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Search results for: G.B. Bonifacio
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Nowa metoda wymiarowania żelbetowych słupów uzwojonych w ujęciu nowelizowanej normy PN-B-03264.
PublicationW artykule przedstawiono nową metodę wymiarowania słupów uzwojonych w ujęciu nowelizowanej normy PN-B-03264. Podano przyczyny wprowadzenia opisywanych w artykule zmian i przedstawiono wcześniejsze próby modyfikacji sposobu obliczania nośności słupów uzwojonych w ujęciu normowym. Przeprowadzono dyskusję wyników obliczeń uzyskiwanych za pomocą nowej metody na tle wyników uzyskiwanych za pomocą dotychczasowej metody normowej, oraz...
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Laser Welding of UNS S33207 Hyper-Duplex Stainless Steel to 6061 Aluminum Alloy Using High Entropy Alloy as a Filler Material
PublicationThe high entropy alloy (HEA) filler used during the fabrication method determines the reliability of HEAs for steel-aluminum dissimilar alloy configuration. HEAs have a direct impact on the formation of intermetallic compounds (IMC) formed by the interaction of iron (Fe) and aluminum (Al), and influence the size of the joint’s interaction zone. A novel welding process for Fe-Al alloy joints was developed to prevent the development...
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Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment
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Czujniki wielkości nieelektrycznych [moduł dyscyplinarny, do wyboru Grupy A i B] 2022/2023
e-Learning CoursesProwadzący: dr hab. inż. Grzegorz Lentka, prof. PG Terminy: ( 3 godz. x 5 spotkań online): 19.11 (sob.) g. 9:15 – 11:45 (3x 45 min + 15 min przerwy) 20.11 (ndz.) g. 9:15 – 11:45 (3x 45 min + 15 min przerwy) 17.12 (sob.) g. 9:15 – 11:45 (3x 45 min + 15 min przerwy) 18.12 (ndz.) g. 9:15 – 11:45 (3x 45 min + 15 min przerwy) 14.01 (sob.) g. 12:00 do 14:30 (3x 45 min + 15 min przerwy) Tematyka realizowanego przedmiotu obejmuje: Wprowadzenie...
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Physical, Chemical and Mechanical Properties of Novel Poly(Urethaneamideimide)s
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Molecular aspects of the interaction between amphotericin B and a phospholipid bilayer: molecular dynamics studies.
PublicationAmfoterycyna B jest antybiotykiem z grupy polienów makrolidowych. Stosowany jest on w leczeniu układowych infekcji grzybowych. Wiadomo że związek ten oddziałuje ze składnikami błon lipidowych i tworzy kanały. W przedstawianej pracy prezentowane są wyniki symulacji przeprowadzonej dynamiką molekularną układu składającego się z 200 cząsteczek lipidów DMPC i jednej cząsteczki amfoterycyny ułożonej na powierzchni błony. Z przeprowadzonej...
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Immune escape of B-cell lymphoblastic leukemic cells through a lineage switch to acute myeloid leukemia
PublicationAcute leukemia (AL) with a lineage switch (LS) is associated with poor prognosis. The predisposing factors of LS are unknown, apart from KMT2A rearrangements that have been reported to be associated with LS. Herein, we present two cases and review all 104 published cases to identify risk factors for LS. Most of the patients (75.5%) experienced a switch from the lymphoid phenotype to the myeloid phenotype. Eighteen patients (17.0%)...
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An investigation on the role of GMA grafting degree on the efficiency of PET/PP-g-GMA reactive blending: morphology and mechanical properties
PublicationGlycidyl methacrylate (GMA) has been grafted on polypropylene (PP) with the aid of styrene (St) comonomer, by changing dicumyl peroxide initiator content, GMA level, and St concentration. The performance of the resulting PP-g-GMA reactive material towards static and dynamic mechanical properties of poly (ethylene terephthalate) (PET) was monitored in terms of grafting reaction variables and compatibilizer content. Fourier transform...
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Analiza i realizacja sterowania serwonapędami w trzech osiach przez sterownik programowalny z wykorzystaniem opisu zadania poprzez G-KOD
PublicationObrabiarki sterowane komputerowo są obecnie powszechnie wykorzystywane w zautomatyzowanych procesach produkcji. Zadania realizowane przez te obrabiarki są najczęściej opisywane z wykorzystaniem G-kodu. W przypadku, gdy potrzebna jest realizacja jedynie podstawowych funkcji obrabiarki, a do takich należy realizacja ruchu narzędzia, nie zawsze istnieje potrzeba stosowania obrabiarek. Podstawowe funkcje sterowania z powodzeniem mogą...
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Evaluation of Sicilian landraces of broccoli (B. oleracea var. italica Plenck) for quality traits
PublicationBrassica oleracea L. var. italica Plenck is one of the most popular vegetables which belong to Brassicaceae family. It is getting attention as an important source of bioactive compounds such as glucosinolates, and many other phytochemicals. In the frame of the H2020 BRESOV project, we evaluated three landraces (‘Broccolo nero', ‘Ramoso calabrese' and ‘Sparaceddu') and two commercial F1 hybrid cultivars (‘Marathon' and ‘Naxos')....
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Numerical simulation of the influence of the selected factors on the performance of a concrete road barrier H2/W5/B
PublicationThis paper discuss the influence of selected factors on the performance of a concrete road barrier H2/W5/B. Modelling techniques of a concrete road safety system were briefly discussed. Comparison to the full scale crash test results has been shown. The concrete road safety barrier has been investigated for evaluation of the overall damage after collision under various initial conditions. The failure assessment criterion has been...
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Production and characterization of MWBNNT and B-doped SWCNT
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Persulfates to degrade a mixture of dyes (rhodamine B, methylene blue) in the presence of glucose and visible light
PublicationA treatment process utilizing visible-light-activated (Vis) persulfates (PS) in the presence of an organic promoter (glucose) was developed for the simultaneous decolorization of a rhodamine B (RhB) and methylene blue (MB) mixture. Various doses of glucose, PS concentrations, pH values, initial dye concentrations and process time were tested to find out the most appropriate parameters for degrading the RhB/MB mixture in the...
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Oprawy ze średniowiecznych rękopisów muzycznych w księgozbiorze Jana Bernarda Bonifacia = Medieval musical manuscript leaves as bookbindings in the book-collection of Giovanni Bernardino Bonifacio
PublicationNiniejsza praca zawiera analizę jakościową i ilościową zespołu analogów, składającego się z około 30 druków (XVI wiek), oprawionych w średniowieczne rękopisy muzyczne na pergaminie z zapisem neumatycznym (XIV/XV wiek) z księgozbioru Jana Bernarda Bonifacia (1517-1597), fundatora Biblioteki Rady Miejskiej w Gdańsku (Bibliotheca Senatus Gedanensis). W centrum interesowania autorki znalazły się wyżej wymienione oprawy, a w szczególności...
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Oprawy ze średniowiecznych rękopisów muzycznych w księgozbiorze Jana Bernarda Bonifacia = Medieval musical manuscript leaves as bookbindings in the book-collection of Giovanni Bernardino Bonifacio
PublicationNiniejsza praca zawiera analizę jakościową i ilościową zespołu analogów, składającego się z około 30 druków (XVI wiek), oprawionych w średniowieczne rękopisy muzyczne na pergaminie z zapisem neumatycznym (XIV/XV wiek) z księgozbioru Jana Bernarda Bonifacia (1517-1597), fundatora Biblioteki Rady Miejskiej w Gdańsku (Bibliotheca Senatus Gedanensis). W centrum interesowania autorki znalazły się wyżej wymienione oprawy, a w szczególności...
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Electrical safety in low-voltage DC microgrids with B-type residual current devices
PublicationResidual current devices (RCDs) are most popular devices used in low-voltage installations for protection against electric shock and fire. In cases of high risk of electric shock the application of RCDs is mandatory. Currently, the spread of local direct current (DC) microgrids is widely considered. This creates new challenges for protective systems, in particular those based on RCDs. The main purpose of the research is to test...
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Jager W., Marzahn G.: Mauerwerk. Bemessung nach DIN 1053-100
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Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods
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Synthesis and Characterization of Nitrogen-doped Carbon Nanotubes Derived from g-C3N4
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Matematyczne metody opracowania obserwacji geodezyjnych B (2023/2024 - lato)
e-Learning CoursesKurs do przedmiotu "Matematyczne metody opracowania obserwacji geodezyjnych B (2023/2024 - lato)" dla studentów kierunku geodezja i kartografia, II stopień, semestr III, 2023/2024 - lato
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Paweł Możejko dr hab.
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Late Aortic Remodeling after Endovascular Repair of Complicated Type B Aortic Dissection—TEVAR Protects Only the Covered Segment of Thoracic Aorta
PublicationIntroduction: TEVAR is the preferred way of treatment of complicated type B aortic dissection. The purpose of the study was to assess the impact of TEVAR on aortic remodelling in the thoracic and abdominal segment in long-term follow-up. Methods: 23 patients with complicated type B aortic dissection were treated by TEVAR in years 2004-2012 in our Department. Aortic remodelling was rated based on preoperative and final follow-up...
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B-ENT
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Diphosphinoboranes as Intramolecular Frustrated Lewis Pairs: P–B–P Bond Systems for the Activation of Dihydrogen, Carbon Dioxide, and Phenyl Isocyanate
PublicationHerein, we present the first example of the activation of small molecules by P-B-P bond systems. The reactivity study involves reactions of two selected diphosphinoboranes, (tBu2P)2BPh (1’) and (Cy2P)2BNiPr2 (2), that differ in terms of their structural and electronic properties for the activation of dihydrogen, carbon dioxide, and phenyl isocyanate. Diphosphinoborane 1’ activates H2 under very mild conditions in the absence of...
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Time-of-flight electron scattering from molecular hydrogen: Benchmark cross sections for excitation of the X1Σ+g→b3Σ+u transition
PublicationThe electron impact X1Σ+g to b3Σ+u transition in molecular hydrogen is one of the most important dissociation pathways to forming atomic hydrogen atoms, and is of great importance in modeling astrophysical and industrial plasmas where molecular hydrogen is a substantial constituent. Recently it has been found that the convergent close-coupling (CCC) cross sections of Zammit et al. [Phys. Rev. A 95, 022708 (2017)] are up to a factor...
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Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics
PublicationAmphotericin B is a lifesaving polyene antibiotic used in the treatment of systemic mycoses. Unfortunately, the pharmacological applicability of this drug is limited because of its severe toxic side effects. At the same time, the lack of a well-defined mechanism of selectivity hampers the efforts to rationally design safer derivatives. As the drug primarily targets the biomembranes of both fungi and humans, new insights into the...
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Empirical analysis of tree-based classification models for customer churn prediction
PublicationCustomer churn is a vital and reoccurring problem facing most business industries, particularly the telecommunications industry. Considering the fierce competition among telecommunications firms and the high expenses of attracting and gaining new subscribers, keeping existing loyal subscribers becomes crucial. Early prediction of disgruntled subscribers can assist telecommunications firms in identifying the reasons for churn and...
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Thermally activated natural chalcopyrite for Fenton-like degradation of Rhodamine B: Catalyst characterization, performance evaluation, and catalytic mechanism
PublicationIn this work, catalytic activity of natural chalcopyrite (CuFeS2) was improved by thermal activation. The modified chalcopyrite was used as efficient catalyst for degradation of organic dye Rhodamine B (RhB) through advanced oxidation process (AOP). Effects of catalyst dosage, H2O2 concentration, reaction temperature, solution pH, anions, and natural organic matter on the degradation efficiency of RhB were investigated. This study...
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Sposób przelicznia wartości przewodności dźwiękowej C i krytycznego stosunku ciśnień b na współczynnik przepływu m.
PublicationPrzedstawiono algorytm przelicznia wartości przewodności dźwiękowej C i krytycznego stosunku ciśnień b na współczynnik przepływu m. Do rozwiązania tego zadania zaprojektowano również sztuczną sieć neuronową. Oba rozwiązania porównano z wcześniej dostepnymi aolgorytmami.
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ACTA PHYSICA POLONICA B
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Spotkanie TEST B - Do edycji
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Projekt grupowy/badawczy B. Mielewska
e-Learning CoursesProjekt grupowy/badawczy Fizyka medyczna st II - Brygida Mielewska, Marta Marszewska, Jakub Czubek
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Study on Dry Sliding Wear and Friction Behaviour of Al7068/Si3N4/BN Hybrid Composites
PublicationHybrid aluminium metal matrix composites have the potential to replace single reinforced aluminium metal matrix composites due to improved properties. Moreover, tribological performance is critical for these composites, as they have extensive application areas, such as the automotive, aerospace, marine and defence industries. The present work aims to establish the tribological characteristics of Al7068/Si3N4/BN hybrid metal matrix...
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Assessment of Corrosive Behaviour and Microstructure Characterization of Hybrid Friction Stir Welded Martensitic Stainless Steel
PublicationThis study examined the effect of induction heating on the microstructure and corrosion characteristics of hybrid friction stir welded AISI 410 stainless steel. Five joints have been produced with different friction stir welding parameters like welding speed, spindle speed, plunge depth, and induction power. Their microstructures were evaluated using a scanning electron microscope, and chemical composition was examined using...
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Multianalyte Calibration Methods for Potentiometric Integrated Sensors System for Determination of Ions Concentration in a Body Fluids
PublicationIn recent years, integration and miniaturization of ion-selective electrodes (ISEs) have brought many benefits resulting in the possibility of simultaneous determination of the ions concentration in a small sample volume. One of the key problems related to the preparation of integrated sensors systems (ISSs) is a calibration procedure due to the necessity to calibrate each particular sensor separately. The main aim of the research...
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Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
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The effect of boron concentration on the electrical, morphological and optical properties of boron-doped nanocrystalline diamond sheets: Tuning the diamond-on-graphene vertical junction
PublicationIn this paper, the effect of boron doping on the electrical, morphological and structural properties of free-standing nanocrystalline diamond sheets (thickness ~ 1 μm) was investigated. For this purpose, we used diamond films delaminated from a mirror-polished tantalum substrate following a microwave plasma-assisted chemical vapor deposition process, each grown with a different [B]/[C] ratio (up to 20,000 ppm) in the gas phase....
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Iso-Partricin, an Aromatic Analogue of Amphotericin B: How Shining Light on Old Drugs Might Help Create New Ones
PublicationPartricin is a heptaene macrolide antibiotic complex that exhibits exceptional antifungal activity, yet poor selective toxicity, in the pathogen/host system. It consists of two compounds, namely partricin A and B, and both of these molecules incorporate two cis-type bonds within their heptaenic chromophores: 28Z and 30Z. In this contribution, we have proven that partricins are susceptible to a chromophore-straightening photoisomerization...
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Rozstaw rys według PN-EN 1992-1-1:2008 oraz PN-B 03264:2002
PublicationW pracy opisano mechanizm powstawania rys dla osiowo rozciąganego pręta żelbetowego. Na tej podstawie określono maksymalny i minimalny rozstaw rys, konfrontując otrzymane wyniki z procedurami podanymi w normie europejskiej PN-EN 1992-1-1:2008 oraz w normie polskiej PN-B 03264:2002. Przedstawiono praktyczne wnioski do projektowania, wynikajace z przeprowadzonej analizy.
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Thermodynamics and kinetics of amphotericin B self-association in aqueous solution characterized in molecular detail
PublicationAmphotericin B (AmB) is a potent but toxic drug commonly used to treat systemic mycoses. Its efficiency as a therapeutic agent depends on its ability to discriminate between mammalian and fungal cell membranes. The association of AmB monomers in an aqueous environment plays an important role in drug selectivity, as oligomers formed prior to membrane insertion – presumably dimers – are believed to act differently on fungal (ergosterol-rich)...
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The Effect of Sterols on Amphotericin B Self-Aggregation in a Lipid Bilayer as Revealed by Free Energy Simulations
PublicationAmphotericin B (AmB) is an effective but toxic antifungal drug, known to increase the permeability of the cell membrane, presumably by assembling into transmembrane pores in a sterol-dependent manner. The aggregation of AmB molecules in a phospholipid bilayer is, thus, crucial for the drug’s activity. To provide an insight into the molecular nature of this process, here, we report an atomistic molecular dynamics simulation study...
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The Substantial Improvement of Amphotericin B Selective Toxicity Upon Modification of Mycosamine with Bulky Substituents
PublicationAbstract: Background: It is assumed that the unfavorable selective toxicity of an antifungal drug Amphotericin B (AmB) can be improved upon chemical modification of the antibiotic molecule. Objective: The aim of this study was verification of the hypothesis that introduction of bulky substituents at the amino sugar moiety of the antibiotic may result in diminishment of mammalian vitro toxicity of thus prepared AmB derivatives. Methods:...
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Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublicationNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
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NbIr 2 B 2 and TaIr 2 B 2 – New Low Symmetry Noncentrosymmetric Superconductors with Strong Spin–Orbit Coupling
PublicationSuperconductivity was first observed more than a century ago, but the search for new superconducting materials remains a challenge. The Cooper pairs in superconductors are ideal embodiments of quantum entanglement. Thus, novel superconductors can be critical for both learning about electronic systems in condensed matter and for possible application in future quantum technologies. Here two previously unreported materials, NbIr2B2...
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Enhancement of photocatalytic hydrogen evolution with catalysts based on carbonized MOF-5 and g-C3N4
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Drawing Functions and NLP Algorithm Steps for Optimization Problems by using O&G Software.
PublicationPraca opisuje program służący do wizualizacji problemów programowania nieliniowego (funkcja celu, ograniczenia) oraz pracy rozwiązującego je algorytmu. Wizualizacja może być realizowana w przestrzeni dwu- lub trójwymiarowej.
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Database of the minimal sets of Lefschetz periods for Morse-Smale diffeomorphisms of a connected sum of g tori
Open Research DataMorse–Smale diffeomorphisms, structurally stable and having relatively simple dynamics, constitute an important subclass of diffeomorphisms that have been carefully studied during past decades. For a given Morse–Smale diffeomorphism one can consider “Minimal set of Lefschetz periods”, which provides the information about the set of periodic points of...
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Ni2X2 (X=pnictide, chalcogenide, or B) based superconductors
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Genetic Variability of Hepatitis B Virus Isolates in Poland
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Charakterystyka mechanizmów samoorganizującej się, wieloskokowej sieci bezprzewodowej w strefie B systemu netBaltic
PublicationStrefowa struktura systemu netBaltic pozwala na zastosowanie w jego obrębie odmiennych mechanizmów komunikacji sieciowej w zależności od dostępnych w określonym momencie dla danej jednostki możliwości komunikacyjnych. W strefie B systemu przewidziano wykorzystanie samoorganizującej, wieloskokowej sieci o strukturze kratowej, pozwalającej znacząco rozszerzyć zasięg łączności sieciowej poza obszar funkcjonowania lądowych systemów...