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Rating by detection: an artifact detection protocol for rating EEG quality with average event duration
PublikacjaQuantitative evaluation protocols are critical for the development of algorithms that remove artifacts from real EEG optimally. However, visually inspecting the real EEG to select the top-performing artifact removal pipeline is infeasible while hand-crafted EEG data allow assessing artifact removal configurations only in a simulated environment. This study proposes a novel, principled approach for quantitatively evaluating algorithmically...
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The influence of Nigella sativa essential oil on proliferation, activation, and apoptosis of human T lymphocytes in vitro
PublikacjaIn previous work, we tested the immunomodulatory effect of Nigella sativa (NS) fatty oil. Our results demonstrated that unrefined, obtained by cold pressing black cumin seed oil inhibited lymphocytes’ proliferation and induced their apoptosis in a dose-dependent manner. In this study, we examined the immunomodulatory properties of essential oil (EO) obtained from the NS seeds by hydrodistillation and its two main constituents:...
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Acid–Base Equilibrium and Self-Association in Relation to High Antitumor Activity of Selected Unsymmetrical Bisacridines Established by Extensive Chemometric Analysis
PublikacjaUnsymmetrical bisacridines (UAs) represent a novel class of anticancer agents previously synthesized by our group. Our recent studies have demonstrated their high antitumor potential against multiple cancer cell lines and human tumor xenografts in nude mice. At the cellular level, these compounds affected 3D cancer spheroid growth and their cellular uptake was selectively modulated by quantum dots. UAs were shown to undergo metabolic...
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A note on the applications of artificial intelligence in the hospitality industry: preliminary results of a survey
PublikacjaIntelligent technologies are widely implemented in different areas of modern society but specific approaches should be applied in services. Basic relationships refer to supporting customers and people responsible for services offering for these customers. The aim of the paper is to analyze and evaluate the state-of-the art of artificial intelligence (AI) applications in the hospitality industry. Our findings show that the major...
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Potential of Silver Nanoparticles in Overcoming the Intrinsic Resistance of Pseudomonas aeruginosa to Secondary Metabolites from Carnivorous Plants
PublikacjaCarnivorous plants are exemplary natural sources of secondary metabolites with biological activity. However, the therapeutic antimicrobial potential of these compounds is limited due to intrinsic resistance of selected bacterial pathogens, among which Pseudomonas aeruginosa represents an extreme example. The objective of the study was to overcome the intrinsic resistance of P. aeruginosa by combining silver nanoparticles (AgNPs)...
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Two-step mechanism of J-domain action in driving Hsp70 function
PublikacjaJ-domain proteins (JDPs), obligatory Hsp70 cochaperones, play critical roles in protein homeostasis. They promote key allosteric transitions that stabilize Hsp70 interaction with substrate polypeptides upon hydrolysis of its bound ATP. Although a recent crystal structure revealed the physical mode of interaction between a J-domain and an Hsp70, the structural and dynamic consequences of J-domain action once bound and how Hsp70s...
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Reliable Surrogate Modeling of Antenna Input Characteristics by Means of Domain Confinement and Principal Components
PublikacjaA reliable design of contemporary antenna structures necessarily involves full-wave electromagnetic (EM) analysis which is the only tool capable of accounting, for example, for element coupling or the effects of connectors. As EM simulations tend to be CPU-intensive, surrogate modeling allows for relieving the computational overhead of design tasks that require numerous analyses, for example, parametric optimization or uncertainty...
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Machine Learning Techniques in Concrete Mix Design
PublikacjaConcrete mix design is a complex and multistage process in which we try to find the best composition of ingredients to create good performing concrete. In contemporary literature, as well as in state-of-the-art corporate practice, there are some methods of concrete mix design, from which the most popular are methods derived from The Three Equation Method. One of the most important features of concrete is compressive strength, which...
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Rapid Re-Design and Bandwidth/Size Trade-Offs for Compact Wideband Circular Polarization Antennas Using Inverse Surrogates and Fast EM-Based Parameter Tuning
PublikacjaDesign of compact wideband circularly polarized (CP) antennas is challenging due to the necessity of simultaneous handling of several characteristics (reflection, axial ratio, gain) while maintaining a small size of the structure. Antenna re-design for various operating bands is clearly more difficult yet practically important because intentional reduction of the bandwidth (e.g., by moving the lower edge of the operating band up...
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Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data
PublikacjaThe field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging methods. Liquid biopsies allow studying of tumor-derived markers in bodily fluids, enabling the development of more precise cancer diagnostic tests for screening, disease monitoring, and...
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Usability of Mobile Applications: A Consolidated Model
PublikacjaMobile devices have become an integral part of the digital ecosystem, connecting people, businesses, and information around the world in ways never before possible. In particular, smartphones, tablets and other handheld devices equipped with mobile applications have changed every aspect of our lives. Today, a user can choose from nearly five million applications available for both Android and iOS operating systems. However, only...
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Use of structural equation modeling in quantitative research in the field of management and economics: A bibliometric analysis in the systematic literature review
PublikacjaPURPOSE: This paper aims to provide a comprehensive review of scholarly research focusing on using quantitative methods and particularly structural equation modeling (SEM) in management and economics studies, as well as provide a bibliometric agenda including the time horizon of individual publications, the highest citation rate, geographic and industry areas, methodological context, and keywords. METHODOLOGY: A systematic literature...
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The UK's banking system as financial hub for Islamic banking
PublikacjaThis paper examines the phenomenon of London as "the Islamic banking hub". It contends that London has become not only an international centre for Islamic finance, but also that there is big interest and demand for Islamic banking products. The authors are also positive that Islamic banking may be a certain solution for the problems that Europe has been suffering since 2007 when the global debt crisis started. Our intention is...
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Informal employment in Poland: an empirical spatial analysis
PublikacjaThe main goal of our article is to bridge the gap in the regional analysis of informal employment in Poland and in particular to indicate the propensity for informal work in the working-age population, to test if informal activities are typical for marginalized people (less educated, unemployed, older) and to identify the regional and spatial heterogeneity in the propensity. We use data from the ‘Human Capital Balance 2010–2014’...
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Fast Multi-Objective Antenna Design Through Variable-Fidelity EM Simulations
PublikacjaA technique for fast multi-objective antenna optimization is introduced. A kriging interpolation surrogate constructed from sampled coarse-mesh EM simulations is utilized by multi-objective evolutionary algorithm (MOEA) to obtain the initial Pareto front approximation. The surrogate is defined in a subset of the original design space, determined by means of independently optimized individual objectives. Response correction techniques...
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Novel Structure and EM-Driven Design of Small UWB Monopole Antenna
PublikacjaA novel structure of a small UWB monopole antenna is presented. In our approach, a compact size is achieved by means of a meander line for current path enlargement as well as the two parameterized slits that introduce additional degrees of freedom helping to ensure good impedance matching. The antenna design is carried out using surrogate-based optimization involving variable-fidelity EM simulations. This allows us to simultaneously...
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A quaternion-based modified feistel cipher for multimedia transmission
PublikacjaIn this paper a quaternion-based modified Feistel Cipher is proposed. The algorithm is based on the scheme proposed by Sastry and Kumar (2012). Our algorithm uses special properties of quaternions to perform rotations of data sequences in 3D space for each of the cipher rounds. The plaintext (image in gray-tone) is divided into two square matrices of equal size which consist of Lipschitz quaternions. A modular arithmetic was implemented...
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Pathological brain network activity: memory impairment in epilepsy
PublikacjaOur thinking, memory and cognition in general, relies upon precisely timed interactions among neurons forming brain networks that support cognitive processes. The surgical evaluation of drug-resistant epilepsy using intracranial electrodes provides a unique opportunity to record directly from human brain and to investigate the coordinated activity of cognitive networks. In this issue of Neurology®, Kleen and colleagues1 implicate...
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The possibility of use keratin products in various branches of industry
PublikacjaBird's feather, the main by-product of the poultry industry, are not enough utilized and negatively influencing the environment. They contain large amount of keratin, the protein with high cystine content. The aim of our work was to obtain hydrolysates and isolates of keratin, which can be used in various areas of food, cosmetics, pharmaceutical industry and as animal feed. Keratin can be hydrolyzed and extracted from feather after...
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On neutral differential equations and the monotone iterative method
PublikacjaThe application of the monotone iterative method to neutral differential equations with deviating arguments is considered in this paper. We formulate existence results giving sufficient conditions which guarantee that such problems have solutions. This approach is new and to the Authors' knowledge, this is the first paper when the monotone iterative method is applied to neutral first-order differential equations with deviating...
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Detection of Polish clinical Aspergillus fumigatus isolates resistant to triazoles
PublikacjaWe studied the presence of triazole resistance of 121 Aspergillus fumigatus clinical isolates collected in two Polish cities, Warsaw and Wrocław, to determine if resistance is emerging in our country. We identified five itraconazole resistant isolates (4.13%) carrying the TR34/L98H alteration in Cyp51A gene, four of which were cross-resistant to posaconazole and one to voriconazole. One isolate was intermediate susceptible to itraconazole...
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Numerical Studies on Propellers in Open Water and behind Hulls aiming to support the Evaluation of Propulsion Tests
PublikacjaA RANS based numerical analysis of propellers can contribute considerably to our understanding of propeller/hull interaction. It may also allow for a review of scaling procedures on results from experimental fluid dynamics (EFD). Using various RANS codes (Fluent, CFX, STAR-CCM+ and FreSCo+) on common test cases the authors first focused on propeller open water (POW) calculations. Next we simulated the propeller hull interaction...
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Reducing income inequalities through government expenditures on education. Evidence for European countries Piotr PłatkowskiORCID Icon &Ewa LechmanORCID Icon
PublikacjaThis study examines the role of government spending on education in mitigating income inequalities. The study uses dynamic panel regressions to assess the evolution of education expenditures and income inequality in the sample of 30 European countries between 1995 and 2018. Our findings show that increases in government spending on education positively affect income inequality reduction. The impact was more substantial in case...
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Existence and uniqueness of solutions for single-population McKendrick-von Foerster models with renewal
PublikacjaWe study a McKendrick-von Foerster type equation with renewal. This model is represented by a single equation which describes one species which produces young individuals. The renewal condition is linear but takes into account some history of the population. This model addresses nonlocal interactions between individuals structured by age. The vast majority of size-structured models are also treatable. Our model generalizes a number...
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Optimization of the System for Determining the Volume of Tissue Needed for Breast Reconstruction
PublikacjaThis article presents techniques for reconstructing surfaces and volume calculations using a point cloud generated from 3D imaging. The main objective of this article was to optimize the voxel size for the most accurate representation of the surface of the female breast. We experimented with different methods for determining volume using images from the Intel D435i camera. In addition, we designed application and measurement station...
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Extendable Safety and Security Ontology
PublikacjaSecurity plays an increasingly important role in our everyday life, and research and users of computer systems point out that the need arises for a common, formalised model capable of integrating different solutions. In this paper we show that an ontology can be designed and created in a way that will make it suitable for interoperability and integration. A security and safety ontology and the methodology for creating a common...
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Mobile operators at war: opinion mining and sentiment analysis on social media
PublikacjaConsidering hermetic and very competitive market such as mobile operator ones, social media has become best alternative for contact with customer and gathering data and opinions. Different style of running social media profiles is giving different results. The research presented in this paper aims to show the number of responses gathered from polish Internet users and its sentiment for mobile operator brands. It also presents practical...
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Superconductivity in Bismuth Pyrochlore Lattice Compounds RbBi2 and CsBi2: The Role of Relativistic Effects
PublikacjaSuperconducting properties of two bismuthide intermetallic compounds, RbBi2 and CsBi2, were studied by means of experimental measurements and ab initio calculations. We show that in both compounds, the superconductivity emerges from the pyrochlore Bi lattice and its formation is heavily influenced by relativistic effects. Based on our analysis of the effect of spin–orbit coupling on the electron–phonon coupling, we suggest a possible...
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Gdańsk palimpsest. On obscuring and retrieving traces of memory
PublikacjaThe article deals with the problems of collective identity resulting from over one thousand year history of the city on the Motława river and the role of historical policy of the local authorities regarding the material cultural heritage of many nations and cultures. In our opinion, the palimpsestic (palimpsestueuse) character of the city plays a significant role in the discourse about the past of Gdańsk. We use that notion after...
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Quantum communication complexity advantage implies violation of a Bell inequality
PublikacjaWe obtain a general connection between a quantum advantage in communication complexity and non-locality. We show that given any protocol offering a (sufficiently large) quantum advantage in communication complexity, there exists a way of obtaining measurement statistics which violate some Bell inequality. Our main tool is port-based teleportation. If the gap between quantum and classical communication complexity can grow arbitrarily...
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Multiple Solutions to Third-Order Differential Equations with Derivative Dependence and Deviating Arguments
PublikacjaIn this paper, we give some new results for multiplicity of positive (nonnegative) solutions for third-order differential equations with derivative dependence, deviating arguments and Stieltjes integral boundary conditions. We discuss our problem with advanced argument α and arbitrary β ∈ C([0,1],[0,1]), see problem (2). It means that argument β can change the character on [0,1], so β can be delayed in some set J ⊂ [0,1] and advanced...
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EM-Driven Multi-Objective Design of Impedance Transformers By Pareto Ranking Bisection Algorithm
PublikacjaIn the paper, the problem of fast multi-objective optimization of compact impedance matching transformers is addressed by utilizing a novel Pareto ranking bisection algorithm. It approximates the Pareto front by dividing line segments connecting the designs found in the previous iterations, and refining the obtained candidate solutions by means of poll-type search involving Pareto ranking. The final Pareto set is obtained using...
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Reconfiguring Minimum Dominating Sets in Trees
PublikacjaWe provide tight bounds on the diameter of γ-graphs, which are reconfiguration graphs of the minimum dominating sets of a graph G. In particular, we prove that for any tree T of order n ≥ 3, the diameter of its γ-graph is at most n/2 in the single vertex replacement adjacency model, whereas in the slide adjacency model, it is at most 2(n − 1)/3. Our proof is constructive, leading to a simple linear-time algorithm for determining...
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Towards Extending Wikipedia with Bidirectional Links
PublikacjaIn this paper, we present the results of our WikiLinks project which aims at extending current Wikipedia linkage mechanisms. Wikipedia has become recently one of the most important information sources on the Internet, which still is based on relatively simple linkage facilities. A WikiLinks system extends the Wikipedia with bidirectional links between fragments of articles. However, there were several attempts to introduce bidirectional...
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Universal construction of genuinely entangled subspaces of any size
PublikacjaWe put forward a simple construction of genuinely entangled subspaces – subspaces supporting only genuinely multipartite entangled states – of any permissible dimensionality for any number of parties and local dimensions. The method uses nonorthogonal product bases, which are built from totally nonsingular matrices with a certain structure. We give an explicit basis for the constructed subspaces. An immediate consequence of our...
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Implementation of Coprocessor for Integer Multiple Precision Arithmetic on Zynq Ultrascale+ MPSoC
PublikacjaRecently, we have opened the source code of coprocessor for multiple-precision arithmetic (MPA). In this contribution, the implementation and benchmarking results for this MPA coprocessor are presented on modern Zynq Ultrascale+ multiprocessor system on chip, which combines field-programmable gate array with quad-core ARM Cortex-A53 64-bit central processing unit (CPU). In our benchmark, a single coprocessor can be up to 4.5 times...
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Subharmonic solutions for a class of Lagrangian systems
PublikacjaWe prove that second order Hamiltonian systems with a potential of class C1, periodic in time and superquadratic at infinity with respect to the space variable have subharmonic solutions. Our intention is to generalise a result on subharmonics for Hamiltonian systems with a potential satisfying the global Ambrosetti-Rabinowitz condition from [P. H. Rabinowitz, Proc. Roy. Soc. Edinburgh Sect. A, 114 (1990), 33-38]. Indeed, we weaken...
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Rendezvous of Distance-Aware Mobile Agents in Unknown Graphs
PublikacjaWe study the problem of rendezvous of two mobile agents starting at distinct locations in an unknown graph. The agents have distinct labels and walk in synchronous steps. However the graph is unlabelled and the agents have no means of marking the nodes of the graph and cannot communicate with or see each other until they meet at a node. When the graph is very large we want the time to rendezvous to be independent of the graph size...
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Long-distance quantum communication over noisy networks without long-time quantum memory
PublikacjaThe problem of sharing entanglement over large distances is crucial for implementations of quantum cryptography. A possible scheme for long-distance entanglement sharing and quantum communication exploits networks whose nodes share Einstein-Podolsky-Rosen (EPR) pairs. In Perseguers et al. [Phys. Rev. A 78, 062324 (2008)] the authors put forward an important isomorphism between storing quantum information in a dimension D and transmission...
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Surrogate-assisted EM-driven miniaturization of wideband microwave couplers by means of co-simulation low-fidelity models
PublikacjaThis article proposes a methodology for rapid design optimization of miniaturized wideband couplers. More specifically, a class of circuits is considered, in which conventional transmission lines are replaced by their abbreviated counterparts referred to as slow-wave compact cells. Our focus is on explicit reduction of the structure size as well as on reducing the CPU cost of the design process. For the sake of computational feasibility,...
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Torsional elasticity and energetics of F1-ATPase
PublikacjaFoF1-ATPase is a rotary motor protein synthesizing ATP from ADP driven by a cross-membrane proton gradient. The proton flow through the membrane-embedded Fo generates the rotary torque that drives the rotation of the asymmetric shaft of F1. Mechanical energy of the rotating shaft is used by the F1 catalytic subunit to synthesize ATP. It was suggested that elastic power transmission with transient storage of energy in some compliant...
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TaRh 2 B 2 and NbRh 2 B 2 : Superconductors with a chiral noncentrosymmetric crystal structure
PublikacjaIt is a fundamental truth in solid compounds that the physical properties follow the symmetry of the crystal structure. Nowhere is the effect of symmetry more pronounced than in the electronic and magnetic properties of materials—even the projection of the bulk crystal symmetry onto different crystal faces is known to have a substantial impact on the surface electronic states. The effect of bulk crystal symmetry on the properties...
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Novel approach to modeling spectral-domain optical coherence tomography with Monte Carlo method
PublikacjaNumerical modeling Optical Coherence Tomography (OCT) systems is needed for optical setup optimization, development of new signal processing methods and assessment of impact of different physical phenomena inside the sample on OCT signal. The Monte Carlo method has been often used for modeling Optical Coherence Tomography, as it is a well established tool for simulating light propagation in scattering media. However, in this method...
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Inhibiting activity of HIV-1: protease, reverse transcriptase and integrase all together by novel compounds using computational approaches (flexible and rigid docking)
PublikacjaAcquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus type 1 (HIV-1) infection, is one of the most challenging diseases in recent decades. Nevertheless the shortcomings of chemical drugs such as toxicity, lack of curative effects, the search for more potent anti-HIV agents have been focused in our study. In current study, novel scaffold was designed having a benzyl and imidazole in it which are very...
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Low to intermediate energy elastic electron scattering from dichloromethane (CH2Cl2)
PublikacjaWe report a theoretical-experimental investigation of electron scattering by dichloromethane (CH2Cl2) in the low- and intermediate energy ranges. Experimental elastic differential cross sections (DCS), in the incident electron energy range of 0.5-800 eV and scattering angle range of 10°–130°, were measured using a crossed beam relative flow technique. Integral and momentum- transfer cross sections were determined from the experimental...
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The Housing Pattern and Entrepreneurship in Polish Suburban Landscape
PublikacjaAbstract. Housing stimulates the development of SMEs (small and medium enterprises) in the suburbs. The multidisciplinary research in fields of urban planning and economics, carried out by the Authors, confirms this trend. The purpose of this paper is to present the multidisciplinary results of the research on the determinants of SME localization in the suburban areas of Gdansk, Gdynia and Sopot (the Metropolitan Area Gdansk–Gdynia-Sopot...
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TINKTEP: A fully self-consistent, mutually polarizable QM/MM approach based on the AMOEBA force field
PublikacjaWe present a novel quantum mechanical/molecular mechanics (QM/MM) approach in which a quantum subsystem is coupled to a classical subsystem described by the AMOEBA polarizable force field. Our approach permits mutual polarization between the QM and MM subsystems, effected through multipolar electrostatics. Self-consistency is achieved for both the QM and MM subsystems through a total energy minimization scheme. We provide an expression...
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Driving forces of informal employment: An empirical study based on Polish enterprise data
PublikacjaObjective: The article aims to indicate the determinants of informal employment in registered enterprises using company-level evidence from Poland. Research Design & Methods: The survey conducted among Polish small and medium-sized (SME) enterprises in 2018 was used to find the driving forces of informal employment in Poland. The adequate sample comprised 952 representative surveys derived from the computer-assisted telephone...
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Efficient production of Staphylococcus simulans lysostaphin in a benchtop bioreactor by recombinant Escherichia coli.
PublikacjaLysostaphin is an enzyme with bactericidal activity against Staphylococcus aureus and other staphylococcal species. In spite of many advantages and promising results of preliminary research, the enzyme is still not widely used in medicine, veterinary or as a food preservative. One of the most important factors limiting application of the enzyme in clinical or technological practice is the high costs of its production. In the present...
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In vitro enzyme kinetics and NMR-based product elucidation for glutathione S-conjugation of the anticancer unsymmetrical bisacridine C-2028 in liver microsomes and cytosol: major role of glutathione S-transferase M1-1 isoenzyme
PublikacjaThis work is the next step in studying the interplay between C-2028 (anticancer-active unsymmetrical bisacridine developed in our group) and the glutathione S-transferase/glutathione (GST/GSH) system. Here, we analyzed the concentration- and pH-dependent GSH conjugation of C-2028 in rat liver microsomes and cytosol. We also applied three recombinant human GST isoenzymes, which altered expression was found in various tumors. The...