Wyniki wyszukiwania dla: whole-genome sequencing
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Environmentally friendly polymer-rubber composites obtained from waste tyres: A review
PublikacjaThe paper is transdisciplinary. The complex overview on changes in policy and approach to waste tyres that leads to both solving environmental problem of post consumer tyres and creating environmentally friendlier novel materials are presented. It is shown that in the world, the amount of polymer wastes increases every year. Most of them are in the form of post-consumer tyres. Recycling and recovery of such tyres is a serious environmental...
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CSR in Polish SMEs: From Perception to Love: Examples of Socially Engaged Firms from Pomeranian Region
PublikacjaNotwithstanding the worldwide increasing awareness of the importance of social issues in nowadays business management, Polish small and medium enterprises seem to remain in the group of followers, certainly not leaders of corporate social responsibility (CSR) movement, and this despite an important dissemination efforts by numerous institutions. The aim of this paper is to present the bumpy road to the implementation, still incomplete,...
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Multiple output second-generation current conveyor utilizing high frequency output stage
PublikacjaIn this paper a multiple output second-generation current conveyor (MOCCII) is presented. The main advantage of the proposed general circuit architecture over a typical structure, well known in the literature, is the use of a high passband multiple output current mplifier block instead of cascaded current mirrors. It gives similar frequency responses for all the outputs of the current conveyor and also maintains simplicity of the...
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Validation of dynamic electrochemical impedance spectrograms using autocorrelation function
PublikacjaValidation of impedance data is essential for checking the reliability of experimental data. Kramers – Kronig transformation is used to verify data obtained from classical Electrochemical Impedance Spectroscopy (EIS) measurements. Data obtained from Dynamic Electrochemical Impedance Spectroscopy (DEIS) could be validated in the same way, but in this case, there is no information about internal consistency between every single spectrum...
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Decentralized control of a different rated parallel UPS systems
PublikacjaThe paper presents the single phase uninterruptible power supply (UPS) system with galvanic separated DC-AC-DC-AC converters operating in parallel. The CAN physical layer based system of communication between converters has been developed and applied, which allow to utilize a decentralized master-slave control providing high availability factor of the whole UPS system. The control system of particular converters has been developed...
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Hybrid Method Analysis of Unshielded Guiding Structures
PublikacjaA combination of mode matching, finite element methods and generalized impedance matrix is presented in a context of propagation problems for open guiding structures. The computational domain is divided into two regions: the first one is a circular cylinder containing whole guiding structure and the second one surrounds this artificial cylinder. The impedance matrix is calculated with the use of finite element method in the first...
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Parametric analysis of Istanbul's Ring Road viaduct for three levels of seismic load
PublikacjaThe paper presents a numerical analysis of the Istanbul's ring road viaduct that is currently under construction within the Northern Marmara Highway project. The structure, due to its location on seismic prone areas is exposed to seismic loads of different magnitude and different return periods. The study is fo-cused on concrete bridge supports that are design to work in nonlinear range. The study, conducted in SOFISTIK environment,...
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Terrestrial Laser Scan and Survey Images - 3D Model - Palm House - MP1 - Leica
Dane BadawczeDataset description: Raw images from photogrammetric and terresttial laser scaning survey. Object: Palm House in Gdansk Oliwa ParkLocation: Gdansk, Pomorskie, PolandDrone type: DJI Mavic Pro 1Flight plan: Circle | Point Of InterestTarget Product: 3D ModelDate: 06.11.2018Direct georeferencing: yesMetadata data: Yes/GPSGCP: NoCamera Name: DJI FC220Lasser...
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Employee benefits in comparision to the personal payroll fund in 2017-2019 on given example
Dane BadawczeIn modern employee relations, employers offer employees a whole range of benefits, which usually are required by the relevant regulations on the part of the employer, which serve to create appropriate working conditions.
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Ocena wzmocnienia podłoża metodą wymiany dynamicznej na podstawie próbnych obciążeń kolumn
PublikacjaAnaliza wykonanego wzmocnienia słabego podłoża gruntowego pod nasyp drogowy w technologii kolumn DR na przykładzie obwodnicy Brodnicy. Omówienie warunków geotechnicznych podłoża i zastosowanych rozwiązań. Analiza wsteczna na podstawie wyników próbnych obciążeń kolumn oraz pomiarów osiadań wzmocnionego podłoża całego obszaru. Porównanie uzyskanych wyników i wnioski.
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Phenotypic consequences of the LYS4 gene disruption in Candida albicans
PublikacjaThe main scientific purpose of our studies was to verify the hypothesis that homoaconitase (HA) from Candida albicans, an enzyme catalyzing a second step of the α-aminoadipate pathway (AAP) of L-Lys biosynthesis may become a new target for antifungal chemotherapy. Previous studies indicated that the A. fumigatus mutant lacking the functional lysF gene, encoding HA, exhibited attenuated virulence in a low-dose mouse infection model...
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Comparative analysis of mRNA transcripts of HT-29 cell line expressed in identical quantities for pathogenic E. coli strains UM146 and UM147 with control Escherichia coli Nissle 1917
PublikacjaAim of study was comparative analysis of mRNA transcripts of HT-29 cell line, expressed in identical quantities for the combination of pathogenic and non-pathogenic Escherichia coli strains. HT-29 confluent monolayers infection with two pathogenic E. coli strains UM146 and UM147 resulted in two sets of mRNA transcripts that were identical with RNA transcripts obtained for non-pathogenic one strain E. coli Nissle 1917. In this study...
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Molecular Dynamics to Predict Cryo-EM: Capturing Transitions and Short-Lived Conformational States of Biomolecules
PublikacjaSingle-particle cryogenic electron microscopy (cryo-EM) has revolutionized the field of the structural biology, providing an access to the atomic resolution structures of large biomolecular complexes in their near-native environment. Today’s cryo-EM maps can frequently reach the atomic-level resolution, while often containing a range of resolutions, with conformationally variable regions obtained at 6 Å or worse. Low resolution...
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Bortezomib induces methylation changes in neuroblastoma cells that appear to play a significant role in resistance development to this compound
PublikacjaThe anticancer activity of bortezomib (BTZ) has been increasingly studied in a number of indications and promising results for the use of this treatment have been shown in neuroblastoma. As BTZ treatment is usually administered in cycles, the development of resistance and side effects in patients undergoing therapy with BTZ remains a major challenge for the clinical usage of this compound. Common resistance development also means...
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Determination of Vehicles Load Equivalency Factors for Polish Catalogue of Typical Flexible and Semi-rigid Pavement Structures
PublikacjaThe new Polish Catalog of Typical Flexible and Semi-rigid Pavement Structures was introduced to use in practice in 2014. Much of works were focused on actualization of vehicles load equivalency factors. For this purpose data delivered from weigh-inmotion were analyzed. Four methods of determination of load equivalency factors for pavement structure design were compared. The analysis showed that fourth power equation, AASHTO 1993...
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The first study on the usefulness of recombinant tetravalent chimeric proteins containing fragments of SAG2, GRA1, ROP1 and AMA1 antigens in the detection of specific anti-Toxoplasma gondii antibodies in mouse and human sera
PublikacjaThis study presents an evaluation of four tetravalent recombinant chimeric proteins containing fragments of the Toxoplasma gondii antigens, SAG2, GRA1, ROP1 and AMA1, as potential replacements of a the soluble, whole-cell tachyzoite lysate (TLA) used in serological assays. Recombinant chimeric proteins (SAG2-GRA1-ROP1-AMA1N, AMA1N-SAG2-GRA1-ROP1, AMA1C-SAG2-GRA1-ROP1, and AMA1-SAG2-GRA1-ROP1) obtained by genetic engineering were...
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Analysis of energy efficiency of suburban railway transport network
PublikacjaRising numbers of agglomeration residents cause increased need for people movement on daily basis. Because of congestion of local roads, air pollution and limited parking space, providing mass transit based on electric traction is reasonable. While the electric rail vehicles are considered highly efficient in themselves, they need to be analyzed as a part of a transport network, because energy consumption depends on operating conditions...
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Interactive and Media Architecture – From Social Encounters to City Planning Strategies
PublikacjaThe paper searches into the potential of media and interactive projects to support participation and generate social encounters in public spaces. Moreover, it proposes implementation of media and interactive projects into city planning processes. On the basis of theoretical approaches, case studies and interdisciplinary surveys the paper gives insight how interactive and media architecture can engage people in activities in urban...
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Дослідження проблем зайнятості випускників навчальних закладів
PublikacjaУ зв'язку зі зниженням загального рівня зайнятості та з огляду на кризові явища в українській економіці актуальною залишається проблема працевлаштування молоді. Спільність проблеми зайнятості випускників вишів як в Україні, так і в Європі дала змогу провести міжнародне дослідження, щоб виявити основні причини її виникнення. Результати досліджень підтвердили гіпотезу авторів. В її основі лежить комплекс причин, що пов’язані як зі...
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ROZPROSZONY SYSTEM KOMUNIKACJI I NADZORU DLA MORSKIEGO ODDZIAŁU STRAŻY GRANICZNEJ – PROJEKT STRADAR
PublikacjaSystem STRADAR to wynik realizacji projektu, którego gestorem jest MO SG. Był on współfinansowany przez NCBiR. W artykule opisano system, przedstawiając ogólną koncepcję, architekturę, elementy funkcjonalne i realizację oprogramowania zainstalowanego w tych elementach. Krótko scharakteryzowano także testy, jakim poddano system, który na tym etapie – jako całość – osiągnął VII poziom gotowości technologii.
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Testing HIADAC high impedance analyzer in Trento University laboratory on Baunier's RC model using 2 wire probe
Dane BadawczeThe dataset presents impedance spectrum of Baunier's RC model. This object was used to test high-impedance analyzer for diagnostic of anticorossion coatings (HIADAC) realized in the frame of Eureka project E!3174. The impedance spectrum frequency range (1 mHz – 100 kHz) was selected in order to test the whole measureement range of the analyzer. In...
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Quantum-state transfer in spin chains via isolated resonance of terminal spins
PublikacjaWe propose a quantum-state transfer protocol in a spin chain that requires only the control of the spins at the ends of the quantum wire. The protocol is to a large extent insensitive to inhomogeneity caused by local magnetic fields and perturbation of exchange couplings. Moreover, apart from the free evolution regime, it allows one to induce an adiabatic spin transfer, which provides the possibility of performing the transfer...
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Does source matter? Generation of investment expenditures by different types of local government revenues
PublikacjaThe purpose of the article was to investigate the impact of the three fundamental statutory categories of budget revenues, i.e. own revenues, general subsidies and specific grants on the size of investments made by local government units in Poland. The subject scope included the local government subsector in its entirety, as well as divided into 4 groups: communes (gminas), cities with powiat rights, districts (powiats) and province...
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Relationship between semi- and fully-device-independent protocols
PublikacjaWe study the relation between semi and fully device independent protocols. As a tool, we use the correspondence between Bell inequalities and dimension witnesses. We present a method for converting the former into the latter and vice versa. This relation provides us with interesting results for both scenarios. First, we find new random number generation protocols with higher bit rates for both the semi and fully device independent...
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Balancing agility and discipline in a research project
PublikacjaSuccessful software development requires both agility and discipline. Optimal selection of methods, however, is not an easy task. The problem becomes even more difficult for long lasting projects. Appropriate selection of methods involving skillful introduction and abandonment of certain practices in time makes the whole process dynamic. The paper presents in this context a research project which was realized in a few iterations....
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Dipole-driven dynamics for near-threshold electron/positron interactions with pyrimidinic DNA bases: a path to compound formations
PublikacjaCalculations are reported for electron and positron scattering from isolated cytosine and thymine, where the two pyrimidinic single-ring DNA bases, in the gas-phase at energies near the elastic threshold, they reveal the special features of the dipole-driven scattering states. All molecules examined exhibit, in fact, supercritical (>1.67 D) permanent dipoles which can therefore also support, below threshold, excited bound compound...
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The propagation of the waves in the CTO S.A. towing tank
PublikacjaThe paper presents the results of research focused on the wave propagation in the CTO S.A. deepwater towing tank. In the scope of paper, the wavemaker transfer function was determined for regular waves, based on the Biésel Transfer Function and further for irregular waves, based on Hasselman model of nonlinear energy transfer. The phenomena: wave damping, wave breakdown and wave reflection, were measured, analyzed and mathematically...
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Review on the quality of sediments from the stormwater drainage system in the urban area
PublikacjaThe main task of the stormwater drainage system is a safe drainage of rainwater and snowmelt from the urban area to the receiver. The flow of rain water in the drainage pipes is directly related with the formation of sediments in the whole stormwater system. In addition, pollutants from land runoff get adsorbed to the sediments. The sludge is mainly formed in those elements of stormwater drainage system, wherein the flow conditions...
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Importance of the combined effects of dissolved oxygen and pH on optimization of nitrogen removal in anammox-enriched granular sludge
PublikacjaThe combined effects of dissolved oxygen (DO) and pH on nitrogen removal were investigated in a laboratory-scale sequencing batch reactor (SBR) with anammox-enriched granular sludge obtained from a nitritation/anammox system. The highest specific nitrogen removal rate (SNRR) (1.1 gN gVSS−1 d−1) was observed under non-aerated conditions, resulting in the nitrogen removal efficiency of 81.6%. Although nitrogen removal was readily...
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The effects of different aeration modes on ammonia removal from sludge digester liquors in the nitritation–anammox proces
PublikacjaThe aim of this study was to determine the impact of continuous and intermittent aeration on the rate of ammonia removal in the combined nitritation–anammox process. This process was run in two parallel sequencing batch reactors (SBRs), with a working volume V = 10 L, treating sludge digester liquors from the Gdansk (Poland) wastewater treatment plant (WWTP). The ammonia oxidizing bacteria were cultivated from activated sludge...
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Personalized prediction of the secondary oocytes number after ovarian stimulation: A machine learning model based on clinical and genetic data
PublikacjaControlled ovarian stimulation is tailored to the patient based on clinical parameters but estimating the number of retrieved metaphase II (MII) oocytes is a challenge. Here, we have developed a model that takes advantage of the patient’s genetic and clinical characteristics simultaneously for predicting the stimulation outcome. Sequence variants in reproduction-related genes identified by next-generation sequencing were matched...
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Diagnostic Accuracy of Liquid Biopsy in Endometrial Cancer
PublikacjaBackground: Liquid biopsy is a minimally invasive collection of a patient body fluid sample. In oncology, they offer several advantages compared to traditional tissue biopsies. However, the potential of this method in endometrial cancer (EC) remains poorly explored. We studied the utility of tumor educated platelets (TEPs) and circulating tumor DNA (ctDNA) for preoperative EC diagnosis, including histology determination. Methods:...
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Evaluation of Partial Nitritation/Anammox (PN/A) Process Performance and Microorganisms Community Composition under Different C/N Ratio
PublikacjaA one-stage partial nitritation/anammox (PN/A) process with intermittent aeration is possible under sidestream conditions, but implementation in a mainstream is a challenge due to increased Carbon/Nitrogen (C/N) ratios in domestic wastewater. This study investigated the effect of C/N ratios on process efficiency and the effect of narrowing non-aeration time on process improvement at high chemical oxygen demand (COD) load. An increase...
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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublikacjaAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...
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Achieving Efficient and Stable Deammonification at Low Temperatures—Experimental and Modeling Studies
PublikacjaThe short-term effects of temperature on deammonification sludge were evaluated in a laboratory-scale sequencing batch reactor (SBR). Mathematical modeling was used for further evaluations of different intermittent aeration strategies for achieving high and stable deammonification performance at decreasing temperatures. As for the biomass cultivated at high temperatures (e.g., 30 C), a higher temperature dependency (the adjusted...
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Paenibacillus alvei MP1 as a Producer of the Proteinaceous Compound with Activity against Important Human Pathogens, Including Staphylococcus aureus and Listeria monocytogenes
PublikacjaAn emerging need for new classes of antibiotics is, on the one hand, evident as antimicrobial resistance continues to rise. On the other hand, the awareness of the pros and cons of chemically synthesized compounds’ extensive use leads to a search for new metabolites in already known reservoirs. Previous research showed that Paenibacillus strain (P. alvei MP1) recovered from a buckwheat honey sample presented a wide spectrum of...
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Bacterial Community Structures in Freshwater Polar Environments of Svalbard
PublikacjaTwo thirds of Svalbard archipelago islands in the High Arctic are permanently covered with glacial ice and snow. Polar bacterial communities in the southern part of Svalbard were characterized using an amplicon sequencing approach. A total of 52,928 pyrosequencing reads were analyzed in order to reveal bacterial community structures in stream and lake surface water samples from the Fuglebekken and Revvatnet...
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CERVIX UTERI, Exocervix - Female, 36 - Cell image [7050730000137891]
Dane BadawczeThis is the histopathological image of CERVIX UTERI cell sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Colon, unspecified - Female, 76 - Tissue image [4260730038471311]
Dane BadawczeThis is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Colon, unspecified - Female, 76 - Tissue image [4260730038475251]
Dane BadawczeThis is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Testing impedance analyzer with potentiostat using RC model with Si diode at 200 mV
Dane BadawczeThe dataset presents impedance spectrum non-linear RC model with diode presented in the figure below. This model was used as a test engine of the impedance analyzer with potentiostat described in the referenced paper. When changing the DC polarisation of the model the non-linear phenomena could be observed. Thanks to this, the model can be used as a...
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Testing impedance analyzer with potentiostat using RC model with Si diode at 0 V
Dane BadawczeThe dataset presents impedance spectrum non-linear RC model with diode presented in the figure below. This model was used as a test engine of the impedance analyzer with potentiostat described in the referenced paper. When changing the DC polarisation of the model the non-linear phenomena could be observed. Thanks to this, the model can be used as a...
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Testing impedance analyzer with potentiostat using RC model with Si diode at 600 mV
Dane BadawczeThe dataset presents impedance spectrum non-linear RC model with diode presented in the figure below. This model was used as a test engine of the impedance analyzer with potentiostat described in the referenced paper. When changing the DC polarisation of the model the non-linear phenomena could be observed. Thanks to this, the model can be used as a...
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Testing impedance analyzer with potentiostat using RC model with Si diode at 400 mV
Dane BadawczeThe dataset presents impedance spectrum non-linear RC model with diode presented in the figure below. This model was used as a test engine of the impedance analyzer with potentiostat described in the referenced paper. When changing the DC polarisation of the model the non-linear phenomena could be observed. Thanks to this, the model can be used as a...
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Testing HIADAC high impedance analyzer in Trento University laboratory on Baunier's RC model using 3 wire probe
Dane BadawczeThe dataset presents impedance spectrum of Baunier's RC model. This object was used to test high-impedance analyzer for diagnostic of anticorossion coatings (HIADAC) realized in the frame of Eureka project E!3174. The impedance spectrum frequency range (1 mHz – 100 kHz) was selected in order to test the whole measureement range of the analyzer. In...
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Testing HIADAC high impedance analyzer in Trento University laboratory on "unknown" object using 2-wire probe
Dane BadawczeThe dataset presents impedance spectrum of "black-box" object with interesting phase characteristics. This object was used to test high-impedance analyzer for diagnostic of anticorossion coatings (HIADAC) realized in the frame of Eureka project E!3174. The impedance spectrum frequency range (1 Hz – 100 kHz) was selected in order to test the whole measureement...
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Gas boiler as a heat source for the domestic micro-CHP
PublikacjaThis analysis considers a commercially available domestic gas boiler as a heat source for a domestic organic Rankine cycle system. An experimental study was made into the applicability of the gas boiler (De Dietrich with thermal power 25 kW) coupled with the laboratory prototype micro ORC setup. The main aim of the study is to determine the working fluid temperature, attainable heat rates and effciencies of the whole system. Preliminary...
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Passing from requirements specification to class model using application domain ontology
PublikacjaThe quality of a classic software engineering process depends on the completeness of project documents and on the inter-phase consistency. In this paper, a method for passing from the requirement specification to the class model is proposed. First, a developer browses the text of the requirements, extracts the word sequences, and places them as terms into the glossary. Next, the internal ontology logic for the glossary needs to...
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Loop-mediated isothermal amplification (LAMP) as a diagnostic tool in detection of infectious diseases
PublikacjaLoop-mediated isothermal amplification (LAMP) is a gene amplification method which amplifies DNA with high specificity and efficiency under isothermal conditions. Because of its rapidity and simplicity, it is a valuable diagnostic tool in the early detection and identification of infectious diseases. LAMP method is based on the use of a set of four to six specially designed primers spanning six to eight distinct sequences on the...
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Gas boiler as a heat source for the domestic micro-CHP
PublikacjaIn the presented analysis a commercially available domestic gas boiler as a heat source for domestic ORC is considered. The applicability of the gas boiler (De Dietrich with thermal power 25 kW) coupled with the laboratory prototype micro ORC setup has experimentally studied. The main aim of the study is to determine the working fluid temperature, attainable heat rates and efficiencies of the whole system. Preliminary investigations...