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Search results for: RES PROMOTION MECHANISMS
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MutL protein as a constituent of vsp, ner and mmr repair systems
PublicationMutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mis- match repair system (MMR). However, there is growing evidence that MMR system is not the only field of action for these pro- teins. Moreover, the participation in MMR does not even have to be their primary function. There are some reports indicat- ing involvement of MutL in BER, NER and VSP (very short patch repair)....
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MUTL PROTEIN AS A COMMON CONSTITUENT OF VSP, BER, NER AND MMR REPAIR SYSTEMS
PublicationMutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mismatch repair system (MMR). However, there is growing evidence that MMR system is not the only field of action of these proteins. Moreover, involvement in MMR does not even have to be their primary function. There are some reports indicating involvement of MutL in BER, NER and VSP (very short patch repair). MutL protein...
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Fully Separated Flow Control Using DBD Plasma Actuators Located at the Leading Edge of an Airfoil
PublicationIn the framework of the PLASMAERO European project, experiments were conducted to investigate the authority of surface DBD plasma actuators to alter a fully separated flow around an airfoil in order to improve its aerodynamic performances in its natural stall regime. In this paper, unsteady excitation control is more specifically investigated. The key control parameter studied here is the burst frequency which periodically imposes...
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An Overview of Image Analysis Techniques in Endoscopic Bleeding Detection
PublicationAuthors review the existing bleeding detection methods focusing their attention on the image processing techniques utilised in the algorithms. In the article, 18 methods were analysed and their functional components were identified. The authors proposed six different groups, to which algorithms’ components were assigned: colour techniques, reflecting features of pixels as individual values, texture techniques, considering spatial...
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Cell-penetrating peptides – mechanism of transduction and synthesis – short review
PublicationPotential antimicrobial agents may be effective if they are delivered efficiently to their site of action. In many cases, lack of permeability through the cell membrane is the main problem. One of the possible solutions could be a novel intracellular delivery system involving cell-penetrating peptides (CPPs), which may improve the efficiency of many new biophar-maceuticals. Among other things, CPPs are capable of trans-porting...
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BeesyCluster as Front-End for High Performance Computing Services
PublicationThe paper presents the BeesyCluster system as a middleware allowing invocation of services on high performance computing resources within the NIWA Centre of Competence project. Access is possible through both WWW and SOAP Web Service interfaces. The former allows non-experienced users to invoke both simple and complex services exposed through easyto-use servlets. The latter is meant for integration of external applications with...
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Ubiquity of client access in heterogeneous access environment
PublicationWith popularization of mobile computing and diverse offer of mobile devices providing functionality comparable to stationary computers, the necessity of providing network access for such users cannot be disputed. The requirement is further reinforced by emergence of general purpose mobile operating systems which provide their full functionality only with network connectivity available and popular XaaS (Anything as a Service) approach....
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Logical Interface for Soft Handover – an effective scheme of handovers in Proxy Mobile IPv6
PublicationMultimedia services are currently commonly available on mobile devices. Due to networks' convergence and migration to all-IP networks, mobility management at network layer is required. Moreover, nowadays it is popular to equip mobile devices with more than one wireless interface. Thus, soft handovers can be implemented, which means that an existing connection is removed after a new one is established. Usage of the Logical Interfaces...
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The properties, functions and use of selenium compounds in living organisms
PublicationSelenium occurs in the environment in inorganic and organic compounds. For many years it was regarded as a toxic element, causing numerous illnesses and diseases. But research in the last 50 years has revealed a "bright side" to this element, especially as a component of selenoproteins, selenium makes a significant contribution to the health of humans and animals. The selenium content in an organism depends on its concentration...
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Targeting shelterin proteins for cancer therapy.
PublicationAs a global health challenge, cancer prompts continuous exploration for innovative therapies that are also based on new targets. One promising avenue is targeting the shelterin protein complex, a safeguard for telomeres crucial in preventing DNA damage. The role of shelterin in modulating ataxia- telangiectasia mutated (ATM) and ataxia-telangiectasia and Rad3-related (ATR) kinases, key players in the DNA damage response (DDR),...
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Neural networks and deep learning
PublicationIn this chapter we will provide the general and fundamental background related to Neural Networks and Deep Learning techniques. Specifically, we divide the fundamentals of deep learning in three parts, the first one introduces Deep Feed Forward Networks and the main training algorithms in the context of optimization. The second part covers Convolutional Neural Networks (CNN) and discusses their main advantages and shortcomings...
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Free volume in physical absorption of carbon dioxide in ionic liquids: Molecular dynamics supported modeling
PublicationUnderstanding the mechanisms underlying the carbon dioxide (CO2) absorption in ionic liquids (ILs) is the key to their efficient utilization in industrial flue gas treatment. One of the parameters considered substantially important in the process is the Free Volume. In this study, the Fractional Free Volume (FFV) of 73 ILs was calculated using Molecular Dynamics (MD). A quantitative Structure-Property Relationship (QSPR) study...
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Directions and Prospects for the Development of the Electric Car Market in Selected ASEAN Countries
PublicationThe purpose of this article is to present the current situation and evaluate the opportuni‐ ties for the development of the electric car market in selected Southeast Asian countries in the con‐ text of the current situation in the rest of the world. Currently, the electric car market is at an ad‐ vanced stage of development in regions such as Western Europe, the USA, and China. It should be noted, however, that the number of electric...
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Fracture surface topography investigation and fatigue life assessment of notched austenitic steel specimens
PublicationThe objectives of this study were to investigate the fracture surface topography of X8CrNiS18-9 austenitic stainless-steel specimens for different loadings and notch radii and to supplement the knowledge about the fracture mechanisms for fatigue performance. Cases with three different values of the notch radius ρ and the stress amplitude σa were analysed. The fracture topographies were quantified by the areas over their entire...
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The role of low-energy electrons in the charging process of LISA test masses
PublicationThe estimate of the total electron yield is fundamental for our understanding of the test-mass charging associated with cosmic rays in the Laser Interferometer Space Antenna (LISA) Pathfinder mission and in the forthcoming gravitational wave observatory LISA. To unveil the role of low energy electrons in this process owing to galactic and solar energetic particle events, in this work we study the interaction of keV and sub-keV...
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HYDROGEN PRODUCTION PERFORMANCE IN THERMOCATALYTIC REACTOR BASED ON THE INTERMETALLIC PHASE OF NI3AL
PublicationThe main aim of the following paper is mathematical modelling for momentum, heat and mass transfer, which is accompanied by chemical surface reactions of the flow of the mixture helium and methanol. The thermocatalytic devices used for decomposition of hydrocarbons incorporate vertical microchannels coupling at the ends and heated to 500 oC at the walls. The results of the experiment were compared with CFD calculations to calibrate...
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A Study on Audio Signal Processed by "Instant Mastering"
PublicationAn increasing amount of music produced in home- and project-studios results in development and growth of "automatic mastering services". The presented investigation explores changes introduced to audio signal by various online mastering platforms. A music set consisting of 10 songs produced in small facilities was processed by eight on-line automatic mastering services. Additionally, some laboratory-constructed signals were tested....
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DUABI - Business Intelligence Architecture for Dual Perspective Analytics
PublicationA significant expansion of Big Data and NoSQL databases made it necessary to develop new architectures for Business Intelligence systems based on data organized in a non-relational way. There are many novel solutions combining Big Data technologies with Data Warehousing. However, the proposed solutions are often not sufficient enough to meet the increasing business demands, such as low data latency while still maintaining high...
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Artificial-Hand Technology—Current State of Knowledge in Designing and Forecasting Changes
PublicationThe subject of human-hand versatility has been intensively investigated for many years. Emerging robotic constructions change continuously in order to mimic natural mechanisms as accurately as possible. Such an attitude is motivated by the demand for humanoid robots with sophisticated end effectors and highly biomimic prostheses. This paper provides wide analysis of more than 80 devices that have been created over the last 40 years....
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Latest Insights on Novel Deep Eutectic Solvents (DES) for Sustainable Extraction of Phenolic Compounds from Natural Sources
PublicationPhenolic compounds have long been of great importance in the pharmaceutical, food, and cosmetic industries. Unfortunately, conventional extraction procedures have a high cost and are time consuming, and the solvents used can represent a safety risk for operators, consumers, and the environment. Deep eutectic solvents (DESs) are green alternatives for extraction processes, given their low or non-toxicity, biodegradability, and reusability....
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Phytoremediation—From Environment Cleaning to Energy Generation—Current Status and Future Perspectives
Publication:Phytoremediationis a technology based on the use of green plants to remove, relocate, deactivate, or destroy harmful environmental pollutants such as heavy metals, radionuclides, hydrocarbons, and pharmaceuticals. Under the general term of phytoremediation, several processes with distinctively different mechanisms of action are hidden. In this paper, the most popular modes of phytoremediation are described and discussed. A broad...
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THE APPLICATION OF THE MECHANOCHEMICAL SYNTHESIS FOR THE PREPARATION OF ADVANCED CERAMICS BASED ON BARIUM TITANATE
PublicationIn the present study, the lead-free BaTi1-xZrxO3 (for x = 0, 0.05 and 0.15) ceramics were prepared by High-Energy Ball Milling and heat treatments. The performed X-ray, SEM and EDS measurements confirmed high purity, good quality and the expected quantitative composition of the obtained samples. The study of dielectric properties was performed by means of broadband dielectric spectroscopy at the frequency ranging from 0.1 Hz to...
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Analiza sterowania ułamkowego PIλDμ mocą reaktora jądrowego
PublicationW artykule przedstawiono syntezę regulatora PIλDμ niecałkowitego rzędu dla potrzeb sterowania mocą reaktora jądrowego lekko wodnego określanego, jako typu PWR (Pressurized Water Reactor). W tym celu wykorzystano nieliniowy model matematyczny reaktora PWR o parametrach skupionych obejmujący procesy generacji i wymiany ciepła oraz termicznych efektów reaktywnościowych. Nastawy regulatora PIλDμ niecałkowitego rzędu dobrano w sposób...
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Metoda i algorytmy modyfikacji sygnału do celu wspomagania rozumienia mowy przez osoby z pogorszoną rozdzielczością czasową słuchu
PublicationPrzedmiotem badań przeprowadzonych w ramach rozprawy są metody modyfikacji czasu trwania sygnału (ang. Time Scale Modification –TSM) mowy operujące w czasie rzeczywistym oraz ocena ich wpływu na rozumienie wypowiedzi przez osoby z pogorszoną rozdzielczością czasową słuchu. Pogorszona rozdzielczość słuchu jest jednym z symptomów związanych z ośrodkowymi zaburzeniami słuchu (ang. Cetnral Auditory Processing Disorder – CAPD). W odróżnieniu...
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Analysis of IPv6 handovers in IEEE 802.16 environment
PublicationThe second generation of WiMAX solutions, based on IEEE 802.16-2005 standard, offers limited mobility support. Unfortunately, after quickly changing the point of attachment on the WiMAX data link layer (DLL), very slow and inefficient IPv6 reconfiguration takes place. Delays introduced by automatic configuration (DHCPv6 and IPv6 protocols) and Mobile IPv6 can easily diminish or even render useless all benefits gained using the...
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Direct electrical brain stimulation of human memory: lessons learnt and future perspectives
PublicationModulation of cognitive functions supporting human declarative memory is one of the grand challenges of neuroscience, and of vast importance for a variety of neuropsychiatric, neurodegenerative and neurodevelopmental diseases. Despite a recent surge of successful attempts at improving performance in a range of memory tasks, the optimal approaches and parameters for memory enhancement have yet to be determined. On a more fundamental...
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Leadership, culture, intellectual capital and knowledge processes for organizational innovativeness across industries: the case of Poland
PublicationPurpose – This study aims to present the overview of intellectual capital creation micro-mechanisms concerning formal and informal knowledge processes. The organizational culture, transformational leadership and innovativeness are also included in the investigation as ascendants and consequences of the focal relation of intellectual capital and knowledge processes. Design/methodology/approach – Based on a sample of 1,418 Polish...
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Wykorzystanie mediów społecznościowych do promocji otwartości w badaniach naukowych na przykładzie Biblioteki Politechniki Gdańskiej
PublicationMedia społecznościowe są jednym ze sposobów na skuteczną promocję zasobów oraz usług bibliotecznych w obecnym świecie cyfrowym. Stanowią również niedocenianą możliwość komunikacji pomiędzy naukowcami, bibliotekarzami a czytelnikami. Biblioteka akademicka może aktywnie angażować się w proces upowszechniania dorobku naukowego uczelni, podejmując w tym celu różnorakie działania marketingowe, wykorzystując takie serwisy jak: Facebook,...
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A survey of strategies for communication networks to protect against large-scale natural disasters
PublicationRecent natural disasters have revealed that emergency networks presently cannot disseminate the necessary disaster information, making it difficult to deploy and coordinate relief operations. These disasters have reinforced the knowledge that telecommunication networks constitute a critical infrastructure of our society, and the urgency in establishing protection mechanisms against disaster-based disruptions. Hence, it is important...
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RECODIS: Resilient Communication Services Protecting End-user Applications from Disaster-based Failures
PublicationDisaster-based failures can seriously disrupt any communication network, making its services unavailable. Such disruptions may be caused by natural disasters, technology-related failures, or malicious attacks, and they are observably increasing in number, intensity and scale. When network services that are a part of critical infrastructure become unavailable, commercial and/or societal problems are inevitable. The issue of limiting...
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Application tool for IP QoS network design
PublicationDespite the fact that differentiated-service-aware network implementation has been a widely discussed topic for quite some time, network design still proofs nontrivial. Well developed software could put an end to network designer's problems. This chapter describes work, which has been aimed at creating a comprehensive network design tool, offering a fair range of functionality and high reliability. The presented tool is able to...
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POSSIBILITY OF IDENTIFICATION OF TECHNICAL CONDITION OF BEARINGS FOR SELF-IGNITION ENGINES BY APPLICATION OF ACOUSTIC EMISSION AS A DIAGNOSTIC SIGNAL
PublicationThis paper presents the results of empirical studies where the acoustic emission (AE) method was applied to identify the technical condition of sliding surfaces of main and crank bearings for main diesel engines. The test results indicate that the measurements of the AE parameters allow the technical condition identification for bearings of this type. The results refer to the measurements of the parameters for AE generated in the...
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Types of wear and tear of biomaterials used in orthopaedic surgery
PublicationPurpose of this paper is presentation of observations on different kinds of wear and tear of biomaterials used in contemporary orthopaedic surgery. Types of prosthesis damage, encountered in medical practice, and their causes have been described. Results of many clinical studies were analysed to review prosthesis damage from the stage of implanting (such as intrusion of a foreign object between its components) to their natural...
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A non-adiabatic wavepacket dynamical study of the low energy chargetransfer process in the S3+ + H collision
PublicationThe collisional system S3+ + H?S2+ + H+ has been studied using a time-dependent wavepacket methodologyin two-dimensions. Using available potential energy surfaces and coupling matrix elementsobtained from multireference ab initio calculations, five non-adiabatically coupled electronic states of1P symmetry have been included in the dynamical simulations. The collision has been studied in thelow energy regime of 1-10 eV. The wavepacket...
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Protection in elastic optical networks
PublicationIn this article, we analyze gains resulting from the use of EON architectures with special focus on transportation of cloud-ready and content-oriented traffic in the context of network resilience. EONs are a promising approach for future optical transport networks and, apart from improving the network spectral efficiency, bring such new capabilities as squeezed protection, which reduces resource requirements in failure scenarios....
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Extending GQM by argument structures
PublicationEffective metrics definition methods are of particular importance, as measurement mechanisms are indispensable in virtually any engineering discipline. The paper describes how the well known Goal-Question-Metric (GQM) method of systematic metrics derivation from measurement goals can be extended by applying argument structures. The proposed approach is called Goal-Argument-Metric (GAM). We briefly introduce general ideas of GQM...
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Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays
PublicationMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds. The effects of the above-mentioned human impact on the environment not only can be noticed in the homeostasis disturbance in ecosystems, but they are also visible with respect to human. The high incidence...
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Hybrid DUMBRA: an efficient QoS routing algorithm for networks with DiffServ architecture
PublicationDynamic routing is very important issue of current packet networks. It may support the QoS and help utilize available network resources. Unfortunately current routing mechanisms are not sufficient to fully support QoS. Although many research has been done in this area no generic QoS routing algorithm has been proposed that could be used across all network structures. Existing QoS routing algorithms are either dedicated to limited...
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Extending GQM by Argument Structures
PublicationEffective methods for metrics definition are of particular importance, as measurement mechanisms are indispensable in virtually any engineering discipline. The paper describes how the well known Goal-Question-Metric (GQM) method of systematic metrics derivation from measurement goals can be extended by applying argument structures. The proposed approach is called Goal-Argument-Metric (GAM). The general ideas of GQM and GAM are...
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Nowe możliwości generowania zarysów satelitowych mechanizmów roboczych
PublicationPlanetary hydraulic gear motors have been well known since 70's . first motors were constructed for maritime industry by hydroster from gdansk. the evolution of this type of motors led to an increase of nominal pressure and durability. nowadays the industry needs reliable and efficient motor able to work with alternative hydraulic fluids like water, emulsion and vegetable oil. therefore a new type of motors are being developed...
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Electricity Supplier Switching Process in Poland – a Process Based on the General Distribution Agreement
PublicationPoland, as a Member State of the European Union, is committed to respect the common rules on the electricity market, among other things. One of the most important examples of these regulations is the perception of energy as a commodity subject to competitive market mechanisms. Competitive processes introduced in the national electricity market enable energy consumers, i.a., choice of electricity supplier under the TPA formula....
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Hydrological responses to large-scale changes in land cover of river watershed: Review
PublicationDespite many studies on the hydrological responses to forest cover changes in micro and mesoscale watersheds, the hydrological responses to forest cover alterations and associated mechanisms through the large spatial scale of the river watershed have not been comprehensively perceived. This paper thus reviews a wide range of available scientific evidence concerning the impacts exerted by the forest removal on precipitation, water...
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Carbon Nanomaterials From Metal-Organic Frameworks: A New Material Horizon for CO2 Reduction
PublicationThe rise of CO2 in the atmosphere, which results in severe climate change and temperature increase, is known as the major reason for greenhouse effect. Reducing CO2 to value-added products is an attractive solution to this severe problem, along with addressing the energy crisis, to which the catalysts being employed are of vital importance. Due to their high porosity and tunable compositions, Metal-Organic Frameworks (MOFs) show...
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Brand loyalty creation in the social network. Does the product category matter?
PublicationThe final goal of all marketers’ effort is to achieve a high level of loyalty toward their brands. Social network brand sites are increasingly attracting the attention of scientists and managers intrigued by their potential application for brand loyalty creation. The aim of this research, based on European sample, is to fill the gap in understanding the product category loyalty and brand loyalty relation as an output of brand identification...
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RESOURCE ALLOCATION IN DAB+ BROADCASTING SYSTEM
PublicationWith over two billion receivers operating worldwide, radio transmission is by far the most accessible medium. It has been a part of our lives since the 1920’s and has become one of the most trusted and friendly mass media. Today, its popularity is still strong, despite the outcome of many electronic media. In order to transform the radio into a viable medium of the 21st century, it will have to migrate from analogue to digital...
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Examples of Taxation on Real Estate Properties as an Long-term Investment Asset. Description of Situation in Selected European Countries
PublicationReal estate properties have become the alternative asset for long-term savings and investments. Such investment however is strictly related to risk inter alia taxation policy. The following article describes and discusses both theoretical and practical aspects of long-term investment taxation imposed on real estate market in selected European countries. The article presents the analyses of the taxes including its functions, mechanisms...
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Influence of the ionic strength on the amyloid fibrillogenesis of hen egg white lysozyme
PublicationThe study investigates the role of the electrostatic interactions in the fibrillation of the hen egg white lysozyme (HEWL). In order to achieve this aim the influence of the cations Na+, Mg2+ and Al3+ on the amyloid fibril formation and amorphous aggregation was tested. The amyloids are formed in the solution without added salt but the Thioflavin T fluorescence gives the false-negative result. In these conditions, the HEWL fibrils...
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A METHOD OF TRUST MANAGEMENT IN WIRELESS SENSOR NETWORKS
PublicationThe research problem considered in this paper is how to protect wireless sensor networks (WSN) against cyber-threats by applying trust management and how to strengthen network resilience to attacks targeting the trust management mechanism itself. A new method, called WSN Cooperative Trust Management Method (WCT2M), of distributed trust management in multi-layer wireless sensor networks is proposed and its performance is evaluated....
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Bee Products and Essential Oils as Alternative Agents for Treatment of Infections Caused by S. aureus
PublicationBacteria of the genus Staphylococcus are important human and veterinary pathogens. A crucial characteristic for this group of bacteria is that they can easily acquire mechanisms of antibiotic resistance for a plethora of antibiotics currently in use for human and animal therapies. Therefore, there is a great need to find novel, non-antibiotic chemotherapeutics with marked antistaphylococcal activity. Promising but still underestimated...
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Listening to Live Music: Life beyond Music Recommendation Systems
PublicationThis paper presents first a short review on music recommendation systems based on social collaborative filtering. A dictionary of terms related to music recommendation systems, such as music information retrieval (MIR), Query-by-Example (QBE), Query-by-Category (QBC), music content, music annotating, music tagging, bridging the semantic gap in music domain, etc. is introduced. Bases of music recommender systems are shortly presented,...