Filtry
wszystkich: 10308
-
Katalog
- Publikacje 9008 wyników po odfiltrowaniu
- Czasopisma 327 wyników po odfiltrowaniu
- Konferencje 19 wyników po odfiltrowaniu
- Osoby 232 wyników po odfiltrowaniu
- Wynalazki 1 wyników po odfiltrowaniu
- Projekty 32 wyników po odfiltrowaniu
- Aparatura Badawcza 8 wyników po odfiltrowaniu
- Kursy Online 172 wyników po odfiltrowaniu
- Wydarzenia 12 wyników po odfiltrowaniu
- Dane Badawcze 497 wyników po odfiltrowaniu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: kinetic model development
-
Model Assisted Statistics and Applications
Czasopisma -
Heat transfer characteristics of hybrid microjet – Microchannel cooling module
PublikacjaThe paper presents experimental investigation of heat transfer intensification in a microjet–microchannel cooling module. Applied technology takes benefits from two very attractive heat removal techniques. When jets are impinging on the surface, they have a very high kinetic energy at the stagnation point, also in microchannels boundary layer is very thin allowing to obtain very high heat fluxes. Main objective of this paper was...
-
Dissociative Electron Attachment to 5-Iodo-4-thio-2′-deoxyuridine: A Potential Radiosensitizer of Hypoxic Cells
PublikacjaIn the search for effective radiosensitizers for tumor cells, halogenated uracils have attracted more attention due to their large cross section for dissociation upon the attachment of low-energy electrons. In this study, we investigated dissociative electron attachment (DEA) to 5-iodo-4-thio-2'-deoxyuridine, a potential radiosensitizer using a crossed electron-molecule beam experiment coupled with quadrupole mass spectrometry....
-
How proteins bind to DNA: target discrimination and dynamic sequence search by the telomeric protein TRF1
PublikacjaTarget search as performed by DNA-binding proteins is a complex process, in which multiple factors contribute to both thermodynamic discrimination of the target sequence from overwhelmingly abundant off-target sites and kinetic acceleration of dynamic sequence interrogation. TRF1, the protein that binds to telomeric tandem repeats, faces an intriguing variant of the search problem where target sites are clustered within short fragments...
-
Electron-Induced Decomposition of 5-Bromo-4-thiouracil and 5-Bromo-4-thio-2′-deoxyuridine: The Effect of the Deoxyribose Moiety on Dissociative Electron Attachment
PublikacjaWhen modified uridine derivatives are incorporated into DNA, radical species may form that cause DNA damage. This category of molecules has been proposed as radiosensitizers and is currently being researched. Here, we study electron attachment to 5-bromo-4-thiouracil (BrSU), a uracil derivative, and 5-bromo-4-thio-20 -deoxyuridine (BrSdU), with an attached deoxyribose moiety via the N-glycosidic (N1-C) bond. Quadrupole mass spectrometry...
-
Przedsiębiorczość społeczna jako klucz do skutecznej edukacji przedsiębiorczej na społecznie odpowiedzialnym uniwersytecie
PublikacjaCel naukowy: Celem artykułu jest prezentacja nowej propozycji kształcenia na rzecz przedsiębiorczości na studiach biznesowych (zarządzanie i ekonomia), uwzględniającej edukację w zakresie przedsiębiorczości społecznej. Problem i metody badawcze: W artykule omówiono problem edukacji przedsiębiorczej z punktu widzenia wyzwań zmieniającej się gospodarki oraz ewoluujących oczekiwań stawianych polskim uczelniom wyższym. Główną metodą...
-
Analysis of muscles behaviour. Part II. The computational model of muscles group acting on the elbow joint
PublikacjaThe purpose of this paper is to present the computational model of muscles' group describing the movements of flexion/extension at the elbow joint in the sagittal plane of the body when the forearm is being kept in the fixed state of supination/pronation. The method ofevaluating the muscle forces is discussed in detail. This method is the basis for the quantitative and qualitative verification of the proposed computational model...
-
Diagnostic model of compression-ignition engine slide bearings for controlling the changes of their state
PublikacjaW artykule przedstawiono koncepcję umożliwiającą sterowanie procesami zmian stanów eksploatacyjnych silnika na podstawie modelu diagnostycznego łożysk ślizgowych. Jako model łożyska ślizgowego przyjęty został topologiczny model diagnostyczny, pozwalający na pełne i dokładne wykorzystanie oleju smarowego jako jednego z nośników informacji o stanie technicznym łożyska. Przedstawiona została przykładowa interpretacja stanów eksploatacyjnych...
-
Koncepcja i modelowanie silnika o wirującym tworniku oraz magneśnicy do zastosowania w napędzie miejskiego samochodu elektrycznego
PublikacjaW artykule zaprezentowano koncepcję, model oraz prototyp silnika z wirującym twornikiem oraz magneśnicą. Opisano historię powstania i zastosowania tego typu silników w motoryzacji. Przedstawiono nowoczesne rozwiązania konstrukcyjne i zastosowania we współczesnych samochodach elektrycznych i hybrydowych. Opracowano model silnika z wirującym twornikiem i magneśnicą oraz przedstawiono wybrane wyniki symulacji przeprowadzone w programie...
-
Wzory kreatywności. Koncepcja modelu prawdopodobieństwa działania kreatywnego jako narzędzie badania procesu twórczego w środowisku miejskim
PublikacjaWspółczesne koncepcje kształtowania miast, takie jak zrównoważony rozwój, miasto odporne, inteligentne miasto, miasto kreatywne, tworzą obecnie ramy urbanistyki o charakterze jednej uogólnionej idei kształtującej środowisko społeczno-materialne. Kontekstualne ujęcie badań kreatywności opisuje zależności między środowiskiem miejskim a twórczością w mieście kreatywnym. Ujęcie procesualne kreatywności stanowi hic et nunc urbanizmu,...
-
Models in spatial development
Kursy Online -
Potentials of Water Usage in urban Neighbourhood Structures
PublikacjaThis paper will treat about water influence and possibility of its usage in the urban neighborhood structures (e.g. districts, real estate properties, town parts) in the context of actual regional environmental problems and according to directories determined by European targets. It is not rare yet in the basic stage of urban design that water is treated as a threat, not a chance. In result planned structures are often built,...
-
Heat transfer characteristics of hybrid microjet -microchannel cooling module
PublikacjaThe paper presents the experimental investigation of heat transfer intensification in a microjet- microchannel cooling module. Applied technology takes benefits from two very attractive heat removal techniques. When jets are impinging on the surface, they have a very high kinetic energy at the stagnation point, also in microchannels boundary layer is very thin allowing to obtain very high heat fluxes. Main objective of this paper...
-
Heterogeneity of quaternary structure of glucosamine-6-phosphate deaminase from Giardia lamblia
PublikacjaThe oligoHis-tagged versions of glucosamine-6- phosphate deaminase from Giardia lamblia (GlmNagB-HisN, GlmNagB-HisC) were constructed and purified to hear homogeneity, and their kinetic and structural properties were compared to those of the wild-type enzyme (GlmNagB). Introduction of the oligoHis tag at the GlmNagB C-terminus resulted in almost complete loss of the catalytic activity, while the catalytic properties of GlmNagB-HisN...
-
Stone cutting industry waste-supported zinc oxide nanostructures for ultrasonic assisted decomposition of an anti-inflammatory non-steroidal pharmaceutical compound
PublikacjaPowdered stone waste (PSW) obtained from a stone cutting industrial unit was applied as support for the immobilization of nano-sized ZnO to be utilized as an effective catalyst for the catalytic conversion of acetaminophen (ACE) under ultrasonication. The incorporation of ZnO nanostructures into PSW structure enhanced the specific surface area and pore volume of the as-prepared nanocompound. The change in the value of zero point...
-
Experimental validation of pressure drop models during flow boiling of R134a – effect of flow acceleration and entrainment
PublikacjaA crucial step to assure proficient work of power and process apparatus is their proper design. A wide array of those devices operates within boiling or condensation of the working fluid to benefit from high heat transfer rates. Two-phase flows are associated with high heat transfer coefficients because of the latent heat of evaporation and high turbulence level between the liquid and the solid surface. Predicting heat transfer...
-
Why Are Left-Handed G-Quadruplexes Scarce?
PublikacjaG-quadruplexes (G4s) are nucleic acid structures crucial for the regulation of gene expression and genome maintenance. While they hold promise as nanodevice components, achieving desired G4 folds requires understanding the interplay between stability and structural properties, like helicity. Although right-handed G4 structures dominate the experimental data, the molecular basis for this preference over left-handed helicity is unclear....
-
Thermal visualization of Ostwald-de Waele liquid in wavy trapezoidal cavity: Effect of undulation and amplitude
PublikacjaThe present study is concerned with the numerical simulations of Ostwald-de Waele fluid flow in a wavy trapezoidal cavity in the presence of a heated cylinder situated at the center of the cavity. The work consists in characterizing the mixed convection as a function of the intensity of heat flow. The flow behaviour and temperature distribution in a cavity are the main focus of this study. The lower wall of the cavity is fixed...
-
Ryszard S. Romaniuk profesor
OsobyProfessor of Electronics, Computer and Communications Engineering at Warsaw University of Technology, Poland; Eisenhower Fellow, Philadelphia, MA USA; SPIE Fellow, Bellingham, WA USA; Editor-in-Chief, International Journal of Electronics and Telecommunications, Polish Academy of Sciences; Photonics Spectra Magazine, EAB Member; ORCID; GoogleScholar; ResearchGate; Publons; Scopus; PW; OWPW; PBN; NaukaPolska; IN;
-
Sustainable development on the background of a general theory of regional development
PublikacjaThe article focuses on a presentation and discussion of the concept of "sustainable de-velopment" (SD). It contains an analysis of the concept, its characteristics, objectives and principles of implementation. Particular emphasis has been placed on presentation of the unique features of sustainable development that distinguish it from other theories of regional development. Therefore, the discussion has been preceded by a discussion...
-
INVESTIGATION OF THE CHARACTERISTICS OF A LOWEMISSION GAS TURBINE COMBUSTION CHAMBER OPERATING ON A MIXTURE OF NATURAL GAS AND HYDROGEN
PublikacjaT his article is devoted to the investigation of the characteristics of a low-emission gas turbine combustion chamber, which can be used in Floating Production, Storage and Offloading (FPSO) vessels and operates on a mixture of natural gas and hydrogen. A new approach is proposed for modelling the processes of burning out a mixture of natural gas with hydrogen under preliminary mixing conditions in gaseous fuel with an oxidizer...
-
Manufacturing and Recycling Impact on Environmental Life Cycle Assessment of Innovative Wind Power Plant Part 2/2
PublikacjaThe process of conversion of wind kinetic energy into electricity in innovative wind power plant emits practically no harmful substances into the environment. However, the production stage of its components requires a lot of energy and materials. The biggest problem during production plan-ning process of an innovative wind power plant is selection of materials and technologies and, consequently, the waste generated at this stage....
-
Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA
PublikacjaG-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 motifs form in vivo and are implicated in regulation of such processes as gene expression and chromosome maintenance. The structure and stability of various G4 topologies were determined experimentally; however, the driving forces for their formation are not fully...
-
Polityka Rozwoju/Development Policy
Kursy OnlineZajęcia dotyczą wyzwań realizacji 11 celu Światowej Polityki Zrównoważonego Rozwoju czyli kwestii budowania odpornych społeczności miejskich w krajach rozwijających się Wykłady odbywają się w formule zdalnej w układzie zajęć zblokowanych wg indywidualnego planu. prowadząca: dr Gabriela Rembarz grem@pg.edu.pl
-
Wodociągi - model. komput., stacjon., I sem mgr 2023/2024
Kursy OnlineKurs dotyczy przedmiotu Modelowanie systemów wodociągowych na Kierunku Inżynieria Środowiska, studia stacjonarne II stopnia, sem.I. W ramach przedmiotu (wykłady, ćwiczenia, projektowanie) dostarczana jest studentom uporządkowana, możliwie kompletna wiedza umożliwiająca wykonywanie prac projektowych i analitycznych dla systemów transportu i dystrybucji wody wodociągowej (STiDW) z wykorzystaniem modelowania komputerowego przepływów ...
-
New propagation model for wireless monitoring systems in the container terminal environment
PublikacjaW artykule został poddany analizie problem szacowania tłumienia propagacyjnego na obszarze terminala kontenerowego. Została opisana kampania pomiarowa, której rezultatem było opracowanie nowego modelu propagacyjnego dla łącza radiowego pracującego w warunkach LOS i NLOS.
-
Comparison of heat transfer characteristics in surface cooling using microjets with water, ethanol and HFE7100 as test fluids
PublikacjaAccurate control of cooling parameters is required in ever wider range of technical applications. It is known that reducing the dimensions of the size of nozzle leads to an increase in the economy of cooling and improves its quality. Present study describes research related to the design and construction of the nozzles and microjet study, which may be applied in many technical applications such as in metallurgy, electronics, etc....
-
Overview of new product development strategies and models
PublikacjaMotivation: The motivation for the overview presented in this article is to provide a starting point for considering whether existing new product development methodology and its level of detail allows product teams to develop high-quality and business-effective product concepts. Aim: The aim of this article is recognise the current state of research into new product development methodology and to present the strategies and models...
-
Overview of new product development strategies and models
PublikacjaMotivation: The motivation for the overview presented in this article is to provide a starting point for considering whether existing new product development methodology and its level of detail allows product teams to develop high-quality and business-effective product concepts. Aim: The aim of this article is recognise the current state of research into new product development methodology and to present the strategies...
-
Development of spatial structures, PG_00053620
Kursy Online -
Civilization Threats and Sustainable Development
Kursy Online -
Development of spatial structures_2023/24
Kursy Online -
Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublikacjaThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
-
Chemical and biological evaluation of antioxidant activity of endogenous redox-active compounds compared to plant-derived exogenous antioxidants
PublikacjaThe research conducted so far has shown that endogenous antioxidants, despite being regarded as the first line of antioxidant defense, may not be sufficient to maintain redox homeostasis in cells exposed to oxidative stress. The results obtained in the doctoral dissertation show that endogenous redox-active compounds were moderate or weak scavengers of ABTS and DPPH radicals, while in cellular setting, their impact on the reducing...
-
The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives
PublikacjaThe term ‘vitamin C’ describes a group of compounds with antiscorbutic activity of L-ascorbic acid (AA). Despite AA’s omnipresence in plant-derived foods, its derivatives have also been successfully implemented in the food industry as antioxidants, including the D-isomers, which lack vitamin C activity. This study aimed to determine the relationship between redox-related activities for five derivatives of AA using electrochemical,...
-
Ab initio chemical kinetics of Isopropyl acetate oxidation with OH radicals
PublikacjaGlobal reactivity descriptors of isopropyl acetate (IPA) and thermo-kinetic aspects of its oxidation via OH radicals have been studied. Transition state theory (TST) was utilized to estimate the bimolecular rate constants. Ten oxidation pathways have been investigated, and all of them are exothermic. The potential energy diagram has been sketched using different pre- and post-reactive complexes for all reaction pathways. Rate coefficient...
-
Increasing the rate of sustainable change: a call for a redefinition of the concept and the model for its implementation
PublikacjaW pracy dokonano analizy problemu dużej rozbieżności pomiędzy zaproponowanymi strategiami a efektywnością akcji podjętych w celu wprowadzenia w praktyce zasad zrównoważonego rozwoju. Podkreślono konieczność współpracy różnych organizacji i samorządów lokalnych oraz uwzględniono rolę szkół wyższych w procesie wprowadzania zasad zrównoważonego rozwoju.
-
Webinarium „Drug Discovery, Development & Commercialization”
WydarzeniaCTWT PG zaprasza na webinarium „Drug Discovery, Development & Commercialization”. Spotkanie skierowane jest do osób zajmujących się zawodowo lub planujących swoją karierę w dziedzinie opracowywania i rozwoju leków.
-
An Approach to Trust Case Development
PublikacjaIn the paper we present an approach to the architectural trust case development for DRIVE, the IT infrastructure supporting the processes of drugs distribution and application. The objectives of DRIVE included safer and cheaper drugs distribution and application. A trust case represents an argument supporting the trustworthiness of the system. It is decomposed into claims that postulate some trust related properties. Claims differ...
-
Modern Methods of Software Development
PublikacjaSoftware development methods consist of such activities like analysis, planning, development, testing, deployment, maintenance and retirement. All of them can be divided into two main categories - traditional and agile. The objective of this paper is to review some of the most popular traditional, agile and open source development methods. Special attention was paid to the common stages of all methods - testing and maintenance.
-
state aid for sustainable urban development
Dane BadawczeThe dataset encompassed a choice of important legal acts with respect on the usage of EFRD for urban projects, a list of selected bibliography as well as a list of selected individual notifications of state aid measures being part of the Sustainable Urban Development Programme in the period 2014- 2020. As a comparison, an example of individual EC decision...
-
Applying agiile practices to the development of safety-critical software
PublikacjaDevelopment of safety critical software is subjected to numerous restrictions and recommendations. To meet these requirements classical software development models (e.g. V-model) are usually applied. Agile methodologies, although rapidly increasing their popularity, were generally regarded as unsuitable for such projects. However, they offer potential benefits which provide a strong incentive to incorporate them into safety-critical...
-
Evaluation the environmental fate of pharmaceuticals using a level III model based on poly-parameter linear free energy relationships
PublikacjaOpisano możliwości zastosowania modelu ''Level III Model'' do opisu losu środowiskowego pozostałości farmaceutyków w środowisku. Zastosowany model umożliwia oszacowanie trwałości, stężeń oraz transportu poszczególnych zanieczyszczeń pomiędzy poszczególnymi elementami składowymi środowiska (powietrze, woda, gleba i osady denne).
-
Model of a Maturity Capsule in Managing IT Projects
PublikacjaThe main purpose of this article is to present a report on the development of a model of information technology management (MITM). This model is an answer to the need to support decision making in the selection of methods and information technologies. This article presents a multisequential model (MSM) of technology selection and a model for initial processing procedures (IPP) necessary for the MITM model. The presentation of the...
-
Preliminary Testing of the Influence of Modified Polycaprolactones on Anabaena Variabilis Growth in Seawater
PublikacjaSeveral new biodegradable polymer materials have recently come onto the global market. Mostly the results on degradation kinetic studies are presented. This paper suggests using one of the tests to estimate the impact of polymer packaging material on sea life. The microorganism chosen was Anabaena variabilis (identified in many waters, including those of the Baltic Sea, especially in the Gulf of Gdansk and Puck Bay; this cyanobacterium...
-
A comparative study on the decolorization of Tartrazine, Ponceau 4R, and Coomassie Brilliant Blue using persulfate and hydrogen peroxide based Advanced Oxidation Processes combined with Hydrodynamic Cavitation
PublikacjaDecolorization of Ponceau 4R, Tartrazine, and Coomassie Brilliant Blue (CBB) was studied using hybrid processes of hydrodynamic cavitation (HC) with potassium persulfate (KPS) and hydrogen peroxide (H2O2). The different properties of these dyes such as hydrophobicity, molecular structures, and molecular weights provided this opportunity to investigate the effects of these factors by comparing the decolorization values of the dyes....
-
Interactions of telomeric proteins with nucleic acids: sequence recognition on intact and oxidatively damaged telomeres
PublikacjaTelomeres are complex nucleoprotein assemblies that play a vital role in the maintenance of functional ends of linear chromosomes. Telomeric DNA, composed of tandem repeats of the 5'-TTAGGG-3' motif, solves the so-called end replication problem: as chromosomes shorten with each cell division, no information is lost, and the telomere can be re-extended. In the cell, many protein factors regulate telomere length, nuclear positioning...
-
Social development – a multidimensional approach to social development analysis. Country level evidence.
PublikacjaThe paper constitutes an extensive analysis of level of social development in multidimensional and complex way. The study covers 144 world countries. Each country is analyzed in from the perspective of 8 non-income variables in 2011.
-
District development concept – Lower Sopot (Dolny Sopot) district case study, study proposal no 6, May 2021
Dane BadawczeThe data presents results of work within the studies of the concept of development of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 6, from May 2021. The goal of the research process was to present the development concept of the area located in Lower Sopot (Dolny Sopot) district in the context of the...
-
District development concept – Lower Sopot (Dolny Sopot) district case study, study proposal no 1, May 2021
Dane BadawczeThe data presents results of work within the studies of the concept of development of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 1, from May 2021. The goal of the research process was to present the development concept of the area located in Lower Sopot (Dolny Sopot) district in the context of the...