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Search results for: LINKERS, CYTOCOMPATIBILITY
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Effect Of Resveratrol And Quercetin On Telomerase Regulation In Cancer Cells And Their Anti-Cancer Potential
PublicationTelomeres and telomerase are nowadays one on targets for anticancer therapy. Telomerase is expressed in ~90% of human cancer cell lines and tumor specimens, whereas its enzymatic activity is not detectable in most human somatic cells. Was found that some dietary compounds can modulate telomerase activity in cancer cells. This review summarizes the current knowledge about the effects of resveratrol and quercetin on telomerase regulation...
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Romanika Okraszewska dr inż. arch.
PeopleRomanika Okraszewska, Ph.D., Eng. Arch., is an Assistant Professor at the Faculty of Civil and Environmental Engineering of Gdańsk University of Technology (GUT). Graduated from the mathematical and informatical class at the National Education Commission High School in Gdańsk. Graduated from two faculties of Gdańsk University of Technology, Architecture and Urban Planning (2002) and Management and Economics (2004). Participant...
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Zespół Spektroskopii Elektronowej
Research TeamsZespół Spektroskopii Elektronowej specjalizuje się w badaniach procesów oddziaływania różnych form promieniowania z atomami i cząsteczkami znajdującymi się w fazie gazowej. W szczególności badania koncentrują się na opisie mechanizmów wzbudzenia i jonizacji atomów i cząsteczek, dysocjacji biomolekuł poddanych działaniu promieniowania elektromagnetycznego oraz pod wpływem zderzeń z elektronami i kationami. W Zespole prowadzone są...
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Ceria Based Protective Coatings for Steel Interconnects Prepared by Spray Pyrolysis
PublicationStainless steels can be used in solid oxide fuel/electrolysis stacks as interconnects. For successful long term operation they require protective coatings, that lower the corrosion rate and block chemical reactions between the interconnect and adjacent layers of the oxygen or the hydrogen electrode. One of the promising coating materials for the hydrogen side is ceria. Using standard sintering techniques, ceria sinters at around...
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Proteomic and Metabolomic Changes in Psoriasis Preclinical and Clinical Aspects
PublicationSkin diseases such as psoriasis (Ps) and psoriatic arthritis (PsA) are immune-mediated inflammatory diseases. Overlap of autoinflammatory and autoimmune conditions hinders diagnoses and identifying personalized patient treatments due to different psoriasis subtypes and the lack of verified biomarkers. Recently, proteomics and metabolomics have been intensively investigated in a broad range of skin diseases with the main purpose...
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Comparison of thresholding algorithms for automatic overhead line detection procedure
PublicationThe article presents an overview of the thresholding algorithms. It compares the algorithms proposed by Pun, Kittler, Niblack, Huang, Rosenfeld, Remesh, Lloyd, Riddler, Otsu, Yanni, Kapur and Jawahar. Additionally, it was tested how the tuning of the Pun, Jawahar and Niblack methods affects the thresholding efficiency and proposed a combination of the Pun algorithm with a priori algorithm. All presented algorithms have been implemented...
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Cross-linking of epoxy-oligomeric mixtures in the presence of modified phenol-formaldehyde resins
PublicationCross-linking of epoxy oligomeric mixtures consisting of industrial epoxy resin ED-20, oligoetheracrylate TGM-3, peroxide derivative of epoxy resin ED-24 and phenol-formaldehyde oligomer with unsaturated methacrylate fragments or peroxide groups was studied in the presence of polyethylenepolyamine at room temperature and heated to 383, 403 or 423 K for 15, 30, 45, 60 and 75 minute. The influence of mixture composition, temperature...
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Regional implementation of a road safety observatory in Poland
PublicationThe paper outlines the background and goals of the Road Safety Observatory in the Polish region of Warmia and Mazury. While created it was Poland’s first road safety Observatory, both at the regional and central level. Established in line with the methodology proposed in the European project SafetyNet, together with the planned National Road Safety Observatory it will form part of a Europe-wide network of observatories linked with...
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Changing patterns in export of goods versus international competitiveness. A comparative analysis for Central-East European countries in the period 2000-2011.
PublicationThis paper discusses the existing links between changing patterns in the export of goods, broken down by technology-intensity, versus intrenational competitiveness. The study covers nine Central-East European (CEE) economies: Bulgaria, the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania and the Slovak Republic, in the time span 2000-2011. We examine the hypothesis of a strong, positive and statistically significant...
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Low-Profile Interdigitated UHF RFID Tag Antenna for Metallic Objects
PublicationThis article presents a novel miniature interdigitated ultra-high frequency (UHF) radio frequency identification (RFID) tag antenna that can be placed on metallic objects. The tag structure comprises two horizontal strip lines, each loaded with seven identical open stubs, and an integrated circuit (IC) chip connected directly to the feed lines in the middle of the structure. The perfect match to the IC chip’s impedance is realized...
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HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS, Bone marrow - Male, 65 - Tissue image [12030630017633001]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS, Bone marrow - Male, 65 - Tissue image [12030630017634401]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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SWM for porous hierarchical nanocarbons composites
Open Research DataRaw Raman spectra and XRD diffractograms (background subtracted) of 13 among which carbon-derived secondary waste and reference materials.
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Raman spectra and electrochemical data of carbon nanowall with tailored defects
Open Research DataThis dataset comprises of Raman spectra aquired with different excitation laser sources and the electrochemical data of defect-induced carbon nanowall electrodes (CNW).
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Altruists will be altruists, but what about individualists? The role of future time perspective and social value orientation in volunteers’ declarations to continue engagement in three time horizons
PublicationVolunteering involves caring for the outcomes of others and typically long-term orientation so that one can achieve goals that are not always clearly visible in the short term. As with any activity, volunteering attracts people of different social value orientations – some rather individualistic, some rather altruistic. The aim of the study was to find out whether the future time perspective, which promotes thinking about future...
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Advancing sustainable hybrid bitumen systems: A compatibilization solution by functionalized polyolefins for enhanced crumb rubber content in bitumen
PublicationPolymer waste pollution has a profound effect on the environment and, consequently, on the lifestyle of hu- mankind. The massive production and disposal of cross-linked polymers clearly exemplify the challenges of recycling. Increasing efforts are being undertaken to introduce recycled polymers, especially crumb rubber (CR), into asphalt formulations. Due to the rather poor processability and phase separation associated with CR- modified...
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Ground tire rubber thermo-mechanically devulcanized in the presence of waste engine oil as asphalt modifier
PublicationCross-linked elastomers network is main limitation for industrial usage of ground tire rubber (GTR) as asphalts’ and road pavements modifier. GTR was thermo-mechanically devulcanized via extrusion in the presence of waste engine oil (WEO) at temperature ranges from 150 to 280 °C. Combined impact of WEO content and extruder barrel temperature on the change of cross-linked structure of degraded GTR (DTGR) was investigated through...
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Resilient Routing in Communication Networks
PublicationThis important text/reference addresses the latest issues in end-to-end resilient routing in communication networks. The work highlights the main causes of failures of network nodes and links, and presents an overview of resilient routing mechanisms, covering issues related to the Future Internet (FI), wireless mesh networks (WMNs), and vehicular ad-hoc networks (VANETs). For each of these network architectures, a selection of...
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A graphical approach to yield and boundary surfaces of selected hypoplastic constitutive equations
PublicationThe article describes how to identify the boundary and yield surface for hypoplastic constitutive equations proposed by Wu, Gudehus and Bauer. It is shown how to identify and plot the surfaces for any equation in this class. Calculation errors are analyzed characteristic for appleid set of numerical formulas. In the paper there are computer links to the source code prepared in the MATLAB system, based on istructions in the article....
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Le reti della terza Italia.Imprese, calcio, sponsirzzazioni e territorio in Serie B 81982-2006)
PublicationIl capitolo si occupa dei rapporti tra imprese e sponsirzzazioni dei club calcistici italiani della serie B tra il 1982 e il 2006
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Exploring thiophene-2-acetate and thiophene-3-acetate binding modes towards the molecular and supramolecular structures and photoluminescence properties of Pb(ii) polymers
PublicationTo evaluate the impact of the flexible positional isomeric ligands thiophene-2-acetate (2tpacCOO) andthiophene-3-acetate (3tpacCOO) on the construction and self-assembly process of Pb(II) polymers, twonovel compounds, [Pb(2tpacCOO)2(H2O)]n(1) and [Pb(3tpacCOO)2]n(2), were preparedviaanonhydro-thermal method with respect to green chemistry rules. The obtained polymers were fully characterized byelemental analysis, TG/DTG and PXRD,...
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3D Hand Shape Modeling for Automatic Assessing Motor Performance in Parkinson's Disease
PublicationIn this paper a method for hand pattern processing to create a 3D hand model is presented. By applying a complete hand armature to the model obtained, an interpolation of three motor tests for an individual Parkinson's disease patient can be performed. To obtain the 3D hand model the top view of the hand from a web cam is analyzed. The hand contour is examined to find characteristic points that allows for dividing hand image into...
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Implementation of International Standards of Fiscal and Monetary Transparency - Case of Poland
PublicationResearch background: Financial managers, investors, lenders, counterparties and citizens should have useful, reliable, timely, complete, comparable, readable information on fiscal and monetary policy. The actions taken and instruments used by fiscal and monetary authorities have an important impact on economic conditions. Purpose of the article: The aim of the article is to assess Poland's compliance with international standards...
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The influence of the carbon equivalent on the weldability of high-strength low-alloy steel in the water environment
PublicationFrom many years, the high strength low alloy steels are often used for offshore constructions. This constructions, due to the environment in which they work, require more frequent repairs than the constructions from the land. For economic reasons, repairs take place in the underwater conditions, however water significantly decreases the weldability of steel. The paper presents the results of the CTS weldability test for S460ML...
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Degradation of the Concrete Railway Track Bed Located in the Vicinity of the Loading Wharf
PublicationThe following article describes the damages of the concrete railway track bed at the place of unloading petroleum products located in the immediate vicinity of the cargo berth. The concrete of the track bed has been a subject to degradation as a result of many years of exploitation resulting, inter alia, in its cyclical flooding of petroleum products during the unloading and loading of rail tankers. Repairs carried out in the previous...
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Visible-light-driven lanthanide-organic-frameworks modified TiO2 photocatalysts utilizing up-conversion effect
PublicationHighly efficient and quite stable composite with core-shell-like architecture reported herein, responds to the challenge of sunlight-driven photocatalysts. The Ln(ndc)/TiO2 photocatalytic system comprises active lanthanide-carboxylate coordination networks (Nd, Er, Ho, and Tm as metal ions, and 2,6-naphthalene dicar-boxylic acid as the organic linker) and inert titanium dioxide and allow to convert incompatible visible radiation...
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Computer application for railway track realignment
PublicationThe topic of this article is the issue of railway track realignment. For this purpose, a computer software application was created that supports computations and generates a report needed for regulation of the trajectory of the railway. This program gives the ability to import data from measurement of the railway trajectory and then perform the calculation of the mathematical realignment. The result of this calculation is the basis...
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Design of Microstrip UWB Balun Using Quasi-TEM Approach Aided by the Artificial Neural Network
PublicationThe design procedure for UWB balun realized in the microstrip technology is proposed in the paper. The procedure applies Artificial Neural Network which corrects the dimensions of the approximate design found by appropriate scaling of the dimensions of the prototype. The scale coefficients for longitudinal and transverse dimensions of microstrip lines are determined from electromagnetic modeling based on transmission line equations....
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A two dimensional approach for modelling of pennate muscle behaviour
PublicationThe purpose of this study was to elaborate a two-dimensional approach for unipennate and bipennate striated skeletal muscle modelling. Behavior of chosen flat pennate muscle is modelled as a rheological system composed of serially linked passive and active fragments having different mechanical properties. Each fragment is composed of three elements: mass element, elastic element and viscous element. Each active fragment furthermore...
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The role of robotisation in improving bakery product quality
PublicationThe article aims to present the role of robotisation in increasing bakery product quality, as it is closely linked to machine reliability, as well as hygienic and sanitary conditions. All machines employed in the production process ought to be maintained at full production potential and reliability, which also has a fundamental influence on the final product’s quality. While participating in the 2014-2020 Smart Growth Operational...
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Synthesis, Molecular Structure, Anticancer Activity, and QSAR Study of N-(aryl/heteroaryl)-4-(1H-pyrrol-1-yl)Benzenesulfonamide Derivatives
PublicationA series of N-(aryl/heteroaryl)-4-(1H-pyrrol-1-yl)benzenesulfonamides were synthesized from 4-amino-N-(aryl/heteroaryl)benzenesulfonamides and 2,5-dimethoxytetrahydrofuran. All the synthesized compounds were evaluated for their anticancer activity on HeLa, HCT-116, and MCF-7 human tumor cell lines. Compound 28, bearing 8-quinolinyl moiety, exhibited the most potent anticancer activity against the HCT-116, MCF-7, and HeLa cell lines,...
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Synthesis, structure and properties of poly(ether-urethane)s synthesized using a tri-functional oxypropylated glycerol as a polyol
PublicationThe main aim of this work was to obtain poly(ether-urethane)s using tri-functional polyoxyalkylene polyol (Rokopol G1000), which introducing the chemical cross-links into the structure of polyurethanes. Poly(ether-urethane)s were prepared using two-step method, called prepolymer method, which involves in the first step the reaction of 4,4'-diphenylmethane diisocyanate (MDI) and tri-functional polypropylene glycol glycerol triether...
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How can HSR promote inter-city collaborative innovation across regional borders?
PublicationMany studies have shown that high-speed rail (HSR) can reshape the spatial pattern of economic geography. However, there needs to be more logical argumentation and rigorous empirical design on the paths and mechanisms involved. This paper considers the impact of the border effect on HSR links and innovation clusters from the perspective of inter-regional collaborative innovation. It provides a logical and compact theoretical...
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Selection of circuit geometry for miniaturized microwave components based on concurrent optimization of performance and layout area
PublicationThe paper presents a framework for automated EM-driven circuit geometry selection of miniaturized microwave components. Selection of a particular layout is based directly on miniaturization rates achieved for a set of candidate circuit geometries. Size reduction of the considered structures is obtained by replacing their main building blocks (i.e., conventional transmission lines) with slow-wave composite cells and meander lines....
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Synthesis and Biological Evaluation of Acridine/Acridone Analogs as Potential Anticancer Agents
PublicationAcridine and acridone analogues were prepared by Ullmann condensation and then cyclization reaction. As a result of nucleophilic substitution reaction 1-nitro-9-phenoxyacridine or 1-chloro-4-nitro-9(10H)-acridone with the corresponding peptides, the planned acridine derivatives (10a-c, 12, 17-a-d, 19) have been obtained. The cytotoxic activity of the newly obtained analogs were evaluated against melanotic (Ma) and amelanotic (Ab)...
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Structural factors affecting affinity of cytotoxic oxathiole-fused chalcones toward tubulin
PublicationSynthesis, in vitro cytotoxic activity, and interaction with tubulin of (E)-1-(6-alkoxybenzo[d][1,3]oxathiol- 5-yl)-3-phenylprop-2-en-1-one derivatives (2) are described. Some of the compounds demonstrated cytotoxic activity at submicromolar concentrations, and the activity could be related to interaction with tubulin at the colchicine binding site. Interaction of selected derivatives with tubulinwas evaluated using molecular modeling,...
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The influence of welding heat input on the quality and properties of high strength low-alloy dissimilar steel butt joints
PublicationThe paper presents the results of non-destructive and destructive tests of dissimilar highstrength low-alloy S460ML and S460N steel butt joints. These steels are characterized by similar mechanical properties, but their carbon equivalent CeIIW values are much different. The joints were made using different values of heat input for each welding bead. They were tested by non-destructive methods: visual, penetrant, radiographic and...
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Effect of electrode waterproof coating on quality of underwater wet welded joints
PublicationIn this paper, the effects of different hydrophobic coatings on the surface of covered electrodes on the quality of wet welded carbon steel joints were discussed. Commonly available hydrophobic substances used in industrial applications were selected for the research. The aim of using waterproof coatings was to check the possibility to decreasing the susceptibility of highstrength low-alloy S460N steel to cold cracking. During...
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Digitalization of High Speed Craft Design and Operation Challenges and Opportunities
PublicationIn recent years, global demands for safe and sustainable ships led to dramatic changes in the maritime industry. Digitalization is expected to play an important part in the future. This is supported by analysis of the autonomous ships market which shows that digitalization of large ship types such as tankers and container ships is well on track. Although to date designs of autonomous High-Speed Craft (HSC) have been developed,...
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NEW CONCEPT OF HYBRID PROPULSION WITH HYDROSTATIC GEAR FOR INLAND WATER TRANSPORT
PublicationThe article presents the development of author’s concept of a diesel/hydraulic propulsion system for inland watercraft. Due to specific nature of vessel navigation on rivers, classical propulsion systems with shaft lines can be effectively replaced by systems with hydraulic power transmission. A solution is also presented of a hybrid design with extra electric port having the form of a pumping system driven from a battery of accumulators....
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Magnetic field maps of an astable multivibrator in frequency range from 100 kHz to 50 MHz
Open Research DataThe data presents a result of near field measurements of electromagnetic emissions radiated from the PCB of a small electronic device. An efficient method of modelling the magnetic and electric field emissions is the measurements in the near field using electric and magnetic probes. The attached files contain magnetic field maps created on based measurements...
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Optical glyphs based localization and identification system
PublicationThe paper presents a description of functioning of a platform supporting the detection of obstructive diseases in the respiratory system education process. A 16-parameter model of the respiratory system simulated in the MATLAB/Simulink environment was set in the role of the tested patient. It has been linked to the control layer, developed in the LabVIEW environment, using the SIT library (Simulation Interface Toolkit). This layer...
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An application supporting the educational process of the respiratory system obstructive diseases detection
PublicationThe paper presents a description of functioning of a platform supporting the detection of obstructive diseases in the respiratory system education process. A 16-parameter model of the respiratory system simulated in the MATLAB/Simulink environment was set in the role of the tested patient. It has been linked to the control layer, developed in the LabVIEW environment, using the SIT library (Simulation Interface Toolkit). This layer...
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The role of water in deep eutectic solvent-base extraction
PublicationDeep eutectic solvents (DESs) are currently being used in different sectors, such as electrochemistry, electrodeposition, organic synthesis, nanoparticle preparation, bioactive compound separation, etc. Their use in analytical chemistry has only recently begun to expand. Despite the publication of a sufficient number of DES-based analytical extraction procedures, some details, such as interaction of DESwith the sample and target...
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Routing decisions independent of queuing delays in broadband leo networks
PublicationThis paper presents an analysis of queuing and propagation delays of Inter-Satellite Links (ISLs) in broadband Low-Earth Orbit (LEO) satellite networks. It is shown that queuing delays are negligible in all reasonable working conditions of the broadband ISL network. This fact makes it possible to simplify the routing protocols in such networks and permits using already known multi-commodity flow solutions for routing. The performance...
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Digital technologies and women's empowerment – casting the bridges
PublicationThis work briefly discusses the nexuses between digital technology development and adoption across societies, and its potential impact on overall welfare through women’s economic empowerment. In the first section it sets out the context and background. Next, Section 2 demonstrates the state of access to and the use of digital technologies across the world. Section 3 intends to trace the causal links and channels of digital technologies'...
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Linking music data in executable documents
PublicationThis paper presents the application of Interactive Open Document Architecture (IODA) to music and video data. This architecture was design to create multilayer documents which consist of many files. The paper shows the method of creating media documents on the basis of IODA. These kind of documents were called IODA Media Documents (IMD). IMD have links that connect many different kinds of files containing music and video data....
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The image of the City on social media: A comparative study using “Big Data” and “Small Data” methods in the Tri-City Region in Poland
Publication“The Image of the City” by Kevin Lynch is a landmark planning theory of lasting influence; its scientific rigor and relevance in the digital age were in dispute. The rise of social media and other digital technologies offers new opportunities to study the perception of urban environments. Questions remain as to whether social media analytics can provide a reliable measure of perceived city images? If yes, what implication does...
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Comparison of Renewable Energy Sources in ‘New’ EU Member States in the Context of National Energy Transformations
PublicationThe European Union strives to create sustainable, low-carbon economies; therefore, energy policies of all member states should move towards renewable energy sources (RES). That concerns also the so-called new EU member states. These countries, on the one hand, are characterized by significant historical similarities in terms of post-communist legacy and adopted development strategies linked with the EU membership, and on the other...
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New Peptide Based Fluconazole Conjugates with Expanded Molecular Targets
PublicationInfections of Candida spp. etiology are frequently treated with azole drugs. Among azoles, the most widely used in the clinical scenario remains fluconazole (FLC). Promising results in treatment of dangerous, systemic Candida infections demonstrate the advantages of combined therapies carried out with combinations of at least two different antifungal agents. Here, we report five conjugates composed of covalently linked FLC and...