money circulation and funds. It has its value consisting on the one hand of the cost of payment equipment, infrastructure, payment instruments. On other hand, its value consists of the cost of energy for their manufacture and maintenance. The European...

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  • Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.

    Publikacja
    • C. Dates
    • T. Fahmi
    • S. Pyrek
    • A. Yao-Borengasser
    • B. Borowa-Mazgaj
    • S. M. Bratton
    • S. Kadlubar
    • P. Mackenzie
    • R. Haun
    • A. Radominska-Pandya

    - CANCER BIOLOGY & THERAPY - Rok 2015

    Increased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...

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  • Research on Tool Temperature Dependence on Lapping Grains Size

    Publikacja

    - Solid State Phenomena - Rok 2013

    Commonly used as a finishing operation, lapping has been used for achieving ultra-high finishes and close tolerances between mating pieces. Its carried out by applying loose abrasive grains between work and lap surfaces, and causing a relative motion between them resulting in a finish of multi-directional lay. The grains activity (sliding and rolling) in the working gap causes not only the material removal but also the temperature...

  • Acid-aided epoxy-amine curing reaction as reflected in epoxy/Fe3O4 nanocomposites: Chemistry, mechanism, and fracture behavior

    Publikacja
    • M. Jouyandeh
    • M. Shabanian
    • M. Khaleghi
    • S. Paran
    • S. Ghiyasi
    • H. Vahabi
    • K. Formela
    • D. Puglia
    • M. Saeb

    - PROGRESS IN ORGANIC COATINGS - Rok 2018

    This work seeks to answer the question whether or not the presence of acid functional groups accelerate epoxyamine curing reaction. Epoxy/Fe3O4 nanocomposite was considered as a case, where discussions are based on chemistry, mechanism behind curing reactions and fracture behavior influenced by acid assistance to crosslinking. Fe3O4 magnetic nanoparticles (MNPs) with nanosilica decorative layer (B-MNP) were synthesized and subsequently...

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  • Evaluation and cellular responses of modulators of TRF1/TRF2 protein’s function as potential anticancer drugs interfering with telomeric shelterin’s function

    Publikacja

    - Rok 2023

    A number of proteins that interact with telomeres have been identified in human cells, indicating the high plasticity of human nucleoprotein complex organization. The most important complex is the "shelterin" complex, which consists of six proteins: TRF1, TRF2, TIN2, POT1, TPP1. The TRF1 and TRF2 directly bind to telomeric double-stranded DNA and the TIN2 protein. The TIN2 protein also binds to the TPP1 protein, stabilizing the...

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  • The Efficiency and Productivity Evaluation of National Innovation Systems in Europe

    Purpose: An efficient innovation system currently plays a crucial role in creating competitive prevalence, contributing to the economic growth of individual states. The innovation system is influenced by many socioeconomic factors, including in international rankings of innovativeness of economies. These classifications have some limitations. Primarily, they do not examine the efficiency, which means they do not analyze the...

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  • Empirical analysis of tree-based classification models for customer churn prediction

    Publikacja
    • F. E. Usman-Hamza
    • A. O. Balogun
    • S. K. Nasiru
    • L. F. Capretz
    • H. A. Mojeed
    • S. A. Salihu
    • A. G. Akintola
    • M. A. Mabayoje
    • J. B. Awotunde

    - Scientific African - Rok 2023

    Customer churn is a vital and reoccurring problem facing most business industries, particularly the telecommunications industry. Considering the fierce competition among telecommunications firms and the high expenses of attracting and gaining new subscribers, keeping existing loyal subscribers becomes crucial. Early prediction of disgruntled subscribers can assist telecommunications firms in identifying the reasons for churn and...

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  • Joanna Raczek dr inż.

    Wykształcenie 1997 -- 2001 Studia inżynierskie, Wydział Fizyki Technicznej i Matematyki Stosowanej, Politechnika Gdańska. Kierunek: Matematyka, specjalność: Matematyka Stosowana. 2001 -- 2003 Studia magisterskie, Wydział Fizyki Technicznej i Matematyki Stosowanej, Politechnika Gdańska. Kierunek: Matematyka, specjalność: Matematyka Stosowana. 2000 -- 2004 Studia inżynierskie, Wydział Elektroniki, Informatyki i Telekomunikacji,...

  • Using LSTM networks to predict engine condition on large scale data processing framework

    Publikacja

    - Rok 2017

    As the Internet of Things technology is developing rapidly, companies have an ability to observe the health of engine components and constructed systems through collecting signals from sensors. According to output of IoT sensors, companies can build systems to predict the conditions of components. Practically the components are required to be maintained or replaced before the end of life in performing their assigned task. Predicting...

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  • Development and validation of a model that includes two ultrasound parameters and the plasma D-dimer level for predicting malignancy in adnexal masses: an observational study

    Publikacja

    - BMC CANCER - Rok 2019

    Background: Pre-operative discrimination of malignant from benign adnexal masses is crucial for planning additional imaging, preparation, surgery and postoperative care. This study aimed to define key ultrasound and clinical variables and develop a predictive model for calculating preoperative ovarian tumor malignancy risk in a gynecologic oncology referral center. We compared our model to a subjective ultrasound assessment (SUA)...

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  • [IMa] Experimental Methods for Materials Characterisation

    Kursy Online
    • B. Bochentyn
    • M. Szkodo
    • J. Ryl
    • M. Gazda
    • A. D. Mielewczyk-Gryń

    {mlang pl} Dyscyplina: inżynieria materiałowa Zajęcia obowiązkowe dla doktorantów I i II roku Prowadzący:   A. Mielewczyk-Gryń, M. Szkodo, B. Bochentyn, J. Ryl Liczba godzin: 30 Forma zajęć: laboratoria {mlang} {mlang en} Discipline: materials engineering Obligatory course for 1-st and 2nd-year PhD students Academic teachers: M. Gazda, A. Lisowska-Oleksiak, A. Mielewczyk-Gryń, R. Bogdanowicz, T. Klimczuk, Ł. Piszczyk,...

  • [IMa] Experimental Methods for Materials Characterisation - 2024

    Kursy Online
    • T. Klimczuk
    • N. A. Wójcik
    • R. Bogdanowicz
    • M. Strankowski
    • M. Sobaszek
    • J. Karczewski
    • M. Gazda
    • S. Molin

    {mlang pl} Dyscyplina: inżynieria materiałowa Zajęcia obowiązkowe dla doktorantów I i II roku Prowadzący:    R. Bogdanowicz, J. Karczewski, T. Klimczuk, S. Molin, M. Strankowski, N. Wójcik,  Liczba godzin: 30 Forma zajęć: laboratoria {mlang} {mlang en} Discipline: materials engineering Obligatory course for 1-st and 2nd-year PhD students Teachers: R. Bogdanowicz, J. Karczewski, T. Klimczuk, S. Molin, M. Strankowski, N....

  • [ZiJ] Empirical research in Management

    Kursy Online
    • R. Jankowski
    • W. Kucharska

    Dyscyplina: nauki o zarządzaniu i jakości Zajęcia obowiązkowe dla doktorantów I i II roku Prowadzący:  dr inż. Wioleta Kucharska Liczba godzin: 30 Forma zajęć: laboratoria Discipline: management and quality Obligatory course for 1st and 2nd-year PhD students Academic teacher: dr inż. Wioleta Kucharska Total hours of training: 30 teaching hours Course type: laboratories

  • [NCh-bio] Advances in Biotechnology: Protein Folding and Assembly

    Kursy Online
    • R. Jankowski
    • U. Kampowska
    • G. Klein-Raina

    {mlang pl} Dyscyplina: nauki chemiczne Zajęcia obowiązkowe dla doktorantów I i II roku z obszaru biotechnologii Prowadzący:  dr hab. Gracjana Klein-Raina, prof. PG Liczba godzin: 15 Forma zajęć: wykład {mlang} {mlang en} Discipline: chemical sciences Obligatory course for 1st and 2nd-year PhD students from biotechnology area Academic teachers: dr hab. Gracjana Klein-Raina, prof. PG Total hours of training: 15 teaching...

  • [ILiT, IŚGiE] Mathematical methods in engineering

    Kursy Online
    • R. Jankowski
    • R. Sauer
    • M. Skowronek

    {mlang pl} Dyscyplina: inżynieria lądowa i transport; inżynieria środowiska, górnictwo i energetyka Zajęcia obowiązkowe dla doktorantów I i II roku Prowadzący:  dr inż. Roger Sauer, prof. PG Liczba godzin: 15 Forma zajęć: wykład {mlang} {mlang en} Discipline: civil engineering and transport; environmental engineering, mining and power engineering Obligatory course for 1st and 2nd-year PhD students Academic teacher: dr...

  • [Soft Skills] Basic didactic methods

    Kursy Online
    • A. Klej
    • A. Męczkowska-Christiansen

    {mlang pl} Dyscyplina: wszystkie dyscypliny Zajęcia obowiązkowe dla doktorantów I roku Prowadzący:   Liczba godzin: 15 Forma zajęć: wykład {mlang} {mlang en} Discipline: all disciplines Obligatory course for 1st-year PhD students Academic teacher:  Total hours of training: 15 teaching hours Course type: lecture {mlang} Soft skills Area I - didactic skills

  • Improved surface coverage of an optical fibre with nanocrystalline diamond by the application of dip-coating seeding

    Growth processes of diamond thin films on the fused silica optical fibres (10 cm in length) were investigated at various temperatures. Fused silica pre-treatment by dip-coating in a dispersion consisting of detonation nanodiamond (DND) in dimethyl sulfoxide (DMSO) with polyvinyl alcohol (PVA) was applied. Nanocrystalline diamond (NCD) films were deposited on the fibres using the microwave plasma assisted chemical vapour deposition...

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  • Hydrochar-nanoparticle integration for arsenic removal from wastewater: Challenges, possible solutions, and future horizon

    Publikacja

    - ENVIRONMENTAL RESEARCH - Rok 2023

    Arsenic (As) contamination poses a significant threat to human health, ecosystems, and agriculture, with levels ranging from 12 to 75% attributed to mine waste and stream sediments. This naturally element is abundant in Earth's crust and gets released into the environment through mining and rock processing, causing ≈363 million people to depend on As-contaminated groundwater. To combat this issue, introducing a sustainable hydrochar...

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  • Activating Public Space: How to Promote Physical Activity in Urban Environment

    Physical activity is an essential component of a healthy lifestyle. The quality and equipment of urban public space plays an important role in promoting physical activity among people (residents, tourists). In order for recreation and sports activities to be undertaken willingly, in a safe and comprehensive manner, certain spatial conditions and requirements must be met. The distinctive feature of contemporary large cities is the...

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  • Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the antitumor imidazoacridinone C-1311 in human hepatoma cells

    There is increasing evidence that the expression level of drug metabolic enzymes affects the final cellular response following drug treatment. Moreover, anti-tumour agents may modulate enzymatic activity and/or cellular expression of metabolic enzymes in tumour cells. We investigated the influence of CYP3A4 overexpression on the cellular response induced by the anti-tumour agent C-1311 in hepatoma cells. C-1311-mediated CYP3A4...

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  • CE-MS and GC-MS as “Green” and Complementary Methods for the Analysis of Biogenic Amines in Wine

    Publikacja

    - Food Analytical Methods - Rok 2018

    Two novel complementary analytical methods, namely an extraction-free capillary electrophoresis coupled to mass spectrometry (CE-MS) and direct immersion-solid-phase microextraction combined with gas chromatography-mass spectrometry (DI-SPME-GC-MS), have been developed and successfully applied for the determination of biogenic amines (BAs) in wine and fruit wine. They have been rigorously compared to each other in terms of various...

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  • Insights into the microbial community of treated wastewater, its year-round variability and impact on the receiver, using cultivation, microscopy and amplicon-based methods

    Apart from chemical constituents, wastewater treatment plant (WWTP) effluents also release microorganisms that can be important to the receiving water bodies either from a sanitary point of view, or taking to the account the biogeochemical potential of the recipients. However, little is known about the treated wastewater microbial community, its composition, seasonal changes, functions and fate in the waters of the receiver. Thus,...

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  • Marcin Niedopytalski Ekspert ds. Ochrony Osób, Strzelectwa i Prawa Konstytucyjnego

    Osoby

    Marcin Niedopytalski to uznany ekspert z 25-letnim doświadczeniem w dziedzinie ochrony i bezpieczeństwa, autor wielu specjalistycznych książek, naukowiec, a także badacz i obserwator w szeroko rozumianej sferze ochrony. Jego rozległe kompetencje obejmują wiele kluczowych obszarów, takich jak zarządzanie kryzysowe, ochrona VIP-ów, samoobrona, strzelectwo, a także ratownictwo medyczne. Marcin rozpoczął swoją karierę w ochronie bardzo...

  • Electrochemistry meets enzymes: Investigation of the biotransformation pathway of C-1311 based on electrochemical simulation in comparison to in vitro methods.

    Publikacja

    The knowledge of the metabolic pathways and the biotransformation of new drugs is one of the major challenges in pharmaceutical research. It is crucial for elucidation of degradation routes of the new biologically active compounds, especially in the area of possible toxicity. Conventional in vitro drug metabolism studies are based on incubating drug candidate with e.g. hepatocytes or, most importantly, liver cell microsomes and...

  • Kreatywna destrukcja uniwersytetu = Creative destruction of the university

    Autorzy podejmują problematykę zmian we współczesnym uniwersytecie. Wychodząc z założenia, że celem uniwersytetu jest, obok kształcenia masowego, wykształcenie elity przedsiębiorców intelektualnych przyszłych liderów społeczeństwa wiedzy, zaproponowano twórczą destrukcję organizacji uczelni, której istotą jest przeniesienie osi organizacyjnej z podstawowych jednostek uczelni, jakimi są wydziały na zespoły, a osi koordynacyjnej...

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