Wyniki wyszukiwania dla: MAJOR DEPRESSIVE DISORDER
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The influence of ILs on TiO2 microspheres activity towards 5-FU removal under artificial sunlight irradiation
PublikacjaIn this work, the effect of various ionic liquids (ILs), namely, choline chloride [Chol][Cl], hexadecylpyridynium chloride [HDPy][Cl], and tributylmethylammonium chloride [TBMA][Cl], on the morphology, surface compo-sition in relation to photocatalytic oxidation of 5-fluorouracil (5-FU) and phenol in the presence of TiO2 pho-tocatalysts under artificial sunlight conditions was investigated. The highest photoactivity towards cytostatic...
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Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding
PublikacjaWe have reported that the hsp70 chaperone DnaK from Escherichia coli might assist protein folding by catalyzing the cis/trans isomerization of secondary amide peptide bonds in unfolded or partially folded proteins. In this study a series of fatty acylated benzamido inhibitors of the cis/trans isomerase activity of DnaK was developed and tested for antibacterial effects in E. coli MC4100 cells. Nα-[Tetradecanoyl-(4-aminomethylbenzoyl)]-l-asparagine...
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Individual entrepreneurial orientation: comparison of business and STEM students
PublikacjaAbstract Purpose – The purpose of this study is to determine whether there are differences in Individual Entrepreneurial Orientation (IEO) between students who are doing their major in business studies and the ones whose areas of study are science, technology, engineering, and mathematics (STEM). Design/methodology/approach – The current research investigates which factors and components contribute to EO orientation development...
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The comparison of cytotoxic and genotoxic activities of glucosinolates, isothiocyanates, and indoles
PublikacjaChemopreventive properties of Brassica vegetables are attributed mainly to their characteristic compounds—glucosinolates (GLs) and their main hydrolysis products—isothiocyanates (ITCs) and indoles. In this study, we compared antiproliferative activity (MTT test in HT29 cells) and genotoxic effects (comet assay in HT29 cells and restriction analysis in a cell-free system) of three GLs (sinigrin (SIN), glucotropaeolin (GTL), and...
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The protocol for using elastic wall model in modeling blood flow within human artery
PublikacjaMedical diagnostic tools will play a major role in the future for an effective patient treatment and reduction their mortality, related to the cardiovascular system diseases (CVDs). There is an urgent need for developing diagnostic procedure to be robust, reliable, accurate and efficient, in the framework of a paradigm shift. Application of numerical techniques is seen as a perspective tool for such purpose. Nevertheless, existing...
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Design and synthesis of TiO2/Ti3C2 composites for highly efficient photocatalytic removal of acetaminophen: The relationships between synthesis parameters, physicochemical properties, and photocatalytic activity
PublikacjaIn this study, we report the potential of TiO2/Ti3C2 composite fabricated by oxidation of MXene for degradation of persistent organic pollutants. The effect of the synthesis conditions (time, temperature, and reaction environment) on the morphology, physicochemical properties, and photocatalytic activity was investigated. It was found that acetaminophen degradation was positively correlated with TiO2 content in the composite structure. Furthermore,...
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Expedited Globalized Antenna Optimization by Principal Components and Variable-Fidelity EM Simulations: Application to Microstrip Antenna Design
PublikacjaParameter optimization, also referred to as design closure, is imperative in the development of modern antennas. Theoretical considerations along with rough dimension adjustment through supervised parameter sweeping can only yield initial designs that need to be further tuned to boost the antenna performance. The major challenges include handling of multi-dimensional parameter spaces while accounting for several objectives and...
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Robust Parameter Tuning of Antenna Structures by Means of Design Specification Adaptation
PublikacjaParameter tuning through numerical optimization has become instrumental in the design of high-performance antenna systems. Yet, practical optimization faces several major challenges, including high cost of massive evaluations of antenna characteristics, normally involving full-wave electromagnetic (EM) analysis, large numbers of adjustable variables, the shortage of reasonable initial solutions in the case of topologically complex...
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Expedited antenna optimization with numerical derivatives and gradient change tracking
PublikacjaDesign automation has been playing an increasing role in the development of novel antenna structures for various applications. One of its aspects is electromagnetic (EM)-driven design closure, typically applied upon establishing the antenna topology, and aiming at adjustment of geometry parameters to boost the performance figures as much as possible. Parametric optimization is often realized using local methods given usually reasonable...
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Moduł Warsztaty - narzędzie w procesie edukacji na uczelni wyższej
PublikacjaObecnie istnieje bardzo szeroka gama narzędzi informatycznych, które wspierają proces edukacji przy wykorzystaniu internetu na uczelniach wyższych. Wśród nieodpłatnych narzędzi powszechnie znana jest platforma Moodle. W artykule zaprezentowano jeden z jej modułów – Warsztaty. Przedstawiono jego funkcjonalność. Opisano jego zalety i wady w nauczaniu łączącym techniki online i tradycyjne na uczelni wyższej (blended-learning). W artykule...
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The impact of sediment, fresh and marine water on the concentration of chemical elements in water of the ice-covered lagoon
PublikacjaThe common use of chemical elements by man has been contributing to their extraction for centuries. As a consequence, they have been directly or indirectly introduced into the biogeochemical cycle. In the framework of many conventions, mining and processing of elements are currently subject to many restrictions. However, their large load that has already been deposited in the soil and bottom sediments can be remobilised and...
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Sustainability of Civil Structures through the Application of Smart Materials: A Review
PublikacjaEvery year, structural flaws or breakdowns cause thousands of people to be harmed and cost billions of dollars owing to the limitations of design methods and materials to withstand extreme earthquakes. Since earthquakes have a significant effect on sustainability factors, there is a contradiction between these constraints and the growing need for more sustainable structures. There has been a significant attempt to circumvent...
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Building damage due to structural pounding during earthquakes
PublikacjaEarthquake-induced pounding between adjacent buildings has been identified as one of the reasons for substantial damage or even total collapse of colliding structures. A major reason leading to interactions in buildings results from the differences in their dynamic parameters and also from insufficient distance between the structures. Although the research on structural pounding has been much advanced, the studies have mainly been...
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Behaviour of asymmetric structures with base isolation made of Polymeric Bearings
PublikacjaEarthquake-induced ground motions are the most severe and unpredictable threats to the structures all around the world. Seismic excitations cause a lot of damage in a wide variety of ways, leaving thousands of casualties in their wake. During the last few years alone, the world has witnessed many major earthquakes, five of which have caused far-reaching consequences of a national scale for Haiti (January 2010), Chile (February...
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Interactive Prototypes in Teaching User-Centred Design and Business Process Modelling
PublikacjaThis publication describes experiences gathered during the use of interactive prototyping in two areas: design of user interfaces for a touch screen information kiosk and interactive prototyping of business processes. Prototyping is promoted here as a technique useful for both visualizing design concepts and for stimulating communication within relevant teams. Developing interactive prototypes of use interfaces is discussed here...
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Partitioning of heavy metals in sub-surface flow treatment wetlands receiving high-strength wastewater
PublikacjaThe retention of heavy metals at two pilot-scale treatment wetlands (TWs), consisting of two vertical flow beds (VSSF) followed by a horizontal flow bed (HSSF) was studied. The TWs received highstrength wastewater: reject waters from sewage sludge centrifugation (RW) and landfill leachate (LL). The concentrations of metals: Fe, Mn, Zn, Al, Pb, Cu, Cd, Co, Ni were measured in treated wastewater, substrate of the beds and in plant...
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Diagnosis of Damage in a Steel Tank with Self-Supported Roof through Numerical Analysis
PublikacjaThe safety of civil engineering structures is one of the most important issues of building industry. That is why the assessment of the damage-involved structural response has recently become of major concern to engineers. Among a number of different approaches to diagnosis of damage, the method of measuring the changes in natural frequencies is considered to be one of the most effective indicators of global damage. From the practical...
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Chemical denudation and the role of sulfide oxidation at Werenskioldbreen, Svalbard
PublikacjaThis study aims to determine the rate of chemical denudation and the relationships between dominant geochemical reactions operating in the proglacial and subglacial environments of the polythermal glacier Werenskioldbreen (SW Svalbard) during an entire ablation season. Water sampling for major ion chemistry was performed at a proglacial hydrometric station and from subglacial outflows from May to September 2011. These data were...
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Culturable bacteria community development in postglacial soils of Ecology Glacier, King George Island, Antarctica
PublikacjaGlacier forelands are excellent sites in which to study microbial succession because conditions change rapidly in the emerging soil. Development of the bacterial community was studied along two transects on lateral moraines of Ecology Glacier, King George Island, by culture-dependent and culture-independent approaches (denaturating gradient gel electrophoresis). Environmental conditions such as cryoturbation and soil composition...
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The long-term properties of mineral-cement-emulsion mixtures
PublikacjaThis publication presents evaluation of long-term behavior of mineral-cement-emulsion (MCE) mixtures. MCE mixtures are among the major products of cold recycling of old asphalt pavements. They are composed by binding of the old materials reclaimed from the pavement and new mineral aggregate using two different binding agents – cement and bituminous emulsion. While bituminous emulsion dissolutes and binds materials quite fast, it...
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Reinforced concrete thin wall dome after eighty years of operation in maritime climate environment
PublikacjaThe paper presents a description of the construction elements of the Gdynia Seaport main hall dome. Firstly, it provides information about the technical condition of the dome’s structure. Secondly, it examines the strength analysis of the thin-walled reinforced concrete dome covering. Throughout the last 80 years the building has been exposed to an unfavourable marine climate. The analysis of the state of stress and deformations...
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Ionic liquids-based microextraction techniques
PublikacjaIn recent years, the development of highly efficient analytical techniques is of great importance, however, the direct analysis of complex sample matrix is still impossible in many cases. Therefore, the step of sample preparation is commonly involved in an analytical procedure. Over the years, it has been realized that the major source of inaccuracy and imprecision on general analysis results from the operations associated to sample...
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The Urban Mentoring as a New Method of Participatory Urban Planning in Poland
PublikacjaTwenty-five years after the return of democracy and the beginning of basing the country's economy on neoliberal developmental paradigm, Poland adopted the regulations regarding management of urban policy, which had been wait for over a decade (accession to the EU). The National Urban Policy as well as the Act on revitalization have defined, in a modern manner, the field of cooperation between the local government, the administration...
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Multi-objective design optimization of antenna structures using sequential domain patching with automated patch size deter-mination
PublikacjaIn this paper, a simple yet efficient and reliable technique for fully automated multi-objective design optimization of antenna structures using sequential domain patching (SDP) is discussed. The optimization procedure according to SDP is a two-step process: (i) obtaining the initial set of Pareto-optimal designs representing the best possible trade-offs between considered conflicting objectives, and (ii) Pareto set refinement...
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Comprehensive methodology for Staphylococcus aureus lipidomics by liquid chromatography and quadrupole time-of-flight mass spectrometry
PublikacjaStaphylococcus aureus is a common pathogen known to cause relatively minor infections as well as severe disorders in humans. Although there is fair amount of published data concerning various aspects of its biology, epidemiology, genetics, etc., there is still a scarce amount of data presenting reliable and thorough investigations regarding high-throughput analysis of total S. aureus lipid content. Therefore, the aim of this study...
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Effect of Individual Components of Lignocellulosic Biomass on Methane Production and Methanogen Community Structure
PublikacjaOne of the major factors that influences the economic feasibility of biogas production is the availability of digestible feedstocks. There is little research on the influence of the chemical composition of biomass on biogas synthesis, especially with regard to the content of lignocellulosic materials. Therefore, the aim of this study was to estimate how differences in the content of cellulose and lignin in lignocellulosic biomass...
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An Experimental Investigation of Pressure Wave Celerity During the Transient Slurry Flow
PublikacjaTransportation of slurries in pressure pipelines is an example of a complex flow due to specific parameters of transported medium. For practitioners, the economy of designing and maintenance is usually the most important factor. For this reason, most of hydrotransport installations are fairly simple; however, they become more vulnerable to negative effects of the transient flow which can occur in pressure pipelines. As the consequence,...
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Human serum interactions with phenolic and aroma substances of Kaffir(Citrus hystrix) and Key lime (Citrus aurantifolia) juices
PublikacjaTo understand the therapeutic application of polyphenols extracted from Kaffir (PolKaf) and Key (PolKey) limesdifferent analytical methods were applied. Based on quantitative analysis by two dimensional gas chromato-graphy (GC×GC) and time of flight mass spectrometry (TOFMS) it can be observed that the biggest differencesin the contents of selected terpenes of Kaffir and Key limes occur in chemical compounds such as limonene, citraland...
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The treatment of wastewater containing pharmaceuticals in microcosm constructed wetlands: the occurrence of integrons (int1–2) and associated resistance genes (sul1–3, qacEΔ1)
PublikacjaThe aim of this study was to analyze the occurrence of sulfonamide resistance genes (sul1–3) and other genetic elements as antiseptic resistance gene (qacEΔ1) and class 1 and class 2 integrons (int1–2) in the upper layer of substrate and in the effluent of microcosm constructed wetlands (CWs) treating artificial wastewater containing diclofenac and sulfamethoxazole (SMX), which is a sulfonamide antibiotic. The bacteria in the substrate...
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Human verbal memory encoding is hierarchically distributed in a continuous processing stream
PublikacjaProcessing of memory is supported by coordinated activity in a network of sensory, association, and motor brain regions. It remains a major challenge to determine where memory is encoded for later retrieval. Here we used direct intracranial brain recordings from epilepsy patients performing free recall tasks to determine the temporal pattern and anatomical distribution of verbal memory encoding across the entire human cortex. High...
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Fighting Administrative Corruption with Digital Government in Sub-Saharan Africa
PublikacjaAdministrative corruption is a pervasive problem and a major threat to economic and social development around the world, especially in Sub-Saharan Africa which lags behind other regions in various development indicators and is seen as one of the most corrupt regions globally. This paper examines a hypothesis that digital government – the use of digital technology to transform public administration organizations and their relationships...
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Selected aspects of two-phase flow studies using different visualization techniques in minichannels
PublikacjaThe subject of the study is to present the possibility of the use of visualization techniques in the researches on two-phase flows, carried out by the authors for many years. These works included as follows: heat transfer during the flow boiling, boiling crises and condensation in flow. The issue of the heat transfer intensification during the flow boiling through the channels of small diameters was analyzed. All this work focused...
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Linking of adjacent three-storey buildings for mitigation of structural pounding during earthquakes
PublikacjaThe reports after major earthquakes indicate that the earthquake-induced pounding between insufficiently separated buildings may lead to significant damage or even total collapse of structures. An intensive study has recently been carried out on mitigation of pounding hazards so as to minimize the structural damages or prevent collisions at all. The aim of this paper is to investigate the effectiveness of the method when two adjacent...
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Using Fast Frequency Hopping Technique to Improve Reliability of Underwater Communication System
PublikacjaAcoustic underwater communication systems designed to work reliably in shallow coastal waters must overcome major limitations such as multipath propagation and the Doppler effect. These restrictions are the reason for the complexity of receivers being built, whose task is to decode a symbol on the basis of the received signal. Additional complications are caused by the low propagation speed of the acoustic wave in the water and...
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Optimizing Ni–Cr patterned boron-doped diamond band electrodes: Doping effects on electrochemical efficiency and posaconazole sensing performance
PublikacjaThere is growing interest in developing diamond electrodes with defined geometries such as, for example, micrometer-sized electrode arrays to acquire signals for electroanalysis. For electroanalytical sensing applications, it is essential to achieve precise conductive patterns on the insulating surface. This work provides a novel approach to boron-doped diamond patterning using nichrome masking for selective seeding on an oxidized...
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A framework to analyse the probability of accidental hull girder failure considering advanced corrosion degradation for risk-based ship design
PublikacjaShip’s hull girder failure could result from maritime accident that can cause human life loss, environmental disaster, and major economic impacts. In risk-based ship design paradigm, accounting for rare phenomena (e.g. ship-ship collision or grounding) is important to provide safe and durable structure. In-service corrosion-induced hull degradation should be considered at the design stage, as it can significantly affect structural...
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Smart Approach for Glioma Segmentation in Magnetic Resonance Imaging using Modified Convolutional Network Architecture (U-NET)
PublikacjaSegmentation of a brain tumor from magnetic resonance multimodal images is a challenging task in the field of medical imaging. The vast diversity in potential target regions, appearance and multifarious intensity threshold levels of various tumor types are few of the major factors that affect segmentation results. An accurate diagnosis and its treatment demand strict delineation of the tumor affected tissues. Herein, we focus on...
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Mater-Bi/Brewers’ Spent Grain Biocomposites—Novel Approach to Plant-Based Waste Filler Treatment by Highly Efficient Thermomechanical and Chemical Methods
PublikacjaThermoplastic starch (TPS) is a homogenous material prepared from native starch and water or other plasticizers subjected to mixing at a temperature exceeding starch gelatinization temperature. It shows major drawbacks like high moisture sensitivity, poor mechanical properties, and thermal stability. To overcome these drawbacks without significant cost increase, TPS could be blended with bio-based or biodegradable polymers and...
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Reduced-Cost Microwave Modeling Using Constrained Domains and Dimensionality Reduction
PublikacjaDevelopment of modern microwave devices largely exploits full-wave electromagnetic (EM) simulations. Yet, simulation-driven design may be problematic due to the incurred CPU expenses. Addressing the high-cost issues stimulated the development of surrogate modeling methods. Among them, data-driven techniques seem to be the most widespread owing to their flexibility and accessibility. Nonetheless, applicability of approximation-based...
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Nanobiocatalysis for biofuel production
PublikacjaThe human race is relied on the use of conventional and non-renewable energy resources like fossil fuels for centuries. With the rising environmental issues linked with the use of these conventional energy resources, the trend soon shifted towards more robust and sustainable energy resources. In this regard, the different generations of biofuels have revolutionized the industrial sector by ensuring an eco-friendly and more economical...
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Exposure to cooking emitted volatile organic compounds with recirculating and extracting ventilation solutions
PublikacjaEnergy-efficient urban development leads to the compact design of apartments. Recirculating ventilation solutions are an attempt to minimize the space required for ventilation ducting, but more data on their performance are needed. Cooking is a major source of volatile organic compounds (VOCs) emissions. It is necessary to assess how well recirculating kitchen hoods perform in reducing the residents' exposure to cooking fumes compared...
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The Optimal Location of Ground-Based GNSS Augmentation Transceivers
PublikacjaModern Global Navigation Satellite Systems (GNSS) allow for positioning with accuracies ranging from tens of meters to single millimeters depending on user requirements and available equipment. A major disadvantage of these systems is their unavailability or limited availability when the sky is obstructed. One solution is to use additional range measurements from ground-based nodes located in the vicinity of the receiver. The highest...
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Multicopy Suppressor Analysis of Strains Lacking Cytoplasmic Peptidyl-Prolyl cis/trans Isomerases Identifies Three New PPIase Activities in Escherichia coli That Includes the DksA Transcription Factor
PublikacjaConsistent with a role in catalyzing rate-limiting step of protein folding, removal of genes encoding cytoplasmic protein folding catalysts belonging to the family of peptidyl-prolyl cis/trans isomerases (PPIs) in Escherichia coli confers conditional lethality. To address the molecular basis of the essentiality of PPIs, a multicopy suppressor approach revealed that overexpression of genes encoding chaperones (DnaK/J and GroL/S),...
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Non-Diophantine Arithmetics in Mathematics, Physics and Psychology
PublikacjaFor a long time, all thought there was only one geometry — Euclidean geometry. Nevertheless, in the 19th century, many non-Euclidean geometries were discovered. It took almost two millennia to do this. This was the major mathematical discovery and advancement of the 19th century, which changed understanding of mathematics and the work of mathematicians providing innovative insights and tools for mathematical research and applications...
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A Five-Leg Three-Level Dual-Output Inverter
PublikacjaClassical 3-level dual-output inverter, 3-L DOI, involves two similar 3-level inverters that provides a pair of 3-phase output voltages with same or different frequencies from common input voltage source. Flexibility of either operation of the constituting inverters is evident in this DOI; but total duplication of power switches is a major drawback. State of the art coupled 3-L DOIs reduce this drawback by providing series-shared...
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Artificial neural network prophecy of ion exchange process for Cu (II) eradication from acid mine drainage
PublikacjaThe removal of heavy metal ions from wastewater was found to be significant when the cation exchange procedure was used effectively. The model of the cation exchange process was built using an artificial neural network (ANN). The acid mine drainage waste’s Cu(II) ion was removed using Indion 730 cation exchange resin. Experimental data from 252 cycles were recorded. In a column study, 252 experimental observations validated the...
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Optimum shapes and dimensions of rubber bumpers in order to reduce structural pounding during seismic excitations
PublikacjaLarge displacement of structures observed during seismic excitations may lead to collisions between two adjacent, insufficiently-separated buildings and may result in major damages of both of them. In many building codes, appropriate equations or approximately recommended distances between structures in order to avoid pounding hazard have been introduced. Unfortunately, further, more detailed considerations show that safety situation...
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Recent advancements in molecularly imprinted polymers for the removal of heavy metal ions and dyes
PublikacjaContamination set off by highly toxic metal ions and dyes is a big threat to the environment and living beings. Various industries like metal plating, mining, pesticides, battery manufacturing, and dyeing release metal ions and toxic dyes directly into the water. It is necessary to remove these toxic substances from the environment. Molecular imprinting technology (MIT) got a lot of attention in the last two decades because of...
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KM Challenges in Small KIBS Companies: Multi-case Analysis in Two Countries
PublikacjaKnowledge Intensive Business Services (KIBS) – i.e. companies like e.g. computer services, consulting, engineering, business communication, and R&D support - are key players in the modern economies. They stimulate the innovativeness of businesses and societies. Their competitiveness is based on knowledge, which is their key production factor and also the kind of “goods” they sell. The large majority of KIBS companies have a small...
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Gender Disparity in the FinTech Sector: Systematic Literature Review
PublikacjaThe main objective of this chapter is to identify research areas of FinTech activity in which gender disparity has been observed. In addition, we shall identify how the development of FinTech reduces the gender gap. A systematic literature review using the PRISMA concept is the preferred research method. Publications were searched in the following databases: Web of Science, Scopus and Google Scholar using the formula “FinTech AND...