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Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer
PublikacjaThe molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed the expression of the TERT, MYC, TP53 and SP1 genes in BC patients and in BC organoids (3D cell cultures obtained from breast cancer tissues). We observed the same correlation in the...
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The importance of trust and altruistic social orientation for COVID-19 distress
PublikacjaBackground: The COVID-19 pandemic, the biggest global health crisis in decades, has been a difficult experience for nations all over the world. In the present study we wanted to assess to what extent a positive attitude towards others, expressed in altruistic social orientation and a high level of trust, would be linked to lower levels of COVID-19 distress in infected and non-infected individuals. Participants and procedure:...
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Recent Advances in Loop Heat Pipes with Flat Evaporator
PublikacjaThe focus of this review is to present the current advances in Loop Heat Pipes (LHP) with flat evaporators, which address the current challenges to the wide implementation of the technology. A recent advance in LHP is the design of flat-shaped evaporators, which is better suited to the geometry of discretely mounted electronics components (microprocessors) and therefore negate the need for an additional transfer surface (saddle)...
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Numerical simulation of temperature distribution of heat flow on reservoir tanks connected in a series
PublikacjaThe flow of temperature distribution through a medium in thermodynamic studies plays an important role in understanding physical phenomena in chemical science and petroleum engineering, while temperature distribution indicates the degree of reaction that must be undergone to obtain the final product. Therefore, this paper aims to present and apply the exponential matrix algorithm (EMA), differential transformation algorithm (DTA),...
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Adam Władziński
OsobyAdam Władziński, doktorant na Politechnice Gdańskiej, specjalizuje się w inżynierii biomedycznej, skupiając się na uczeniu maszynowym do przetwarzania obrazów z druku 3D układów pomiarowych i tkanek biologicznych, a także na komercyjnym zastosowaniu technologii blockchain. Posiadając wykształcenie z dziedziny elektroniki na Wydziale Elektroniki, Telekomunikacji i Informatyki (ETI), praca magisterska Adama Władzińskiego koncentrowała...
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Comparing Apples and Oranges: A Mobile User Experience Study of iOS and Android Consumer Devices
PublikacjaWith the rapid development of wireless networks and the spread of broadband access around the world, the number of active mobile user devices continues to grow. Each year more and more terminals are released on the market, with the smartphone being the most popular among them. They include low-end, mid-range, and of course high-end devices, with top hardware specifications. They do vary in build quality, utilized type of material,...
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Baltic Phytoremediation - Training Module
Kursy OnlineThis is an on-line training course developed in BAPR - Baltic Phytoremediation project, co-financed by Interreg South Baltic Programme 2014 - 2020. Here, You can learn about the basics and potential of phytoremediation to clean soil and see the real-life applications of this technology. In order to be enrolled to this course, you’ll need to create a local account with the user ID provided. When your account is generated, you...
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Identification of Parameters Influencing the Accuracy of the Solution of the Nonlinear Muskingum Equation
PublikacjaTwo nonlinear versions of the Muskingum equation are considered. The difference between both equations relates to the exponent parameter. In the first version, commonly used in hydrology, this parameter is considered as free, while in the second version, it takes a value resulting from the kinematic wave theory. Consequently, the first version of the equation is dimensionally inconsistent, whereas the proposed second one is consistent. It...
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The condition of economies. Do most valuable global brands matter?
PublikacjaResearch background: Brands are considered to be the most valuable asset of a company. Some of them achieve spectacular global results. The significance of global brands is proved by the fact that their value is often greater than the sum of all company’s net assets. Purpose of the article: The aim of this article is to highlight that brand value does not only create company’s value, but also leverages economies. The Authors claim...
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Providing Public Space Continuities in Post-Industrial Areas through Remodelling Land/Water Connections
PublikacjaThis article examines the problem of urban transformation strategies applied in recent years which are based on the creation of new water areas and modification of existing ones. The research is an attempt to prove that modifications of plans of water areas and forms of their borders may play an important role in achieving the best quality public spaces in post-industrial territories. The basis for demonstrating the importance...
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Improving the CPX method by specifying reference tyres and including corrections for rubber hardnes and temperature
PublikacjaRecently completed work in the EU project ROSANNE and in working group ISO/TC43/SC1/WG33 has allowed substantial improvements to measurements made by the Close-Proximity (CPX) method, intended for measurement of noise properties of road surfaces.The paper summarizes the experimental work and describes the conclusions and implementation in ISO/FDIS 11819-2 (CPX method) and in the supporting ISO (draft) Technical Specifications 11819-3...
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Blockchain based Secure Data Exchange between Cloud Networks and Smart Hand-held Devices for use in Smart Cities
PublikacjaIn relation to smart city planning and management, processing huge amounts of generated data and execution of non-lightweight cryptographic algorithms on resource constraint devices at disposal, is the primary focus of researchers today. To enable secure exchange of data between cloud networks and mobile devices, in particular smart hand held devices, this paper presents Blockchain based approach that disperses a public/free key...
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Combinated treatment of landfill leachates with wastewater in a sequencing batch reactor (SBR)
PublikacjaSanitary landfill leachates are treated usually by multistage systems using physical, chemical and biological processes. One of the most economic and efficient method is combined treatment of landfill leachates with municipal wastewater in a sequencing batch reactor (SBR. The main advantage of such co-treatment is that landfill leachates variability (in quality and quantity) do not influence the effectiveness of biological processes....
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Nonlinear Control of a Doubly Fed Generator Supplied by a Current Source Inverter
PublikacjaNowadays, wind turbines based on a doubly fed induction generator (DFIG) are a commonly used solution in the wind industry. The standard converter topology used in these systems is the voltage source inverter (VSI). The use of reverse-blocking insulated gate bipolar transistor (RB-IGBT) in the current source inverter topology (CSI), which is an alternative topology, opens new possibilities of control methods. This paper presents...
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Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
PublikacjaProliferation and expansion of leukemia is driven by leukemic stem cells (LSCs). Multidrug resistance (MDR) of LSCs is one of the main reasons of failure and relapses in acute myeloid leukemia (AML) treatment. In this study, we show that maintaining HL-60 at low cell culture density or applying a 240-day treatment with anthrapyridazone (BS-121) increased the percentage of primitive cells, which include LSCs determining the overall...
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Photoresponsive Amide-Based Derivatives of Azobenzene-4,4′-Dicarboxylic Acid—Experimental and Theoretical Studies
PublikacjaAzobenzene derivatives are one of the most important molecular switches for biological and material science applications. Although these systems represent a well-known group of compounds, there remains a need to identify the factors influencing their photochemical properties in order to design azobenzene-based technologies in a rational way. In this contribution, we describe the synthesis and characterization of two novel amides...
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Neurochemical changes underlying cognitive impairment in olfactory bulbectomized rats and the impact of the mGlu5-positive allosteric modulator CDPPB
PublikacjaThe olfactory bulbectomized (OBX) rat model is a well-established model of depression in which antidepressant drugs reverse deficits in the passive avoidance test 14 days after administration. Recently, the olfactory bulbectomized rat model has been proposed to be a model of Alzheimer’s disease (AD), and the available data indicate similarities between the changes that typically occur in AD and those observed in OBX animals. In...
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Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism
PublikacjaIn spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one of the greatest challenges in long-term management of CRC and urges need for new leads of anticancer drugs. We demonstrate that CRC...
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Nanoparticles and nanofiltration for wastewater treatment: From polluted to fresh water
PublikacjaWater pollution poses significant threats to both ecosystems and human health. Mitigating this issue requires effective treatment of domestic wastewater to convert waste into bio-fertilizers and gas. Neglecting liquid waste treatment carries severe consequences for health and the environment. This review focuses on intelligent technologies for water and wastewater treatment, targeting waterborne diseases. It covers pollution prevention...
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Labour share and income inequalities in the European Union, taking into account the level of development of economies
Publikacjaesearch background: The relationship between labour share and income inequality is a complex and multifaceted problem. Despite ongoing discussions among economists, there is still no consensus on the direction of the relationship between labour share and income ine-quality. Purpose of the article: The article aims to assess the impact of labour share on income inequal-ity, which is measured in three ways: the Gini index...
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The role of glucuronidation in drug resistance
PublikacjaThe final therapeutic effect of a drug candidate, which is directed to a specific molecular target strongly depends on its absorption, distribution, metabolism and excretion (ADME). The disruption of at least one element of ADME may result in serious drug resistance. In this work we described the role of one element of this resistance: phase II metabolism with UDP-glucuronosyltransferases (UGTs). UGT function is the transformation...
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Briding the communicational gap between client and software developer
PublikacjaOften is it the case that people find it difficult to bridge thecommunicational gap between themselves and others. This is something of a problem, to say the least. My aim is to explain and to clarify the reasons behind this and to hopefully overcome any obstacles, to allow for a much smoother and more accurate means of fulfilling client and software developer needs.I have found through my own personal experience something which...
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Professional activity and women entrepreneurship in Poland – Europe 2020 Strategy perspective
PublikacjaThe level of economic activity of women in Poland is the lowest among Baltic Sea Region countries. The analysis of Europe 2020 targets, shows that at least 3 of the 5 main objectives relate, more or less, to women (e.g. participation in labor market). The objective concerning social inclusion assumes the increase in the employment rate of men and women (aged 20-64) in Poland up to 71%. To achieve this goal, support programs to...
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Rhythm and Colours of the Angles
PublikacjaABSTRACT The game of space was and still is a crucial aspect of visual arts. The aim of this study is to examine how the arrangement of hues, rhythms and angles of various polygons can create an impression of depth and movement on a flat surface. The so-called Penrose tiling and Ulam's spiral are mathematical models that have been applied for the painting experiment. There is a vast amount of evidence gathered over the ages that...
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LABORATORIUM SZYBKIEGO PROTOTYPOWANIA : Inżynieria odwrotna
PublikacjaSzybkie prototypowanie (ang. Rapid Prototyping) i inżynieria odwrotna (ang. Reverse Engineering) są jednymi z najbardziej dynamicznie rozwijających się działów komputerowego wspomagania projektowania, wytwarzania i realizacji prac inżynierskich (CAD/CAM/CAE). Inżynieria odwrotna stanowi zwykle wyjściowy etap szybkiego prototypowania. Udostępnia ona metody generowania wirtualnych modeli 3D istniejących obiektów w wyniku ich pomiarów....
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"How to Write a Scientific Manuscript"
Kursy Online{mlang pl} Zajęcia nieobowiązkowe, poza programem kształcenia. Prowadzący: Dr. Mohammad Reza Saeb W przypadku pytań, prosimy o kontakt z Samorządem Doktorantów, który jest organizotrem kusru (najlepiej bezpośrednio z p. Adamem Olszewskim). {mlang} {mlang en} Optional courses, not included in the training programme. Academic teacher: Dr. Mohammad Reza Saeb If you have any questions, please contact the PhD Student Union, which...
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City scan as a tool to assess resilience challenges and vulnerabilities at the community level
PublikacjaThe majority of the world’s population lives in cities and cities are the key to achieving resilience. Local governments own only part of the land and can only partially decide about measures that should be taken ‘on the ground’. Local governments are therefore highly dependent on individuals, communities, and businesses to adapt and transform and take action in their own backyards or neighbourhoods. Since, for many people, climate...
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Analysis of Transformation Methods of Hydroacoustic and Optoelectronic Data Based on the Tombolo Measurement Campaign in Sopot
PublikacjaMeasurements in the coastal zone are carried out using various methods, including Global Navigation Satellite Systems (GNSS), hydroacoustic and optoelectronic methods. Therefore, it is necessary to develop coordinate transformation models that will enable the conversion of data from the land and marine parts to one coordinate system. The article presents selected issues related to the integration of geodetic and hydrographic data....
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Geochemical fractionation of organic matter in the Jurassic-Cretaceous Vaca Muerta shale, Argentina
PublikacjaSeveral studies have indicated the presence of more than one generation of bitumen that could be isolated from rocks through sequential extraction or after demineralization or both. Nabbefeld et al. (2010a) and Holman et al. (2012, 2014) termed bitumen obtained after solvent extraction from the undigested rock as “Bitumen I" and that obtained by extraction after demineralization of rock as “Bitumen II.” The occurrence of different...
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Migration of container terminals as their natural process of evolution: Case study of Gdańsk and Gdynia ports
PublikacjaThe paper proposes a theoretical model of container terminals and container port development, based on the life cycle theory, threshold theory and catastrophe theory, and in references to Kuznets' swings (interpreted as waves of infrastructural investments), and Kondratiev long economic waves. The aim of this model is to explain the development process of a container terminal and a port within one technological generation, as...
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Advanced nanomaterials and metal-organic frameworks for catalytic bio-diesel production from microalgal lipids – A review
PublikacjaIncreasing energy demands require exploring renewable, eco-friendly (green), and cost-effective energy resources. Among various sources of biodiesel, microalgal lipids are an excellent resource, owing to their high abundance in microalgal biomass. Transesterification catalyzed by advanced materials, especially nanomaterials and metal-organic frameworks (MOFs), is a revolutionary process for overcoming the energy crisis. This review...
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Using Decisional DNA to Enhance Industrial and Manufacturing Design: Conceptual Approach
PublikacjaDuring recent years, manufacturing organizations are facing market changes such as the need for short product life cycles, technological advancement, intense pressure from competitors and the continuous customers’ expectation for high quality products at lower costs. In this scenario, knowledge and its associated engineering/management of every stage involved in the industrial design has become increasingly important for manufacturing...
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Distribution and bioavailability of mercury in the surface sediments of the Baltic Sea
PublikacjaThe study aimed to determine the level of mercury (Hg) and its labile and stable forms in the surface sediments of the Baltic Sea. The work considers the impact of current and historical sources of Hg on sediment pollution, together with the influence of different environmental parameters, including water inflows from the North Sea. Surface sediments (top 5 cm) were collected in 2016–2017 at 91 stations located in different...
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Enhancing chain-elongating microbiomes: Sequential fungi-bacteria cooperation for efficient food waste upgrading using endogenous electron donors
PublikacjaThe upgrading of organic waste such as food waste (FW) into medium-chain carboxylates (MCC) is within a bio-based circular economy concept. An efficient chain elongation (CE) microbiome is difficult to obtain, which normally requires long-term acclimatization and an exogenous supplement of electron donor (ED, especially ethanol). In this study, the CE microbiome was rapidly shaped within 18 days and an efficient endogenous ethanol-based...
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The Relation Between Art and Physical Activity in the Public Space of the Contemporary City
PublikacjaArt has always been and still is a mirror in which human activity is reflected. One of the basic human activities is physical activity, thanks to which humans are able to satisfy their needs, improve health and also function in society. Therefore, there are different relationships between physical activity and art. Both of them are present in the public space of cities and this aspect of connection is addressed in the article. The...
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Baltic Smart Asset Management - Training Module
Kursy OnlineBaltic Smart Asset Management is an international project co-financed by the funds from Interreg South Baltic Programme 2014-2020. The aim of the project is to develop methods, transnational collaboration processes and knowledge about Smart Asset Management (SAM) for District Heating (DH) sector. The training module will help to spread the professional knowledge on new solutions and applications of SAM methods to promote data-driven...
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A vector-enzymatic DNA fragment amplification-expression technology for construction of artificial, concatemeric DNA, RNA and proteins for novel biomaterials, biomedical and industrial applications
PublikacjaA DNA fragment amplification/expression technology for the production of new generation biomaterials for scientific, industrial and biomedical applications is described. The technology enables the formation of artificial Open Reading Frames (ORFs) encoding concatemeric RNAs and proteins. It recruits the Type IIS SapI restriction endonuclease (REase) for an assembling of DNA fragments in an ordered head-to-tail-orientation. The...
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Functioning and legal regulations of perpetual usufruct right in Poland in relation to similar rights in other countries of the European Union
Publikacja1 May 2004, Poland became part of the European Union, which main aim is the political, economic and social integration of democratic European countries as well as the construction of a common market ensuring of persons, goods, services and capital move freely. The Accession Treaty provides some transitional periods for the adjustment of the right of Member States to the EU regulations. Next year, 12 years after joining the EU,...
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Integrating Digital Twin Technology Into Large Panel System Estates Retrofit Projects
PublikacjaAs sustainability is now a standard for the proposed developments, the focus ought to be shifted towards the existing buildings and, among them, the worldwide stock of large panel system (LPS) buildings. Major upgrades and retrofits were done to some of the LPS estates in Germany and France, but a leading sustainable way must still be developed for LPS buildings in Eastern European countries, where apartments in those half‐a‐century‐old...
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Investigation on air quality of specific indoor environments—spa salons located in Gdynia, Poland
PublikacjaDue to excessive application of essential oils and scented products in spa salons during aromatherapy and massage sessions, the elevated concentration of total volatile organic compounds (TVOCs), particularly terpenes, which are known as secondary organic aerosol (SOA) precursors, is expected there. This study was aimed at determination of VOCs with a particular regard to terpenes in air samples collected in selected spa salons...
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Types of Markov Fields and Tilings
PublikacjaThe method of types is one of the most popular techniques in information theory and combinatorics. However, thus far the method has been mostly applied to one-dimensional Markov processes, and it has not been thoroughly studied for general Markov fields. Markov fields over a finite alphabet of size m ≥ 2 can be viewed as models for multi-dimensional systems with local interactions. The locality of these interactions is represented...
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THRIVING AND JOB SATISFACTION IN MULTICULTURAL ENVIRONMENTS OF MNCS
PublikacjaPurpose of the article The aim of the paper is to analyze the relationship between thriving and job satisfaction in multicultural environments of multinational corporations (MNCs). Methodology/methods The quantitative cross-sectional study was conducted on the sample of 128 individuals from subsidiaries of various MNCs located in Poland involved in intercultural interactions. Scientific aim The aim of this study was to examine...
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SDGs implementation, their synergies, and trade-offs in EU countries – Sensitivity analysis-based approach
PublikacjaSustainable development is one of the most urgent challenges facing humanity. Its basic principle is to improve people’s well-being and maintain it over time. In 2015, the United Nations approved 17 sustainable development goals (SDGs) to ensure a better and sustainable future for all, balancing economic, social and environmental development. SDGs create an ‘indivisible whole’; thus, examining their interactions is crucial. Our...
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Application of Mathematics in Technology, ET, sem 3, 23/24, (PG_00049767)
Kursy OnlineApplication of Mathematics MOODLE ENV localdevtestprod
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Application of Mathematics in Technology for Dezhou University, 2023
Kursy OnlineApplication of Mathematics MOODLE ENV localdevtestprod
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Modelling Signalised Intersections Reliability of Functioning
PublikacjaThe article addresses a fundamental aspect of traffic, i.e. the operation of traffic signals at intersections, in reference to the reliability theory. In many cases, when intersections carry substantial amounts of traffic, selecting control parameters to produce satisfactory traffic conditions is quite difficult. Design methods do not cover all possible situations which are the result of intersection geometry and location...
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Membrane Sterols Modulate the Binding Mode of Amphotericin B without Affecting Its Affinity for a Lipid Bilayer
PublikacjaMembrane-active antibiotics are known to selectively target certain pathogens based on cell membrane properties, such as fluidity, lipid ordering, and phase behavior. These are in turn modulated by the composition of a lipid bilayer and in particular by the presence and type of membrane sterols. Amphotericin B (AmB), the golden standard of antifungal treatment, exhibits higher activity toward ergosterol-rich fungal membranes, which...
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Improved finite element method for flow, heat and solute transport of Prandtl liquid via heated plate
PublikacjaIn the current study, a vertical, 3D-heated plate is used to replicate the generation of heat energy and concentration into Prandtl liquid. We discuss how Dufour and Soret theories relate to the equations for concentration and energy. In order to see how efectively particles, interact with heat and a solvent, hybrid nanoparticles are used. It does away with the phenomena of viscous dissipation and changing magnetic felds. The motivation...
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Novel DNA-binding protein from Nanoarchaeum equitans Kin4-M binds all kinds of nucleic acids
PublikacjaNanoarchaeum equitans is the only known representative of Archaea phylum Nanoarchaeota and stands out as one of the tiniest known living organism. What is more it has smallest genome, which is only 490.885 base pairs long. It is also one of the most compact genomes. According to predictions about 95% of the DNA encodes proteins or stable RNA. Nanoarchaeum equitans lacks genes for most vital metabolic pathways including lipid, cofactor,...
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Nanoparticles preparation using microemulsion systems
PublikacjaMetallic nanoparticles become of current interests because they exhibit unique properties compared with those of metal atoms or bulk metal due to the quantum size effect and their large surface area, which make them attractive for applications in optics, electronics, catalysis biology and medicine. TiO2 has been used for environmental remediation purposes such as in the purification of water and air and also solar-to chemical energy...