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The Influence of Cold Atmospheric Pressure Plasma-Treated Media on the Cell Viability, Motility, and Induction of Apoptosis in Human Non-Metastatic (MCF7) and Metastatic (MDA-MB-231) Breast Cancer Cell Lines
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Ewa Augustin dr hab.
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Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublicationIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
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Impedance Measurement and Selection of Electrochemical Equivalent Circuit of a Working PEM Fuel Cell Cathode
PublicationThe dynamic impedance analysis of direct methanolfuel cell (DMFC) cathode supplied with pure oxygen is pre-sented. Presented results were obtained during dynamic chang-es of the current density in working fuel cell. Investigation ofthe occurring processes at cathode was carried with dynamicelectrochemical impedance spectroscopy (DEIS). A discussionwas conducted based on the determined correlation parameterχ2. It was shown that...
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Performance of a single layer fuel cell based on a mixed proton-electron conducting composite
PublicationMany of the challenges in solid oxide fuel cell technology stem from chemical and mechanical incompatibilities between the anode, cathode and electrolyte materials. Numerous attempts have been made to identify compatible materials. Here, these challenges are circumvented by the introduction of a working single layer fuel cell, fabricated from a composite of proton conducting BaCe0.6Zr0.2Y0.2O3-δ and a mixture of semiconducting...
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Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions
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Analysis of Emission Factors in RDE Tests As Well as in NEDC and WLTC Chassis Dynamometer Tests
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Development of a compact microstrip resonant cell aimed at efficient microwave component size reduction
PublicationA comprehensive comparison of a wide collection of compact microstrip resonant cells (CMRCs) found in the extensive body of literature has been presented. The evaluation of different CMRC designs has led to the selection of the most promising CMRC geometry for the efficient miniaturisation of modern microwave components. In order to showcase the vital effectiveness of the approach, the initially selected CMRC has been notably...
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Covalent DNA modification by products of myrosinase catalysed glucosinolate degradation in cell-free system
PublicationThe bioactive phytochemicals found in Brassica vegetables belonging to glucosinolates (GLS) and especially the products of their degradation isothiocyanates (ITC) and indoles are regarded as the most promising cancer chemopreventive compounds. These secondary metabolites constitute defence system repelling or preventing the development of agrophages attacking brassica plants. The antibiological properties of these compounds suggest...
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Applications of spin coating of polymer precursor and slurrysuspensions for Solid Oxide Fuel Cell fabrication
PublicationW pracy przedstawiono możliwości zastosowania w tlenkowych ogniwach paliwowych metody nanoszenia wirowego prekursorów polimerowych i zawiesin. Przedstawiono przykłady zastosowania tej metody do wytworzenia elektrolitu oraz warstw ochronnych dla stali nierdzewnych.
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FMO1 Is Involved in Excess Light Stress-Induced Signal Transduction and Cell Death Signaling
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EDS1-Dependent Cell Death and the Antioxidant System in Arabidopsis Leaves is Deregulated by the Mammalian Bax
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Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis
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A Proliferation-Inducing Ligand and B-Cell Activating Factor Are Upregulated in Patients with Essential Thrombocythemia
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Across-shift changes in upper airways after exposure to bacterial cell wall components
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Well-Designed Porous Graphene Flakes for Lithium-Ion Batteries with Outstanding Rate Performance
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Changes in the Cell Wall Proteome of Leaves in Response to High Temperature Stress in Brachypodium distachyon
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Large-scale Rowe cell experimental study on coefficient of consolidation of coal mine tailings
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Electroporation with Cisplatin against Metastatic Pancreatic Cancer:In VitroStudy on Human Primary Cell Culture
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Structure–bioavailability relationship study of genistein derivatives with antiproliferative activity on human cancer cell
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Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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Adoptive Cell Therapy—Harnessing Antigen-Specific T Cells to Target Solid Tumours
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Serum of obstructive sleep apnea patients impairs human coronary endothelial cell migration
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Ginsenoside and phenolic compounds in hydromethanolic extracts of American ginseng cell cultures and their antioxidant properties
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On a method of modelling and simulation of vibration surveillance during ball end milling of flexible details
PublicationPraca dotyczy nadzorowania drgań podczas frezowania przedmiotów podatnych smukłym frezem kulistym, z uwzględnieniem zgodności parametrów modelu modalnego. Przeprowadzono analizę dynamiki procesu frezowania. Następnie przedstawiono analizę niestacjonarnego układu drgającego, w którym wyodrębniono podukłady: modalny, strukturalny i łączący. Do minimalizacji poziomu drgań zastosowano dopasowanie prędkości obrotowej wrzeciona do optymalnego...
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Modelling and investigation of vibration surveillance during ball end milling of curved flexible details
PublicationPraca dotyczy nadzorowania drgań podczas frezowania zakrzywionych przedmiotów podatnych smukłym frezem kulistym, z uwzględnieniem zgodności parametrów modelu modalnego. Dokonano analizy dynamiki niestacjonarnego układu drgającego, w którym wyodrębniono podukłady: modalny, strukturalny i łączący. Do minimalizacji poziomu drgań zastosowano dopasowanie prędkości obrotowej wrzeciona do optymalnego kąta przesunięcia fazowego. Zasadność...
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On a method of modelling and simulation of vibration surveillance during ball end milling of flexible details
PublicationPraca dotyczy nadzorowania drgań podczas frezowania przedmiotów podatnych smukłym frezem kulistym, z uwzględnieniem zgodności parametrów modelu modalnego. Przeprowadzono analizę dynamiki procesu frezowania. Następnie przedstawiono analizę niestacjonarnego układu drgającego, w którym wyodrębniono podukłady: modalny, strukturalny i łączący. Do minimalizacji poziomu drgań zastosowano dopasowanie prędkości obrotowej wrzeciona do optymalnego...
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QoS provisioning in a single-cell ad hoc WLAN via queuing and stochastic games
PublicationPokazano, że stosowanie agresywnych strategii dostępu do medium transmisyjnego może stanowić dla stacji sieci gwarancję równej szansy uzyskania pożądanej przepływności oraz zachowania jej na cały czas transferu danych. Przeprowadzono analizę gier typu stochastycznego pod kątem istnienia równowagi strategicznej przy założeniu probabilistycznych strategii dostępu.
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Perturbation of cellular functions by topoisomerase II inhibitors: all roads lead to cell death?
PublicationPraca przeglądowa opisuje jakie funkcje mogą ulec zahamowaniu/zmianie pod wpływem działania inhibitorów topoizomerazy typu II w komórkach nowotworowych. W szczególności dyskutujemy jakie zmiany w szlakach sygnalizacji wewnątrzkomórkowej mogą prowadzić do zahamowania wzrostu oraz indukcji różnych rodzajów śmierci komórkowej i czy rodzaj śmierci komórkowej może decydować o skuteczności leków przeciwnowotoworowych, które hamują aktywność...
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The influence of fresh cabbage and sauerkraut juices on the activity of protective enzymes in human cell lines
PublicationMechanizmami przeciwrakotwórczego działania związków zawartych w kapuście jest m.in. metaboliczna aktywacja enzymów II fazy detoksykacji, indukcja enzymów naprawczych DNA oraz aktywnośc przeciwutleniająca. Do enzymów II fazy odtruwania należą m.in. S-transferazy glutationowe (GST) oraz oksydoreduktaza chinonowa NQO1 zwana też DT-diaforazą. GST katalizują reakcję sprzęgania glutationu z wieloma różnymi typami ksenobiotyków, ułatwiając...
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Fabrication of solid oxide fuel cell supported on speciallyperformed ferrite-based perovskite cathode
PublicationW pracy przedstawiono warunki technologiczne niezbedne do wytworzenia tlenkowego ogniwa paliwowego na elencie nośnym z materiału perowskitowego LSF. Jako elektrolit stosowana była ceramika z tlenku ceru. Między innymi badany były właściwości elektryczne zarówno materiału katodowego jak i ogniwa.
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Lenalidomide in heavily pretreated refractory diffuse large B-cell lymphoma: a case report
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Comparison of two doses of intravenous temsirolimus in patients with relapsed/refractory mantle cell lymphoma
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Polish Lymphoma Research Group Experience With Bexarotene in the Treatment of Cutaneous T-Cell Lymphoma
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Simvastatin Coadministration Modulates the Electrostatically Driven Incorporation of Doxorubicin into Model Lipid and Cell Membranes
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Tool Life and Process Dynamics in High Speed Ball End Milling of Hardened Steel
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Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target
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KMgF3:Eu2+ as a new fluorescence-based pressure sensor for diamond anvil cell experiments
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The simultaneous detection of food dyes from different samples in a 96-well plate by spectrophotometry
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Primary cutaneous anaplastic large-cell lymphoma in a patient with Hodgkin’s disease – case report
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Local Ordering Changes in Pt-Co Nanocatalyst Induced by Fuel Cell Working Conditions
PublicationPraca poświęcona jest szczegółowej analizie zmian w lokalnej strukturze atomowej i elektronowej nanocząstek Pt-Co pracujących jako katalizatory w polimerowych ogniwach paliwowych wywołanych cyklicznie zmieniającymi się warunkami pracy ogniwa. Do analizy wykorzystano badania XAS realizowane ex-situ i in-situ, XRD i TEM. Analizując widma XAFS wzięto pod uwagę możliwy wpływ nieporządku chemicznego oraz redukcję liczb koordynacyjnych...
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Investigation of functional layers of solid oxide fuel cell anodes for synthetic biogas reforming
PublicationSolid oxide fuel cells (SOFCs) are one of the most promising energy conversion devices due to their high efficiency, low pollution and fuel flexibility. Unfortunately, when hydrocarbons are used as a fuel, for example in the form of a biogas, solid carbon can deposit on the anode surface. This process leads to the degradation of the fuel cell performance. A possible solution to this problem is to apply an additional catalytic material,...
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Stainless steel/yttria stabilized zirconia composite supported solid oxide fuel cell
PublicationW tym artykule opisano wytworzenie i przebadanie kompozytowych elementów nośnych tlenkowych ogniw paliwowych. Podłoża nośne zostały wytworzone ze stali nierdzewnej i tlenkiem itru stabilizowanego tlenku cyrkonu (YSZ), których proszki zmieszano w różnych proporcjach objętościowych. Zachowanie podłoży podczas spiekania (skurcz liniowy, porowatość) oraz wysokotemperaturowe właściwości (odporność na utlenianie, przewodność elektryczna)...
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EVALUATION OF SURFACE ROUGHNESS PARAMETERS OF TURNED GEAR WHEELS HOLES MACHINED BY BALL BURNISHING
PublicationW artykule zaprezentowano wyniki z badań eksperymentalnych dotyczących przygotowania powierzchni do obróbki wykończeniowej nagniataniem. Badania dotyczyły obróbki materiałów w stanie utwardzonym po hartowaniu. analizowano wpływ parametrów toczenia na twardo na uzyskiwane wartości parametrów chropowatości powierzchni jako wejściowych przed procesem nagniatania.
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Magnetic field effects in dye-sensitized solar cells controlled by different cell architecture
PublicationThe charge recombination and exciton dissociation are generally recognized as the basic electronic processes limiting the efficiency of photovoltaic devices. In this work, we propose a detailed mechanism of photocurrent generation in dye-sensitized solar cells (DSSCs) examined by magnetic field effect (MFE) technique. Here we demonstrate that the magnitude of the MFE on photocurrent in DSSCs can be controlled by the radius and...
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Induced-fit binding of laccase to gold and carbon electrodes for the biological fuel cell applications
PublicationAnalogues of laccase natural substrates (syringic, veratric, ferulic, vanillic, isovanillic, 3,5-dimethoxybenzoic aldehydes) were employed to bind and orient laccase molecules in a way which facilitates adsorption of the catalyst molecules and their electrical connection with the conductive support. Laccase was bound efficiently to these substrates both on gold and carbon electrodes forming, respectively, 2D and 3D films sensitive...
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Influence of algorithmic management practices on workplace well-being – evidence from European organisations
PublicationPurpose Existing literature on algorithmic management practices –defined as autonomous data-driven decision making in people's management by adoption of self-learning algorithms and artificial intelligence – suggests complex relationships with employees' well-being in the workplace. While the use of algorithms can have positive impacts on people-related decisions, they may also adversely influence job autonomy, perceived justice...
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A mechanistically approached review upon assorted cell lines stimulated by athermal electromagnetic irradiation
PublicationThe probable influence of electromagnetic irradiation on cancer treatment has been deduced from the interaction of artificial electromagnetic emissions with biological organisms. Nonetheless, the suspected health effects induced by electromagnetic-based technology imply that such a treatment may contaminate the adjacent healthy cells. Thus, gaining mechanistic insights into the problem is required to avoid athermal health hazards....
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Post-match recovery profile of leukocyte cell subsets among professional soccer players
PublicationThis study assessed the impact of cumulative match time on the distribution of CD45+ cell subtests in the capillary blood of professional soccer players. Twenty-two males (aged 18–30 years) took part in the 36-week study. Participants playing up to 540 in cumulative match time and less than 30 min in each single match during the observation period formed the control group. White blood cell (WBC) phenotyping and creatine kinase...
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Sustainable energy system combined biogas-feedSolid Oxide Fuel Cell and Microalgae technology
PublicationIn the new frontier of energy and environmental safety, new efficient and clean safe energy conversion systems are required. In this sense, the present work is framed within the context of Circular Economy and proposes a multidisciplinary study for the development of more efficient, economically viable and non-polluting energy conversion systems, based on the synergetic combination of different technologies: fuel cells, biofuels,...
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Modulated photocurrents in a sandwich-cell structure: II. Influence of biasillumination intensity and carrier diffusion
PublicationPodano przybliżone wyrażenia opisujące modulowane fotoprądy (na podstawiemodelu wielokrotnego pułapkowania) w uwzględnieniem czynników wymienionych wtytule. Zbadano numerycznie ich wpływ na modulowane fotoprądy dla modelowychrozkładów pułapek. Otrzymano wzór - kryterium zaniedbania wpływu dyfuzji nafotoprądy.
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Anode supported single chamber solid oxide fuel cell in CH4-Air Mixture.
PublicationW tej pracy przedstawiono wyniki prac ogniw paliwowych na bazie elektrolitu z tlenku cyrkonu stabilizowanego itrem o grubości 1-2um wytworzonego na podłożu cermetu z tlenku niklu i tlenku cyrkonu stabilizowanego itrem. LSCF był wykorzystany jako katoda. Ogniwo paliwowe było testowane w konfiguracji jednokomorowej w mieszaninie powietrza i metanu. Uzyskano napięcie o wartości 0.8V, zaś moc wynosiła 0.12W/cm2. Zbdadano wpływ przepływu...
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Dynamic impedance measurements of the Direct Methanol Fuel Cell cathode at various operating temperatures
PublicationThis article discusses the application of impedance analysis for diagnosing the cathode of a direct methanol fuel cell at various operating temperatures. The Dynamic Electrochemical Impedance Spectroscopy technique coupled with a linear current scan was applied for this purpose. This technique allowed the observation of changes in the cathode's properties in the fuel cell operating under real working conditions. An equivalent model...
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A Closed Bipolar Electrochemical Cell for the Interrogation of BDD Single Particles: Electrochemical Advanced Oxidation
PublicationA closed bipolar electrochemical cell containing two conductive boron-doped diamond (BDD) particles of size 250 – 350 m, produced by high-pressure high-temperature (HPHT) synthesis, has been used to demonstrate the applicability of single BDD particles for electrochemical oxidative degradation of the dye, methylene blue (MB). The cell is fabricated using stereolithography 3D printing and the BDD particles are located at either...
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Effect of cathode materials on the performance of single chamber solid oxide fuel cell and module
PublicationW pracy przedstawiono wyniki badań nad jednokomorowym ogniwem paliwowym. Badane były ogniwa przygotowane z różnymi rodzajami materiałow katodowych oraz określana była wydajność ogniwa. Zbudowano i zbadano moduł ogniwa paliwowego jednokomorowego.
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The role of the One-Belt One-Road initiative in China's exports and global value chains
PublicationResearch background: China is regarded as the “world factory” highly involved in international trade and plays an increasingly important role in the global value chains (GVC). Additionally, the “One-Belt One-Road” (OBOR) initiative was proposed by the Chinese government to further promote China in the international market. Purpose of the article: The article explores the role of the OBOR in China’s exports and global value...
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Algoritmically improved microwave radar monitors breathing more acurrate than sensorized belt
PublicationThis paper describes a novel way to measure, process, analyze, and compare respiratory signals acquired by two types of devices: a wearable sensorized belt and a microwave radar-based sensor. Both devices provide breathing rate readouts. First, the background research is presented. Then, the underlying principles and working parameters of the microwave radar-based sensor, a contactless device for monitoring breathing, are described....
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Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity
PublicationSeven conjugates composed of well-known fluoroquinolone antibacterial agents, ciprofloxacin (CIP) or levofloxacin (LVX), and a cell-penetrating peptide transportan 10 (TP10-NH2) were synthesised. The drugs were covalently bound to the peptide via an amide bond, methylenecarbonyl moiety, or a disulfide bridge. Conjugation of fluoroquinolones to TP10-NH2 resulted in congeners demonstrating antifungal in vitro activity against human...
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Does the Use of Cell Phones and Headphones at the Signalised Pedestrian Crossings Increase the Risk of Accident?
PublicationReduction of the number of fatalities among pedestrians remains a topical issue in Poland. For many years, this percentage has remained at around 30% of all those who were killed on the road. At the same time, there is an increase in the use of electronic devices by pedestrians and cyclists that may affect their perception when crossing the road. This can lead to traffic accidents. In order to investigate the problem, field studies...
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Free randomness amplification using bipartite chain correlations
PublicationA direct analysis of the task of randomness amplification from Santha-Vazirani sources using the violation of the chained Bell inequality is performed in terms of the convex combination of no-signaling boxes required to simulate quantum violation of the inequality. This analysis is used to find the exact threshold value of the initial randomness parameter from which perfect randomness can be extracted in the asymptotic limit of...
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Sebastian Molin dr hab. inż.
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Cancer Cell International
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CELL BIOCHEMISTRY AND BIOPHYSICS
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Cell Death and Disease
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Krzysztof Czerwionka dr hab. inż.
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Correction: Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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Grzybolubka purchawkowata Asterophora lycoperdoides (Bull.) Ditmar w Dolinie Samborowo w Lasach Oliwskich (Pomorze Gdańskie) = Powdery Piggyback Asterophora lycoperdoides (Bull.)Ditmar in Samborowo Valley at Oliwskie Forests (Gdańsk Pomerania)
PublicationW pracy przedstawiono grzybolubkę oraz omówiono budowę grzybolubki purchawkowatej. Zaprezentowano stanowisko tego gatunku w Dolinie Samborowo w Lasach Oliwskich oraz podano postulaty ochronne.
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Synthesis and Testing of BCZY/LNZ Mixed Proton–electron Conducting Composites for Fuel Cell Applications
PublicationA composite of BaCe0.6Zr0.2Y0.2O3–δ and Li2O:NiO:ZnO was investigated for fuel cell applications. The composite was successfully synthesized and its phase stability was confirmed at temperatures up to 900 °C. The influence of sintering and pressing aids on density was also investigated. Electrical properties were measured. DC electrical conductivity was about 8•10-4 S/m at 845 K. Open circuit voltage measurements in wet hydrogen...
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Optimal spindle speed determination for vibration reduction during ball-end milling of flexible details
PublicationIn the paper a method of optimal spindle speed determination for vibration reduction during ball-end milling of flexible details is proposed. In order to reduce vibration level, an original procedure of the spindle speed optimisation, based on the Liao–Young criterion, is suggested. As the result, an optimal, constant spindle speed value is determined. For this purpose, on-stationary computational model of machining process is...
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Performance of the PEM fuel cell module. Part 2. Effect of excess ratio and stack temperature
PublicationThe paper describes a fuel cell based system performance under different thermal conditions. The system could be fed with bottled hydrogen or with very high purity hydrogen obtained from reforming of methanol. The system is based on two fuel cell units (1.2 kW each, produced by Ballard Power Systems Inc. and called Nexa), DC/DC converter, DC/AC inverter, microprocessor control unit, load unit, bottled hydrogen supply system and...
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Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice
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Haloperidol, but not olanzapine, may affect expression of PER1 and CRY1 genes in human glioblastoma cell line
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Fully enzymatic mediatorless fuel cell with efficient naphthylated carbon nanotube-laccase composite cathodes
PublicationAn efficient, mediator-free enzymatic glucose/O2 biofuel cell with an oxygen intensive anode based on glucose dehydrogenase is presented. In the device,the power of the biofuel cell and electrode potentials of each of the enzymatic electrodes were monitored in parallel under the biofuel cell working conditions. The carbon nanotube composite biocathode demonstrates an almost constant electrode potential vs. saturated calomel electrode...
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Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines
PublicationEpidemiological studies have shown that consumption of cab- bage and sauerkraut is connected with significant reduction of breast cancer incidences. Estrogens are considered a major breast cancer risk factor and their metabolism by P450 enzymes substan- tially contributes to carcinogenic activity. The aim of this study was to investigate the effect of cabbage and sauerkraut juices of differ- ent origin on the expression profile...
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Study of Direct Methanol Fuel Cell Process Dynamics Using Dynamic Electrochemical Impedance Spectroscopy
PublicationA new technique, which was developed to characterize the direct methanol fuel cell under work conditions, has been presented in this paper. The impedance measurements were made using dynamic electrochemical impedance spectroscopy research technique in the galvanostatic mode, using multiple sinusoidal excitation. Obtained results show, that together with an increase of the temperature and working load, the global impedance...
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Steady-state characteristics and dynamic response of the PEM fuel cell to unit step change of load
PublicationPodano opis układu zasilania opartego na dwóch ogniwach paliwowych typu PEM o łącznej mocy 2.4 kW. Zaprezentowano wybrane charakterystyki statyczne i dynamiczne układu.
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PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties
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Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
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Measurement of idlers rotation speed in belt conveyors based on image data analysis for diagnostic purposes
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Rapeseed Meal Waste Biomass as Single-Cell Protein Substrate for Nutritionally-Enhanced Feed Component
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Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studies
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p53 Gene status in relation to ex vivo chemosensitivity of non-small cell lung cancer
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Neuronal Nitric Oxide Synthase-Mediated Genotoxicity of 2-Methoxyestradiol in Hippocampal HT22 Cell Line
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Magnetic properties of Co/Pd multilayered films on porous Al2O3 templates with developed cell substructure
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Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines
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Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: A microarray approach
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Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
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Maintenance therapy with everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis (the EMINENTS study)
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Rotating Magnetic Field-Assisted Reactor Enhances Mechanisms of Phage Adsorption on Bacterial Cell Surface
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Design of polymeric thin films with nanovolcanoes for trapping hydroxyapatite nanoparticles to promote or inhibit cell proliferation
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A novel method for vibration surveillance during high speed ball end milling of flexible details
PublicationPraca dotyczy nadzorowania drgań podczas obróbki zakrzywionych przedmiotów podatnych frezem kulistym, z uwzględnieniem zgodności parametrów modelu modalnego. Przedstawiono analizę dynamiki niestacjonarnego okładu drgającego, z którego wydzielono podukład modalny, strukturalny i łączący. Zastosowano minimalizację poziomu drgań z dopasowaniem prędkości obrotowej wrzeciona do optymalnego kąta przesunięcia fazowego. Eksperymenty doświadczalne...
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A novel method for vibration surveillance during high speed ball end milling of flexible details
PublicationPraca dotyczy nadzorowania drgań układów niestacjonarnych modelowanych metodą elementów skończonych. Obróbka frezem kulistym przedmiotów podatnych jest często stosowana w przypadku nowoczesnych centrów obróbkowych. Drgania względne narzędzie-przedmiot obrabiany mogą doprowadzić do utraty stabilności i powstania drgań samowzbudnych typu chatter. W pracy proponuje się metodę minimalizacji poziomu drgań poprzez dopasowanie prędkości...
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Central nervous system prophylaxis with intrathecal liposomal cytarabine in diffuse large B‑cell lymphomas
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SURFACE TEXTURE ANALYSIS AFTER BALL END MILLING WITH VARIOUS SURFACE INCLINATION OF HARDENED STEEL
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Biochemical properties of thyroid peroxidase (TPO) expressed in human breast and mammary-derived cell lines
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China’s Belt and Road Initiatives (BRI) in South Asia and Its Policy Challenges to India in the Region
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Optimisation of machining parameters during ball end milling of hardened steel with various surface inclinations
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Modulation of cellular response to anticancer treatment by caffeine:inhibition of cell cycle checkpoints, DNA repair and more
PublicationKofeina i inne metyloksantyny wywołują bardzo różne efekty fizjologiczne w organizmie człowieka. W pracy przedstawiamy, które z tych efektów mogą wpływać na skuteczność terapii przeciwnowotworowych. Kofeina może bezpośrednio wpływać na transport oraz aktywację metaboliczną cząsteczek leków do komórki, poprzez tworzenie kompleksów z lekami zawierającymi układy poliaromatyczne. Kofeina hamuje aktywność kinaz ATM/ATR co prowadzi do...