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Search results for: REGENERATIVE BRAKING
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Estimation of the Regenerative Braking Process Efficiency in Electric Vehicles
PublicationIn electric and hybrid vehicles, it is possible to recover energy from the braking process and reuse it to drive the vehicle using the batteries installed on-board. In the conditions of city traffic, the energy dissipated in the braking process constitutes a very large share of the total resistance to vehicle motion. Efficient use of the energy from the braking process enables a significant reduction of fuel and electricity consumption...
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Analysis of the regenerative braking process for the urban traffic conditions
PublicationIn a regular drive system, with an internal combustion engine, vehicle braking is connected with the unproductive dissipation of kinetic and potential energy accumulated in the mass of the vehicle into the environment. This energy can constitute up to 70% of the energy used to drive a vehicle under urban conditions. Its recovery and reuse is one of the basic advantages of hybrid and electric vehicles. Modern traffic management...
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Designing of Parking Spaces on Parking Taking into Account the Parameters of Design Vehicles
PublicationNowadays, in all cities, there is an acute problem of a lack of parking spaces. The number of vehicles is constantly increasing not only in big cities and megacities, but also in small towns of the country, and there are not enough parking places—the pace of solving the problem is several times slower than the growth rate of transport among citizens. The paper is dedicated to the determination of an optimal size of a parking place...
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Regenerative Therapy
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Regenerative Biomaterials
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Regenerative Medicine
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Monitoring Regenerative Heat Exchanger in Steam Power Plant by Making Use of the Recurrent Neural Network
PublicationArtificial Intelligence algorithms are being increasingly used in industrial applications. Their important function is to support operation of diagnostic systems. This paper pesents a new approach to the monitoring of a regenerative heat exchanger in a steam power plant, which is based on a specific use of the Recurrent Neural Network (RNN). The proposed approach was tested using real data. This approach can be easily adapted to...
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From Regenerative Buildings to Regenerative Urban Projects: Design frameworks to scale up within the area of regenerative practice
PublicationIn this chapter, a discussion will be presented of design frameworks and assessment tools that are useful for boosting the scale jumping of regenerative design practices and the paradigm shift. Our main objectives will be to identify existing design and assessment frameworks, to describe the way they work and how they can contribute to scale-jumping regenerative design, as well as to identify shortcomings and opportunities. We...
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Regeneration
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Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration
PublicationDespite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...
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npj Regenerative Medicine
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Regenerative Medicine Research
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Current Regenerative Medicine
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DESIGNING OF PARKING SPACES TAKING INTO ACCOUNT THE PARAMETERS OF DESIGN VEHICLES IN RUSSIA
PublicationNowadays, in all the cities, there is an acute problem of a lack of parking spaces. The number of vehicles are becoming more and more larger, not only in megacities, but in small cities of the country, as well and there are no more parking places - the pace of solving the problem is several times slower than the rate of the transport growth among the citizens. The article is dedicated to the determination of the optimum sizes parking...
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Cardinal regenerative features of the MRL mouse
PublicationIn this review, we discuss recent studies relating to major features of adult MRL mouse biology that contribute to the regenerative responses seen. These include an increased inflammatory cell profile, a unique glycolytic metabolic state typically found during embryogenesis, and a cell cycle phenotype of DNA damage and G2/M arrest. These traits have been found in other mammalian and non-mammalian regenerative systems. How these...
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The Use of Big Data in Regenerative Planning
PublicationWith the increasing significance of Big Data sources and their reliability for studying current urban development processes, new possibilities have appeared for analyzing the urban planning of contemporary cities. At the same time, the new urban development paradigm related to regenerative sustainability requires a new approach and hence a better understanding of the processes changing cities today, which will allow more efficient...
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Big Data in Regenerative Urban Design
PublicationWhy the use of Big Data in regenerative planning matters? The aim of this chapter is to study under what conditions Big Data can be integrated into regenerative design and sustainable planning? Authors seek to answer how – when related to the ecosystem and to human activities – Big Data can be used to: • both shape policies that support the development of regenerative human settlements, • support restorative design for practitioners...
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Cell Regeneration
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Inflammation and Regeneration
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Engineered Regeneration
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Applications of the regenerative capacity of platelets in modern medicine
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Transient operation analysis of a regenerative heat exchanger.
PublicationReferat dotyczy problemu niestacjonarnej pracy wymiennika regenearcyjnego.Przedstawiono w nim uproszczony model matematyczny pozwalający oszacować w sposób ilościowy wielkość stałych czasowych wymiennika.
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CARDINAL REGENERATIVE FEATURES OF THE MRL MOUSE — AN UPDATE
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Tissue Engineering and Regenerative Medicine
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Regenerative Engineering and Translational Medicine
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Insight into heart regeneration
PublicationThe mammalian heart is thought to be incapable of regeneration because of the limited ability of cardiomyocytes. to proliferate. However, it has been recently shown that the neonatal murine heart is able to restore its normal function after coronary artery ligation or even partial resection. Unfortunately, this feature is lost in a few days after birth, although lower vertebrates as zebrafish or newt, retain this ability until adulthood. Therefore,...
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The role of epigenetics in regeneration
PublicationComplex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...
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Regenarative tourism – between theory and practice
PublicationPurpose: The aim of this article is to present a shift in thinking in terms of implementing the systems and practices needed to transition to a regenerative approach in tourism. The article aims to provide concrete ways to change thinking and move towards a regenerative paradigm in the tourism industry. Design/methodology/approach: This viewpoint paper defines regenerative tourism and explores its principles and the possibilities...
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How important are scaffolds and their surface properties in regenerative medicine
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Defining the smart-city in the context of regenerative design and planning
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Numerical Determination of the Load-Bearing Capacity of a Perforated Thin-Walled Beam in a Structural System with a Steel Grating
PublicationThis article presents the results of numerical simulations of a structural system consisting of steel perforated thin-walled beams and a steel grating. The simulations were conducted using the finite element method. The analysis took into account physical and geometric nonlinearity as well as the contact between the steel grating and the beams. The main goal of the research was to develop load-bearing curves for the main beam in...
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Brain perfusion imaging with the use of parametric modelling basing on DSC-MRI data
PublicationW pracy do estymacji parametrów perfuzji mózgu: przepływu krwi mózgowej (cerebral blood flow, CBF), objętości krwi mózgowej (cerebral blood volume, CBV) oraz średniego czasu przejścia (mean transit time, MTT) wykorzystano pomiary DSC-MRI (Dynamic Susceptibility Contrast Magnetic Resonance Imaging). W modelowaniu danych MRI zastoswoano model trzykompartmentowy. Przedstawiono i porównano dwa podejścia do identyfikacji modelu różniące...
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Polydopamine Biomaterials for Skin Regeneration
PublicationDesigning biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of...
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Identity and authenticity in urban regeneration
PublicationArtykuł dotyczy zagadnienia relacji pomiędzy kwestiami ochrony autentyzmu a budowy jego tożsamości w programach rewitalizacji urbanistycznej.
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CyberEye: New Eye-Tracking Interfaces for Assessment and Modulation of Cognitive Functions beyond the Brain
PublicationThe emergence of innovative neurotechnologies in global brain projects has accelerated research and clinical applications of BCIs beyond sensory and motor functions. Both invasive and noninvasive sensors are developed to interface with cognitive functions engaged in thinking, communication, or remembering. The detection of eye movements by a camera offers a particularly attractive external sensor for computer interfaces to monitor,...
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Neural Regeneration Research
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Application of 3D- printed hydrogels in wound healing and regenerative medicine
PublicationHydrogels are three-dimensional polymer networks with hydrophilic properties. The modifiable properties of hydrogels and the structure resembling living tissue allow their versatile application. Therefore, increasing attention is focused on the use of hydrogels as bioinks for three-dimensional (3D) printing in tissue engineering. Bioprinting involves the fabrication of complex structures from several types of materials, cells,...
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Degenerative Neurological and Neuromuscular Disease
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Journal of Stem Cells & Regenerative Medicine
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Urban Waterfront Regeneration: Origins of the Issue
PublicationThis paper deals with the origins of the issue of urban waterfront regeneration. The process of city-water interface was described with references to the three generations of port structures.
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Proximal fibular osteotomy as a treatment for degenerative meniscal extrusion
PublicationMeniscal extrusion treatment is a key focus area for research and clinical study of degenerative knee pathology. The contact forces between the meniscus and the bones cause external displacements of the meniscus that are resisted by the circumferential fibres. The main risk factors for the excessive deformation of the meniscus are meniscal root tears, disruption of the circumferential fibres, knee malalignment and high body mass...
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The differentiation and transdifferentiation of epithelial cells in vitro – is it a new strategy in regenerative biomedicine?
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Polyurethane porous scaffolds (PPS) for soft tissue regenerative medicine applications
PublicationTissue engineering requires suitable polymeric scaffolds, which act as a physical support for regenerated tissue. A promising candidate might be polyurethane (PUR) scaffold, due to the ease of the PUR properties design, which can be adjusted directly to the intended purpose. In this study, we report a successful fabrication of porous polyurethane scaffolds (PPS) using solvent casting/particulate leaching technique combined with...
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Activation of endogenous regenerative potential in mammals using epigenetic inhibitor zebularine
PublicationIn this work, a nucleoside inhibitor of DNA methyltransferases, zebularine, was investigated as a wound healing and regeneration promoting agent. It was found that a high dose of intraperitoneally delivered zebularine improved punch wound closure in the ear pinna in mice. Both cytidine, a zebularine analogue, and uridine, a zebularine metabolite, did not promote ear pinna hole closure. The effect of zebularine on ear pinna healing...
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On making operational decisions with taking into account value of operation applied to ship main propulsion engine as an example
PublicationObiektywizm i racjonalność w podejmowaniu decyzji eksploatacyjnych, są podstawowymi warunkami umożliwiającymi ich optymalny wybór. Zmusza to, do stosowania ocen ilościowych rozpatrywanych kryteriów, a tym samym do poszukiwania takich wskaźników, które w danej sytuacji pozwolą uznać jedną z wielu rozpatrywanych decyzji za najbardziej odpowiednią.Dokładne określenie zadania dla systemu energetycznego (np. zadania transportowego dla...
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Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries
PublicationOne of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative...
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Ecological bearing systems for water turbines - two research programs aimed at making water turbines more "eco-friendly".
PublicationW pracy opisano próby wyeliminowania ropopochodnych środków smarowych z układów łożyskowania turbin wodnych. Próby dotyczą zastosowania bezsmarowych łożysk kierownic i smarowanych wodą łożysk wałów turbin. Wprowadzanie bezsmarowych łożysk kierownic wymaga stworzenia metod prognozowania ich trwałości w warunkach małych oscylacji. Do stosowania w łożyskach wałów zaproponowano smarowane wodą łożyska ceramiczne o oryginalnej konstrukcji,...
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Human amniotic-fluid-derived stem cells: a unique source for regenerative medicine
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Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential
PublicationBackground The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life. DNA methylation is an epigenetic mechanism which plays a crucial role in development and gene expression regulation. Under investigation here are the changes in DNA methylation and gene expression patterns which accompany the loss of regenerative potential. Results The...
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Regenerative Drug Discovery Using Ear Pinna Punch Wound Model in Mice
PublicationThe ear pinna is a complex tissue consisting of the dermis, cartilage, muscles, vessels, and nerves. Ear pinna healing is a model of regeneration in mammals. In some mammals, including rabbits, punch wounds in the ear pinna close spontaneously; in common-use laboratory mice, they remain for life. Agents inducing ear pinna healing are potential regenerative drugs. We tested the effects of selected bioactive agents on 2 mm ear pinna...