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Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity
PublikacjaColorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this study, we synthesized a series of novel tetrahydroquinolinones and assessed their ability to inhibit CRC growth and proliferation by evoking...
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Design and evaluation of a base module of active power electronic transformer
PublikacjaThis paper presents an active power electronic transformer (APET) based on modular structure. The proposed three phase APET consists of at least three base modules (BM). The input/output stage of the BM is based on half-bridge sub modules. The isolation stage includes a medium frequency transformer and is realized as a dual half-bridge. The paper describes construction process and explains the control strategy. The theoretical...
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Design of a continuous intra-oral distraction device for mandibular bone
PublikacjaIn this paper we present example of a specific device used for distraction osteogenesis. Distraction osteogenesis (also called callus distraction, collotasis or osteodistraction) is a surgical process for reconstructing bone deformities or lengthening bones.
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Key success factors for small design offices in the bidding process
PublikacjaCompetition in the design office market is high, therefore it is important to be aware of the conditions determining the competitive advantage, thus increasing the bidding effectiveness. For this reason, the aim of the article is to identify key success factors (KSF) increasing successful bidding of a small design office. The factors were identified and then analysed based on a literature review, expert interviews and using Group...
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A comprehensive approach to SBR modelling for monitoring and control system design
PublikacjaThe aim of this research is to provide a comprehensive description of the Sequencing Batch Reactor (SBR) modelling for monitoring, control, and plant operational optimisation validation. The paper provides a detailed modelling of the SBR, its components and constituent processes. For this purpose, the mass balance principle and continuity equations were provided with a reactive term implemented using Activated Sludge Model (ASM)....
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Design and Optimization of a Compact Planar Radiator for UWB Applications and Beyond
PublikacjaA compact monopole antenna for ultra-wideband (UWB) and beyond applications has been proposed. The radiator is based on the monopole topology. The super-wideband behavior has been achieved using a combination of spline-based modifications applied to the driven element, as well as utilization of a tapered feed and a slot-modified ground plane. The electrical performance of the structure has been tuned using a numerical optimization...
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Model systemu zarządzania usługami według metodologii design-thinking
PublikacjaW literaturze przedmiotu brakuje jednoznacznych wskazań odnośnie decyzji o wyborze najbardziej odpowiedniego modelu projektowania usług, szczególnie w kontekście różnych uwarunkowań dla poszczególnych sektorów rynku. Opracowany algorytm umożliwia samodzielne rozwiązanie problemu doboru modelu wewnątrz organizacji, bez konieczności zatrudniania zewnętrznego specjalisty. Algorytm skierowany jest do organizacji w fazie przygotowawczej...
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Computer-Aided Automated Greenery Design—Towards a Green BIM
PublikacjaContemporary climate challenges are changing the architect’s awareness, which results in a broader spectrum of interest. The available software enables the design of vegetation, but it is often very limited and requires specialist knowledge. The available software allows the creation of individual solutions based on visual algorithms or writing scripts; however, they are still not common methods used in architecture and urban planning....
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Towards Rational Biosurfactant Design—Predicting Solubilization in Rhamnolipid Solutions
PublikacjaThe efficiency of micellar solubilization is dictated inter alia by the properties of the solubilizate, the type of surfactant, and environmental conditions of the process. We, therefore, hypothesized that using the descriptors of the aforementioned features we can predict the solubilization efficiency, expressed as molar solubilization ratio (MSR). In other words, we aimed at creating a model to find the optimal surfactant and...
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Design of poroelastic wearing course with the use of direct shear test
PublikacjaPoroelastic Road Surfaces (PERS) are characterized by porous structure with at least 20% of air void content and stiffness almost 10 times lower than typical asphalt course. Such properties enable noise reduction up to 12 dB in comparison to SMA 11 mixture. However, the main disadvantage of previously used poroelastic mixtures, based on resin type binders, was their low durability, which resulted in raveling and delamination from...
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Architecture Design of a Networked Music Performance Platform for a Chamber Choir
PublikacjaThis paper describes an architecture design process for Networked Music Performance (NMP) platform for medium-sized conducted music ensembles, based on remote rehearsals of Academic Choir of Gdańsk University of Technology. The issues of real-time remote communication, in-person music performance, and NMP are described. Three iterative steps defining and extending the architecture of the NMP platform with additional features to...
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The methodology of design of satellite working mechanism of positive displacement machine
PublikacjaIn this paper is described a methodology of design of satellite mechanism consisting of two noncircular gears (externally toothed rotor and internally toothed curvature) and circular gears (satellites). In the presented methodology is assumed that the rotor pitch line is known, and the curvature pitch line is necessary to designate. The presented methodology applies to mechanisms for which the number of the curvature humps is at...
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Design of weighted PID controllers for control of the Stewart-Gough platform
PublikacjaStewart-Gough platform (SGP) is a popular parallel type manipulator that involves a 6 degrees of freedom (DOF) motion. In this paper, the process of mathematical modelling of SGP is presented. Two selected control algorithms that use PID controllers and weighted PID controllers are designed. Both control systems using these algorithms are implemented in MATLAB environment as well as on the actual SGP. Parameters of the controllers...
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Lighting Design for the 21st Century Applied research in lighting practice
PublikacjaFor those who are unfamiliar with research, it’s important to know there are two categories. Fundamental (or basic) research and applied research. Basic research often discusses scientific ideas/theories, whereas, applied research explores testing these ideas in practice to develop technology or techniques. It’s applied research which most interests lighting practitioners. Great lighting design that creates a pleasant and beneficial...
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Study on the accuracy of axle load spectra used for pavement design
PublikacjaWeigh-in-Motion (WIM) systems are used in order to reduce the number of overloaded vehicles. Data collected from WIM provide characteristics of vehicle axle loads that are crucial for pavement design as well as for the development of pavement distress prediction models. The inaccuracy of WIM data lead to erroneous estimation of traffic loads and in consequence inaccurate prediction of pavement distress process. The objective of...
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Electromagnetic Simulation with 3D FEM for Design Automation in 5G Era
PublikacjaElectromagnetic simulation and electronic design automation (EDA) play an important role in the design of 5G antennas and radio chips. The simulation challenges include electromagnetic effects and long simulation time and this paper focuses on simulation software based on finite-element method (FEM). The state-of-the-art EDA software using novel computational techniques based on FEM can not only accelerate numerical analysis, but...
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Freehand drawing versus digital design tools in architectural teaching
PublikacjaThe oldest drawings resembling modern architectural designs date from the 22nd Century BC. Throughout history, the first drawings have evolved into the basic tool of the architect’s work. The exchange of information between the architect and the contractor began to take place through a drawing system, allowing to describe three-dimensional space using flat representations. With time, architectural drawings also began to resemble...
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Fatigue and Metabolic Responses during Repeated Sets of Bench Press Exercise to Exhaustion at Different Ranges of Motion
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Recent advances in reinforced bioplastics for food packaging – A critical review
PublikacjaRecently, diversifying the material, method, and application in food packaging has been massively developed to find more environment-friendly materials. However, the mechanical and barrier properties of the bioplastics are major hurdles to expansion in commercial realization. The compositional variation with the inclusion of different fillers could resolve the lacking performance of the bioplastic. This review summarizes the various...
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Design of Analog Filters with Single Transmission Zeros, Dedicated for HFB Systems
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A review of rare earth oxides-based photocatalysts: Design strategies and mechanisms
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Design and Utility of Specialist Comminution Set-Up for Plastics and Organic Materials
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Issues Regarding the Design of Textile Compression Products for Small Body Circumferences
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Design and Thermodynamic Analysis of an SOFC System for Naval Surface Ship Application
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Comparison of Seepage Models Applied to Design of Trapezoidal Infiltration Trenches and Basins
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Design of Compact and Wideband Groove Gap Waveguide-Based Directional Couplers
PublikacjaThis paper proposes a compact cross-shaped groove gap waveguide structure for creating wideband and compact directional couplers with different coupling levels. Groove gap waveguide technology is applied to overcome fabrication challenges of printed and hollow waveguide structures in high frequency bands. The validity of the novel concept is demonstrated through the design and evaluation of several compact broadband directional...
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Wireless Charging Station Design for Electric Scooters: Case Study Analysis
PublikacjaThis study proposes an example of a wireless charging station design for a small-scale vehicle available on the market. The article analyzes basic transmitter inverter topologies and their compensation methods in terms of flexibility of control, tolerance to uncertainty in positioning, and the possibility of decreasing the integration price. Our comprehensive analysis focuses on the battery voltage range, energy capacity, cost,...
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Design and Evaluation of the Compact and Autonomous Energy Subsystem of a Wave Energy Converter
PublikacjaThis paper presents the results of the design process focused on the development of the energy subsystem (ES) of a wave energy converter (WEC). The ES is an important electrical part that significantly affects the energy reliability and energy efficiency of the entire WEC device. The designed ES was intended for compact WECs powering IoT network devices working in the distributed grid. The developed ES is an electronic circuit...
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Hierarchical dynamic hybrid models for aided design of ship power subsystems.
PublikacjaRozważa się wielopoziomowe modele systemu energetycznego statku. Elementy systemu są modelowane z użyciem ciągłych zmiennych stanu i uwzględnieniem zerowego związku przyczynowo-skutkowego. Poziom pierwszy opisuje wzajemne związki modeli zerowego poziomu, poziom drugi reprezentuje powiązania modeli pierwszego poziomu itd. W ten sposób opisuje się modele elementów zespołów i podsystemów. Każdy z modeli może być hybrydowym modelem...
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Design of synchronous generator voltage regulator based on h control theory
PublikacjaThe power system is highly nonlinear system, which dynamics depends on system network configuration, system loading…etc. To overcome the above mentioned difficulties and to fulfill the performance requirements the different control methods are considered and tested for application to generating control unit. Application of the H optimization method to automatic voltage regulator is studied in this paper. Simulation results have...
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Design and measurement of gyrator and isolator using ferrite coupled microstrip lines
PublikacjaW publikacji przeprowadzono badania struktur żyratora i izolatora zrealizowanych w technice sprzężonych ferrytowych linii mikropaskowych. Po raz pierwszy zaprezentowano wyniki pomiaru zrealizowanych struktur tego rodzaju. Uzyskane wyniki potwierdzają przewidziany uprzednio efekt zmian kierunków działania opisywanych elementów ze zmianą częstotliwości.
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Novel structure and design of enhanced-bandwidth hybrid quadrature patch coupler
PublikacjaA novel structure and design optimization procedure of an enhanced-bandwidth hybrid quadrature patch coupler is proposed. Improved performance of the circuit has been obtained by parameterizing the coupler sections using splines, which introduces additional degrees of freedom. Due to computational complexity of the parameter adjustment problem, a sequential design procedure is applied. In each iteration, a selected number of spline...
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Hybrid Expert System for Computer-Aided Design of Ship Thruster Subsystems
PublikacjaThe article presents an expert system supporting the design of ship's power subsystems, in particular the thruster subsystem. The proposed hybrid expert system uses the results of simulation tests as the additional source of knowledge. The results of system operation are collated in a report which can be used as part of ship design description. The work oriented on developing the expert system is the continuation of the research...
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Design solution and selected research results of the sea-wave energy converter
PublikacjaW artykule przedstawiono oryginalne rozwiązanie konstrukcyjne boi do pozyskiwania energii fal morskich oraz analizy i badania modelowe turbiny wodnej poprzedzające wybór ostateczny konstrukcji modelu boi w skali 1:5 przewidzianego do badań eksperymentalnych w basenie holowniczym. Zaprezentowano także wybrane wyniki badań modelowych i symulacji komputerowych ukazujący wpływ systemu kotwiczenia i innych parametrów na jakość i efektywność...
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Rapid antenna design optimization using shape-preserving response prediction
PublikacjaAn approach to rapid optimization of antennas using the shape-preserving response-prediction (SPRP) technique and coarsediscretization electromagnetic (EM) simulations (as a low-fidelity model) is presented. SPRP allows us to estimate the response of the high-fidelity EM antenna model, e.g., its reflection coefficient versus frequency, using the properly selected set of so-called characteristic points of the low-fidelity model...
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Design of synchronous generator voltage regulator based on H control theory
PublikacjaSystemy dużej mocy są z reguły systemami o dużej nieliniowości. Wynika to z dynamiki takiego obiektu jak również jego konfiguracji itd. Istnieje wiele metod umożliwiających sterowanie czy testowanie zaprojektowanych generatorów. W artykule analizowana jest metoda projektowania regulatora napięcia w oparciu o H. Wyniki symulacji są zadowalające, ponieważ tak zaprojektowany regulator lepiej tłumi kołysania elektromechaniczne niż...
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The design of the prosthetic index finger actuated by shape memory alloy wires
PublikacjaZaprezentowano projekt palca wskazującego protezy ręki, w którym poszczególne człony napędzane są za pomocą niekonwencjonalnych efektorów - stopów metali z pamięcią kształtu (SMA - NiTi).
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Coupled - mode design of ferrite loaded coupled microstrip lines section
PublikacjaMetodę rodzajów sprzężonych zastosowano do analizy i projektowania sekcji ferrytowych mikropaskowych linii sprzężonych magnesowanych podłużnie (FCL). W wyniku analizy określono macierz rozproszenia sekcji oraz warunki umożliwiające jej zastosowanie do realizacji cyrkulatora projetowanego jako połączenie badanej sekcji FCL z mikropaskowym rozgałęzieniem typu T. W oparciu o opracowane oprogramowanie przeprowadzono modelowanie parametrów...
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Design of highly linear tunable CMOS OTA for continuous-time filters
PublikacjaW pracy przedstawiono analityczną metodę projektowania wzmacniaczy transkon-duktancyjnych CMOS o bardzo dobrej liniowości. Zaproponowano dwie wersje układu różniące się umiejscowieniem dodatkowej pary różnicowej służącej do kompensacji nieliniowości charakterystyki przejściowej. Praca zawiera wyniki symulacji pełnych wersji obu układów otrzymane przy użyciu symulatora SPICE.
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Robust design in delta domain for SISO plants: PI and PID controllers
PublikacjaW pracy przedstawiono zunifikowaną metodę numerycznie odpornej syntezy sterowników (regulatorów) działających w dyskretnym czasie w układach sterowania skalarnymi obiektami czasu ciągłego. Wykorzystano dyskretnoczasowe modele takich obiektów, oparte na tak zwanym operatorze delta, charakteryzującym się korzystnymi odpornościowymi cechami w przypadku stosowania dostatecznie małych wartości okresu próbkowania przetwarzanych sygnałów....
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User-oriented GIS tools in higher education of urban design and planning
PublikacjaGeographic information systems (GIS) have emerged as indispensable tools for decision-making, planning and problem-solving tasks across various domains in today’s evolving world. However, there exists a pressing need to augment the utilisation of GIS tools in higher education of urban design and planning to foster a user-oriented approach. This article explores the imperative of integrating GIS tools more comprehensively into higher...
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Low temperature rotary Stirling engine: conceptual design and theoretical analysis
PublikacjaThe use of low-temperature energy sources for electricity generation demands a dual focus: a substantial enhancement in the efficiency of energy conversion devices and a reduction in system production costs. Particularly in scenarios where low-temperature energy sources are scarce, this factor can be pivotal in facilitating widespread adoption of such technologies. The Stirling engine emerges as a promising solution capable of...
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Leveraging Generative AI Tools for UX Design in Lean and Agile Projects
PublikacjaRecent advancements in Generative AI (GenAI) open new opportunities to improve User Experience (UX) practitioners’ efficiency in their projects. Due to intensive teamwork caused by time pressure and readiness for rapid changes, Lean and Agile project management seems particularly predestined for easy adoption of GenAI-supported UX design methods. However, precipitate and spontaneous leveraging of GenAI tools to UX design bears...
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Study the impact of design method preference on the usefulness of concrete and on CO2 emissions
PublikacjaPurpose – The research investigates the impact of concrete design methods on performance, emphasizing environmental sustainability. The study compares the modified Bolomey method and Abrams’ law in designing concretes. Significant differences in cement consumption and subsequent CO2 emissions are revealed. The research advocates for a comprehensive life cycle assessment, considering factors like compressive strength, carbonation...
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Optimal Components Design for Modified Z-Source Based IPT Approach
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Asymptotic modelling and design of some microlayered functionally graded heat conductors
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Design of dimensionally stable composites using efficient global optimization method
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Mechatronic design for the high speed milling surveillance of the complex and flexible details
PublikacjaW pracy przedstawiono mechatroniczny system tworzenia mapy optymalnych prędkości obrotowych wrzeciona. W trakcie frezowania szybkościowego przedmiotów podatnych mogą wystąpić drgania samowzbudne typu chatter. Używana zazwyczaj procedura ustawiania wymaganej prędkości obrotowej wrzeciona metodą prób i błędów, w wielu przypadkach nie jest zalecana. Przedstawiona procedura nadzorowania może doprowadzić do uniknięcia ryzyka wystąpienia...
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3rd International Workshop on Reliable Networks Design and Modeling (RNDM 2011)
Publikacjaartykuł sprawozdawczy z konferencji
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Gain deficit effect in the fractional delay filter design by the window method
PublikacjaMetoda okien jest sposobem szybkiego i skutecznego projektowania filtrów ułamkowoopóźniających. Jednakże wzmocnienie tak zaprojektowanego filtru różni się od zakładanej wartości idealnej. To zjawisko, nazywane deficytem wzmocnienia, negatywnie wpływa na jakoś projektowanego filtru. Artykuł poświęcono wynikom badań oraz metodom korekcji tego problemu. Omówiono wpływ współczynnika korekcji deficytu wzmocnienia na charakterystykę...