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Alternative Approach to Convolution Term of Viscoelasticity in Equations of Unsteady Pipe Flow
PublikacjaIn the paper the selected aspects concerning description of viscoelastic behavior of pipe walls during unsteady flow are analyzed. The alternative convolution expression of the viscoelastic term is presented and compared with the corresponding term referring to unsteady friction. Both approaches indicate similarities in the forms of impulse response functions and the parameter properties. The flow memory was introduced into convolution...
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Four-electron correlated integrals arising in the singly-linked Hylleraas method for atomic systems
PublikacjaThe subject of this thesis is the development and implementation of a method for the analytical calculation of the electronic integrals of the explicitly correlated functions of the atomic systems, particularly in the Hylleraas method with one odd correlation factor. In the course of the work, new theoretical methods were developed to obtain all considered the integrals as the closed-form analytic expression with elementary functions...
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Born Twice: The Role of Social Media in Identity Redefinition after Sudden Disability
PublikacjaFrom being attacked by a shark to being stricken by illness, people who acquire disabilities later in life have unique lived experiences. There is, however, a commonality that binds them: the loss of a former identity and a rebirth into another life. They may also struggle with self-acceptance as they shun societal stigmas and perceived deviance from cultural norms. Through a netnographic study, we examine how identities are redefined...
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Comparing Phylogenetic Trees by Matching Nodes Using the Transfer Distance Between Partitions
PublikacjaAbility to quantify dissimilarity of different phylogenetic trees describing the relationship between the same group of taxa is required in various types of phylogenetic studies. For example, such metrics are used to assess the quality of phylogeny construction methods, to define optimization criteria in supertree building algorithms, or to find horizontal gene transfer (HGT) events. Among the set of metrics described so far in...
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Fusion of DNA-binding domain of Pyrococcus furiosus ligase with TaqStoffel DNA polymerase as a useful tool in PCR with difficult targets
PublikacjaThe DNA coding sequence of TaqStoffel polymer- ase was fused with the DNA-binding domain of Pyrococcus furiosus ligase. The resulting novel recombinant gene was cloned and expressed in E. coli. The recombinant enzyme was purified and its enzymatic features were studied. The fusion protein (PfuDBDlig-TaqS) was found to have enhanced processivity as a result of the conversion of the Taq DNA polymerase from a relatively low processive...
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Architektoniczne przestrzenie wspólne dizajnu i sztuki
PublikacjaW aspekcie współczesnego wszechobecnego konsumpcjonizmu i ograniczonych możliwości dotarcia do odbiorcy, role obiektów należących do sztuk czystych przejmują obiekty będące wytworami projektantów w zakresie sztuk użytkowych, w tym architektów. Jednocześnie sztuka poszukuje nowych form i środków wyrazu, żeby wzbudzić zainteresowanie. Rozpatrywanym obiektem jest Dom. Oczywistą jego odsłoną jest spełnienie oczekiwanej funkcji wynikającej...
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Regulation of LPS assembly via controlled proteolysis and sensing of LPS stress in Escherichia coli
PublikacjaLipopolysaccharide (LPS) is a complex glycolipid, essential for the bacterial viability and along with phospholipids, it constitutes the major amphiphilic component of outer membrane (OM) in most of the Gram-negative bacteria, including Escherichia coli. LPS molecules confer an effective permeability barrier to the OM and play a crucial role in bacteria-environment and -host interactions. The synthesis and accumulation of this...
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Regulated assembly of lipopolysaccharide and sensing of its alterations in Escherichia coli
PublikacjaThis thesis describes mechanism of the regulation of the transcription of the rpoE gene encoding an essential RNA polymerase subunit in Escherichia coli. The RpoE regulates extracytoplasmic stress response regulon and is required to initiate transcription of genes, whose products are involvedin the folding of periplasmic proteins and synthesis and transport of outer membrane components. The transcriptional regulation of the rpoE...
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A model of liquid film breakdown formed due to impingement of a two-phase jet on a horizontal surface
PublikacjaThe present work aims to provide an explanation to the phenomenon of breakdown of the thin liquid film created by impinging two-phase, liquid-gas jet. Existing in the literature models describe merely thebreakdown of single phase liquid films. The model presented here is based on examination of mass and energy equations under the applied criterion of the minimum of total energy. That allows to determinethe minimum thickness of...
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Combined spline wavelet decomposition for 3d seafloor imaging from multibeam sonar echoes
PublikacjaThe paper proposes combined spline-wavelet approach to the raw echoes seaflor imaging from Multibeam Sonar System (MBSS) records. Wavelet representation is closely related to image representation, due to its unique approximations properties. Splines have the best approximation properties among all known wavelets of a given order, so they are best suited for approximating of smooth seafloor surface. Additionaly, wavelet bases have...
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Accuracy of the Discrete Green's Function Formulation of the FDTD Method
PublikacjaThis paper reports an evaluation of the accuracy of the discrete Greens function (DGF) formulation of the finite-difference time-domain (FDTD) method. Recently, the closed-form expression for the DGF and its efficient numerical implementation were presented, which facilitates applications of the DGF in FDTD simulations of radiation and scattering problems. So far, the accuracy of the DGF formulation of the FDTD method has been...
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An unorthodox view on the problem of tracking facial expressions
PublikacjaRecent developments in imaging cameras has opened a new way of analyzing facial expression. We would like to take advantage from this new technology and present a method of imaging and processing images of human face as a response to the particular stimuli. The response in this case is represented by the facial expressions and the stimuli are still images representing six basic emotions according to Eckmann. Working hypothesis...
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Dynamic Data Management Among Multiple Databases for Optimization of Parallel Computations in Heterogeneous HPC Systems
PublikacjaRapid development of diverse computer architectures and hardware accelerators caused that designing parallel systems faces new problems resulting from their heterogeneity. Our implementation of a parallel system called KernelHive allows to efficiently run applications in a heterogeneous environment consisting of multiple collections of nodes with different types of computing devices. The execution engine of the system is open for...
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An unorthodox view on the problem of tracking facial expressions
PublikacjaRecent developments in imaging cameras has opened a new way of analyzing facial expression. We would like to take advantage from this new technology and present a method of imaging and processing images of human face as a response to the particular stimuli. The response in this case is represented by the facial expressions and the stimuli are still images representing six basic emotions according to Eckmann. Working hypothesis...
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Uncertainty of the liquid mass flow measurement using the orifice plate
PublikacjaThe article presents an estimation of measurement uncertainty of a liquid mass flow using the orifice plate. This subject is essential because of the widespread use of this type of flow meters. Not only the quantitative estimation but also the qualitative results of those measurements are important. To achieve these results the authors of the paper propose to use the theory of uncertainty. The article shows the analysis of the...
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Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria
PublikacjaIn eukaryotic cells, different organelles interact at membrane contact sites stabilized by tethers. Mitochondrial mitofusin 2 (MFN2) acts as a membrane tether that interacts with an unknown partner on the endoplasmic reticulum (ER). In this work, we identified the MFN2 splice variant ERMIT2 as the ER tethering partner of MFN2. Splicing of MFN2 produced ERMIT2 and ERMIN2, two ER-specific variants. ERMIN2 regulated ER morphology,...
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Impact of the glazed roof on acoustics of historic interiors
PublikacjaThe paper discusses the adverse acoustic phenomena occurring in the semi-open interiors (courtyards, yards) covered with a glass roof. Particularly negative is the rever-beration noise, which leads to the degradation of the utility functions of the resulting spaces. It involves the drastically reducing the intelligibility of speech, loss of natural sounding of music, problems with the sound system, as well as disturbances in the...
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Qualia: About Personal Emotions Representing Temporal Form of Impressions - Implementation Hypothesis and Application Example
PublikacjaThe aim of this article is to present the new extension of the xEmotion system as a computerized emotional system, part of an Intelligent System of Decision making (ISD) that combines the theories of affective psychology and philosophy of mind. At the same time, the authors try to find a practical impulse or evidence for a general reflection on the treatment of emotions as transitional states, which at some point may lead to the...
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Virulence of Clinical Candida Isolates
PublikacjaThe factors enablingCandidaspp. infections are secretion of hydrolytic enzymes, adher-ence to surfaces, biofilm formation or morphological transition, and fitness attributes. The aim of thisstudy was to investigate the correlation between known extracellular virulence factors and survivalofGalleria mellonellalarvae infected with clinicalCandida. The 25 isolates were tested and the activityof proteinases among 24/24, phospholipases...
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Polylysine for Skin Regeneration: A Review of Recent Advances and Perspectives
PublikacjaThere have been several attempts to find promising biomaterials for skin regeneration, among which polylysine (a homopolypeptide) has shown benefits in the regeneration and treatment of skin disorders. This class of biomaterials has shown exceptional abilities due to their macromolecular structure. Polylysine-based biomaterials can not only be used as tissue engineering scaffolds for skin regeneration, but also as drug carriers...
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Gustav Oelsner i Hugo Althoff. W poszukiwaniu godnych warunków zamieszkania w Altonie i Gdańsku
PublikacjaCelem artykułu jest porównanie aktywności zawodowej dwóch architektów miejskich odpowiedzialnych za przestrzenny i architektoniczny rozwój Gdańska i Altony - Hugona Althoffa i Gustava Oelsnera, oraz porównanie architektury i urbanistyki modernistycznych osiedli socjalnych. Celem porównania jest zbadanie, w jakim stopniu lokalne uwarunkowania i tradycja mogą być nośnikiem uniwersalnych ideałów modernizmu i indywidualnej ekspresji...
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Acoustic streaming caused by some types of aperiodic sound. Buildup of acoustic streaming
PublikacjaThe analysis of streaming caused by aperiodic sound of different types (switched on at transducer sound or sound determined by initial conditions) is undertaken. The analysis bases on analytical governing equation for streaming Eulerian velocity, which is a result of decomposition of the hydrodynamic equations into acoustic and non-acoustic parts. Its driving force (of acoustic nature) represents a sum of two terms; one is the...
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Purification and biochemical characteristic of a cold-active recombinant esterase from Pseudoalteromonas sp. 643A under denaturing conditions.
PublikacjaIn this paper production of a cold-active esterase EstA from the Antarctic bacterium Pseudoalteromonas sp. 643A in E. coli expression system was described. The purification and biochemical characteristic of EstA were performed in the presence of urea and then compared with results obtained for the esterase with no addition of urea and isolated from the native source. In both cases the cold-active enzyme displayed similar properties....
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Cancer immune escape: the role of antigen presentation machinery
PublikacjaThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
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Analytical Study of Sliding Instability due to Velocity- and Temperature-Dependent Friction
PublikacjaThe instability of sliding causes deterioration of performance characteristics of tribosystems and is undesired. To predict its occurrence, the motion of a body of a one-degree-of-freedom system with friction is investigated about the steady sliding equilibrium position. The motion equation is formulated with the friction coefficient dependent on the sliding velocity and contact temperature changing due to transient heat conduction...
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Mining inconsistent emotion recognition results with the multidimensional model
PublikacjaThe paper deals with the challenge of inconsistency in multichannel emotion recognition. The focus of the paper is to explore factors that might influence the inconsistency. The paper reports an experiment that used multi-camera facial expression analysis with multiple recognition systems. The data were analyzed using a multidimensional approach and data mining techniques. The study allowed us to explore camera location, occlusions...
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Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.
PublikacjaEnterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). Acquisition of resistance determinants not only seriously limits available therapeutic options but also increases available gene pool for other species. It is believed that the recent evolution of two clinically relevant species, Enterococcus faecalis and Enterococcus faecium occurred...
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Poloxamer: A versatile tri-block copolymer for biomedical applications
PublikacjaPoloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers containing central hydrophobic chains of poly(propylene oxide) sandwiched between two hydrophilic chains of poly(ethylene oxide). Some chemical characteristics of poloxamers such as temperature-dependent self-assembly and thermo-reversible behavior along with biocompatibility and physiochemical properties make poloxamer-based biomaterials...
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Sequence-dependent structural properties of B-DNA: what have we learned in 40 years?
PublikacjaThe structure of B-DNA, the physiological form of the DNA molecule, has been a central topic in biology, chemistry and physics. Far from uniform and rigid, the double helix was revealed as a flexible and structurally polymorphic molecule. Conformational changes that lead to local and global changes in the helix geometry are mediated by a complex choreography of base and backbone rearrangements affecting the ability of the B-DNA...
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Electron mobility variance in semiconductors: the variance approach
PublikacjaPraca przedstawia nowe podejście da analizy zjawisk losowych w półprzewodnikach. Uwzględnia kilka mechanizmów zjawisk fluktuacji ruchliwości w półprzewodnikach, prowadzących do powstawamai składowej szumów typu 1/f, dominujących w zakresie małych czetotliwości. Przedstawia analizę sposobu wyznaczenia stałej Hooge'a określającej intensywność szumów typu 1/f.The statistical non-triviality of current carrier mobility fluctuations...
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Molecular Targets for Anticandidal Chemotherapy
PublikacjaA relatively small number of anticandidal chemotherapeutics used in clinical practice is at least in part consequence of a limited number of their molecular targets: ergosterol in the membrane, lanosterol demethylase, b(1!3) glucan synthase, and DNA/RNA biosynthesis. Much more potential novel targets have been revealed by the comparative genomic studies identifying essential genes unique for Candida albicans or resulted from recognition...
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Refined theoretical study of radiative association: Cross sections and rate constants for the formation of SiN
PublikacjaRadiative association of silicon mononitride (SiN) in its two lowest molecular electronic states is studied through quantum and classical dynamics. Special attention is paid to the behavior of the cross section at high collision energies. A modified expression for the semiclassical cross section is presented which excludes transitions to continuum states. This gives improved agreement with quantum mechanical perturbation theory...
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THE ARCHITECTURE OF DAYLIGHT IN THE DISCOURSE ABOUT THE AESTHETICS OF SUSTAINABILITY
PublikacjaThe need to create ecological and energy efficient architecture is evident today. In the contemporary discourse on architecture more and more attention is dedicated to the aesthetics that expresses the idea of sustainability. The article is a voice in this debate, concentrating on the architecture that features daylight. Solar light comes from the natural environment and brings some substantial benefits for the architectural space,...
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Versatility of putative aromatic aminotransferases from Candida albicans.
PublikacjaAmino acids constitute the key sources of nitrogen for growth of Candida albicans. In order to survive inside the host in different and rapidly changing environments, this fungus must be able to adapt via its expression of genes for amino acid metabolism. We analysed the ARO8, ARO9, YER152C, and BNA3 genes with regards to their role in the nutritional flexibility of C. albicans. CaAro8p is undoubtedly the most versatile enzyme...
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Estimating the uncertainty of discharge coefficient predicted for oblique side weir using Monte Carlo method
PublikacjaSide weir is a hydraulic structure, which is used in irrigation systems to divert some water from main to side channel. It is installed at the entrance of the side channel to control and measure passing water into the side channel. Many studies provided side weir water surface profile and coefficient of discharge to measure water discharge diverted into the side channel. These studies dealt with different side weir shapes (rectangular,...
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Design Equation for Stirring Fluid by a Stream Pump in a Circulating Tank
PublikacjaA circulating tank is a very useful theoretical scheme for many fluid-flow objects in several branches of engineering. The motion of the fluid in such objects can be induced in different ways. A stream pump provides an especially interesting possibility; however, the quantitative description of such devices shows some shortcomings. Such a device is analogous to a jet pump, thus has similar advantages (simplicity of construction,...
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Database of speech and facial expressions recorded with optimized face motion capture settings
PublikacjaThe broad objective of the present research is the analysis of spoken English employing a multiplicity of modalities. An important stage of this process, discussed in the paper, is creating a database of speech accompanied with facial expressions. Recordings of speakers were made using an advanced system for capturing facial muscle motion. A brief historical outline, current applications, limitations and the ways of capturing face...
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Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity
PublikacjaColorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this study, we synthesized a series of novel tetrahydroquinolinones and assessed their ability to inhibit CRC growth and proliferation by evoking...
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The Self-employment of Women in Azerbaijan
PublikacjaAzerbaijan has a population of more than 10 million, of which women accounted for 50% in 2020. At the same time, 93% of Azerbaijan’s citizens describe themselves as Muslims. Since the beginning of independence, Azerbaijan has been a secular state by virtue of Article 48 of the Constitution, which guarantees the freedom of worship, choice, or non-practice of religion and the freedom of...
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Environmental exposure to cadmium in breast cancer – association with the Warburg effect and sensitivity to tamoxifen
PublikacjaThe association between cadmium and breast cancer remains unexplained due to inconsistent epidemiological data and unknown underlying mechanisms. This study aimed to assess the relationship between environmental exposure to cadmium and the Warburg effect in breast cancer and, thus, its possible interference with breast cancer treatment. The observational study in two groups of breast cancer patients indicated a positive correlation between...
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Customizing nano-chitosan for sustainable drug delivery
PublikacjaChitosan is a natural polymer with acceptable biocompatibility, biodegradability, and mechanical stability; hence, it has been widely appraised for drug and gene delivery applications. However, there has been no comprehensive assessment to tailor-make chitosan cross-linkers of various types and functionalities as well as complex chitosan-based semi- and full-interpenetrating networks for drug delivery systems (DDSs). Herein, various...
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Specific detection of Alternaria alternata by PCR and real-time PCR
PublikacjaFungi of Alternaria genus are cosmopolitan organisms, which spores can be found in the air, soil, water, clothing and food. They commonly occur as saprotrophs on the plant remains, contributing to the decomposition of organic matter. Additionally, they are components of the normal human and animal skin flora. Alternaria spp. are also known human allergens, causing hay fever and allergic reactions that can lead to the development...
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PCR and real-time PCR assays to detect fungi of Alternaria alternata species
PublikacjaFungi of the Alternaria genus are mostly associated with allergic diseases. However, with a growing number of immunocompromised patients, these fungi, with A. alternata being the most prevalent one, are increasingly recognized as etiological agents of infections (phaeohyphomycoses) in humans. Nowadays, identification of Alternaria spp. requires their pure culture and is solely based on morphological criteria. Clinically, Alternaria...
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Implementation of FDTD-compatible Green's function on heterogeneous CPU-GPU parallel processing system
PublikacjaThis paper presents an implementation of the FDTD-compatible Green's function on a heterogeneous parallel processing system. The developed implementation simultaneously utilizes computational power of the central processing unit (CPU) and the graphics processing unit (GPU) to the computational tasks best suited to each architecture. Recently, closed-form expression for this discrete Green's function (DGF) was derived, which facilitates...
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WYRAŻANIE NIEDOKŁADNOŚCI POMIARU – BŁĄD CZY NIEPEWNOŚĆ?
PublikacjaMinęło ponad 20 lat od wprowadzenia dokumentu Guide to the Expression of Uncertainty in Measurements i Międzynarodowego słownika metrologii, w których to dokumentach przedstawiono odpowiednio metodologię wyznaczania niepewności pomiaru oraz terminologię metrologiczną. Współczesne liczne publikacje z tej tematyki w sztandarowych czasopismach metrologicznych dowodzą, że teoria ta na dobre zagościła w technice. Z tego względu w każdym...
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Network-aware Data Prefetching Optimization of Computations in a Heterogeneous HPC Framework
PublikacjaRapid development of diverse computer architectures and hardware accelerators caused that designing parallel systems faces new problems resulting from their heterogeneity. Our implementation of a parallel system called KernelHive allows to efficiently run applications in a heterogeneous environment consisting of multiple collections of nodes with different types of computing devices. The execution engine of the system is open for...
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The New Klebsiella pneumoniae ST152 Variants with Hypermucoviscous Phenotype Isolated from Renal Transplant Recipients with Asymptomatic Bacteriuria-Genetic Characteristics by WGS.
PublikacjaKlebsiella pneumoniae (Kp) is one of the most important etiological factors of urinary tract infections in renal transplant (RTx) recipients. We described the antimicrobial susceptibility phenotypes and genomic features of two hypermucoviscous (HM) Kp isolates recovered from RTx recipients with asymptomatic bacteriuria (ABU). Using whole genome sequencing (WGS) data, we showed that the strains belong to the ST152 lineage with the...
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Tailor-Made Polysaccharides for Biomedical Applications
PublikacjaPolysaccharides (PSAs) are carbohydrate-based macromolecules widely used in the biomedical field, either in their pure form or in blends/nanocomposites with other materials. The relationship between structure, properties, and functions has inspired scientists to design multifunctional PSAs for various biomedical applications by incorporating unique molecular structures and targeted bulk properties. Multiple strategies, such as...
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Biodiversity of microorganisms in the Baltic Sea: the power of novel methods in the identification of marine microbes
PublikacjaUntil recently, the data on the diversity of the entire microbial community from the Baltic Sea were relatively rare and very scarce. However, modern molecular methods have provided new insights into this field with interesting results. They can be summarized as follows. (i) Although low salinity causes a reduction in the biodiversity of multicellular species relative to the populations of the North–East Atlantic, no such reduction...
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Carbon Nanomaterials in Seed Priming: Current Possibilities
PublikacjaThe prevailing agricultural system has become deeply ingrained and insufficient due to outdated practices inherited from the Green Revolution, necessitating innovative approaches for sustainable agricultural development. Nanomaterials possess the potential to significantly improve the efficient utilization of resources while simultaneously encouraging sustainability. Among these, carbonaceous nanomaterials have found diverse applications...