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Wyniki wyszukiwania dla: PSORIASIS GENETICS, GWAS, EPIGENETIC CHANGES, MIRNA
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Changes in Eating Behaviour during SARS-CoV-2 Pandemic among the Inhabitants of Five European Countries
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Across-Shift Changes in Viable Nasal Bacteria among Waste-Incineration Plant Workers—A Pilot Study
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Dynamics of changes in the concentration levels of organic pollutants in the proglacial waters of the Scott River (Spitsbergen, SW Svalbard)
PublikacjaThe study area covered the NW part of the Wedel Jarlsberg Land. The present study concerns participation of organic pollutants inflow from glacier and seaside plane of Calypsostranda to proglacial waters of the Scott River due to occurrence of precipitation. Concentration ranges for phenols and formaldehyde in water samples are respectively:
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New approach to noncausal identification of nonstationary stochastic systems subject to both smooth and abrupt parameter changes
PublikacjaIn this paper we consider the problem of finiteintervalparameter smoothing for a class of nonstationary linearstochastic systems subject to both smooth and abrupt parameterchanges. The proposed parallel estimation scheme combines theestimates yielded by several exponentially weighted basis functionalgorithms. The resulting smoother automatically adjustsits smoothing bandwidth to the type and rate of nonstationarityof the identified...
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Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression
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Metamorphosis-related changes in the free fatty acid profiles of Sarcophaga (Liopygia) argyrostoma (Robineau-Desvoidy, 1830)
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Soil organic carbon, macro- and micronutrient changes in soil fractions with different lability in response to crop intensification
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Efficiency of optical-electronic systems: methods application for the analysis of structural changes in the process of eye grounds diagnosis
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Changes in enzymatic activity of fish and slaughter animals meat after high pressure treatment at subzero temperatures
PublikacjaThe aim of this study was to determine changes in the activity of proteolytic enzymes and transglutaminase of fish and mammal meat after pressurization at subzero temperatures. The activity was measured at the optimal pHs determined for enzymes from particular types of tested meat. It was found that increasing the pressure in the range of 60–193 MPa, did not change significantly the activity of acidic proteases of cod flesh, while...
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The changes of crosslink density of polyurethanes synthesised with using recycled component. Chemical structure and mechanical properties investigations.
PublikacjaThis paper aims at the utilisation of glycerolysate (Gly) obtained in polyurethane recycling process by means of crude glycerine, which has in its structure hydroxyl end groups that allow for further processing. Polyurethanes (PUs) were synthesised using prepolymer method with the mixture of neat polyol and glycerolysate, in different ratios, with 4,4-diphenylmethane diisocyanate (MDI). The prepolymer was subsequently extended...
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Geochemical Changes in Aquatic Environment Caused by Deep Dredging - A Case Study: The Puck Bay (Baltic Sea)
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Direction of Changes in the Settlements for Prosumers of Photovoltaic Micro-Installations: The Example of Poland as the Economy in Transition in the European Union
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Gene and Protein Accumulation Changes Evoked in Porcine Aorta in Response to Feeding with Two Various Fructan Sources
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Proteome changes in renal cortex and medulla induced by dietary supplementation with inulin‐type fructans in growing pigs
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Simulation of the number of storm overflows considering changes in precipitation dynamics and the urbanisation of the catchment area: a probabilistic approach
PublikacjaThis paper presents a probabilistic methodology that allows the study of the interactions between changes in rainfall dynamics and impervious areas in urban catchment on a long- and short-term basis. The proposed probabilistic model predict future storm overflows while taking into account the dynamics of changes in impervious areas and rainfall. In this model, a logistic regression method was used to simulate overflow resulting...
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Hepatic proteome changes induced by dietary supplementation with two levels of native chicory inulin in young pigs
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CHANGES IN SELECTED CHEMICAL AND MICROBIOLOGICAL INDICATORS DURING WARM SMOKING PROCESS OF THAWED WHITEFISH (COREGONIS CLUPEAFORMIS)
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The latest Jurassic–earliest Cretaceous climate and oceanographic changes in the Western Tethys: The Transdanubian Range (Hungary) perspective
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Impedance plethysmography as a tool for assessing exertion-related blood flow changes in the lower limbs in healthy subjects
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Bortezomib induces methylation changes in neuroblastoma cells that appear to play a significant role in resistance development to this compound
PublikacjaThe anticancer activity of bortezomib (BTZ) has been increasingly studied in a number of indications and promising results for the use of this treatment have been shown in neuroblastoma. As BTZ treatment is usually administered in cycles, the development of resistance and side effects in patients undergoing therapy with BTZ remains a major challenge for the clinical usage of this compound. Common resistance development also means...
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Structural changes of bacterial cellulose due to incubation in conditions simulating human plasma in the presence of selected pathogens
PublikacjaBacterial nanocellulose (BNC) is a natural biomaterial with a wide range of medical applications. However, it cannot be used as a biological implant of the circulatory system without checking whether it is biodegradable under human plasma conditions. This work aimed to investigate the BNC biodegradation by selected pathogens under conditions simulating human plasma. The BNC was incubated in simulated biological fluids with or...
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Changes of microbiological quality of water in distribution system. Zmiany mikrobiologicznej jakości wody w sieci dystrybucyjnej.
PublikacjaW artykule przedstawiono mikrobiologiczną jakość wody podziemnej uzdatnianej w dwóch stacjach oczyszczania wody (WTP I i WTP II), w sieci dystrybucyjnej. Obie stacje uzdatniania stosują dezynfekcję za pomocą dwutlenku chloru. Badania wykazały wzrost ogólnej liczby bakterii w miarę zwiększania się odległości od stacji uzdatniania.In the paper microbiological quality of water in distribution system produced in two ground water treatment...
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Using UAV Photogrammetry to Analyse Changes in the Coastal Zone Based on the Sopot Tombolo (Salient) Measurement Project
PublikacjaThe main factors influencing the shape of the beach, shoreline and seabed include undulation, wind and coastal currents. These phenomena cause continuous and multidimensional changes in the shape of the seabed and the Earth’s surface, and when they occur in an area of intense human activity, they should be constantly monitored. In 2018 and 2019, several measurement campaigns took place in the littoral zone in Sopot, related to...
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Effect of mean grain diameter on vortices, force chains and local volume changes in granular shear zones
PublikacjaW artykule pokazano rozwój różnych zjawisk mikrostrukturalnych na poziomie ziarna materiału granulowanego podczas parcia pasywnego piasku na sztywną ściankę przemieszczającą się poziomo. Obliczenia wykonano stosując metodę DEM. Wyniki na poziomie globalnym porównano z wynikami MES. Szczególna uwagę zwrócono na rozwój wirów i łańcuchów sił miedzy ziarnami.
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Quantitative estimation of volume changes of granular materials during silo flow using X-ray tomography.
PublikacjaW artykule przedstawiono wyniki badań doświadczalnych nad zmianami objętościowymi materiału granulowanego podczas przepływu silosowego. Badania wykonano przy zastosowaniu tomografii rentgenowskiej. Wyniki porównano z wynikami doświadczalnymi przy zastosowaniu cyfrowej obróbki zdjęć płynącego materiału.
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Evaluation of the significance of the effect of the active cross-sectional area of the inlet air channel on the specific enthalpy of the exhaust gas of a diesel engine using statistics F of the Fisher-Snedecor distribution
PublikacjaThis paper presents the application of Fisher-Snedecor distribution F statistics to assess the significance of the influence of changes in the active cross-sectional area of the inlet air channel (Adol) flow in a diesel engine on the observed diagnostic parameter determined on the basis of measurements of the quick changing exhaust gas temperature in the outlet channel, which is the specific enthalpy of the exhaust gas stream within...
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The effect of oxidized cholesterol on barrier functions and IL-10 mRNA expression in human intestinal epithelium co-cultured with dendritic cells in the transwell system
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Thermal degradation kinetics of poly(propylene succinate) prepared with the use of natural origin monomers
PublikacjaLinear biobased polyester polyols were prepared with the use of succinic acid and 1,3-pro- panediol (both with natural origin). Tetraisopropyl orthotitanate (TPT) was used as a catalyst. In order to determine the effect of various synthesis temperature conditions on the thermal degradation kinet- ics, nine sequences of temperature conditions were used during two-step polycondensation reaction. Thermogravimetric analysis was conducted...
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The application of Monod equation to denitrification kinetics description in the moving bed biofilm reactor (MBBR)
PublikacjaIn this paper, the kinetic constants Vmax and KCOD occurring in the Monod equation, which describe the denitrification process in the moving bed, are determined. For this purpose, a laboratory moving bed biofilm reactor (MBBR) was used. The filling of the reactor consisted of EvU Perl carriers. The experiment was carried out with an excess of nitrate, and denitrification rate was dependent on the concentration of external organic...
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Tb3+ ions in the presence of ZnS:Mn2+ nanocrystals incorporated into silica: Tb3+ and Mn2+ luminescence kinetics
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Decomposition of xenobiotics during visible light irradiation in the presence of immobilised photosensitisers: kinetics study
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Effects of the polyhistidine tag on kinetics and other properties of trehalose synthase from Deionococcus geothermalis
PublikacjaTwo recombinant trehalose synthases from Deinococcus geothermalis (DSMZ 11300) were compared. A significant influence of the artificial polyhistidine tag was observed in protein constitution. The recombinant trehalose synthase from D. geothermalis with His6 -tag has a higher K m value of 254 mM, in comparison with the wild-type trehalose synthase (K m 170 mM), and displayed a lower activity of maltose conversion when compared...
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Fractional neutron point kinetics equations for nuclear reactor dynamics – Numerical solution investigations
PublikacjaThis paper presents results concerning numerical solutions to a fractional neutron point kinetics model for a nuclear reactor. The paper discusses and expands on results presented in (Espinosa-Paredes et al., 2011). The fractional neutron point kinetics model with six groups of delayed neutron precursors was developed and a numerical solution using the Edwards’ method was proposed (Edwards et al., 2002). The mathematical model...
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Salt melt synthesis of curved nitrogen-doped carbon nanostructures: ORR kinetics boost
PublikacjaImplementing metal-free electrocatalysts for the oxygen reduction reaction (ORR) and revealing crucial chemical or topographical parameters driving their activity are vital for the development of power cells. The carbon-based catalysts are very often synthesized through carbonization of biopolymers, in particular, those one containing nitrogen groups such as chitosan. Unfortunately, the resulting carbonaceous materials usually...
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Thermodynamics and kinetics of amphotericin B self-association in aqueous solution characterized in molecular detail
PublikacjaAmphotericin B (AmB) is a potent but toxic drug commonly used to treat systemic mycoses. Its efficiency as a therapeutic agent depends on its ability to discriminate between mammalian and fungal cell membranes. The association of AmB monomers in an aqueous environment plays an important role in drug selectivity, as oligomers formed prior to membrane insertion – presumably dimers – are believed to act differently on fungal (ergosterol-rich)...
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Kinetics of Intermetallic Phase Precipitation in Manual Metal Arc Welded Duplex Stainless Steels
PublikacjaThe article presents the influence of heat treatment on the kinetics of transformations in lean duplex LDX2101 steel and a weld made of standard duplex 2209 material, which was welded by manual metal arc welding. Changes in the microstructure, hardness, and magnetic phase content were analyzed after heat treatment was conducted at a temperature of 800 °C for a period ranging from 15 to 1440 min. Light and scanning microscopy, Vickers...
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Screening stability, thermochemistry, and chemical kinetics of 3-hydroxybutanoic acid as a bifunctional biodiesel additive
PublikacjaThe thermo-kinetic aspects of 3-hydroxybutyric acid (3-HBA) pyrolysis in the gas phase were investigated using density functional theory (DFT), specifically the M06-2X theoretical level in conjunction with the cc-pVTZ basis set. The obtained data were compared with benchmark CBS-QB3 results. The degradation mechanism was divided into 16 pathways, comprising 6 complex fissions and 10 barrierless reactions. Energy profiles were calculated...
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Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines
PublikacjaThe epoxy/clay nanocomposites have been extensively considered over years because of their low cost and excellent performance. Halloysite nanotubes (HNTs) are unique 1D natural nanofillers with a hollow tubular shape and high aspect ratio. To tackle poor dispersion of the pristine halloysite (P-HNT) in the epoxy matrix, alkali surface-treated HNT (A-HNT) and epoxy silane functionalized HNT (F-HNT) were developed and cured with...
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Kinetics of Cross-Linking Reaction of Epoxy Resin with Hydroxyapatite-Functionalized Layered Double Hydroxides
PublikacjaThe cure kinetics analysis of thermoset polymer composites gives useful information about their properties. In this work, two types of layered double hydroxide (LDH) consisting of Mg2+ and Zn2+ as divalent metal ions and CO32− as an anion intercalating agent were synthesized and functionalized with hydroxyapatite (HA) to make a potential thermal resistant nanocomposite. The curing potential of the synthesized nanoplatelets in the...
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Population dynamics of Baltic herring since the Viking Age revealed by ancient DNA and genomics
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Comparative Genomics of Stenotrophomonas maltophilia and Stenotrophomonas rhizophila Revealed Characteristic Features of Both Species
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Understanding the kinetics and atmospheric degradation mechanism of chlorotrifluoroethylene (CF2=CFCl) initiated by OH radicals
PublikacjaThe atmospheric degradation of chlorotrifluoroethylene (CTFE) by OH˙ was investigated using density functional theory (DFT). The potential energy surfaces were also defined in terms of single-point energies derived from the linked cluster CCSD(T) theory. With an energy barrier of −2.62 to −0.99 kcal mol−1 using the M06-2x method, the negative temperature dependence was determined. The OH˙ attack on Cα and Cβ atoms (labeled pathways...
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New oryginal generic technologies: A Polish R&D strategic implementation programme
PublikacjaPolands's pharmaceutical industry is of great significance to the whole economy. According to Forbs (2 October 2012), the cost of launching a new drug varies from USD 1 to 11 bilion. There is little Chance of a Polish pharmaceutical company developing an original drug due to financial reason.Many research teams in Poland take up research projects aimed at new biologically active compounds. But such an objective has no broader perspective,...
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Genetic and biochemical determinants of serum concentrations of monocyte chemoattractant protein-1, a potential neural tube defect risk factor
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Morphological and molecular genetic diversity analysis using SSR markers in Jackfruit (Artocarpus heterophyllus Lam.) genotypes for pulp colour
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Personalized prediction of the secondary oocytes number after ovarian stimulation: A machine learning model based on clinical and genetic data
PublikacjaControlled ovarian stimulation is tailored to the patient based on clinical parameters but estimating the number of retrieved metaphase II (MII) oocytes is a challenge. Here, we have developed a model that takes advantage of the patient’s genetic and clinical characteristics simultaneously for predicting the stimulation outcome. Sequence variants in reproduction-related genes identified by next-generation sequencing were matched...
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Fingerprinting, structure, and genetic relationships among selected accessions of blue honeysuckle (Lonicera caerulea L.) from European collections
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Carbon dioxide ocean and ground storage as a method of climate change mitigation
PublikacjaW pracy dokonano krytycznego przeglądu negatywnego wpływu globalnego ocieplenia na środowisko i przedstawiono dwie nowatorskie metody zmniejszenia stężenia atmosferycznego ditlenku węgla. Obie metody: magazynowanie antropogenicznego ditlenku węgla, pochodzącego z dużych źródeł emisji, w oceanach i w glebie są technologicznie możliwe do przeprowadzenia, co potwierdzają przykłady z różnych regionów świata. W pracy przedyskutowano...
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Analysis of the torque response of a car engine to the step change of the control signal
PublikacjaW pracy zamieszczono wyniki badań silnika samochodu osobowego w warunkach nieustalonych. Stan obciążenia silnika wynikał z realizowanego cyklu jezdnego w warunkach drogowych oraz sposobu sterowania układem napędowym. Parametry trakcyjne pojazdu mierzone były za pomocą systemu GPS z fenomenologiczną korektą sygnału wysokości, na której się on znajdował. Wybrane parametry pracy silnika mierzone były za pomocą sytemu komunikującego...
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Economic growth, structural change and quality upgrading in New Member States
PublikacjaThe purpose of this research is to present the recent developments concerning structural change and productivity growth in New Member States and the role played in such process by country specific factors. We focus on ten countries (NMS-10) which joined the EU in 2004 and analyze productivity dynamics of their labor structures between the years 1995 and 2005 in a comparative setting versus EU-15 economies. NMS-10 have gone through...