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Synthesis and biological evaluation of thiophosphate tricyclic coumarin derivatives as steroid sulfatase inhibitors
PublikacjaSteroid sulfatase (STS) enzyme inhibition is an important approach to the management of hormone-dependent breast cancer. In this paper, we report convenient methods for the synthesis and biological evaluation of thiophosphate tricyclic coumarin analogs exhibiting STS activity. The described methods are based on the straightforward preparation of 7-hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-2-one, 3-hydroxy- 7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one,...
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Mariusz Szkoda dr inż.
OsobyMariusz Szkoda urodził się w 1990 roku w Pieniężnie (woj. Warmińsko-Mazurskie), a II LO im. Feliksa Nowowiejskiego ukończył w Braniewie. Studia odbył w latach 2009–2014 na Wydziale Chemicznym Politechniki Gdańskiej (kierunek: Technologie ochrony środowiska, Złota Odznaka Absolwenta). Poza statusem doktoranta, mgr inż. Mariusz Szkoda od października 2017 r. jest także asystentem na Wydziale Chemicznym, a od 2014 roku współpracuje...
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Individual investors willingnes to invest in ESG in Poland survey results
Dane BadawczeThis dataset encompasses Polish citizens, including those being retail investors, attitude toward climate change and ESG investment. Dataset of two waves of the omnibus survey which provides representative database for Poland for February 2021. A specialized polling institute, was subcontracted to conduct the survey using Computer-Assisted Web Interviewing...
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High resolution XPS analysis of BDD electrode functionalization steps towards SARS-CoV-2 detection
Dane BadawczeThis dataset contains the results of the high-resolution XPS analyses of a set of boron-doped diamond (BDD) electrodes after consecutive functionalization steps toward anchoring of a receptor capable of SARS-CoV-2 virus detection. The analysis was carried out in the binding energy range of C1s, N1s, O1s, Ni2p3/2. The measurements were carried out on...
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Małgorzata Śmiałek-Telega dr hab. inż.
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Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies
PublikacjaA series of novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(6-substituted-4-chloro-1,3,5-triazin-2-ylamino)guanidine derivatives 9–20 have been synthesized by substitution of chlorine atom at the 1,3,5-triazine ring in compounds 5–8 with 3- or 4-aminobenzenesulfonamide and 4-(aminomethyl)benzenesulfonamide hydrochloride. All the synthesized compounds were evaluated for their inhibitory activity toward hCA I, II,...
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Szacowanie niepewności funkcji przetwarzania przetwornika LEM CT -5T metodą Monte Carlo
PublikacjaW referacie zaprezentowano metodologię szacowania niepewności funkcji przetwarzania przetwornika prądowego, na przykładzie przetwornika LEM CT-5T, przy zastosowaniu metody opartej na Przewodniku GUM, z zastosowaniem prawa propagacji niepewności oraz metody numerycznej Monte Carlo. Przedstawiono szczegółową analizę doboru rozkładu wielkości wejściowej. W przypadku metody Monte Carlo dobór rozkładu wielkości wejściowych jest bardzo...
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Szacowanie niepewności funkcji przetwarzania przetwornika LEM CT -5T metodą Monte Carlo
PublikacjaW referacie zaprezentowano metodologię szacowania niepewności funkcji przetwarzania przetwornika prądowego, na przykładzie przetwornika LEM CT-5T, przy zastosowaniu metody opartej na Przewodniku GUM z zastosowaniem prawa propagacji niepewności oraz metody numerycznej Monte Carlo. Przedstawiono szczegółową analizę doboru rozkładu wielkości wejściowej. W przypadku metody Monte Carlo dobór rozkładu wielkości wejściowych jest bardzo...
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Analiza możliwości wzrostu udziału transportu zbiorowego w wojewódzkich przewozach pasażerskich na przykładzie województwa pomorskiego
PublikacjaPodział zadań przewozowych pomiędzy dostępne środki transportu jest jednym z kluczowych wyzwań przy opracowaniu Planów Transportowych w regionach. Stan aktualny i prognozy prowadzone na obszarze Unii Europejskiej wskazują, że w najbliższych latach dominującym środkiem transportu pasażerskiego będzie samochód osobowy z zarysowującą się tendencją wzrostową. Dlatego bardzo istotnym działaniem przy budowie zintegrowanego systemu transportu...
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Concentrations of heavy metals and PCBs in the tissues of European beavers (Castor fiber) captured in northeastern Poland
PublikacjaEuropean beavers (Castor fiber) from two regions were examined to identify exposure to persistent environmental contaminants. A reference group was comprised of six animals from the Forest Division of Srokowo, and an exposed group was comprised of five animals from the vicinity of a former military airport operated in 1918–1986—both from Warmia land in Poland. 137 Cs in beavers' muscles was considered negligible for the overall...
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Jolanta Kowal dr hab.
OsobyJolanta Kowal has a Post-doctoral Degree in Social Sciences (dr hab., DSc) in the field of economics and finance, an assistant professor, researcher, and lecturer in the Institute of Psychology of Wroclaw University, and a professor of the Gdańsk University of Technology, Poland, a Jungian analyst. Jolanta from 2014 held functions in the Board of the Polish Chapter of the Association for Information Systems (PLAIS) (President 2015-2018,...
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Wojciech Litwin dr hab. inż.
Osoby1992÷1996 – Studia na Wydziale Mechanicznym Politechniki Gdańskiej1996 – Zatrudniony na Wydziale Oceanotechniki i Okrętownictwa PG2004 – Obrona pracy doktorskiej2014 – obrona rozprawy habilitacyjnej2012 – obejmuje funkcję prodziekan ds. Nauki na Wydziale Oceanotechniki i OkrętownictwaUczestniczył w wielu projektach badawczych oraz pracach zleconych przez przemysł związanych z łożyskowaniem ślizgowym wałów głównych oraz niekonwencjonalnymi...
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[AEiE, ITiT] Scientific methods of computer data analysis and presentation - 2022/2023
Kursy Online{mlang pl} Dyscyplina: AEiE, ITiT Zajęcia obowiązkowe dla doktorantów II roku Prowadzący: Tomasz Berezowski Liczba godzin: 30 Forma zajęć: wykład/projekt/seminarium {mlang} {mlang en} Discipline: AEiE, ITiT Obligatory course for 2nd-year PhD students Academic teacher: Tomasz Berezowski Total hours of training: 30 teaching hours Course type: Lecture/project/seminar {mlang}
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[AEEiTK, ITiT] Scientific methods of computer data analysis and presentation - 2023/2024
Kursy Online{mlang pl} Dyscyplina: AEiE, ITiT Zajęcia obowiązkowe dla doktorantów II roku Prowadzący: Tomasz Berezowski Liczba godzin: 30 Forma zajęć: wykład/projekt/seminarium {mlang} {mlang en} Discipline: AEiE, ITiT Obligatory course for 2nd-year PhD students Academic teacher: Tomasz Berezowski Total hours of training: 30 teaching hours Course type: Lecture/project/seminar {mlang}
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Scientific methods of computer data analysis and presentation
Kursy Online -
Międzynarodowa konferencja NANOSMAT
WydarzeniaKonferencja NANOSMAT jest poświęcona inżynierii materiałowej (Nanoscience, Engineering and Nanotechnology and Beyond NANO); www.nanosmat-conference.com
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Wireless Charging Station Design for Electric Scooters: Case Study Analysis
PublikacjaThis study proposes an example of a wireless charging station design for a small-scale vehicle available on the market. The article analyzes basic transmitter inverter topologies and their compensation methods in terms of flexibility of control, tolerance to uncertainty in positioning, and the possibility of decreasing the integration price. Our comprehensive analysis focuses on the battery voltage range, energy capacity, cost,...
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Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5- methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII
PublikacjaA series of novel N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines 9 e41 have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA.EC 4.2.1.1), that is the cytosolic CA I and II, and cancer-associated isozymes CA IX and XII. Against the human CA I investigated compounds showed KI in the range of 87e6506 nM, toward hCA II ranging from 7.8 to 4500 nM,...
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Efficient Multi-Fidelity Design Optimization of Microwave Filters Using Adjoint Sensitivity
PublikacjaA simple and robust algorithm for computationally efficient design optimiza-tion of microwave filters is presented. Our approach exploits a trust-region (TR)-based algorithm that utilizes linear approximation of the filter response obtained using adjoint sensitivity. The algorithm is sequentially executed on a family of electromagnetic (EM)-simulated models of different fidelities, starting from a coarse-discretization one, and...
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Upgrading low value-added activities in global value chains: a functional specialisation approach
PublikacjaThis paper aims to identify patterns of functional specialisation (FS) in global value chains (GVCs) and determinants of upgrading them for selected Central Eastern European (CEE) economies. By combing the World Input-Output Database with data on occupations, we reveal a new FS pattern among subgroups of CEEs. Poland and Slovakia have an unfavourable GVC position and specialise in low value-added fabrication function. In contrast,...
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The new investing effectiveness evaluation multi-criteria method in modern supply systems
PublikacjaThe important problem in the processes of modelling and programming the development of sustainable energy sector is the multi-criteria manner of assessing the effectiveness of investments. The goal of this paper is to show how to take into account the impact of investments in multidimensional modelling decision-making processes. This goal can be achieved through the development, presentation, and use of a new multi-criteria method...
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Arterial cannula shape optimization by means of the rotational firefly algorithm
PublikacjaThe article presents global optimization results of arterial cannula shapes by means of the newly modified firefly algorithm. The search for the optimal arterial cannula shape is necessary in order to minimize losses and prepare the flow that leaves the circulatory support system of a ventricle (i.e. blood pump) before it reaches the heart. A modification of the standard firefly algorithm, the so-called rotational firefly algorithm,...
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Multi-Fidelity Local Surrogate Model for Computationally Efficient Microwave Component Design Optimization
PublikacjaIn order to minimize the number of evaluations of high-fidelity (“fine”) model in the optimization process, to increase the optimization speed, and to improve optimal solution accuracy, a robust and computational-efficient multi-fidelity local surrogate-model optimization method is proposed. Based on the principle of response surface approximation, the proposed method exploits the multi-fidelity coarse models and polynomial interpolation...
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Verification of GNSS Measurements of the Railway Track Using Standard Techniques for Determining Coordinates
PublikacjaThe problem of the reproduction of the railway geometric layout in the global spatial system is currently solved in the form of measurements that use geodetic railway networks and also, in recent years, efficient methods of mobile positioning (mainly satellite and inert). The team of authors from the Gdańsk University of Technology and the Maritime University in Gdynia as part of the research project InnoSatTrack is looking for...
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Zespół wypalenia zawodowego i zmęczenie w kontekście pracy zmianowej i stresu zawodowego wśród pielęgniarek chirurgicznych
PublikacjaTwo aspects of work-related consequences among surgery nurses are discussed: burnout syndrome and fatigue, having an impact on the quality of medical care and safety of patients. Siegrist's effort-reward imbalance model has been adopted as a concept of occupational stress. The organization of working time, i.e. the length of shifts and their rotation, was considered. Nurses on twelve-hour shifts worked much harder, were more tired...
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Józef Pacyna prof. dr hab. inż.
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Wpływ postrzeganego ryzyka oraz czynników wizerunkowych na zamiar zakupu marek własnych sieci handlowych
PublikacjaCelem przeprowadzonych badań była analiza wpływu wizerunku sklepu, postrzeganego ryzyka oraz wizerunku cenowego marek własnych na zamiar ich zakupu. Dokonano replikacji modelu zaproponowanego przez M.F. Diallo i w jej ramach zastosowano technikę wywiadu realizowanego za pośrednictwem Internetu (CAWI) i przeprowadzono analizy z wykorzystaniem modelu równań strukturalnych (SEM) przy pomocy oprogramowania AMOS. Stwierdzono, że zamiar...
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Simple synthesis route for fabrication of protective photo‐crosslinked poly(zwitterionic) membranes for application in non‐enzymatic glucose sensing
PublikacjaThis work focuses on the fabrication of non-enzymatic glucose sensing materials based on laser-formed Au nanoparticles embedded in Ti-textured substrates. Those materials possess good catalytic activity toward glucose oxidation in 0.1 × phosphate buffered saline as well as resistance to some interferants, such as ascorbic acid, urea, and glycine. The electrodes are further coated with three different polymers, that is, Nafion,...
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Adapting Agile Practices to Security Context – Practitioners’ Perspective
PublikacjaIn this paper we explore the problem of introducing agile practices to projects dealing with systems with high security requirements. We also propose an approach based on AgileSafe method and OWASP ASVS guidelines, that could support such introduction. What is more, we present the results of two surveys aimed at analyzing IT practitioners’ views on applying agile methods to security reliant systems as well as evaluating the set...
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Natalia Sokół dr inż.
OsobyBACKGROUND Master of Science in Light and Lighting (2008-2009/11) The UCL Bartlett School of Graduate Studies, Faculty of the Built Environment, London, UK, www.bartlett.ucl.ac.uk MA Degree in Interior Architecture (1999-2004), The Academy of Fine Arts, Poznan, Poland, www.uap.edu.pl MA Degree in Art Education (1997-2002), Academy of Fine Arts, Poznan, Poland, www.uap.edu.pl MAIN RESEARCH AREAS · ...
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Automatyczna weryfikacja klienta bankowego w oparciu o multimodalne technologie biometryczne
PublikacjaW referacie przedstawiono przegląd rozwiązań wykorzystywanych w bankach do weryfikacji tożsamości klientów. Ponadto zawarto opis metod biometrycznych aktualnie wykorzystywanych w placówkach bankowych wraz z odniesieniem do skuteczności i wygody korzystania z dostępnych rozwiązań. Zaproponowano rozszerzenie zakresu wykorzystania technologii biometrycznych, wskazując kierunek rozwoju systemów bezpieczeństwa dla poprawy dostępu do...
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Exploring the factor structure and the validity of the abbreviated Basic and Earning Self-Esteem Scales
PublikacjaThe original longer versions (Forsman & Johnson, 1996) and abbreviated versions of the Basic and Earning Self-Esteem Scales have been used in clinical and non-clinical settings, but little is known about the factor structure and the validity of these scales in their abbreviated forms. The original longer versions of the scales comprise several dimensions, but both abbreviated versions of the scales have been interpreted as if they...
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Employment Specialization in the Enlarged European Union
PublikacjaThis paper presents the evolution of absolute employment specialization along the course of economic growth of 25 EU countries. We focus on the degree to which EU economies concentrate labor force in a few sectors/industries. Using disaggregated statistics classified according to NACE Rev. 1 division (71 sectors) we calculate various synthetic indices measuring the degree of diversification typical for the employment structures...
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Contemporary multifunctional buildings towards a sustainable development of the housing environment
PublikacjaDevelopment of contemporary urban centers depends on the basis that buildings present more and more complex structures in terms of size and purpose. They are referred to as multifunctional buildings. This aspiration has its origins in the development of urban centers and in the desire to optimize the built-up areas. The article presents the theory of the approach to the design of multifunctional buildings with a focus on the residential...
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Zero-pole approach to computer aided design of in-line siw filters with transmission zeros
PublikacjaThis paper presents a design of a new type of in-line pseudo-elliptic filters implemented in substrate integrated waveguide(SIW) technology. To realize transmission zeros in in-line topology,frequency-dependent couplings were used. Such dispersive couplingswere implemented as shorted stubs. The design process startswith the generation of a suitable starting point. To this end, anapproximation of SIW as a rectangular waveguide is...
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Neural Network-Based Sequential Global Sensitivity Analysis Algorithm
PublikacjaPerforming global sensitivity analysis (GSA) can be challenging due to the combined effect of the high computational cost, but it is also essential for engineering decision making. To reduce this cost, surrogate modeling such as neural networks (NNs) are used to replace the expensive simulation model in the GSA process, which introduces the additional challenge of finding the minimum number of training data samples required to...
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Active Kriging-based conjugate first-order reliability method for highly efficient structural reliability analysis using resample strategy
PublikacjaEfficient structural reliability analysis method is crucial to solving reliability analysis of complex structural problems. High-computational cost and low-failure probability problems greatly limit the efficiency in structural reliability analysis problems, causing the safety and reliability of the structure to be questioned. In this work, a highly efficient structural reliability analysis method coupling active Kriging algorithm...
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An isogeometric finite element formulation for boundary and shell viscoelasticity based on a multiplicative surface deformation split
PublikacjaThis work presents a numerical formulation to model isotropic viscoelastic material behavior for membranes and thin shells. The surface and the shell theory are formulated within a curvilinear coordinate system,which allows the representation of general surfaces and deformations. The kinematics follow from Kirchhoff–Love theory and the discretization makes use of isogeometric shape functions. A multiplicative split of the surface...
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Rapid Surrogate-Aided Multi-Criterial Optimization of Compact Microwave Passives Employing Machine Learning and ANNs
PublikacjaThis article introduces an innovative method for achieving low-cost and reliable multi-objective optimization (MO) of microwave passive circuits. The technique capitalizes on the attributes of surrogate models, specifically artificial neural networks (ANNs), and multi-resolution electromagnetic (EM) analysis. We integrate the search process into a machine learning (ML) framework, where each iteration produces multiple infill points...
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Numerical and quantitative analysis of HIV/AIDS model with modified Atangana-Baleanu in Caputo sense derivative
PublikacjaFractional calculus plays an important role in the development of control strategies, the study of the dynamical transmission of diseases, and some other real-life problems nowadays. The time-fractional HIV/AIDS model is examined using a novel method in this paper. Based on the Atangana-concept Baleanu’s of a derivative in the Caputo sense, the current modified fractional derivative operator uses singular and non-local kernels....
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Economic growth, structural change and quality upgrading in New Member States
PublikacjaThe purpose of this research is to present the recent developments concerning structural change and productivity growth in New Member States and the role played in such process by country specific factors. We focus on ten countries (NMS-10) which joined the EU in 2004 and analyze productivity dynamics of their labor structures between the years 1995 and 2005 in a comparative setting versus EU-15 economies. NMS-10 have gone through...
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On weak solutions of the boundary value problem within linear dilatational strain gradient elasticity for polyhedral Lipschitz domains
PublikacjaWe provide the proof of an existence and uniqueness theorem for weak solutions of the equilibrium problem in linear dilatational strain gradient elasticity for bodies occupying, in the reference configuration, Lipschitz domains with edges. The considered elastic model belongs to the class of so-called incomplete strain gradient continua whose potential energy density depends quadratically on linear strains and on the gradient of...
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Chromium-Catalyzed CO2–Epoxide Copolymerization
PublikacjaIminopyrrole, aminopyrrole, and aminophosphine ligands were complexed with various chromium sources, producing eight complexes that were tested for their catalytic behavior toward epoxide–CO2 copolymerization. As elucidated by MALDI-TOF-MS, copolymerizations afforded polycarbonates and poly(ether-carbonates) exhibiting linear or cyclic topologies.
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Editorial: Knowledge management and ontologies. Part 2
PublikacjaPrzedstawiono najnowsze kierunki badań w zakresie obszaru zarządzania wiedzą i ontologicznej reprezentacji wiedzy.
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Editorial: Knowledge management and ontologies. Part 1
PublikacjaPrzedstawiono najnowsze kierunki badań w zakresie obszaru zarządzania wiedzą i ontologicznej reprezentacji wiedzy.
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Technologia ''Wiki'' jako mechanizm budowania społeczeństwa i organizacji opartych na wiedzy
PublikacjaOmówiono podstawowe przesłanki budowania społeczeństwa opartego na wiedzy. Zaproponowano technologię WIKI jako mechanizm modelowania w tym budowaniu.
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Information and Konowledge management: advances, approaches, challenges and critical issues
PublikacjaPrzedstawiono zarys najnowszych osiągnięć w zakresie zarządzania wiedza i informacja wraz z ich krytyczna ocena.
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Creating the e-decisional community through the knowledge supply chan system
PublikacjaW pracy przedstawiono zasady tworzenia społeczeństwa cyfrowego opartego na wymianie wiedzy dostępnej w nośnikach internetowych. Omówiono zasady modelowania takiej wiedzy i budowy tzw. łańcucha zaopatrzenia w wiedzę.
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Hard and Soft Modeling Tools and Approaches to Data and Information Management in Real-Life Projects and Systems : special issue editorial
PublikacjaOmówiono miękkie oraz twarde narzędzia służące do modelowania i symulacji przepływów dużych ilości danych oraz informacji. Przedstawiono mozliwości zastosowania tego typu narzędzi w funkcjonowaniu systemów rzeczywistych.
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Buliding organizational knowledge in software and systems R&D organization
PublikacjaOmówiono specyficzne dla firm software podejście do tworzenia wiedzy organizacyjnej. Zaproponowano narzędzia pomocne w tworzeniu takiej wiedzy.