Wyniki wyszukiwania dla: MINIGAP
-
The share of investments in gold and oil using the example of selected European stock exchanges– A comparative analysis
PublikacjaIn this article, optimal investment portfolios with minimal risk and maximum efficiency were calculated. The portfolios were designated for ten selected European stock exchanges, based on the listings of the twenty largest companies in each of those markets. All calculations were made based on company shares only, company shares and investments in gold, shares of companies and investments in crude oil as well as shares of companies...
-
Fatty acids as molecular carriers in cleavable antifungal conjugates
PublikacjaConjugates composed of C2-18 fatty acid (FA) residues as a molecular carrier and 5-fluorocytosine (5-FC) as an active agent, released upon the action of intracellular esterases on the ester bond between FA and “trimethyl lock” intramolecular linker, demonstrate good in vitro activity against human pathogenic yeasts of Candida spp. The minimal inhibitory concentrations (MIC) values for the most active conjugates containing caprylic...
-
Entropy function application within the selection process of diagnostic parameters of marine diesel and gas turbine engines
PublikacjaThe paper presents the method of conducting an analysis of the diagnostic informativeness among the parameters characterizing the observed gas dynamic processes carried out within working spaces of marine diesel and gas turbine engines. An entropy function, as the measure of uncertainty of the identified states' set of the engine unfitness was applied. Having evaluated the diagnostic information the most adequate parameters were...
-
Molecular basis of essentiality of early critical steps in the lipopolysaccharide biogenesis in Escherichia coli K-12: requirement of MsbA, cardiolipin, LpxL, LpxM and GcvB
PublikacjaTo identify the physiological factors that limit the growth of Escherichia coli K-12 strains synthesizing minimal lipopolysaccharide (LPS), we describe the first construction of strains devoid of the entire waa locus and concomitantly lacking all three acyltransferases (LpxL/LpxM/LpxP), synthesizing minimal lipid IVA derivatives with a restricted ability to grow at around 21 °C. Suppressors restoring growth up to 37 °C of Δ(gmhD-waaA)...
-
Biopsy needles coated with the antimicrobial coatings
PublikacjaDrug delivery systems are used to achieve higher therapeutic effects of medicaments in a specific diseased site with minimal toxicological effect. The used of biopolymers in drug delivery systems ensure the biocompatibility, biodegradability and low immunogenicity. Drug delivery systems enhance the drug delivery actively and can be used in different diseases. In this study, two types of polymer coatings were prepared and were...
-
The power of silence? opinion contagion and the surprise of the polish 2005 parlamentary and presidential elections
PublikacjaThis paper investigates opinion contagion in collective behaviour using threshold model (Granovetter (1978), Krassa(1988)). The theoretical background is the spiral of silence concept developed by Noelle-Neumann (1974), arguing that people only assert their opinions if they perceive a minimal support from a relevant proportion of others. We apply the model to explain the dispersion between pre-elections preferences and the final...
-
Minimization of the number of periodic points for smooth self-maps of simply-connected manifolds with periodic sequence of Lefschetz numbers
PublikacjaLet f be a smooth self-map of m-dimensional, m ≥ 4, smooth closed connected and simply-connected manifold, r a fixed natural number. For the class of maps with periodic sequence of Lefschetz numbers of iterations the authors introduced in [Graff G., Kaczkowska A., Reducing the number of periodic points in smooth homotopy class of self-maps of simply-connected manifolds with periodic sequence of Lefschetz numbers, Ann. Polon. Math....
-
Comparison of natural frequencies of a circular saw blade obtained empirically and with FEM
PublikacjaThe knowledge of the natural frequencies’ values of circular saw blades is necessary to determine the minimal critical rotational speed in which they can work with required stability. Moreover, testing the circular saw blades with more complicated shapes, e.g. which have additional holes inside blades for cleaning knifes or additional indirect teeth in gullets, reveals some kind of problematic properties of these saw blades. The...
-
Stability of roof trusses stiffened by trapezoidal sheeting and purlins
PublikacjaIn the article linear buckling analysis of a set of steel trusses braced by purlins and trapezoidal sheeting are conducted. The buckling load factor due to the height of a corrugated sheeting profile is investigated in parametric studies. The minimal height of trapezoidal sheeting required for preventing the sheeting and chords of the trusses against the buckling is obtained. Two groups of models are considered: “axial” model as...
-
Simple sufficient condition for subspace to be completely or genuinely entangled
PublikacjaWe introduce a simple sufficient criterion, which allows one to tell whether a subspace of a bipartite or multipartite Hilbert space is entangled. The main ingredient of our criterion is a bound on the minimal entanglement of a subspace in terms of entanglement of vectors spanning that subspace expressed for geometrical measures of entanglement. The criterion is applicable to both completely and genuinely entangled subspaces. We...
-
Edible Lepidoptera as human foods – a comprehensive review
PublikacjaAs the global population continues to grow, traditional protein sources like meat and fish are becoming increasingly unsustainable due to their environmental impact. Edible insects, on the other hand, are highly nutritious, require minimal resources to produce, and emit significantly fewer greenhouse gases than traditional livestock. Lepidoptera, one of the most diverse insect orders, contains some popular edible species that have...
-
Phenotypic consequences of the LYS4 gene disruption in Candida albicans
PublikacjaThe main scientific purpose of our studies was to verify the hypothesis that homoaconitase (HA) from Candida albicans, an enzyme catalyzing a second step of the α-aminoadipate pathway (AAP) of L-Lys biosynthesis may become a new target for antifungal chemotherapy. Previous studies indicated that the A. fumigatus mutant lacking the functional lysF gene, encoding HA, exhibited attenuated virulence in a low-dose mouse infection model...
-
Optymalizacja długości krzywych przejściowych przy budowie i modernizacji linii kolejowych
PublikacjaW drogach szynowych przy obliczaniu długości krzywych przejściowych analizowane są jedynie warunki na ich długość minimalną. Odmienna sytuacja występuje przy projektowaniu dróg, gdzie rozpatrywane są też warunki na długość maksymalną. Spośród nich szczególną rangę ma warunek poprawności geometrycznej układu. W artykule zawarto jego adaptację do specyfiki trasy kolejowej. Sformułowano cel optymalizacji przy obliczaniu długości krzywej...
-
Experimental certification of an informationally complete quantum measurement in a device-independent protocol
PublikacjaMinimal informationally complete positive operator-valued measures (MIC-POVMs) are special kinds of measurement in quantum theory in which the statistics of their d2-outcomes are enough to reconstruct any d-dimensional quantum state. For this reason, MIC-POVMs are referred to as standard measurements for quantum information.Here, we report an experiment with entangled photon pairs that certifies, for what we believe is the first...
-
Scheduling jobs to contain a natural disaster: a model and complexity
Publikacjathis paper is devoted to the problem of scheduling suppression units so that a natural disaster is dealt with as efficient as possible. the concept of deteriorating jobs is adopted, that is, the formal model of scheduling represents linearly increasing value loss as the disaster remains unsuppressed and increasing time for its suppression. more precisely, two different goals are considered: finding a suppression schedule of minimal...
-
Efficient synthesis and antifungal investigation of nucleosides’ quaternary ammonium salt derivatives
PublikacjaQuaternary ammonium salts are a group of compounds with diverse biological properties, the most important of which are their antiviral, antibacterial, and antifungal activities. The quaternization reactions of 5'-O-tosyl derivatives of uridine and thymidine with triethylamine, trimethylamine, 4-(N ,N -dimethylamino)pyridine, 2-methylpyridine, and pyridine are described in this article. Two of the synthesized compounds are exceptional...
-
Evolution of Animats Following a Moving Target in an Artificial Ecosystem
PublikacjaMany biological animals, even microscopically small, are able to track moving sources of food. In this paper, we investigate the emergence of such behavior in artificial animals (animats) in a 2-dimensional simulated liquid environment. These "predators" are controlled by evolving artificial gene regulatory networks encoded in linear genomes. The fate of the predators is determined only by their ability to gather food and reproduce—no...
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015337911]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015332931]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015333131]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015338641]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015336441]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015339081]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Invasive micropapillary carcinoma of breast - Female, 57 - Tissue image [3160630004749761]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015331851]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Invasive micropapillary carcinoma of breast - Female, 57 - Tissue image [3150630005268201]
Dane BadawczeThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [907073001533791]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Liver cell carcinoma - Male, 8 - Tissue image [9070730015336611]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Design, Realization and Measurements of Enhanced Performance 2.4 GHz ESPAR Antenna for Localization in Wireless Sensor Networks
PublikacjaThis paper presents the design, realization and measurements of an Electronically Steerable Parasitic Array Radiator (ESPAR) antenna with enhanced performance of estimating the incoming signal direction. Designed antenna is dedicated for 2.4 GHz ISM applications with emphasis on Wireless Sensor Networks (WSN). Proposed antenna provides different radiation patterns by proper configuration of the parasitic elements. Thus, several...
-
Transport deficiency is the molecular basis of Candida albicans resistance to antifungal oligopeptides
Publikacja(FMDP), an inhibitor of glucosamine-6-phosphate synthase, exhibited growth inhibitory activity against Candida albicans, with minimal inhibitory concentration values in the 0.05–50 mg/L range. Uptake by the peptide permeases was found to be the main factor limiting an anticandidal activity of these compounds. Di- and tripeptide containing FMDP (F2 and F3) were transported by Ptr2p/Ptr22p peptide transporters (PTR) and FMDP-containing...
-
Potential energy surfaces of the low-lying electronic states of the Li+LiCs system
PublikacjaAb initio quantum chemistry calculations are performed for the mixed alkali triatomic system. Global minima of the ground and first excited doublet states of the trimer are found and Born-Oppenheimer potential energy surfaces of the Li atom interacting with the LiCs molecule were calculated for these states. The lithium atom is placed at various distances and bond angles from the lithium-caesium dimer. Three-body nonadditive forces...
-
Antena mikropaskowa o poszerzonym paśmie pracy
PublikacjaW pracy przedstawiono wyniki badań dotyczące anteny mikropaskowej o poszerzonym paśmie pracy. Poprzez zastosowanie układu dwóch szczelin sprzęgających we wspólnej warstwie masy uzyskano 29% pasmo pracy (0.96GHz -1.25 GHz) mierzone przy poziomie WFS < 1.5. Ze względu na obserwowane w charakterystyce promieniowania minima, wykonano drugą wersję anteny ze zmodyfikowanymi wymiarami warstwy masy. Efektemtego zabiegu było uzyskanie anteny...
-
Small cell carcinoma, NOS - Male, 74 - Tissue image [8180729594142021]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Small cell carcinoma, NOS - Female, 68 - Tissue image [12060630017628491]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Small cell carcinoma, NOS - Male, 74 - Tissue image [8180729594149941]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Small cell carcinoma, NOS - Female, 73 - Tissue image [12060630017623461]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
An facile Fortran-95 algorithm to simulate complex instabilities in three-dimensional hyperbolic systems
Dane BadawczeIt is well know that the simulation of fractional systems is a difficult task from all points of view. In particular, the computer implementation of numerical algorithms to simulate fractional systems of partial differential equations in three dimensions is a hard task which has no been solved satisfactorily. Here, we provide a Fortran-95 code to solve...
-
Examining Impact of Speed Recommendation Algorithm Operating in Autonomous Road Signs on Minimum Distance between Vehicles
PublikacjaAn approach to a new kind of recommendation system design that suggests safe speed on the road is presented. Real data obtained on roads were used for the simulations. As part of a project related to autonomous road sign development, a number of measurements were carried out on both local roads and expressways. A speed recommendation model was created based on gathered traffic data employing the traffic simulator. Depending on...
-
The life cycle cost of a building from the point of view of environmental criteria of selecting the most beneficial offer in the area of competitive tendering
PublikacjaThe article analyses environmental and ecological criteria of selecting the most beneficial offer in the aspect of LCC. Construction works contracts and the potential method of defining the above criteria, among others, is pondered on (for example by the recommendation of a material, which is supposed to be used, a ban on substances that are harmful for human health as well for the environment). In the relation to the above, it...
-
Computations of the least number of periodic points of smooth boundary-preserving self-maps of simply-connected manifolds
PublikacjaLet $r$ be an odd natural number, $M$ a compact simply-connected smooth manifold, $\dim M\geq 4$, such that its boundary $\partial M$ is also simply-connected. We consider $f$, a $C^1$ self-maps of $M$, preserving $\partial M$. In [G. Graff and J. Jezierski, Geom. Dedicata 187 (2017), 241-258] the smooth Nielsen type periodic number $D_r(f;M,\partial M)$ was defined and proved to be equal to the minimal number of $r$-periodic points...
-
Music Data Processing and Mining in Large Databases for Active Media
PublikacjaThe aim of this paper was to investigate the problem of music data processing and mining in large databases. Tests were performed on a large data-base that included approximately 30000 audio files divided into 11 classes cor-responding to music genres with different cardinalities. Every audio file was de-scribed by a 173-element feature vector. To reduce the dimensionality of data the Principal Component Analysis (PCA) with variable...
-
E-textbook technologies for academics in medical education
PublikacjaPublic universities in Poland receive fairly limited financial support for creating e-textbooks and lack the appropriate ICT competences among teaching staff, especially in the case of non-technical universities. The authors propose a pedagogical and technological paradigm for e-textbooks in medical education using open source software with minimal IT skills required. Technologies used to develop e-textbooks are connected with:...
-
Quenching of bright and dark excitons via deep states in the presence of SRH recombination in 2D monolayer materials
PublikacjaTwo-dimensional (2D) monolayer materials are interesting systems due to an existence of optically non-active dark excitonic states. In this work, we formulate a theoretical model of an excitonic Auger process which can occur together with the trap-assisted recombination in such 2D structures. The interactions of intravalley excitons (bright and spin-dark ones) and intervalley excitons (momentum-dark ones) with deep states located...
-
Antifungal Activity of Homoaconitate and Homoisocitrate Analogs
PublikacjaThirteen structural analogs of two initial intermediates of the L-alpha-aminoadipate pathway of L-lysine biosynthesis in fungi have been designed and synthesized, including fluoro- and epoxy-derivatives of homoaconitate and homoisocitrate. Some of the obtainedcompounds exhibited at milimolar range moderate enzyme inhibitory properties against homoaconitase and/or homoisocitrate dehydrogenase of Candida albicans. The structural...
-
Quantum origins of objectivity
PublikacjaIn spite of all of its successes, quantum mechanics leaves us with a central problem: How does nature create a bridge from fragile quanta to the objective world of everyday experience? Here we find that a basic structure within quantum mechanics that leads to the perceived objectivity is a so-called spectrum broadcast structure. We uncover this based on minimal assumptions, without referring to any dynamical details or a concrete...
-
Mobile indicators in GIS and GPS positioning accuracy in cities
PublikacjaThe publication describes the possible use of tele-geoprocessing as a synergy of modern IT solutions, telecommunications and GIS algorithms. The paper presents a possibility of urban traffic monitoring with the use of mobile GIS indicators of dedicated monitoring system designed for taxi corporation. The system is based on a stationary and mobile software package. The optimal and minimal assumptions for the monitoring of urban...
-
Antifungal dipeptides incorporating an inhibitor of homoserine dehydrogenase
PublikacjaThe antifungal activity of 5‐hydroxy‐4‐oxo‐L‐norvaline (HONV), exhibited under conditions mimicking human serum, may be improved upon incorporation of this amino acid into a dipeptide structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug...
-
An O ( n log n ) algorithm for finding edge span of cacti
PublikacjaLet G=(V,E) be a nonempty graph and xi be a function. In the paper we study the computational complexity of the problem of finding vertex colorings c of G such that: (1) |c(u)-c(v)|>=xi(uv) for each edge uv of E; (2) the edge span of c, i.e. max{|c(u)-c(v)|: uv belongs to E}, is minimal. We show that the problem is NP-hard for subcubic outerplanar graphs of a very simple structure (similar to cycles) and polynomially solvable for...
-
Sustainable Knowledge Sharing Model for IT Agile Projects
PublikacjaIn order to overcome work environment challenges and remain competitive in the market, organisations must adapt. An organisation's competitiveness can be improved through knowledge sharing; however, improvement without responsibility can have a negative impact on the sociotechnical environment which people cannot fully comprehend. According to researchers, business involvement in sustainable development goals remains minimal [51]....
-
Exploring Stock Traders’ Cognitive Biases: Research Design and Simulator Framework
PublikacjaCognitive bias is a phenomenon that has been extensively studied in stock trading and many other fields. This paper presents a framework for a Mobile Stock Trading Simulator (MSTS) that facilitates automatic investment in stocks with minimal human influence, by investigating the behavioral patterns and cognitive errors of stock market investors. The paper aims to determine whether investors’ investment strategies can be improved...