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Wyniki wyszukiwania dla: MAXXI ROME
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Effects of some antibiotics on glucose 6-phosphate dehydrogenase in sheep liver
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Optimal Shape Refurbishment of Distorted Dome Structure with Safeguarding of Member Stress
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma-Recent Findings and Review
PublikacjaThe inflammatory process plays a significant role in the development of colon cancer (CRC). Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation but also impact carcinogenesis at all stages of the disease. Recent studies suggest that inflammation is of greater importance in the serrated pathway than in the adenoma-carcinoma pathway. Interleukins have gained the most attention due to their...
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma—Recent Findings and Review
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The role of genetic factors and monocyte-to-osteoclast differentiation in the pathogenesis of Charcot neuroarthropathy
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The Role of Crypto Trading in the Economy, Renewable Energy Consumption and Ecological Degradation
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Waste Fires in Poland and Some of their Environmental Implications: A Ten-Year Perspective
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The role of intermolecular interactions in stabilizing the structure of the nematic twist-bend phase
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Some aspects of vibration control. Part II: An optimal active controller.
PublikacjaPrzedstawiono teoretyczną metodę optymalnego, z punktu widzenia przyjętego wskaźnika jakości, oddziaływania na drgania liniowego układu mechanicznego. Metoda ta może być stosowana do zmniejszenia drgań układów wirujących, np. drgań okrętowych układów napędowych z silnikami tłokowymi czy drgań wirników turbinowych wywołanych biciem filmu olejowego lub siłami aerodynamicznymi.
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Influence of heat transformations on microstructure and properties of some wrought aluminium alloys.
PublikacjaOmówiono wpływ spawania na podatność do korozji naprężeniowej stopów Al-Mg i Al-Zn-Mg stwierdzając, że wzrost zawartości cynku wywołuje wzrost właściwości mechanicznych i spadek odporności na korozję naprężeniową. Wykazano, że obróbka cieplna złożona z retrogresji i powtórnego starzenia w przypadku stopów Al-Zn-Mg nie powoduje szczególnych zmian odporności na korozję naprężeniową, co pozostaje w związku z niewielką zmianą struktur...
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SimMechanics package - some effective tool for pedagogical exercises in multibody dynamics.
PublikacjaW pracy skoncentrowano się na poszukiwaniach narzędzia przydatnego w procesie nauczania dynamiki układów wielomasowch. Proces ten, z natury dwuetapowy, wymaga aby klasyczne wykłady dla studentów poszerzyć o ćwiczenia komputerowe, pozwalające na samodzielne modelowanie wybranych układów. Wymaga to zastosowania oprogramowania łatwego do nauki i wykorzystania, w tym pozwalającego na szybkie modelowanie prostych mechanizmów i umożliwiającego...
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Some remarks about numerical conditioning of discrete time Riccati eqations.
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Structural and electronic properties of some intriguing (rare-earth)Ba2Cu3O7 compounds.
PublikacjaW rozdziale przedstawiono przegląd wyników eksperymentalnych i teoretycznych dotyczących wybranych związków o wzorze (lantanowiec)Ba2Cu3O7 wykazujących całkowicie odmienne właściwości w porównaniu z całą klasą nadprzewodzących związków tlenkowych o stechiometrii 1:2:3. Szczególny nacisk położono na analizę procesu wzrostu kryształów i powstawania defektów punktowych determinujących późniejsze własności fizyczne tych materiałów....
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Some aspects of vibration control. Part I: Active and passive correction.
PublikacjaPrzedstawiono ogólne podejście do modyfikacji układu mechanicznego w ruchu harmonicznym przy użyciu aktywnych i pasywnych metod. Zaproponowano metodę wyznaczania elementów macierzy układu lub struktury i nastaw regulatora, zapewniającą najefektywniejsze oddziaływanie na dynamikę ruchu.
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Study on the role of podoplanin in papillary thyroid carcinoma using rna sequencing
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The Role of University in the Development of Entrepreneurial Intentions of Younger Generations: Selected Models
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On the role of classical and novel forms of vitamin D in melanoma progression and management
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How glycosylation affects glycosylation: the role of N-glycans in glycosyltransferase activity
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The role of the enzymatic antioxidant system in cylindrospermopsin-induced toxicity in human lymphocytes
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Some remarks on the significance of paradox for science in the context of photometric paradox case
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Some accelerationist remarks on Marcuse’s drives theory and his dialectics of civilization
PublikacjaMarcuse’s theory of civilization offers a promising Freud-Marx synthesis. His approach, best articulated in Eros and Civilization, aims at a thorough reformulation of the Freudian drive doctrine to render it more historical and concatenate it to the problem of structural violence and the institutionalized (and internalized) mechanism of repression. I claim that the said reformulation provides a cornerstone for Marcuse’s highly...
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Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9
PublikacjaAt the core of the CRISPR–Cas9 genome-editing technology, the endonuclease Cas9 introduces site-specific breaks in DNA. However, precise mechanistic information to ameliorate Cas9 function is still missing. Here, multimicrosecond molecular dynamics, free energy and multiscale simulations are combined with solution NMR and DNA cleavage experiments to resolve the catalytic mechanism of target DNA cleavage. We show that the conformation...
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Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents
PublikacjaThe group of new amide derivatives of mycophenolic acid (MPA) and selected heterocyclic amines was synthesised as potential immunosuppressive agents functioning as inosine-5'-monophosphate dehydrogenase (IMPDH) uncompetitive inhibitors. The synthesis employed uronium-type activating system (TBTU/HOBt/DIPEA) while or phosphonic acid anhydride method (T3P/Py) facilitating amides to be obtained in moderate to excellent yields without...
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The role of resilience in explaining hotel growth: A fuzzy-set QCA approach
PublikacjaPurpose: Due to the detrimental effects of the recent pandemic on the hotel sector, hotel resilience research and its impact on hotel recovery have received lots of academic attention. However, a sustainable perspective on hotel resilience, as an approach for investigating its impact on long-term hotel growth, has been largely overlooked in the hospitality resilience literature. Therefore, this paper aims to address the research...
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Some remarks on gas chromatographic challenges in the context of green analytical chemistry
PublikacjaOmówiono możliwości wprowadzenia zasad zielonej chemii analitycznej w odniesieniu do technik chromatograficznych.
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Employment and export specialisation along the development path: some robust evidence
PublikacjaThis paper contributes to the literature on the evolution of overall specialisation along the process of economic development by simultaneously estimating 'specialisation curves' emerging from fully comparable employment and export statistics in a sample of 32 economies (1980-2000). We apply semiparametric estimation methods, which allow us to combine the flexibility of the estimation with the inclusion of country-specific effects,...
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Efficient list cost coloring of vertices and/or edges of some sparse graphs
PublikacjaRozważane jest kolorowanie wierzchołków i krawędzi grafów w modelach klasycznym, totalnym i pseudototalnym z uwzględnieniem dodatkowego ograniczenia w postaci list dostępnych kolorów. Proponujemy wielomianowy algorytm oparty na paradygmacie programowania dynamicznego dla grafów o strukturze drzewa. Wynik ten można uogólnić na grafy o liczbie cyklomatycznej ograniczonej z góry przez dowolnie wybraną stała.
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Cellular senescence induced by DNA damage and its role in carcinogenesis and chemotherapy
PublikacjaUszkodzenia DNA indukują w komórce różne procesy, w tym starzenie komórkowe, co może uruchamiać proces karcinogenezy jak i być związane z odpowiedzią na leki przecinowotworowe. Biologiczna rola starzenia komórkowego nie jest jednak jasna. Zasugerowano, że proces starzenia komórkowego może hamować proces karcinogenezy poprzez indukcję nieodwracalnego zahamowania wzrostu przez czynniki genotoksyczne. Indukcja starzenia komórkowego...
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Some remarks on problem of site characterisation - a subjective experience on theory and practice
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublikacjaDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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The role of SSVF and SSHF beds in concentrated wastewater treatment, design recommendation
PublikacjaThe return flows of reject water from sewage sludge dewatering alter the activated sludge process ina conventional WWTP and increase TN concentration in the final effluent from WWTP. The objectiveof the investigation carried out was to consider the application of multistage treatment wetland(MTW) for the treatment of reject water from sewage sludge dewatering in a centrifuge (RWC). Thispaper aims to present the design and performance...
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On some aspects of torsional buckling of thin-walled I-beam columns
PublikacjaW pracy podsumowano wyniki badań zjawiska wyboczenia skrętnego prętów o przekroju dwuteowym. Zbadano wpływ początkowego wygięcia giętnego na wartość siły krytycznej wyboczenia skrętnego. Z zasady stacjonarności energii potencjalnej wyprowadzono równania różniczkowe wyboczenia skrętnego. Wartość siły krytycznej wyznaczono stosując podejście perturbacyjne. Wyniki analityczne porównano z rezultatami otrzymanymi za pomocą 6-parametrowej...
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On some properties of 2d spectral finite elements in problems of wave propagation
PublikacjaW pracy przedstawiono sformułowanie dwuwymiarowych elementów spektralnych stosowanych w symulacji propagacji fal prowadzonych. Zbadano własności tych elementów pod kątem występowania form pasożytniczych, odporności na dystorsję siatki oraz zbadano wpływ kształtu elementu na krzywe dyspersji
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Retention behaviour of some high-intensity sweeteners on different SPE sorbents
PublikacjaThe objective of this paper is to provide information about application of solid phase extraction (SPE) for isolation of nine high-intensity sweeteners (acesulfame-K, alitame, aspartame, cyclamate, dulcin, neotame, saccharin, sucralose and neohesperidin dihydrochalcone) from aqueous solutions. The influence of several types of LC-MS compatible buffers (different pH values and compositions) on their recovery has been studied and...
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The role of SSVF and SSHF beds in concentrated wastewater treatment, design recommendation
PublikacjaThe return flows of reject water from sewage sludge dewatering alter the activated sludgeprocess in a conventional WWTP and increas TN concentration in final effluent from WWTPs.The objectives of the investigation carried out is to consider the application of sequential SS VFbeds and an SS HF bed for the treatment of highly polluted wastewater, namely reject waterfrom sewage sludge dewatering in a centrifuge (RWC). This paper aims...
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Innovation and Knowledge Management in the SME Sector and the Role of Normative Management Systems
PublikacjaThe article presents deliberations related to importance and specificity of innovation activities in small and medium-sized enterprises. Basing on results of the research the characteristics of the SMEs concerning process related and organizational innovation has been determined. Interrelations between innovation activities and knowledge management within the framework of normative management systems have been emphasized.
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The role of the sawage treatment plant in the removal of genotoxic compounds from the environment
PublikacjaOne reason for increased incidence of various types of cancer are environmental pollutants particularly of anthropogenic origin. All human activities may pollute the environment, but some have significant impact, just to mention energy industry, mining, transportation, chemical and petrochemical industries and housing. Environmental pollutants are a large group of compounds in terms of their physicochemical properties, some of...
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Self-refraction of acoustic pulses with shock fronts in some nonequilibrium media
PublikacjaThe nonlinear self-refraction of acoustic pulsed beams, which include shock fronts, is studied. The medium of sound propagation is a gas where thermodynamically nonequilibrium processes take place, such as exothermic chemical reaction or excitation of vibrational degrees of a molecule’s freedom. Comparative analysis of the features of sound propagation over gases where pure nonlinear attenuation of the shock wave occurs, and gases...
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Online stores' credibility: the moderating role of customers' gender and self-efficacy
PublikacjaThe evaluation of online stores’ credibility by customers in regard of gender and self-efficacy is presented. Two groups of attributes, usability and informational content, were characteristics of credibility. The survey involved students as representatives of the largest group of the Internet users. As shown by the results obtained, the informational content of online stores (such as recommendations) and its professionalism was...
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Knowledge‐Intensive Business Services (KIBS) and Their Role in the Knowledge‐Based Economy
PublikacjaThe importance of the knowledge‐intensive business services sector for the development of the economy is growing. In the 80s and 90s this sector became the fastest growing sector in the OECD countries (OECD, 2001). Many publications stress its close relationship to the levels of innovation and performance of the whole economy (e.g. Hipp, 1999; Tomlinson, 1999; Aslesen and Isaksen, 2007). It is an increasingly common belief that...
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Fem analysis of cosserat plates and shells based on some constitutive relations
PublikacjaPrzeprowadzono studium doboru mikropolarnych współczynników konstytutywnych w pewnym modelu płyty Cosseratów. Wyznaczono ograniczenia na ich wartości i przeprowadzono parametryczną analizę wpływu tych współczynników na geometrycznie nieliniowe deformacje powłok z ortogonalnymi przecięciami płatów.
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SAWING PROCESS AS A NEW ALTERNATIVE WAY OF DETERMINING SOME WOOD PROPERTIES
PublikacjaCutting forces (power) could be considered from a point of view of modern fracture mechanics. The developed cutting model, derived from fracture mechanics, includes work of separation (fracture toughness) in addition to plasticity and friction, and also dullness of the cutting edge described by the cutting edge radius. Moreover, forecasting of the shear plane angle for the cutting models, broaden possibilities of energetic effects...
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Magnetizabilities of relativistic hydrogenlike atoms in some arbitrary discrete energy eigenstates
PublikacjaWe present the results of numerical calculations of magnetizability of the relativistic hydrogenlike atoms. Exploiting the analytical formula for $\chi$ we have found the values of the magnetizability for the ground state and for the first and the second set of excited states of the atom. The results for ions with the atomic number $0
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The role of heterotrophic plate count bacteria in bottled water quality assessment
PublikacjaThe ever-growing popularity of bottled water is the result of many factors. One of the most relevant is the widespread belief that bottled water is safer for drinking than tap water. In fact many literature sources describe the rapid growth of the amounts of microorganisms in bottled water samples following the bottling process. The main purpose of this article is to collect the information on the factors which may affect this...
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Interaction of human serum albumin with volatiles and polyphenols from some berries
PublikacjaHeadspace solid-phase microextraction coupled with comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (HS-SPME/GC GCeTOFMS) identified 19 and quantified 6 monoterpenes in gooseberries, blueberries and cranberries. As a protein model human serum albumin (HSA) was used in interaction with terpenes. Specific binding of terpenes to HSA under the physiological conditions was a result of the formation...
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Role of surface recombination in perovskite solar cells at the interface of HTL/CH3NH3PbI3
PublikacjaIn order to achieve the highest performance of organometal trihalide perovskite solar cells, it is required to recognize the dominant mechanisms which play a key role in a perovskite material. In the following studies, we have focused on the interfacial recombination between the hole transporting layer (HTL) and the perovskite CH3NH3PbI3 in solar cell devices with p–i–n architecture. It has been shown that Cu:NiOx : used as HTL...
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Determination of the Bending Properties of Wire Rope Used in Cable Barrier Systems
PublikacjaThis paper presents research on the bending properties of 3 × 7 19-mm wire rope commonly used in road cable barriers. A total of 19 experimental tests were conducted. In addition, two nonlinear 3D numerical models of the wire rope using beam and solid finite elements were developed. Based on these models, four numerical simulations were carried out. The numerical results were validated against the experimental ones and a very good...
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Precipitation and Transformation of Vaterite Calcium Carbonate in the Presence of Some Organic Solvents
PublikacjaIn this paper, the production of CaCO3 particles via the carbonation route in the reaction of CaCl2 and CO2, using NH3 as a promoter of CO2 absorption, was studied. The solvents used as the reaction media for CaCO3 precipitation were aqueous solutions of methanol, isopropanol and dimethyl sulfoxide (DMSO), in a concentration range of 0–20% (v/v). It was found that the presence of an organic additive influenced the precipitation...
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The role of low-energy electrons in the charging process of LISA test masses
PublikacjaThe estimate of the total electron yield is fundamental for our understanding of the test-mass charging associated with cosmic rays in the Laser Interferometer Space Antenna (LISA) Pathfinder mission and in the forthcoming gravitational wave observatory LISA. To unveil the role of low energy electrons in this process owing to galactic and solar energetic particle events, in this work we study the interaction of keV and sub-keV...
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The role of governance to support smart community development: a systematic literature review
PublikacjaThis paper studies the interaction between the smart community and smart governance concepts to elaborate on the role of governance to support local governments in developing smart communities’ strategies and solutions. We perform a systematic literature review to analyse how the concept of smart community has advanced in terms of its definitions, context, benefits, challenges, and enablers and propose a unified term with a focus...