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Search results for: MORRIS WATER MAZE-SCHIZOPHRENIA-SPATIAL LEARNING-MUSCARINIC RECEPTORS
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Activation of Metabotropic Glutamate Receptor (mGlu2) and Muscarinic Receptors (M1, M4, and M5), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis
PublicationThe Morris water maze (MWM) is regarded as one of the most popular tests for detecting spatial memory in rodents. Long-term potentiation and cGMP synthesis seem to be among the crucial factors involved in this type of learning. Muscarinic (M1, M4, and M5 receptors) and metabotropic glutamate (mGlu) receptors are important targets in the search for antipsychotic drugs with the potency to treat cognitive disabilities associated with...
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Serotonergic–Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms
PublicationRecent studies revealed that the activation of serotonergic 5-HT1A and muscarinic M1, M4, or M5 receptors prevent MK-801-induced cognitive impairments in animal models. In the present study, the effectiveness of the simultaneous activation of 5-HT1A and muscarinic receptors at preventing MK-801-induced cognitive deficits in novel object recognition (NOR) or Y-maze tests was investigated. Activators of 5-HT1A (F15599), M1 (VU0357017),...
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An application of blended and collaborative learning in spatial planning course
PublicationSpatial Planning is a master course for graduate students of Environmental Engineering. The course is based on assumptions that students’ future work will be connected with spatial planning, and spatial issues will have an influence on their everyday lives. To familiarize students with environmental issues in planning, the teams of students get an assignment to design an urban space, waterfront along a stream. The whole project...
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The Role of Dopaminergic Genes in Probabilistic Reinforcement Learning in Schizophrenia Spectrum Disorders
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Confirmation Bias in the Course of Instructed Reinforcement Learning in Schizophrenia-Spectrum Disorders
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Molecular Dynamics Study of the Internal Water Molecules in Vasopressin and Oxytocin Receptors
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Detection of People Swimming in Water Reservoirs with the Use of Multimodal Imaging and Machine Learning
PublicationEvery year in many countries, there are fatal unintentional drownings in different water reservoirs like swimming pools, lakes, seas, or oceans. The existing threats of this type require creating a method that could automatically supervise such places to increase the safety of bathers. This work aimed to create methods and prototype solutions for detecting people bathing in water reservoirs using a multimodal imaging system and...
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Chemometrics in monitoring spatial and temporal variations in drinking water quality
PublicationOpracowanie przedstawia wyniki zastosowania wybranych technik chemometrycznych w monitoringu okresowych i powierzchniowych zmian jakości wody pitnej na podstawie wyników oznaczeń chloro i bromopochodnych produktów dezynfekcji wody w 12 dzielnicach w Gdańsku w okresie 1993-2000. Na podstawie wyników analizy podobieństwa lokalizacje podzielono na dwie grupy dzielnic różniących się jakością wody pitnej spowodowanej różnicami wynikającymi...
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Spatial Differences in the Chemical Composition of Surface Water in the Hornsund Fjord Area: A Statistical Analysis with A Focus on Local Pollution Sources
PublicationSurface catchments in Svalbard are sensitive to external pollution, and yet what is frequently considered external contamination may originate from local sources and natural processes. In this work, we analyze the chemical composition of surface waters in the catchments surrounding the Polish Polar Station in Svalbard, Hornsund fjord area. We have pooled unpublished and already published data describing surface water composition...
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Spatial Analysis of Water Infrastructure Development On Example of Eastern Europe Rural Regions
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Measurement report: Spatial variations in ionic chemistry and water-stable isotopes in the snowpack on glaciers across Svalbard during the 2015–2016 snow accumulation season
PublicationThe Svalbard archipelago, located at the Arctic sea-ice edge between 74 and 81∘ N, is ∼60 % covered by glaciers. The region experiences rapid variations in atmospheric flow during the snow season (from late September to May) and can be affected by air advected from both lower and higher latitudes, which likely impact the chemical composition of snowfall. While long-term changes in Svalbard snow chemistry have been documented in...
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Influence of lightweight structures used in swimming pools and water parks objects on their functionality, building form and spatial-visual effects indoors.
PublicationSpeaking about architecture of swimming facilities and water parks we have in mind their form, function , design and detail, texture and color. A particularly important element of the architecture of these buildings was and still is the structure.
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Procognitive activity of nitric oxide inhibitors and donors in animal models
PublicationNitric oxide is a small gaseous molecule that plays important roles in the majority of biological functions. Impairments of NO-related pathways contribute to the majority of neurological disorders, such as Alzheimer’s disease (AD), and mental disorders, such as schizophrenia. Cognitive decline is one of the most serious impairments accompanying both AD and schizophrenia. In the present study, the activities of NO donors, slow (spermine...
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Dysfunctional prefrontal cortical network activity and interactions following cannabinoid receptor activation.
PublicationCoordinated activity spanning anatomically distributed neuronal networks underpins cognition and mediates limbic-cortical interactions during learning, memory, and decision-making. We used CP55940, a potent agonist of brain cannabinoid receptors known to disrupt coordinated activity in hippocampus, to investigate the roles of network oscillations during hippocampal and medial prefrontal cortical (mPFC) interactions in rats. During...
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THE INFLUENCE OF WATER-LAND RELATIONS ON THE LANDSCAPE AND ARCHITECTURE OF THE VISTULA DELTA (POLAND)
PublicationThe Vistula Delta is unique region of water domination. In this part of Europe, historic rural assumptions have been developing since the 12th century. Practically, it can be said that most of the systems were related to the coexistence of the human and the water element. Relations of water and land, developed specific types of villages such as a water-based village. Water landscape; polders, canals, dikes and rivers, hydro-technical...
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Using Isolation Forest and Alternative Data Products to Overcome Ground Truth Data Scarcity for Improved Deep Learning-based Agricultural Land Use Classification Models
PublicationHigh-quality labelled datasets represent a cornerstone in the development of deep learning models for land use classification. The high cost of data collection, the inherent errors introduced during data mapping efforts, the lack of local knowledge, and the spatial variability of the data hinder the development of accurate and spatially-transferable deep learning models in the context of agriculture. In this paper, we investigate...
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THE 3D MODEL OF WATER SUPPLY NETWORK WITH APPLICATION OF THE ELEVATION DATA
Publication3D visualization is a key element of research and analysis and as the source used by experts in various fields e.g.: experts from water and sewage systems. The aim of this study was to visualize in three-dimensional space model of water supply network with relief. The path of technological development of GESUT data (Geodezyjna Ewidencja Sieci Uzbrojenia Terenu – geodetic records of public utilities) for water supply and measurement...
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Project-Based Learning as a Method for Interdisciplinary Adaptation to Climate Change—Reda Valley Case Study
PublicationThe challenges of the global labour market require university authorities to extend traditional forms of education into more innovative and effective solutions. Project-based learning (PjBL) is one of highly effective methods for acquiring knowledge and teaching “soft” skills to future employees. This article describes an experimental use of PjBL at a university with a long history of teaching based on traditional methods—the Gdansk...
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Spatial variability of throughfall in a stand of Scots pine (Pinus sylvestris L.) with deciduous admixture as influenced by canopy cover and stem distance
PublicationVegetation cover affects the amount of precipitation, its chemical composition and its spatial distribution, and this may have implications for the distribution of water, nutrients and contaminants in the subsurface soil layer. The aim of this study was a detailed diagnosis of the spatio-temporal variability in the amount of throughfall (TF) and its chemical components in a 72-year-old pine stand with an admixture of oak and birch....
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Impact of Climate Change on Water Sources and River‐Floodplain Mixing in the Natural Wetland Floodplain of Biebrza River
PublicationThe origins of river and floodplain waters (groundwater, rainfall, and snowmelt) and their extent during overbank flow events strongly impact ecological processes such as denitrification and vegetation development. However, the long-term sensitivity of floodplain water signatures to climate change remains elusive. We examined how the integrated hydrological model HydroGeoSphere and the Hydraulic Mixing-Cell method could help us...
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METHODS OF TEACHING SPATIAL AND URBAN PLANNING AT GEODESY AND CARTOGRAPHY
PublicationSpatial and town planning is a complex process caused by the interaction between natural and social systems at different temporal and spatial scales. That is the reason, why it is difficult to introduce this subject to students studying disciplines other than spatial or urban planning. The main problem is to define goals, the scope and expected educational effects. The second step is to choose the appropriate teaching and assessment...
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Evidence for consolidation of neuronal assemblies after seizures in humans
PublicationThe establishment of memories involves reactivation of waking neuronal activity patterns and strengthening of associated neural circuits during slow-wave sleep (SWS), a process known as "cellular consolidation" (Dudai and Morris, 2013). Reactivation of neural activity patterns during waking behaviors that occurs on a timescale of seconds to minutes is thought to constitute memory recall (O'Keefe and Nadel, 1978), whereas consolidation...
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Machine Learning-Based Wetland Vulnerability Assessment in the Sindh Province Ramsar Site Using Remote Sensing Data
PublicationWetlands provide vital ecological and socioeconomic services but face escalating pressures worldwide. This study undertakes an integrated spatiotemporal assessment of the multifaceted vulnerabilities shaping Khinjhir Lake, an ecologically significant wetland ecosystem in Pakistan, using advanced geospatial and machine learning techniques. Multi-temporal optical remote sensing data from 2000 to 2020 was analyzed through spectral...
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MIASTO PORTOWE – STRUKTURA, WYZWANIA FUNKCJONALNE I MODELE ROZWOJU
PublicationPort cities are having different spatial structure than those located inlands. As a result of their seaside location, they face specific administrative and functional problems on a daily basis. In the economic and settlement structure of the country, they usually play the role of a "gate" through which streams of cargo are distributed further over the whole hinterland. It is the transport and logistics function of port cities,...
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Evolution of Edges and Porosity of Urban Blue Spaces: A Case Study of Gdańsk
PublicationCurrent waterfront studies focus mainly on a land-based perspective, failing to include the water side. Water is, however, not just a resource for port and industrial purposes and an edge to the waterfront; it is also a feature of the waterfront and the complex relation between water and city. Thus, the article suggests that water-land edges need to be re-contextualised, taking into consideration also their shape, functionality,...
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Novel Diazocrowns with Pyrrole Residue as Lead(II) Colorimetric Probes
PublicationNovel 18- and 23-membered diazomacrocycles were obtained with satisfactory yields by diazocoupling of aromatic diamines with pyrrole in reactions carried under high dilution conditions. X-ray structure of macrocycle bearing five carbon atoms linkage was determined and described. Compounds were characterized as chromogenic heavy metal ions receptors. Selective color and spectral response for lead(II) was found in acetonitrile and...
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MSP for port areas – To what extent should we interfere with governance of ports’ waters? Case study of Polish seaports
PublicationThe EU MSP Directive imposed the requirement to develop plans for all water areas under the jurisdiction of an EU country by the end of March 2021. Poland is the only country in the Baltic Sea Region whose maritime administration has decided to elaborate detailed maritime spatial plans for port waters. The aim of the paper is to draw conclusions from the work carried out so far on the MSP for Polish port water areas. For this purpose,...
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Graphical interface adaption for children to explain astronomy proportions and distances
PublicationMobile Science Center is a Polish project that seeks to bring astronomy knowledge to wider social groups through various applications. In its development it is necessary to design a graphical interface that explains a concept that is difficult to assimilate such as spatial proportions and distances. This paper develops a framework to create graphical representations that explain this learning to the target audience of children....
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Influence of water salinity on corrosion risk - the case of the southern Baltic Sea coast.
PublicationWater corrosivity in Gdansk Bay, Poland, the southern part of the Baltic Sea, was investigated. The analysed region is heavily industrialized, and the coastline is very diverse. Twenty-seven test points along the coastline were selected. Water parameters such as salinity, total dissolved solids content, resistivity, conductivity, oxygenation, pH and corrosion rate were determined. The results of the investigation are presented....
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Virtual reality tools in teaching the conservation and history of Polish architecture
PublicationVirtual reality and its impact on teaching conservation and architectural history is the subject of this article. During the COVID-19 crisis in 2020, the education of students of architecture was transferred by Gdańsk University of Technology (GUT), Gdańsk, Poland, to distance learning. This method has provided academics an opportunity to examine the impact of virtual reality and remote education on architectural history and conservation....
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The importance of the shape of the protein–water interface of a kinesin motor domain for dynamics of the surface atoms of the protein
PublicationA single kinesin motor domain immersed in water has been investigated using molecular dynamics. It has been found that local properties of water in the solvation shell change along with the nature of the neighboring protein surface. However, a detailed analysis leads to the conclusion that the geometrical features of hydrogen bonds and overall structure of kinesin hydration water are not very different from bulk water. The local...
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The importance of the shape of the protein-water interface of a kinesin motor domain for dynamics of the surface atoms of the protein
PublicationSingle kinesin motor domain immersed in water has been investigated using molecular dynamics. It has been found that local properties of water in solvation shell change along with the nature of neighboring protein surface. However, a detailed analysis leads to the conclusion that the geometrical features of hydrogen bonds and overall structure of kinesin hydration water is not very different from bulk water. The local values of...
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Impact of Visual Image Quality on Lymphocyte Detection Using YOLOv5 and RetinaNet Algorithms
PublicationLymphocytes, a type of leukocytes, play a vital role in the immune system. The precise quantification, spatial arrangement and phenotypic characterization of lymphocytes within haematological or histopathological images can serve as a diagnostic indicator of a particular lesion. Artificial neural networks, employed for the detection of lymphocytes, not only can provide support to the work of histopathologists but also enable better...
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Analysis of the Capability of Deep Learning Algorithms for EEG-based Brain-Computer Interface Implementation
PublicationMachine learning models have received significant attention for their exceptional performance in classifying electroencephalography (EEG) data. They have proven to be highly effective in extracting intricate patterns and features from the raw signal data, thereby contributing to their success in EEG classification tasks. In this study, we explore the possibilities of utilizing contemporary machine learning algorithms in decoding...
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Integrated acoustical-optical system for inventory of hydrotechnical objects
PublicationThe knowledge of the location, shape and other characteristics of spatial objects in the coastal areas has a significant impact on the functioning of ports, shipyards, and other waterinfrastructure facilities, both offshore and inland. Therefore, measurements of the underwater part of the waterside zone are taken, which means the bottom of the water and other underwater objects (e.g. breakwaters, docks, etc.), and objects above...
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Container port expansion towards the sea in the context of maritime spatial planning
PublicationThe growth of ships causes a significant increase in demand for new port surfaces and demands for the depths of water bodies in the ports. Due to technological changes in the transshipment and development pressure ports lacks space and they move towards the sea with their activities. The paper discusses the reasons for the phenomenon of expansion of ports towards the sea and its effects on maritime spatial planning.
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Data-driven models for fault detection using kernel pca:a water distribution system case study
PublicationKernel Principal Component Analysis (KPCA), an example of machine learning, can be considered a non-linear extension of the PCA method. While various applications of KPCA are known, this paper explores the possibility to use it for building a data-driven model of a non-linear system-the water distribution system of the Chojnice town (Poland). This model is utilised for fault detection with the emphasis on water leakage detection....
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Multimedia polysensory integration training system dedicated to children with educational difficulties
PublicationThis paper aims at presenting a multimedia system providing polysensory train- ing for pupils with educational difficulties. The particularly interesting aspect of the system lies in the sonic interaction with image projection in which sounds generated lead to stim- ulation of a particular part of the human brain. The system architecture, video processing methods, therapeutic exercises and guidelines for children’s interaction...
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Two-particle entropy and structural ordering in liquid water
PublicationEntropies of simple point charge (SPC) water were calculated over the temperature range 278-363 K using the two-particle correlation function approximation. Then, the total two-particle contribution to the entropy of the system was divided into three parts, which we call translational, configurational, and orientational. The configurational term describes the contribution to entropy, which originates from spatial distribution of...
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Bridging theory and practice in postgraduate education on development and planning: Gdynia Urban Summer Schools 2016-2018
PublicationIn this article, the authors discuss results achieved by the Gdynia Urban Summer School (GUSS) organised annually (between 2016 and 2018) in Gdynia, Poland. The GUSS was meant for young practitioners from various professions such as urban and regional planning, urban design, architecture, civil engineering and transport planning. The objective was to give workshop participantspractical interdisciplinary...
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Environmental aspects of shale gas recovery in Baltic Basin
PublicationFactors limiting shale gas exploration and exploitation in Pomorskie Voivodeship are presented. In particular, ground and surface water availability and land/community impact is discussed. Production from unconventional reservoirs requires proper well completion through hydraulic fracturing, hence voluminous streams of water are needed – in total 8000 to 20000 m3 per 1000 m of borehole length. 17 major groundwater basins were characterized....
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Long-term Hindcast Simulation of Currents, Sea Level, Water Temperature and Salinity in the Baltic Sea
PublicationThis dataset contains the results of numerical modelling of currents, sea level, water temperature and salinity over a period of 50 years (1958–2007) in the Baltic Sea. A long-term hindcast simulation was performed using a three-dimensional hydrodynamic model (PM3D) based on the Princeton Ocean Model (POM). The spatial resolution was 3 nautical miles, i.e. about 5.5 km. Currents, water temperature, and salinity were recorded...
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Identification of the Contamination Source Location in the Drinking Water Distribution System Based on the Neural Network Classifier
PublicationThe contamination ingression to the Water Distribution System (WDS) may have a major impact on the drinking water consumers health. In the case of the WDS contamination the data from the water quality sensors may be efficiently used for the appropriate disaster management. In this paper the methodology based on the Learning Vector Quantization (LVQ) neural network classifier for the identification of the contamination source location...
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Visualizing spatially decomposed intermolecular correlations in the infrared spectra of aprotic liquids
PublicationInfrared (IR) spectroscopy is commonly used to study intermolecular interactions in the liquid phase, including solvation phenomena. On the other hand, ab initio molecular dynamics (AIMD) simulations offer the possibility to obtain IR spectra from first principles. Surpassing the experiment, AIMD simulations can deliver additional information on the spatial intermolecular correlations underlying the IR spectrum of the liquid. Although...
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Sensitivity of the Baltic Sea level prediction to spatial model resolution
Publicationhe three-dimensional hydrodynamic model of the Baltic Sea (M3D) and...
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Structural Adaptive, Self-Separating Material for Removing Ibuprofen from Waters and Sewage
Publication-cyclodextrin nanosponge (CDM) was used for the adsorption of ibuprofen (IBU) from water and sewage. The obtained material was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), Brunauer–Emmett–Teller (BET), Barrett– Joyner–Halenda (BJH), Harkins and Jura t-Plot, zeta potential, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and elementary analysis (EA)....
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Optimising approach to designing kernel PCA model for diagnosis purposes with and without a priori known data reflecting faulty states
PublicationFault detection plays an important role in advanced control of complex dynamic systems since precise information about system condition enables efficient control. Data driven methods of fault detection give the chance to monitor the plant state purely based on gathered measurements. However, they especially nonlinear, still suffer from a lack of efficient and effective learning methods. In this paper we propose the two stages learning...
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Hydrological responses to large-scale changes in land cover of river watershed: Review
PublicationDespite many studies on the hydrological responses to forest cover changes in micro and mesoscale watersheds, the hydrological responses to forest cover alterations and associated mechanisms through the large spatial scale of the river watershed have not been comprehensively perceived. This paper thus reviews a wide range of available scientific evidence concerning the impacts exerted by the forest removal on precipitation, water...
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Kształtowanie nowej tożsamości regionalnej w przestrzeniach dominacji wody na Żuławach Delty Wisły
PublicationCelem naukowym rozprawy jest sformułowanie kierunku zagospodarowania przestrzennego regionu Żuław Delty Wisły. To unikatowy w skali europejskiej region, który jest fenomenem cywilizacji hydraulicznej i dominacji wody. Proces polderyzacji, który rozpoczął się już w XIII wieku doprowadził do utworzenia historycznych układów urbanistycznych. W roku 1945 nastąpiło przerwanie ciągłości kulturowej. Współcześnie na obszarze Żuław istnieją...
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Pier of the future- investigation of green and blue strategies as tools for modernization of Gdynia's public waterfront
PublicationBetween rising water levels and global migration to cities, architects and designers need to critically reimagine the relationship between coastal landscapes and public space. Cities are facing entirely new risks and environmental conditions. Resiliency, infrastructure, and ecology are increasingly common terms, reflecting the growing demand to address the spatial and formal challenges faced by cities worldwide. Rethinking boundaries...