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The psychrotrophic yeast Sporobolomyces roseus LOCK 1119 as a source of a highly active aspartic protease for the in vitro production of antioxidant peptides
PublicationA psychrotrophic yeast strain producing a cold-adapted protease at low temperature was classified as Sporobolomyces roseus. In standard YPG medium, S. roseus LOCK 1119 synthesized an extracellular protease with an activity of approximately 560 U/L. Optimization of medium composition and process temperature considerably enhanced enzyme biosynthesis; an approximate 70% increase in activity (2060 U/L). The native enzyme was purified...
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Comparative Study on Assisted Solvent Extraction Techniques for the Extraction of Biologically Active Compounds from Sideritis raeseri and Sideritis scardica
PublicationThe plants in the Sideritis genus are postulated to exhibit several important medicinal properties due to their unique chemical composition. To isolate the targeted phytochemical compounds, the selection of a suitable extraction method is of primary importance. In this work, a comparative study on the phytochemical profiles of various Sideritis raeseri and Sideritis scardica extracts has been carried out. An untargeted metabolomics...
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Photoluminescence of partially reduced Eu2+/Eu3+ active centers in a NaF–Al2O3–P2O5 glassy matrix with tunable smooth spectra
PublicationIn this work, a series of photoluminescent materials have been synthesized based on optically transparent and chemically stable glasses of the nominal composition Na3Al2(PO4)2F3 (NaF–Al2O3–P2O5 system) doped with 1 wt% of europium. It has been shown that the synthesis conditions (mainly the temperature and duration of the melting stage under reducing conditions) strongly affected the photoluminescence spectra of the material. This...
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Przydatność białka rybiego w postaci kolagenu lub żelatyny oraz polisacharydu - kapa-karagenu do wytwarzania aktywnych opakowań biodegradowalnych = Usefulness of fish collagen, gelatin and carrageenan for preparation of active biodegradable packages
PublicationSummary - The possibility of use of protein films made of fish collagen or gelatin as well as polysaccharide carrageenan films as carriers of enzymes (lysozyme or lysostaphyne), for preparation of microbiologically active packages, was investigated. It was found that crosslinking of such systems with N-[3(dimethylamino)propyl]-N'-ethylcarboimide (EDC) does not influence the activity of lysozyme immobilized in the films (Table 1)....
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Grzegorz Boczkaj dr hab. inż.
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Improving Accuracy of Respiratory Rate Estimation by Restoring High Resolution Features With Transformers and Recursive Convolutional Models
PublicationNon-contact evaluation of vital signs has been becoming increasingly important, especially in light of the COVID- 19 pandemic, which is causing the whole world to examine people’s interactions in public places at a scale never seen before. However, evaluating one’s vital signs can be a relatively complex procedure, which requires both time and physical contact between examiner and examinee. These re- quirements limit the number...
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Data-driven models for fault detection using kernel PCA: A water distribution system case study
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Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression
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Effects of scatter plot initial solutions on regular grid facility layout algorithms in typical production models
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Application of computational intelligence models in IoMT big data for heart disease diagnosis in personalized health care
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Impact of Feature Selection Methods on the Predictive Performance of Software Defect Prediction Models: An Extensive Empirical Study
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MATHEMATICAL MODELS OF DUAL TRANSMISSIVITY AND EXAMPLES OF THEIR APPLICATION IN INTERPRETING PIEZOMETRIC TESTS CONDUCTED IN THE BEŁCHATÓW LIGNITE MINE
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Wybrane aspekty i zastosowania modeli zdarzeń ekstremalnych / Selected facets and application of models of extremal events
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Hybrid forecasting models for wind-PV systems in diverse geographical locations: Performance and power potential analysis
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On the usefulness of selected radio waves propagation models for designing mobile wireless systems in container terminal environment
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3D Morphable Models Application for Expanding Face Database Limited to Single Frontal Face Per Person
Publication1. Zaprezentowany materiał dotyczył badań nad rozszerzeniem dysponowanej bazy wzorców wizerunków twarzy, o dodatkowe wzorce z wariacją w ustawieniu. Dodatkowe wzorce były usyskiwane poprzez przejście z wizerunku twarzy 2D na model 3D, zasymulowanie zadanego ustawienia i powrót do dziedziny 2D (poprzez rzutowanie 3D->2D). W fazie konstrukcji modelu 3D, z wizerunku 2D była ściągana zarówno tekstura twarzy jak i siatka punktów charakterystycznych....
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Initializing the EM Algorithm for Univariate Gaussian, Multi-Component, Heteroscedastic Mixture Models by Dynamic Programming Partitions
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Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach
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Quantitative Soil Characterization for Biochar–Cd Adsorption: Machine Learning Prediction Models for Cd Transformation and Immobilization
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Discrete-time predictive control design based on overparameterized delay-plant models and identified cancellation order.
PublicationPraca dotyczy uogólnionego sterowania predykcyjnego (GPC) obiektami opisanymi dyskretnoczasowymi modelami CARIMA z uproszczeniami (nieminimalnych, przeparametryzowanych) oraz o niezerowym opóźnieniu transportowym. Optymalne sterowanie predykcyjne wyznacza się na podstawie minimalnowariancyjnego oszacowania przyszłej odpowiedzi sterowanego obiektu. Poprzez analizę warunków rozwiązywalności zadania syntezy sterownika GPC, sformułowano...
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Three-Dimensional Models of Liver Vessels for Navigation during Laparotomic Attenuation of Intrahepatic Portosystemic Shunt in Dogs
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Selected mice models based on APP, MAPT and presenilin gene mutations in research on the pathogenesis of Alzheimer’s disease
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Cobalt(II) tri-tert-butoxysilanethiolates: in search of models for catalytic metal site of liver alcohol dehydrogenase
PublicationPrzeprowadzono syntezę trzech kompleksów: [Co{SSi(OBut)3}2(NH3)(L-pic)],[Co{SSi(OBut)3}2(NH3)2]xMeCN i [Co{SSi(OBut)3}3(H2O)][NHEt3]. Kompleksy są monomeryczne, dla nich wyznaczono strukturę krystalograficzną. Kompleks [Co{SSi(OBut)3(NH3)(L-pic)] o rdzeniu CoN2OS2 posiada dwa różne ligandy azotowe, zaś [Co{SSi(OBut)3(L-pic)] stanowi substrat do syntezy związku modelującego centrum katalityczne LADH.
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Fast Multi-Objective Optimization of Narrow-Band Antennas Using RSA Models and Design Space Reduction
PublicationComputationally efficient technique for multi-objective design optimization of narrow-band antennas is presented. In our approach, the corrected low-fidelity antenna model (obtained through coarse-discretization EM simulations) is enhanced using frequency scaling and response correction, sampled, and utilized to obtain a fast response surface approximation (RSA) antenna surrogate. The RSA model is constructed in the reduced design space....
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Data-driven models for fault detection using kernel pca:a water distribution system case study
PublicationKernel Principal Component Analysis (KPCA), an example of machine learning, can be considered a non-linear extension of the PCA method. While various applications of KPCA are known, this paper explores the possibility to use it for building a data-driven model of a non-linear system-the water distribution system of the Chojnice town (Poland). This model is utilised for fault detection with the emphasis on water leakage detection....
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Application of Msplit method for filtering airborne laser scanning data sets to estimate digital terrain models
PublicationALS point cloud filtering involves the separation of observations representing the physical terrain surface from those representing terrain details. A digital terrain model (DTM) is created from a subset of points representing the ground surface. The accuracy of the generated DTM is influenced by several factors, including the survey method used, the accuracy of the source data, the applied DTM generation algorithm, and the survey...
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Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublicationMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
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Volatile Compound Emissions from Stereolithography Three-Dimensional Printed Cured Resin Models for Biomedical Applications
PublicationStereolithography three-dimensional printing is used increasingly in biomedical applications to create components for use in healthcare and therapy. The exposure of patients to volatile organic compounds (VOCs) emitted from cured resins represents an element of concern in such applications. Here, we investigate the biocompatibility in relation to inhalation exposure of volatile emissions of three different cured commercial resins...
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Machine-Learning-Based Global Optimization of Microwave Passives with Variable-Fidelity EM Models and Response Features
PublicationMaximizing microwave passive component performance demands precise parameter tuning, particularly as modern circuits grow increasingly intricate. Yet, achieving this often requires a comprehensive approach due to their complex geometries and miniaturized structures. However, the computational burden of optimizing these components via full-wave electromagnetic (EM) simulations is substantial. EM analysis remains crucial for circuit...
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Results of the application of tropospheric corrections from different troposphere models for precise GPS rapid static positioning
PublicationIn many surveying applications, determination of accurate heights is of significant interest. The delay caused by the neutral atmosphere is one of the main factors limiting the accuracy of GPS positioning and affecting mainly the height coordinate component rather than horizontal ones. Estimation of the zenith total delay is a commonly used technique for accounting for the tropospheric delay in static positioning. However, in the...
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Constructing genuinely entangled multipartite states with applications to local hidden variables and local hidden states models
PublicationBuilding upon the results of R. Augusiak et al. [Phys. Rev. Lett. 115, 030404 (2015)] we develop a general approach to the generation of genuinely entangled multipartite states of any number of parties from genuinely entangled states of a fixed number of parties, in particular, the bipartite entangled ones. In our approach, certain isometries whose output subspaces are either symmetric or genuinely entangled in some multipartite...
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Minimizing Distribution and Data Loading Overheads in Parallel Training of DNN Acoustic Models with Frequent Parameter Averaging
PublicationIn the paper we investigate the performance of parallel deep neural network training with parameter averaging for acoustic modeling in Kaldi, a popular automatic speech recognition toolkit. We describe experiments based on training a recurrent neural network with 4 layers of 800 LSTM hidden states on a 100-hour corpora of annotated Polish speech data. We propose a MPI-based modification of the training program which minimizes the...
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FE-analysis of the beaviour of concrete elements with coupled elasto-plastic-damage models with non-local softening
PublicationArtykuł omawia wyniki symulacji zachowania sie elementów betonowych poddanych cyklicznemu obciążeniu. Do symulacji zastosowano połączone modele sprężysto-plastyczne z degradacją sztywności i z nielokalnym osłabieniem. Wyniki symulacji porównano z doswiadczeniami.
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FE-modelling of concrete behaviour under mixed mode conditions with non-local and cohesive constitutive models.
PublicationW artykule przedstawiono wyniki symulacji rys zaokrąglonych w elementach betonowych w warunkach mieszanego sposobu obciążenia. Symulacje wykonano przy zastosowaniu modelu rys kohezyjnych i modeli mechaniki ośrodka ciągłego z nielokalnym osłabieniem.. Wyniki symulacji porównano z doświadczeniami.
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Application of enhanced elasto-plastic damage models to concrete under quasi-static and dynamic cyclic loading
PublicationArtykuł omawia wyniki symulacji zachowania sie elementów betonowych poddanych zginaniu w czasie cyklicznego obciążenia. Do symulacji zastosowano 3 połączone modele sprężysto-plastyczne z degradacją sztywności i z nielokalnym osłabieniem. Wyniki symulacji porównano bezpośrednio z doświadczeniami.
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Comparison of continuous and discontinuous constitutive models to simulate concrete behaviour under mixed mode failure conditions
PublicationW artykule porównano modele MES ciągłe i nieciągłe do symulacji zachowania betonu w warunkach mieszanego zniszczenia. W ramach modeli ciągłych zastosowano modele sprężysto-plastyczne oraz modele z redukcją sztywności sprężystej i nielokalnym osłabieniem. W ramach modeli nieciągłych zastosowano XFEM. Przedmiotem obliczeń były strefy lokalizacji i rysy w warunkach mieszanego zniszczenia wg testu doświadczalnego Nooru-Mohameda.
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Atmospheric Pressure Glow Discharges Generated in Contact with Flowing Liquid Cathode: Production of Active Species and Application in Wastewater Purification Processes
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Molecular geometry and optical activity of N-nitroso-2,2,6,6-tetramethylpiperidines generated by spontaneous crystallization and inclusion complexation with optically active diols
PublicationTrzy N-nitrozo-2,2,6,6-tetrametylopiperydyny, których chiralność wynika z utrudnionej rotacji wokół wiązania N-N posiadającego częściowy charakter wiązania podwójnego poddano badaniom stereochemicznym i spektroskopowym. Badane związki tworzą kompleksy inkluzyjne z optycznie czynnymi gospodarzami - Taddolami, w których N-nitrozo-2,2,6,6-tetrametylopiperydyny przyjmują chiralną konformację co dowodzą ich widma CD wykonane w ciele...
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Thioamides and selenoamides with chirality solely due to hindered rotation about the C-N bond: enantioselective complexation with optically active hosts
PublicationBariera rotacji wokół wiązania C-N w tioamidach jest średnio o 3-5 kcal/mol wyższa niż w odpowiednich amidach, a w analogicznych selenoamidach wzrasta jeszcze o 1 kcal/mol. Dzięki temu związki te występują w dwu enancjomerycznych formach, których wzajemna przemiana zachodzi w wyniku rotacji wokół wiązań C-N. Bariera rotacji jest wystarczająco wysoka, aby można było podjąć próbę ich rozdziału na enancjomery w temperaturze pokojowej....
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Interferometric optical fiber sensors with active stabilization of the operating point using a tunable semiconductor laser. Optical Fibres and Their Applications VIII.
PublicationW pracy przedstawiono wyniki badań światłowodowych interferometrycznych sensorów siły wykonanych w konfiguracji interferometru Michelsona i wykorzystujących aktywną stabilizację punktu pracy przy pomocy zmiany długości fali źródła. Porównano dwie klasy omawianych sensorów a następnie zrealizowano sensor. W konstrukcji sensora zastosowano modulator z pośrednim pomiarem siły. Mierzona siła jest zamieniana na ciśnienie hydrostatyczne,...
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Investigating COVID-19 active pharmaceutical ingredients (APIs) degradation using Peroxydisulfate/FeMnOx binary metal oxide/Ultrasound System
PublicationDegradation of Favipiravir using a hybrid system of peroxydisulfate, FeMnOx binary metal oxide, and ultrasound irradiation was studied. A novel catalyst was synthesized with deep eutectic solvent (DES). The effects of DES type on catalytic performance was evaluated and the catalysts were characterized using XRD, SEM, BET, XPS, and EDS. DES-based catalysts exhibited higher efficiency due to structure change, surface area enhancement...
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Promotion of MXene (Ti3C2Tx) as a robust electrocatalyst for oxygen evolution reaction via active sites of ZIF-67 - In situ mechanism investigations
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Experimental and Computational Fluid Dynamics Studies on Straight and U-Bend Double Tube Heat Exchangers with Active and Passive Enhancement Methods
PublicationIn this work, the authors wanted to demonstrate the possibility to increase the heat transfer efficiency by using simple wire coil inserts to create turbulent flow in the boundary layer as well as air blowing into the annulus of the pipe. Experimental investigations were carried out for four heat exchanger constructions, i.e., plain double tube, turbulized double tube, plain U-bend double tube, U-tube with turbulator, plain double...
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Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
PublicationProliferation and expansion of leukemia is driven by leukemic stem cells (LSCs). Multidrug resistance (MDR) of LSCs is one of the main reasons of failure and relapses in acute myeloid leukemia (AML) treatment. In this study, we show that maintaining HL-60 at low cell culture density or applying a 240-day treatment with anthrapyridazone (BS-121) increased the percentage of primitive cells, which include LSCs determining the overall...
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Parameters and statistics of models made for selected companies of the Warsaw Stock Exchange
Open Research DataFor the WIG, WIG20 and mWIG40 indices, no day, week or month statistically differs from the average level of the index, which indicates no anomalies. The situation is different only for the index of small companies. In the case of sWIG80, the mean values on Friday, week 5 and 6, and during January, February and June were statistically different at the...
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Improved-Efficacy EM-Driven Optimization of Antenna Structures Using Adaptive Design Specifications and Variable-Resolution Models
PublicationOptimization-driven parameter tuning is an essential step in the design of antenna systems. Although in many cases it is still conducted through parametric studies, rigorous numerical methods become a necessity if truly optimum designs are sought for, and the problem intricacies (number of variables, multiple goals, constraints) make the interactive approaches insufficient. The two practical considerations of electromagnetic (EM)-driven...
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Performance of various risk prediction models in a large lung cancer screening cohort in Gdańsk, Poland—a comparative study
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Human Wharton’s Jelly—Cellular Specificity, Stemness Potency, Animal Models, and Current Application in Human Clinical Trials
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Sensitivity analysis of simple random beam models by means of Monte Carlo Methods using Variance Reductions Techniques
PublicationA probabilistic sensitivity analysis of two nonlinear bar structures is presented. The analysis is carried out on the basis of the Monte Carlo method. The imperfections of the structures and the applied loads are adapted as random variables. Based on all of the generated input variables, an output response of the system is sought. Afterwards, a coefficient responsible for the structure failure is calculated and the limit state...
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Determination of an adequate number of competitive functional models in the square Msplit(q) estimation with the use of a modified Baarda’s approach
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