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Search results for: SYSTEM MODELS
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Antitumor Activity of Triazine Mimic Antibiotics for DNA-binding Implications (Impressive Activity in Vitro Against a Variety of Tumor Types in the NCI-60 Screen): NSC 710607 To Fight HCT-116 Human Colon Carcinoma Cell Lines in Vivo Using the Hollow Fiber Assay and Xenograft Mouse Models
PublicationPurpose Successful clinical applications of DNA-directed selective cytotoxic agents disrupt the vital replication/transcription processes and ultimately lead to cancer cell death. This study aimed to examine the growth screen of two lead triazine compounds in a number of cell lines and xenografts and to develop anticancer agents with noncovalent binding affinity bringing fewer side effects. Methods The NCI initial hollow...
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Framework for Integration Decentralized and Untrusted Multi-vendor IoMT Environments
PublicationLack of standardization is highly visible while we use historical data sets or compare our model with others that use IoMT devices from different vendors. The problem also concerns the trust in highly decentralized and anonymous environments where sensitive data are transferred through the Internet and then are analyzed by third-party companies. In our research we propose a standard that has been implemented in the form of framework...
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Parameter and delay estimation of linear continuous-time systems
PublicationIn this paper the problem of on-line identification of non-stationary delay systems is considered. Dynamics of supervised industrial processes is usually described by ordinary differential equations. Discrete-time mechanization of their continuous-time representations is based on dedicated finite-horizon integrating filters. Least-squares and instrumental variable procedures implemented in recursive forms are applied for simultaneous...
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Modeling BIM Objects From Point Clouds. Examples
PublicationThe article presents several ways to obtain BIM (Building Information Modeling) models from point clouds using standard commands in Revit 2018. In Revit geometric forms are possible to obtain in project, family or conceptual environments. Efficient modeling requires knowledge of methods of creating families and components in these environments and ways to combine them. Modeling methods with system and loadable families are presented,...
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Reliability of production machines in the bakery industry – theoretical and practical issues
PublicationThe aim of the article is to present probabilistic models, which were then used to analyze the reliability of production machines in the baking industry. The author conducted research in the period from January 2, 2016 to December 31, 2018 regarding the measurement of reliability of a traditional production system based on a probabilistic concept. Due to the limited scope of the article, reliability calculations for a set of thermo-oil...
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Integration, Processing and Dissemination of LiDAR Data in a 3D Web-GIS
PublicationThe rapid increase in applications of Light Detection and Ranging (LiDAR) scanners, followed by the development of various methods that are dedicated for survey data processing, visualization, and dissemination constituted the need of new open standards for storage and online distribution of collected three-dimensional data. However, over a decade of research in the area has resulted in a number of incompatible solutions that offer...
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New kinematic systems in single-sided lapping and their influence on lap wear
PublicationPrevious studies on one-sided lapping allow to state that not only parameters of lapping elements (i.e. properties of workpiece, abrasive grains and lapping plate) impact on a lapping efficiency. Influential are also kinematics and dynamics of the process. It is crucial to control an average velocity of lapping (v), a distribution of tangential acceleration (at), a nominal pressure (p), a lapping time (t) and disposal of workpiece...
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Modelling and simulations in time-fractional electrodynamics based on control engineering methods
PublicationIn this paper, control engineering methods are presented with regard to modelling and simulations of signal propagation in time-fractional (TF) electrodynamics. That is, signal propagation is simulated in electromagnetic media described by Maxwell’s equations with fractional-order constitutive relations in the time domain. We demonstrate that such equations in TF electrodynamics can be considered as a continuous-time system of...
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Performance and Power-Aware Modeling of MPI Applications for Cluster Computing
PublicationThe paper presents modeling of performance and power consumption when running parallel applications on modern cluster-based systems. The model includes basic so-called blocks representing either computations or communication. The latter includes both point-to-point and collective communication. Real measurements were performed using MPI applications and routines run on three different clusters with both Infiniband and Gigabit Ethernet...
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Integration of natural and artificial intelligence in production systems
PublicationIntegration processes play an increasingly important role in modern economy, and seriously co-decide about the effectiveness of the company. Integration phase occurs in the system life cycle by preceding the final stages of its implementation and activation. In turn, used in software engineering (SE) iteration-evolutionary models, such as spiral model make that the integration activities can occur in varying degrees in all phases...
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Verification of the Analytical Traffic Model of a Multidomain IMS/NGN Using the Simulation Model
PublicationIn this paper we verify the previously proposed analytical traffic model of a multidomain Next Generation Network (NGN), which is standardized for delivering multimedia services based on the IP Multimedia Subsystem (IMS). For this reason a proper simulation model used, in which not theoretical queuing system models but the operation of real network elements and standardized call scenarios are accurately implemented. Consequently,...
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Cough influence on fascia-mesh system built for a hernia repair - an experimental research
PublicationAn experimental approach to identify stronger and weaker fixation schemes in laparoscopic ventral hernia repair is presented in the paper. Two types of implants, whose mechanical properties are significantly different and five kinds of connectors are considered. Physical models of operated hernia have been built using those materials and porcine abdominal tissue. The models have been subjected to dynamic impulse load, similar to...
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Sensorless Field Oriented Control of Five Phase Induction Motor with Third Harmonic Injection
PublicationIn this paper, a sensorless field oriented control system of five-phase induction machine with the 3rd harmonic rotor flux is presented. Two vector models, α1-β1 and α3-β3, were transformed into d1-q1, d3-q3 models oriented in rotating frames, which correspond to the 1st and 3rd harmonic plane respectively. The authors proposed the linearization of the model in d-q coordinate frames by introducing a new variable “x” which is proportional...
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Procedure based proactive functional safety management for the risk mitigation of hazardous events in the oil port installations including insurance aspects
PublicationThis article addresses selected technical and organization aspects of risk mitigation in the oil port installations with regard to functional safety requirements specified in standards IEC 61508 and IEC 61511. The procedure for functional safety management includes the hazard identification, risk analysis and assessment, specification of overall safety requirements and definition of safety functions. Based on risk assessment results...
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MEASUREMENT O F HEALTHCARE SYSTEM EFFICIENCY IN OECD COUNTRIES
PublicationIncreased spending on healthcare systems in many countries tends to attract attention to their efficiency. The aim of this paper is to evaluate the efficiency of healthcare systems in the OECD countries and indicate causes of inefficiency by applying Data Envelopment Analysis (DEA) and using additive and super-efficiency models. The homogeneity of the sample is assessed and outliers are excluded. A ranking is established on the...
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Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression
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Effects of scatter plot initial solutions on regular grid facility layout algorithms in typical production models
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Fast Multi-Objective Optimization of Narrow-Band Antennas Using RSA Models and Design Space Reduction
PublicationComputationally efficient technique for multi-objective design optimization of narrow-band antennas is presented. In our approach, the corrected low-fidelity antenna model (obtained through coarse-discretization EM simulations) is enhanced using frequency scaling and response correction, sampled, and utilized to obtain a fast response surface approximation (RSA) antenna surrogate. The RSA model is constructed in the reduced design space....
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Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublicationMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
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Discrete-time predictive control design based on overparameterized delay-plant models and identified cancellation order.
PublicationPraca dotyczy uogólnionego sterowania predykcyjnego (GPC) obiektami opisanymi dyskretnoczasowymi modelami CARIMA z uproszczeniami (nieminimalnych, przeparametryzowanych) oraz o niezerowym opóźnieniu transportowym. Optymalne sterowanie predykcyjne wyznacza się na podstawie minimalnowariancyjnego oszacowania przyszłej odpowiedzi sterowanego obiektu. Poprzez analizę warunków rozwiązywalności zadania syntezy sterownika GPC, sformułowano...
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Initializing the EM Algorithm for Univariate Gaussian, Multi-Component, Heteroscedastic Mixture Models by Dynamic Programming Partitions
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Improving the Accuracy of Automatic Reconstruction of 3D Complex Buildings Models from Airborne Lidar Point Clouds
PublicationDue to high requirements of variety of 3D spatial data applications with respect to data amount and quality, automatized, effcient and reliable data acquisition and preprocessing methods are needed. The use of photogrammetry techniques—as well as the light detection and ranging (LiDAR) automatic scanners—are among attractive solutions. However, measurement data are in the form of unorganized point clouds, usually requiring transformation...
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3D Morphable Models Application for Expanding Face Database Limited to Single Frontal Face Per Person
Publication1. Zaprezentowany materiał dotyczył badań nad rozszerzeniem dysponowanej bazy wzorców wizerunków twarzy, o dodatkowe wzorce z wariacją w ustawieniu. Dodatkowe wzorce były usyskiwane poprzez przejście z wizerunku twarzy 2D na model 3D, zasymulowanie zadanego ustawienia i powrót do dziedziny 2D (poprzez rzutowanie 3D->2D). W fazie konstrukcji modelu 3D, z wizerunku 2D była ściągana zarówno tekstura twarzy jak i siatka punktów charakterystycznych....
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Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach
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On the usefulness of selected radio waves propagation models for designing mobile wireless systems in container terminal environment
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Application of computational intelligence models in IoMT big data for heart disease diagnosis in personalized health care
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Impact of Feature Selection Methods on the Predictive Performance of Software Defect Prediction Models: An Extensive Empirical Study
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Three-Dimensional Models of Liver Vessels for Navigation during Laparotomic Attenuation of Intrahepatic Portosystemic Shunt in Dogs
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Selected mice models based on APP, MAPT and presenilin gene mutations in research on the pathogenesis of Alzheimer’s disease
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Minimizing Distribution and Data Loading Overheads in Parallel Training of DNN Acoustic Models with Frequent Parameter Averaging
PublicationIn the paper we investigate the performance of parallel deep neural network training with parameter averaging for acoustic modeling in Kaldi, a popular automatic speech recognition toolkit. We describe experiments based on training a recurrent neural network with 4 layers of 800 LSTM hidden states on a 100-hour corpora of annotated Polish speech data. We propose a MPI-based modification of the training program which minimizes the...
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Experimental validation of pressure drop models during flow boiling of R134a – effect of flow acceleration and entrainment
PublicationA crucial step to assure proficient work of power and process apparatus is their proper design. A wide array of those devices operates within boiling or condensation of the working fluid to benefit from high heat transfer rates. Two-phase flows are associated with high heat transfer coefficients because of the latent heat of evaporation and high turbulence level between the liquid and the solid surface. Predicting heat transfer...
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A Method for the Evaluation of Urban Freight Transport Models as a Tool for Improving the Delivery of Sustainable Urban Transport Policy
PublicationThe article presents a method which helps local authorities to evaluate urban freight transport models. Given the complex requirements for input data and the inability to supply them for most cities, a proper quantitative evaluation of model functionality may be quite difficult for local authorities. Freight transport models designed to support sustainable urban freight transport objectives are a particular example. To overcome...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Improving Accuracy of Respiratory Rate Estimation by Restoring High Resolution Features With Transformers and Recursive Convolutional Models
PublicationNon-contact evaluation of vital signs has been becoming increasingly important, especially in light of the COVID- 19 pandemic, which is causing the whole world to examine people’s interactions in public places at a scale never seen before. However, evaluating one’s vital signs can be a relatively complex procedure, which requires both time and physical contact between examiner and examinee. These re- quirements limit the number...
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A Cost-Effective Method for Reconstructing City-Building 3D Models from Sparse Lidar Point Clouds
PublicationThe recent popularization of airborne lidar scanners has provided a steady source of point cloud datasets containing the altitudes of bare earth surface and vegetation features as well as man-made structures. In contrast to terrestrial lidar, which produces dense point clouds of small areas, airborne laser sensors usually deliver sparse datasets that cover large municipalities. The latter are very useful in constructing digital...
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Constructing genuinely entangled multipartite states with applications to local hidden variables and local hidden states models
PublicationBuilding upon the results of R. Augusiak et al. [Phys. Rev. Lett. 115, 030404 (2015)] we develop a general approach to the generation of genuinely entangled multipartite states of any number of parties from genuinely entangled states of a fixed number of parties, in particular, the bipartite entangled ones. In our approach, certain isometries whose output subspaces are either symmetric or genuinely entangled in some multipartite...
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Results of the application of tropospheric corrections from different troposphere models for precise GPS rapid static positioning
PublicationIn many surveying applications, determination of accurate heights is of significant interest. The delay caused by the neutral atmosphere is one of the main factors limiting the accuracy of GPS positioning and affecting mainly the height coordinate component rather than horizontal ones. Estimation of the zenith total delay is a commonly used technique for accounting for the tropospheric delay in static positioning. However, in the...
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Surface sliding in human abdominal wall numerical models: Comparison of single-surface and multi-surface composites
PublicationDetermining mechanical properties of abdominal soft tissues requires a coupled experimental-numerical study, but first an appropriate numerical model needs to be built. Precise modeling of human abdominal wall mechanics is difficult because of its complicated multi-layer composition and large variation between specimens. There are several approaches concerning simplification of numerical models, but it is unclear how far one could...
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Volatile Compound Emissions from Stereolithography Three-Dimensional Printed Cured Resin Models for Biomedical Applications
PublicationStereolithography three-dimensional printing is used increasingly in biomedical applications to create components for use in healthcare and therapy. The exposure of patients to volatile organic compounds (VOCs) emitted from cured resins represents an element of concern in such applications. Here, we investigate the biocompatibility in relation to inhalation exposure of volatile emissions of three different cured commercial resins...
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A new anisotropic bending model for nonlinear shells: Comparison with existing models and isogeometric finite element implementation
PublicationA new nonlinear hyperelastic bending model for shells formulated directly in surface form is presented, and compared to four existing prominent bending models. Through an essential set of elementary nonlinear bending test cases, the membrane and bending stresses of each model are examined analytically. Only the proposed bending model passes all the test cases, while the other bending models either fail or only pass the test cases for...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Application of Msplit method for filtering airborne laser scanning data sets to estimate digital terrain models
PublicationALS point cloud filtering involves the separation of observations representing the physical terrain surface from those representing terrain details. A digital terrain model (DTM) is created from a subset of points representing the ground surface. The accuracy of the generated DTM is influenced by several factors, including the survey method used, the accuracy of the source data, the applied DTM generation algorithm, and the survey...
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Cobalt(II) tri-tert-butoxysilanethiolates: in search of models for catalytic metal site of liver alcohol dehydrogenase
PublicationPrzeprowadzono syntezę trzech kompleksów: [Co{SSi(OBut)3}2(NH3)(L-pic)],[Co{SSi(OBut)3}2(NH3)2]xMeCN i [Co{SSi(OBut)3}3(H2O)][NHEt3]. Kompleksy są monomeryczne, dla nich wyznaczono strukturę krystalograficzną. Kompleks [Co{SSi(OBut)3(NH3)(L-pic)] o rdzeniu CoN2OS2 posiada dwa różne ligandy azotowe, zaś [Co{SSi(OBut)3(L-pic)] stanowi substrat do syntezy związku modelującego centrum katalityczne LADH.
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Comparison of continuous and discontinuous constitutive models to simulate concrete behaviour under mixed mode failure conditions
PublicationW artykule porównano modele MES ciągłe i nieciągłe do symulacji zachowania betonu w warunkach mieszanego zniszczenia. W ramach modeli ciągłych zastosowano modele sprężysto-plastyczne oraz modele z redukcją sztywności sprężystej i nielokalnym osłabieniem. W ramach modeli nieciągłych zastosowano XFEM. Przedmiotem obliczeń były strefy lokalizacji i rysy w warunkach mieszanego zniszczenia wg testu doświadczalnego Nooru-Mohameda.
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FE-analysis of the beaviour of concrete elements with coupled elasto-plastic-damage models with non-local softening
PublicationArtykuł omawia wyniki symulacji zachowania sie elementów betonowych poddanych cyklicznemu obciążeniu. Do symulacji zastosowano połączone modele sprężysto-plastyczne z degradacją sztywności i z nielokalnym osłabieniem. Wyniki symulacji porównano z doswiadczeniami.
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FE-modelling of concrete behaviour under mixed mode conditions with non-local and cohesive constitutive models.
PublicationW artykule przedstawiono wyniki symulacji rys zaokrąglonych w elementach betonowych w warunkach mieszanego sposobu obciążenia. Symulacje wykonano przy zastosowaniu modelu rys kohezyjnych i modeli mechaniki ośrodka ciągłego z nielokalnym osłabieniem.. Wyniki symulacji porównano z doświadczeniami.
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Application of enhanced elasto-plastic damage models to concrete under quasi-static and dynamic cyclic loading
PublicationArtykuł omawia wyniki symulacji zachowania sie elementów betonowych poddanych zginaniu w czasie cyklicznego obciążenia. Do symulacji zastosowano 3 połączone modele sprężysto-plastyczne z degradacją sztywności i z nielokalnym osłabieniem. Wyniki symulacji porównano bezpośrednio z doświadczeniami.
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Limits of enhanced of macro- and meso-scale continuum models for studying size effect in concrete under tension
PublicationThe paper investigates a mechanical quasi-static size effect in concrete during splitting tension at the macro- and meso-level. In experiments, five different diameters of cylindrical concrete specimens were tested. Twodimensional plane strain finite element (FE) simulations were carried out to reproduce the experimental size effect. The size effect in experiments by Carmona et al. was also simulated. Two enhanced continuum concrete...
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Proportional-Derivative and Model-based Controllers used for a Serial Type Manipulator in case of a Variable Mass Payload
PublicationIn the paper, numerical analysis of dynamics of a variable mass system is considered. Its reference example is a serial-like manipulator composed of revolute joints and rigid bodies. Payload of its gripper is considered as its variable mass element (mass and inertia irregularly between subsequent payloads). For the rest of the system, inertia parameters are considered as known (precisely identified during the assembling process)....
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Enhancement of the Brayton cycle efficiency by water or steam utilization
PublicationIn the paper, thermodynamic analysis of two modifications of a Brayton cycle into enhancement cycles with water/steam injection are discussed. The first one deals with a STIG modified system with both interstage compressed air cooling and air heating (heat regeneration) before combustion chamber. The second one, mainly devoted to higher steam/air ratio, is connected with separate steam production in a HRSG. The analysis has been...