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Search results for: G.B. Bonifacio
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Geomatyka B Ćwiczenia_2023
e-Learning Courses -
Wstępne badania technologii spawania złączy narożnych ze stali niskoweglowej i nierdzewnej o grubości g=6mm i g=10mm
PublicationCelem pracy był dobór parametrów spawania dla spoin narożnych o grubości 6mm i 10mm próbek wykonanych ze stali niskowęglowej S355 i stali nierdzewnej - typu 304 (X6CrNI18-10). Złącza były spawane laserowo, jednostronnie z pełnym przetopem a powierzchnie lica i grani zapewniają uzyskanie szczelności przylegającego elementu uszczelniającego. Próbki zostały dostarczone przez Zleceniodawcę. Próby zostały przeprowadzone na stanowisku...
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Novel primosomal protein B from Clostridium pastuerianum
PublicationPriB is a primosomal protein that catalyzes DNA replication in Procaryota. The replication pathway starts with PriA protein - the initiator protein that binds to a DNA replication fork, unwinds double-stranded DNA and role of PriB is to stabilize PriA on the DNA. However there are many biochemical differences in replication mechanism in bacteria and only some of them use PriB proteins. A few of PriB proteins were published and...
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Novel primosomal protein B from Clostridium pasteurianum
PublicationPriB is a primosomal protein that catalyzes DNA replication in Procaryota. The replication pathway starts with PriA protein - the initiator protein that binds to a DNA replication fork, unwinds double-stranded DNA and role of PriB is to stabilize PriA on the DNA. However there are many biochemical differences in replication mechanism in bacteria and only some of them use PriB proteins. A few of PriB proteins were published and...
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Interaction of amphotericin B with phospholipids in the model membrane - molecular dynamics study.
PublicationAmfoterycyna B jest antybiotykiem używanym w leczeniu układowych infekcji grzybowych. Jej mechanizm działania polega na tworzeniu kanałów wewnątrz błon lipidowych. W przedstawianej pracy publikowane są wyniki symulacji przeprowadzonej dynamiką molekularną monomerycznej i dimerycznej formy antybiotyku wewnątrz błony lipidowej zbudowanej z cząsteczek DMPC. Wyniki te wskazują, że powinowactwo cząsteczek amfoterycyny wewnątrz dimeru...
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Wpływ domieszkowania w podsieci B wysokotemperaturowego przewodnika protonowego LaNbO4
PublicationW artykule przeprowadzono analizę wpływu domieszkowania w podsieci B niobanu lantanu korzystając z opublikowanych wyników zespołów badawczych z całego świata. Przeanalizowano wpływ domieszkowania pod kątem domieszek akceptorowych i izowalentnych. Przeanalizowano wpływ zastosowania wielu różnych domieszek tj. Ga, Ge, Si, Ti i Mn na strukturę fazową i przewodność elektryczną materiału. Domieszkowanie akceptorowe w podsieci B pozwala...
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Molecular modelling of membrane activity of amphotericin B, a polyene macrolide antifungal antibiotic
PublicationPraca dotyczy różnego typu modelowań molekularnych cząsteczki przeciwgrzybowego antybiotyku (amfoterycyny B). Praca przeglądowa obejmuje opis badań nad właściwościami molekularnymi samej cząsteczki antybiotyku, jej oddziaływań z powierzchnią błony oraz struktur kanałowych jakie tworzą cząsteczki amfoterycyny wewnątrz błony lipidowej.
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Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
PublicationBecause of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DEAH-box helicase, which participates in gene expression and replication by recognizing and unwinding parallel G4s. Here, we studied the molecular basis for the high affinity and specificity of DHX36 for parallel-type...
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Why do G-quadruplexes dimerize through the 5’-ends? Driving forces for G4 DNA dimerization examined in atomic detail
PublicationG-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid sequences and shown to exist in living cells where they participate in regulation of gene expression and chromosome maintenance. G-quadruplexes with solvent-exposed guanine tetrads show the tendency to associate together through cofacial stacking, which may be important for packaging of G4-forming sequences and allows for the design of higher-order...
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Degradation of tetracycline antibiotic utilizing light driven-activated oxone in the presence of g-C3N4/ZnFe LDH binary heterojunction nanocomposite
PublicationIn the present study, a binary heterojunction nanocomposite composed of graphitic carbon nitride (g-C3N4) and Zn/Fe-contained layered double hydroxide (ZnFe LDH) was employed as heterogeneous catalyst for the decomposition of tetracycline (TC) antibiotic utilizing Oxone and UV light irradiation. The sole use of g-C3N4/ZnFe LDH as adsorbent led to the negligible elimination of TC. In addition, the sole use of Oxone or UV (photolysis)...
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Performance Analysis of Machine Learning Methods with Class Imbalance Problem in Android Malware Detection
PublicationDue to the exponential rise of mobile technology, a slew of new mobile security concerns has surfaced recently. To address the hazards connected with malware, many approaches have been developed. Signature-based detection is the most widely used approach for detecting Android malware. This approach has the disadvantage of being unable to identify unknown malware. As a result of this issue, machine learning (ML) for detecting malware...
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Investigation of interaction between xanthene dye rhodamine B and metagenomic-derivated methylthioadenosine phosphorylase RSFP
PublicationIn the previous study we found that the expression of the metagenomic - derived methylthioadenosine phosphorylase gene (rsfp) in E. coli cells and the presence of rhodamine B in the growth medium were crucial for the pink fluorescence of one E. coli colony from Antarctic soil metagenomic library (Cieśliński et al., 2009). In this study, rsfp gene expression was induced by an arabinose promoter in an LMG194 E. coli strain and the...
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Thermal properties of terpoly(ester-b-ether-b-amide)s with aliphatic ester blocks
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Synthesis of disubstituted 1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids derivatives
Publication1,3,4,9-tetrahydropyrano[3,4-b ]indole-1-acetic acid derivatives are of interest for pharmaceutical research as a core structure for synthesis of biological active substance - Etodolac (selective Cyclooxygenase-2 inhibitor, which belongs to the Non-steroidal Anti-inflammatory Drug, NSAID, that shows a clin-ically effective analgesic and anti-inflammatory activity). Here the way of synthesis of two 1,3,4,9-tetrahydropyrano[3,4-b...
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Induction Assisted Hybrid Friction Stir Welding of Dissimilar Materials AA5052 Aluminium Alloy and X12Cr13 Stainless Steel
PublicationThis research aimed to study the induction in-situ heated hybrid friction stir welding (IAFSW) method to join AA5052 aluminium alloy with X12Cr13 stainless steel (SS) to enhance joint strength. The potency of this method on the mechanical properties and microstructural characterizations were also investigated. The results show that the transverse tensile strength gained was 94% of the AA5052 base metal that is 229.5 MPa. This superior...
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Real estate investment trusts in Turkey: Structure, analysis, and strategy
PublicationPurpose-Aim of this study is to make the determinations related to the problems mentioned in the REIT sector in Turkey, to offer a solution for this issue, and to ensure the classification in the sector by adhering to the financial data of the REITsMethodology-Financial data set of the REITs was firstly standardized by using median instead of mean. Then, the scoring was performed according to defined coefficients....
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JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS
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Interactions of amphotericin B derivative of low toxicity with biological membrane components - the Langmuir monolayer approach
PublicationMetodą monowarstw Langmuira zbadano naturę oddziaływań nowej pochodnej antybiotyku przeciwgrzybowego amfoterycyny B o niskiej toksyczności, tj. estru metylowego N-metylo-N-D-fruktopiranozyloamfoterycyny B (MF-AME)z komponentami błon biologicznych: ergosterolem, występującym w komórkach grzybowych i cholesterolem występującym w komórkach zwierzęcych oraz z modelowym fosfolipidem DPPC i na tej podstawie stwierdzono, że zróżnicowanie...
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Cathepsin G activity lowers plasma LDL and reduces atherosclerosis
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Influence of a lipid bilayer on the conformational behavior of amphotericin B derivatives - A molecular dynamics study.
PublicationAmphotericin B (AmB) is an effective but very toxic antifungal antibiotic. In our laboratory a series of AmB derivatives of improved selectivity of action was synthesized and tested. To understand molecular basis of this improvement, comparative conformational studies of amphotericin B and its two more selectivederivatives were carried out in an aqueous solution and in a lipid membrane. These molecular simulation studies revealed...
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Internacjonalizacja działalności badawczo-rozwojowej (B+R) przedsiębiorstw high-tech. Wyniki badań empirycznych
PublicationGłownym celem artykułu jest przedstawienie roli badań i rozwoaju (B+R) w procesie internacjonalizacji przedsiębiorstw high-tech. Artykuł obejmuje przegląd literatury oraz wyniki badań 263 przedsiębiorstw high-tech przeprowadzonych na terytorium Polski. Artykuł powstał w ramach projektu badawczego OPUS 6 pt. Wzorce internacjonalizacji małych i średnich przedsiębiorstw działających w branżach high-tech finansowanego przez Narodowe...
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Krytyczny stosunek ciśnień b w rozumieniu norm ISO 6358 i ISO 6953
PublicationJednym z parametrów służących do opisu właściwości przepływowych elementu pneumatycznego jest krytyczny stosunek ciśnień b, zdefiniowany i wykorzystywany w ISO 6358 oraz ISO 6953. Jednak w myśl metod jego wyznaczania opisanych w ISO 6358 i ISO/DIS 6358 definicja ta wydaje się być inna. W pracy omówiono warunki jakie musi spełniać element pneumatyczny, aby wartość b wyznaczona tymi metodami była zbliżona do wartości definicyjnej....
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Interaction of amphotericin B and its low toxic derivative, N-methyl-N-D-fructosyl amphotericin B methyl ester, with fungal, mammalian and bacterial cells measured by the energy transfer method.
PublicationPochodna amfoterycyny B ( AMB) ester metylowy N-metylo-N-D-fruktozylo amfoterycyny B (MFAME) wykazuje szerokie spektrum i wysoką aktywność przeciwgrzybową wyjściowego amtybiotyku i równocześnie toksyczność mniejszą o dwa rzędy wielkości. Celem tej pracy było ustalenie czy obserwowane różnice między toksycznością pochodnej i wyjściowego antybiotyku wynikają z różnic w powinowactwie do błon komórkowych grzybów i komórek ssakowych....
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Agregacja amfoterycyny B i wybranych pochodnych - chemometryczna analiza widm UV-Vis
PublicationPrezentowane badania miały na celu poznanie procesu agregacji nowej generacji pochodnych polienowego antybiotyku przeciwgrzybowego - amfoterycyny B. Przebieg procesu agregacji w roztworach wodnych o różnym składzie monitorowano przy pomocy absorpcyjnej spektroskopii UV-Vis. Otrzymane zestawy widm analizowano z zastosowaniem zaawansowanych technik chemometrycznych (PCA, NSD), co pozwoliło na określenie liczby, typu i ilości form...
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Molecular modeling of amphotericin B - ergosterol primary complex in water II
PublicationPrezentowane badania dotyczą oddziaływania antybiotyku polienowego anfoterycyny B (AmB) i ergosterolu (ERG) (typowego sterolu błonowego komórek grzybowych) na poziomie molekularnym. W odróżnieniu od badanego poprzednio kompleksu binarnego analizowany obecnie kompleks AnB/ERG/AmB charakteryzuje się zdecydowanie wiekszą stabilnością i wzglednie sztywną, sandwiczową geometrią. Za trwałość i geometrie kompleksu odpowiedzialne są oddziaływania...
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Effect of Chitosan Solution on Low-Cohesive Soil’s Shear Modulus G Determined through Resonant Column and Torsional Shearing Tests
PublicationIn this study the effect of using a biopolymer soil stabilizer on soil stiffness characteristics was investigated. Chitosan is a bio-waste material that is obtained by chemical treatment of chitin (a chemical component of fungi or crustaceans’ shells). Using chitosan solution as a soil stabilizer is based on the assumption that the biopolymer forms temporary bonds with soil particles. What is important is that these bonds are biodegradable,...
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Lattice dynamics of CuAu-orderedCuInSe2
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A study on the interaction of rhodamine B with methylthioadenosine phosphorylase protein sourced from an Antarctic soil metagenomic library.
PublicationThe presented study examines the phenomenon of the fluorescence under UV light excitation (312 nm) of E. coli cells expressing a novel metagenomic-derived putative methylthioadenosine phosphorylase gene, called rsfp, grown on LB agar supplemented with a fluorescent dye rhodamine B. For this purpose, an rsfp gene was cloned and expressed in an LMG194 E. coli strain using an arabinose promoter. The resulting RSFP protein was purified...
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Analiza redystrybucji środków finansowych przeznaczonych na działalność B+R (na przykładzie wybranej uczelni)
PublicationAutor zwraca uwagę na wyjątkowo niskie finansowanie działalności B+R w Polsce na tle innych krajów nowo przyjętych do UE. Przeprowadza analizę redystrybucji tych skromnych środków w skali Polski oraz na przykładzie konkretnej uczelni. Dostrzega dwa charakterystyczne zjawiska, określona jako asymetrie. Pierwsze-dotyczące podziału tych środków między szkoły wyższe, jednostki badawczo-rozwojowe i placówki PAN. Drugie - dotyczące struktury...
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Cahiers du Centre G. Glotz
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E&G Quaternary Science Journal
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TaRh 2 B 2 and NbRh 2 B 2 : Superconductors with a chiral noncentrosymmetric crystal structure
PublicationIt is a fundamental truth in solid compounds that the physical properties follow the symmetry of the crystal structure. Nowhere is the effect of symmetry more pronounced than in the electronic and magnetic properties of materials—even the projection of the bulk crystal symmetry onto different crystal faces is known to have a substantial impact on the surface electronic states. The effect of bulk crystal symmetry on the properties...
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Linear viscoelastic transversely isotropic model based on the spectral decomposition of elasticity tensors
PublicationThe linear viscoelasticity is still a useful model in the engineering for studying the behavior of materials loaded with different loading rates (frequencies). Certain types of materials reveal also an anisotropic behavior: fiber reinforced composites, asphalt concrete mixtures, or wood, to name a few. In general, researchers try to identify experimentally the dependence of engineering constants like: directional Young’s moduli...
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Load introduction to composite columns revisited—Significance of force allocation and shear connection stiffness
PublicationThe AISC 360-16 Specification recommends that the design shear force between parts of a composite column in the load introduction area shall be calculated based on the force allocation at ultimate limit state. Applicability of this straightforward method to the load levels that usually arise in slender composite columns is questionable, as this capacity-based force allocation is only true when the axial force is equal to the plastic...
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Within- and between-person factor structure of the Oldenburg Burnout Inventory: Analysis of a diary study using multilevel confirmatory factor analysis
PublicationThe study examined the factor structure of burnout, as measured with the Oldenburg Burnout Inventory. The participants were 235 employees of a public administration agency who assessed their burnout online for 10 consecutive working days. Two models were tested with multilevel confirmatory factor analysis, assuming the same one or two-factor structure at the within- and between-person levels. Both models showed a reasonable fit...
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The Polish adaptation of the Burnout Assessment Tool (BAT-PL) by W. Schaufeli et al.
PublicationAim. The study aimed to present the Polish version of the Burnout Assessment Tool (BAT-PL) by Schaufeli et al. and to assess its validity and reliability. The tool measures the core symptoms of burnout (BAT-C): exhaustion, mental distance, cognitive and emotional impairment, and its secondary symptoms (BAT-S): psychosomatic complaints and psychological distress. Method. The participants were 255 nursing staff members. The construct...
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Fluctuation-Enhanced Sensing
PublicationFluctuation-enhanced sensing (FES) is an exciting and relatively new research field that promises to extend the range of information that can be extracted from a single sensor. In FES, the stochastic fluctuations of the sensor signal, rather than its average value, are recorded and analyzed. Typical components of such fluctuations are due to interactions at the microscopic level. Proper statistical analysis provides optimum sensory...
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MEMORY EFFECT ANALYSIS USING PIECEWISE CUBIC B-SPLINE OF TIME FRACTIONAL DIFFUSION EQUATION
PublicationThe purpose of this work is to study the memory effect analysis of Caputo–Fabrizio time fractional diffusion equation by means of cubic B-spline functions. The Caputo–Fabrizio interpretation of fractional derivative involves a non-singular kernel that permits to describe some class of material heterogeneities and the effect of memory more effectively. The proposed numerical technique relies on finite difference approach and cubic...
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On the Possibility of the Amphotericin B-Sterol Complex Formation in Cholesterol- and Ergosterol-Containing Lipid Bilayers: A Molecular Dynamics Study
PublicationAmphotericin B (AmB) is a well-known membrane-active antibiotic that has been used to treat systemicfungal infections for more than 45 years. Therapeutic application of AmB is based on the fact that it is moreactive against ergosterol-containing membranes of fungal cells than against mammalian membranes withcholesterol. In this paper, we examine the hypothesis according to which the selectivity of the AmB's membraneaction originates...
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Investing in wine, precious metals and G-7 stock markets – A co-occurrence analysis for price bubbles
PublicationThis paper used the GSADF test to determine the periods defined in this paper as price bubbles in the three markets studied, i.e. the investment wine market, precious metal market and national stock market indices of G-7 countries. The results obtained enabled the calculation of the values of the phi correlation coefficients, which served the research objective of assessing the co-occurrence of price bubbles in the markets analysed....
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Superior synergy of g-C3N4/Cd compounds and Al-MOF-derived nanoporous carbon for photocatalytic hydrogen evolution
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Bias-Dependent Dynamics of Degradation and Recovery in Perovskite Solar Cells
PublicationDegradation of perovskite solar cells (PSCs) is often found to be partially or fully reversible when the cells are allowed to recover in the dark. Unlike the dynamics of degradation, knowledge about the dynamics of PSC cell recovery is very limited. Here, we demonstrate that the PSC recovery strongly depends on the electrical bias conditions during the light-induced degradation and that it can be manipulated by applying an external...
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Repeated Projectile Impact Tests on Multi-Layered FibrousCementitious Composites
PublicationThis research aims to experimentally evaluate the behaviour of multi-layered fibrous cementitious composites withintermediate Glass Fibre Meshes (GFM) under repeated projectile load. The impact load was subjected through a convexedge projectile needle at a low velocity on cylindrical specimens of three-layered fibrous cementitious composites, whichhave two different steel fibre distributions. In series A mixtures, a constant steel...
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A new Apporoach to the Spectral Analysis of Liquid Membrane Oscillators by Gabor Transformation
PublicationOcylatory z membrana ciekłą charakteryzują się nieregularnymi oscylacjami. Widma mocy nie mogą być ustalone za pomocą transformacji Fourier'a do oscylacji niestacjonarnej. Zaprezentowano nowe podejście pozwalające tych przypadkach otrzymać widma mocy. Analizę tę zastosowano do oscylatorów z membraną ciekłą, zawierających kationowy surfaktant. Stwierdzono, że obecnośc róznych dodanych substancji do wodnej fazy akceptorowej wpływa...
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Geomatyka B - Ćwiczenia 2021
e-Learning CoursesObliczenia potencjału elipsoidy ekwipotencjalnej, odchylenie linii pionu, pływu skorupy ziemskiej. Uwzględnianie poprawki terenowej dla obserwacji przyspieszenia siły ciężkości.
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Geomatyka B kopiuj 1
e-Learning Courses -
Influence of narrowband ultraviolet B phototherapy on serum tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in patients with psoriasis
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MicroGal Gravity Measurements with MGS-6 Micro-g LaCoste Gravimeter
PublicationKnowing the exact number of fruit and trees helps growers to make better decisions about how to manage their production in the orchard and prevent plant diseases. The current practice of yield estimation is to manually count fruit or flowers (before harvesting), which is a very time-consuming and costly process. Moreover it’s not practical for large orchards. It also doesn’t allow to make predictions of plant development in a more...
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2022_Elective Design II_S_Hudnik_K_Zyczkowska_There is no Planet B
e-Learning CoursesThere is no Planet B The studio will use practical interventions to explore how climate change is affecting transformations in urban / non-urban space in Gdansk. Through the identification of problems and the importance of reading the consequences in space and architecture, students will learn about the method of opening a critical public debate. Through a variety of topics and actions – micro interventions, they will record their...
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Characterization and Wear Response of Magnetron Sputtered W–B and W–Ti–B Coatings on WC–Co Tools
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