Search results for: SARS-COV-2 MAIN PROTEASE MPRO INHIBITION - Bridge of Knowledge

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Search results for: SARS-COV-2 MAIN PROTEASE MPRO INHIBITION

Search results for: SARS-COV-2 MAIN PROTEASE MPRO INHIBITION

  • Applications of Tensor Analysis in Continuum Mechanics

    Publication

    - Year 2018

    A tensor field is a tensor-valued function of position in space. The use of tensor fields allows us to present physical laws in a clear, compact form. A byproduct is a set of simple and clear rules for the representation of vector differential operators such as gradient, divergence, and Laplacian in curvilinear coordinate systems. The tensorial nature of a quantity permits us to formulate transformation rules for its components...

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  • Electrohydrodynamic flow patterns and collection efficiency in narrow wire-cylinder type electrostatic precipitator

    Publication

    - JOURNAL OF ELECTROSTATICS - Year 2013

    Recently, narrow electrostatic precipitators (ESPs) have become a subject of interest because of their possible application for the cleaning of the exhaust gases emitted by diesel engines. Diesel engines emit fine particles, which are harmful to human and animal health. There are several methods for decrease particulate emission from a diesel engines, but up to now, these methods are not enough effective or very expensive. Therefore,...

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  • Trust Management Method for Wireless Sensor Networks

    Publication

    - Year 2017

    A Wireless Sensor Network (WSN) is a network of spatially distributed autonomous sensors to monitor physical or environmental conditions, such as temperature, sound, pressure, etc. and to cooperatively pass their data to the main location. The first wireless network that bore any real resemblance to a modern WSN is the Sound Surveillance System (SOSUS), developed by the United States Military in the 1950s to detect and track Soviet...

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  • Genotyping Techniques for Determining the Diversity of Microorganisms

    Publication

    - Year 2012

    Typing of microbial pathogens, or identifying bacteria at the strain level, is particularly important for diagnosis, treatment, and epidemiological surveillance of bacterial infections. This is especially the case for bacteria exhibiting high levels of antibiotic resistance or virulence, and those involved in nosocomial or pandemic infections. Strain typing also has applications in studying bacterial population dynamics. The part...

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  • Spatial and vertical distribution analysis of heavy metals in urban retention tanks sediments: a case study of Strzyza Stream

    Publication

    Concentrations of seven heavy metals (HMs): Zn, Cu, Pb, Cd, Ni, Cr, and Fe in core samples of bottom sediments from four retention tanks (RTs) located along the Strzyza Stream in northern Poland (Gdansk) were measured to obtain a general view of sediment quality. The recognition of contamination and potential environmental impacts is the main aim of this paper. A total of 96 sediment samples were collected from eight sampling sites...

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  • Experimental investigation of the weight averaging of pulse frequency modulated sensor output signal

    Open Research Data
    open access

    The research aims to practically verify the results of theoretical analysis and simulations of the efficiency of weight averaging of pulse frequency modulated signal. For this purpose, a suitable test stand was built, and the control software in the LabVIEW environment was prepared. Then, a series of experiments were carried out to process and analyze...

  • Marcin Wekwejt dr inż.

    Marcin Wekwejt holds a bachelor’s degree in Biomedical Engineering (2016; J. and J. Śniadecki Bydgoszcz University of Technology & L. Rydygier Collegium Medicum), a master’s degree in Mechanical-Medical Engineering (2018; Gdańsk University of Technology & Gdańsk Medical University), and a PhD in Materials Engineering (2021; Gdańsk University of Technology). He was awarded the title of Doctor of Engineering and Technical...

  • Survey on opportunities and barriers in lighting controls

    Publication
    • B. B. Unzeta
    • J. de Boer
    • R. Delvaeye
    • B. Deroisy
    • M. Fontoynont
    • D. Geisler-Moroder,
    • N. Gentile,
    • T. Luo
    • D. N. Pimenta
    • P. Reinhold... and 5 others

    - Year 2021

    This report summarizes a survey performed in eight countries on the status quo of daylight and electric lighting control systems. Feedback from more than 100 international experts (building / facility managers and planers) was evaluated. The aim of the survey was to identify the perception of the different possibilities of the current lighting control solutions and the expectations about the control systems. The survey aims to...

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  • Theory and application of Near-infrared spectroscopy

    Publication

    - Year 2010

    In recent years one can observe a significant increase in the requirements on quality control in all industrial sectors. The growing number of involved analyses makes the traditional, time consuming, requiring use of large quantities of reagents, thus expansive methods inconvenient especially for industrial applications. Fortunately, there is a very fast, cheap and not invasive analytical method that is increasingly used in qualitative...

  • Water chemistry of tundra lakes in the periglacial zone of the Bellsund Fiord (Svalbard) in the summer of 2013

    Publication

    - SCIENCE OF THE TOTAL ENVIRONMENT - Year 2018

    Climate changes observed in the Arctic (e.g. permafrost degradation, glacier retreat) may have significant influence on sensitive polar wetlands. The main objectives of this paper are defining chemical features of water within six small arctic lakes located in Bellsund (Svalbard) in the area of continuous permafrost occurrence. The unique environmental conditions of the study area offer an opportunity to observe phenomena influencing...

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  • Hybrid electrode materials for fast performance devices

    Energy storage devices such as Electrochemical Double Layer Capacitors and other types of the electrochemical capacitors require chemically stable, non-soluble, electrochemically active electrode materials compatible with appropriate electrolytes. Factors which determine their applicability are derived from so called electrochemical window of electroltes, nature of charge accumulation and their kinetics. On the other hand technological...

  • METHODS OF TEACHING NOISE PROTECTION AT ENVIRONMENTAL ENGINEERING

    Publication

    Noise strongly influences both our health and behavior in everyday life and as employees or employers. The lost of hearing and other effects of noise on humans result not only in a significant decrease in the quality of life or work efficiency but have also have economic consequences. As noise can be preventable in part by the Environmental Engineers, but it is necessary to introduce them noise issues during their education process....

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  • Influence of external walls' thermal capacitance on indoor thermal comfort

    Publication

    - Year 2013

    The doctoral thesis presents the results of numerical investigations on the influence of walls’ thermal capacitance on indoor thermal comfort. A proper set of thermal parameters of a building structure can considerably limit the heating / cooling demand, and passively increase the indoor thermal comfort. However the effect of building thermal capacitance on indoor conditions is complex and not always beneficial. Among a great number...

  • The potential of urban agriculture in the revitalisation of a metropolis

    Publication

    - Year 2019

    In Poland, the topic addressing urban areas of agricultural production and gardening activity is still viewed in two main blocks: 1) a shift of the urbanized zone’s boundaries, causing dispersion of suburban buildings as well as creates conflict zone between the residential area and the production and post-production zones; 2) a socially contentious issue of restructuring the inner-city complexes of former employee allotments....

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  • A study of a compact high-efficiency zero-emission power plant with oxy-fuel combustion

    Publication

    - Year 2019

    This paper discusses the application of global trends in gas cycles technology using oxy-fuel combustion. This is followed by a demonstration of a design solution for a new cycle with two enhanced energy-converting devices, namely a wet combustion chamber and a spray-ejector condenser. The proposed gas and steam cycle unit is contained within a single turbine, whose benefits combine those offered by gas turbines (high inlet temperatures)...

  • Automatic Threat Detection for Historic Buildings in Dark Places Based on the Modified OptD Method

    Publication

    - ISPRS International Journal of Geo-Information - Year 2020

    Historic buildings, due to their architectural, cultural, and historical value, are the subject of preservation and conservatory works. Such operations are preceded by an inventory of the object. One of the tools that can be applied for such purposes is Light Detection and Ranging (LiDAR). This technology provides information about the position, reflection, and intensity values of individual points; thus, it allows for the creation...

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  • Study on polymer modified road asphalt mixture

    Publication

    - Year 2017

    The formulation of ternary asphalt-additives blend composed of crumb rubber : low-density polyethylene (CR : LDPE) and crumb rubber : textile fiber (CR : TF) couples, and quaternary asphalt additives-blend composed of (CR : LDPE : TF) triplets on the virgin asphalt to optimize the asphalt basic and rheological properties and to use the extrusion process of two or three additives to obtain composite materials of them, as well as...

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  • Od Safony do Sibylli : o twórczości kobiet, które miały odwagę zmieniać świat

    Publication

    - Year 2015

    "From Sappho to Sibylla. About the women’s research and literary output preserved in the PAS Gdańsk Library early printed books collection (15th-18th c.)" The main purpose of this study was to present women’s research and literary output preserved in the early printed books collection (15th-18th c.) of the PAS Gdańsk Library (PAN Biblioteka Gdańska). The author mentions the phenomenon of women writing and participation in the...

  • The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics

    The II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...

  • Tensile and flexural moduli for human orbital wall bones – comparative study

    The main aims of the current research were: (1) to analyze in detail the tensile modulus and ultimate tensile strength (UTS) of orbital wall bones separately for the left and right orbit of the same cadaver and (2) to compare the obtained results with a flexural modulus of the left and right orbit reported earlier by A. C. van Leeuwen et al. [14]. A set of 54 specimens of orbital superior and/or medial walls harvested from 16 human...

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  • System subwencjonowania jednostek samorządu terytorialnego w Polsce: dysfunkcje i pożądane kierunki racjonalizacji

    Publication

    - Year 2016

    Monografia poświęcona jest problematyce racjonalizacji subwencjonowania samorządu terytorialnego w Polsce. Jej głównym celem jest określenie roli i znaczenia subwencji w systemie finansowym jednostek samorządu terytorialnego. Za dysfunkcje w największym stopniu zniekształcające system subwencjonowania uznano: ― brak powiązania globalnej kwoty subwencji ogólnej ze składowymi budżetu państwa, ― pomijanie, przy ocenie potencjału...

  • Experimental Study of the Influence of Noise Level on the Uncertainty Value in a Measurement System Containing an Analog-to-Digital Converter

    Open Research Data
    open access

    For newly developed measuring systems it is easy to estimate type B uncertainties based on the technical data of the measuring modules applied. However, it is difficult to estimate A type un-certainties due to the unknown type and level of interferences infiltrating into the measuring sys-tem. This is a particularly important problem for measurements...

  • TF-IDF weighted bag-of-words preprocessed text documents from Simple English Wikipedia

    Open Research Data

    The SimpleWiki2K-scores dataset contains TF-IDF weighted bag-of-words preprocessed text documents (raw strings are not available) [feature matrix] and their multi-label assignments [label-matrix]. Label scores for each document are also provided for an enhanced multi-label KNN [1] and LEML [2] classifiers. The aim of the dataset is to establish a benchmark...

  • How to Meet the Green Deal Objectives—Is It Possible to Obtain 100% RES at the Regional Level in the EU?

    Publication

    - ENERGIES - Year 2022

    The subject matter discussed in the article concerns the problem of the energy transformation of the European Union (EU) countries. In the case of the EU, the energy transformation has specific characteristics due to formal legal and institutional provisions. This means that the member states are obliged to implement the adopted Community Energy Strategy, which was defined under the European Green Deal. According to the EU policy,...

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  • Literature review of user needs, toward user requirements

    Publication

    - Year 2020

    This report has been developed in the frame of the IEA SHC Task 61 Subtask A “User requirements”. The main objective was to rethink and reformulate user requirements to lighting (daylighting and electric lighting) in public buildings on the basis of a thorough literature study. The work is a joint effort of a number of scientists and represents collective knowledge in this topic. The concept of Lighting quality is the one, among...

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  • Comparison of different extraction techniques of polychlorinated biphenyls from sediments samples.

    In this work, problems that may occur during determination of trace levels of polychlorinated biphenyls in sediment samples are described. Main error sources are connected with extraction of analytes prior to final determination. During model studies, polychlorinated biphenyls have been extracted from sedimentreference material (METRANAL 2) with the use of different solvents (dichloromethane, hexsane, and toluene); the process...

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  • The particle method for simulation of self-organization phenomena

    Publication

    - Year 2011

    The aim of the work was to design, implement, and use, in a number of experiments, an abstract software environment (an artificial world)suitable for modelling systems consisting of many moving and interactingobjects distributed in space. The environment, named DigiHive, is directed towards modeling of complex systems manifested by processes of self-organization, self-reproduction and self modifications. The environment is mainly...

  • Development of Biocompatible Fe3O4@SiO2 Nanoparticles as Subcellular Delivery Platform for Glucosamine-6-phosphate Synthase Inhibitors

    Publication

    - Year 2018

    Numerous inhibitors of glucoseamine-6-phophate synthase (GlcN-6-P), the enzyme responsible from catalysis of the first step of metabolic pathway leading to metabolism 5’-diphospho-N-acetyl-D- glucosamine, were reported as effective agents for inhibiting the growth of various fungal pathogens. Among the reported inhibitors,...

  • Investigation of low-temperature cracks on selected national roads and motorways in Poland 2020

    Open Research Data
    open access

    The dataset contains video investigation and records of 68 road sections in various parts of Poland.  Videos were recorded with the use of two cameras: 1) mounted in front of measurement vehicle, which was focused on overall view of road and 2) which was focused on pavement surface. The records are categorized according to the ID of the section given...

  • Computer controlled systems - 2022/2023

    e-Learning Courses
    • P. Raczyński

    materiały wspierające wykład na studiach II stopnia na kierunku ACR pod tytułem komputerowe systemy automatyki 1. Computer system – controlled plant interfacing technique; simple interfacing and with both side acknowledgement; ideas, algorithms, acknowledge passing. 2. Methods of acknowledgement passing: software checking and passing, using interrupt techniques, using readiness checking (ready – wait lines). The best solution...

  • CCS-lecture-2023-2024

    e-Learning Courses
    • P. Raczyński

    materiały wspierające wykład na studiach II stopnia na kierunku ACR pod tytułem komputerowe systemy automatyki 1. Computer system – controlled plant interfacing technique; simple interfacing and with both side acknowledgement; ideas, algorithms, acknowledge passing. 2. Methods of acknowledgement passing: software checking and passing, using interrupt techniques, using readiness checking (ready – wait lines). The best solution optimization...