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wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: klebsiella pneumoniae, ndm (new delhi metallo-β-lactamase), blandm, metalo-β-laktamazy.
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<i>N,N,N</i>-Trimethyl-N-(methyl 5-deoxy-2,3-<i>O</i>-isopropylidene-β-D-ribofuranosid-5- yl)ammonium 4-methylbenzenesulfonate sesquihydrate.
PublikacjaThe structure of the title compound, [C12H24NO4][C7H7O3S]·1.5H2O, contains alternating layers parallel to (001) of hydrophobic and polar character, stabilized by C-H...O hydrogen bonding. The furan ring adopts an envelope conformation with the C(OMe) atom as the flap, and the dioxolane ring is twisted about one of the O-C(methine) bonds. A comparison to related compounds is presented. The tosylate-O atoms were disordered over two...
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Harry R. Moody and Jennifer R. Sasser (2012). Aging: Concepts and Controversies (7th edition). Los Angeles, London, New Delhi, Singapore and Washington, DC: Sage Publications, 576 pp. ISBN 978 1 4522 0309 6 (paperback)
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Multiple Solutions to Third-Order Differential Equations with Derivative Dependence and Deviating Arguments
PublikacjaIn this paper, we give some new results for multiplicity of positive (nonnegative) solutions for third-order differential equations with derivative dependence, deviating arguments and Stieltjes integral boundary conditions. We discuss our problem with advanced argument α and arbitrary β ∈ C([0,1],[0,1]), see problem (2). It means that argument β can change the character on [0,1], so β can be delayed in some set J ⊂ [0,1] and advanced...
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Land of New Towns
PublikacjaReflexions on new towns throught the history.
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Market knowledge and new product performance: the mediating effects of new product performance
PublikacjaMarket knowledge is recognised as an important predictor of new product performance, which existing studies have proven. However, a missing link in this relationship is creativity, and specifically, as a natural process in product innovation. This study aims to examine a model that includes two mediating mechanisms between market knowledge scope and two new product outcomes, respectively: a new product’s competitive advantage and...
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Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with beta-glucosidase, beta-fucosidase and beta-galactosidase activities.
PublikacjaBackground: Cold-active enzymes, sourced from cold-adapted organisms, are characterized by high catalytic efficiencies at low temperatures compared with their mesophilic counterparts, which have poor activity. This property makes them advantageous for biotechnology applications as it: (i) saves energy costs, (ii) shortens the times for processes operated at low temperatures, (iii) protects thermosensitive substrates or products...
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Diversity of fecal coliforms and their antimicrobial resistance patterns in wastewater treatment model plant.
PublikacjaThe occurrence of resistance patterns among wastewater fecal coliforms was determined in the study. Susceptibility of the isolates was tested against 19 antimicrobial agents: aminoglycosides, aztreonam, carbapenems, cephalosporines, b-lactam/b-lactamase inhibitors, penicillines, tetracycline, trimethoprim/sulfamethoxazole, and fluoroquinolones. Additionally the removal of resistant isolates was evaluated in the laboratory-scale...
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Presence of Chlamydophila pneumoniae DNA in blood cells is a frequent event in patients with the late stage of primary cutaneous lymphomas and with atopic dermatitis
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Synteza nowych aminokwasowych i peptydowych analogów kwasu mykofenolowego oraz ich aktywność biologiczna i mikrobiologiczna
PublikacjaKwas mykofenolowy (MPA) oraz jego dwie stosowane klinicznie pochodne: mykofenolan sodu (MPS, CellCept) i mykofenolan mofetylu (MMF, Myfortic) są jednymi z najczęściej używanych leków hamujących proliferację limfocytów. Obok aktywności immunosupresyjnej, farmaceutyk wykazuje również właściwości przeciwbakteryjne, przeciwgrzybicze, przeciwwirusowe a także przeciwnowotworowe. W ramach realizacji swojej pracy doktorskiej zaprojektowałam...
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A new concept of contemporary marketing
PublikacjaPurpose: This conceptual paper aims to propose a new concept of marketing that responds well to the needs of a changing world, taking into account the continuous development of the service economy and the revolution in the development of the Internet and related tools. Methodology/Approach: The proposed concept is based on well-researched theories: service marketing, experience marketing, relationship marketing and digital marketing...
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New Product Creativity Dimensions and Performance
PublikacjaA new product’s meaningfulness and novelty are recognized as two distinct and important dimensions. Thus, researchers started to investigate their impact on new product performance. However, researchers’ reports on the impact of novelty on performance are still mixed, and several issues need to be solved. One of these problems is comparing how strongly each of these dimensions affects the new product performance. The other is to...
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Antimicrobial resistance of Pseudomonas spp. isolated from wastewater and wastewater-impacted marine coastal zone
PublikacjaIn this study, species distribution and antimicrobial susceptibility of cultivated Pseudomonas spp. were studied in influent (INF), effluent (EFF), and marine outfall (MOut) of wastewater treatment plant (WWTP). The susceptibility was tested against 8 antimicrobial classes, active against Pseudomonas spp.: aminoglycosides, carbapenems, broad-spectrum cephalosporins from the 3rd and 4th generation, extended-spectrum penicillins,...
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New Materiality-towards ‘Media Environments
PublikacjaArticle presents media solutions providing new materiality of architectural spaces. Media solutions in architecture evolve in new forms. Articlepresentsboth the developmentof new technological solutionsas well as new ways of application of media solutions in relation toarchitectural form. The aim of the article is to show technical aspects of new materiality - intelligent materials, allowing transmission of changeable visual content...
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The need for new transport protocols on the INTERNET
PublikacjaThe TCP/IP protocol suite is widely used in IP networks, regardless of diverse environments and usage scenarios. Due to the fact of being the basic concept of organizing the work of the Internet, it is the subject of interest and constant analysis of operators, users, network researchers, and designers. The Internet is a "living" organism in which new needs appear all the time. This is particularly important due to the emerging...
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A new library for construction of automata
PublikacjaWe present a new library of functions that construct minimal, acyclic, deterministic, finite-state automata in the same format as the author's fsa package, and also accepted by the author's fadd library of functions that use finite-state automata as dictionaries in natural language processing.
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Unlocking creativity with new technologies
PublikacjaArtificial intelligence, augmented and virtual reality, Internet of Things and digital twins are just a few concepts related to the fourth industrial revolution that is happening right before our eyes. The key question asked by managers in the aerosol sector recently is: what does all this new technology mean to me?
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Overview of new product development strategies and models
PublikacjaMotivation: The motivation for the overview presented in this article is to provide a starting point for considering whether existing new product development methodology and its level of detail allows product teams to develop high-quality and business-effective product concepts. Aim: The aim of this article is recognise the current state of research into new product development methodology and to present the strategies and models...
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New results on estimation bandwidth adaptation
PublikacjaThe problem of identification of a nonstationary autoregressive signal using non-causal estimation schemes is considered. Noncausal estimators can be used in applications that are not time-critical, i.e., do not require real-time processing. A new adaptive estimation bandwidth selection rule based on evaluation of pseudoprediction errors is proposed, allowing one to adjust tracking characteristics of noncausal estimators to unknown...
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A new methof for identyfication of RTS noise
PublikacjaIn the paper a new method, called the Noise Scattering Pattern (NSP) method, for RTS noise identyfication in a noise signal is presented. Examples of patterns of the NSP method are included.
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Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems
PublikacjaSince human-associated bacteria have been recognized as vectors in two - way gene transmission between the pathogenic and environmental populations, health hazard connected with wastewater discharge requires reevaluation. In this paper the particular attention was given to antimicrobial-resistance of Escherichia coli and enterococci isolated from wastewater and wastewater impacted environments. The obtained results showed that...
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IN SEARCH OF A NEW EXHIBITION SPACE
PublikacjaThe buildings considered as raising the prestige and promoting cities are those related to culture. Their impact on urban life is undeniable, which is reflected in a continuous increase in the number of new museum buildings. Apart from places intrinsically linked with culture, which, as such, may be considered as standard - like museum, theatres or galleries - there also appear alternative places of development and promotion of...
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Creating new voices using normalizing flows
PublikacjaCreating realistic and natural-sounding synthetic speech remains a big challenge for voice identities unseen during training. As there is growing interest in synthesizing voices of new speakers, here we investigate the ability of normalizing flows in text-to-speech (TTS) and voice conversion (VC) modes to extrapolate from speakers observed during training to create unseen speaker identities. Firstly, we create an approach for TTS...
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B-GALACTOSIDASE ARTHROBACTER SP. 32cB - OBTAINING THE GENE SEQUENCE, CONSTRUCTION OF THE EXPRESSION SYSTEM, BIOSYNTHESIS AND BIOCHEMICAL CHARACTERIZATION OF THE ENZYME
PublikacjaINTRODUCTION: β-Galactosidase is an enzyme which catalyzes the hydrolysis of O glycosidic bond in β-galactosides. Another activity of β galactosidase is a transglycosylation activity. The main industrial use of this protein is the hydrolysis of lactose in milk in a cooling conditions. Synthesis of galactooligosaccharides, which are mostly used as a prebiotics added to some foods or available as dietary supplements, is only one...
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The new concept of product. Cooling band
PublikacjaThe chapter below presents the innovative solution consist in applying the cooling band to help holding the hot object. The solution was found through substitute inputs analysis and brain storm method. The new product was submitted in Polish Patent Office under the No. W.120905.
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New pathways for functionalization of phosphorus ligands
PublikacjaThe presented dissertation consistsof two main partsand focuses on the synthesis and characterization of new low-valent phosphorus compounds. Thesestudies have already been fully described in three JCR-journals. The first partdescribes the utilization ofselectedphosphanylphosphinidene transition metal complexes as a source of diversified phosphorus ligands. For thispurposethree complexes...
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Predicting Value of Binding Constants of Organic Ligands to Beta-Cyclodextrin: Application of MARSplines and Descriptors Encoded in SMILES String
PublikacjaThe quantitative structure–activity relationship (QSPR) model was formulated to quantify values of the binding constant (lnK) of a series of ligands to beta–cyclodextrin (β-CD). For this purpose, the multivariate adaptive regression splines (MARSplines) methodology was adopted with molecular descriptors derived from the simplified molecular input line entry specification (SMILES) strings. This approach allows discovery of regression...
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New Indoor Positioning Algorithm for Distance Measurements
PublikacjaIn the paper a new indoor positioning algorithm is presented. This algorithm takes into account selected features of radio wave propagation in indoor environment. This results in improvement in accuracy of calculated position estimates. A comparative analysis of this new algorithm with Chan and Foy algorithms was made and described in the paper. This comparative analysis was made with utilization of real radio distance measurements.
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New applications of sound and vision engineering
PublikacjaMultimedia, Sound & Vision Engineering are relatively new fields within the area of science and technology, but teaching and research in this area has been carried out at Gdansk University of Technology (Gdansk, Poland) for nearly 5 decades. Current project carried-out in the Multimedia Systems Department are in the scope of the paper.
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New Performance Indices for Power System Stabilizers
PublikacjaThe subject of the article is issues related to innovative indices for power system stabilizers (PSSs). These new indices will be able to quickly show which PSS (among many other PSSs) is not working properly and that advanced optimization and simulation methods should be used to improve the PSS settings. The authors note the fact that the acceptance requirements for PSSs are different in various power systems. Moreover, the authors...
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New conjugates of mycophenolic acid and their antiproliferative activity
PublikacjaThe new conjugates of mycophenolic acid (MPA) were obtained in the reaction of N6-(ω-aminoalkyl)adenosines with MPA in the presence of EDCI as a coupling reagent. New compounds 4a–h were evaluated on leukemia cell line (Jurkat) and PBMC from healthy donors. Length of the linker influenced observed activity. The compound 4b possessing 1,3-diamine spacer exhibited the most promising results and can be considered to further investigations.
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New generation of the satellite hydraulic pumps
PublikacjaHydraulic satellite machines are known and produced in many versions, recognizable by the number of humps on their inner rotor and external gear, and therefore by the number of cooperating gears (satellites). All known shapes were however designed on the base of preliminary assumption that rotor’s and external gear’s pitch lines are formed by merging arcs, tangent to each other in the. This assumption makes calculations easier,...
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Analysis-by-synthesis paradigm evolved into a new concept
PublikacjaThis work aims at showing how the well-known analysis-by-synthesis paradigm has recently been evolved into a new concept. However, in contrast to the original idea stating that the created sound should not fail to pass the foolproof synthesis test, the recent development is a consequence of the need to create new data. Deep learning models are greedy algorithms requiring a vast amount of data that, in addition, should be correctly...
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NEW TRENDS IN DEVELOPMENT OF ORC'S FOR MICROPOWER GENERATION
PublikacjaIn the paper, new trends in development of micropower generation of heat and electricity are presented. New type of CHP for domestic usage is developed in the Institute of Fluid-Flow Machinery PAS and methods of its design are presented. The most promising trends in equipment of ORC cycle for this purpose were discussed. Main attention was focused on micro-heat exchangers design based on micro-channels and micro-jets. In our opinion...
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Shaping the new face of the Imperial Shipyard in Gdańsk
PublikacjaThe main purpose of the article is to present the transformation process of the urban complex known as the Imperial Shipyard in Gdańsk. Its rich history and interesting location on the waterfront of the city as well as its proximity to the very centre makes this area a much sought-after location for the new urban development project, which is part of the wider new district in the city centre of Gdańsk – the Young City. The article...
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New trends in development of micro heat exchangers for ORC's
PublikacjaIn the paper, new trends in development of micro heat exchangers for CHP are presented. Main attention is concentrated on the question, how channels size and thermal development lenght affect the heat transfer. New types of micro heat exchangers developed at the Institute of Fluid-Flow Machinery PAS and the methoda of their design are presented. The new experimental testing methods of the micro-channel heat exchangers, new algorithms...
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The Urbanity Phenomenon – Tradition and New Cultural Iterations
PublikacjaCities that have managed to survive and rebuild lost urbanity do not close themselves towards new forms that are largely generated by culture. People are increasingly organized around common, local goals. They want to live in cities that open themselves up to differences, with culture as a tool for the revitalization of urbanity. Flexible management methods, tailored to the context and new needs, are therefore emphasized. Nowadays,...
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Unfolding new values in the landscape of conflict
PublikacjaThe main objective of the paper is to investigate how the conflict quality of landscape can be used as its asset and potential for creating new values. Like mediation between different overlapping archaeologies offers a basis for the perception of place in the chronology of time, the mediation between conflicted areas creates a capacious zone for enhancing the unique quality of landscape in its architectural, social, cultural and...
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A new approach to the stereoselective synthesis of trans-3-carbamoyl-b-lactam moieties†
PublikacjaOne-pot synthesis of optically active 1,4-disubstituted-3-carbamoyl-azetidinones from 5-[(N-arylamino)- (hydroxyl)methylene]-2,2-dimethyl-1,3-dioxa-4,6-diones and chiral aldimines is achieved via thermal generation of carbamoyl ketenes and subsequent [2+2] cycloaddition. Three possible chiral induction approaches were tested and (R)-(+)-1-phenylethylamine was confirmed as the best chiral auxiliary. Among the four possible diastereoisomers,...
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Comparison of new position estimation algorithm for indoor environment
PublikacjaIn the paper a new position estimation algorithm based on distance measurements is presented. This algorithm is dedicated for indoor environments. In the paper the new algorithm is compared with Chan algorithm. For the comparison were used real measurements conducted inside a building.
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A NEW MASTER'S DEGREE PROGRAM IN GEODESY
PublikacjaFaculty of Civil and Environmental Engineering (WILiS) at Gdansk University of Technology (GUT) offers studies in the fields of Geodesy and Cartography. The bachelor program (7 semesters) was started ten years ago in 2009. It provides the student with the basic skills and knowledge in the fields of surveying, geodesy and more generally geomatics and cartography. It is strongly related to expertise knowledge of civil building (geodetic...
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A new and convenient method for the preparation of functionalized phosphorothioates
PublikacjaA new and efficient method for the synthesis of alkyl and aryl phosphorothioates in high yields via the reaction of (5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorin-2-yl)disulfanyl derivatives with trimethyl phosphite was developed.
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A new look at the statistical identification of nonstationary systems
PublikacjaThe paper presents a new, two-stage approach to identification of linear time-varying stochastic systems, based on the concepts of preestimation and postfiltering. The proposed preestimated parameter trajectories are unbiased but have large variability. Hence, to obtain reliable estimates of system parameters, the preestimated trajectories must be further filtered (postfiltered). It is shown how one can design and optimize such...
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New polish catalogue of typical flexible and semi-rigid pavements
PublikacjaThe paper covers the following topics important for the development of the new Polish Catalogue of typical flexible and semi-rigid pavements: reasons for preparing the new issue of the Catalogue of typical flexible and semi-rigid pavements, items introduced in the new issue, organise the terminology related to pavements, design traffic calculations and new equivalent axle load factors,...
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New Algorithms for Adaptive Notch Smoothing
PublikacjaThe problem of extraction/elimination of a nonstationary complex sinusoidal signal buried in noise is considered. This problem is usually solved using adaptive notch filtering (ANF)algorithms. It is shown that accuracy of signal estimation can be increased if the results obtained from ANF are further processed using a cascade of appropriately designed filters. The resulting adaptive notch smoothing (ANS) algorithms can be employed...
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Production of new non-matrix reference material of ethene
PublikacjaThe main objective of the research is to produce new non-matrix reference materials of ethene. The study are based on thermal decomposition of surface compound chemically bonded with the surface of glass fibers coated with thin layer of aluminum. Positivehomogeneity test, stability test and organization of inter-laboratory comparison are leading to find new non-matrix reference materials which are indispensable tools in the analysis...
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A new division of bacterial UvrA homologues
PublikacjaThe UvrA protein is a DNA-binding and damage-recognition enzyme which participates in the prokaryotic type nucleotide excision repair (NER) pathway. It has recently been noted that some bacterial genomes comprise additional uvrA genes which encode five distinct types of UvrA homologue. We investigated the sequences of over 2400 bacterial genomes and found 130 examples of bacteria containing uvrA 2 genes. The sequence analyses conducted...
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Concept for Perfecting the Marketing of New Technologies at Gdańsk University of Technology
PublikacjaThe chapter discusses the problem of improving the use of modern marketing achievements in the development and offering of new technologies, based on the experience of the Gdansk University of Technology (PG). Were discussed the concept, features, benefits and conditions of modern marketing, as well as the essence of the new technologies and ways of transferring them from scientific research units to the economy. Presented past...
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New developments in preparation and use of standard gas mixtures
PublikacjaStandard gas mixtures are commonly applied in all stages of analytical work related to the analysis of gaseous samples. Numerous techniques for generating standard gas mixtures are in use. In this article, we present new developments regarding the production of standard gas mixtures, with particular focus on improvements in the application of dynamic techniques for generating them. Furthermore, we describe the application of new...
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The Impact of a New Product’s Novelty and Meaningfulness on its Commercial Performance
Publikacjas new product development (NPD) process encompasses creative actions, so a new product is characterized by two essential dimensions used to describe any creative output – namely novelty and meaningfulness. Therefore, businesses are faced with the questions to what extent and under what market conditions to develop each of these dimensions in order to obtain high new product commercial performance. Based on gaps indentified in the...
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New method for personalization of avatar animation
PublikacjaThe paper presents a method for creating a personalized animation of avatar utilizing fuzzy inference. First the user designs a prototype version of animation, with keyframes only for important poses, roughly describing the action. Then animation is enriched with new motion phases calculated by the fuzzy inference system using descriptors given by the user. Various degrees of motion fluency and naturalness are possible to achieve....