Search results for: Pharmaceutical cocrystals
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Journal of Pharmaceutical Investigation
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Pharmaceutical Patent Analyst
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SA Pharmaceutical Journal
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Infarma - Pharmaceutical Sciences
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SAUDI PHARMACEUTICAL JOURNAL
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ScienceRise: Pharmaceutical Science
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Egyptian Pharmaceutical Journal
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Selected analytical challenges in the determination of pharmaceuticals in drinking/marine waters and soil/sediment samples
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Determination of pharmaceuticals in fish: method optimization and occurrence in different species from Mediterranean rivers
PublicationThe multi-residue analytical method developed, based on accelerated solvent extraction, gel permeation chromatography purification and UPLC-MS/MS analysis allowed the simultaneous determination of 21 pharmaceuticals. Recoveries obtained for most of the target compounds were higher than 50%. The application of UPLC-MS/MS operating in the MRM mode, with two transitions monitored for each compound, provided good sensitivity and selectivity....
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Determination of solvents residues in vegetable oils and pharmaceuticals by headspace analysis and capillary gas chromatography.
PublicationPrzedstawiono wyniki zastosowania techniki analizy fazy nadpowierzchniowej w połączeniu z kapilarną chromatografią gazową do oznaczania wybranych rozpuszczalników organicznych w próbkach olejów jadalnych i produktów farmaceutycznych. Oznaczane rozpuszczalniki to: benzen, toluen, heksan oraz chlorowcopochodne węglowodorów alifatycznych. Opracowaną procedurę poddano walidacji. Wyznaczono granicę wytrzymalności, oznaczalności, liniowość...
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Environmental aspects of using gas chromatography for determination of pharmaceutical residues in samples characterized by different composition of the matrix
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Microscopic and Spectroscopic Imaging and Thermal Analysis of Acrylates, Silicones and Active Pharmaceutical Ingredients in Adhesive Transdermal Patches
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The application of single drop extraction technique for chromatographic determination of solvent residues in edible oils and pharmaceutical products
PublicationW pracy przedstawiono zalety i wady techniki ekstrakcji do pojedynczej kropli, będącą prostą i tanią alternatywą dla mikroekstrakcji do fazy stacjonarnej. Ponadto opisano dwie analityczne procedury do chromatograficznego oznaczania wybranych rozpuszczalników organicznych (heksanu, benzenu, toluenu oraz trichlorometanu, 1,1,1-trichloroetanu, tetrachlorometanu, trichloroetylenu, tetrachloroetenu)w olejach jadalnych i próbkach farmaceutycznych....
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Microscopic and Spectroscopic Imaging and Thermal Analysis of Acrylates, Silicones and Active Pharmaceutical Ingredients in Adhesive Transdermal Patches
PublicationDermal or transdermal patches are increasingly becoming a noteworthy alternative ascarriers for active pharmaceutical ingredients (APIs), which makes their detailed physicochemical evaluation essential for pharmaceutical development. This paper demonstrates mid-infrared (FTIR) and Raman spectroscopy with complementary microscopic methods (SEM, optical and confocal Raman microscopy) and differential scanning calorimetry...
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Synthesis and properties of CaFe2As2 single crystals
PublicationOpisana została synteza i podstawowe właściwości fizyczne monokryształów CaFe2As2. CaFe2As2 krystalizuje w strukturze ThCr2Si2, stałe sieciowe wynoszą odpowiednio: a = 3.887(4) A and c = 11.758(23) A.
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Liquid Crystals in Analytical Chemistry: A Review
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Journal of Pharmaceutics
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Deep eutectic solvent based method for analysis of Niclosamide in pharmaceutical and wastewater samples – A green analytical chemistry approach
PublicationThe paper presents a simple, but very effective and sensitive spectrophotometric method for trace analysis of Niclosamide based on liquid–liquid microextraction using deep eutectic solvents (DESs) prior to its quantification. Here, different DES systems, such as Choline chloride (ChCl) + Urea, ChCl + Citric acid, ChCl + Ethylene glycol and ChCl + Phenol, were synthesized and evaluated at different molar ratios, selecting ChCl + Phenol...
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Determination of twenty pharmaceutical contaminants in soil using ultrasound-assisted extraction with gas chromatography-mass spectrometric detection
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Treatment innovation using solar/UV In book: The Treatment of Pharmaceutical Wastewater: Innovative Technologies and the Adaptation of Treatment Systems
PublicationSince ancient times, sunlight irradiation has been widely used for water purification. Apart from solar water disinfection techniques, UV irradiation is of particular interest when considering the photodegradation of various classes of emerging pollutants. Pharmaceutically active compounds are one of the largest classes of micropollutants. The main sources of these contaminants in wastewater and aqueous environments are households,...
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Static renewal and continuous-flow calibration of two types of passive samplers for the monitoring of pharmaceuticals in wastewater
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Limitations of Integrative Passive Samplers as a Tool for the Quantification of Pharmaceuticals in the Environment – A Critical Review with the Latest Innovations
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A Holistic Approach to Determining Stereochemistry of Potential Pharmaceuticals by Circular Dichroism with β-Lactams as Test Cases
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Polymer and graphitic carbon nitride based nanohybrids for the photocatalytic degradation of pharmaceuticals in wastewater treatment – A review
PublicationPharmaceuticals, including antibiotics and anti-inflammatory drugs, have been frequently detected in water reservoirs, in concentrations ranging from ng/L to μg/L, owing to their wide use in treatment of human and animal disease. Their uncontrolled use results in their increased release into the environment which is harmful for humans, animals, aquatic life and aquatic system. To remove these pollutants from water bodies, various...
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Spatial distribution of pharmaceuticals in conventional wastewater treatment plant with Sludge Treatment Reed Beds technology
PublicationPharmaceutical residues are an emerging environmental problem. It is strongly confirmed that pharmaceuticals are present in soils and environmental waters (surface, marine and even groundwater), and that wastewater treatment plant (WWTP) effluents are the main source of pharmaceuticals in the watershed. The aim of this studywas to recognize the spatial distribution and seasonal changes of selected pharmaceuticals in conventional WWTP...
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Bisphenols (A, S, and F) affect the basic hormonal activity determined for pharmaceuticals – Study of Saccharomyces cerevisiae
PublicationPharmaceuticals and analogs of bisphenol A (BPA) are increasingly threatening environmental pollutants. In this study, mixtures of selected pharmaceuticals (diclofenac sodium salt, chloramphenicol, oxytetracycline hydrochloride, fluoxetine hydrochloride, estrone, ketoprofen, progesterone, gemfibrozil and androstenedione) were prepared with BPA and its two analogs (namely, bisphenols F and S) at such ratios to reflect environmentally...
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Analytical procedures for quality control of pharmaceuticals in terms of residual solvents content: Challenges and recent developments
PublicationResidual solvents play an important role in the synthesis of drugs and in product formulations. In addition, they pose a serious problem, that is toxicity, as many of them exhibit toxic or environmentally hazardous properties. Therefore, constant monitoring of quality control is needed. In this study, we present an overview of regulatory and general methods described by various pharmacopoeias. Then, the most commonly used methodologies...
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Impact of inorganic ions and pH variations on toxicity and endocrine potential of selected environmentally relevant pharmaceuticals
PublicationAssessment of the impact of pharmaceutical residues on living organisms is a very complex subject. Apart from taking into account the toxicity of individual compounds, environmental factors should also be taken into account. In this paper, attempts were made to assess the impact of coexisting inorganic ions and changes in pH on the toxicity of ten selected pharmaceuticals. Two bioassays were used to measure the estrogenic and androgenic...
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Closing the loop: Upcycling secondary waste materials into nanoarchitectured carbon composites for the electrochemical degradation of pharmaceuticals
PublicationIn this study, we demonstrated the application of electrochemical oxidation as a safer and cleaner technology for minimizing the impact of pharmaceuticals in wastewaters, simultaneously mediated by upcycled secondary waste materials (SWMs)-derived electrodes, to further reduce their environmental impact. The modularity, scalability, ease of operation and reliability make electrochemical oxidation an ideal process for the destruction...
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Interplay between Aryl···Perfluoroaryl and Hydrogen Bonding Interactions in Cocrystals of Pentafluorophenol with Molecules of Trigonal Symmetry
PublicationCocrystals of seven star-shaped triaryl compounds with pentafluorophenol (pfp) were prepared and structurally characterized by the single-crystal X-ray diffraction method. Cocrystallization of pfp with planar (or almost planar) compounds gave six 3:1 molecular complexes with well-defined layered structures. The layers are composed of alternating pfp3 trimers, linked by hydrogen bonding, and triaryl molecules held together in planes...
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Self-assembly of secondary aryl amides in cocrystals with perfluoroaryl coformers: structural analysis and synthon preferences
PublicationCooperation of aryl⋯perfluoroaryl stacking interactions and hydrogen bonds was utilized in the construction of six novel cocrystals of aromatic cis-amides with pentafluorobenzoic acid (pfba) and pentafluorophenol (pfp). They were obtained by crystallization from solution and structurally characterized. In four instances, the components form heterotetrameric motifs, in which amide:amide homodimer interacts symmetrically on two sides...
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Pharmaceuticals Policy and Law
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Cations of amino acid alkyl esters conjugated with an anion from the group of NSAIDs – As tunable pharmaceutical active ionic liquids
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Phototransformation of three selected pharmaceuticals, naproxen, 17α-Ethinylestradiol and tetracycline in water: Identification of photoproducts and transformation pathways
PublicationTransformation products (TPs) may be formed during various processes, however, it was proved that one of the main mechanisms responsible for degradation of pharmaceuticals in natural waters is photolysis. Three compounds were selected, tetracycline (TC), 17-α-ethinylestradiol (EE2) and naproxen (NAP), for degradation experiments which were performed using a xenon lamp emitting light with a spectrum closely approximating that of...
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Application of the PASSIL technique for the passive sampling of exemplary polar contaminants (pharmaceuticals and phenolic derivatives) from water
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Novel composite of Zn/Ti-layered double hydroxide coupled with MXene for the efficient photocatalytic degradation of pharmaceuticals
PublicationIn the present study, a hybrid photocatalyst of Zn/Ti layered double hydroxide (LDH) coupled with MXene – Ti3C2 was synthesized for the first time and applied in photocatalytic degradation of acetaminophen and ibuprofen, two commonly present in the natural environment and prone to accumulate in the aquatic ecosystem pharmaceuticals. The effect of MXene content (0.5 wt%, 2.5 wt%, and 5 wt%) on the photocatalytic activity of LDH/MXene...
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Acta Pharmaceutica Hungarica
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Acta Pharmaceutica Sciencia
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Calculation of vibrational spectra for cyanobiphenyl liquid crystals
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Surface studies of twinned of YBa2Cu3O7−δ crystals
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Growth and characterization of PrBa2Cu3O7-δ single crystals
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Liquid crystals thermography for technical and biomedical application
PublicationW artykule opisano termografię ciekłokrystaliczną jako technikę wykorzystu-jącą termochromatyczne ciekłe kryształy do badań technicznych i biomedycz-nych. W szczególności dotyczy to badań wymiany ciepła i masy, chorób skór-nych i podobnych. Praca zawiera ilustracje z badań przeprowadzonych przezautorów.
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Prospects in Pharmaceutical Sciences
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Analysis of chiral pharmaceutical residues in influent and effluent samples at racemic and enantiomeric level using liquid chromatography-tandem mass spectrometry
PublicationIn this work, two different chromatographic methods for seasonal monitoring of pharmaceutical residue in wastewater samples were developed. In the case of enantiomeric separation of selected compounds, LC-MS technique combining with vancomycin based chiral stationary phase was used. The performance of chiral analysis enabled to monitor the pharmaceutical contamination at the enantiomeric level. The d-SPE procedure was developed...
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Investigating COVID-19 active pharmaceutical ingredients (APIs) degradation using Peroxydisulfate/FeMnOx binary metal oxide/Ultrasound System
PublicationDegradation of Favipiravir using a hybrid system of peroxydisulfate, FeMnOx binary metal oxide, and ultrasound irradiation was studied. A novel catalyst was synthesized with deep eutectic solvent (DES). The effects of DES type on catalytic performance was evaluated and the catalysts were characterized using XRD, SEM, BET, XPS, and EDS. DES-based catalysts exhibited higher efficiency due to structure change, surface area enhancement...
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Pharmaceuticals and another groups of emerging contaminants: Occurrence and sources in Admiralty Bay (King George Island, Maritime Antarctica)
PublicationEveryday live activities may introduce a wide range of chemicals into wastewater systems. In this study presence of selected types of pharmaceuticals from cardiovascular system group, nervous and muscolo-skeleton system group, antimicrobial agents, genitourinary and sex hormones were tested in the wastewater from H. Arctowski Antarctic station. Moreover, the receiver of discharged wastewater (Admiralty Bay) were also studied. Considering...
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Impact of humic acids, temperature and stirring on passive extraction of pharmaceuticals from water by trihexyl(tetradecyl)phosphonium dicyanamide
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Evaluation of the Possibility of Using Hydroponic Cultivations for the Removal of Pharmaceuticals and Endocrine Disrupting Compounds in Municipal Sewage Treatment Plants
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Matrix effects and recovery calculations in analyses of pharmaceuticals based on the determination of β-blockers and β-agonists in environmental samples
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Development of headspace solid-phase microextraction-gas chromatography method for the determination of solvent residues in edible oils and pharmaceuticals
PublicationW pracy przedstawiono wyniki opracowania procedury oznaczania pozostałości rozpuszczalników organicznych w olejach jadalnych z wykorzystaniem techniki HS-SPME na etapie izolacji i wzbogacania analitów. Przedstawiono proces optymalizacji etapu izolacji i rozdzielenia związków. Dla każdego z analitów wyznaczono parametry walidacyjne charakteryzujące procedurę tj. granice wykrywalności, granicę oznaczalności, liniowość, zakres pomiarowy,...
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Analysis of multi-class pharmaceuticals in fish tissues by ultra-high-performance liquid chromatography tandem mass spectrometry
PublicationA new sensitive method based on pressurized liquid extraction (PLE) and purification by gel permeation chromatography (GPC) prior to ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS) was developed for the determination in fish homogenate, liver and muscle of twenty pharmaceuticals compounds and metabolites from seven commonly used therapeutic families. An extensive matrix effect evaluation...
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Brazilian Journal of Pharmaceutical Sciences
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Future Journal of Pharmaceutical Sciences
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International Journal of Pharmaceutical Investigation
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International Journal of Pharmaceutical Applications.
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EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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British Journal of Pharmaceutical Research
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Journal of Pharmaceutical and Scientific Innovation
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World Journal of Pharmaceutical Research
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Asian Journal of Pharmaceutical Sciences
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Journal of Pharmaceutical Negative Results
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International Journal of Pharmaceutical Chemistry
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DARU-Journal of Pharmaceutical Sciences
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Fabad Journal of Pharmaceutical Sciences
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Thai Journal of Pharmaceutical Sciences
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Journal of Applied Pharmaceutical Science
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INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
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Journal of China Pharmaceutical University
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Journal of International Pharmaceutical Research
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Journal of Chinese Pharmaceutical Sciences
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Iranian Journal of Pharmaceutical Sciences
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Journal of Pharmaceutical Research International
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Azerbaijan Pharmaceutical and Pharmacotherapy Journal
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Chinese Journal of Pharmaceutical Biotechnology
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Journal of Reports in Pharmaceutical Sciences
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Journal of Pharmaceutical Policy and Practice
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EPC - European Pharmaceutical Contractor
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Turkish Journal of Pharmaceutical Sciences
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Journal of Pharmaceutical Sciences and Research
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International Journal of Pharmaceutical Compounding
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Jordan Journal of Pharmaceutical Sciences
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AMERICAN JOURNAL OF PHARMACEUTICAL EDUCATION
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Pharmaceutical Technology in Hospital Pharmacy
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Iraqi Journal of Pharmaceutical Sciences
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Pakistan Journal of Pharmaceutical Sciences
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JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
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European Pharmaceutical Law Review
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Iranian Journal of Pharmaceutical Research
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Advances in Pharmacological and Pharmaceutical Sciences
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TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
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Development of factors and measurement of personnel risk in the marketing services of four Polish pharmaceutical companies
Open Research DataThis text contains the presentation and analysis of research results in relation to four companies (A, B, C, D), according to the adopted case study method.Further considerations should be preceded by the assumption that personal risk factors often affect the level of this risk in various directions, so their final impact is the result of the shaping...
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PHARMACEUTICAL RESEARCH
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Infrared Stimulated Luminescence of Ce3+ Doped YAG Crystals
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LITHIUM FLUORIDE CRYSTALS AS FLUORESCENT NUCLEAR TRACK DETECTORS
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Layer contraction of smectic liquid crystals and the compensation model
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Manganese Distribution in CdMnTeSe Crystals. EXAFS Data Analysis
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The first order phase transition and superconductivity in BaNi2As2single crystals
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Structural properties of superconducting PrBa2Cu3O7−δ single crystals
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Thermochromic liquid crystals applied for heat transfer research
PublicationAutorzy opisali własne wieloletnie doświadczenia z badań wymiany ciepła, w których wykorzystali termochromatyczne ciekłe kryształy. Obejmowały one badania przepływów w kanałach o różnorakiej konfiguracji, badania w przestrzeniach zamkniętych oraz podczas zmiany stanu skupienia badanego płynu.
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The use of thermochromic liquid crystals in heat transfer research
PublicationW ostatnich latach ciekłe kryształy zostały z powodzeniem zastosowane do wizualizacji pola temperatury w stanach ustalonych i przejściowych na różnych powierzchniach. Analiza otrzymanych obrazów początkowo była skomplikowana, ale dzięki zastosowaniu obróbki komputerowej pomiary stały się o wiele dokładniejsze i szybsze. W opracowaniu przedstawiono przegląd badań, w których zastosowano automatyczną technikę analizy obrazów, a prowadzone...