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Wyniki wyszukiwania dla: PSORIASIS GENETICS, GWAS, EPIGENETIC CHANGES, MIRNA
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Potential Predictive Value of Serum Pentraxin 3 and Paraoxonase 1 for Cardiometabolic Disorders Development in Patients with Psoriasis—Preliminary Data
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Elimination of wild-type P53 mRNA in glioblastomas showing heterozygous mutations of P53
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Different Patterns of mRNA Nuclear Retention during Meiotic Prophase in Larch Microsporocytes
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The Genesis of Homonymy of the Finnish Language
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Kinetics of carrier recombination in amorphous solids
PublikacjaPrzeanalizowano zależność pomiędzy teoriami Simmonsa-Taylora oraz Rose´a, opisującą niestacjonarne procesy rekombinacji nośników nadmiernych, ich pułapkowania i uwalniania ze stanów zlokalizowanych. Równania Simmonsa-Taylora wyrażono w warunkach gęstości nośnika w stanach zlokalizowanych. Pokazano, że w pewnych przypadkach równania redukują się do równań Rose´a, odnoszących się do bimolekularnej lub monomolekularnej rekombinacji.
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In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
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Evaluation of CD40, its ligand CD40L and Bcl-2 in psoriatic patients
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Serum adiponectin and leptin levels in psoriatic patients according to topical treatment
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Chemical and Genetic Diversity of Nodularia spumigena from the Baltic Sea
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The presence of prostate cancer at biopsy is predicted by a number of genetic variants
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Specialized genetic operators in drinking water distribution systems control
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How to support patients with BRCA genetic mutation? Research review.
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Comparison of reproduction strategies in genetic algorithm approach to graph searching
Publikacjagenetic algorithms (ga) are a well-known tool used to obtain approximate solutions to optimization problems. successful application of genetic algorithm in solving given problem is largely dependant on selecting appropriate genetic operators. selection, mutation and crossover techniques play a fundamental role in both time needed to obtain results and their accuracy. in this paper we focus on applying genetic algorithms in calculating...
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Analysis of Keratoconus genetic factors within Keratoconus Loci and mtDNA
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A Parallel Genetic Algorithm for Creating Virtual Portraits of Historical Figures
PublikacjaIn this paper we present a genetic algorithm (GA) for creating hypothetical virtual portraits of historical figures and other individuals whose facial appearance is unknown. Our algorithm uses existing portraits of random people from specific historical period and social background to evolve a set of face images potentially resembling the person whose image is to be found. We then use portraits of the person's relatives to judge...
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Ecosensitivity and genetic polymorphism of somatic traits in the perinatal development of twins
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Chapter 13 Geneticization and Bioethics: Ethical Dilemmas in Genetic Counselling
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Genetic operators of evolutionary algorithm in problem of collision avoidance at sea
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Chronic Rhinosinusitis—Microbiological Etiology, Potential Genetic Markers, and Diagnosis
PublikacjaChronic rhinosinusitis (CRS) is a significant public health problem. Bacterial colonization and impaired mucociliary clearance play a significant role in the inflammatory process. Several inflammatory pathways and host defense elements are altered in CRS, which may contribute to observed differences in the microbiome. To date, researching CRS has been difficult due to limited access to the studied tissue and a lack of available...
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The choice of parameters of induction motor model using a genetic algorithm.
PublikacjaRozważano problem doboru parametrów modeli matematycznych dużych 3 -fazowych silników indukcyjnych. Modele o prawidłowo dobranych parametrach mogą być pomocne podczas procedur projektowych. Podane silniki mogą być używane jako napędy sterów strumieniowych statków. Symulacje w środowisku Matlab, uwzględniają modele statyczne silników. Parametry silników dobierane są za pomocą przybornika Genetic Algorithm Toolbox. Skuteczność metody...
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New approach to railway noise modeling employing Genetic Algorithms
PublikacjaMain goal of this paper was to describe an innovative method of noise prediction based on Genetic Algorithms. First part of the paper addresses the problem of growing noise, mainly in the context of a unified method for measuring noise. Further, Genetic Algorithms are described with regards to their fundamental features. Further a description is provided as to how Genetic Algorithms were used in the area of noise modeling. Next...
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Genetic Programming with Negative Selection for Volunteer Computing System Optimization
PublikacjaVolunteer computing systems like BOINC or Comcute are strongly supported by a great number of volunteers who contribute resources of their computers via the Web. So, the high efficiency of such grid system is required, and that is why we have formulated a multi-criterion optimization problem for a volunteer grid system design. In that dilemma, both the cost of the host system and workload of a bottleneck host are minimized. On...
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Shape Optimisation of Kaplan Turbine Blades Using Genetic Algorithms
PublikacjaThis monograph is a comprehensive guide to a method of blade profile optimisation for Kaplan-type turbines. This method is based on modelling the interaction between rotor and stator blades. Additionally, the shape of the draft tube is investigated. The influence of the periodic boundary condition vs. full geometry is also discussed. Evolutionary algorithms (EA) are used as an optimisation method together with artificial neural...
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Genetic Programming for Interaction Efficient Supporting in Volunteer Computing Systems
PublikacjaVolunteer computing systems provide a middleware for interaction between project owners and great number volunteers. In this chapter, a genetic programming paradigm has been proposed to a multi-objective scheduler design for efficient using some resources of volunteer computers via the web. In a studied problem, genetic scheduler can optimize both a workload of a bottleneck computer and cost of system. Genetic programming has been...
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Genetic Positioning of Fire Stations Utilizing Grid-computing Platform
PublikacjaA chapter presents a model for determining near-optimal locations of fire stations based on topography of a given area and location of forests, rivers, lakes and other elements of the site. The model is based on principals of genetic algorithms and utilizes the power of the grid to distribute and execute in parallel most performance-demanding computations involved in the algorithm.
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Changes of emissions and atmospheric deposition of mercury, lead and cadmium
PublikacjaPrzedstawiono informacje o zmianach emisji rtęci, ołowiu i kadmu w przeszłości, jak również przedyskutowano poziom aktualnych emisji tych zanieczyszczeń oraz ich scenariusze zmian w przyszłości. Przeanalizowano wpływ różnych parametrów na zmiany emisji w tym stopień implementacji różnych strategii kontroli emisji w Europie. Scenariusze zmian emisji w przyszłości oparte są na scenariuszach rozwoju gospodarczego w poszczególnych...
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Conformational changes of peptidoglycan fragments during their interactions with vancomycin
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Changes in the Use of Agricultural Land in Poland and Czech Republic
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Command in the Police – the concept of changes in the area of formation command
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Changes in the Local Government System and Regional Policy in Poland
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Modeling changes of the ionospheric potential due to lightning and sprites
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Lubricity-based estimation of the changes in the brake fluid quality
PublikacjaW artykule przedstawiono, na podstawie wyników badań laboratoryjnych, możliwość określenia wartości smarności łączącej własności fizykochemiczne i reologiczne płynów. Smarność, która została określona dla trzech płynów hamulcowych (oznaczenia zastrzeżone przez firmę zlecającą porównanie ich własności), umożliwiła wybór najlepszego, który pewnie zostanie zastosowany w instalacjach hamulcowych samochodów.
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High pressure impact on changes in potato starch granules
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Price Changes in Wholesale Market of Electrical Energy in Poland
PublikacjaThe article discusses the Price changes on the wholesale electricity market in Poland Moreover, The price levels on the futures electricity markets and the spot transactions market are presented. The impact of emission charges under the EU ETS on the price of electricity in the domestic market has been taken into consideration Furthermore, the basic determinants of the generation structure in Poland that influence the level of...
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Determination of Changes in Viscosity of Hydrogel Depending on Shear Rates
PublikacjaThe datasets entitled Determination of changes in viscosity of hydrogel depending on shear rate contain the results of viscosity measurements using a Brookfield viscometer, with different kinds of spindles and shear rates. The data allowed the used hydrogel preparations to be characterised and their functional parameters, as substances modifying the rheology of thickeners and determining the effect of shear rate on the viscosity...
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Changes of Conformation in Albumin with Temperature by Molecular Dynamics Simulations
PublikacjaThis work presents the analysis of the conformation of albumin in the temperature range of 300K – 312K, i.e., in the physiological range. Using molecular dynamics simulations, we calculate values of the backbone and dihedral angles for this molecule. We analyze the global dynamic properties of albumin treated as a chain. In this range of temperature, we study parameters of the molecule and the conformational entropy derived from...
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Spatial sensitivity to the conductivity changes of a four electrode probe.
PublikacjaW artykule rozważana jest czułość przestrzenna, czteropunktowej, liniowej sondy na zmiany przewodności zachodzące w badanym materiale. Otrzymane wyniki wskazują, że czułość może być zarówno dodatnia i ujemna, tzn. wzrost przewodności może prowadzić zarówno do wzrostu lub do spadku mierzonej impedancji. W artykule rozważane są materiały zarówno izotropowe jak i anizotropowe. Uzyskane wyniki pozwalają wyjaśnić dlaczego niektóre...
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Anthropogenic changes of groundwater quality on the "Czarny Dwór" intake.
PublikacjaW wyniku intensywnej i trwającej 40 lat eksploatacji oraz sposobu zagospodarowania terenu nastąpiła niekorzystna zmiana jakości wód czwartorzędowego piętra wodonośnego na ujęciu "Czarny Dwór". Pojawiły się wysokie stężenia chlorków, siarczanów, azotu amonowego oraz podwyższona twardość ogólna. Badania geofizyczne wykonane w ramach współpracy Polsko - Szwedzkiej wykluczyły istnienie obecnie intruzji wód morskich.
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Sesonal changes of contamination removal in constructed wetlands system.
PublikacjaBadania prowadzona w dwch oczyszczalniach hydrofitowych zasilanych ściakami bytowo-gospodarczymi.Analizowany okres pomiarowy podzielono na sezon wegetacyjny (od kwietnia do października) oraz poza wegetacyjny (pozostałe miesiące).Uzyskane rezutlaty pozwoliły na oceną skuteczności usuwania zanieczyszczeń oraz wyznaczenie szybkości usuawania zanieczyszczeń w obu analizowanych okresach.
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GROWTH AND STRUCTURAL CHANGES IN TRANSITION COUNTRIES: THE CHICKEN OR THE EGG?
PublikacjaThe objective of this study is to test empirically the relationship between structural changes (changes in gross value added and employment) and economic growth. We used a panel Granger-causality analysis based on annual data for eight transition countries, covering the period 1995–2011. The main finding is that the causality relations analysed are heterogeneous processes and are identified more often...
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Photonic sensor to detect rapid changes in CRP levels
PublikacjaOne of the most important biomarkers used to determine inflammation is C-reactive protein (CRP). Its level, when it is within the range that does not define inflammation, informs about the risk of cardiovascular events. If the norm is exceeded and inflammation is detected in the body, CRP level can increase 1000 times within a few hours. The type of infection can also be determined based on the level of elevated CRP. All this makes...
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Structural changes in the polish economy- the analysis of input-output
Publikacjathis paper analyses the structure of polish economy using three input-output tables for years 1995, 2000 and 2004. applying the traditional methods proposed by rasmussen the sector's backward and forward linkages are identified. industries with large backward and forward linkages are named "key sectors" and play an important role in the development strategy of a country, so the outcome of the paper may be used for the development...
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Methodology of assessing the effectiveness of changes in the planning and control process
PublikacjaNiniejsze opracowanie poświęcone jest problematyce oceny efektywności zmian procesu planowania i sterowania. Jego celem jest opracowanie modelu i scharakteryzowanie sposobu oceny efektywności zmian tego procesu w odniesieniu do jej elementów składowych, jakimi są korzystność, skuteczność i ekonomiczność.
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Impact of Demographic Changes onto National Economy Development
PublikacjaThe effects of population decline and their influence onto the national economy need to be analyzed with reference to modern demographic trends regarding society ageing process. The problem of demographic changes does not only concern the birth rate, life span and migration, but it also refers to economic phenomena and thus, the economic and demographic trend interrelation becomes quite obvious. Macroeconomic approach defines the...
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Application of the F-statistic of the Fisher-Snedecor distribution to analyze the significance of the effect of changes in the compression ratio of a diesel engine on the value of the specific enthalpy of the exhaust gas flow
PublikacjaThe paper discusses the impact of changes in the compression ratio on the operating parameters of a diesel engine, e.g. on the temperature of exhaust gases. It presents the construction of the laboratory test stand, on which experimental measurements were realized. It is characterized how the actual changes of the compression ratio were introduced to the existing engine. The program of experimental investigations taking into account...
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Magnetic field microsensor based on GaAs MESFET
PublikacjaA novel concept of the drain separation design in a horizontally-split-drain GaAs MAGFET sensor, based on epitaxial layer growth, was developed. Proper choice of GaAs/AlAs/GaAs epitaxial layer sequence provided good electrical isolation between the drain regions. The measured leakage current between the drain regions was in the range of nA for up to 2V drain voltage bias difference. Performed analytical and numerical calculations...
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Pharmacokinetics and Pharmacodynamics of a Chimeric/Humanized Anti-CD3 Monoclonal Antibody, Otelixizumab (TRX4), in Subjects With Psoriasis and With Type 1 Diabetes Mellitus
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Influence of narrowband ultraviolet B phototherapy on serum tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in patients with psoriasis
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Nuclear retention of pre-mRNA involving Cajal bodies during meiotic prophase in plants
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Pathophysiological Alterations of Redox Signaling and Endocannabinoid System in Granulocytes and Plasma of Psoriatic Patients
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