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Wyniki wyszukiwania dla: HUMAN BIOFLUIDS
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3-Monochloropropane-1,2-diol in Infant Foods and Human Breast Milk: Determination by GC-MS
Publikacja3-Monochloropropane-1,2-diol is one of the food borne contaminants called chloropropanols. Over the last decade plenty of analytical methods was developed in order to determine 3-monochloropropane-1,2-diol in its free and bound form in various foodstuffs with the use of GC-FID, GC-ECD, LC-TOFMS and finally GC-MS, which is now widely used in laboratories. The aim of this research was the determination of 3-monochloropropane--1,2-diol...
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Human sperm proteins identified by 2-dimensional electrophoresis and mass spectrometry and their relevance to a transcriptomic analysis
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Preferred Benchmarking Criteria for Systematic Taxonomy of Embedded Platforms (STEP) in Human System Interaction Systems
PublikacjaThe rate of progress in the field of Artificial Intelligence (AI) and Machine Learning (ML) has significantly increased over the past ten years and continues to accelerate. Since then, AI has made the leap from research case studies to real production ready applications. The significance of this growth cannot be undermined as it catalyzed the very nature of computing. Conventional platforms struggle to achieve greater performance...
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Computer-Aided Greenery Design—Prototype Green Structure Improving Human Health in Urban Ecosystem
PublikacjaIncreasing population and urbanization, with climate change consequences, such as rising temperatures, influence public health and well-being. The search to improve the quality of life in cities becomes one of the priority objectives. A solution can be found in the role of greenery in an urban environment and its impact on human health. This opens a path toward experimentation on microclimate green structures that can be inserted...
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A novel in vivo approach to assess strains of the human abdominal wall under known intraabdominal pressure
PublikacjaThe study concerns mechanical behaviour of a living human abdominal wall. A better mechanical understanding of a human abdominal wall and recognition of its material properties is required to find mechanically compatible surgical meshes to significantly improve the treatment of ventral hernias. A non-invasive methodology, based on in vivo optical measurements is proposed to determine strains of abdominal wall corresponding to...
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In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
PublikacjaBACKGROUND. Noninvasive assessment of metabolic processes that sustain regeneration of human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics and to accelerate development of new treatments to counter retinal diseases. Fluorescent vitamin A derivatives, which are the chemical intermediates of these processes, are highly sensitive to UV light; thus, safe analyses of these processes in humans...
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Validation of Hydraulic Mechanism during Blowout Trauma of Human Orbit Depending on the Method of Load Application
PublikacjaThe more we know about mechanisms of the human orbital blowout type of trauma, the better we will be able to prevent them in the future. As long as the buckling mechanism’s veracity is not in doubt, the hydraulic mechanism is not based on equally strong premises. To investigate the correctness of the hydraulic mechanism’s theory, two different methods of implementation of the hydraulic load to the finite element method (FEM) model...
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Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
PublikacjaObjective: Our goal was to analyze the electrophysiological response to direct electrical stimulation (DES) systematically applied at a wide range of parameters and anatomical sites, with particular focus on neural activities associated with memory and cognition. Methods: We used a large set of intracranial EEG (iEEG) recordings with DES from 45 subjects with electrodes...
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Social Capital, Human Capital, Tacit Knowledge, and Innovations: A Polish-US Cross-Country Study
PublikacjaThis study measures the relationship between human and social capital (internal and external) and tacit knowledge sharing's influence on innovativeness among knowledge workers employed in Polish (n=1050) and US (n=1118) organizations. The structural equation modeling method revealed that internal social capital matters more for organizational innovativeness in the US. In Poland, both external and internal were important. Specifically,...
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The influence of Nigella sativa essential oil on proliferation, activation, and apoptosis of human T lymphocytes in vitro
PublikacjaIn previous work, we tested the immunomodulatory effect of Nigella sativa (NS) fatty oil. Our results demonstrated that unrefined, obtained by cold pressing black cumin seed oil inhibited lymphocytes’ proliferation and induced their apoptosis in a dose-dependent manner. In this study, we examined the immunomodulatory properties of essential oil (EO) obtained from the NS seeds by hydrodistillation and its two main constituents:...
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Nonlinear dynamic analysis of the pure “buckling” mechanism during blow-out trauma of the human orbit
PublikacjaConsidering the interplay between orbital bones and intraorbital soft tissues, commonly accepted patterns of the blow-out type of trauma within the human orbit require more thorough investigation to assess the minimal health-threatening impact value. Two different three-dimensional finite element method (FEM) models of the human orbital region were developed to simulate the pure “buckling” mechanism of orbital wall fracture in...
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Multifactor consciousness level assessment of participants with acquired brain injuries employing human–computer interfaces
PublikacjaBackground A lack of communication with people suffering from acquired brain injuries may lead to drawing erroneous conclusions regarding the diagnosis or therapy of patients. Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the...
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Long‐time scale simulations of virus‐like particles from three human‐norovirus strains
PublikacjaThe dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause gastroenteritis was investigated by means of long-time (about 30 μs in the laboratory timescale) molecular dynamics simulations with the coarse-grained UNRES force field. The main motion of VLP units turned out to be the bending at the junction between the P1 subdomain (that...
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Evidence for consolidation of neuronal assemblies after seizures in humans
PublikacjaThe establishment of memories involves reactivation of waking neuronal activity patterns and strengthening of associated neural circuits during slow-wave sleep (SWS), a process known as "cellular consolidation" (Dudai and Morris, 2013). Reactivation of neural activity patterns during waking behaviors that occurs on a timescale of seconds to minutes is thought to constitute memory recall (O'Keefe and Nadel, 1978), whereas consolidation...
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Oxidative stress in humans: validation of biomarkers of DNA damage
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What defines excellent lighting design for humans and animals?
PublikacjaWhat defines excellent lighting design for humans and animals? The answer to the above question is more than complex. It is not enough nowadays to design a project to make it aesthetically pleasing. Nor is it sufficient to create nicely lit environments, or simply to achieve the light levels required by the lighting norms or standards. With the new scientific research of the last few decades that relates directly or indirectly...
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Olfactory and tissue markers of fear in mammals including humans
PublikacjaW pracy przedstawiono informacje na temat:-klasyfikacji i budowy chemicznej związków chemicznych zaliczanych do grupy feromonów,-ich rola w funkcjonowaniu organizmów żywych w tym także organizmu ludzkiego,wyników badań prowadzonych z wykorzystaniem komory ekspozycyjnej własnej konstrukcji,metodyk analitycznych wykorzystywanych do oznaczania śladowych zawartości feromonów w próbkach wydychanego powietrza.
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A study to identify olfactory markers of fear in rats and humans
PublikacjaW pracy przedstawiono wyniki wstępnych badań ukierunkowanych na wykrycie podstawowych fermonów wydzielanych w sytuacji zagrożenia (fermony alarmowe) przez różne organizmy żywe.W badaniach zastosowano takie techniki jak TD-GC-MS, SPME-GC-MS stwierdzono występowanie fermonów należących do takich klas związków organicznych jak alkohole, węglowodory nasycone, aldehydy, kwasy karboksylowe i ketony.
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In vitro biodegradation of bacterial nanocellulose under conditions simulating human plasma in the presence of selected pathogenic microorganisms
PublikacjaThe Biodegradability of bacterial nanocellulose (BNC) was assessed based on a change in its properties under conditions simulating human plasma in the presence or absence of the pathogens Staphylococcus aureus, Candida albicans and Aspergillus fumigatus. It was shown that the dry mass of BNC did not change during 6 months of incubation, except for samples stored in the presence of moulds, where the dry mass reduced by 40 %. The...
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Classifying the transformation products (TPs) of emerging contaminants (ECs) for prioritizing research into their impact on the environment and human health
PublikacjaOne of the first books to cover transformation products, rather than primary compounds, Transformation Products of Emerging Contaminants in the Environment gathers, specifies, synthesizes, and advances existing knowledge of the most important transformation product (TPs) of the main groups of emerging contaminants with potential concern to human health and the environment. This two-volume set for researchers and professionals covers...
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Evaluation of a new freezing protocol containing 20% dimethyl sulphoxide concentration to cryopreserve human ovarian tissue
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A Simple Model of Linkage Disequilibrium and Genetic Drift in Human Genomic SNPs: Importance of Demography and SNP Age
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Surface sliding in human abdominal wall numerical models: Comparison of single-surface and multi-surface composites
PublikacjaDetermining mechanical properties of abdominal soft tissues requires a coupled experimental-numerical study, but first an appropriate numerical model needs to be built. Precise modeling of human abdominal wall mechanics is difficult because of its complicated multi-layer composition and large variation between specimens. There are several approaches concerning simplification of numerical models, but it is unclear how far one could...
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Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries
PublikacjaOne of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative...
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A Novel IoT-Perceptive Human Activity Recognition (HAR) Approach Using Multi-Head Convolutional Attention
PublikacjaTogether with fast advancement of the Internet of Things (IoT), smart healthcare applications and systems are equipped with increasingly more wearable sensors and mobile devices. These sensors are used not only to collect data, but also, and more importantly, to assist in daily activity tracking and analyzing of their users. Various human activity recognition (HAR) approaches are used to enhance such tracking. Most of the existing...
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Measurements and Visualization of Sound Intensity Around the Human Head in Free Field Using Acoustic Vector Sensor
PublikacjaThis paper presents measurements and visualization of sound intensity around the human head simulator in a free field. A Cartesian robot, applied for precise positioning of the acoustic vector sensor, was used to measure sound intensity. Measurements were performed in a free field using a head and torso simulator and the setup consisting of four different loudspeaker configurations. The acoustic vector sensor was positioned around...
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Characterization and cytotoxic effect of aqua-(2,2′,2′′-nitrilotriacetato)-oxo-vanadium salts on human osteosarcoma cells
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Selected extracts from Potentilla alba modulate the viability of normal and cancerous cells of the human colon epithelium
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Potentilla alba Extracts Affect the Viability and Proliferation of Non-Cancerous and Cancerous Colon Human Epithelial Cells
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Anticancer potential of acetone extracts from selected Potentilla species against human colorectal cancer cells
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In Vitro Anticancer Potential of Jasione montana and Its Main Components against Human Amelanotic Melanoma Cells
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Interactions of Nitroaromatic Compounds with the Mammalian Selenoprotein Thioredoxin Reductase and the Relation to Induction of Apoptosis in Human Cancer Cells
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Inhibition of phthalocyanine-sensitized photohemolysis of human erythrocytes by polyphenolic antioxidants: description of quantitative structure–activity relationships
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Erratum to: Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
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LY294002 and sorafenib as inhibitors of intracellular survival pathways in the elimination of human glioma cells by programmed cell death
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Badania poziomów zanieczyszczeń w płynach ustrojowych człowieka. Study of the level of pollution in human body fluids
PublikacjaŹródłem informacji o stanie środowiska mogą być zarówno wyniki badań próbek części nieożywionej (woda, gleba, powietrze) jak i próbki części biotycznej, w tym także tkanek i płynów ustrojowych człowieka, który jest nieustannie narażony na działanie szerokiego spektrum ksenobiotyków. W niniejszej pracy przedstawiono przegląd metod izolacji, wzbogacania i technik oznaczeń końcowych analitów z próbek moczu ludzkiego i krwi. Zawarto...
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Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells
PublikacjaW przedstawionych badaniach określano mechanizm śmierci komórkowej indukowanej przez imidazoakrydon C-1311 (Symadex) w komórkach HT-29 ludzkiego raka jelita grubego, które wykazywały szczególną wrażliwość na ten związek w eksperymentalnych modelach in vitro i in vivo. Przy stężeniu odpowiadającemu dawce IC99, związek powodował zahamowanie progresji cyklu komórkowej w fazie S po czym następował blok w fazie G2. Po czasach 48-96...
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A new methodological approach to the noise threat evaluation based on the selected physiological properties of the human hearing system
PublikacjaA new way of assessment of noise-induced harmful effects on human hearing system is presented in the paper. The method takes into consideration properties of the selected physiological human hearing system. On the basis of the hearing examinations and noise measurements results and psychoacoustical noise dosimeter performance the new indicators of the noise harmfulness were proposed. The evaluation of the proposed indicators were...
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A FEM membrane model of human fascia-synthetic implant system in a case of a stiff ventral hernia orifice
PublikacjaPraca prezdstawia model matematyczny układu tkanka ludzka - implant syntetyczny w postaci tzw. siatki w leczeniu przepuklin brzusznych. Implant jest tu moelowany jako struktura membranowa. Ocena wpływu danych materiałowych oraz wstępnego napięcia na zachowanie pracującej membrany po implantacji została przedstawiona na podstawie analizy wrażliwości. Pracę podsumowują pewne wskazówki dla chirurgów implantujących siatki.
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Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C
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Investigation of Iron and Zinc Concentrations in Human Milk in Correlation to Maternal Factors: An Observational Pilot Study in Poland
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Relation between polyphenols, malondialdehyde, antioxidant capacity, lactate dehydrogenase and toxic elements in human colostrum milk
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<p>Nanoparticles And Human Saliva: A Step Towards Drug Delivery Systems For Dental And Craniofacial Biomaterials</p>
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
PublikacjaA wide spectrum of brain rhythms are engaged throughout the human cortex in cognitive functions. How the rhythms of various low and high frequencies are spatiotemporally coordinated across the human brain during memory processing is inconclusive. They can either be coordinated together across a wide range of the frequency spectrum or induced in specific bands. We used a large dataset of human intracranial electroencephalography...
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
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Combined analysis of whole human blood parameters by Raman spectroscopy and spectral-domain low-coherence interferometry
PublikacjaIn this article the simultaneous investigation of blood parameters by complementary optical methods, Raman spectroscopy and spectral-domain low-coherence interferometry, is presented. Thus, the mutual relationship between chemical and physical properties may be investigated, because low-coherence interferometry measures optical properties of the investigated object, while Raman spectroscopy gives information about its molecular...
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New recombinant chimeric antigens, P35-MAG1, MIC1-ROP1, and MAG1-ROP1, for the serodiagnosis of human toxoplasmosis
PublikacjaThe aim of the study was to evaluate the usefulness of 3 chimeric Toxoplasma gondii antigens, P35-MAG1,MIC1-ROP1 andMAG1-ROP1, in the serodiagnosis of an acute toxoplasmosis in humans. Proteins were produced as fusion proteins containing His tags ends and then further purified by metal affinity chromatography. Their application for the diagnosis of recently acquired T. gondii infection was tested in IgG and IgM enzyme-linked immunosorbent...
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Cabbage Juices and Indoles Modulate the Expression Profile of AhR, ERα, and Nrf2 in Human Breast Cell Lines
PublikacjaOur previous studies showed the diversified effect of cabbage juices and indoles on the estrogen metabolism key enzymes (CYP1A1, CYP1A2, CYP1B1) in breast epithelial cells differing in ER status, i.e., in tumorigenic—MCF7, MDA-MB-231 and non-tumorigenic—MCF10A cells. The aim of the present study was to further investigate the mechanism of chemopreventive action of cabbage juice and its active components by evaluating their effect...
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Numerical model of human head phantom to ensure dosimetry of dose components for boron neutron capture therapy
PublikacjaExtremely important aspects of the boron neutron capture therapy are, first of all, administering to the patient a boron compound that selectively reaches the neoplastic cells, and in the second step, the verification of the irradiation process. This paper focuses on the latter aspect, which is the detailed dosimetry of the processes occurring after the reaction of thermal neutrons with the boron-10 isotope. The results of computer...
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Self-organising maps in the analysis of strains of human abdominal wall to identify areas of similar mechanical behaviour.
PublikacjaThe study refers to the application of a type of artificial neural network called the Self-Organising Map (SOM) for the identification of areas of the human abdominal wall that behave in a similar mechanical way. The research is based on data acquired during in vivo tests using the digital image correlation technique (DIC). The mechanical behaviour of the human abdominal wall is analysed during changing intra-abdominal pressure....