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Wyniki wyszukiwania dla: minimum inhibitory concentration
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Effect of antitumor compounds on the yeast topoisomerase II relaxation activity
Dane BadawczeThe datasets contain results of antitumor compounds* (known inhibitors of human topoisomerase alpha II) inhibitory activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions,...
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SZACOWANIE ZAWARTOŚCI BENZO(a)PIRENU W PYLE ZAWIESZONYM PM10 W AGLOMERACJI TRÓJMIEJSKIEJ ZA POMOCĄ WIELOWYMIAROWEJ REGRESJI LINIOWEJ=ESTIMATION OF BENZO(A)PYRENE CONTENT IN SUSPENDED DUST PM10 IN TRI-CITY AGGLOMERATION USING MULTIDIMENSIONAL LINEAR REGRESSION
PublikacjaW pracy przedstawiono próbę oszacowania przy pomocy wielowymiarowej regresji liniowej modelu empirycznego opisującego czynniki wpływające na zawartość B(a)P w pyle zawieszonym PM10 w Aglomeracji Trójmiejskiej w latach 2008-2011. Na przestrzeni tych lat średnioroczne stężenie B(a)P w PM10 wzrosło ponad dwukrotnie i ponad trzykrotnie przewyższa poziom docelowy. Z przeprowadzonych analiz wynika, że główną przyczyną wzrostu stężenia...
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Experimental research on water lubricated three layer sliding bearing with lubrication grooves in the upper part of the bush and its comparison with a rubber bearing
Publikacjacomposite. Eachofitslayershasanimportantfunction.Speciallypreparedslidingsurfaceensures minimum resistance.Followingrunning-initssmoothnessbecomesveryhighandthebearingmay continue workingunder fluid lubricationregime.NBRlayerensuresbearingelasticity,goodvibration damping propertiesandinsusceptibilitytoshaftaxismisalignment.Theexternalbrasslayermakes fitting thebearingeasier. Experiment resultsoftheconductedresearchwerecomparedwiththoseforarubberbearingof similar...
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Methane (CH4) calibration set of FTIR spectra
Dane BadawczeThe calibration spectra for CH4 concentration calibration were supplied with this dataset
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Carbon (II) oxide (CO) calibration set of FTIR spectra
Dane BadawczeThe calibration spectra for CO concentration calibration were supplied with this dataset
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Carbon dioxide (CO2) calibration set of FTIR spectra
Dane BadawczeThe calibration spectra for CO2 concentration calibration were supplied with this dataset
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Gold nanocubic structures agglomeration when put on conductive surfaces
Dane BadawczeThis dataset contains SEM images of gold nanocubes (AuNC), which were deposited at the conductive Si wafer surface and dried. The deposition method, the solvent used and AuNC concentration have a significant influence on the homogeneous distribution and their agglomeration at the surface, further influencing the electrochemical characteristics of the...
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Sposób segmentacji przebiegu losowego, złożonego z szumu białego i impulsów prostokątnych o stałych amplitudach oraz przypadkowych czasach trwania i przerw
PublikacjaPodano sposób segmentacji sygnału losowego o składowej stacjonarnej będącej szumem białym oraz niestacjonarnej w formie impulsów prostokątnych o stałych amplitudach oraz przypadkowych czasach trwania i przerw. Obserwowany sygnał jest dzielony na N segmentów, w których składowa niestacjonarna, impulsowa posiada ustaloną amplitudę. Momenty czasu, w których zaczynają się i kończą kolejne segmenty określono przez wyznaczenie minimum...
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Paired domination versus domination and packing number in graphs
PublikacjaGiven a graph G = (V(G), E(G)), the size of a minimum dominating set, minimum paired dominating set, and a minimum total dominating set of a graph G are denoted by γ (G), γpr(G), and γt(G), respectively. For a positive integer k, a k-packing in G is a set S ⊆ V(G) such that for every pair of distinct vertices u and v in S, the distance between u and v is at least k + 1. The k-packing number is the order of a largest kpacking and...
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Wyniki sulfammox (SRAO)
Dane BadawczeTwo granular sequencing batch reactors were operated for 160 days under anammox conditions, comparing the Anammox process and Sulfate Reduction Ammonium Oxidation process. The study aimed to investigate whether increasing the concentration of SO42- could enhance N removal rates under anaerobic conditions, and whether SO42- reduction and anammox processes...
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Novel Nystatin A1 derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis
PublikacjaOpportunistic oral infections caused by Candida albicans are frequent problems in immunocompromised patients. Management of such infections is limited due to the low number of antifungal drugs available, their relatively high toxicity and the emergence of antifungal resistance. Given these issues, our investigations have focused on novel derivatives of the antifungal antibiotic Nystatin A1, generated by modifications at the amino...
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Phospholipids as potential prevention factor in carcinogenesis
PublikacjaPhospholipids are a group of complex lipids, which can be used in cancer chemoprevention. Glicerophospholipids are composed of fatty acids esterified to a glycerol backbone, a phosphate group and a hydrophilic residue such as: cho- line, ethanoloamine, serine or inositol. In the sn-2 position of glicerophospholipid usually there are unsaturated fatty acids, i.e. linolenic acid, while in the sn-1 position more typi- cal are saturated...
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Drawing maps with advice
PublikacjaW pracy podejmujemy temat konstrukcji algorytmu dla agenta, który zostaje umieszczony w dowolnym wierzchołku grafu (wierzchołki są nierozróżnialne, krawędzie mają etykiety portów), po czym realizuje algorytm zmierzający do znalezienia drzewa spinającego grafu lub izomorficznej kopii grafu. Dla obu problemów podajemy asymptotycznie dokładne lub prawie dokładne oszacowania na ilość bitów dodatkowej informacji, którą agent musi otrzymać...
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Glucosinolates from lepidium peruvianum as potential antiamnestic drugs
PublikacjaLepidium peruvianum (maca) (Brassicaceae) is a naturally occurring plant mainly in the high Andes of Peru. In recent years, it has been intensively researched in terms of its influence on various diseases and towards health improvement. Alzheimer’s disease is an incurable disease that most often affects adults over the age of 60. As since 2003 the US Food and Drug Administration (FDA) did not approve any new drug for Alzheimer’s...
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Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases
PublikacjaFourteen monocyclic analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds were synthesized by the solid-phase method. The purpose of this work was to establish the role of a disulfide bridge present in inhibitor's side chains of Cys3 and Cys11 in association with serine proteinases. This cyclic fragment was replaced by the disulfide bridges formed by L-pencillamine (Pen), homo-L-cysteine (Hcy), N-sulfanylethylglycine...
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Mechanizacja napraw głównych podtorza i nawierzchni szynowych
PublikacjaSzybki rozwój techniki i znaczący wzrost kosztów pracy wymusza na wykonawcach robót ograniczenie do niezbędnego minimum liczby robotników, i wto miejsce wprowadzenie nowoczesnych, bardzo wydajnych maszyn, które skracają czas wykonania naprawy. Druga zasadniczą przyczyną wprowadzenia nowoczesnych maszyn jest ograniczenie do niezbędnego minimum czasu zamknięcia torów, co zmniejsza utrudnienia w prowadzeniu ruchu pociągów, a ponadto...
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Mechanizacja napraw głównych dróg szynowych
PublikacjaSzybki rozwój techniki i znaczący wzrost kosztów pracy wymusza na wykonawcach robót ograniczenie do niezbędnego minimum liczby robotników, i w to miejsce wprowadzenie nowoczesnych, bardzo wydajnych maszyn, które skrócą czas wykonania napraw.Drugą zasadniczą przyczyną wprowadzenia nowoczesnych maszyn jest skrócenie do niezbędnego minimum czasu zamknięcia toru, co ogranicza utrudnienia w prowadzeniu ruchu pociągów, a dodatkowo...
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Global edge alliances in graphs
PublikacjaIn the paper we introduce and study a new problem of finding a minimum global edge alliance in a graph which is related to the global defensive alliance (Haynes et al., 2013; Hedetniemi, 2004) and the global defensive set (Lewoń et al., 2016). We proved the NP-completeness of the global edge alliance problem for subcubic graphs and we constructed polynomial time algorithms for trees. We found the exact values of the size of the...
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Kinetics of the crosslinking reaction between genipin and chitosan solutions
PublikacjaThe kinetics of the chitosan crosslinking reaction with genipin was examined. The strong relationship was found between crosslinking agent concentration, chitosan concentration, temperature and gelling time. Data obtained will be used in the proper selection of optimal genipin concentration for crosslinking chitosan solutions.
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Properties of the triset metric for phylogenetic trees
Publikacjathe following paper presents a new polynomial time metric for unrootedphylogenetic trees (based on weighted bipartite graphs and the method ofdetermining a minimum perfect matching) and its properties. also many its properties are presented.
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Unicyclic graphs with equal total and total outer-connected domination numbers
PublikacjaLet G = (V,E) be a graph without an isolated vertex. A set D ⊆ V (G) is a total dominating set if D is dominating and the in- duced subgraph G[D] does not contain an isolated vertex. The total domination number of G is the minimum cardinality of a total domi- nating set of G. A set D ⊆ V (G) is a total outer–connected dominating set if D is total dominating and the induced subgraph G[V (G)−D] is a connected graph. The total outer–connected...
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Weakly convex domination subdivision number of a graph
PublikacjaA set X is weakly convex in G if for any two vertices a; b \in X there exists an ab–geodesic such that all of its vertices belong to X. A set X \subset V is a weakly convex dominating set if X is weakly convex and dominating. The weakly convex domination number \gamma_wcon(G) of a graph G equals the minimum cardinality of a weakly convex dominating set in G. The weakly convex domination subdivision number sd_wcon (G) is the minimum...
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TiO2-TG analyses -OH groups
Dane BadawczeTG analyses of TiO2 were performed under nitrogen flow to monitor desorption of hydroxyl groups. Physisorbed weak-bonded hydroxyl groups were desorbed totally at around 120oC, whereas chemisorbed ones at around 500oC. The mass loss at these temperatures was used as concentration of hydroxyl groups on TiO2 surface. The amount of analysed TiO2 was 10...
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Critical minima in elastic scattering of electrons from Ar and Zn.
PublikacjaDokonano obliczeń różniczkowych przekrojów czynnych na sprężyste rozpraszanie elektronów na atomach argonu i cynku. Otrzymane minimum krytyczne z tych przekrojów porównano z niedawno otrzymanymi danymi doświadczalnymi.
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Modelowanie procesów nierównowagowych, W/C ,Energetyka. sem 1, lato 23/24PG_00057424
Kursy OnlinePrzedstawienie głównych mechanizmów i praw dotyczących termodynamiki procesów nierównowagowych. Zapoznanie z podejściami do analizy procesów nierównowagowych. Analiza przykładów procesów nierównowagowych i ich opis. Wprowadzenie do zagadnień związanych z analizą procesów za pomocą kryterium minimum produkcji entropii
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The impact of equity pledge on inefficient investment: a perspective from family entrepreneurship
PublikacjaAs an efficient and convenient financing method, equity pledges may have a heterogeneous impact on the inefficient investment of family firms. In order to verify this point, this paper takes A-share listed family enterprises from 2010 to 2021 as a research sample. It conducts an empirical test on the impact of equity pledges on inefficient investment in family firms by constructing a panel regression model. The results show...
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Phosphate tricyclic coumarin analogs as steroid sulfatase inhibitors: synthesis and biological activity.
PublikacjaIn the present work, we report convenient methods for the synthesis and biological evaluation of phosphate tricyclic coumarin derivatives as potential steroid sulfatase inhibitors. The described synthesis includes the straightforward preparation of 7-hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one, 3-hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one and 3-hydroxy-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-6-one modified...
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Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
PublikacjaAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....
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Feature Reduction Using Similarity Measure in Object Detector Learning with Haar-like Features
PublikacjaThis paper presents two methods of training complexity reduction by additional selection of features to check in object detector training task by AdaBoost training algorithm. In the first method, the features with weak performance at first weak classifier building process are reduced based on a list of features sorted by minimum weighted error. In the second method the feature similarity measures are used to throw away that features...
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On extremal sizes of locally k-tree graphs
PublikacjaA graph G is a locally k-tree graph if for any vertex v the subgraph induced by the neighbours of v is a k-tree, k>=0, where 0-tree is an edgeless graph, 1-tree is a tree. We characterize the minimum-size locally k-trees with n vertices. The minimum-size connected locally k-trees are simply (k + 1)-trees. For k >= 1, we construct locally k-trees which are maximal with respect to the spanning subgraph relation. Consequently, the...
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Edge subdivision and edge multisubdivision versus some domination related parameters in generalized corona graphs
PublikacjaGiven a graph G= (V, E), the subdivision of an edge e=uv∈E(G) means the substitution of the edge e by a vertex x and the new edges ux and xv. The domination subdivision number of a graph G is the minimum number of edges of G which must be subdivided (where each edge can be subdivided at most once) in order to increase the domination number. Also, the domination multisubdivision number of G is the minimum number of subdivisions...
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SEM micrographs of Ti tooth implant corrosion
Dane BadawczeThe dataset contains micrographs made with a scanning electron microscope (SEM) Hitachi S-3400N of the tooth implant removed after inflammation. The inflammation was induced by the increased corrosion rate of the titanium screw. The reason for the corrosion to occur was the appearance of the concentration cell of different aeration for various areas...
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Konzetrationslöschung durch Energieübertragung bei der Lumineszenz von Lösungen
PublikacjaThe absorption spectra and quantum yields of the fluorescence of rhodamine 6 G are investigated in two different water-glycerol mixtures as a function of the rhodamine concentration. The observed concentration quenching is attributed to the formation of rhodamine dimers and the decrease in quantum yield is compared with theoretical concepts about concentration quenching by energy transfer to the dimers.
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Geometric working volume of a satellite positive displacement machine
PublikacjaThis article describes a method for determining the geometric working volume of satellite positive displacement machines (pump and motor). The working mechanism of these machines is satellite mechanism consisting of two non-circular gears (rotor and curvature) and circular gears (satellites). Two variants of the satellite mechanism are presented. In the first mechanism, the rolling line of the rotor is a sinusoid "wrapped" around...
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Fatty acids as molecular carriers in cleavable antifungal conjugates
PublikacjaConjugates composed of C2-18 fatty acid (FA) residues as a molecular carrier and 5-fluorocytosine (5-FC) as an active agent, released upon the action of intracellular esterases on the ester bond between FA and “trimethyl lock” intramolecular linker, demonstrate good in vitro activity against human pathogenic yeasts of Candida spp. The minimal inhibitory concentrations (MIC) values for the most active conjugates containing caprylic...
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Occurrence and Levels of Biogenic Amines in Beers Produced by Different Methods
PublikacjaThe concentration of biogenic amines (BAs) in beer depends, among other factors, on the activity of microorganisms, in particular lactic acid bacteria. In this work an analytical method based on derivatization with tosyl chloride and high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was used to determine 17 BAs in samples of commercially available beers, and to monitor the changes in concentration of...
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Determination of changes in viscosity of high-fructose syrup stability of pectin hydrogels depending on the temperature (25-96 Celsius degrees).
Dane BadawczeThe rheological characteristics of the high-fructose syrup modified stability of pectin (added in a concentration 2% m/m) were made on the basis of the viscosity assessment using a Brookfield viscometer with an LV SC4 - 25 spindle and a shear rate of 0,22 s-1 in the temperature range 25-96 ° C. The data allowed selection of optimal conditions for the...
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Bacteriological and physicochemical monitoring of coastal sea waters – Gulf of Gdańsk (Baltic Sea) in 2004
Dane BadawczeThe dataset contains the results of a bacteriological and physicochemical studies of Gdansk Bay coastal waters within the administrative boundaries of Gdańsk city in 2004. The examined material consisted of water samples collected from 15 sampling points. Number of Escherichia coli, number of intestinal enterococci, presence of Salmonella sp., pH, temperature,...
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Bacteriological and physicochemical monitoring of coastal sea waters – Gulf of Gdańsk (Baltic Sea) in 2006
Dane BadawczeThe dataset contains the results of a bacteriological and physicochemical studies of Gdansk Bay coastal waters within the administrative boundaries of Gdańsk city in 2006. The examined material consisted of water samples collected from 15 sampling points. Number of Escherichia coli, number of intestinal enterococci, presence of Salmonella sp., pH, temperature,...
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Bacteriological and physicochemical monitoring of coastal sea waters – Gulf of Gdańsk (Baltic Sea) in 2007
Dane BadawczeThe dataset contains the results of a bacteriological and physicochemical studies of Gdansk Bay coastal waters within the administrative boundaries of Gdańsk city in 2007. The examined material consisted of water samples collected from 15 sampling points. Number of Escherichia coli, number of intestinal enterococci, presence of Salmonella sp., pH, temperature,...
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Isolation Number versus Domination Number of Trees
PublikacjaIf G=(VG,EG) is a graph of order n, we call S⊆VG an isolating set if the graph induced by VG−NG[S] contains no edges. The minimum cardinality of an isolating set of G is called the isolation number of G, and it is denoted by ι(G). It is known that ι(G)≤n3 and the bound is sharp. A subset S⊆VG is called dominating in G if NG[S]=VG. The minimum cardinality of a dominating set of G is the domination number, and it is denoted by γ(G)....
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Weakly convex and convex domination numbers of some products of graphs
PublikacjaIf $G=(V,E)$ is a simple connected graph and $a,b\in V$, then a shortest $(a-b)$ path is called a $(u-v)$-{\it geodesic}. A set $X\subseteq V$ is called {\it weakly convex} in $G$ if for every two vertices $a,b\in X$ exists $(a-b)$- geodesic whose all vertices belong to $X$. A set $X$ is {\it convex} in $G$ if for every $a,b\in X$ all vertices from every $(a-b)$-geodesic belong to $X$. The {\it weakly convex domination number}...
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Three-objective antenna optimization by means of kriging surrogates and domain segmentation
PublikacjaIn this paper, an optimization framework for multi-objective design of antenna structures is discussed which exploits data-driven surrogates, a multi-objective evolutionary algorithm, response correction techniques for design refinement, as well as generalized domain segmentation. The last mechanism is introduced to constrain the design space region subjected to sampling, which permits reduction of the number of training data samples...
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Divulging the anti-acetylcholinesterase activity of Colletotrichum lentis strain KU1 extract as sustainable AChE active site inhibitors
PublikacjaAlzheimer’s disease (AD), also called senile dementia is a neurodegenerative disease seen commonly in the elderly and is characterised by the formation of β-amyloid plaques and neurofbrillary tangles (NFT). Though a complete understanding of the disease is lacking, recent studies showed the role of the enzyme acetylcholinesterase (AChE) in pathogenesis. Finding new lead compounds from natural sources has always been a quest for...
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Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity
PublikacjaIn the last few years,increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory. There are several antifungal compounds whichare highly effective in some cases, however, they have limitations in usage: Nephrotoxicity and other adverse effects. In addition, the frequent use of available fungistatic drugs promotes drug resistance....
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Organic Acids and Polyphenols Determination in Polish Wines by Ultrasound-Assisted Solvent Extraction of Porous Membrane-Packed Liquid Samples
PublikacjaIn the near future, Poland is going to have more and more favorable conditions for viticulture. Organic acids and polyphenols are among the most commonly analyzed compounds due to their beneficial properties for human health and their importance in the winemaking process. In this work, a new technique involving ultrasound-assisted solvent extraction of porous membrane-packed liquid samples (UASE-PMLS) was for the first time described...
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Antifungal Activity and Synergism with Azoles of Polish Propolis
PublikacjaThe aim of our work was to check if one of the products of natural origin, namely honey 19 bee propolis may be an alternative or supplement to currently used antifungal agents. The activity 20 of 50 ethanolic extracts of propolis (EEPs), harvested in Polish apiaries, was tested on a group of 69 21 clinical isolates of C. albicans. Most of the EEPs showed satisfactory activity, with minimum 22 fungicidal concentrations (MFC) mainly...
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Activity of isavuconazole and other triazole derivatives against clinical isolates of Aspergillus fumigatus
PublikacjaAspergillus fumigatus is the most frequent pathogen of the genus Asperillus, which is highly susceptible to triazole derivatives, especially to isavuconazole and voriconazole. Many countries face a growing problem of infections due to A. fumigatus showing acquired resistance to one or several triazoles. In medical centres, monitoring the susceptibility of isolated Aspergillus spp. is recommended. The aim of this study was to collect...
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Results of experimental research of hydraulic satellite motor
Dane BadawczeThe study of the flow rate in the motor and the torque on the motor shaft at low constant speed were carried out.The file contains measurement data of the torque on the motor shaft and the flow rate in the motor as a function of the angle of shaft rotation at various constant pressure drops in the motor.
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Cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).