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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-MAG1L
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-LDH2
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-MIC3
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-ROP1
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-AMA1
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-GRA5
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen SAG1-SAG2-GRA2
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Analiza działania rozszerzonego obserwatora prędkości w szerokim zakresie zmian prędkości maszyny indukcyjnej
PublikacjaW artykule przedstawiono zagadnienia związane z odtwarzaniem zmiennych stanu maszyny indukcyjnej. Wykorzystano obserwator oparty na modelu matematycznym maszyny z dodatkowymi zmiennymi. Przedstawiono macierz stanu zlinearyzowanych równań błędu odtwarzania. Opisano sposób definiowania wyznacznika jakości na podstawie rozkładu biegunów obserwatora. Zaproponowano metodę korekcji wzmocnień wraz ze zmianą warunków pracy maszyny. Wykazano...
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Rapid multi-objective simulation-driven design of compact microwave circuits
PublikacjaA methodology for rapid multi-objective design of compact microwave circuits is proposed. Our approach exploits point-by-point Pareto set identification using surrogate-based optimization techniques, auxiliary equivalent circuit models, and space mapping as the major model correction method. The proposed technique is illustrated and validated through the design of a compact rat-race coupler. A set of ten designs being trade-offs...
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Music signal equalization in a changing environment
PublikacjaThe paper presents the concept of an automatic system for music signal correction, considering room frequency response and music genre being played. The proposed algorithm, based on the room frequency response, compensates acoustic conditions surrounding the sound source. Additionally, the compensation process considers the signal content by recognizing music genre. As part of the described research, a series of subjective tests...
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Robustness of contact-less optical method, used for measuring contact wire position in changeable lighting conditions
PublikacjaThe article presents verification of robustness of contactless method based on 2D image camera, which is used to measure catenary contact wire position in changeable ambient lighting conditions. Robustness in changeable lighting conditions is ensured through the combination of advanced image processing for background information removal and the algorithm of error correction. This algorithm detects incorrect images and substitutes...
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Dynamic variables limitation for backstepping control of induction machine and voltage source converter
PublikacjaDynamic variables limitation for backstepping control of induction machine and voltage source converter The paper presents the method of control of an induction squirrel-cage machine supplied by a voltage source converter. The presented idea is based on an innovative method of the voltage source converter control, consisting in direct joining of the motor control system with the voltage source rectifier control system. The combined...
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Application of auto calibration and linearization algorithms to improve sound quality of computer devices
PublikacjaAn application of auto calibration and linearization algorithms designed for correcting acoustic characteristics of selected computer devices was presented in the paper. The functionality of the algorithms were presented for two kind of computer devices: ultrabook class computer and portable device of All-In-One type. The algorithms were adjusted for the given type of the device on the basis of series of measurements conducted...
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Larmor diamagnetism and Van Vleck paramagnetism in relativistic quantumtheory: the Gordon decomposition approach
PublikacjaWe consider a charged Dirac particle bound in a scalar potential perturbed by a classical magnetic field derivable from a vector potential A(r). Using a procedure based on the Gordon decomposition of a field-induced current, we identify diamagnetic and paramagnetic contributions to the second-order perturbationtheory correction to the particle's energy. In contradiction to earlier findings, based on the sum-over-states approach,...
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Peculiarities of measurement uncertainty evaluation at calibrating a ring gauge
PublikacjaExample S13 from EA-4/02 M:2013 “Calibration of a ring gauge with a nominal diameter of 90 mm” is analyzed. The report uses the kurtosis method and the law of propagation of expanded uncertainty developed by the authors to the expanded uncertainty evaluation. It is shown that the introduction of a coaxiality correction for the ring gauge and the measuring axis of the comparator leads to the need to estimate its standard measurement...
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Metaheurystyki sztucznej inteligencji w wybranych grach komputerowych
PublikacjaW pracy omówiono trzy metaheurystyki sztucznej inteligencji, które mogą stać się źródłem inspiracji dla projektantów gier komputerowych. Pokazano, w jaki sposób zastosowano algorytm mrówkowy, algorytm genetyczny i algorytm tabu search w grach komputerowych zaprojektowanych przez studentów Politechniki Gdańskiej. W szczególności, odniesiono się do problematyki wyznaczania trajektorii przemieszczających się obiektów...
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A multi‑criteria approach to investigate spatial distribution,sources, and the potential toxicological effect of polycyclic aromatic hydrocarbons (PAHs) in sediments of urban retention tanks
PublikacjaBottom sediments deposited in retention tanks (RTs) located on two urban streams (Oliwski and Strzyza) in the central part of Gdansk (Poland) were analysed for polycyclic aromatic hydrocarbons’ (PAHs) content. PAHs were extracted from samples with methylene chloride, then the extracts were subjected to clean-up applying the solid phase extraction (SPE) method. Quantitative and qualitative determination of 16 PAHs was performed...
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Możliwości i korzyści z likwidacji zużytych modułów PV
PublikacjaSystemy fotowoltaiczne stanowią proekologiczną alternatywę dla konwencjonalnych źródeł zasilania. Jednak aby pozostawały one bez negatywnego wpływu na środowisko, konieczne jest rozwiązanie problemu zagospodarowania zużytych elementów tych systemów. Do tej pory ani przemysł, ani ustawodawstwo nie wypracowały uniwersalnej metody likwidacji modułów, wycofanych z użytku - tych, które uległy uszkodzeniu oraz tych, dla których skończył...
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Radzenie sobie ze stresem w warunkach różnego stopnia zagrożenia zdrowia.
PublikacjaCelem pracy była ocena zróżnicowania podejmowanych strategii zaradczych oraz siły poczucia koherencji u kobiet w różnym stanie zdrowia. W badaniu uczestniczyły kobiety zdrowe (n=79), zagrożone chorobą nowotworową (n=41) oraz chore na nowotwór narządów rodnych (n=118). Stwierdzono, że w stanach deficytu zdrowia preferowane są strategie emocjonalne, a w zdrowiu - instrumentalne. Dominującą strategią w radzeniu sobie z chorobą nowotworową...
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Preparation and evaluation of 1,3-alternate 25,27-bis-(pentafluorobenzyloxy)-26,28-bis-(3-propyloxy)-calix[4]arene-bonded silics gel high performance liquid chromatography stationary phase
PublikacjaA 1,3-alternate 25,27-bis-(pentafluorobenzyloxy)-26,28-bis-(3-propyloxy)-calix[4]arene-bonded silica gel stationary phase (CalixBzF10) was synthesized, structurally characterized, and used as a selector in liquid chromatography. The selectivity study of this phase was done by using fluorine-containing compounds (fluorobenzenes, fluoro-pyrimidine bases), as well as non-fluorinated analytes (non-steroidal anti-inflammatory drugs,...
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RESEARCH ON ORGANIC COATINGS DESIGNED FOR UNDERWATER APPLICATIONS
PublikacjaUnderwater steel structures require periodic maintenance. In the case of vessels, anti-corrosion works are carried out in the shipyard, where very good conditions for applying organic protective coatings can be provided. Very good surface preparation can be obtained by the use of abrasive blasting. The well-prepared metal surface is free from impurities (particularly inorganic salts). Suitable conditions for the application and...
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Interfacial water controls the process of adsorption of hyperactive antifreeze proteins onto the ice surface
PublikacjaA mechanism of interactions between the ice-binding surface of a hyperactive antifreeze protein molecule and the ice surface is proposed, involving the influence of water present between the two surfaces on the behavior of the approaching molecule. It is demonstrated that the interfacial water, even before its full solidification, can act as a factor that pushes away or pulls nearer the protein molecule to ensure its proper positioning....
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FROM HARVESTING TO DISTILLATION - EFFECT OF ANALYTICAL PROCEDURES ON THE YIELD AND CHEMICAL COMPOSITION OF RHODODENDRON TOMENTOSUM (LEDUM PALUSTRE) ESSENTIAL OIL
PublikacjaRhododendron tomentosum possesses the anti-inflammatory, analgesic and antimicrobial properties, determined by the chemical composition of its essential oil. The effects of place (Miszewko, Lubichowo) and time of harvesting (June, November) as well as drying (air-drying, oven-drying, freeze-drying) and isolation (in Deryng, Clevenger and Likens-Nickerson apparatus) procedures on the yield and quality of R. tomentosum essential...
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Induction of immune responses in sheep by vaccination with liposome-entrapped DNA complexes encoding Toxoplasma gondii MIC3 gene
PublikacjaToxoplasma gondii is a parasite that has been extensively studied due to its medical and veterinary importance in terminating pregnancies. Consequently, a satisfactory vaccine is required to control itsadverse effects on pregnant animals. The microneme protein, MIC3, is a major adhesion protein that binds to the surface of host cells and parasites, and is therefore a potential vaccine against T. gondii.The viability of MIC3 as...
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Low-Barrier Hydrogen Bond Determines Target-Binding Affinity and Specificity of the Antitubercular Drug Bedaquiline
PublikacjaThe role of short strong hydrogen bonds (SSHB) in ligand-target binding remains largely unexplored, thereby hin- dering a potentially important avenue in the rational drug de- sign. Here, we investigate the interaction between bedaquiline (Bq), a potent anti-tuberculosis drug, and the mycobacterial ATP synthase, to unravel the role of a specific hydrogen bond to a conserved acidic residue in the target affinity and specificity....
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Photofragmentation of tetrahydrofuran molecules in the vacuum-ultraviolet region via superexcited states studied by fluorescence spectroscopy
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Magnetotransport properties of the correlated topological nodal-line semimetal YbCdGe
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Other diseases of pericardium - Male, 0 - Tissue image [4050730010687431]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other diseases of pericardium - Male, 0 - Tissue image [4050730010688491]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other diseases of pericardium - Male, 0 - Tissue image [4050730010687711]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other diseases of pericardium - Male, 0 - Tissue image [4050730010686101]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other diseases of pericardium - Male, 0 - Tissue image [405073001068941]
Dane BadawczeThis is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Evaluation of immune responses in sheep induced by DNA immunization with genes encoding GRA1, GRA4, GRA6 and GRA7 antigens of Toxoplasma gondii
PublikacjaW niniejszej pracy oszacowano odpowiedź immunologiczną owiec szczepionych domięśniowo szczepionkami DNA zawierającymi geny kodujące cztery antygeny granul o dużej gęstości (GAR1, GRA4, GRA6 oraz GRA7) Toxoplasma gondii. Wykazano, iż wykorzystanie DNA plazmidu pGRA7 indukuje znaczący poziom przeciwciał IgG-2 anty-GRA7 oraz IFN-gammma, podczas gdy iniekcja pGRA1, pGRA4 oraz pGRA6 stymuluje odpowiedź przeciwciał IgG1 z ograniczoną...
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Sektorowe zróżnicowanie płynności finansowej przed-siębiorstw
PublikacjaPłynność finansowa warunkuje prawidłowość funkcjonowania całej firmy. Uzależniona jest od niej możliwość przetrwania przedsiębiorstwa na rynku oraz perspektywa jego rozwoju. Artykuł podejmuje tematykę zróżnicowania płynności finansowej przedsiębiorstw w zależności od ich przynależności sek-torowej. Z przeprowadzonych badań wynika, że wartość wskaźników z obsza-ru płynności finansowej jest silnie zróżnicowana w przekroju sektorowym....
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Equivalent Single Layer Models in Free Vibration Analysis of Laminated Multi-Layered Plates
PublikacjaThe performance of selected equivalent single-layer (ESL) models is evaluated within several classical benchmark tests for small amplitude free vibration analysis of multi-layered plates. The authors elaborated their own Finite Element software based on the first-order shear deformation (FOSD) theory with some modifications incorporated including a correction of the transverse shear stiffness and an application of zigzag type functions....
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Rapid dimension scaling of triple-band antennas by means of inverse surrogate modeling
PublikacjaGeometry scaling of antennas, i.e., finding optimum dimensions of the structure for given operating conditions and material parameters is an important yet challenging problem. In this paper, we discuss fast dimension scaling of triple-band antennas with respect to operating frequencies. We adopt the inverse surrogate modeling approach where the surrogate model is a function of the three operating frequencies of the antenna and...
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Analysis of Vibration and Acoustic Signals for Noncontact Measurement of Engine Rotation Speed
PublikacjaThe non-contact measurement of engine speed can be realized by analyzing engine vibration frequency. However, the vibration signal is distorted by harmonics and noise in the measurement. This paper presents a novel method for the measurement of engine rotation speed by using the cross-correlation of vibration and acoustic signals. This method can enhance the same frequency components in engine vibration and acoustic signal. After...
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Potential energy curves and spectroscopic parameters of the diatomic silver anion and neutral silver dimer
Dane BadawczeThe process of a two-channel decay of the diatomic silver anion (Ag2-), namely the spontaneous electron ejection giving Ag2 + e- and the dissociation leading to Ag- + Ag is theoretically studied. The ground state potential energy curves (PECs) of the neutral silver dimer and anionic silver diatomic molecule are calculated using the single reference...
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Design principles for creating digital transparency in government
PublikacjaUnder pressure to fight corruption, hold public officials accountable, and build trust with citizens, many governments pursue the quest for greater transparency. They publish data about their internal operations, externalize decision-making processes, establish digital inquiry lines to public officials, and employ other forms of transparency using digital means. Despite the presence of many transparency-enhancing digital tools,...
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Węzły grupy A
PublikacjaWęzły grupy A są budowane na przecięciach tych dróg szybkiego ruchu, z których definicji wynika, że nie mogą one krzyżować się w jednym poziomie ani z inną drogą szybkiego ruchu lub ogólnodostępną, ani z drogą łącznikową. Sprawność sieci drogowej zależy w głównej mierze od sprawności węzłów, czyli ich przystosowania do wymagań ruchu o dużych natężeniach, często zmieniających się w czasie. W opracowaniu opisano następujące rodzaje...
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Porównanie atrakcyjności zajęć chemicznych z wykorzystaniem doświadczeń chemicznych, eksperymentów w rzeczywistości rozszerzonej oraz multimediów dla uczniów gimnazjów
PublikacjaPrzeprowadzone badania wykazały, że istnieją statystycznie istotne różnice w ocenie atrakcyjności poszczególnych narzędzi. Możliwość eks- perymentowania (samodzielnego oraz przy zastosowaniu środowiska AR) przekładała się na odbiór takiej metody jako bardziej atrakcyjnej – w po- równaniu z zastosowaniem multimediów. I jak wskazują zebrane dane nie ma na to wpływu ani płeć, ani obszar pochodzenia ucznia. Proponowane badania pozwoliły...
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Niechciany ''Pomost'' jako świadek destrukcji tkanki architektonicznej w Parku Nadmorskim w Sopocie = The unwanted ''Walking Overpass'' as the Witness to the destruction pf architectural tissue in the Seaside Park in Sopot
PublikacjaW referacie zawarta jest refleksja nad bezkarnym działaniem niszczycielskim w najdelikatniejszej strukturze krajobrazu miasta nadmorskiego. Krajobrazu ani jego dobrej pierwotnej tkanki nie da się odtworzyć tak szybko jak się ją niszczyło. W efekcie zapomnieliśmy, że piękno spaceru w Parku Nadmorskim jest wspólnym dobrem.
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Możliwości redukcji przebiegowego zużycia paliwa przy zastosowaniu elektronicznych systemów wspomagających kierowców
PublikacjaElektroniczne systemy wspomagające kierowcę pomagają kierującym kontrolować sytuację na drodze, przekazują sygnały do układu hamulcowego i napędowego, rozpoznają znaki drogowe, pozwalają utrzymać odpowiedni dystans w czasie jazdy w kolumnie, a także kontrolują położenie pojazdu na pasie ruchu. Elek-troniczne systemy wspomagające kierowcę pomagają również zmniejszyć przebiegowe zużycie paliwa, poprzez odpowiednie sterowanie układem...
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Biomolecular influenza virus detection based on the electrochemical impedance spectroscopy using the nanocrystalline boron-doped diamond electrodes with covalently bound antibodies
PublikacjaNew rapid pathogen detection methods with improved cost-effectiveness and efficiency are currently in the focus of the scientists from all over the world. Based on the experiences from the rapid spread of the influenza virus pandemic in 2009 it is clear that the development of the system for early diagnosis of this infection is essential. The crucial stage of the treatment is the detection of the viral infection during its initial...
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Inhibition of T-type calcium channel disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
PublikacjaGlioblastoma multiforme (GBM) are brain tumors that are exceptionally resitant to both radio- and chemotherapy regimens and novel approaches to treatment are needed. T-type calcium channels are one type of low voltage-gated channel (LVCC) involved in embryonic cell proliferation and differentiation; however they are often over-expressed in tumors, including GBM. In this study, we found that inhibition of T-type Ca channels in GBM...
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Phytochemical composition and biological activities of differently pigmented cabbage (Brassica oleracea var. capitata) and cauliflower (Brassica oleracea var. botrytis) varieties
PublikacjaBACKGROUND:Brassica plants contain awide spectrumofbioactive components that are responsible for their health-promoting potential such as vitamins, polyphenols and glucosinolates. This study attempted to relate the composition of bioactive phytochemicals and chosen biological activities (antioxidant, cytotoxic, anti-genotoxic, and influence on enzymatic activities) for extracts from differently pigmented cabbage (white and red)...
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Phylogenetic analysis of Oncidieae subtribe - ITS1-5,8S-ITS2
Dane BadawczeThe dataset contains alignment and consensus matrix files, and results of phylogenetic analysis of ITS1- 5,8S-ITS2 region from 186 orchid species considered to belong Oncidieae subtribe. Sequences were assessed from NCBI GeneBank (list of all records with identifiers in the separate file)
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Phylogenetic analysis of Oncidieae subtribe - matK plastid region
Dane BadawczeThe dataset contains alignment and consensus matrix files, and results of phylogenetic analysis of plastid matK region from 186 orchid species considered to belong Oncidieae subtribe. Sequences were assessed from NCBI GeneBank (list of all records with identifiers in the separate file)
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AUDIO SIGNAL EQUALIZATION BASED ON IMPULSE RESPONSE OF A LISTENING ROOM AND MUSIC CONTENT REPRODUCED
PublikacjaA research study presents investigations of the influence of the room acoustics on the frequency characteristic of the audio signal playback. First, a concept of a novel spectral equalization method of the room acoustic conditions is introduced. On the basis of the room spectral response, a system for room acoustics compensation based on an equalizer designed is proposed. The system settings depend on music genre recognized automatically....
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Fixed Pattern Noise Reduction and Linearity Improvement in Time-Mode CMOS Image Sensors
PublikacjaIn the paper, a digital clock stopping technique for gain and offset correction in time-mode analog-to-digital converters (ADCs) has been proposed. The technique is dedicated to imagers with massively parallel image acquisition working in the time mode where compensation of dark signal non-uniformity (DSNU) as well as photo-response non-uniformity (PRNU) is critical. Fixed pattern noise (FPN) reduction has been experimentally validated...