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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
PublicationThe genome feature of SARS-CoV-2 leads the virus to mutate and creates new variants of concern. Tackling viral mutations is also an important challenge for the development of a new vaccine. Accordingly, in the present study, we undertook to identify B- and T-cell epitopes with immunogenic potential for eliciting responses to SARS-CoV-2, using computational approaches and its tailoring to coronavirus variants. A total of 47 novel...
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Sensitive Demonstration of the Twin-Core Couplers including Kerr Law Non-Linearity via Beta Derivative Evolution
PublicationTo obtain new solitary wave solutions for non-linear directional couplers using optical meta-materials, a new extended direct algebraic technique (EDAT) is used. This model investigates solitary wave propagation inside a fiber. As a result, twin couplers are the subject of this study. Kerr law is the sort of non-linearity addressed there. Because it offers solutions to problems with large tails or infinite fluctuations, the resulting...
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SDGs implementation, their synergies, and trade-offs in EU countries – Sensitivity analysis-based approach
PublicationSustainable development is one of the most urgent challenges facing humanity. Its basic principle is to improve people’s well-being and maintain it over time. In 2015, the United Nations approved 17 sustainable development goals (SDGs) to ensure a better and sustainable future for all, balancing economic, social and environmental development. SDGs create an ‘indivisible whole’; thus, examining their interactions is crucial. Our...
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DETERMINATION OF SURFACTANTS IN ENVIRONMENTAL SAMPLES - PART I. CATIONIC COMPOUNDS = Oznaczanie Surfaktantów W Próbkach Środowiskowych. Część I. Związki Kationowe
PublicationCompounds from the group of cationic surfactants are widely applied in household, industrial, cleaning, disinfectant, cosmetic and pharmaceutical products as their specific properties (antimicrobial, emulsifying, anticorrosion, softening). After use, cationic surfactants are disposed to wastewater-treatment plants and finally with effluent water to surface waters due to their incomplete degradation. Moreover, they can freely circulate...
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Honey antibacterial activity: A neglected aspect of honey quality assurance as functional food
PublicationBackground Honey is considered as a functional food with health-promoting properties. Its potent antibacterial and antibiofilm effects are the major attributes of so called ‘medical-grade honey’ which is topically used for the treatment of burns, wounds and skin disorders. Nevertheless, the current set of honey quality parameters adopted in the European Union do not include its biological properties. Furthermore, in light of the...
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Model-based identification of the dominant N2O emission pathway in a full-scale activated sludge system
PublicationActivated sludge models (ASMs), extended with an N2O emission module, are powerful tools to describe the operation of full-scale wastewater treatment plants (WWTPs). Specifically, such models can investigate the most contributive N2O production pathways and guide towards N2O and carbon footprint (CF) mitigation measures. A common practice is to develop and validate models using data from a single WWTP. In this study, a successfully...
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Accurate Modeling of Frequency Selective Surfaces Using Fully-Connected Regression Model with Automated Architecture Determination and Parameter Selection Based on Bayesian Optimization
PublicationSurrogate modeling has become an important tool in the design of high-frequency structures. Although full-wave electromagnetic (EM) simulation tools provide an accurate account for the circuit characteristics and performance, they entail considerable computational expenditures. Replacing EM analysis by fast surrogates provides a way to accelerate the design procedures. Unfortunately, modeling of microwave passives is a challenging...
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Low-cost performance-driven modelling of compact microwave components with two-layer surrogates and gradient kriging
PublicationUtilization of electromagnetic (EM) simulation tools has become indispensable for reliable evaluation of microwave components. As the cost of an individual analysis may already be considerable, the computational overhead associated with EM-driven tasks that require massive simulations (e.g., optimization) may turn prohibitive. One of mitigation methods is the employment of equivalent network models. Yet, they are incapable of accounting...
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Prediction of maximum tensile stress in plain-weave composite laminates with interacting holes via stacked machine learning algorithms: A comparative study
PublicationPlain weave composite is a long-lasting type of fabric composite that is stable enough when being handled. Open-hole composites have been widely used in industry, though they have weak structural performance and complex design processes. An extensive number of material/geometry parameters have been utilized for designing these composites, thereby an efficient computational tool is essential for that purpose. Different Machine Learning...
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Wykorzystanie narzędzi pracy zdalnej w działaniach Koła Naukowego Konstruktorów Pojazdów
PublicationNiniejszy artykuł stanowi opis działalności Koła Naukowego Konstruktorów Pojazdów, w którego działaniach wykorzystywane są nowoczesne narzędzia pracy zdalnej. Dzięki takiemu podejściu, możliwe staje się wyeliminowanie niedogodnień, z którymi borykano się stosując standardowe, starsze podejście do realizacji zadań projektowych w jednostkach badawczo-rozwojowych. Podane przykłady ilustrują, w jaki sposób powszechny obecnie dostęp...
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Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
PublicationEndometrial cancer (EC) is the second most common cancer in women. A large number of human cancers exhibit dysregulation of microRNA expression including EC. MiR-15b/16–2 is one of the best-known miRNA clusters that is expressed in many types of cancer tissues. Herein, we analyzed the expression of individual miR-15b/16–2 cluster members, its paralogues, and their target network analysis, as well as their prognostic significance...
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New Approaches for Escherichia coli Genotyping
PublicationEasy-to-perform, fast, and inexpensive methods of differentiation of Escherichia coli strains beyond the species level are highly required. Herein two new, original tools for genotyping of E. coli isolates are proposed. The first of the developed method, a PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) test uses a highly variable fliC gene, encoding the H antigen as a molecular target. The designing...
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Knowledge Risk Management in Organizations
PublicationPurpose – Shorter product life cycles, greater demands from consumers for sustainable and eco-friendly products and services, and thus the need for constant market observation make today’s business environment a rather complex one, the one that is characterized not only by a number of opportunities but also by a number of risks. These risks are increasingly related to knowledge which, in turn, underlines the need for an updated...
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Voltammetric and biological studies of folate-targeted non-lamellar lipid mesophases
PublicationFolate-targeted lipid nanostructures are promising strategies for the development of biocompatible drug delivery systems. The objective of this study was to evaluate the efficacy of drug delivery to cancer cells by folate-targeted lipid mesophases, cubosomes (CUB) and hexosomes (HEX), loaded with doxorubicin (DOX). Three cancer-derived cell lines (KB, HeLa, T98G) exhibiting different expressional levels of folate receptor protein...
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Sensitivity analysis as a tool to optimise Human Development Index
PublicationResearch background: Composite indicators are commonly used as an approximation tool to measure economic development, the standard of living, competitiveness, fairness, effectiveness, and many others being willingly implemented into many different research disciplines. However, it seems that in most cases, the variable weighting procedure is avoided or erroneous since, in most cases, the so-called...
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Street Art and Urban Regeneration. Case Study Gdansk and Rome.
PublicationStreet art plays an important role in urban planning as a transforming engine to regenerate the public spaces and in the processes of participation. The article analyzes two main topics. The first one focuses on the urban serving as a support for spatial and cultural strategies in urban redevelopment projects. The second one is related to the potential of micro urban interventions as a strategy for a wider involvement of inhabitants...
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Impacts on human health in the Arctic owing to climate-induced changes in contaminant cycling – The EU ArcRisk project policy outcome
PublicationResults of the EU ArcRisk project on human health impacts in the Arctic owing to climate-induced changes in contaminant cycling are summarized in the context of their policy application. The question on how will climate change affect the transport of selected persistent organic pollutants (POPs) and mercury, both to and within the Arctic has been addressed, as well as the issue of human health impacts of these pollutants in the...
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Modelling of Different Aeration Modes Influencing Processes in SBR Bioreactor
PublicationCurrently, computer modelling together with the simulation tools tailored for that purpose constitute a very important element in planning technological changes within wastewater treatment plant. From the point of view of the WWTP operator every modification should be introduced in order to improve the quality of treated sewage with the lowest financial outlays. These requirements can be met by using computer programmes to effectuate...
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Knowledge engineer – more than only technical position. The concept of knowledge engineering education at the Faculty of Management and Economics
PublicationOrganizational learning means an effective knowledge management. Management is nothing more than the constant decision-making. Therefore organizational learning must be seen through the prism of decisions taken at all levels. Unfortunately decisions are never taken within comfortable conditions. Decision maker suffers from a lack of any support. There is often a problem with human resources having right skills, sometimes they do...
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DATABASE AND BIGDATA PROCESSING SYSTEM FOR ANALYSIS OF AIS MESSAGES IN THE NETBALTIC RESEARCH PROJECT
PublicationA specialized database and a software tool for graphical and numerical presentation of maritime measurement results has been designed and implemented as part of the research conducted under the netBaltic project (Internet over the Baltic Sea – the implementation of a multi-system, self-organizing broadband communications network over the sea for enhancing navigation safety through the development of e-navigation services.) The...
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EM-Driven Size Reduction and Multi-Criterial Optimization of Broadband Circularly-Polarized Antennas Using Pareto Front Traversing and Design Extrapolation
PublicationMaintaining small size has become an important consideration in the design of contemporary antenna structures. In the case of broadband circularly polarized (CP) antennas, miniaturization is a challenging process due to the necessity of simultaneous handling of electrical and field properties (reflection, axial ratio, gain), as well as ensuring sufficient frequency range of operation, especially at the lower edge of the antenna...
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An adaptive-noise Augmented Kalman Filter approach for input-state estimation in structural dynamics
PublicationThe establishment of a Digital Twin of an operating engineered system can increase the potency of Structural Health Monitoring (SHM) tools, which are then bestowed with enhanced predictive capabilities. This is particularly relevant for wind energy infrastructures, where the definition of remaining useful life is a main driver for assessing the efficacy of these systems. In order to ensure a proper representation of the physical...
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Which transport policies increase physical activity of the whole of society? A systematic review
PublicationPurpose: There is strong evidence of the links between car-dependence and the physical inactivity pandemic. Physical inactivity accounts for 6–10% of major non-communicable diseases. Research consistently shows that unlike passive transport, active transport is associated with higher total daily physical activity (PA). While there are public policies that support PA in transport and, as a result, overall PA levels, the specific...
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Dynamic GPU power capping with online performance tracing for energy efficient GPU computing using DEPO tool
PublicationGPU accelerators have become essential to the recent advance in computational power of high- performance computing (HPC) systems. Current HPC systems’ reaching an approximately 20–30 mega-watt power demand has resulted in increasing CO2 emissions, energy costs and necessitate increasingly complex cooling systems. This is a very real challenge. To address this, new mechanisms of software power control could be employed. In this...
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Recent advances in high-frequency modeling by means of domain confinement and nested kriging
PublicationDevelopment of modern high-frequency components and circuits is heavily based on full-wave electromagnetic (EM) simulation tools. Some phenomena, although important from the point of view of the system performance, e.g., EM cross-coupling effects, feed radiation in antenna arrays, substrate anisotropy, cannot be adequately accounted for using simpler means such as equivalent network representations. Consequently, the involvement...
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Systematic review examining the evidence for impact of school policies on physical activity
PublicationBackground Epidemiological evidence has demonstrated that physical activity can have substantive health benefits for children and young people. The 'Policy Evaluation Network' is a multi-disciplinary research network across 7 European countries and New Zealand aimed at building capacity and evaluating the level of impact of policy interventions for promoting healthy lifestyles. The Toronto Charter identified 'whole-of-school' programmes...
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Effect of pH on optical sensing with poly-L-lysine-modified nanodiamonds
PublicationNitrogen-vacancy (NV) centers are crystallographic defects which provide diamonds with unique physical properties. The centers are known for their intensive, time-stable fluorescence, and an electron spin, which exhibits long coherence time and may be manipulated using external stimuli. Nanodiamonds containing the NV centers are promising tools in biolabeling, biosensing, and drug delivery due to the aforementioned properties of...
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Global EM-Driven Optimization of Multi-Band Antennas Using Knowledge-Based Inverse Response-Feature Surrogates
PublicationElectromagnetic simulation tools have been playing an increasing role in the design of contemporary antenna structures. The employment of electromagnetic analysis ensures reliability of evaluating antenna characteristics but also incurs considerable computational expenses whenever massive simulations are involved (e.g., parametric optimization, uncertainty quantification). This high cost is the most serious bottleneck of simulation-driven...
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Preliminary safety assessment of Polish interchanges
PublicationInterchanges are a key and the most complex element of a road infrastructure. The safety and functionality of interchanges determine the traffic conditions and safety of the entire road network. This applies particularly to motorways and express-ways, for which they are the only way to access and exchange traffic. A big problem in Poland is the lack of comprehensive tools for designers at individual stages of the design process....
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Modelling the impact of the agricultural holdings and land-use structure on the quality of inland and coastal waters with an innovative and interdisciplinary toolkit
PublicationThe changes taking place in the marine coastal zones are extremely important, as about 40% of the human population currently lives in the coastal areas (within 100 kilometres of the coastline) increasing anthropogenic pressure on the marine ecosystems. Agriculture is a significant source of nutrients to the marine environment that increase hypoxia, eutrophication and may pose a threat to the services provided by ecosystems. In...
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Data librarian and data steward – new tasks and responsibilities of academic libraries in the context of Open Research Data implementation in Poland
PublicationThesis/Objective – The policy of Open Access (OA) for researching resources in Europe has been implemented for more than 10 years. The first recommendations concerning providing OA to scientific materials were defined during the implementation of the 7th Framework Programme. Introducing another set of recommendations concerning OA to research data was the next stage. The recommendations were transformed into obligations under the...
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Structural analysis as a supporting method for the research of the medieval brick architecture
PublicationChronology of brick historical buildings might be established much more precisely than the chronology of stone ones due to the architectural and metrical analysis of bricks, mortars and brickworks. Comparison of historical sources allows to reconstruct the previous stages of constructing monuments. Causations between transformations and developments of monuments are usually interpreted as the results of artistic or ideological...
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Technical solutions and benefits of introducing rain gardens – Gdańsk case study
PublicationNowadays, Nature-Based Solutions (NBSs) are developing as innovative multifunctional tools to maximize urban ecosystem services such as storm water preservation, reduction of runoff and flood protection, groundwater pollution prevention, biodiversity enhancement, and microclimate control. Gdańsk is one of the first Polish cities to widely introduce rain gardens (one example of an NBS) in different areas such as parks, city center,...
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Analysis of the causes and effects of cyclist-pedestrian accidents in biggest Polish cities
PublicationTraffic incidents between pedestrians and cyclists result in an incomparably smaller number of victims (injured and killed) than accidents between unprotected traffic participants and other vehicles. However, such incidents cannot be underestimated, as in most cases they take place on elements of infrastructure designed for pedestrians and cyclists, and thus negatively affect the sense of safety of users in places where they...
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MODELOWANIE WYBRANYCH MIAR BEZPIECZEŃSTWA RUCHU NA DŁUGICH ODCINKACH DRÓG
PublicationKażdego roku w wypadkach drogowych na świecie życie traci prawie 1,3 mln osób, co oznacza prawie niemal 3 tys. ofiar dziennie,. Tyle samo zabitych w ruchu drogowym odnotowujemy rocznie w Polsce. Ekonomiczne straty w wyniku tych wypadków wynoszą ok. 2% światowego PKB. W roku 2010 Organizacja Narodów Zjednoczonych (ONZ) przyjęła rezolucję pt. „Dekada działań na rzecz bezpieczeństwa ruchu drogowego na lata 2011 – 2020” rozpoczynającą...
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Should we seek further improvement of fluid film bearings - what for and how?
PublicationFluid film bearings have been extensively used in the industry because of their unbeatable durability and extremely low friction coefficient. Large bearings supporting shafts of huge and important rotating machines constitute a special group of fluid film bearings since the reliability of crucial systems, like for example electro-energetic system, rely on their trouble-free operation. Large thrust bearings, apart from enormous...
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Chapter 11 – Application of Chemical Sensors and Sensor Matrixes to Air Quality Evaluation
PublicationIndoor and outdoor air quality is one of the key factors influencing human health. However, air quality evaluation is not easy task. Air is a complex system, which is subjected to changes even within short period of time. Progress in analytical methods and analytical tools provides increasingly more reliable information on the condition and quality of indoor and outdoor air. This progress, however, generates an increase in the...
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Automatic Threat Detection for Historic Buildings in Dark Places Based on the Modified OptD Method
PublicationHistoric buildings, due to their architectural, cultural, and historical value, are the subject of preservation and conservatory works. Such operations are preceded by an inventory of the object. One of the tools that can be applied for such purposes is Light Detection and Ranging (LiDAR). This technology provides information about the position, reflection, and intensity values of individual points; thus, it allows for the creation...
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The potential of urban agriculture in the revitalisation of a metropolis
PublicationIn Poland, the topic addressing urban areas of agricultural production and gardening activity is still viewed in two main blocks: 1) a shift of the urbanized zone’s boundaries, causing dispersion of suburban buildings as well as creates conflict zone between the residential area and the production and post-production zones; 2) a socially contentious issue of restructuring the inner-city complexes of former employee allotments....
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How Small KIBS Companies Manage Their Intellectual Capital? Towards an Emergent KM Approach
PublicationThe growing interest in Intellectual Capital management and Knowledge Management is now reaching small companies, especially those in the Knowledge-Intensive Business Services (KIBS) sector. This paper aims to explore this issue, starting from the assumption that a planned and systematic approach to KM, as is used in large companies, is rarely applicable in small organizations. It is more likely that small companies adopt an approach...
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ARTIFICIAL MODEL IN THE ASSESSMENT OF THE ALGORITHM OF OBJECTS RECORDED BY LASER SCANNING SHAPE DETECTION (ALS/TLS)
PublicationBrief description of the study and used methods. Brief description of the study and used As part of the preparatory work aimed to create the application solution allowing for the automation of searching objects in data, obtained in the scanning process using ALS (Airborne Laser Scanning) or TLS (Terrestrial Laser Scanning), the authors prepared a artificial (synthetic, theoretical) model of space, used for the verification of operation...
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Low-Cost Quasi-Global Optimization of Expensive Electromagnetic Simulation Models by Inverse Surrogates and Response Features
PublicationConceptual design of contemporary high-frequency structures is typically followed by a careful tuning of their parameters, predominantly the geometry ones. The process aims at improving the relevant performance figures, and may be quite expensive. The reason is that conventional design methods, e.g., based on analytical or equivalent network models, often only yield rough initial designs. This is especially the case for miniaturized...
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Time series analysis and impact assessment of the temperature changes on the vegetation and the water availability: A case study of Bakun-Murum Catchment Region in Malaysia
PublicationThe Bakun-Murum (BM) catchment region of the Rajang River Basin (RRB), Sarawak, Malaysia, has been under severe threat for the last few years due to urbanization, global warming, and climate change. The present study aimed to evaluate the time series analysis and impact assessment of the temperature changes on the vegetation/agricultural lands and the water availability within the BM region. For this purpose, the Landsat data for...
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Knowledge risks in organizations – Insights from companies
PublicationPurpose: Knowledge risks are increasingly becoming a great challenge to a variety of organizations. At the same time, academic research on such types of risks, their consequences, and potential ways of overcoming them is still scarce and fragmented. To fill this gap, the paper aims to find out do companies manage their knowledge risks, what are the possible knowledge risks they face and have they observed an increase of knowledge...
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Modeling of Passive and Forced Convection Heat Transfer in Channels with Rib Turbulators
PublicationThe main goal of the research presented in this paper was the experimental and numerical analysis of heat enhancement and aerodynamic phenomena during air flow in a channel equipped with flow turbulators in the form of properly configured ribs. The use of ribs intensifies the heat transfer and at the same time increases not only the flow resistance but also the energy costs. Therefore, designing modern heat exchangers with optimal...
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Long-Term Impact of Wind Erosion on the Particle Size Distribution of Soils in the Eastern Part of the European Union
PublicationWind erosion is the leading cause of soil degradation and air pollution in many regionsof the world. As wind erosion is controlled by climatic factors, research on this phenomenon isurgently needed in soil and land management in order to better adapt to climate change. In thispaper, the impact of wind erosion on the soil surface in relation to particle size distribution wasinvestigated. Changes in percentage of sand, silt and...
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Knowledge-based performance-driven modeling of antenna structures
PublicationThe importance of surrogate modeling techniques in the design of modern antenna systems has been continuously growing over the recent years. This phenomenon is a matter of practical necessity rather than simply a fashion. On the one hand, antenna design procedures rely on full-wave electromagnetic (EM) simulation tools. On the other hand, the computational costs incurred by repetitive EM analyses involved in solving common tasks...
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Making full and immediate Open Access a reality through the repository route – the role of open repositories in implementation of Plan S.
PublicationThesis/Objective: In 2018, research funding institutions associated in cOAlitionS issued PlanS document which aims to accelerate the transition to full and immediate Open Access to publications from publicly funded research until January 2021. Among the recommendations, which mainly relate to publishing in the Open Access model and its financing, there are also guidelines on the implementation of Plan S assumptions through the...
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Reduced-Cost Microwave Design Closure by Multi-Resolution EM Simulations and Knowledge-Based Model Management
PublicationParameter adjustment through numerical optimization has become a commonplace of contemporary microwave engineering. Although circuit theory methods are ubiquitous in the development of microwave components, the initial designs obtained with such tools have to be further tuned to improve the system performance. This is particularly pertinent to miniaturized structures, where the cross-coupling effects cannot be adequately accounted...
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Framework for Integration Decentralized and Untrusted Multi-vendor IoMT Environments
PublicationLack of standardization is highly visible while we use historical data sets or compare our model with others that use IoMT devices from different vendors. The problem also concerns the trust in highly decentralized and anonymous environments where sensitive data are transferred through the Internet and then are analyzed by third-party companies. In our research we propose a standard that has been implemented in the form of framework...