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Wyniki wyszukiwania dla: ibuprofen and its metabolites
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Discrete element method simulations of fracture in concrete under uniaxial compression based on its real internal structure
PublikacjaThe paper describes experimental and numerical results of concrete fracture under quasi-static uniaxial compression. Experimental uniaxial compression tests were performed on concrete cubic specimens. Fracture in concrete was detected at the aggregate level by means of three non-destructive methods: three-dimensional X-ray microcomputed tomography, two-dimensional scanning electron microscope and manual two-dimensional digital...
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Glutathione conjugation of the antitumor-active 1-nitroacridine derivatives compounds C-857 and C-1748 – the major role of glutathione S-transferase M1-1
Dane BadawczeObjectives: C-857 and C-1748 are antitumor-active agents, monomers of unsymmetrical bisacridine derivatives. The aim of this study was to analyze their glutathione (GSH) conjugation in vitro in the presence of glutathione S-transferase (GST) M1-1.
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Phytochemical screening and biological evaluation of Greek sage (Salvia fruticosa Mill.) extracts
PublikacjaThis study explores the influence of extraction solvents on the composition and bioactivity of Salvia fruticosa extracts. Ultrasound-assisted extraction with water, ethanol and their mixtures in variable proportions was used to produce four different extracts. An untargeted UPLC/MS‑based metabolomics was performed to discover metabolites profile variation between the extracts. In the analyzed samples, 2704 features had been detected,...
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International Conference on Worldwide Computing and Its Applications
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International Symposium on Information Theory and Its Applications
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Zasada ubi ius, ibi remedium
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RTS Noise in Optoelectronic Coupled Devices
PublikacjaPrzedstawiono wyniki pomiarów szumów z zakresu małuch częstotliwości transoptorów typu CNY17. Pomiary wykonano w systemie zaprojektowanym i skonstruowanym przez Autorów. Stwierdzono występowanie szumów RTS w kilku egzemplarzach badanej próby transoptorów. Przeprowadzono analizę szumów RTS, zarówno w dziedzinie czasu, jak i w dziedzinie częstotliwości. Oszacowano wartość częstotliwości, przy której występują szumy wybuchowe, na...
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The impact of ICTs on women’s economic empowerment
PublikacjaIt is widely argued that ICTs enable the inclusion of low-skilled and traditionally marginalized groups, such as women, people with disabilities, and workers at the base of the pyramid (BoP), in the labor market. In this paper, we investigate the determinants of female participation in the labor market in developing countries with a focus on the impact of the use of ICTs on female labor force participation. We conduct a panel study...
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TRAFFIC MODEL OF A MULTIDOMAIN IMS/NGN
PublikacjaIn this paper we continue our research and present an analytical traffic model of a multidomain Next Generation Network (NGN), which is standardized for delivering multimedia services based on the IP Multimedia Subsystem (IMS). The model takes into account several service scenarios (including registration, intra- and inter-operator calls) and a large set of network parameters. Using the model mean Call Set-up Delay and mean Call...
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Identification of Optocoupler Devices with RTS Noise
PublikacjaThe results of noise measurements in low frequency range for CNY 17 type optocouplers are presented. The research were carried out on devices with different values of Current Transfer Ratio (CTR). The methods for identification of Random Telegraph Signal (RTS) in noise signal of optocouplers were proposed. It was found that the Noise Scattering Pattern method (NSP method) enables to identify RTS noise as non-Gaussian component...
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A new methof for identyfication of RTS noise
PublikacjaIn the paper a new method, called the Noise Scattering Pattern (NSP) method, for RTS noise identyfication in a noise signal is presented. Examples of patterns of the NSP method are included.
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Error analysis for European IGS stations
PublikacjaEach of the GPS time series that describes the changes of topocentric components consists of a deterministic and a stochastic part, whose character influences the errors of the deterministic parameters. As to the uncertainties of reliable velocities of permanent satellite station systems, surveys that estimate and take into account any dependencies that may affect subsequent operational efficiency are very important. For this analysis,...
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The Impact of ICTs on Women’s Economic Empowerment
PublikacjaIt is widely argued that ICTs enable the inclusion of low-skilled and traditionally marginalized groups, such as women, people with disabilities, and workers at the base of the pyramid (BoP), in the labor market. In this paper, we investigate the determinants of female participation in the labor market in developing countries with a focus on the impact of the use of ICTs on female labor force participation. We conduct a panel study...
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Quality Parameters in IMS/NGN Networks
PublikacjaThe Next Generation Network (NGN) architecture, including elements of the IP Multimedia Subsystem (IMS) concept, is a proposition of a telecommunication network dedicated to the needs of current and future information society. The main goal of NGN is to provide Quality of Service (QoS), for which proper network design is necessary with respect to among others standardized call processing performance parameters, including expected...
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A simple graphene-based pipette tip solid-phase extraction of malondialdehyde from human plasma and its determination by spectrofluorometry
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Porphyrazine with bulky 2-(1-adamantyl)-5-phenylpyrrol-1-yl periphery tuning its spectral and electrochemical properties
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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
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Core/shell structured silica spheres with controllable thickness of mesoporous shell and its adsorption, drug storage and release properties
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The Use of Chlorophyll Fluorescence as an Indicator of Predicting Potato Yield, Its Dry Matter and Starch in the Conditions of Using Microbiological Preparations
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Assessing Food Insecurity and Its Drivers among Smallholder Farming Households in Rural Oyo State, Nigeria: The HFIAS Approach
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Expression of high affinity choline transporter during mouse development in vivo and its upregulation by NGF and BMP-4 in vitro
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Truncation of Huia versabilis Bowman-Birk inhibitor increases its selectivity, matriptase-1 inhibitory activity and proteolytic stability
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ATP4A autoimmunity in pediatric patients with type 1 diabetes and its relationship to blood count, iron metabolism, and vitamin B12
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Influence of Polymorphisms in DNA Repair GenesXPD, XRCC1andMGMTon DNA Damage Induced by Gamma Radiation and its Repair in LymphocytesIn Vitro
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Single-dopant organic white electrophosphorescent diodes with very high efficiency and its reduced current density roll-off
PublikacjaW pracy opisano konstrukcję wysokowydajnej diody elektrofosforescencyjnej zawierającej domieszkę organicznego kompleksu platyny PtL2Cl (L oznacza organiczny ligand). Dioda emituje światło białe które pochodzi od ekscymerów świecących w czerwieni i wzbudzonych monomerów świecących w części niebieskiej widma. Kwantowa wydajność świecenia diody wynosi ok. 15% i słabo maleje ze wzrostem gęstości płynącego prądu elektrycznego.
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Air pollution in the places of Betula pendula growth and development changes the physicochemical properties and the main allergen content of its pollen
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Application of INAA and ETAAS techniques for human samples analysis in evaluation of the impact of Gdansk Phosphatic Fertilizer Plant on its workers
PublikacjaW pracy przedstawiono wyniki badań wpływu Gdańskich Zakładów Nawozów Fosforowych na zdrowie pracowników. Oznaczano stężenia (techniką INAA) Al, As,Au, Br, Ca, Cl, Cu, Dy, I, In, K, La, Mg, Mn, Mo, Na, S, Sb, Sm, Ti, U, V,W, Zn we włosach, paznokciach i filtrach z pyłem zebranych od 21 pracowników fabryki oraz 5 osób z grupy kontrolnej nie związanej z zakładem. Ponadto oznaczono Cd, Cr, Cu, Fe, Mo, Ni i Zn w moczu przy użyciu...
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Wpływ starzenia stali budowlanej na jej właściwości mechaniczne. The effect of structural steel aging on its mechanical properties
PublikacjaPrzedstawiono wyniki badań właściwości mechanicznych i struktury trzech elementów stalowej konstrukcji budowlanej po długotrwałej eksploatacji.
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Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease
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Functional Similarities and Differences of an Archaeal Hsp70(DnaK) Stress Protein Compared with its Homologue from the Bacterium Escherichia coli
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RE-SHAPING THE LAND AND WATER CONNECTIONS AND ITS ROLE IN ACHIEVING LANDSCAPE AND ECOLOGICAL SYSTEMS’ CONTINUITY ON THE POST-INDUSTRIAL TERRITORIES
PublikacjaThis paper delves into recently applied strategies of creating new water areas and modifying the existing ones as a part of the transformation processes of post-industrial territories. It proves that while the pursuit for unique architectural and urban space values remains an important factor contributing to such modifications, they may also play an important role in reclaiming ecological systems continuity. On the basis of theoretical...
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Intramolecular transformation of an antifungal antibiotic nystatin A1 into its isomer, iso-nystatin A1 - structural and molecular modeling studies
PublikacjaNystatin A1, a polyene macrolide antifungal antibiotic, in a slightly basic or acidic solution undergoes an intramolecular transformation, yielding a structural isomer, the translactonization product, iso-nystatin A1 with lactone ring diminished by two carbon atoms. Structural evidence is provided by advanced NMR and Mass Spectrometry (MS) studies. Molecular dynamics simulations and quantum mechanics calculations gave the insight...
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Structure of solvation water around the active and inactive regions of a type III antifreeze protein and its mutants of lowered activity
PublikacjaWater molecules from the solvation shell of the ice-binding surface are considered important for the antifreeze proteins to perform their function properly. Herein, we discuss the problem whether the extent of changes of the mean properties of solvation water can be connected with the antifreeze activity of the protein. To this aim, the structure of solvation water of a type III antifreeze protein from Macrozoarces americanus (eel...
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The accessibility, necessity, and significance of certified reference materials for total selenium content and its species to improve food laboratories' performance
PublikacjaMicronutrients are one of the most important groups of nutrients that our body needs daily in trace amounts to tackle deficiencies. Selenium (Se) is a mineral that occurs naturally in foods and is an essential component of selenoproteins that support the healthy functioning of the human body. Therefore, monitoring dietary Se concentrations must be a higher priority to meet daily intakes. Fulfillment can be addressed through applying...
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Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives
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A 0.5-V bulk-driven voltage follower / DC level shifter and its application in class AB output stage
PublikacjaA simple realization of a 0.5-V bulk-driven voltage follower/DC level shifter, designed in a 0.18um CMOS technology is presented in the paper. The circuit is characterized by large input and output voltage swings, and a DC voltage gain close to unity. The DC voltage shift between input and output terminals can be regulated in a certain interval around zero, by means of biasing current sinks. An application of the proposed voltage...
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Identification of antigen Ag43 in uropathogenic Escherichia coli Dr+ strains and defining its role in the pathogenesis of urinary tract infections
PublikacjaUrinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most common bacterial infectious diseases in the developed world. The urovirulence of UPEC is mainly associated with the surface-exposed fimbrial adhesins and adhesins of the autotransporter (AT) family. The best studied of theses proteins is antigen 43 (Ag43) mediating cell aggregation, adhesion and biofilm development as the causes of...
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Analysis of Positioning Error and Its Impact on High Frequency Performance Parameters of Differential Signal Coupler of Differential Signal Coupler
PublikacjaThis paper presents the analysis of the effect of differential signal coupler positioning accuracy on its high frequency performance parameters for contact-less high speed chip-to-chip data transmission on PCB application. Our considerations are continuation of the previous works on differential signal coupler concept, design methodology and analysis for high speed data transmission monitoring presented in [1, 2]. The theoretical...
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5-Thiocyanato-2′-deoxyuridine as a possible radiosensitizer: electron-induced formation of uracil-C5-thiyl radical and its dimerization
PublikacjaIn this work, we have synthesized 5-thiocyanato-2′-deoxyuridine (SCNdU) along with the C6-deuterated nucleobase 5-thiocyanatouracil (6-D-SCNU) and studied their reactions with radiation-produced electrons. ESR spectra in γ-irradiated nitrogen-saturated frozen homogeneous solutions (7.5 M LiCl in H2O or D2O) of these compounds show that electron-induced S–CN bond cleavage occurs to form a thiyl radical (dU-5-S˙ or 6-D-U-5-S˙) and...
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Influence of several biodegradable components added to pure and nanosilver-doped PMMA bone cements on its biological and mechanical properties
PublikacjaAcrylic bone cements (BC) are wildly used in medicine. Despite favorable mechanical properties, processability and inject capability, BC lack bioactivity. To overcome this, we investigated the effects of selected biodegradable additives to create a partially-degradable BC and also we evaluated its combination with nanosilver (AgNp). We hypothesized that using above strategies it would be possible to obtain bioactive BC. The Cemex...
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How does climate change affect ice formation and presence in rivers, lakes and oceans, as well as its impact on infrastructure
PublikacjaIce season in rivers, lakes, seas and oceans is sensitive to climate change due to the high homologous temperature. Two vital aspects of the predicted climate change are increasing average air temperature and increasing variability in the weather. These cause delayed formation of ice, thinner ice and shorter duration of seasonal ice covers, the geographical ice margin to move further away from the equator, the perennial ice to...
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The Influence of a Photovoltaic Micro-Installation on the Low-Frequency Parameters of Electricity at PCC and Its Impact on the Thermal Characteristics of Selected Devices
PublikacjaThis manuscript illustrates the measurement results of parameters describing the quality of energy at the PCC (point of common coupling) of a photovoltaic micro-installation that can significantly affect devices in the same power grid. The analyses reflecting heating of selected devices used in domestic installations, which were performed in an isolated laboratory environment, are also indicated. The conducted study aimed at checking...
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Structural and Material Determinants Influencing the Behavior of Porous Ti and Its Alloys Made by Additive Manufacturing Techniques for Biomedical Applications
PublikacjaOne of the biggest challenges in tissue engineering is the manufacturing of porous structures that are customized in size and shape and that mimic natural bone structure. Additive manufacturing is known as a sufficient method to produce 3D porous structures used as bone substitutes in large segmental bone defects. The literature indicates that the mechanical and biological properties of scaffolds highly depend on geometrical features...
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The Influence of Loop Heat Pipe Evaporator Porous Structure Parameters and Charge on Its Effectiveness for Ethanol and Water as Working Fluids
PublikacjaAbstract: This paper presents the results of experiments carried out on a specially designed experimental rig designed for the study of capillary pressure generated in the Loop Heat Pipe (LHP) evaporator. The commercially available porous structure made of sintered stainless steel constitutes the wick. Three different geometries of the porous wicks were tested, featuring the pore radius of 1, 3 and 7 um. Ethanol and water as two...
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Electrochemical synthesis of 2D copper coordination-polymers: Layer-stacking deviation induced by the solvent and its effect on the adsorptive properties
PublikacjaA 2D Cu-based Metal-Organic Framework (MOF), namely copper-terephthalate (Cu(1,4-BDC)), was successfully synthesized by electrochemical method for effective methylene blue (MB) sorption from aqueous solutions. The composition, morphology, and the presence of functional groups in the obtained material were verified by Fourier Transform Infrared spectroscopy (FTIR), Powder X-Ray Diffraction (PXRD), Thermal (TGA), and Elemental (EA)...
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Reverse vaccinology-based prediction of a multi-epitope SARS-CoV-2 vaccine and its tailoring to new coronavirus variants
PublikacjaThe genome feature of SARS-CoV-2 leads the virus to mutate and creates new variants of concern. Tackling viral mutations is also an important challenge for the development of a new vaccine. Accordingly, in the present study, we undertook to identify B- and T-cell epitopes with immunogenic potential for eliciting responses to SARS-CoV-2, using computational approaches and its tailoring to coronavirus variants. A total of 47 novel...
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The optimization of enzyme immobilization at Au-Ti nanotextured platform and its impact onto the response towards glucose in neutral media
PublikacjaThe market of non-invasive glucose sensors is drastically growing due to increasing number of people suffering from diabetes. Therefore, there is a significant need for any improvement in the field of biosensors that can be used for monitoring glucose level in human body. In recent years the emphasis is put onto the modification of electrode material with enzymes possessing recognition centre specific towards particular molecules....
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Removal of Arsenic from Wastewater Using Hydrochar Prepared from Red Macroalgae: Investigating Its Adsorption Efficiency and Mechanism
PublikacjaArsenic (As) is a prominent carcinogen component produced via both geogenic and anthropogenic processes, posing serious risks to human health. This study aimed to investigate the potential of hydrochar prepared from red macroalgae for removing As from synthetic wastewater. The hydrochar was produced through 5 h hydrothermal carbonization (HTC) treatment at 200 °C, and then, chemically activated with ferric chloride hexahydrate...
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Chemical investigation on the mechanism and kinetics of the atmospheric degradation reaction of Trichlorofluoroethene by OH⋅ and Its subsequent fate in the presence of O2/NOx
PublikacjaThe M06-2X/6-311++G(d,p) level of theory was used to examine the degradation of Trichlorofluoroethene (TCFE) initiated by OH⋅ radicals. Additionally, the coupled-cluster single-double with triple perturbative [CCSD(T)] method was employed to refine the single-point energies using the complete basis set extrapolation approach. The results indicated that OH-addition is the dominant pathway. OH⋅ adds to both the C1 and C2 carbons,...
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Combustion characteristics and retention-emission of selenium during co-firing of torrefied biomass and its blends with high ash coal
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