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Search results for: E COLI INACTIVATION
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Elimination of wild-type P53 mRNA in glioblastomas showing heterozygous mutations of P53
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Biological and antibacterial properties of chitosan-based coatings with AgNPs and CuNPs obtained on oxidized Ti13Zr13Nb titanium alloy
PublicationDespite numerous studies, the antibacterial efficiency and cytotoxicity of chitosan-based coatings with nanometals need further studies. The purpose of this research was to determine the biological properties of chitosan coatings implemented with either silver nanoparticles (AgNPs) or copper nanoparticles (CuNPs), that were electrophoretically deposited on electrochemically oxidized Ti13Zr13Nb alloy. The SEM tests were used to...
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Elektryczne promy morskie na przykładzie Norwegii
PublicationNorwegia jest światowym liderem wdrażania rozwiązań z zakresu e-mobilności (elektromobilności). W 2018 roku odbyła się ekspedy-cja naukowa projektu ELMAR w norweskich fiordach, podczas której zwizytowano wybrane promy pasażerskie oraz pasażersko-samochodowe. Zebrane przez autorów doświadczenia zostały przedstawione w artykule.
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Quantum chemical modeling (DFT) of active species on the VWO catalyst surface in various redox conditions
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The role of tungsten in formation of active sites for no SCR on the V-W-O catalyst surface — quantum chemical modeling (DFT)
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Characterization of carbon deposit with controlled carburization degree
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Systematic study on synthesis and purification of double-walled carbon nanotubes synthesized via CVD
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Technika wyłączania, zmniejszająca skutki zwarć łukowych. - Tł. z Plant Engineering, March 2007. - Tyt. oryg.: Circuit breaker technology reduces arc flash risk / Patricia E. Chandler
PublicationW artykule podano sposoby zmniejszania skutków zwarć łukowych oraz opisano zalety nowoczesnych wyłączników ograniczających prądy zwarciowe. Podano możliwości układów elektronicznych w monitorowaniu parametrów elektrycznych instalacji, stanu pracy wyłączników i wykrywaniu zwarć.
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In the search for experimental and quantumchemical evidence for zwitterionic nature of (2 E )-3-[4-(dimethylamino)phenyl]-2-nitroprop-2-enenitrile – An extreme example of donor–π–acceptor push–pull molecule
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An experimental and theoretical study of the hetero Diels–Alder reactions between (E)-2-aryl-1-cyano-1-nitroethenes and ethyl vinyl ether: one-step or zwitterionic, two-step mechanism?
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Dicyclohexylammonium benzenethiolate. Acta Cryst. Sect. E Struct. Rep. [on-line]**2003 vol. 59 s. o765-o766, 2 rys. 2 tab. bibliogr. 11 poz. tiofenolan dicykloheksyloamoniowy.
PublicationZwiązek o wzorze C12H24N+ x C6H5S- został otrzymany poprzez reakcję tiofeno-lu z dicykloheksyloaminą. Oba fragmenty jonowe powiązane są w długie łańcu-chy poprzez wiązania N-H...S. Strukturę cząsteczkową i krystaliczną wyzna-czono posługując się rentgenowską analizą strukturalną.
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F05 Nine Hole Peg Test As A Measure Of Visuomotor Coordination In Huntington's Disease
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Optical method supported by machine learning for urinary tract infection detection and urosepsis risk assessment
PublicationThe study presents an optical method supported by machine learning for discriminating urinary tract infections from an infection capable of causing urosepsis. The method comprises spectra of spectroscopy measurement of artificial urine samples with bacteria from solid cultures of clinical E. coli strains. To provide a reliable classification of results assistance of 27 algorithms was tested. We proved that is possible to obtain...
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Antimicrobial resistance of fecal indicators in muncipal wastewater treatment plant
PublicationAntimicrobial resistance of fecal coliforms (n = 153) and enterococci (n = 199) isolates was investigated in municipal wastewater treatment plant (WWTP) based on activated sludge system. The number of fecal indicators (in influent and effluent as well as in the aeration chamber and in return activated sludge mixture) was determined using selective media. Susceptibility of selected strains was tested against 19 (aminoglycosides,...
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Higher Responsiveness to Rosuvastatin in Polygenic versus Monogenic Hypercholesterolemia: A Propensity Score Analysis
PublicationBackground: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C). We sought to investigate whether the underlying monogenic or polygenic defect is associated with the response to rosuvastatin. Methods: FH Individuals were tested for mutations in LDLR and APOB genes. A previously established LDL-C-specific...
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Awareness of Influenza and Attitude Toward Influenza Vaccination Among Medical Students
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Analiza symulacyjna wybranych algorytmów dostarczania paczek wiadomości w sieci DTN na Bałtyku
PublicationJedną z dróg zwiększania bezpieczeństwa żeglugi morskiej jest zapewnienie powszechnej dostępności usług e-nawigacji na obszarach morskich pozbawionych dostępu do Internetu. W artykule opisano wyniki symulacji wybranych algorytmów przekazywania wiadomości usług niewrażliwych na opóźnienia w znacznej odległości od lądu, w sieci o nieciągłej i sporadycznej łączności.
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Electrical Simulations of the SIS100 Superconducting Dipole and Quadrupole Circuits: Transients, Earthing and Failure Modes
PublicationThe 100 Tm superconducting synchrotron SIS100 is the main accelerator of the international Facility for Antiproton and Ion Research (FAIR) currently under advanced construction in Darmstadt, Germany. The SIS100 dipole circuit which creates the magnetic field required to bend the beam, consists of 108 dipoles distributed over six arc sections of the ring. The magnetic field for the beam focusing is generated by three individual...
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Investigation of corrosion behavior of 6060 and 6082 aluminum alloys under simulated acid rain conditions
PublicationInstantaneous impedance changes of 6060 and 6082 type aluminum alloys in pure water, and simulated acid rain poured into the pure water was investigated by dynamic electrochemical impedance spectroscopy (DEIS). In this way, the influence of aluminum content on the corrosion behavior of 6060 and 6082 type aluminum alloys immersed in simulated acid rain was determined. The corrosion rate of the alloy decreased with increasing Al...
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Pressure-induced phase transitions in LnTe (Ln=La, Gd, Ho, Yb) and AmTe
PublicationThe structural behaviour under compression of different lanthanide (La, Gd, Ho, Yb) and actinide (Am) monochalcogenides is studied by means of in situ high-pressure x-ray diffraction. All the investigated compounds crystallize at ambient conditions within a cubic (B1) NaCl-type structure but show different behaviours at high pressures. LaTe and AmTe undergo B1 to B2 (CsCl-type structure) phase transitions, starting at 9 GPa and...
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Ammonolysis of (3-chloropropyl)trimethoxysilane
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Multichannel taste sensors with lipid, lipid like – polymer membranes
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Conformational Studies of Two Bradykinin Antagonists by Using Two-dimensional NMR Techniques and Molecular Dynamics Simulations
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Cis/trans conformational equilibrium across the N-methylphenylalanine2- N-methylphenylalanine3 peptide bond of arginine vasopressin analogs
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Lamb wave propagation in a single lap adhesive joint
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Studies on the bioactive properties of Penicillium mallochi ARA-1 pigment isolated from coffee plantation
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Reliability analysis of aerodrome’s electronic security systems taking into account electromagnetic interferences
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Effect of sugar concentration on ginsenoside biosynthesis in hairy root cultures of Panax quinquefolium cultivated in shake flasks and nutrient sprinkle bioreactor
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Catalytic topoisomerase II inhibitors in cancer therapy.
PublicationDNA topoizomeraza II jest jednym z głównych celów molekularnych dla leków stosowanych w terapii przeciwnowotworowej. Wszystkie inhibitory tego enzymu są zdolne do zakłócania w jeden z etapów cyklu katalitycznego topoizomerazy II. Związki, które stabilizują kowalencyjny kompleks DNa i topoizomerazy II (znany jako kompleks rozszczepialny) są nazywane truciznami topoizomerazy, inne związki, które hamują aktywność enzymu na innych...
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From DNA damage to G2 arrest: the many roles of topoisomerase II. W: Prog-ress in Cell Cycle Research. Ed. Meijer L., Jezequel A., Roberge M. London: Plenum Publ. Comp. Ltd**2003 vol. 5 chapt. 30 s. 295-300 Od uszkodzeń DNA do bloku w G2: wiele ról dla topoizomerazy II.
PublicationInhibitory DNA topoizomerazy II sa jednymi z najbardziej szeroko stosowanymi lekami przeciwnowotworowymi. Związki te indukuja pekniecia nici DNA i bloku progresji cyklu komorkowego w fazie G2. Jednak topoizomeraza II jest nie tylko celem molekularnym dla lekow przeciwnowtworowych ale enzym ten pelniwazna role w odpowiedzi komorkowej na dzialanie wielu lekow uszkadzajacych DNA. Topoizomeraza tworzy kompleksy molekularne z bialkami...
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Synthesis and characterization of novel renewable polyesters based on 2,5-furandicarboxylic acid and 2,3-butanediol
PublicationNovel polyesters from 2,5-furandicarboxylic acid or 2,5-dimethyl-furandicarboxylate and 2,3-butanediol have been synthesized via bulk polycondensation catalyzed by titanium (IV) n-butoxide, tin (IV) ethylhexanoate, or zirconium (IV) butoxide. The polymers were analyzed by size exclusion chromatography, nuclear magnetic resonance spectroscopy, Fourier transform infrared spectroscopy (FTIR), matrix-assisted laser ionization-desorption...
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Photocatalytic hydrogen generation over alkaline-earth titanates in the presence of electron donors
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918 The role of patients and doctors in making decisions about the choice of the kind of adjuvant treatment in early breast cancer
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Potential allosteric modulators of the proteasome activity
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Influence of synthesis conditions on glass formation, structure and thermal properties in the Na 2 O-CaO-P 2 O 5 system doped with Si 3 N 4 and Mg
PublicationOxynitride phosphate glasses and glass-ceramics were prepared using new synthesis routes for phosphate glasses. Materials were melted from pre-prepared glass samples in the system Na-Ca-P-O with addition of Mg and/or Si3N4 powders under different preparation conditions. The melting process was conducted at 1000–1500 °C either under air or nitrogen atmosphere to obtain materials with different nitrogen content. Their topography...
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Effect of high pressure and sub-zero temperature on some gram-negative bacteria.
PublicationCelem pracy było określenie przeżywalności wybranych gramujemnych bakterii na działanie wysokiego ciśnienia i ujemnej temperatury. Traktowanie komórek bakterii ciśnieniem 193 MPa w temperaturze -20C przez 24 godziny, powodowało całkowitą inaktywację bakterii E. coli, P. fluorescens i T. thermophilus. Po działaniu ciśnienia przez krótszy czas występowały różnice we wrażliwości między badanymi szczepami. Najmniej odporny na działanie...
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Clinical characteristics of patients with resistant hypertension: the RESIST-POL study
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As causas do trincamento a frio de um ação submetido a soldagem subaquática
PublicationA soldagem subaquàtica usada na confeccao de juntas de acos de alta resistencia aumenta a sua susceptibilidade ao trincamento a frio, um efeito decorrente da transferencia de calor muito mais rapida a partir da area de soldagem e da presenca de hidrogenio difusivel, o que causa aumento da fragilidade do metal. Este trabalho avalia esta propensao ao trincamento a frio do aco S355G10+N usado na construcao de estrururas hidrotecnicas...
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Photoinactivation of Staphylococcus aureus using protoporphyrin IX: the role of haem-regulated transporter HrtA
PublicationLight- and photosensitiser-based antimicrobial photodynamic therapy is a very promising approach to the control of microbial infections. How the phenotypic features of a microorganism affect its response to photosensitiser-based photokilling represents an area of substantial research interest. To understand the mechanisms governing the phenomenon of a strain-dependent response to photodynamic inactivation (PDI), we analysed the...
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Imidazoacridinone antitumor agent C-1311 as a selective mechanism- based inactivator of human cytochrome P450 1A2 and 3A4 isoenzymes.
Publication5-Diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311), a promising antitumor agent that is also active against autoimmune diseases, was determined to be a selective inhibitor of the cytochrome P450 (CYP) 1A2 and 3A4 isoenzymes. Therefore, C-1311 might modulate the effectiveness of other drugs used in multidrug therapy. The present work aimed to identify the mechanism of the observed C-1311-mediated inactivation of CYP1A2...
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Construction and purification of his6-Thermus thermophilus MutS protein.
PublicationGen mutS z termofilnej bakterii Thermus thermophilus zamplifikowano przy użyciu PCR, sklonowano i przeprowadzono jego ekspresję w E. coli. Rekombinantowe białko MutS zawierające oligohistydynową domenę na N-końcu oczyszczono w jednoetapowej procedurze przy wykorzystaniu chromatografii powinowactwaNi(2+). Zdolność do rozpoznania niekomplementarności białka his(6)-MutS potwierdzono w eksperymentach ochrony DNA przed trawieniem...
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Direct cloning of heavy metal resistance genes from metagenomic DNA
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Urinary tract infection in children: Diagnosis, treatment, imaging – Comparison of current guidelines
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Advances in engineering of diameter and distribution of the number of walls of carbon nanotubes in alcohol CVD
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Empirical analysis of tree-based classification models for customer churn prediction
PublicationCustomer churn is a vital and reoccurring problem facing most business industries, particularly the telecommunications industry. Considering the fierce competition among telecommunications firms and the high expenses of attracting and gaining new subscribers, keeping existing loyal subscribers becomes crucial. Early prediction of disgruntled subscribers can assist telecommunications firms in identifying the reasons for churn and...
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Triplet–Triplet Annihilation Upconverting Liposomes: Mechanistic Insights into the Role of Membranes in Two-Dimensional TTA-UC
PublicationTriplet−triplet annihilation upconversion (TTA-UC) implemented in nanoparticle assemblies is of emerging interest in biomedical applications, including in drug delivery and imaging. As it is a bimolecular process, ensuring sufficient mobility of the sensitizer and annihilator to facilitate effective collision in the nanoparticle is key. Liposomes can provide the benefits of two-dimensional confinement and condensed concentration...
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Suppressors of lapC mutation identify new regulators of LpxC, which mediates the first committed step in lipopolysaccharide biosynthesis
PublicationGram-negative bacteria, such as Escherichia coli, are characterized by an asymmetric outer membrane (OM) with lipopolysaccharide (LPS) located in the outer leaflet and phospholipids facing the inner leaflet. E. coli recruits LPS assembly proteins LapB, LapC and LapD in concert with FtsH protease to ensure a balanced biosynthesis of LPS and phospholipids. We recently reported that bacteria either lacking the periplasmic domain of...
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“Dilute & Shoot” approach for rapid determination of trace amounts of nicotine in zero-level e-liquids by reversed phase liquid chromatography and hydrophilic interactions liquid chromatography coupled with tandem mass spectrometry-electrospray ionization
PublicationTwo analytical procedures are proposed where HILIC and RPLC techniques are coupled with tandem mass spectrometry detection for rapid determination of trace amounts of nicotine in zero-level liquids for electronic cigarettes. Samples are prepared on the basis of the approach “dilute & shoot” which makes this important step quick and not complicated. The chromatographic separation was carried out on a Zorbax XDB column (RPLC method)...
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“Dilute & Shoot” approach for rapid determination of trace amounts of nicotine in zero-level e-liquids by reversed phase liquid chromatography and hydrophilic interactions liquid chromatography coupled with tandem mass spectrometry-electrospray ionization
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Halucynacje chatbotów a prawda: główne nurty debaty i ich interpretacje
PublicationGeneratywne systemy sztucznej inteligencji (SI) są w stanie tworzyć treści medialne poprzez zastosowanie uczenia maszynowego do dużych ilości danych szkoleniowych. Te nowe dane mogą obejmować tekst (np. Bard firmy Google, LLaMa firmy Meta lub ChatGPT firmy OpenAI) oraz elementy wizualne (np. Stable Diffusion lub DALL-E OpenAI) i dźwięk (np. VALL-E firmy Micro- soft). Stopień zaawansowania tych treści może czynić je nieodróżnialnymi...