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Search results for: ANTIMICROBIA ACTIVITY
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Characterization of the Three New Kayviruses and Their Lytic Activity Against Multidrug-Resistant Staphylococcus aureus
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Hyperventilation alters arterial baroreflex control of heart rate and muscle sympathetic nerve activity
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Effect of GO-Fe3O4 and rotating magnetic field on cellular metabolic activity of mammalian cells
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The covalent and non-covalent conjugation of graphene oxide with hydroxycamptothecin in hyperthermia for its anticancer activity
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Air temperature trends at Mount Śnieżka (Polish Sudetes) and solar activity, 1881–2012
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Rapana thomasiana hemocyanin modified with ionic liquids with enhanced anti breast cancer activity
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Variability of Hordeum vulgare L. Cultivars in Yield, Antioxidant Potential, and Cholinesterase Inhibitory Activity
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Changes in Muscle Pattern Activity during the Asymmetric Flat Bench Press (Offset Training)
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The importance of diurnal and nocturnal activity and interspecific interactions for space use by ants in clear-cuts
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Structure–bioavailability relationship study of genistein derivatives with antiproliferative activity on human cancer cell
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Blood–brain barrier permeability mechanisms in view of quantitative structure–activity relationships (QSAR)
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Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats
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Characteristic of antioxidant activity of dry-cured pork loins inoculated with probiotic strains of LAB
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Effect of intensive lipid-lowering therapies on cholinesterase activity in patients with coronary artery disease
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Effect of probiotic bacteria on antiradical activity of peptides isolated from dry-cured loins
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Synthesis of sulfanyl porphyrazines with bulky peripheral substituents – Evaluation of their photochemical properties and biological activity
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In vitro photodynamic activity of lipid vesicles with zinc phthalocyanine derivative against Enterococcus faecalis
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Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors
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Some Common Medicinal Plants with Antidiabetic Activity, Known and Available in Europe (A Mini-Review)
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A Comparison of Muscle Activity Between the Cambered and Standard Bar During the Bench Press Exercise
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Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice
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Distant Non-Obvious Mutations Influence the Activity of a Hyperthermophilic Pyrococcus furiosus Phosphoglucose Isomerase
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Antibacterial activity of core-shell CuxO@TiO2 photocatalyst under UV, vis and dark
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Evaluation of the anti-tyrosinase activity of extracts and rare flavonoids from Scleranthus perennis L.
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Determination of anti-tyrosinase activity of acetone extracts from selected Potentilla L. species.
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Relation between benchmark displacement velocity and seismic activity caused by underground longwall exploitation
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New Life of an Old Drug: Caffeine as a Modulator of Antibacterial Activity of Commonly Used Antibiotics
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The influence of fresh cabbage and sauerkraut juices on the activity of protective enzymes in human cell lines
PublicationMechanizmami przeciwrakotwórczego działania związków zawartych w kapuście jest m.in. metaboliczna aktywacja enzymów II fazy detoksykacji, indukcja enzymów naprawczych DNA oraz aktywnośc przeciwutleniająca. Do enzymów II fazy odtruwania należą m.in. S-transferazy glutationowe (GST) oraz oksydoreduktaza chinonowa NQO1 zwana też DT-diaforazą. GST katalizują reakcję sprzęgania glutationu z wieloma różnymi typami ksenobiotyków, ułatwiając...
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Synthesis and antiproliferative activity of conjugates of adenosine with muramyl dipeptide and nor-muramyl dipeptide derivatives
PublicationWe synthesized a series of MDP(D,D) and nor-MDP(D,D) derivatives conjugated with adenosine through a spacer as potential immunosuppressants. New conjugates were evaluated on two leukemia cell lines (Jurkat and L1210) and PBMC from healthy donors.
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Electrochemical activity and characterization of hybrid material consisted of poly(3,4- ethylenedioxythiophene) and silver hexacyanocobaltate
PublicationPrac przedstawiono charakterystykę elektrochemiczną oraz powierzchniową materiału hybrydowego składającego się z polimeru przewodzącego, poli(3,4-etylenodioksytiofenu) oraz nieorganicznej sieci typu redoks, heksacyjanokobaltanu srebra. Materiał scharakteryzowano technikami jak AFM, SEM. Skład materiału oznaczono za pomocą mikroanalizy rentgenowskiej EDX. Analiza potwierdziła obecność sieci nieorganicznej w materiale. Proporcja...
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photocatalytic activity of silver doped tio2 in vis and uv light, prepared by microemulsion method
PublicationDitlenek tytanu otrzymany w wyniku hydrolizy izopropanolanu tytanu oraz komercyjny katalizator TiO-6 (Catalysis Society of Japan, rutyl, wielkość cząstek 15 nm) zmodyfikowano srebrem metodą mikroemulsyjną. Aktywność fotokatalityczna otrzymanych nanokompozytów Ag-TiO2 została zbadana dla fotodegradacji fenolu pod działaniem promieniowania ultrafioletowego oraz widzialnego. Zaobserwowano, że na efektywność fotorozkładu modelowego...
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Ordered TiO2 nanotubes: the effect of preparation parameters on the photocatalytic activity in air purification process
PublicationVertically ordered TiO2 nanotube arrays were synthesized by anodic oxidation of titanium foil in glycerol, ethylene glycol and water-based electrolytes. The effect of electrolyte composition, anodization voltage, ultrasonic treatment and calcination time on the morphology of the resulting thin films, as well as on their photocatalytic activity in toluene removal, used as a model volatile organic compound, was investigated. Toluene,...
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Comparative Assessment of Bacteriophage and Antibiotic Activity against Multidrug-Resistant Staphylococcus aureus Biofilms
PublicationProblems connected with biofilm-related infections and antibiotic resistance necessitate the investigation and development of novel treatment strategies. Given their unique characteristics, one of the most promising alternatives to conventional antibiotics are bacteriophages. In the in vitro and in vivo larva model study, we demonstrate that phages vB_SauM-A, vB_SauM-C, and vB_SauM-D are effective antibiofilm agents. The exposure...
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Health Enhancing Physical Activity Policies in Poland: Findings from the HEPA PAT Survey
PublicationInsufficient physical activity (PA) is one of major risk factors for serious diseases and premature mortality worldwide. Public policies to enhance PA across society are recognized as an effective tool against the problem. This paper presents the results of a comprehensive assessment of national-level PA policy approach in Poland. A standardized survey of Word Health Organization named the Health-Enhancing Physical Activity Policy...
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Paid work activity and entrepreneurial cognitions of students – evidence from European emerging economies
PublicationPurpose – This paper aims to investigate whether paid work activity (PWA) experience of students from five emerging economies is related to academic results and self-assessment of possessed entrepreneurial traits. Additionally, the authors verify the relationship between obtaining work experience and the willingness to start own business among students. Design/methodology/approach – Participants included 3,631 students of the first...
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The impact of mass-media campaigns on physical activity: a review of reviews through a policy lens
PublicationBackground This review of reviews aimed to: (1) summarize the evidence from published reviews on the effectiveness of mass-media campaigns to promote physical activity (PA) or PA-related determinants (intermediate psychological and proximal outcomes) and (2) to identify policy-relevant recommendations related to successful PA campaigns. Methods An extensive literature search was performed on 1 March 2021. Reviews that evaluated...
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Sustainable Urban Mobility Plans: implementation process and indicators to evaluate effects on physical activity
PublicationBackground: Active mobility and public transport increase physical activity (PA) levels. With varying intensity and effectiveness, European cities implement Sustainable Urban Mobility Plans (SUMPs) to spur transport-related PA. Therefore, we aim to examine drivers and barriers to SUMP implementation and assess its influence on PA across European cities. Methods: We screened policy reports to gain insights into SUMP implementation...
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The Effect of Titanium Oxyfluoride Morphology on Photocatalytic Activity of Fluorine-Doped Titanium(IV) Oxide
PublicationTitanium oxyfluoride (TiOF2) is a metastable product that can be obtained in a fluorine-rich environment. This material can also be a valuable precursor in the synthesis of titanium(IV) oxide (TiO2). However, the effect of TiOF2 morphology on the physicochemical properties of TiO2 has not been studied so far. In this work, single-phase TiOF2 was prepared by a solvothermal method. The as-synthesized samples exhibited a variety of...
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Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values
PublicationWith the current massive increases in drug-resistant microbial infection as well as the significant role of fungal infections in the death toll of COVID-19, discovering new antifungals is extremely important. Natural and synthetic xanthones are promising derivatives, although only few reports have demonstrated their antifungal mechanism of action in detail. Newly synthetized by us xanthone derivative 44 exhibited strong antifungal...
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Preparation, characterization and anti-colitis activity of curcumin-asafoetida complex encapsulated in turmeric nanofiber
PublicationUlcerative colitis (UC) is a main form of inflammatory bowel disease (IBD). Asafoetida (ASF) and turmeric have traditionally been used for the treatment of various inflammatory diseases, including UC, because ASF is rich in sulfur compounds and turmeric contains curcumin (CUR). Turmeric nanofiber (TNF), the modified cell wall component of turmeric is considered to play important role in the human diet, health and can be used as...
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Chemical modification of natural immunomodulators tuftsin and muramyl dipeptide significantly influence their biological activity
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Synthesis, structure, DNA binding and anticancer activity of mixed ligand ruthenium(II) complex
PublicationIn order to obtain a potential chemotherapeutic which is not affected on the normal BALB/3T3 cell line, a new arene ruthenium(II) complex {[RuCl(L1)(η6-p-cymene)]PF6}2 · H2O has been synthesized by a direct reaction of precursor, [{(η6-p-cymene)Ru(μ-Cl)}2Cl2], with N,N-chelating ligand (L1 - 2,2′-bis(4,5-dimethylimidazole). The compound has been fully characterized by elemental analysis, X-ray diffraction, IR, UV–Vis and 1H, 13C...
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Antibacterial Activity and Cytocompatibility of Bone Cement Enriched with Antibiotic, Nanosilver, and Nanocopper for Bone Regeneration
PublicationBacterial infections due to bone replacement surgeries require modifications of bone cement with antibacterial components. This study aimed to investigate whether the incorporation of gentamicin or nanometals into bone cement may reduce and to what extent bacterial growth without the loss of overall cytocompatibility and adverse effects in vitro. The bone cement Cemex was used as the base material, modified either with gentamicin...
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Optical activity and electro-optic effect of l-arginine doped KDP single crystals
PublicationWe have used the modified polarimetric methods to study optical activity (OA) in the potassium dihydrogenphosphate (KDP) crystals doped with 0.7, 1.4 and 3.8 wt% L-arginine (L-arg) amino acid. Crystals were grown by the temperature reduction method. Small changes of the absolute eigen waves ellipticity and OA values in doped crystals were noted. We have experimentally determined the signs of OA in the [1 00] and [01 0] directions...
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A strategy for GPS data processing in a precise local network during high solar activity
PublicationThis paper presents the analyses connected with reduction of errors from ionospheric refraction using GPS data from local satellite networks. This is particularly essential during rising solar activity. The Bernese GPS Software v. 4.2 was used, as an analytical tool. The test data included measurements from a geodynamic network SUDETES situated in the Sudety Mountains across the border between the Czech Republic and Poland. A local...
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Ultrasonic-assisted Electrodeposition of Cu-Sn-TiO2 Nanocomposite Coatings with Enhanced Antibacterial Activity
PublicationCopper-based coatings are known for their high antibacterial activity. In this study, nanocomposite Cu–Sn–TiO2 coatings were obtained by electrodeposition from an oxalic acid bath additionally containing 4 g/dm3 TiO2 with mechanical and ultrasonic agitation. Ultrasound treatment was performed at 26 kHz frequency and 32 W/dm3 power. The influence of agitation mode and the current load on the inclusion and distribution of the TiO2...
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The evidence for the impact of policy on physical activity outcomes within the school setting: A systematic review
PublicationPurpose Despite the well-established health benefits of physical activity (PA) for young people (aged 4–19 years), most do not meet PA guidelines. Policies that support PA in schools may be promising, but their impact on PA behavior is poorly understood. The aim of this systematic review is to ascertain the level and type of evidence reported in the international scientific literature for policies within the school setting that...
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The Influence of External Additional Loading on the Muscle Activity and Ground Reaction Forces during Gait
PublicationAsymmetrical external loading acting on the usculoskeletal system is generally considered unhealthy. Despite this knowledge, carrying loads in an asymmetrical manner like carrying on one shoulder, with one hand, or on the strap across the torso is a common practice. This study is aimed at presenting the effects of the mentioned load carrying methods on muscle activity assessed by using thermal field and ground reaction forces....
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Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity
PublicationSeven conjugates composed of well-known fluoroquinolone antibacterial agents, ciprofloxacin (CIP) or levofloxacin (LVX), and a cell-penetrating peptide transportan 10 (TP10-NH2) were synthesised. The drugs were covalently bound to the peptide via an amide bond, methylenecarbonyl moiety, or a disulfide bridge. Conjugation of fluoroquinolones to TP10-NH2 resulted in congeners demonstrating antifungal in vitro activity against human...
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Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: synthesis and anticancer activity evaluation
PublicationA new series of N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives 4-21 have been synthesized, and evaluated at the National Cancer Institute (USA) for their in vitro activities against a panel of 60 different human cancer cell lines. Among them, compounds 16, 20 and 21 exhibited remarkable cytotoxic activity against numerous human cancer cell lines. We found that sulfonamide derivative 21 appeared to be more selective...