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Search results for: MINING TREMOR
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Smart experience engineering to support collaborative design problems based on constraints modelling
PublicationEngineering design is a knowledge intensive process. Experts' experiences from different product life-cycle stages play a key role in problem solving during design decision making by linking up knowledge to find better solutions for a specific design problem. Different approaches have been used to support Collaborative and Concurrent Product Design, such as Constraint Satisfaction Problem (CSP) modelling. Additionally, due to the...
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Forecasting energy consumption and carbon dioxide emission of Vietnam by prognostic models based on explainable machine learning and time series
PublicationThis study assessed the usefulness of algorithms in estimating energy consumption and carbon dioxide emissions in Viet- nam, in which the training dataset was used to train the models linear regression, random forest, XGBoost, and AdaBoost, allowing them to comprehend the patterns and relationships between population, GDP, and carbon dioxide emissions, energy consumption. The results revealed that random forest, XGBoost, and AdaBoost...
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Analiza wielokryterialna wariantów systemu zaopatrzenia w wodę zespołu padów
PublicationJednym z istotnych problemów decyzyjnych na etapie potencjalnej eksploatacji gazu z formacji łupkowych jest wybór sposobu zaopatrzenia w wodę kopalni gazu łupkowego. Z uwagi na duże zapotrzebowanie na wodę do procesu szczelinowania kolejno przekazywanych do eksploatacji odwiertów wydobywczych, należy poszukiwać systemu zaopatrzenia w wodę, który zagwarantuje wymaganą jej ilość, a jednocześnie nie będzie zbyt dużym obciążeniem dla...
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Big Data i 5V – nowe wyzwania w świecie danych (Big Data and 5V – New Challenges in the World of Data)
PublicationRodzaje danych, składające się na zbiory typu Big Data, to m.in. dane generowane przez użytkowników portali internetowych, dane opisujące transakcje dokonywane poprzez Internet, dane naukowe (biologiczne, astronomiczne, pomiary fizyczne itp.), dane generowane przez roboty w wyniku automatycznego przeszukiwania przez nie Internetu (Web mining, Web crawling), dane grafowe obrazujące powiązania pomiędzy stronami WWW itd. Zazwyczaj,...
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FEM Calculations in Analysis of Steel Subsea Water Injection Flowlines Designing Process
PublicationPaper describes the result of theoretical research aimed at assessing the loads and operating conditions of a Coiled Tubing pipeline injecting water, suspended to the mining platform of Lotos Petrobaltic. For this purpose, appropriate calculation models have been developed using the Finite Element Method (FEM), taking into account the nature of the analyzed object and its loads. The analyzes were carried out for two pipes (previously...
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Validation of Services Supporting Healthcare Standards Conformance
PublicationThe paper presents the results of experimental validation of a set of innovative software services supporting processes of achieving, assessing and maintaining conformance with standards and regulations. The study involved several hospitals implementing the Accreditation Standard promoted by the Polish Ministry of Health. First we introduce NOR-STA services that implement the TRUST-IT methodology of argument management. Then we...
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Acoustic journal bearing – Performance under various load and speed conditions speed conditions
PublicationThe paper presents results of experimental testing aiming at finding out what effect system of piezo-electric actuators (PZTs)attached to an aerodynamic journal bearing has on the magnitude of shaft's motion within the bearing operating at specified speed and load. The results clearly demonstrate effectiveness of PZTs in mitigating the shaft's motion thus contributing to the increased stability of the bearing. This stabilizing...
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Azo group(s) in selected macrocyclic compounds
PublicationAzobenzene derivatives due to their photo- and electroactive properties are an important group of compounds finding applications in diverse fields. Due to the possibility of controlling the trans–cis isomerization, azo-bearing structures are ideal building blocks for development of e.g. nanomaterials, smart polymers, molecular containers, photoswitches, and sensors. Important role play also macrocyclic compounds well known for...
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Biochemical, Structural Analysis, and Docking Studies of Spiropyrazoline Derivatives
PublicationIn this study, we evaluated the antiproliferative potential, DNA damage, crystal struc‐ tures, and docking calculation of two spiropyrazoline derivatives. The main focus of the research was to evaluate the antiproliferative potential of synthesized compounds towards eight cancer cell lines. Compound I demonstrated promising antiproliferative properties, especially toward the HL60 cell line, for which IC50 was equal to 9.4 μM/L....
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Novel anticancer strategy aimed at targeting shelterin complexes by the induction of structural changes in telomeric DNA: hitting two birds with one stone.
PublicationThe ends of chromosomes in mammals are composed of telomeric DNA containing TTAGGG repeats, which bind specific proteins called shelterins. This telomeric DNA together with shelterins form a cap that protects the ends of chromosomes from being recognized as sites of DNA damage and from chromosomal fusions. Many very successful antitumor drugs used in the treatment of cancer patients bind to DNA, some of them with a prominent sequence...
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What is important for you makes you think about the pandemic differently: moral foundations, pandemic-related fears and convictions (Lo que cada uno consideramos importante nos hace reflexionar sobre la pandemia de forma distinta: fundamentos morales, temores y convicciones sobre la pandemia)
PublicationBuilding on the Moral Foundations Theory and findings regarding the linkage of values, convictions and beliefs, the aim of the study was to compare people displaying various constellations of moral foundations regarding their tolerance of ambiguity, fear of COVID-19 (FCV), endorsement of COVID-19 conspiracy theories and the extent to which they believed in the effectiveness of five COVID-19 preventive measures. This study was...
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Multiscale model for blood flow after a bileaflet artificial aortic valve implantation
PublicationCardiovascular diseases are the leading cause of mortality in the world, mainly due to atherosclerosis and its consequences. The article presents the numerical model of the blood flow through artificial aortic valve. The overset mesh approach was applied to simulate the valve leaflets motion and to realize the moving mesh, in the aortic arch and the main branches of cardiovascular system. To capture the cardiac system’s response...
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Why do G-quadruplexes dimerize through the 5’-ends? Driving forces for G4 DNA dimerization examined in atomic detail
PublicationG-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid sequences and shown to exist in living cells where they participate in regulation of gene expression and chromosome maintenance. G-quadruplexes with solvent-exposed guanine tetrads show the tendency to associate together through cofacial stacking, which may be important for packaging of G4-forming sequences and allows for the design of higher-order...
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In Search of Naval Beauty. Historical Study of Ship Architecture
PublicationDesigning ships is no mean achievement. In the old days, constructors focused on making their ships visually appealing, while paying scant regard to the living conditions of the crew. Such an approach reflected the state of the art in ship building at the time as well as the social order prevalent in those days. A breakthrough came no earlier than at the turn of the 19th / 20th centuries. The industrial revolution brought along...
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Identification of 1H‐indene‐(1, 3, 5, 6)‐tetrol derivatives as potent pancreatic lipase inhibitors using molecular docking and molecular dynamics approach
PublicationPancreatic lipase is a potential therapeutic target to treat diet-induced obesity in humans, as obesity-related diseases continue to be a global problem. Despite intensive research on finding potential inhibitors, very few compounds have been introduced to clinical studies. In this work, new chemical scaffold 1H-indene-(1,3,5,6)-tetrol was proposed using knowledge-based approach, and 36 inhibitors were derived by modifying its...
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Environmentally Oriented Models and Methods for the Evaluation of Drug x Drug Interaction Effects
PublicationThis detailed review compares known and widely used methods for drug interaction estimation, some of which now have historical significance. Pharmaceutical application has been noted as far back as several thousand years ago. Relatively late in the 20th century, however, researchers became aware that their fate and metabolism, which still remain a great challenge for environmental analysts and risk assessors. For the patient’s...
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Influence of Asphalt Binder on the Compactability of Asphalt Mixtures Using Locking Point
PublicationCompaction is an important process for the asphalt mixture service life. A properly compacted mixture is crucial for long-lasting pavement. The objective of this study was to evaluate the influence of asphalt binders on the compactability of the asphalt mixtures by utilizing the concept of the locking point. To achieve this objective, two compaction methods (impact and gyration), different temperatures and asphalt content, and...
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Prognostic significance of pretreatment VEGF, survivin, and Smac/DIABLO serum levels in patients with serous ovarian carcinoma
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The methylation of a panel of genes differentiates low-grade from high-grade gliomas
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Analiza używania hulajnóg elektrycznych w miastach w kontekście bezpieczeństwa ruchu drogowego na przykładzie Gdańska
PublicationTematem artykułu jest analiza wpływu hulajnóg elektrycznych na bezpieczeństwo ruchu drogowego w miastach, ze szczególnym uwzględnieniem Gdańska. W pierwszej części, która jest teoretycznym wprowadzeniem do tematu, przedstawiono – w oparciu o zagraniczne publikacje – na jaką skalę ludzie na całym świecie korzystają z hulajnóg elektrycznych i jakie zagrożenia z tego wynikają. Z powodu braku polskiej literatury w zakresie tego stosunkowo...
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Some Aspects of Shear Behavior of Soft Soil–Concrete Interfaces and Its Consequences in Pile Shaft Friction Modeling
PublicationThis paper examines the stiffness degradation and interface failure load on soft soil–concrete interface. The friction behavior and its variability is investigated. The direct shear tests under constant normal load were used to establish parameters to hyperbolic interface model which provided a good approximation of the data from instrumented piles. Four instrumented piles were used to obtain reference soil–concrete interface behavior....
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Estimation the rhythmic salience of sound with association rules and neural networks
PublicationW referacie przedstawiono eksperymenty mające na celu automatyczne wyszukiwanie wartości rytmicznych we frazie muzycznej. W tym celu wykorzystano metody data mining i sztuczne sieci neuronowe.
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PROJEKTOWANIE POSADOWIENIA MORSKICH ELEKTROWNI WIATROWYCH NA MORZU BAŁTYCKIM WEDŁUG PRZEPISÓW I ZALECEŃ EUROPEJSKICH
PublicationNiniejszy artykuł prezentuje zagadnienia związane z tematyką projektowania morskich elektrowni wiatrowych. Opisano politykę energetyczną Polski oraz Unii Europejskiej, a także istniejące wytyczne do projektowania turbin morskich. Scharakteryzowano ich konstrukcję, a także sposoby posadowienia. Przedstawiono model obliczeniowy przykładowej elektrowni o mocy 2MW posadowionej na fundamencie palowym - monopalu. W obliczeniach uwzględniono...
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APPLICATION OF THE KOSECKI’S METHOD IN DESIGNING OF OFFSHORE WIND POWER PLANTS FOUNDATION
PublicationThe concept of offshore wind power plants has been well developed in many European countries. There is no such thing as design of offshore wind power plants according to national tradition. The main problem is the lack of standards and guidelines. Ones being applied are Scandinavian or American methods which are not fully adapted to the conditions of the Baltic Sea. The article focuses on the monopile design, as it is currently the...
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Determination of p-y curves for offshore piles based on in-situ soil investigations
PublicationOffshore piles are subjected to complex loads with considerable lateral component. The pile-soil response to lateral loads can be described with the p-y method. For a given depth the load–deflection relationship is built to simulate the surrounding soil stiffness. This state-of-art paper presents a brief discussion of determination methods for the p-y curves using a standard approach based on the soil parameters derived from laboratory...
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Chemometrics for Selection, Prediction, and Classification of Sustainable Solutions for Green Chemistry—A Review
PublicationIn this review, we present the applications of chemometric techniques for green and sustainable chemistry. The techniques, such as cluster analysis, principal component analysis, artificial neural networks, and multivariate ranking techniques, are applied for dealing with missing data, grouping or classification purposes, selection of green material, or processes. The areas of application are mainly finding sustainable solutions...
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Types of Surface Impurities versus the Quality of Brazed Joints
PublicationBrazing is one of the primary joining processes increasingly often applied in industry. Because of their mechanical properties, overlap joints are particularly popular when making brazed structures. The use of brazed joints in structures of critical importance requires that particular attention be paid to joint quality, e.g. by the appropriate cleaning of surfaces to be joined. The article presents results of non-destructive tests...
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Towards a Framework for Context Awareness Based on Textual Process Data
PublicationContext awareness is critical for the successful execution of processes. In the abundance of business process management (BPM) research, frameworks exclusively devoted to extracting context from textual process data are scarce. With the deluge of textual data and its increasing value for organizations, it be-comes essential to employ relevant text analytics techniques to increase the awareness of business process (BP) workers,...
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The impact of sediment, fresh and marine water on the concentration of chemical elements in water of the ice-covered lagoon
PublicationThe common use of chemical elements by man has been contributing to their extraction for centuries. As a consequence, they have been directly or indirectly introduced into the biogeochemical cycle. In the framework of many conventions, mining and processing of elements are currently subject to many restrictions. However, their large load that has already been deposited in the soil and bottom sediments can be remobilised and...
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Smart Approach for Glioma Segmentation in Magnetic Resonance Imaging using Modified Convolutional Network Architecture (U-NET)
PublicationSegmentation of a brain tumor from magnetic resonance multimodal images is a challenging task in the field of medical imaging. The vast diversity in potential target regions, appearance and multifarious intensity threshold levels of various tumor types are few of the major factors that affect segmentation results. An accurate diagnosis and its treatment demand strict delineation of the tumor affected tissues. Herein, we focus on...
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Modeling and MANOVA studies on toxicity and endocrine potential of packaging materials exposed to different extraction schemes
PublicationThe stability of the linings of packaging that is in contact with the goods stored has been of major concern during decades of the development of packaging materials. In this work, an attempt was undertaken to assess the applicability of using two bioassays (Microtox® and XenoScreen YES/YAS) in estimating the stability of packaging (cans, caps, multilayer material) and the impact of their degradation on the toxicity of some simulated media....
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HDAC Inhibitors: Innovative Strategies for Their Design and Applications
PublicationHistone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...
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Lasing modes of infinite periodic chain of quantum wires
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Effective mode volume of a natural mode of an open dielectric resonator with an active region
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Plasmon and structure resonances in the scattering of light by a periodic chain of silver nanocylinders
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Periodicity-induced effects in the scattering and absorption of light by infinite and finite gratings of circular silver nanowires
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Selected anionic and cationic surface active agents: case study on the Kłodnica sediments
PublicationSurface active agents (surfactants) are a group of chemical compounds, which are used as ingredients of detergents, cleaning products, cosmetics and functional products. After use, wastes containing surfactants or their degradation products are discharged to wastewater treatment plants or directly into surface waters. Due to their specific properties of SAAs, compounds are able to migrate between different environmental compartments...
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Digital Government as Implementation Means for Sustainable Development Goals
PublicationOne of the challenges for implementing Sustainable Development Goals (SDGs) is the measurement of indicators that represent progress towards such goals. Measuring such progress enables data-driven decision-making and management of SDG-relevant projects and strategies. The premise of this research is that measuring such indicators depends on measuring so-called means of implementation, i.e. activities that directly contribute to...
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Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies
PublicationA series of novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(6-substituted-4-chloro-1,3,5-triazin-2-ylamino)guanidine derivatives 9–20 have been synthesized by substitution of chlorine atom at the 1,3,5-triazine ring in compounds 5–8 with 3- or 4-aminobenzenesulfonamide and 4-(aminomethyl)benzenesulfonamide hydrochloride. All the synthesized compounds were evaluated for their inhibitory activity toward hCA I, II,...
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Controlled grafting of vinylic monomers on polyolefins: a robust mathematical modeling approach
PublicationExperimental and mathematical modeling analyses were used for controlling melt free-radical grafting of vinylic monomers on polyolefins and, thereby, reducing the disturbance of undesired cross-linking of polyolefins. Response surface, desirability function, and artificial intelligence methodologies were blended to modeling/optimization of grafting reaction in terms of vinylic monomer content, peroxide initiator concentration,...
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Self-healing mechanism of metallopolymers investigated by QM/MM simulations and Raman spectroscopy
PublicationThe thermally induced self-healing mechanisms in metallopolymers based on bisterpyridine complexes of iron(II) sulfate and cadmium(II) bromide, respectively, were studied by means of combined quantum mechanical/molecular mechanical (QM/MM) simulations and Raman spectroscopy. Two possible healing schemes, one based on a decomplexation of the cross-linking complexes and a second one relying on the dissociation of ionic clusters,...
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Discovering Rule-Based Learning Systems for the Purpose of Music Analysis
PublicationMusic analysis and processing aims at understanding information retrieved from music (Music Information Retrieval). For the purpose of music data mining, machine learning (ML) methods or statistical approach are employed. Their primary task is recognition of musical instrument sounds, music genre or emotion contained in music, identification of audio, assessment of audio content, etc. In terms of computational approach, music databases...
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Experimental research on evolutionary path planning algorithm with fitness function scaling for collision scenarios
PublicationThis article presents typical ship collision scenarios, simulated using the evolutionary path planning system and analyses the impact of the fitness function scaling on the quality of the solution. The function scaling decreases the selective pressure, which facilitates leaving the local optimum in the calculation process and further exploration of the solution space. The performed investigations have proved that the use of scaling...
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The impact of natural fibers’ characteristics on mechanical properties of the cement composites
PublicationThe paper reviews the properties of cement composites reinforced with short fibres. The effect of natural fibres was investigated: cotton, sisal, jute, ramie, bamboo, and synthetic fibres: polymer and polypropylene. It was noticed that the fibres change the consistency of the mixture up to 15%. In the composite flexural strength tests, a change in strength by +/− 8% was observed, depending on the type of fibres used. The research...
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Non-destructive inspection of ground anchors using guided wave propagation
PublicationThis paper deals with numerical and experimental investigations of specific problems of guided wave propagation in ground anchors. The research focuses on recognizing the phenomenon of the energy transfer between anchor components. Particular attention is paid to characteristic features of guided waves propagating in free and embedded parts of the tendon, at the interface between the tendon and the surrounding anchor body as well...
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Dynamic deformations tests of Ni3Al based intermetallic alloy by using the split Hopkinson pressure bar technique
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Attempt to a Video-Transmission Capability in MV Mine Cable Network Using BPL-PLC Technology
PublicationThis article presents and discusses the attempt to transmit video content using the BPL-PLC (Broadband over Power Line - Power Line Communication) technology. It includes simulation results of a specially developed digital transmitter and receiver, dedicated to a given predefined 6 kV mining power cable. The effect of two different transmission modes (2-7 MHz and 3-7.5 MHz) and two types of coupling (capacitive-inductive and induction-inductive),...
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Entrained Flow Plasma Gasification of Sewage Sludge–Proof-of-Concept and Fate of Inorganics
PublicationSewage sludge is a residue of wastewater processing that is biologically active and consists of water, organic matter, including dead and living pathogens, polycyclic aromatic hydrocarbons, and heavy metals, as well as organic and inorganic pollutants. Landfilling is on the decline, giving way to more environmentally friendly utilisation routes. This paper presents the results of a two-stage gasification–vitrification system, using...
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Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres
PublicationTelomerase reactivation is one of the hallmarks of cancer, which plays an important role in cellular immortalization and the development and progression of the tumor. Chemical telomerase inhibitors have been shown to trigger replicative senescence and apoptotic cell death both in vitro and in vivo. Due to its upregulation in various cancers, telomerase is considered a potential target in cancer therapy. In this study, we identified...
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LNG TANK IN ŚWINOUJŚCIE: NONLINEAR ANALYSIS OF THE TANK DOME ELEMENTS BEHAVIOUR
PublicationIn this paper, the dome of a tank in the Świnoujście LNG terminal is analysed. Some of the rafter ribs at the connection with hangers were not mounted during construction of the tank dome. Therefore, it has become necessary to estimate its response, which has been done with the aid of some computational models of the dome, that have been created in the finite element method environment. Different local models are studied, aiming...