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Wyniki wyszukiwania dla: anti-lock braking
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Bioavailability of Tannins and Other Oligomeric Polyphenols: a Still to Be Studied Phenomenon
PublikacjaPurpose of Review Polyphenols are a group of plant secondary metabolites characterized with the presence ofmultiples of phenol structural units. Tannins are plant originated phenolic substances, which play an important role in plant defense system as well as have found applications in medicine, industry, and other fields of human activity. Despite these, the mechanisms of bioavailability of these substances are poorly studied and...
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Pomiar wartości opóźnienia hamowania dla sprawnego i niesprawnego układu hamulcowego
PublikacjaW artykule przedstawiono wyniki badań: sprawny układ hamulcowy i niesprawny układ hamulcowy. Pomiary opóźnienia hamowania przeprowadzono na suchej nawierzchni asfaltowej. Wykonano układ, który rozszczelnia przewód hamulcowy przy przednim prawym kole w czasie jazdy. Wykonano symulację wycieku płynu hamulcowego
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NO-BROADCASTING OF NON-SIGNALLING BOXES VIA OPERATIONS WHICH TRANSFORM LOCAL BOXES INTO LOCAL ONES
PublikacjaWe deal with families of probability distributions satisfying non-signalling condition, called non-signalling boxes and consider a class of operations that transform local boxes into local ones (the one that admit LHV model). We prove that any operation from this class cannot broadcast a bipartite non-local box with 2 binary inputs and outputs. We consider a function called anti-Robustness which can not decrease under these operations....
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Pollutants in Airport Runoff Waters
PublikacjaRunoff waters from airport areas constitute a serious environmentalproblem. It is essential to monitor levels of pollutants emitted intothe environment and measure their toxicity on a continuous basis.The authors' aim was to critically review data on pollution fromaviation fuel combustion, aviation fuel spillage, the washing andcleaning of aircraft and airport service equipment, and the useof de-/anti-icing agents published in...
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Modification of quaternary structure of Candida albicans GlcN-6-P synthase and its desensitization to inhibition by UDP-GlcNAc by site-directed mutagenesis
PublikacjaSite-directed mutagenesis of the CaGFA1 gene encoding glucosamine-6-phosphate synthase from Candida albicans was performed. Desensitization of the enzyme to inhibition by UDPGlcNAc was achieved upon T487I and H492F substitutions at the UDP-GlcNAc binding site, exchange of D524, S525 and S527 for Ala at the dimer:dimer interface and construction of the tail-lock array (L434R and L460A) at the C-tail region. The first two sets if...
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X-Ray Diffraction, Mössbauer Spectroscopy and Magnetoelectric Effect Studies of Multiferroic Bi5Ti3FeO15 Ceramics
PublikacjaBi5Ti3FeO15 ceramics belongs to multiferroic class of materials. In this work it was prepared by solid-state sintering method and investigated by X-ray diffraction, Mössbauer spectroscopy, and magnetoelectric effect measurements. As it was proved by X-ray diffraction studies the single-phase Bi5Ti3FeO15 compound was obtained. The Mössbauer investigations revealed paramagnetic character of the compound at room temperature as well...
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Molecular Umbrella as A Nanocarrier for Antifungals
PublikacjaA molecular umbrella composed of two O‐sulfated cholic acid residues was applied for the construction of conjugates with cispentacin, containing a “trimethyl lock” (TML) or o‐dithiobenzylcarbamoyl moiety as a cleavable linker. Three out of five conjugates demonstrated antifungal in vitro activity against C. albicans and C. glabrata but not against C. krusei, with MIC90 values in the 0.22–0.99 mM range and were not hemolytic. Antifungal...
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Molecular modeling and evaluation of novel dibenzopyrrole derivatives as telomerase inhibitors and potential drug for cancer therapy
PublikacjaDuring previous years, many studies on synthesis, as well as on anti-tumor, anti-inflammatory and anti-bacterial activities of the pyrazole derivatives have been described. Certain pyrazole derivatives exhibit important pharmacological activities and have proved to be useful template in drug research. Considering importance of pyrazole template, in current work the series of novel inhibitors were designed by replacing central...
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Modelowanie reorganizacji ruchu w transporcie szynowym zwiększające efektywne wykorzystanie energii z hamowania odzyskowego
PublikacjaWe wstępie artykułu przedstawiono metody wykorzystania energii elektrycznej odzyskanej w procesie hamowania elektrodynamicznego. Szczególną uwagę zwrócono na metodę zwrotu odzyskanej energii do sieci jezdnej i wykorzystania jej przez inne pojazdy szynowe, której efektywne zastosowanie niejednokrotnie wymaga reorganizacji ruchu. W pracy przeanalizowano opisany w literaturze model organizacji ruchu w transporcie szynowym, który uwzględnia...
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The protective properties of graphene oxide coatings functionalized with phosphorus atoms.
PublikacjaRecently, electrophoretically deposited graphene oxide coatings are commonly applied as an anti-corrosion layer. However, improper adjustment of electrophoretic deposition (EPD) parameters as well as the hydrophilic nature of graphene oxide contribute to the formation of defects in the coatings and the increase in the wetting properties, respectively, and thus lead to a reduction of protective properties. The growth of wetting...
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Optymalizacja rozkładu jazdy na kolei z uwzględnieniem efektywności hamowania odzyskowego.
PublikacjaNa wstępie artykułu przybliżono czytelnikowi, czym jest rozkład jazdy na sieci kolejowej, na czym polega jego optymalizacja oraz odwołano się do literatury opisującej proces jego konstrukcji. W dalszej części przedstawiono kryteria optymalizacji rozkładu jazdy i zaproponowano podejście od strony efektywności wykorzystania energii pochodzącej z hamowania rekuperacyjnego, realizowanego metodą odzysku bezpośrednio do sieci trakcyjnej....
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Energy recovery effectiveness in trolleybus transport
PublikacjaNowadays the issue of electric energy saving in public transport is becoming a key area of interest whichis connected both with a growth in environmental awareness of the society and an increase in the pricesof fuel and electricity. One of the possibilities to reduce energy consumption in urban public transport isto increase the extent of regenerative braking energy utilization. This can be achieved by its accumulationin the supercapacitors...
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THE COST ANALYSIS OF CORROSION PROTECTION SOLUTIONS FOR STEEL COMPONENTS IN TERMS OF THE OBJECT LIFE CYCLE COST
PublikacjaSteel materials, due to their numerous advantages - high availability, easiness of processing and possibility of almost any shaping are commonly applied in construction for carrying out basic carrier systems and auxiliary structures. However, the major disadvantage of this material is its high corrosion susceptibility, which depends strictly on the local conditions of the facility and the applied type of corrosion protection system....
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The electrochemical impedance spectroscopy studies of cataphoretic-grown epoxy-based coatings
Dane BadawczeThe dataset contains electrochemical impedance spectroscopy spectra collected for epoxy-based cataphoretic coatings in order to determine the offered anti-corrosion protection. Particular spectra pertain to the coatings applied for the different magnitude of polarization potential imposed, namely 10V, 20V and 30V. The results were obtained within the...
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Synthesis of disubstituted 1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids derivatives
Publikacja1,3,4,9-tetrahydropyrano[3,4-b ]indole-1-acetic acid derivatives are of interest for pharmaceutical research as a core structure for synthesis of biological active substance - Etodolac (selective Cyclooxygenase-2 inhibitor, which belongs to the Non-steroidal Anti-inflammatory Drug, NSAID, that shows a clin-ically effective analgesic and anti-inflammatory activity). Here the way of synthesis of two 1,3,4,9-tetrahydropyrano[3,4-b...
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Carnivorous plants used for green synthesis of silver nanoparticles with broad-spectrum antimicrobial activity
PublikacjaIn this study, we exploit the anti-oxidative potential of four carnivorous plants to produce uniform and biologically active silver nanoparticles. The use of polyvinylpyrrolidone promoted syn-thesis of quasi-spherical nanoparticles characterized by stability and high uniformity. Their activity was tested against three human pathogens and three species of plant pathogenic bacteria. The study demonstrates the influence of synthesis...
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The Empirical Application of Automotive 3D Radar Sensor for Target Detection for an Autonomous Surface Vehicle’s Navigation
PublikacjaAvoiding collisions with other objects is one of the most basic safety tasks undertaken in the operation of floating vehicles. Addressing this challenge is essential, especially during unmanned vehicle navigation processes in autonomous missions. This paper provides an empirical analysis of the surface target detection possibilities in a water environment, which can be used for the future development of tracking and anti-collision...
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Flow cytometry analysis of DNA DSBs in telomerase positive and negative cell lines after treatment with TXT2 and TXT4
Dane BadawczeFlow cytometry analysis of DNA DSBs in telomerase positive (A549, H460) and negative (NHBE2594, U2OS) cell lines after treatment with equitoxic concentrations of TXT2 and TXT4. MTX and DMSO were used as positive and negative controls, respectively.
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Reduction of Tire Rolling Resistance by Optimization of Road Surfaces and Tires
PublikacjaDuring interaction between tire and road surface three very important phenomena are always in effect. One of them (very desirable) is friction that is important for traction, braking and cornering. Two other phenomena are not desirable at all, that is rolling resistance and noise. This paper discusses relations between road surface and tire parameters versus tire rolling resistance. Road surface texture, porosity, impedance, strength...
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Optimization of Energetic Train Cooperation
PublikacjaIn the article, possible ways of using energy recovered during regenerative braking of trains are presented. It is pointed out that the return of recovered electricity directly to the catenary and its use in the energy cooperation of vehicles can be a no-cost method (without additional infrastructure). The method of energy cooperation between trains and its main assumptions, that uses the law of conservation of energy, are described...
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Preclinical toxicological examination of a putative prostate cancer-specific 4-methyl-1-nitroacridine derivative in rodents
PublikacjaW pracy przedstawiono wyniki przedklinicznych badań toksykologicznych zwiazków C-1748 i C-857 na szczurach Copenhagen i myszach BALB/c, po podaniu dootrzewnowym lub dożylnym. U myszy dawki letalne (LD50) dla C-1748 wynosiły odpowiednio 9 i 13,4 mg/kg w porównaniu z 2,2 i 3 mg/kg dla C-857. U szczurów po podaniu dootrzewnowym lub dożylnym dla C-1748 dawki LD50 wynosiły odpowiednio 4 i 1,3 mg/kg. Nie stwierdzono zmian w liczbie komórek...
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Two novel nucleoside ester derivatives of chlorambucil as potential antileukemic prodrugs: a preliminary study
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Fatal iatrogenic vinorelbine poisoning
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Pedestrian on footbridges, vertical loads and response
PublikacjaThe paper is a synthesis of the experimental and theoretical investigations on dynamics of pedestrian bridges under vertical load The subject is divided into four issues.1) The pedestrian as a vertical dynamic load on footbridges, theoretic load function for walking and crouching.2) Crowd walking on the footbridge - pedestrian flow.3) Vertical lock-in effect.4) Response of the footbridge - numeric and side test results, -...
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Magnetoelectric effect in (BiFeO3)x–(BaTiO3)1-x solid solutions
PublikacjaThe aim of the present work was to study magnetoelectric effect (ME) in (BiFeO3)x–(BaTiO3)1x solid solutions in terms of technological conditions applied in the samples fabrication process. The rapidly growing interest in these materials is caused by their multiferroic behaviour, i.e. coexistence of both electric and magnetic ordering. It creates possibility for many innovative applications, e.g. in steering the magnetic memory...
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Long range molecular dynamics study of interactions of the eukaryotic glucosamine-6-phosphate synthase with fructose-6-phosphate and UDP-GlcNAc
PublikacjaGlucosamine-6-phosphate synthase (EC 2.6.1.16) is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. The final product of this pathway, uridine 5 diphospho Nacetyl- d-glucosamine (UDP-GlcNAc), is an essential substrate for assembly of bacterial and fungal cell walls. Moreover, the enzyme is involved in phenomenon of hexosamine induced insulin resistance in type II diabetes, which...
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The Physiological Effects of ASMR on Anxiety
PublikacjaPurpose: Autonomous Sensory Meridian Response is a novel phenomenon that is very popular these days on Youtube and Reddit to its anti-anxiety effects. As the name suggests, ASMR is a relaxing warm sensation that begins on the scalp and spreads throughout the body. This technique is also known as "brain massage," and it relies on soothing sights and sounds, like whispers and slow movements. Investigating these videos is primarily motivated...
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Applying of Doped Graphene Oxide Coatings for Corrosion Prevention
PublikacjaINTRODUCTION Graphene is a carbonaceous material characterized by extraordinary properties (high electron mobility, high surface area, high mechanical strength of 1100 GPa, very dense network hindering the passage of even the smallest helium atoms) [1]. Therefore, it found many applications, also as an anti-corrosive layer [2]. Electrophoretic Deposition (EPD) is one of the methods to deposit coatings. However, due to slight solubility...
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma-Recent Findings and Review
PublikacjaThe inflammatory process plays a significant role in the development of colon cancer (CRC). Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation but also impact carcinogenesis at all stages of the disease. Recent studies suggest that inflammation is of greater importance in the serrated pathway than in the adenoma-carcinoma pathway. Interleukins have gained the most attention due to their...
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Analiza i badania systemu antyspoofingowego GPS
PublikacjaArtykuł dotyczy problemu spoofingu w systemie GPS, polegającego na niepowołanej transmisji sygnałów imitujących sygnały odbierane z satelitów GPS. Takie działanie prowadzi do wyznaczenia przez odbiornik nawigacyjny nieprawidłowego położenia, prędkości i czasu. Zostały opisane metody przeciwdziałania spoofingowi, w szczególności poprzez przestrzenne przetwarzanie sygnałów. Przedstawiono wyniki badań symulacyjnych efektywności tych...
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Direct-Ultrasonic Assisted Microextraction Coupled with RTL-GC-FID/GC-MS as a Future Standard Procedure for Monitoring 26 potentially Allergenic Fragrances in Water Samples
PublikacjaThis research topic grew up as a result of awareness of constant anthropogenic and natural input to the environment constituents of personal care products (PCPs) residues. This group of emerging pollutants encompasses a wide range of chemicals, including potentially allergenic fragrance compounds. The aim of the present study was to investigate presence of 26 fragrance allergens in water samples. Simple and rapid methodology based...
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Synthesis, structural characterization and reactivity of new trisubstituted N1-acylamidrazones: solid state and solution studies
PublikacjaA series of new linear trisubstituted N1-acylamidrazones have been investigated using a variety of analytical techniques and theoretical calculations to check the influence of the type of N1-acyl substituent on the resonance forms and conformational behavior in the solid state and in solution. The 1D- and 2D-NMR experiments, supported by computational studies, revealed that in solution all amidrazones exhibit conformational syn/anti...
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Electrochemical determination of neurotransmitter serotonin using boron/nitrogen co-doped diamond-graphene nanowall-structured particles
PublikacjaElectrode fouling is a major issue in biological detection due to the adhesion of the protein itself and polymerization of biomolecules on the electrode surface, impeding the electron transfer ability and decreasing the current response. To overcome this issue, the use of anti-fouling material, especially boron-doped diamond (BDD) electrode, is an alternative way. However, the electrocatalytic activity of BDD is inadequate compared...
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Targeting Spike‐ACE2 Interface of SARS‐CoV‐2 and its Omicron Variant: A Comparative Screening of Potential Inhibitors for Existing and Anticipating Variants Using Molecular Modelling Approach
PublikacjaThe recent COVID pandemic has shown major impact on public health and economic crisis. Despite the development of many vaccines and drugs against the severe acute respiratory syndrome (SARS) coronavirus 2, the pandemic still persists. The continued spread of the virus is largely driven by the emergence of viral variants such as α, β, γ, delta, epsilon spike, omicron and its subvariants (BA.1,2,3) which can evade the current vaccines...
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The influence of external interference on AFM imaging, the use of a protective helmet
Dane BadawczeThis collection is of purely practical importance, showing how the presence of external disturbances can adversely affect the quality of imaging with an atomic force microscope. For this reason, it is also advisable to provide a link to a workshop-like study [1] as well as a huge number of commercial solutions available after entering the keyword "AFM...
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A Comprehensive Review of Phytonutrients as a Dietary Therapy for Obesity
PublikacjaObesity is a complex medical condition mainly caused by eating habits, genetics, lifestyle, and medicine. The present study deals with traditional diets like the Mediterranean diet, Nordic diet, African Heritage diet, Asian diet, and DASH, as these are considered to be sustainable diets for curing obesity. However, the bioavailability of phytonutrients consumed in the diet may vary, depending on several factors such as digestion...
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<i>N,N</i>'-diphenylthiourea acetone monosolvate
PublikacjaIn the title compound, C13H12N2S·C3H6O, the phenyl rings of the thiourea molecule are in syn and anti positions in relation to the C=S bond. Two molecules are connected by N-HS=C hydrogen bonds into a centrosymmetric dimer. An additional N-HO=C hydrogen bond to the acetone solvent molecule and some weak C-H interactions reinforce the crystal structure.
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Analysis of Drone Signals Based on Change Point Detection Algorithm
PublikacjaThe work presents an algorithm characterized by high precision and efficiency in identifying signals related to data transmission between the controller and the drone. Using an efficient change point detection algorithm and parallel analysis capabilities, this method facilitates rapid signal analysis. These features make the proposed algorithm a solid basis for developing an effective anti-drone defense system.
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Carbon dioxide potential reduction using Start-Stop system in a car
PublikacjaOperating fuel consumption increases significantly when the vehicle stops frequently while driving or when the engine is idling during braking. In such cases, the internal combustion engine consumes the fuel but the mechanical energy is not used by the drive system. The amount of fuel that is consumed in this time by the engine can potentially be saved if the car is equipped with a Stop-Start system. Start-Stop system automatically...
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Toxoplasma gondii Recombinant Antigens in the Serodiagnosis of Toxoplasmosis in Domestic and Farm Animals
PublikacjaToxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, and is a parasitic disease that occurs in all warm-blooded animals, including humans. Toxoplasmosis is one of the most common parasitic diseases of animals and results in reproductive losses. Toxoplasmosis in humans is usually caused by eating raw or undercooked meat or consuming dairy products containing the parasite. Diagnosis of toxoplasmosis is currently...
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Metal-Organic Framework (MOF)/Epoxy Coatings: A Review
PublikacjaEpoxy coatings are developing fast in order to meet the requirements of advanced materials and systems. Progress in nanomaterial science and technology has opened a new era of engineering for tailoring the bulk and surface properties of organic coatings, e.g., adhesion to the substrate, anti-corrosion, mechanical, flame-retardant, and self-healing characteristics. Metal-organic frameworks (MOFs), a subclass of coordinative polymers...
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Pomiarowa ocena efektywności systemu antyspoofingowego opartego na przetwarzaniu wieloantenowym
PublikacjaNiniejszy referat dotyczy problemu wykrywania i przeciwdziałania atakom typu spoofing w globalnych systemach nawigacji satelitarnej. Pierwsza część referatu stanowi wprowadzenie w temat spoofingu oraz przegląd sposobów jemu przeciwdziałania. Następnie, przedstawiono autorską koncepcję systemu antyspoofingowego opartego na przetwarzaniu wieloantenowym, a także opisano implementację prototypu tego systemu. Część trzecią poświęcono...
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Fuel cell noise data
Dane BadawczeMeasurement data of Hydrogen PEM fuel cels. The voltage fluctuations were measured over single cels of stack of 10 cels.
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SEM micrographs of the topography of Cu-Sn-TiO2 nanocomposite coatings
Dane BadawczeThe dataset contains the scanning electron microscopy (SEM) micrographs of nanocomposite Cu-Sn-TiO2 coatings electrodeposited from oxalic acid bath containing Cu and Sn salts as well as TiO2 nanoparticles under various treatments: mechanical stirring, ultrasonic or none. The details of the electrodeposition process are presented in the readme file attached...
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Some new soliton solutions to the higher dimensional Burger–Huxley and Shallow water waves equation with couple of integration architectonic
PublikacjaIn this paper, we retrieve some traveling wave, periodic solutions, bell shaped, rational, kink and anti-kink type and Jacobi elliptic functions of Burger’s equation and Shallow water wave equation with the aid of various integration schemes like improved -expansion scheme and Jacobi elliptic function method respectively. We also present our solutions graphically in various dimensions.
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Paulina Duch-Zebrowska MSc
Osoby15 lat zawodowego życia spędziłam w Londynie rozwijając się j ako manager procesów i nwestycyjnych. Projektowałam i prowadziłam budowę mieszkań w legendarnym Soho oraz sklepów na Oxford Street w Londynie. Mam dużą umiejętność nawiązywania kontaktów bazujących na wspólnym szacunku, na każdym poziomie i nwestycji, w tym z Inwestorem, Projektantami, jak również Wykonawcami. W tym roku wróciłam do Polski aby wykorzystać moje umiejętności...
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Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated /N-Tiophosphorylated Tacrine
PublikacjaNovel phosphorus and thiophosphorus tacrine derivatives were designed, synthesized and their biological activity and molecular modeling was investigated as a new potential anti-Alzheimer's disease (AD) agents. All new synthesized compound exhibited lower toxicity against neuroblastoma cell line (SH-SY5Y) in comparison with tacrine. Two analogues in the series, 7 and 9, demonstrated lack of cytotoxicity against hepatocellular cells...
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Creating a Remote Choir Performance Recording Based on an Ambisonic Approach
PublikacjaThe aim of this paper is three-fold. First, the basics of binaural and ambisonic techniques are briefly presented. Then, details related to audio-visual recordings of a remote performance of the Academic Choir of the Gdańsk University of Technology are shown. Due to the COVID-19 pandemic, artists had a choice, namely, to stay at home and not perform or stay at home and perform. In fact, staying at home brought in the possibility...
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The AFM micrographs and impedance study of epoxy coatings after exposure in corrosive media
Dane BadawczeThe dataset contains Atomic Force Microscopy (AFM) images and local impedance measurements of epoxy organic coating used as anti-corrosion protection, before and after 2-month exposure to sodium chloride solution. Additionally, there two local impedance spectra recorded after the coating exposure. The first one was recorded on intact coating surface,...
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PARP inhibition potentiates the cytotoxic activity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancer cells
PublikacjaTwo cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor genes are essential for DNA integrity and the maintenance of genomic stability.Approximately 5-10% of breast and ovarian cancers result from inherited alterations or mutations in these genes.Remarkably, BRCA1/BRCA2-deficient cells are hypersensitive to selective inhibition of poly(ADPribose) polymerase 1 (PARP-1),...