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Search results for: CELE SPÓŁKI
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New and Old Genes Associated with Primary and Established Responses to Paclitaxel Treatment in Ovarian Cancer Cell Lines
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Analysis of MDR genes expression and cross-resistance in eight drug resistant ovarian cancer cell lines
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LY294002 and sorafenib as inhibitors of intracellular survival pathways in the elimination of human glioma cells by programmed cell death
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Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts
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In-situ Cu-doped MnCo-spinel coatings for solid oxide cell interconnects processed by electrophoretic deposition
PublicationThe Cu doping of the Mn–Co spinel is obtained “in-situ” by electrophoretic co-deposition of CuO and Mn1.5Co1.5O4 powders and subsequent two-step reactive sintering. Cu-doped Mn1.5Co1.5O4 coatings on Crofer22APU processed by electrophoretic co-deposition method are tested in terms of long term oxidation resistance and area specific resistance tests up to 3600 h. The introduction of Cu in the spinel lead to higher level of densification...
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Przetwarzanie hydroakustycznych i lidarowych danych przestrzennych w celu konstrukcji trójwymiarowych modeli rzeczywistych obiektów
PublicationZautomatyzowana rekonstrukcja kształtu powierzchni reprezentowanych przez chmury punktów jest zagadnieniem badanym od wielu lat, jednak rezultaty osiągane za pomocą istniejących algorytmów odtwarzania modeli są dalekie od satysfakcjonujących, jeżeli wejściowe zbiory punktów cechują się nieregularną strukturą przestrzenną, co jest częstym zjawiskiem w przypadku danych pochodzących z sondowania hydroakustycznego czy skaningu laserowego....
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Nuclear localization of P-glycoprotein is responsible for protection of the nucleus from doxorubicin in the resistant LoVo cell line
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Widma elektronowe kompleksów miedzi(II) z imidazolem w ciele stałym i w roztworze
PublicationZsyntetyzowano szereg związków kompleksowych miedzi(II) z ligandami chlorkowymi i różnymi alkilowymi pochodnymi imidazolu: 4(5) metyloimidazolem, 2-etyloimidazolem, 2-izopropyloimidazolem i 2-etylo-4-metyloimidazolem. Otrzymane głównie kompleksy jednordzeniowe oraz jeden kompleks dwurdzeniowy (z 2-etyloimidazolem). Zbadano widma elektronowe otrzymanych kompleksów w roztworach metanolowych i porównano je z widmami otrzymanymi z...
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Wpływ celu funkcjonowania przedsiębiorstwa oraz jego przynależności sektorowej na wartości wzorcowe wskaźników finansowych
PublicationW artykule została przedstawiona koncepcja rozprawy doktorskiej autora. Zarysowane zostało w nim uzasadnienie podjęcia tematu oraz jego waga, jak również zaprezentowane zostały pytania badawcze, odpowiadające na nie hipotezy oraz dopasowana do nich propozycja struktury rozprawy doktorskiej.
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BADANIA ZNACZNIKOWE W CELU WERYFIKACJI KIERUNKU FILTRACJI POD JAZEM ELEKTROWNI WODNEJ PIŁA-KOSZYCE
PublicationPrzedmiotem opracowania jest wykonanie badań znacznikowych w rejonie jazu piętrzącego EW Koszyce wraz z analizą wyników w celu ustalenia kierunków filtracji wody w pod-łożu budowli. Dodatkowo w ramach niniejszego opracowania przedstawiono analizę piezometryczną dla zapory lewobrzeżnej oraz wykonano badania przy obniżonym poziomie zbiornika powyżej zapory.
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Cabbage Juices and Indoles Modulate the Expression Profile of AhR, ERα, and Nrf2 in Human Breast Cell Lines
PublicationOur previous studies showed the diversified effect of cabbage juices and indoles on the estrogen metabolism key enzymes (CYP1A1, CYP1A2, CYP1B1) in breast epithelial cells differing in ER status, i.e., in tumorigenic—MCF7, MDA-MB-231 and non-tumorigenic—MCF10A cells. The aim of the present study was to further investigate the mechanism of chemopreventive action of cabbage juice and its active components by evaluating their effect...
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Działalność Studenckiego Koła Naukowego CELL przy Katedrze Systemów i Sieci Radiokomunikacyjnych Politechniki Gdańskiej
PublicationZarys działalności i osiągnięć Studenckiego Koła Naukowego CELL zajmującego się popularyzacją zagadnień związanych z telekomunikacją bezprzewodową.
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Fe-modified Mn2CuO4 spinel oxides: coatings based on abundant elements for solid oxide cell interconnects
PublicationThe current state of the art steel interconnect coating materials are based on critical raw material - Co-oxide spinels. Replacing Co-oxide spinels with alternative, abundant materials can reduce the dependence on the critical raw materials. Cobalt-free coatings with the general formula Mn2-xCuFexO4, where x = 0, 0.1, 0.3, were electrophoretically deposited on a ferritic stainless-steel support and evaluated. Prior to deposition,...
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Pharmacomicrobiomics of cell-cycle specific anti-cancer drugs – is it a new perspective for personalized treatment of cancer patients?
PublicationIntestinal bacteria are equipped with an enzyme apparatus that is involved in the active biotrans-formation of xenobiotics, including drugs. Pharmacomicrobiomics, a new area of pharmacology, analyses interactions between bacteria and xenobiotics. However, there is another side to the coin. Pharmacotherapeutic agents can significantly modify the microbiota, which consequently affects their efficacy. In this review, we comprehensively...
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Exploring the Beam Squint Effects on Reflectarray Perfromance: A Comprehensive Analysis of the Specular and Scattered Reflection of the Unit Cell
PublicationIn this article, the phenomena of beam deviation in reflectarray is discussed. The radiation pattern of the unit cell, which plays a vital role in shaping the beam of the reflectarray, is analyzed by considering undesired specular and scattered reflections. These unwanted reflections adversely affect the pattern of the single unit cell, thereby reducing the overall performance of the reflectarray. To conduct our investigations,...
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Novel chalcone-derived pyrazoles as potential therapeutic agents for the treatment of non-small cell lung cancer
PublicationLung cancer is considered to account for approximately one-fifth of all malignant tumor-related deaths worldwide and is therefore one of the most lethal malignancies. Pyrazole scaffold possesses a wide range of biological and pharmacological activities, which play important roles in medicinal chemistry. The present study reports the synthesis and in vitro biological characterization of nine pyrazoles derived from chalcones as potential...
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Application analysis of a hybrid solid oxide fuel cell-gas turbine system for marine power plants
PublicationThe results of theoretical studies of the possibilities of using hybrid solid oxide fuel cell–gas turbine (SOFC-GT) systems for marine power plants are presented. A 500 kW auxiliary marine power plant scheme using stacks of SOFCs in combination with a regenerative gas turbine operating with over-expansion based on our recent patent application is proposed. The results of mathematical modelling showed the opportunity to obtain a...
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Immune escape of B-cell lymphoblastic leukemic cells through a lineage switch to acute myeloid leukemia
PublicationAcute leukemia (AL) with a lineage switch (LS) is associated with poor prognosis. The predisposing factors of LS are unknown, apart from KMT2A rearrangements that have been reported to be associated with LS. Herein, we present two cases and review all 104 published cases to identify risk factors for LS. Most of the patients (75.5%) experienced a switch from the lymphoid phenotype to the myeloid phenotype. Eighteen patients (17.0%)...
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Podzielne szeregowanie zadań dwuprocesorowych na maszynach dedykowanych w celu minimalizacji sumy czasów zakończenia
PublicationW pracy rozważamy deterministyczne szeregowanie zadań dwuprocesorowych na maszynach dedykowanych, które minimalizuje sumę czasów zakończenia, przy czym dopuszcza się możliwość przerwania wykonywania zadania i ponownego wznowienia obsługi z pomijalnie małym kosztem. Wiadomo, że tak postawione zagadnienie jest problemem silnie NP-trudnym. W pracy badamy złożoność obliczeniową problemu, ograniczając liczbę maszyn.
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Modulation of G2 arrest enhances cell death induced by the antitumor 1-nit-roacridine derivative, Nitracrine
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The ability to overcome multidrug resistance of tumor cell lines by novel acridine cytostatics with condensed heterocyclic rings
PublicationZbadano aktywność cytotoksyczną, in vitzo dwóch nowych grup cytostatyków akrydynowych zawierających skondensowane pierścienie heterocykliczne w stosunku do komórek nowotworowych linii wrażliwych i opornych. Otrzymane wyniki potwierdziły naszą wcześniejszą hipotezę o istotnej roli pierścieni hetero-cyklicznych w pokonywaniu krzyżowej oporności wielolekowej.
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Możliwości użycia pojemników z geowłóknin w celu przeciwdziałania podmywaniom brzegów i budowli przybrzeżnych.
PublicationPrzedstawiono doświadczenia niemieckie w zakresie stosowania pojemników z geowłóknin dla rozwiązywania problemów podmywania budowli. Podano ogólne zalecenia w przedmiotowym zakresie.
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Cross-talk between DNA damage and cell survival checkpoints during G2 and mitosis: pharmacological implications
PublicationW pracy wyjaśnialiśmy rolę surwiwiny w ochronie komórek w czasie przejścia między G2 i mitozą, traktowanych związkiem uszkadzającym DNA. Jako model komórkowy wybraliśmy komórki ludzkiej białaczki MOLT-4, które wykazują zwiększoną ekspresję białka surwiwiny i niefunkcjonalnym p53. Ekspozycja tych komórek na melfalan, klasyczny związek uszkadzający DNA, prowadzi do uruchomienia punktu kontrolnego w G2 i zablokowania progresji cyklu...
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Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells
PublicationW przedstawionych badaniach określano mechanizm śmierci komórkowej indukowanej przez imidazoakrydon C-1311 (Symadex) w komórkach HT-29 ludzkiego raka jelita grubego, które wykazywały szczególną wrażliwość na ten związek w eksperymentalnych modelach in vitro i in vivo. Przy stężeniu odpowiadającemu dawce IC99, związek powodował zahamowanie progresji cyklu komórkowej w fazie S po czym następował blok w fazie G2. Po czasach 48-96...
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Jan Cudzik dr inż. arch.
PeopleJan Cudzik (Ph.D. Eng. Arch.) is an assistant professor at the Department of Urban Architecture and Waterside Spaces at the Faculty of Architecture of the Gdańsk University of Technology and the head of the Laboratory of Digital Technologies and Materials of the Future. He is researching kinematic architecture, digital techniques in architectural design, digital fabrication, and forms of artificial intelligence in architecture...
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Piotr Jasiński prof. dr hab. inż.
PeoplePiotr Jasinski obtained MSc in electronics in 1992 from the Gdansk University of Technology (GUT), Poland. Working at GUT, he received PhD in 2000 and DSc in 2009. Between 2001 and 2004 Post Doctoral Fellow at Missouri University of Science and Technology, while between 2008 and 2010 an Assistant Research Professor. Currently is an Associate Professor at Gdansk University of Technology working in the field of electronics, biomedical...
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Anna Danuta Dettlaff dr inż.
PeopleShe received her Master of Science degree in engineering with honours in 2013 at the Gdańsk University of Technology at the Department of Analytical Chemistry. In 2013-2017, she was a PhD student in the field of Chemical Technology at Faculty of Chemistry. Her doctoral dissertation was entitled “Nanocomposites based on conducting polymer and carbon materials for supercapacitor application”. In 2015, she was doing a three-month...
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Clinical significance of CD34, podoplanin and Ki-67 expression in patients with locally advanced squamous cell cervical carcinoma
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Comparison of siRNA-mediated silencing of glycosaminoglycan synthesis genes and enzyme replacement therapy for mucopolysaccharidosis in cell culture studies.
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Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells
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Label-free testing strategy to evaluate packed red blood cell quality before transfusion to leukemia patients
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The Effects of Cellular Membrane Damage on the Long-Term Storage and Adhesion of Probiotic Bacteria in Caco-2 Cell Line
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Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
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Synthesis of isomeric, oxathiolone fuded chalcones and comparison of their activity toward various microorganisms and human cancer cell lines
PublicationIzomeryczne oksationolowe sprzężone chalkony otrzymano w wyniku kondensacji odpowiedniego acetylobenzo[1,3]oksatiolo-2-onu z aldehydem benzoesowym w środowisku kwaśnym. Określono aktywność cytotoksyczną otrzymanych związków wobec komórek linii HeLa, przeciwbakteryjną wobec Micrococcus luteus, Staphylococcus aureus, Salmonella typhimurium, Escherichia coli i Proteus vulgaris, przeciwgrzybową wobec Candida albicans i tuberkulostatyczną...
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Determination of pyridine and adenine nucleotide metabolites in Bacillus subtilis cell extract by sweeping borate complexation capillary electrophoresis
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Bacterial Nanocellulose Fortified with Antimicrobial and Anti-Inflammatory Natural Products from Chelidonium majus Plant Cell Cultures
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Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche
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Contribution of hMTH1 to the Maintenance of 8-Oxoguanine Levels in Lung DNA of Non-Small-Cell Lung Cancer Patients
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Highly crystalline colloidal nickel oxide hole transport layer for low-temperature processable perovskite solar cell
PublicationHighly crystalline NiOX usually requires high annealing temperature (>300 °C) which is incompatible with flexible substrate and might consume high amount of energy. Herein, we demonstrate a facile emulsion process to synthesize highly crystalline, low temperature deposition (<150 °C) and solution processable NiOx nanoparticles (NPs) as a hole transport layer for the perovskite solar cells (PVSCs)....
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Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression
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The Reduced Folate Carrier (SLC19A1) c.80G>A Polymorphism is Associated with Red Cell Folate Concentrations Among Women
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Bacteria Residing at Root Canals Can Induce Cell Proliferation and Alter the Mechanical Properties of Gingival and Cancer Cells
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New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines
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Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
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Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines
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“Cell Migration” Is the Ontology Group Differentially Expressed in Porcine Oocytes Before and After In Vitro Maturation: A Microarray Approach
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Nanoconjugates of graphene oxide derivatives and meso-tetraphenylporphyrin: a new avenue for anticancer photodynamic therapies – Cell-on-a-Chip analysis
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Stability Analysis of the Floating Offshore Wind Turbine Support Structure of Cell Spar Type During its Installation
PublicationThe article presents the results of selected works related to the wider subject of the research conducted at the Faculty of Ocean Engineering and Ship Technology of the Gdansk University of Technology, which concerns design and technology of construction, towing, and settlement on the seabed, or anchoring, of supporting structures for offshore wind farms. As a result of this research, several designs of this type of objects were...
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The impedance of hydrogen oxidation reaction in a proton exchange membrane fuel cell in the presence of carbon monoxide in hydrogen stream
PublicationEvaluation of performance of a proton exchange membrane fuel cell, which is affected by carbon monoxide that pollutes the hydrogen stream, was presented. This influence was studied for carbon monoxide concentration of 125–325 ppb, which are close to values specified in ISO 14687:2019 standard. Performed studies provided crucial information for further development of fuel cell as an energy source for automotive application. Impedance...
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Recent advances on spinel-based protective coatings for solid oxide cell metallic interconnects produced by electrophoretic deposition
PublicationThe application of ceramic protective coatings to the metallic interconnects in solid oxide cells (SOCs) is a viable and effective method to limit interconnect degradation issues. This featured letter provides a critical overview of the main outcomes of current research on the use of the electrophoretic deposition (EPD) technique to produce protective coatings for SOC metallic interconnects, specifically focusing on different approaches...