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Search results for: MS/MS detection
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Recent advancements in LC‐MS based analysis of biotoxins: Present and future challenges
PublicationThere has been a rising concern regarding the harmful impact of biotoxins, source of origin, and the determination of the specific type of toxin. With numerous reports on their extensive spread, biotoxins pose a critical challenge to figure out their parent groups, metabolites, and concentration. In that aspect, liquid chromatography‐mass spectrometry (LC‐MS) based analysis paves the way for its accurate identification and quantification....
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LC-MS and LC-NMR as Complementary Techniques for the Determination of Pharmaceuticals in Dosage Formulations
PublicationPharmaceuticals contain not only pharmacologically active compounds but also a range of excipients. The danger exists that impurities may also be present in such drugs, which may adversely affect their efficacy and even endanger patient health and life. Monitoring the composition of pharmaceutical products is therefore essential. The trace amounts of such impurities in pharmaceuticals are often identified and determined with liquid...
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Problems of PAH quantification by GC-MS method using isotope-labelled standards.
PublicationChromatografia gazowa w połączeniu ze spektromerią mas (GC-MS) jest obecnie rutynowo stosowaną metodą w analityce środowiskowej do oznaczania śladowych ilości zanieczyszczeń organicznych. Stosowanie detektora mas sprawia, że wygodnym wzorcem wewnętrznym są stabilne izotopowo analogi oznaczanych związków. Związki te są wykorzystywane do śledzenia i kompensacji strat analitów podczas wykonywania określonych operacji związanych z...
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Revealing dynamic changes of the volatile profile of food samples using PTR–MS
PublicationVolatile compounds carry valuable information regarding the properties of foodstuffs. Volatiles emitted from food can be used as, for example, indicators of quality, shelf-life, or authenticity. A better understanding of the multitude of transformations which occur during food processing could facilitate the optimisation of production, increase the desirability of food products, and also their wholesomeness. However, as some of...
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Complementary use of GCxGC–TOF–MS and statistics for differentiation of variety in biosolid samples
PublicationFormation of biosolid cakes, which are one of the main wastes generated in wastewater treatment plants, is connected with emission of many hazardous chemical compounds, including odoriferous ones. To optimize particular processes of biosolid cake processing, it is necessary to assess chemical composition of the gas mixtures containing the compounds released from the cakes. The paper proposes application of two-dimensional gas chromatography...
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PTR-MS and electronic nose application for volatile fraction analysis of cigar tobacco
PublicationCigar consumers attach great importance to the quality of these products. At the same time, cigars are often expensive, so destructive analytical methods of quality control are not being desired. However, it has been found that there are many volatile organic compounds in their headspace. Because of that, proton transfer reaction–mass spectrometry and electronic nose were used to analyse it. The obtained results were used to distinguish...
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Review of the applicability of ionic liquid matrices for the quantification of small molecules by MALDI MS
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Problems of PAH quantification by GC–MS method using isotope-labelled standards
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LC-ESI-MS profiling of Potentilla norvegica and evaluation of its biological activities
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Technology Acceptance of MS Teams Among University Teachers During COVID-19
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Profile and Content of Phenolic Compounds in Leaves, Flowers, Roots, and Stalks of Sanguisorba officinalis L. Determined with the LC-DAD-ESI-QTOF-MS/MS Analysis and Their In Vitro Antioxidant, Antidiabetic, Antiproliferative Potency
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O badaniach i analizach mostów tymczasowych typu Bailey - MS 22-80
PublicationPrzedstawiono sposoby modelowania oraz wyniki badań in situ konstrukcji mostów tymczasowych typu Bailey - MS 22-80. Sformuowano wnioski dotyczące rzeczywistego zachowania się tego rodzaju konstrukcji oraz zasad modelowania w celu jednoznacznego określenia pracy i wytężenia ustroju.
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Mosty tymczasowe typu BAILEY - MS 22-80 w świetle badań in SITU
PublicationW pracy przedstawiono i omówiono zakres badań, wybrane modele obliczeniowe, wyniki analiz teoretycznych i badań odbiorowych (próbnych obciążeń o rozszerzonym zakresie), oraz spostrzeżenia dotyczące zachowania się konstrukcji na przykładzie kilku badanych obiektów mostów tymczasowych typu bailey - MS 22-80.
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Determination of odour concentration by TD-GC×GC–TOF-MS and field olfactometry techniques
PublicationField olfactometry is one of the sensory techniques used to determine odour concentration, in atmospheric air, directly in emission sources. A two-dimensional gas chromatography with time of flight mass spectrometer (GC×GC–TOF-MS) allows performing the chemical characterization of various groups of chemical compounds, even in complex mixtures. Application of these techniques enabled determination of odour concentration level in...
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Nano-structured Pt embedded in the acidic salts of heteropolymolybdate matrices: MS XAFS study
PublicationMultiple-scattering extended X-ray absorption fine structure (MS EXAFS) study combined with TEM and XRD analysis of a novel Pt-based catalyst operating at low temperature fuel cells (FCs) is presented. Innovation in the case of the considered catalyst resides in the use of a porous inorganic matrix of acidic heteropolymolybdate salts as a catalyst support. Obtained results show the relation between the matrix composition and the...
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Identification of L. monocytogenes and atypical isolates by MALDI TOF MS.
Open Research DataThe data represent the results of research within the scientific activity Miniatura 5 entitled "Characterization of atypical Listeria monocytogenes strains isolated from the food production environment financed by the National Science Center (no. DEC 2021/05/X/NZ9/00143). The aim of this part of the project was (i) to determine the peptide composition...
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Novel materials and approaches for solid-phase (micro) extraction in LC-MS-based metabolomics
PublicationMetabolomics offers a unique approach to study biological systems. Liquid chromatography coupled to mass spectrometry serves as a powerful analytical tool to analyze complex mixtures of metabolites. However, successful metabolomic analysis relies on sample preparation. While untargeted analysis traditionally favors nonselective procedures like liquid-liquid extraction (LLE), these methods can compromise analytical performance due...
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Nano-structured Pt embedded in acidic salts of heteropolymolybdate matrices: MS EXAFS study
PublicationA structural study of Pt nano-catalysts is presented in the paper. The innovation in the case of the considered catalytic materials resides in the use a meso-microporous inorganic matrix of heteropolyacid salt of composition X2.5H0.5YMo12O40 where X = Rb, Cs and Y = P, Si as a catalyst support. Metallic nanoparticles were created by platinum ions reduction in a hot H2/Argon stream and were mainly located into matrix pores. As the...
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Chiral analysis of chloro intermediates of methylamphetamine by one-dimensional and multidementional NMR and GC/MS
PublicationImpurity profiling and classification of abused drugs using chiral analytical techniques is of particular interest and importance because of the additional information obtained fromthis approach. When these methods are applied to the synthesis of illicitly used substances, they can supply valuable information about the conditions/chemicals used in the synthesis. We have applied GC and NMR methods to the study of intermediates found...
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The chromatographic analysis of extracts from poplar (Populus sp.) - Laying program GC-MS
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Endogenous oxidative DNA base modifications analysed with repair enzymes and GC/MS technique
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A Robust Method for Sample Preparation of Gastrointestinal Stromal Tumour for LC/MS Untargeted Metabolomics
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Analysis of urinary nucleosides as potential cancer markers determined using LC–MS technique
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New approach in determination of urinary diagnostic markers for prostate cancer by MALDI-TOF/MS
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Identification of antioxidant polyphenolics from Jasione montana based on a preliminary LC-MS profiling
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Identyfikacja i diagnostyka procesu oczyszczania ścieków przy użyciu metody MS-PCA
PublicationPołączenie algorytmu PCA z dekompozycją falkową pozwala na wiarygodną identyfikację i diagnostykę procesu z wieloma skalami czasu. Niniejszy artykuł pokazuje jak przy pomocy wspomianego narzedzia określić stan pracy obiektu oraz odpowiednio szybko wykryć uszkodzenia (np. czujników pomiarowych) lub stany awaryjne obiektu jakim jest oczyszczalnia ścieków. Przedstawiony jest przykład detekcji błędów pomiarowych (stężenie tlenu w komorze...
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Main strategies, analytical trends and challenges in LC-MS and ambient mass spectrometry-based metabolomics
PublicationA plethora of analytical LC-MS-based methods have been successfully applied to analyses of complex samples of various origin for metabolomics investigations. Over the last ten years, the substantial evolution of ambient mass spectrometry (AMS) techniques has highlighted their tremendous potential in metabolomic studies due to the minimal sample pretreatment requirement and the ability to analyse samples in their native state. This...
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3-Monochloropropane-1,2-diol in Infant Foods and Human Breast Milk: Determination by GC-MS
Publication3-Monochloropropane-1,2-diol is one of the food borne contaminants called chloropropanols. Over the last decade plenty of analytical methods was developed in order to determine 3-monochloropropane-1,2-diol in its free and bound form in various foodstuffs with the use of GC-FID, GC-ECD, LC-TOFMS and finally GC-MS, which is now widely used in laboratories. The aim of this research was the determination of 3-monochloropropane--1,2-diol...
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The dispersive micro-solid phase extraction method for MS-based lipidomics of human breast milk*
PublicationA simple and rapid microextraction method ensuring high lipidome coverage was developed for liquid chromatography mass spectrometry (LC-MS)-based lipidomics of human breast milk. The dispersive microsolid phase extraction (D-µ-SPE) technique, coupled with the design of experiment (DoE) method, enabled the study of the influence of several conditions (desorption solvent, stationary phase ratio, and sorption and desorption time)...
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Validated GC–MS method for determination of bisphenol a and its five analogues in dietary and nutritional supplements
PublicationBisphenol A (BPA) and its analogues showing structural and functional similarity to BPA are commonly applied in various industrial applications and thus are becoming ubiquitous in the environment. At the same time there is increasing scientific evidence that exposure to these chemicals may lead to adverse health effects in human and wildlife. In recent years dietary and nutritional supplements dedicated for athletes have become...
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Determining the true content of quercetin and its derivatives in plants employing SSDM and LC–MS analysis
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GC-MS-based untargeted metabolomics of plasma and urine to evaluate metabolic changes in prostate cancer
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settingsOrder Article Reprints This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle Investigation of the Frying Fume Composition During Deep Frying of Tempeh Using GC-MS and PTR-MS
PublicationThis study employed proton transfer reaction mass spectrometry (PTR-MS) and gas chromatography–mass spectrometry (GC-MS) to identify and monitor volatile organic compounds (VOCs) in frying fumes generated during the deep frying of tempeh. The research aimed to assess the impact of frying conditions, including frying temperature, oil type, and repeated use cycles, on the formation of thermal decomposition products. A total of 78...
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Ekspertyza techniczna dot. stref zakotwień kabli sprężających – obiekt MS-6 w ciągu S7
PublicationOpracowanie zawiera wyniki badań i symylacji MES na temat stref zakotwień wewnętrznych kabli sprężenia podłużnego oraz wskazuje na przyczyny przemieszczenia biernych bloków kotwiących wewnętrznych kabli sprężenia podłużnego przęsła 7-8 mostu MS-6 zlokalizowanego w drogi krajowej S-7 na odcinku Miłomłyn – Olsztynek.
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The application of isotopically labeled analogues for the determination of small organic compounds by GC/MS with selected ion monitoring
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Method development and validation for optimized separation of the major polyphenolics in propolis extracts using GC-MS method
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Identification of odorant characters using GC-MS/O in biosolids emissions from aerobic and anaerobic stabilisation
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GC-MS analysis, antidiabetic and antioxidant activity of methanolic extract of pluteus cervinus: an in vitro and in silico approach
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Phyloproteomic study by MALDI-TOF MS in view of intraspecies variation in a significant homogenous phytopathogen Dickeya solani
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Characteristics of Cucumis metuliferus, Actinidia deliciosa and Musa paradisica fragrance profiles using a comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection (GC×GC-TOF MS)
PublicationComprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection (GC×GC-TOF-MS) is a modern analytical technique used in many fields. This technique enables an effective separation of volatile chemical compounds [1]. In recent years, the topic of healthy food and healthy living has become very popular. For this reason, more and more scientific publications related to the analysis of food products...
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The profiles and spectrum of aqua solution of tannic acid by HPLC-DAD-MS analysis.
Open Research DataThe profiling of tannic acid is determined by examining the content and proportion / ratio of gallotannins [Aras et al. 2016, Clifford et al. 2007, Gauri et al. 2012, Nishizawa et al. 1982]. In order to check the ion mass distribution (TIC) in an aqueous solution of commercial tannic acid, a direct sample injection (TA) was performed into the mass spectrometer....
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Flowers and Leaves Extracts of Stachys palustris L. Exhibit Stronger Anti-Proliferative, Antioxidant, Anti-Diabetic, and Anti-Obesity Potencies than Stems and Roots Due to More Phenolic Compounds as Revealed by UPLC-PDA-ESI-TQD-MS/MS
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Fast-SEC coupled to ICP-MS for selected metal determination and its stability over time in polish wine
PublicationMetal ions contribute to the wine browning (as reaction catalysts), turbidity (in complexes), and astringency (due to inter- action with tannins). Being aware that bioavailability and metabolism of metal ions in the human body are strictly related with their concentration and the form they occur it is important to monitor not only the total content of metals but also their speciation. Thus, we can obtain more information about...
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Ekspertyza dotycząca przyczyn pęknięcia rurociągu 8”-096-P1059, zamówienie nr WU/0402/2020/MS
PublicationWykonano badania nieniszczące i niszczących próbek materiału rurociągu wraz z przygotowaniem próbek do badań z materiału rodzimego.
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Impact of Cluster Zone Leaf Removal on Grapes cv. Regent Polyphenol Content by the UPLC-PDA/MS Method
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Direct injection liquid chromatography-mass spectrometry (DI-LC-MS) analysis for rapid lipidomic profiling of extracellular vesicles
PublicationExtracellular vesicles (EVs) are small, spherical particles produced by eukaryotic and prokaryotic cells, surrounded by a bilayer membrane and carrying various bioactive molecules, such as proteins, surface receptors, membrane and soluble proteins, lipids, and nucleic acids. EVs are of substantial interest because of their important roles in cell communication, epigenetic regulation and possible application in disease diagnosis...
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MRM–MS of marker peptides and their abundance as a tool for authentication of meat species and meat cuts in single-cut meat products
PublicationThe abundance of protein markers in different types of meat cuts was explored in the context of authentication of raw meat (pork, beef and chicken) and processed meat products. Peptides originating from myoglobin (Mb) and myosin (My) were analyzed using multiple reaction monitoring mass spectrometry (MRM–MS). Analytical protocol was optimized for good repeatability (CV < 10%) and high sensitivity. The MS signal intensity of Mb...
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Elucidation of transformation pathway of ketoprofen, ibuprofen, and furosemide in surface water and their occurrence in the aqueous environment using UHPLC-QTOF-MS
PublicationThe identification and determination of transformation products (TPs) of pharmaceuticals is essential nowadays, in order to track their fate in the aqueous environment and, thus, to estimate the actual pollution. However, this is a challenging task due to the necessity to apply high-resolution instruments enable to detect known and unknown compounds. This work presents the use of liquid chromatography quadrupole time-of-flight...
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Metodyka rozdzielania i oznaczania lotnych inhibitorów fermentacji w brzeczkach fermentacyjnych ciemnej fermentacji, techniką GC-MS
PublicationW pracy przedstawiono opracowaną w wyniku badań metodykę identyfikacji i oznaczania inhibitorów fermentacji w brzeczkach fermentacji ciemnej z biomasy ligno-celulozowej, z wykorzystaniem ekstrakcji ciecz-ciecz w sprzężeniu z chromatografią gazową ze spektrometrem mas (LLE-GC-MS). W ramach badań dokonano doboru korzystnych warunków ekstrakcji ciecz-ciecz, w tym: pH, objętości rozpuszczalnika ekstrakcyjnego, czasu ekstrakcji oraz warunków...
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Verification of the homogeneity of the matrix/analyte mixture on sample plate using MALDI-MS technique and new ionic liquid matrices
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