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Search results for: MTA-FOSFORYLAZA
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The Effect of Surface Modification of Ti13Zr13Nb Alloy on Adhesion of Antibiotic and Nanosilver-Loaded Bone Cement Coatings Dedicated for Application as Spacers
PublicationSpacers, in terms of instruments used in revision surgery for the local treatment of postoperative infection, are usually made of metal rod covered by antibiotic-loaded bone cement. One of the main limitations of this temporary implant is the debonding effect of metal–bone cement interface, leading to aseptic loosening. Material selection, as well as surface treatment, should be evaluated in order to minimize the risk of fraction...
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The antitumor compound triazoloacridinone C-1305 inhibits FLT3 kinase activity and potentiates apoptosis in mutant FLT3-ITD leukemia cells.
PublicationAim: FMS-like receptor tyrosine kinase (FLT3) is expressed in some normal hematopoietic cell types and plays an important role in the pathogenesis of acute myeloid leukemia (AML). In this study, we examined the effects of triazoloacridinone C-1305, an antitumor compound, on AML cells with different FLT3 status in vitro. Methods: A panel of human leukemic cell lines with different FLT3 status was used, including FLT3 internal tandem...
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Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine
PublicationConventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. This study aims to investigate the antitumor capacity of Hypericum alpestre (H. alpestre) extract in vitro and in vivo, either alone or in combination with the inhibitors of the L‐arginine/polyamine/nitric oxide...
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Recycled rubber wastes-based polymer composites with flame retardancy and electrical conductivity: Rational design, modeling and optimization
PublicationPolymer recycling techniques experience a maturity period of design and application. Rubbers comprise a high proportion of polymer wastes, highly flammable and impossible to re-melt. Polymer composites based on ground tire rubber (GTR) and ethylene-vinyl acetate copolymer (EVA) containing carbon black (CB) (1–50 phr), with variable EVA/GTR weight composition (10/90, 25/75, 50/50, 75/25 and 90/10), and processing temperature (Low:...
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Usability of Mobile Applications: A Consolidated Model
PublicationMobile devices have become an integral part of the digital ecosystem, connecting people, businesses, and information around the world in ways never before possible. In particular, smartphones, tablets and other handheld devices equipped with mobile applications have changed every aspect of our lives. Today, a user can choose from nearly five million applications available for both Android and iOS operating systems. However, only...
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublicationA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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Green porous benzamide-like nanomembranes for hazardous cations detection, separation, and concentration adjustment
PublicationGreen biomaterials play a crucial role in the diagnosis and treatment of diseases as well as health-related problem-solving. Typically, biocompatibility, biodegradability, and mechanical strength are requirements centered on biomaterial engineering. However, in-hospital therapeutics require an elaborated synthesis of hybrid and complex nanomaterials capable of mimicking cellular behavior. Accumulation of hazardous cations like...
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Products of Photo- and Thermochemical Rearrangement of 19-Membered di-tert-Butyl-Azoxybenzocrown
PublicationThe preparation and characterization of products of the photochemical and thermochemical rearrangements of 19-membered azoxybenzocrowns with two, bulky, tert-butyl substituents in benzene rings in the para positions to oligooxyethylene fragments (meta positions to azoxy group, i.e., t-Bu-19-Azo-O have been presented. In photochemical rearrangement, two colored typical products were expected, i.e., 19-membered o-hydroxy-m,m′-di-tert-butyl-azobenzocrown...
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The evidence for the impact of policy on physical activity outcomes within the school setting: A systematic review
PublicationPurpose Despite the well-established health benefits of physical activity (PA) for young people (aged 4–19 years), most do not meet PA guidelines. Policies that support PA in schools may be promising, but their impact on PA behavior is poorly understood. The aim of this systematic review is to ascertain the level and type of evidence reported in the international scientific literature for policies within the school setting that...
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Group-9 Transition-Metal Suboxides Adopting the Filled-Ti2Ni Structure: A Class of Superconductors Exhibiting Exceptionally High Upper Critical Fields
PublicationTi2Ni and the related η-carbide structure are known to exhibit various intriguing physical properties. The Ti2Ni structure with the cubic space group Fd3̅m is surprisingly complex, consisting of a unit cell with 96 metal atoms. The related η-carbide compounds correspond to a filled version of the Ti2Ni structure. Here, we report on the structure and superconductivity in the η-carbide-type suboxides Ti4M2O with M = Co, Rh, and Ir....
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Gender approach to multi-objective optimization of detection systems by pre-selection of criteria
PublicationA novel idea of performing evolutionary computations for solving highly-dimensional multi-objective optimization (MOO) problems is proposed. The information about individual genders is applied. This information is drawn out of the fitness of individuals and applied during the parental crossover in the evolutionary multi-objective optimization (EMO) processes. The paper introduces the principles of the genetic-gender approach (GGA)...
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Solving highly-dimensional multi-objective optimization problems by means of genetic gender
PublicationPaper presents a computational optimization study using a genetic gender approach for solving multi-objective optimization problems of detection observers. In this methodology the information about an individual gender of all the considered solutions is applied for the purpose of making distinction between different groups of objectives. This information is drawn out of the fitness of individuals and applied during a current parental...
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Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture
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The accuracy of pulse rate estimation from the sequence of face images
PublicationThe goal of this paper is to analyze the accuracy of pulse rate estimation from the sequence of face images. Simulated and real signals were used to evaluate two pulse rate estimators; one for frequency domain and the second one for time domain using the autocorrelation function. The results show that the mean difference between the reference measurements and estimated pulse rate values are about 2bpm. In the analysis of short...
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Phosphorus modified hollow, porous Nickel-Cobalt oxides nanocubes with heterostructure for oxygen evolution reaction in alkaline
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Novel cobalt-free BaFe1−xGdxO3−δ perovskite membranes for oxygen separation
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Gender approach to multi-objective optimization of detection systems by pre-selection of criteria
PublicationA novel idea of performing evolutionary computations for solving highly-dimensional multi-objective optimization (MOO) problems is proposed. The information about individual genders is applied. This information is drawn out of the fitness of individuals and applied during the parental crossover in the evolutionary multi-objective optimization (EMO) processes. The paper introduces the principles of the genetic-gender approach (GGA)...
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Study of Direct Methanol Fuel Cell Process Dynamics Using Dynamic Electrochemical Impedance Spectroscopy
PublicationA new technique, which was developed to characterize the direct methanol fuel cell under work conditions, has been presented in this paper. The impedance measurements were made using dynamic electrochemical impedance spectroscopy research technique in the galvanostatic mode, using multiple sinusoidal excitation. Obtained results show, that together with an increase of the temperature and working load, the global impedance...
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Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension
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Microwave-assisted preparation of Li3V2(PO4)3/C composite with high-rate capacity
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A new time-frequency detection method of stray current field interferenceon metal structures.
PublicationA new detection method has been presented of stray current field interference on underground metal structures. The method employs short time Fourier transformation (STFT). This method of analysis allows determination of signal spectral power density changes (e.g., structure potential) in the function of time. In the paper results have been presented of total time–frequency analysis of a pipeline potential in a stray current field...
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Co w architekturze piszczy? Dźwiękowy wymiar przestrzeni / What’s the buzz in architecture? – The sonic aspect of space
PublicationThe article presents a debate on the dividing line between architecture and the sound sciences. It sketches out the theoretical and practical aspects of space development in the context of its sonic reception. The analysis is based on examples of projects combining architecture and art in public space and their consequences for the reception of this space. The projects relate to the use of art in urban space with special emphasis...
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On the impact of Big Data and Cloud Computing on a scalable multimedia archiving system
PublicationMultimedia Archiver (MA) is a system build upon the promise and fascination of the possibilities emerging from cloud computing and big data. We aim to present and describe how the Multimedia Archiving system works for us to record, put in context and allow a swift access to large amounts of data. We introduce the architecture, identified goals and needs taken into account while designing a system processing data with Big Data...
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The Concept of a Methodology for Selecting the Optimal Parameters of Heat Received from a Nuclear Power Plant Operating in a Partial Cogeneration Mode
PublicationThe paper presents the concept of the objective function which is to allow the selection of optimal parameters of the district heating system using a nuclear power plant operating in partial cogeneration mode. The concept is based on research carried out a number of years ago. The size of annual expenses was proposed as the objective function, which allows to compare the operation of a nuclear power plant in partial cogeneration...
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Elastic scattering of electrons from chloroform
PublicationWe present experimental and theoretical cross sections for elastic electron scattering from CHCl3. This is an important target because of its relevance to environmental chemistry and the plasma etching industry as a source of chlorine radicals. The experimental results were obtained at incident electron energies ranging from 0.5 to 800 eV in the 10deg-130deg scattering angle range. Theoretically, the scattering cross sections in...
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Organisatorische Probleme des Niederschlagwasser – Management in Polen
PublicationIn Polen dominiert in der Kanalisation das Trennsystem. Nur im Zentrum größerer Städte herrscht hauptsächlich das Mischsystem vor. Bezüglich Niederschlagswasser gibt es in Polen keine Festlegungen. Es gibt keine Definition der Verantwortlichkeiten für die Niederschlagswasserentsorgung sowie deren Finanzierung. Trotz Änderungen im Gesetz über die öffentliche Wasserver-und Abwasserentsorgung wurde dieses Problem bislang nicht...
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Transformation of the countryside into an open-air museum as a way to rescure its spatial layout and to improve the quality of live = Przekształcenie wsi w muzeum na wolnym powietrzu jako sposób ratowania jej układu przestrzennego i poprawy jakości życia mieszkańców
PublicationSince the first open-air museums until today, the exposition subject-matter has been specialized (ethnographic, archeological, industrial and technical skansens). But idea of the existence of such objects remains unchanged. Still, the goal is to show the collection of wooden buildings in the environment as close to their origin as possible or in the home environment. These distinguish the skansens and make them different then municipal...
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The multivariate multilevel analisis of different regional factors impact on road saferty in european country regions = Wielopoziomowa analiza wieloczynnikowa wpływu różnych charakterystyk regionalnych na poziom bezpieczeństwo ruchu w regionach krajów europejskich
PublicationIn this research, the effect of the European regional differences on the risk of been killed in road accident in these regions is investigated. Factors which differentiate regions can be described as automotive, economic, infrastructural, demographic, geographic. Analyzed risk, counted as regional fatality rate was modeled by the Poisson model. Because of regional diversity of Poisson distribution parameters, the Poisson distribution...
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ANALYSIS OF THE POSSIBILITIES OF HIGH SPEED SHAFT BEARING SYSTEM DURABILITY INCREASE
PublicationDuring the operation of wind turbines with a gearbox of traditional configuration, a high failure rate of high-speed shaft bearings is observed. Such a high failures frequency is not reflected in standard bearing durability calculation methods, which can be attributed to atypical failure mechanism. To avoid observed problems in the 1.5 MW wind turbine, the modification of the existing bearing system is proposed. Multiple options,...
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SELECTION OF DIAGNOSTIC FUNCTIONS IN A WHEELED TRACTOR
PublicationIn a classical approach to damage diagnosis, the technical condition of an analyzed machine is identified based on the measured symptoms, such as performance, thermal state or vibration parameters. In wheeled tractor the fundamental importance has monitoring and diagnostics during exploitation concerning technical inspection and fault element localizations. The main functions of a diagnostic system are: monitoring tractor components...
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Effect of Cl/Ni molar ratio on the catalytic conversion of polypropylene into Cu–Ni/C composites and their application in catalyzing “Click” reaction
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High Efficiency Dual-Active-Bridge Converter with Triple-Phase-Shift Control for Battery Charger of Electric Vehicles
PublicationAn optimal modulation scheme with triple-phase-shift (TPS) control could increase the efficiency in the entire load range for a dual-active-bridge (DAB) converter under wide output voltage range conditions. Therefore, this study proposes a convergent approach to TPS mode selection, coupled with an optimal modulation scheme, ensuring the circuit’s efficiency over the entire range in the realm of a high-power and high-efficiency...
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Analityka surfaktantów w próbkach środowiskowych
PublicationSurfaktanty stanowią grupę związków charakteryzujących się specyficznymi właściwościami fizykochemicznymi (m.in. amfifilowa budowa, zdolność rozpuszczania się w cieczach o różnej polarności, zdolność do tworzenia micelli) i z tego względu są one wykorzystywane w wielu sferach działalności człowieka. Związki powierzchniowo-czynne ulegają różnorodnym przemianom fizykochemicznym, co umożliwia ich migrację między różnymi elementami...
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Development of Biocompatible Fe3O4@SiO2 Nanoparticles as Subcellular Delivery Platform for Glucosamine-6-phosphate Synthase Inhibitors
PublicationNumerous inhibitors of glucoseamine-6-phophate synthase (GlcN-6-P), the enzyme responsible from catalysis of the first step of metabolic pathway leading to metabolism 5’-diphospho-N-acetyl-D- glucosamine, were reported as effective agents for inhibiting the growth of various fungal pathogens. Among the reported inhibitors,...
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Rationale and design of a large registry on renal denervation: the Global SYMPLICITY registry
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Thermoluminescence glow curves and deconvoluted glow peaks of Ge doped flat fibers at ultra-high doses of electron radiation
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Large-Scale and Highly Efficient Production of Ultrafine PVA Fibers by Electro-Centrifugal Spinning for NH3 Adsorption
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High pressure studies of Eu2+ and Mn2+ doped NaScSi2O6 clinopyroxenes
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Night in a big city. Light festivals as a creative medium used at night and their impact on the authority, significance and prestige of a city
PublicationCities in times of global urbanization, are looking for completely new marketing methods, one such tool is the creative use of artificial light after dark, in the form of light festivals. This paper aims to introduce the historical development of the phenomenon and contemporary as well as contemporary illuminations / projects of illuminations of Fete des Lumieres festival in Lyon, Luminale in Frankfurt or on a smaller scale Lights...
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The thermoluminescence glow curve and the deconvoluted glow peak characteristics of erbium doped silica fiber exposed to 70–130 kVp x-rays
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Review of hydrogen production technologies for automotive sector – thermodynamic analysis of energy and exergy losses
PublicationFew recent years has shown that hydrogen technology has a good chance to replace petroleum technology in automotive sector. However, hydrogen in pure form practically does not occur on Earth. That is why H2 form is used only as an energy carrier and it must be produced using another source of energy form water or hydrocarbon fuels. In this paper short overview of hydrogen production technology has been presented, with energy and...
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Data and knowledge supporting decision-making for the urban Food-Water-Energy nexus
PublicationCities are hubs of innovation and wealth creation, and magnets for an increasing urban population. Cities also face unprecedented challenges in terms of food, water and energy scarcity, and governance and management. Urban environmental issues are no longer problems for experts to address but have become issues of public debate, in which knowledge from multiple sectors is needed to support inclusive governance approaches. Consequently,...
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Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin
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Antecedents and Consequences of Brand Loyalty
PublicationThe objective of this paper is to review, systematize, and summarize empirical research on the antecedents and consequences of brand loyalty. The literature review has identified five categories of antecedents to brand loyalty associated with consumer, brand, social, corporate and relational factors. The type of loyalty formed varies according to the combination of various antecedents, with premium loyalty being considered the...
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Identification of models and signals robust to occasional outliers
PublicationIn this paper estimation algorithms derived in the sense of the least sum of absolute errors are considered for the purpose of identification of models and signals. In particular, off-line and approximate on-line estimation schemes discussed in the work are aimed at both assessing the coefficients of discrete-time stationary models and tracking the evolution of time-variant characteristics of monitored signals. What is interesting,...
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Scenarios in the development strategies of larger cities in Poland
PublicationSummary: Planning prepares decisions and future actions. Therefore, future conditions should be considered in planning, in particular strategic planning, due to its long-term nature. To accomplish this, certain prognostic methods should be applied. A scenario method is seen as one of the most useful prognostic method, especially in cases when social and institutional behaviour plays a crucial role. The aim of the paper is an analysis...
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Zarządzanie tożsamością w organizacjach na różnych poziomach zagregowania
PublicationNiniejszy artykuł stanowi naukową refleksję nad pojęciem tożsamości grupowej, odnoszonej do przedsiębiorstw oraz ich agregatów, określanych przez autorkę mianem „organizacji na wyższych poziomach zagregowania”. Głównym celem artykułu jest przegląd literatury z zakresu tożsamości przedsiębiorstwa, a na tej podstawie próba ustalenia czym jest taka tożsamość i co się na nią składa. Na wstępie autorka przedstawia definicje tożsamości...
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Co-Living or a “Sandpit” for Future Entrepreneurs. First Experience from Poland.
PublicationNowadays, the Western world seems saturated with the myriad of enhancements for entrepreneurship development. Also, in Eastern European countries we observe a growing number of initiatives at different organizational levels, aiming at accompanying potential future entrepreneurs in their efforts. Meanwhile, there is one novelty, never before offered on the Polish market – the first co- -living space, launched in Gdañsk. Therefore,...
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Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial
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Efficient Luminescence from CsPbBr3 Nanoparticles Embedded in Cs4PbBr6
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