Filtry
wszystkich: 1779
wybranych: 1547
-
Katalog
- Publikacje 1547 wyników po odfiltrowaniu
- Czasopisma 25 wyników po odfiltrowaniu
- Konferencje 2 wyników po odfiltrowaniu
- Osoby 36 wyników po odfiltrowaniu
- Wynalazki 2 wyników po odfiltrowaniu
- Projekty 5 wyników po odfiltrowaniu
- Zespoły Badawcze 1 wyników po odfiltrowaniu
- Kursy Online 20 wyników po odfiltrowaniu
- Dane Badawcze 141 wyników po odfiltrowaniu
Filtry wybranego katalogu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: STARBURST AMINES
-
Nonlinear free and forced vibrations of a dielectric elastomer-based microcantilever for atomic force microscopy
PublikacjaThe majority of atomic force microcode (AFM) probes work based on piezoelectric actuation. However, some undesirable phenomena such as creep and hysteresis may appear in the piezoelectric actuators that limit their applications. This paper proposes a novel AFM probe based on dielectric elastomer actuators (DEAs). The DE is modeled via the use of a hyperelastic Cosserat model. Size effects and geometric nonlinearity are included...
-
A Review of Hyperelastic Constitutive Models for Dielectric Elastomers
PublikacjaDielectric elastomers are smart materials that are essential components in soft systems and structures. The core element of a dielectric elastomer is soft matter, which is mainly rubber-like and elastomeric. These soft materials show a nonlinear behaviour and have a nonlinear strain-stress curve. The best candidates for modelling the nonlinear behaviour of such materials are hyperelastic strain energy functions. Hyperelastic functions...
-
Nonlinear Free and Forced Vibrations of a Hyperelastic Micro/Nanobeam Considering Strain Stiffening Effect
PublikacjaIn recent years, the static and dynamic response of micro/nanobeams made of hyperelasticity materials received great attention. In the majority of studies in this area, the strain-stiffing effect that plays a major role in many hyperelastic materials has not been investigated deeply. Moreover, the influence of the size effect and large rotation for such a beam that is important for the large deformation was not addressed. This...
-
Application of a magnetically separable Zr-MOF for fast extraction of palladium before its spectrophotometric detection
Publikacja -
Facilitated diffusion of glucosamine-6-phosphate synthase inhibitors enhances their antifungal activity
PublikacjaKwas N-3(4-metoksyfumaroilo)-L-2,3-diaminopropanowy (FMDP) i 2-amino-2-deo-ksy-D-glucitolo-6-fosforan (ADGP) są silnymi inhibitorami syntazy glukoza-mino-6-fosforanu, istotnego enzymu grzybowego, jednak ich aktywność przeciwgrzybowa jest słaba, ze względu na powolną penetrację tych związków przez błonę cytoplazmatyczną. W tej pracy badaliśmy możliwość poprawy działania przeciwgrzybowego ADGP i FMDP poprzez zwiększenie ich własności...
-
Road safety analysis in Poland using time-series modelling techniques
PublikacjaA number of international studies argue that there is a correlation between the number of traffic fatalities and the degree of public activity. The studies use the unemployment rate to support that argument. As unemployment grows miles travelled fall, a factor known to affect road safety. This relationship seems to be true for Poland, as well. The model presented in the paper is intended to prove it. It is a structural time-series local...
-
CYP3A4-dependent cellular response does not relate to CYP3A4-catalysed metabolites of C-1748 and C-1305 acridine antitumor agents in HepG2 cells
PublikacjaHigh CYP3A4 expression sensitizes tumor cells to certain antitumor agents while for others it can lower their therapeutic ef fi cacy. We have elucidated the in fl uence of CYP3A4 overexpression on the cellular response induced by antitumor acridine derivatives, C-1305 and C-1748, in two hepatocellular carcinoma (HepG2) cell lines, Hep3A4 stably transfected with CYP3A4 isoenzyme, and HepC34 expressing empty vector. The compounds...
-
A new B-D-galactosidase with a low temperature optimum isolated from the Antarctic Arthrobacter sp. 20B: gene cloning, purification and characterization.
PublikacjaA psychrotrophic bacterium producing a coldadaptedB-galactosidase upon growth at low temperatureswas classiWed as Arthrobacter sp. 20B. A genomic DNAlibrary of strain 20B introduced into Escherichia coliTOP10F' and screening on X-Gal (5-bromo-4-chloro-3-indolyl-B-D-galactopyranoside)-containing agar plates ledto the isolation of B-galactosidase gene. The B-galactosidasegene (bgaS) encoding a protein of 1,053 amino acids,with a...
-
Numerical analysis of vacuum drying of a porous body in the integrated domain
Publikacjan the present study, the vacuum drying process of an apple slice is numerically modeled based on a control volume method. Transient two-dimensional Navier– Stokes, energy, moisture, and Luikov equations are solved by numerical coding (Fortran) to simulate the simultaneous heat and mass transfer in the ambient and apple slice, respectively. The privilege of using Luikov's model is that the capillary forces are considered, and a...
-
Biochemical, Structural Analysis, and Docking Studies of Spiropyrazoline Derivatives
PublikacjaIn this study, we evaluated the antiproliferative potential, DNA damage, crystal struc‐ tures, and docking calculation of two spiropyrazoline derivatives. The main focus of the research was to evaluate the antiproliferative potential of synthesized compounds towards eight cancer cell lines. Compound I demonstrated promising antiproliferative properties, especially toward the HL60 cell line, for which IC50 was equal to 9.4 μM/L....
-
Molecular basis of essentiality of early critical steps in the lipopolysaccharide biogenesis in Escherichia coli K-12: requirement of MsbA, cardiolipin, LpxL, LpxM and GcvB
PublikacjaTo identify the physiological factors that limit the growth of Escherichia coli K-12 strains synthesizing minimal lipopolysaccharide (LPS), we describe the first construction of strains devoid of the entire waa locus and concomitantly lacking all three acyltransferases (LpxL/LpxM/LpxP), synthesizing minimal lipid IVA derivatives with a restricted ability to grow at around 21 °C. Suppressors restoring growth up to 37 °C of Δ(gmhD-waaA)...
-
Possibilities for Developing Electromobility by Using Autonomously Powered Trolleybuses Based on the Example of Gdynia
PublikacjaTrolleybus transport refers to contemporary challenges related to a reduction in emissions of greenhouse gases and CO2 into the atmosphere formulated by international institutions, such as the United Nations, the Organisation for Security and Co-operation in Europe, or the European Union. Departure from fossil fuels in urban transport is one of the key challenges for the coming years. Trolleybuses are an important tool in this...
-
PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
PublikacjaIschemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...
-
A new Toxoplasma gondii chimeric antigen containing fragments of SAG2, GRA1, and ROP1 proteins—impact of immunodominant sequences size on its diagnostic usefulness
PublikacjaThis study presents the first evaluation of new Toxoplasma gondii recombinant chimeric antigens containing three immunodominant regions of SAG2, GRA1, and one of two ROP1 fragments differing in length for the serodiagnosis of human toxoplasmosis. The recombinant chimeric antigens SAG2-GRA1-ROP1L (with large fragment of ROP1, 85-396 amino acid residues) and SAG2-GRA1-ROP1S (with a small fragment of ROP1, 85-250 amino acid residues)...
-
Surrogate-assisted EM-driven miniaturization of wideband microwave couplers by means of co-simulation low-fidelity models
PublikacjaThis article proposes a methodology for rapid design optimization of miniaturized wideband couplers. More specifically, a class of circuits is considered, in which conventional transmission lines are replaced by their abbreviated counterparts referred to as slow-wave compact cells. Our focus is on explicit reduction of the structure size as well as on reducing the CPU cost of the design process. For the sake of computational feasibility,...
-
Novel single-stranded DNA-binding protein from psyvhrophilic bacterium Psychrobacter arcticus
PublikacjaTo study the biochemical properties of SSB from Psychrobacter arcticus (ParSSB), we have cloned the ssb genes obtained by PCR and have developed Escherichia coli overexpression systems. The gene consists of an open reading frame of 642 nucleotides encoding SSB protein of 213 amino acids with a calculated molecular mass of 22.8 kDa. The amino-acid sequence of ParSSB exhibits 49% identity and 57% similarity to Escherichia coli SSB....
-
A highly thermostable, homodimeric single-stranded DNA-binding protein from Deinococcus radiopugnans
PublikacjaWe report the identification and characterization of the single-stranded DNA-binding protein (SSB) from the mesophile and highly radiation-resistant Deinococcus radiopugnans (DrpSSB). PCR-derived DNA fragment containing the complete structural gene for DrpSSB protein was cloned and expressed in Escherichia coli. The gene consisting of an open reading frame of 900 nucleotides encodes a protein of 300 amino acids with a calculated...
-
Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublikacjaMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
-
New Screening Protocol for Effective Green Solvents Selection of Benzamide, Salicylamide and Ethenzamide
PublikacjaNew protocol for screening efficient and environmentally friendly solvents was proposed and experimentally verified. The guidance for solvent selection comes from computed solubility via COSMO-RS approach. Furthermore, solute-solvent affinities computed using advanced quantum chemistry level were used as a rationale for observed solvents ranking. The screening protocol pointed out that 4-formylomorpholine (4FM) is an attractive...
-
A Measurement-Based Approach for Speed Control of Induction Machines
PublikacjaThis paper presents an approach to design a measurement-based controller for induction machines. The proposed control approach is motivated by the fact that developing an appropriate mechanical model of such induction machines is a challenging task. Since our proposed control methodology is only on the basis of measured data, the controller design does not require any information about the model of the mechanical part. The control...
-
Applying Web 2.0 Concepts to Creating Energy Planning Portal
PublikacjaCommunity authorities in Europe are tasked to create Advanced Local Energy Plans (ALEP), which encompasses collecting local data on current energy use and generation, as well as generating future development scenarios. Both the data and the development scenarios must be publicly accessible as a basis for energy-related decisions taken by residents, local companies and other local institutions. The data must partially be collected...
-
Applying agiile practices to the development of safety-critical software
PublikacjaDevelopment of safety critical software is subjected to numerous restrictions and recommendations. To meet these requirements classical software development models (e.g. V-model) are usually applied. Agile methodologies, although rapidly increasing their popularity, were generally regarded as unsuitable for such projects. However, they offer potential benefits which provide a strong incentive to incorporate them into safety-critical...
-
Novel Diazocrowns with Pyrrole Residue as Lead(II) Colorimetric Probes
PublikacjaNovel 18- and 23-membered diazomacrocycles were obtained with satisfactory yields by diazocoupling of aromatic diamines with pyrrole in reactions carried under high dilution conditions. X-ray structure of macrocycle bearing five carbon atoms linkage was determined and described. Compounds were characterized as chromogenic heavy metal ions receptors. Selective color and spectral response for lead(II) was found in acetonitrile and...
-
Possible effects of the 1984 St. Clair River ice jam on bed changes
PublikacjaThis study examines the possible effect of the record ice jam of 1984 in the St. Clair River on river bed changes and conveyance. Numerical simulations were made to examine the flow and bed shear stresses during the jam formation and release periods. Simulation results indicate that the ice jam in the river did not cause a significant increase in bed shear stress compared to pre- and post-jam open water conditions. The insignificant...
-
Alternative cogeneration thermodynamic cycles for domestic ORC
PublikacjaThe Organic Flash Cycle (OFC) is suggested as a vapor power cycle that could potentially improve the efficiency of utilization of the heat source. Low and medium temperature finite thermal sources are considered in the cycle. Additionally the OFC’s aim is to reduce temperature difference during heat addition. The study examines 2 different fluids. Comparisons are drawn between the OFC and an optimized basic Organic Rankine Cycle...
-
Valuation of architectural heritage by multicultural student groups
PublikacjaIn this article, the author addresses the education of architecture students in the field of architectural history and the determination of the value of architectural objects. Important changes at present are underway concerning this. Both the role of architectural history in architectural education and content in architectural history curricula is changing. The need for re-evaluation...
-
Examining Ownership Equity as a Psychological Factor on Tourism Business Failure Forecasting
PublikacjaThis paper examines ownership equity as a predictor of future business failure within the tourism and hospitality sectors. The main goals of this study were to examine which ratios are the most important for a tourism business failure forecasting model and how significant is the “total percentage of equity ownership by company directors” ratio compared with other ratios associated with the probability of bankruptcy. A stepwise...
-
Georg Simmel’s The Philosophy of Money and the Modernization Paradigm
PublikacjaThis article examines Georg Simmel’s contribution to the understanding of how money functions in modern society, mainly scrutinizing his most important work on that topic, The Philosophy of Money, in the context of modernization theories. Modernization theories, as developed (most notably) by Marx, Weber, Durkheim, and Elias, attempted to explain the transition from feudalism and a closed agrarian economy to capitalism and industrial...
-
Semi-definite programming and quantum information
PublikacjaThis paper presents a comprehensive exploration of semi-definite programming (SDP) techniques within the context of quantum information. It examines the mathematical foundations of convex optimization, duality, and SDP formulations, providing a solid theoretical framework for addressing optimization challenges in quantum systems. By leveraging these tools, researchers and practitioners can characterize classical and quantum correlations,...
-
Hedging Strategies of Derivatives Instruments for Commodity Trading Entities
PublikacjaHedging as an outcome of risk management arises to account several questions. Mentioned aspect of size of the hedging is one of them. Latter questioning refers to whether producer of manufacturer are willing to secure entire exposure, when the hedging should start, now or later in the future, what is the vision on market like direction of market, time of interest, magnitude of exposure, what would be the preferred instruments of...
-
Landscape, EIA and decision-making. A case study of the Vistula Spit Canal, Poland
PublikacjaAlthough landscapes are often considered public goods, they frequently receive inadequate attention in Environmental Impact Assessments (EIAs), particularly in Poland. This neglect often leads to visible degradation during investment processes. This article examines the case of the Vistula Spit Canal, currently the largest engineering project under construction in Poland. We analysed whether the conclusions drawn in the EIA report,...
-
Digitalization and digital skills development patterns. Evidence for European countries
PublikacjaThis chapter contextualizes the digitalization process and the digital skills concept. It discusses the very process of technology diffusion, emphasizing several unique features of digital technologies that make them globally available. Next, it turns to the digital skills concept, clarifying how and why they reshape the societal and economic landscape. It also briefly addresses the digital divide and skill-biased technological...
-
Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase
PublikacjaCentra aktywne izomerazy fosfoglukozowej (PGI) oraz domeny izomerazowej (HPI) syntazy glukozamino-6-fosforanu (GlcN-6-P), wykazują podobieństwo ułożenia przestrzennego kluczowych reszt aminokwasowych, z wyjątkiem reszty Arg272 PGI i reszt Lys603 i Lys485 HPI. Dziesięć pochodnych D-heksitolo-6-P, kwasu 5-fosfoarabonowego i kwasu 6-fosfoglukonowego, strukturalnych analogów cis-enolaminy lub cis-enolanu, przypuszczalnych stanów przejściowych...
-
Przejazdy kolejowe na modernizowanych i rewitalizowanych liniach kolejowych - przepisy a rzeczywistość
PublikacjaPrzy modernizacji i rewitalizacji dróg szynowych jednym z elementów infrastruktury, wymagającym szczególnej uwagi już na etapie planowania inwestycji, są przejazdy i przejścia w poziomie szyn. Obowiązujące przepisy krajowe pochodzą z lat 90. ubiegłego wieku i w wielu aspektach nie uwzględniają specyfiki najczęściej obecnie występujących na liniach kolejowych inwestycji modernizacyjnych i rewitalizacyjnych. W przypadku linii należących...
-
Convenient Synthesis of Functionalized Unsymmetrical Vinyl Disulfides and Their Inverse Electron-Demand Hetero-Diels-Alder Reaction
PublikacjaThe simple, convenient, and efficient methods for the preparation of unsymmetrical vinyl disulfides with additional functional groups under mild conditions with moderate to high yields were designed. The developed methods include the reaction of S-vinyl phosphorodithioate with thiotosylates or S-vinyl thiotosylate with thiols. The designed methods allow for the synthesis of unsymmetrical vinyl disulfides with additional functionalities...
-
Selected organophosphorus compounds with biological activity. Applications in medicine
PublikacjaThe purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings...
-
The Finite Elements Method application to assesment the impact of turbulence generated by wind turbines on their lacation inclose proximity of overhead high voltage power transmissionlines
PublikacjaThe paper presents selected aspects of construction of wind turbines location concerning aerodynamic impact on power lines. Reaserch is based on the source data concerning the aerodynamic impact of a wind farm consisting of 8 turbines and 400 kV power line, an analysis of the possibility of wind farm locating in the immediate vicinity of the line was carried out. There are serious problems with locating higher capacity wind farms...
-
DESIGN AND EXECUTION ERRORS AS A CAUSE OF DAMAGE TO ANTI- ELECTROSTATIC FLOORING
PublikacjaApart from technological lines, industrial floors are a key element in the scope of maintaining the continuity of work of both production plants and logistics centers. The constantly developing industry of industrial flooring includes both classic design and technological flooring solutions, as well as specialist solutions used in facilities where technological processes or storage require system protection against static electricity....
-
Application of safirinium N-hydroxysuccinimide esters to derivatization of peptides for high-resolution mass spectrometry, tandem mass spectrometry, and fluorescent labeling of bacterial cells
PublikacjaMass spectrometry methods are commonly used in the identification of peptides and biomarkers. Due to a relatively low abundance of proteins in biological samples, there is a need for the development of novel derivatization methods that would improve MS detection limits. Hence, novel fluorescent N-hydroxysuccinimide esters of dihydro-[1,2,4]triazolo[4,3-a]pyridin-2-ium carboxylates (Safirinium P dyes) have been synthesized. The...
-
Flame retardant epoxy/halloysite nanotubes nanocomposite coatings: Exploring low-concentration threshold for flammability compared to expandable graphite as superior fire retardant
PublikacjaEpoxy nanocomposites containing halloysite nanotubes (HNTs) were developed and their low-concentration thresholds for thermal stability and flame retardancy were compared with that of epoxy system containing expandable graphite (EG), as a reference with superior flame retardancy. The effects of HNTs and EG on the peak of Heat Release Rate (pHRR), Total Heat Release (THR), and Time-To-Ignition (TTI) of the prepared samples were...
-
The influence of different glycerine purities on chemical recycling process of polyurethane waste and resulting semi‐products
PublikacjaChemical recycling is the most favourable recycling method due to the possibility of polyol recovery. This work is dedicatedto the utilisation of crude glycerine and polyurethane waste. It aims at determining the impact of the use of glycerine fromthe production of biodiesel with various degrees of purity as a cleavage agent on the decomposition process of polyurethanefoam. The influence of glycerine purit y on the chemical structure...
-
Humanizacja traktu porodowego
PublikacjaPowszechny w latach 80-tych XX wieku zmedykalizowany model porodu podlega stopniowej humanizacji. Artykuł omawia współczesne tendencje w podejściu do porodu i ich wpływ na układ funkcjonalno-przestrzenny traktu porodowego. Przedstawia najważniejsze wymagania stawiane obecnie traktom porodowym. Na podstawie przykładów rozwiązań realizacyjnych i projektowych analizuje problematykę modernizacji zespołów porodowych w Polsce.
-
Designing drainage systems – possible application of advanced calculations and hydrodynamical modeling
PublikacjaNowadays we can observe a faster development of drainage systems than ever. This gives us an opportunity to de- sign more efficient systems that can cope with the rapid growth of cities and, what comes with it, impervious surfaces. Here the question arises, whether traditional methods used in drainage system design are potent enough to cope with the emerging prob- lems and difficulties. In this paper we will make...
-
English, French, and Polish Aliases of Criminals: Diversity of Inspirations in their Creation and Typical Nicknaming Schemes
PublikacjaThe present paper examines the topic of aliases of criminals, which seems to be understudied in linguistic research. Therefore, this article’s primary goal is to describe how criminals’ aliases are created and what are the differences and similarities in that process in English, French, and Polish. Firstly, the theoretical background concerning the topic of pseudonyms is presented. Then, the corpus gathered for this paper (available...
-
Tuning matrix-vector multiplication on GPU
PublikacjaA matrix times vector multiplication (matvec) is a cornerstone operation in iterative methods of solving large sparse systems of equations such as the conjugate gradients method (cg), the minimal residual method (minres), the generalized residual method (gmres) and exerts an influence on overall performance of those methods. An implementation of matvec is particularly demanding when one executes computations on a GPU (Graphics...
-
Zwierzę, które spać nie może. Bezsenność w antropologii filozoficznej Emila Ciorana
PublikacjaThis article examines the role of insomnia in Emil Cioran’s philosophy. Taken as a whole, his work appears to be exceptionally significant both from the point of view of anthropology and illness narrative studies. There has never been any doubt that his life and work are dominated by a sense of ennui, loneliness and estrangement. Yet these themes are merely symptoms of more fundamental problems he grappled with, i.e. the grotesque...
-
Do new EU members have any chance of earning as much as Westerns do?
PublikacjaThis article examines the wage dispersion in the European Union in the last ten years (1996-2006). The research is motivated by the fact that New Members States (NMS) expected that wage convergence would occurred after their accession to the EU. At the same time Old Member States (OMS) have been increasingly concerned with the possibility that the EU enlargement could influence their local labor markets and wages through new channels...
-
Market Regeneration in Line with Sustainable Urban Development
PublikacjaThis article presents the study of the optimal design solutions for regeneration of marketplaces. It examines the design variants for the revitalisation of the marketplace, in particular, investment in their modernisation in order to find the most optimal model for transforming these public spaces to have a significant impact on the city’s development. The research is a comparative analysis of the implementation of regeneration...
-
Theological Intersections: Newman’s ‘Primacy of God’ in Modern Church Discourse
PublikacjaThis article critically examines the Catholic–Anglican theological dialogue, centering on John Henry Newman’s ‘Primacy of God’, Catholic synodality, and Anglican comprehensiveness. It illuminates the interconnectedness of these elements, revealing their potential to enhance ecumenical conversations. Newman’s concept of communal faith and divine primacy resonates across both traditions, advocating a transformative,...
-
Measurements of ASON/GMPLS connection control layer performance according to the ETSI methodology
PublikacjaMeasurements of performance have always been crucial for evaluation of telecommunication systems, especially for implementation of network control elements responsible for connection handling which regards to bandwidth reservation, modification and release. That problem also arises in Automatically Switched Optical Network/Generalized Multiprotocol Label Switching (ASON/GMLPS) architecture, which is considered as one of the components...