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Wyniki wyszukiwania dla: male reproductive tract
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Serum bisphenol A concentrations correlate with serum testosterone levels in women with polycystic ovary syndrome
PublikacjaThe aim of this study was to determine serum bisphenol A (BPA) concentrations using high performance liquid chromatography with tandem mass spectrometry (HPLC–MS/MS) in women with polycystic ovary syndrome (PCOS) (n=106, age range 18–40 yrs) and to evaluate its potential impact on their hormonal and metabolic profile. The control group consisted of age- and BMI-matched 80 eumenorrheic women with no clinical or biochemical hyperandrogenism....
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Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome
PublikacjaBisphenols (BPs) have become a chemical group of special interest due to their ability to interfere with the endocrine system and their ubiquitous presence in the environment. As some of them possess mild estrogenic and anti-androgenic effects, they might be associated with the diagnosis of polycystic ovary syndrome (PCOS). Acting on multiple tissues, BPs exposure may lead to metabolic derangements characteristic for metabolic...
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A system for singing training
PublikacjaThe system proposed is aimed at the vocal students and persons who want to improve emission of their voices. The goal is not to substituite a singing teacher but to provide a tool for automatic teaching of voice emission basics. In this way singers can develop their vocal skills and improve them. By a visual feedback a student can control and modify vocal tract maximas (resonances) of a chosen vowel to match the resonances of the...
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The impact of gender wage gap on sectoral economic growth – cross-country approach
PublikacjaWe propose an empirical analysis of testing the relationship between gender wage gap and economic growth. The study takes into account 12 manufacturing sectors in 18 OECD countries for the period between 1970 and 2005.We use industrial statistics (EU KLEMS, 2008) on female and male wages that distinguish between wages paid to different groups of workers classified according to skill level: high, medium and low. We estimate augmented...
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Tożsamość przedsiębiorcza a stereotypy płci w firmach rodzinnych
PublikacjaThis article analyses various aspects of women’s experiences in overcoming gender stereotypes that they encounter in family businesses. Historically, entrepreneurship was regarded as a male domain in the literature and entrepreneurs have traditionally been described with typical and stereotypical masculine features. When woman engages in economic activities, she must face the potential incoherence...
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Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse
PublikacjaThe MRL/MpJ mouse is an inbred laboratory strain of Mus musculus, known to exhibit enhanced autoimmunity, increased wound healing, and increased regeneration properties. We report the full-length mitochondrial DNA (mtDNA) sequence of the MRL mouse (Accession # EU450583), and characterize the discovery of two naturally occurring heteroplasmic sites. The first is a T3900C substitution in the TpsiCloop of the tRNA methionine gene...
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Polymer biodegradable coatings as active substance release systems for urological applications
PublikacjaCatheter-associated urinary tract infections are the result of catheterization of the bladder. The risk of infection is directly proportional to the length of the bladder catheterization. Bacteria cells have the ability to adhere and create the biofilm on the surface of catheter materials. Bacteria’s biofilm is an extremely beneficial environment of existence for microorganisms. Microorganisms that are an integral part of the biofilm...
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Gender as a Moderator of the Double Bias of Mistakes – Knowledge Culture and Knowledge Sharing Effects
PublikacjaThere is no learning without mistakes. The essence of the double bias of mistakes is the contradiction between an often-declared positive attitude towards learning from mistakes, and negative experiences when mistakes occur. Financial and personal consequences, shame, and blame force desperate employees to hide their mistakes. These adverse outcomes are doubled in organizations by the common belief that managers never make mistakes,...
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Influence of the shoe type on the ground reaction forces
PublikacjaThe aim of this work was to estimate a relationship between the type of the footwear and ground reactions. Differences in medio-lateral, anterior-posterior and vertical reactions are compared for different shoe-types for male and female volunteers. Each of the participants gait was recorded in case of different shoes and without them, also stabilograms were analyzed. Results revealed differences in ground reaction forces for different...
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Urine headspace analysis in medical diagnostics
PublikacjaThe analysis of the volatile organic compounds in the bodily fluids such as urine may provide useful information on the patients’ general health. The potential application of urine headspace analysis could facilitate the diagnostics of various diseases such as metabolic disorders, urinary tract diseases and gastrointestinal conditions. Described in this paper are the currently available techniques of urine sample analysis as well...
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Gender differences in entrepreneurship myths
PublikacjaThe article presents the research results related to the most popular entrepreneurship myths in a group of business students. The author focused on gender differences in myth intensity, credibility and importance based on subject literature. The statistic analysis does not confirm any significant differences between male and female groups in case of the majority of myths, however women’s entrepreneurial intentions proved to be...
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Evaluation of a new freezing protocol containing 20% dimethyl sulphoxide concentration to cryopreserve human ovarian tissue
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Expression of genes associated with BMP signaling pathway in porcine oocytes before and after IVM – a microarray approach
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Escherichia coli Strains with Virulent Factors Typical for Uropathogens were Isolated from Sinuses from Patients with Chronic Rhinosinusitis—Case Report
PublikacjaEscherichia coli were isolated from three patients with chronic rhinosinusitis (CRS) by intraoperative sinus tissue biopsy. Taking into account the unusual replicative niche and previous treatment failures, it was decided to focus on the virulence and drug resistance of these bacteria. The strains turned out to be multi-sensitive, but the rich virulence factors profile of bacteria typical for phylogenetic group B2 deserved attention....
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Application of human bile salts for in vitro digestion models
PublikacjaIn this study, experimental in vitro models simulating the environment of the human gastrointestinal tract were used to assess the impact of physiological surfactants, such as bile salts, on the kinetics of digestion. Bile salts are biosurfactants synthesised in the liver and secreted together with bile into the small intestine. There are many reports on the role of bile salts in lipolysis, but the knowledge of their influence...
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The New Klebsiella pneumoniae ST152 Variants with Hypermucoviscous Phenotype Isolated from Renal Transplant Recipients with Asymptomatic Bacteriuria-Genetic Characteristics by WGS.
PublikacjaKlebsiella pneumoniae (Kp) is one of the most important etiological factors of urinary tract infections in renal transplant (RTx) recipients. We described the antimicrobial susceptibility phenotypes and genomic features of two hypermucoviscous (HM) Kp isolates recovered from RTx recipients with asymptomatic bacteriuria (ABU). Using whole genome sequencing (WGS) data, we showed that the strains belong to the ST152 lineage with the...
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Instrumental techniques used in the analysis of exhaled air
PublikacjaExhaled air composition changes depending on the health status of the patient, making it possible to use breath analysis for diagnosis and monitoring purposes. Despite the fact that it is not yet used in every day medical practice, it potential application could facilitate the diagnostics of various diseases such as metabolic disorders, respiratory tract and gastrointestinal diseases. Described in this paper are different application...
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Comparison of Redox Properties of Flavonoid Aglycones and Corresponding Glycosides and Their Mixtures in the Cellular Model
PublikacjaFlavonoids are polyphenolic compounds commonly found in plants. As dietary components, they have been shown to exhibit numerous pro-health properties that are believed to be associated with their antioxidant effects. In this study, the antioxidant activity of four flavonoid compounds was determined by cellular antioxidant activity assay using HT29 cells as a model of the alimentary tract. The strongest impact on cellular redox...
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Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models?
PublikacjaDuring the last decade, there has been a growing interest in understanding food's digestive fate in order to strengthen the possible effects of food on human health. Ideally, food digestion should be studied in vivo on humans but this is not always ethically and financially possible. Therefore, simple in vitro digestion models mimicking the gastrointestinal tract have been proposed as alternatives to in vivo experiments. Thus,...
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An Empirical Study on the Impact of Gender on Mobile Applications Usability
PublikacjaIn the area of broadband wireless Internet, mobile applications have already replaced their desktop equivalents and are recognized as valuable tools for any size of businesses and for private use. With the emergence of millions of apps, the quality of their interaction with the user remains an open question for software vendors. While female and male requirements and preferences are not always similar, to the best of our knowledge,...
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Entrepreneurial education and attitudes among young generations in a gender perspective: the case of Polish educational system
PublikacjaThis paper is an attempt to analyze the impact of entrepreneurship education on entrepreneurial attitudes and intentions of young people: male and female students of Polish high schools and universities. The author makes an effort to verify the impact of the exposure to the business education and entrepreneurs on the decision to start-up. Special emphasis will be placed on the gender differences when discussing a respective factors’...
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Entrepreneurial Education and Attitude among Young Generations in a Gender perspective: the Case of Polish Education System
PublikacjaThis article is an attempt to analyze the impact of entrepreneurship education on entrepreneurial attitudes and intentions of young people: male and female students of Polish high schools and universities. The author makes an effort to verify the impact of the exposure to the business education and entrepreneurs on the decision to start-up. Special emphasis will be placed on the gender differences when discussing a respective factors’...
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Toxoplasma gondii Recombinant Antigens in the Serodiagnosis of Toxoplasmosis in Domestic and Farm Animals
PublikacjaToxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, and is a parasitic disease that occurs in all warm-blooded animals, including humans. Toxoplasmosis is one of the most common parasitic diseases of animals and results in reproductive losses. Toxoplasmosis in humans is usually caused by eating raw or undercooked meat or consuming dairy products containing the parasite. Diagnosis of toxoplasmosis is currently...
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Platform Supporting the Esophageal Impedance Analysis
PublikacjaThe esophageal pH-impedance examination is one of the most popular diagnostic methods for identifying the upper gastrointestinal tract’s diseases. Inconclusive test evaluation criteria makes it difficult to state the definite diagnosis. In this paper, the computer platform supporting the research and teaching process in the area of pH-impedance analysis is presented. Users, having a variety of mathematical and statistical methods...
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Biofilm bakteryjny uropatogennych szczepów E. coli Dr+ jako czynnik indukujący przewlekłość zakażeń dróg moczowych ograniczający ich leczenie
PublikacjaZakażenia dróg moczowych (ZUM) stanowią jedne z najczęściej występujących infekcji bakteryjnych, dotykających każdego roku miliony osób na świecie. Problematyka tych zakażeń wynika z ich przewlekłości i nawrotów, pomimo stosowania terapii antybiotykowej oraz ciągle wzrastającej lekooporności uropatogenów je wywołujących. Dominującym czynnikiem etiologicznym ZUM są uropatogenne szczepy E. coli (UPECs), wykazujące zdolność do adhezji,...
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Characterisation of Escherichia coli isolates from the blood of haematological adult patients with bacteraemia: translocation from gut to blood requires the cooperation of multiple virulence factors
PublikacjaThe aim of the study was to investigate whether there are unique pathotypes of Escherichia coli capable of transmission from the gastrointestinal tract to the vascular bed. The study included E. coli strains isolated from clinical materials collected from 115 patients suffering from haematologic malignancies diagnosed with bacteraemia. The genotyping techniques established that 89 E. coli isolates from the blood had the same genotype...
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Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
PublikacjaBecause of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DEAH-box helicase, which participates in gene expression and replication by recognizing and unwinding parallel G4s. Here, we studied the molecular basis for the high affinity and specificity of DHX36 for parallel-type...
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Static in vitro digestion model adapted to the general older adult population: an INFOGEST international consensus
PublikacjaUnderstanding the mechanisms of food digestion is of paramount importance to determine the effect foods have on human health. Significant knowledge on the fate of food during digestion has been generated in healthy adults due to the development of physiologically-relevant in vitro digestion models. However, it appears that the performance of the oro-gastrointestinal tract is affected by ageing and that a model simulating the digestive...
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The analysis of human leukocyte antigen‐G level in patients with endometrial cancer by Western blot technique
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The role of environmental optimization for storing bulls’ sperm cells
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Asymptomatic Bacteriuria in Kidney Transplant Recipients—A Narrative Review
PublikacjaUrinary tract infections (UTIs) are the most prevalent complications in kidney transplant (KTx) recipients. The most frequent finding in this group of patients is asymptomatic bacteriuria (ASB). Here, we provide an overview of the available evidence regarding ASB in KTx recipients, including its etiopathology, clinical impact and management. There is a growing body of evidence from clinical trials that screening for and treating...
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Improving Objective Speech Quality Indicators in Noise Conditions
PublikacjaThis work aims at modifying speech signal samples and test them with objective speech quality indicators after mixing the original signals with noise or with an interfering signal. Modifications that are applied to the signal are related to the Lombard speech characteristics, i.e., pitch shifting, utterance duration changes, vocal tract scaling, manipulation of formants. A set of words and sentences in Polish, recorded in silence,...
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Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311 : Highly Selective Substrates for UGT1A10
Publikacja5-Diethylaminoethylamino-8-hydroxyimidazoacridinone, C-1311 (NSC-645809), is an antitumor agent shown to be effective against breast cancer in phase II clinical trials. A similar compound, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone, C-1305, shows high activity against experimental tumors and is expected to have even more beneficial pharmacological properties than C-1311. Previously published studies showed that these...
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Occurrences, sources, and transport of organochlorine pesticides in the aquatic environment of Antarctica
PublikacjaWe review information on the concentration levels of organochlorine pesticides in the abiotic aquatic environment (in seawater, sea ice, surface freshwater, snow, firn, and glacial ice) and the organisms inhabiting those, in Antarctica. Particular attention is given to the environmental fate of these pollutants, which modifies their impact on the organisms living in the Antarctic. OCPs have been delivered to the Antarctic environment...
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A subset of two adherence systems, acute pro-inflammatory pap genes and invasion coding dra, fim, or sfa, increases the risk of Escherichia coli translocation to the bloodstream
PublikacjaAn analysis of the phylogenetic distribution and virulence genes of Escherichia coli isolates which predispose this bacteria to translocate from the urinary tract to the bloodstream is presented. One-dimensional analysis indicated that the occurrence of P fimbriae and α-hemolysin coding genes is more frequent among the E. coli which cause bacteremia. However, a two-dimensional analysis revealed that a combination of genes coding...
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Proteolysis of whey protein isolates in nanoemulsion systems: impact of nanoemulsification and additional synthetic emulsifiers
PublikacjaNanoemulsions are currently of interest in the functional food sector because their small droplet size (100–500 nm) provides a number of potential advantages over conventional emulsions. This study concerned the behavior of nanoemulsions stabilized with whey proteins and two synthetic emulsifiers (Tween 80 and Croduret), and exposed to conditions simulating the human upper gastrointestinal tract. In particular, the effect of synthetic...
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Breastfeeding as a regulating factor of the development of the intestinal microbiome in the early stages of life
PublikacjaSince the first bacterial inhabitants of the human gastrointestinal tract were identified, a lot of research into the study of the human microbiome and its effects on health has been conducted. Currently, it is accepted that humans have a symbiotic relationship with the gut microbiome, though the specifics of this relationship are not well understood. The microbiome of neonates constantly changes and appears to influence many facets...
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Health-Promoting Effects of Ethylene-Treated Kiwifruit ‘Hayward’ from Conventional and Organic Crops in Rats Fed an Atherogenic Diet
PublikacjaKiwifruit is a subtropical fruit that is very popular among consumers. Kiwifruit ‘Hayward’ (Actinidia deliciosa C.F. Liang et A.R. Ferguson) is an important source of bioactive compounds and possesses high antioxidant capacity, but its value can be changed during ripening. The aim of this study was to compare the levels of total polyphenols (TP), ascorbic acid (AA), and total antioxidant capacities (TACs) of ethylene-treated and...
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Transformational Leadership and Acceptance of Mistakes as a Source of Learning: Poland-USA Cross-Country Study
PublikacjaThis study explores the influence of transformational leadership on internal innovativeness mediated by mistakes acceptance, including country and industry as factors to be considered and gender and risk-taking attitude as moderators. General findings, primarily based on the US samples (healthcare, construction, and IT industry), confirmed that transformational leadership and internal innovativeness are mediated by mistakes acceptance...
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Towards hand grip force assessment by using EMG estimators
PublikacjaThe purpose of this study was to propose a method to assess individual regression (calibration) curves to establish a relationship between an isometric grip force and surface electromyography (EMG) estimator. In this study 18 healthy volunteers (12 male (23.0 ± 2.0 years) and 6 female (23.2 ± 0.7 years)) had been examined. Ten EMG estimators (mean absolute value, root mean square, entropy, energy, turns per second, mean of zero...
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Analogue CMOS ASICs in Image Processing Systems
PublikacjaIn this paper a survey of analog application specific integrated circuits (ASICs) for low-level image processing, called vision chips, is presented. Due to the specific requirements, the vision chips are designed using different architectures best suited to their functions. The main types of the vision chip architectures and their properties are presented and characterized on selected examples of prototype integrated circuits (ICs)...
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Approaches to Static Digestion Models
PublikacjaIt is not possible to look in detail at the wide range of static digestion methods that have been used to date. However, this section looks at some of the general approaches that have been used to look at the digestion of various nutrients and bioactives. I have focussed on the two main nutrients that undergo digestion in the upper GI tract, namely protein and lipid. In the case of protein, the research has largely been driven...
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New Analogues of Mycophenolic Acid
PublikacjaMycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. It is a non-competitive and reversible inhibitor of dehydrogenase inosine-5'-monophosphate (IMPDH). This compound belongs to the immunosuppressive drugs used for the prevention of both acute and chronic transplant rejection. Until now, two derivatives of MPA have been used clinically: mycophenolate mofetil (MMF,...
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Assessment of cytotoxic and endocrine potential of selected xenobiotics commonly present in food products
PublikacjaMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds (EDC). A vast number of chemical substances is considered to belong to the this group, including substances which occur naturally in the environment, such as mycotoxins and phytoestrogens, and substances...
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Ultrasound assisted solvent extraction of porous membrane-packed samples followed by liquid chromatography-tandem mass spectrometry for determination of BADGE, BFDGE and their derivatives in packed vegetables
PublikacjaThe problem of the presence of trace organic pollutants in food is of growing importance due to increasing awareness about their impact on newborns, infants and adults of reproductive age. Despite the fact that packaged food products offer many advantages, packaging can be a source of contamination for stored food. Thus, monitoring such pollution in food is of high importance. In this work, a novel methodology based on the solvent...
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Overcoming gender bias in the digital economy. Empirical evidence for European countries
PublikacjaThis study aims to contribute to understanding the gender biases that emerge in the digital technology-related field. More specifically we concentrate on examining whether gender gaps are diminishing or are persistent in terms of women’s enrollment in technology-related programs at the tertiary level of education and for female STEM graduates. Next, this evidence is confronted with gender biases in the labor market regarding changing...
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Extraction and Analysis of Bisphenols and Their Derivatives in Infant and Toddler Ready-to-feed Meals by Ultrasound-assisted Membrane Extraction Followed by LC MS/MS
PublikacjaThis research developed an ultrasound-assisted membrane extraction coupled with liquid chromatography-tandem mass spectrometry method for the determination of nineteen bisphenols and their derivatives in infant and toddler ready-to-feed meals. The calibration curves for all analytes were linear in the tested range, and the limit of detection and limit of quantitation were in the range 0.27 to 0.79 ng/g and 0.80 to 2.4 ng/g, respectively....
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Treatment of Odontogenic Maxillary Sinusitis with the Use of Growth Factors in Advanced Platelet-Rich Fibrin for Immediate Closure of Oro-Antral Communication: A Case Report
PublikacjaChronic odontogenic maxillary sinusitis (COMS), a prolonged inflammation of the maxillary sinus lasting over 12 weeks, is often a result of periapical lesions, marginal periodontitis, and complications like oro-antral communication (OAC) and fistula (OAF). OAC, commonly emerging post-teeth extraction in the lateral maxilla, lacks documented treatments using advanced platelet-rich fibrin (A-PRF). This study evaluates A-PRF’s efficacy...
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Sleep Apnea Detection by Means of Analyzing Electrocardiographic Signal
PublikacjaObstructive sleep apnea (OSA) is a condition of cyclic, periodic ob-struction (stenosis) of the upper respiratory tract. OSA could be associated with serious cardiovascular problems, such as hypertension, arrhythmias, hearth failure or peripheral vascular disease. Understanding the way of connection between OSA and cardiovascular diseases is important to choose proper treatment strategy. In this paper, we present a method for integrated...
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The convergence of gender wage differences - myth or fact - multi country multi sector analysis
PublikacjaThe Becker’s theory of discrimination predicts that in the long run the gender wage differences should disappear. In our empirical analysis we verify the testable implications of this mode considering the hypothesis of gender wage gap convergence. The study takes into account 31 sectors in 13 European countries for the period between 1970 and 2005. We distinguish between wages paid to different groups of workers classified according...