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Search results for: QDA
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Comparative molecular dynamics study of dimeric and monomeric forms of HIV-1 protease in ligand bound and unbound state
PublicationHuman immunodeficiency virus type 1 protease (HIV-1 PR) is a viral-encoded enzyme that forms a homodimer. HIV-1 PR is essential for replication and assembly of the virus and inactivation of HIV-1 PR enzyme causes production of immature, noninfectious viral particles and thus HIV-1 PR is an attractive target in anti-AIDS drug design. In our current work, we performed molecular dynamics (MD) calculations (500 ns) for two different...
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Investigating an Optimal Computational Strategy to Retrofit Buildings with Implementing Viscous Dampers
PublicationCivil engineering structures may seriously suffer from different damage states re-sult of earthquakes. Nowadays, retrofitting the existing buildings is a serious need among designers. Two important factors of required performance level and cost of retrofitting play a crucial role in the retrofitting approach. In this study, a new optimal computational strategy to retrofit structures by implementing linear Viscous Dampers (VDs)...
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Machine learning-based seismic response and performance assessment of reinforced concrete buildings
PublicationComplexity and unpredictability nature of earthquakes makes them unique external loads that there is no unique formula used for the prediction of seismic responses. Hence, this research aims to implement the most well-known Machine Learning (ML) methods in Python software to propose a prediction model for seismic response and performance assessment of Reinforced Concrete Moment-Resisting Frames (RC MRFs). To prepare 92,400 data...
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Radiosensitization of DNA in presence of Pt(II)-based compounds
PublicationX-ray irradiation of plasmid DNA in presence of platinum (II)-based compounds was carried out in order to assess the radiosensitization capabilities of these drugs. In present investigations pBR322 plasmid DNA was used to monitor the effectiveness of chosen compounds in inducing strand breaks. Samples were incubated in the presence of potential radiosensitisers: platinum (II) bromide and cis-diamminedibromoplatinum (II). The results...
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STUDY IN MECHANICAL FAULT ELEMENT THERMOGRAPHY THROUGH THE MACHINE: The case of deep groove ball bearings of a career without screen.
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Two-phase water-air flow measurement using gamma-ray absorption technique – plug flow
Open Research DataThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: plug flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded using a dedicated EC...
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Two-phase water-air flow measurement using gamma-ray absorption technique – slug flow
Open Research DataThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: slug flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded using a dedicated EC...
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Two-phase water-air flow measurement using gamma-ray absorption technique –bubble flow
Open Research DataThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: bubble flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded using a dedicated...
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Two-phase water-air flow measurement using gamma-ray absorption technique – transitional plug – bubble flow
Open Research DataThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: transitional plug – bubble flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded...
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WebCT - platforma i tłumaczenie.
PublicationW artykule przedstawiono doświadczenia Centrum Edukacji Niestacjonarnej i Międzywydziałowego Koła Naukowego Studentów Politechniki Gdańskiej DEC@TUG w tłumaczeniu i implementacji platform LMS (ang. Learning Management System). Krótko scharakteryzowano funkcjonalność platform BSCW I Moodle, których interfejsy zostały przetłumaczone przez członków Koła DEC@TUG w latach 2000-2003. Opisano główne funkcje platformy WebCT, takie jak...
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Electron mobility variance in semiconductors: the variance approach
PublicationPraca przedstawia nowe podejście da analizy zjawisk losowych w półprzewodnikach. Uwzględnia kilka mechanizmów zjawisk fluktuacji ruchliwości w półprzewodnikach, prowadzących do powstawamai składowej szumów typu 1/f, dominujących w zakresie małych czetotliwości. Przedstawia analizę sposobu wyznaczenia stałej Hooge'a określającej intensywność szumów typu 1/f.The statistical non-triviality of current carrier mobility fluctuations...
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Spektrometria mas jako narzędzie umożliwiające poznanie metabolomu-główne strategie i wyzwania
PublicationBadania z zakresu metabolomiki ukierunkowane są na wykrywanie i oznaczanie endogennych związków małocząsteczkowych o masie <1000 Da (np. aminokwasy, cukry, lipidy) w próbkach biologicznych takich jak płyny biologiczne (głównie krew i mocz) oraz kondensaty wydychanego powietrza. Ze względu na szerokie spektrum występowania i niskie poziomy stężeń metabolitów w próbkach, analizy metabolomiczne wymagają stosowania technik o wysokiej...
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Od podstawy programowej do standardów kształcenia
PublicationWprowadzenie "nowej matury" w prowadzenie nowej matury w 2005 roku zrewolucjonizowało proces rekrutacji na wyższe uczelnie. Szkoły wyższe nie chciały początkowo rezygnować z egzaminów wstępnych, próbując zmienić ich formułę, jednak w 2006 roku Ministerstwo Edukacji ograniczyło możliwości przeprowadzania takich „testów kompetencji” tylko do nielicznych przypadków. Co roku egzamin maturalny zmienia niektóre...
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E-learning course "International comparative studies on SMEs"
PublicationProjekt Leonardo da Vinci "International comparative studies and course development on SMEs" został zainspirowany poprzednim projektem LdV "A European Diploma in SME Management". Bazując na poprzednich doświadczeniach projektowych zaproponowano opracowanie struktur dla opisania narodowych systemów małych i średnich przedsiębiorstw (ang. SME Small Media Enterprises) przy wykorzystaniu dostępnych krajowych danych. Udowodniono, że...
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Performance of a new commercial high-definition 3D patient specific quality assurance system for CyberKnife robotic radiotherapy and radiosurgery
PublicationConventional two dimensional and low-definition measurement techniques for dosimetric verification of radiotherapy treatment deliveries are no longer adequate in the era of hypofractionation and extremely high dose gradients. New quality assurance (QA) tools with 3D capability and high definition are urgently needed. The purpose of this study was to evaluate the performance of one of the first such commercial systems as applied...
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Prezentacja performance "Wrażliwy obserwator", EuropapunktBremen, Brema, Niemcy
PublicationZ każdej szafy da się skoczyć! Jestem w Bremie, za kilka godzin mój pobyt tutaj będzie trwał już równy dzień, pierwszy z wielu. Drapię stopę nad kostką, komar, inny zwierz, nie wiem. Pod paznokciami zostaje skóra, czerwień pionowo obejmuje okolice ugryzienia, przecieram oko i piję łyk kawy. Zjadłem moje pierwsze śniadanie tutaj, piję moją pierwszą kawę, okej drugą, ale pierwszą samemu dla siebie. Kawa z ekspresu, pierwszy raz...
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Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with beta-glucosidase, beta-fucosidase and beta-galactosidase activities.
PublicationBackground: Cold-active enzymes, sourced from cold-adapted organisms, are characterized by high catalytic efficiencies at low temperatures compared with their mesophilic counterparts, which have poor activity. This property makes them advantageous for biotechnology applications as it: (i) saves energy costs, (ii) shortens the times for processes operated at low temperatures, (iii) protects thermosensitive substrates or products...
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Koncepcja kontraktowa w ramach teorii sprawiedliwości wedle Johna Rawlsa
PublicationW eseju usiłowałem rozświetlić zręby J. Rawlsa koncepcji (teorii) kontraktowej. Podjąłem analizę związku koncepcji kontraktu z tzw. sytuacją pierwotną określaną jako taki stan rzeczy, gdzie osoby-strony są na równi reprezentowane jako moralne osoby, a rezultat nie jest bynajmniej determinowany ani ich arbitralnymi przymiotami, ani relatywnym bilansem sił społecznych. Następnie uwypukliłem związek pojęcia "sytuacji pierwotnej"...
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Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
PublicationEndometrial cancer (EC) is the second most common cancer in women. A large number of human cancers exhibit dysregulation of microRNA expression including EC. MiR-15b/16–2 is one of the best-known miRNA clusters that is expressed in many types of cancer tissues. Herein, we analyzed the expression of individual miR-15b/16–2 cluster members, its paralogues, and their target network analysis, as well as their prognostic significance...
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THE GENE CLONING, OVEREXPRESSION, PURIFICATION AND BIOCHEMICAL CHARACTERISATION OF A NEW COLD-ADAPTED β–GALACTOSIDASE FROM ARTHROBACTER SP. VII-4
PublicationINTRODUCTION. β-Galactosidase [EC 3.2.1.23] is an enzyme that catalyzes the hydrolysis of O-glycosidic linkages in galactosides. It is commercially used in dairy industry for the production of milk with reduced lactose content. Potentially, the best method for lactose removal under cooling conditions should be carried out with a cold-adapted enzyme. AIM. The aim of this study was to determine the taxonomic affiliation of the isolate...
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Spatial aspects of urban air quality management: Estimating the impact of micro-scale urban form on pollution dispersion
PublicationUrban planning and design solutions affect urban ventilation conditions, thus mitigating the effects of atmospheric pollution. However, these findings are not being implemented in the planning practice to a sufficient extent, partly due to the lack of specific guidelines. Moreover, many urban air quality monitoring (AQM) sites have low represnentativeness and thus do not provide comprehensive data for effective urban air pollution control...
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Chemistry of human breast milk – a comprehensive review of the composition and role of milk metabolites in child development
PublicationEarly nutrition has an enormous influence on a child's physiological function, immune system maturation and cognitive development. Human breast milk (HBM) is recognized as the gold standard for human infant nutrition. Accordingly to WHO report breastfeeding is consider as an unequalled way of providing ideal food to the infant, which is required for his healthy growth and development. HBM contains various macronutrients (carbohydrates,...
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Quality Assurance and Quality Control in the Analytical Chemical Laboratory: A Practical Approach.
PublicationNowe opracowanie książkowe z zakresu QA/QC to praktyczny podręcznik zarówno dla studentów jak i pracowników laboratoriów. Opisano systemu jakości wyników pomiarów analitycznych i poszczególnych jego składników: spójności pomiarowej, niepewności pomiaru, walidacji procedury analitycznej, materiałów odniesienia i badań międzylaboratoryjnych. Opisano i przedstawiono narzędzia statystyczne służące do obliczania parametrów walidacyjnych,...
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Tecnología y Democracia ¿Un amor de pandemia o una relación estable?
PublicationPrologar una obra como esta es un privilegio y una responsabilidad. Es un privilegio en tanto que da paso a un seguido de contribuciones de gran calado y relevancia académica que contribuyen a la mejora del conocimiento existente acerca de la relación entre la tecnología y el funcionamiento de la democracia. Es una responsabilidad en el sentido que debe poner sobre la mesa algunas de las cuestiones abiertas de la disciplina y como...
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Analytics of Surfactants in the Environment: Problems and Challenges
PublicationSurfactants (surface active agents = SAAs) are a group of compoundswith specific physicochemical properties (amphiphilicity,solubility in polar and nonpolar liquids, ability to form micelles,adsorption at phase boundaries).1,2 Because of their properties,surface-active compounds are widely applied in industry and thehousehold (e.g., in detergents, personal-care products, paints,pesticides, petroleum products). As their applications...
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Surface engineering of graphene oxide membranes for selective separation of perfluorooctanoic acids
PublicationPerfluoroalkyl compounds (PFCs) are environmental toxicants and their widespread detection and accumulation in the environment can be detrimental to the ecosystem. In this study, surface charge of GO membranes was engineered to enhance selectivity of graphene oxide (GO) membranes and for the removal of perfluorooctanoic acid (PFOA ∼400 Da) in real concentration ranges in wastewater streams. The structure and physicochemical properties...
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Apprendere camminando.Il metodo della Jane’s Walk per riscoprire San Lorenzo
PublicationTratta dal libro rivoluzionario che Jane Jacobs, attivista americana, ha scritto negli anni Sessanta e che ben presto è diventato un importante riferimento per la partecipazione dei cittadini nella progettazione urbana, questa citazione ben esprime l’approccio attraverso il quale ci siamo avvicinate alla riscoperta di San Lorenzo. Quartiere della città storica molto conosciuto, San Lorenzo si è rivelato in grado di disvelare paesaggi...
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Zdolni z Pomorza 2019/20 - Kropki i kreski, czyli grafy i ich zastosowania
e-Learning CoursesCel kursu: Celem kursu jest wprowadzanie uczniów w świat grafów i zapoznanie ich z praktycznymi zastosowaniami teorii grafów. Opis kursu: Dawno temu Leonard Euler, jadąc do Petersburga, zatrzymał się po drodze w Królewcu. Tam zainteresował go problem, nad którym, jak wieść niesie, głowili się mieszkańcy tego miasta: czy da się przespacerować po Królewcu tak, aby każdy z jego siedmiu mostów przejść dokładnie raz? Euler podszedł...
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Elastic scattering of electrons from chloroform
PublicationWe present experimental and theoretical cross sections for elastic electron scattering from CHCl3. This is an important target because of its relevance to environmental chemistry and the plasma etching industry as a source of chlorine radicals. The experimental results were obtained at incident electron energies ranging from 0.5 to 800 eV in the 10deg-130deg scattering angle range. Theoretically, the scattering cross sections in...
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Comparison of an Electronic Nose Based on Ultrafast Gas Chromatography, Comprehensive Two-Dimensional Gas Chromatography, and Sensory Evaluation for an Analysis of Type of Whisky
PublicationWhisky is one of the most popular alcoholic beverages. There are many types of whisky, for example, Scotch, Irish, and American whisky (called bourbon). The whisky market is highly diversified, and, because of this, it is important to have a method which would enable rapid quality evaluation and authentication of the type of whisky. The aim of this work was to compare 3 methods: an electronic nose based on the technology of ultrafast...
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublicationPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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Glucosinolates from lepidium peruvianum as potential antiamnestic drugs
PublicationLepidium peruvianum (maca) (Brassicaceae) is a naturally occurring plant mainly in the high Andes of Peru. In recent years, it has been intensively researched in terms of its influence on various diseases and towards health improvement. Alzheimer’s disease is an incurable disease that most often affects adults over the age of 60. As since 2003 the US Food and Drug Administration (FDA) did not approve any new drug for Alzheimer’s...
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Development of fragility curves in adjacent steel moment-resisting frames considering pounding effects through improved wavelet-based refined damage-sensitive feature
PublicationFragility curves present useful information related to earthquake-induced probability assessment of steel moment-resisting frames (MRFs) and determine the probability of the damage exceedance at different floor levels of MRFs. The review of the literature shows that most of the previous studies dealing with the fragility curves were based on conventional measures, such as spectral acceleration at the first mode period, peak...
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Homogeneity study of candidate reference material (contaminated soil) based on determination of selected metals, PCBs and PAHs
PublicationReference materials (RMs) are an indispensable part of QA/QC system and have played a critical role in the continual expansion of analytical capabilities of the analytical laboratories. The homogeneity study of the candidate for reference material is essential for the quality of reference material (certified reference material) used in quality assurance activities. The homogeneity study of candidate for reference materials of contaminated...
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Studies on selectivity of hydrocarbon group type separation of petroleum vacuum distillates and base oils by HPLC.
PublicationW pracy przedstawiono wyniki badań nad doborem selektywnego chromatograficznego układu HPLC, umożliwiającego rozdzielenie grupowe produktów naftowych otrzymanych z destylacji próżniowej ropy naftowej, w tym, mineralnych olejów bazowych. Stwierdzono, że konieczny układ chromatograficzny wymaga wykorzystania dwóch kolumn wypełnionych żelem krzemionkowym ze związanymi grupami nitrofenopropylowymi, połączonych szeregowo z dwiema...
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A simplified approach to determine the expiration date of certified reference material based on the results of monitoring long-term stability
PublicationAll components of the quality assurance (QA) system for measurement results depend heavily on certified reference materials (CRMs). There is a need for a comprehensive discussion of the stability study using the CRM statistical method. Monitoring involves periodic sampling and analysis of the CRM at predetermined intervals to continuously monitor stability without compromising its integrity. The obtained stability data is then...
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Dokładność modeli numerycznych przepływu wód podziemnych jako kryterium ich klasyfikacji
PublicationW artykule podjęto próbę ustalenia klas dokładności numerycznych modeli przepływu wód podziemnych. Wstępnej analizie poddano 14 modeli wykonanych przez autorkę artykułu. Są to modele przepływu wód podziemnych występujących w porowatych utworach kenozoiku lub kredy, a zatem głównie wykonane na obszarze Polski północnej. Analizowano wartości błędów kalibracji, błąd bilansu przepływu, powierzchnię obszaru modelowania, skalę odwzorowania...
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Green TPUs from Prepolymer Mixtures Designed by Controlling the Chemical Structure of Flexible Segments
PublicationThis study concerns green thermoplastic polyurethanes (TPU) obtained by controlling the chemical structure of flexible segments. Two types of bio-based polyether polyols—poly(trimethylene glycol)s—with average molecular weights ca. 1000 and 2700 Da were used (PO3G1000 and PO3G2700, respectively). TPUs were prepared via a two-step method. Hard segments consisted of 4,4?- diphenylmethane diisocyanates and the bio-based 1,4-butanodiol...
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Analysis of Circulating Tumor Cells in Patients with Non-Metastatic High-Risk Prostate Cancer before and after Radiotherapy Using Three Different Enumeration Assays
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027639881]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027634721]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027637621]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027632391]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027636371]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027631391]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027637131]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027633971]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027636481]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027634171]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, biphasic - Male, 12 - Tissue image [6030730027634341]
Open Research DataThis is the histopathological image of CONNECTIVE, SUBCUTANEOUS AND OTHER SOFT TISSUES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.