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Search results for: GENOME EDITING

  • Hybrid approach to ontology specification and development

    Publication

    In this chapter a first draft of a hybrid ontology development approach is presented. The context of this method encompasses the multi-agent system equipped with knowledge bases and inferring engine. The process of ontology engineering appears as a complex issue, as it addresses different point-views of both, a client and a modeler with a requirements/system analyst. Regarding this, an approach based on the knowledge preprocessing...

  • A new prototype of piezoelectric bending resonant transducer for analysis of soft tissues properties

    Publication

    This paper is devoted to a new piezoelectric bending resonant transducer prototype dedicated to the characterization of the mechanical properties of soft tissue. A general description of the actuator’s structure is presented including the basic principles of the measurement. The chosen geometry of the prototype is discussed and compared with the existing version. Constitutive equations are presented for the active and passive layer...

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  • Smart Cities Concept: Smart Mobility Indicator

    Publication

    - CYBERNETICS AND SYSTEMS - Year 2019

    This work attempts to analyze problems resulting from the lack of possibility to assess the effectiveness of the implementation of “Smart Mobility” solutions, which represent one of the cornerstones of Smart Cities, from the point of view of city hall offices. The work presents existing Smart Mobility evaluation solutions, discusses their drawbacks, and then proposes a new indicator. The final part of the work presents assumptions...

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  • Design and simulation of a new prototype of piezoelectric cantilever sensor/actuator for analysis of the soft tissues properties

    This paper is devoted to a new prototype of piezoelectric cantilever transducer dedicated for the characterization of the mechanical properties of soft tissues. General description of the actuator’s structure is presented including the basic principles of the measurement. The chosen geometry of the prototype is discussed and compared with the existing one. Constitutive equations are presented for the active and passive layer of...

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  • Dynamic Content Internationalization in Web Applications

    Publication

    - Year 2013

    This paper shows a concept for providing dynamic internationalization to web applications. Presented work is based on the Java Web Platform but described concepts can be successfully implemented on other platforms. It shows how textual data being part of web pages static and dynamic content can be localized dynamically during application runtime. All concepts presented were or are still being developed in an existing conference...

  • Accelerometer-based Human Activity Recognition and the Impact of the Sample Size

    Publication

    The presented study focused on the recognition of eight user activities (e.g. walking, lying, climbing stairs) basing on the measurements from an accelerometer embedded in a mobile device. It is assumed that the device is carried in a specific location of the user’s clothing. Three types of classifiers were tested on different sizes of the samples. The influence of the time window (the duration of a single trial) on selected activities...

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  • Current risk analysis and management issues in technical systems.

    Dealing with the reliability and safety of industrial hazardous plants requires taking into account relevant interdisciplinary scientific knowledge and some existing approaches based on so-called good engineering practice, also those included in the international standards and guidelines. In this article an approach is proposed how to integrate the functional safety concept with information security aspects in the design and management...

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  • Dynamic ranking of cloud providers

    Publication

    - Year 2012

    The paper focuses on how to create an effective dynamic ranking service for IaaS,PaaS and SaaS cloud providers. It considers building of a quality model for thispurpose along with definition of quality measurement procedures. The paper discussesseveral techniques known from already existing price comparison engines that couldbe modified and adopted for comparison of cloud providers. Furthermore, a tech-nique for filtering measured...

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  • Modeling of the internal combustion engine cooling system

    Publication

    The article concerns computer modelling of processes in cooling systems of internal combustion engines. Modelling objectives and existing commercial programs are presented. It also describes Author’s own method of binding graphs used to describe phenomena in the cooling system of a spark ignition engine. The own model has been verified by tests on the engine dynamometer. An example of using a commercial program for experimental...

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  • Fungal Typin Methods

    Publication

    The broad application of the molecular techniques in mycoses diagnosis is related to increase of infections caused by fungi in many countries. The oldest typing methods relaying on fenotypic observation, physiological and biochemical examination have had very limited importance from decades. Novadays, the molecular biology methods took their place. Most of the genotyping methods have been devoleped to be applied for typing of bacteria...

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  • Features of irregularity in examples of Polish multi-family architecture constructed in 2011–2021 and nominated for the Mies van der Rohe award

    Publication

    This article is devoted to the analysis of contemporary Polish multi-family architecture in the context of aesthetic irregularity. The research was limited to constructions from 2011–2021 and nominated for the Mies van der Rohe award as the objects with the greatest potential impact on shaping further trends. In their research, the authors focused on searching for the features of irregularities, which, in their opinion, have become...

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  • Security Evaluation of IT Systems Underlying Critical Networked Infrastructures

    Publication

    - Year 2008

    Critical infrastructures have become highly dependent on information and communication technology (ICT). The drawback of this situation is that the consequences of disturbances of the underlying ICT networks may be serious as cascading effects can occur. This raises a high demand for security assurance, with a high importance assigned to security evaluations. In this paper we present an experiment-centric approach for the characterisation...

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  • Android OS: A Review

    Publication

    Due to the technological development, mobile terminals have evolved into functionally sophisticated devices such as smartphones and tablets. The Android platform has become one of the most popular operating system with millions of new users each year. Despite many studies, none have provided a comprehensive description of this operating system. In this paper we present a review of the Android OS. We describe the platforms history...

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  • Functionalization of Parylene During Its Chemical Vapor Deposition

    Publication

    - JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY - Year 2011

    Two possible mechanisms for the reaction of four halogenated (metha)acrylate-based molecules with Parylene [poly (paraxylylene)] during its chemical vapor deposition were proposed. The chemical reactivity of acrylate double bond with the paraxylylene biradical was calculated for all four (metha)acrylate-based molecules. These calculations allowed the evaluation of the energetically favorable mechanism and indeed a direct correlation...

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  • Combined reversible switching of ECD and quenching of CPL with chiral fluorescent macrocycles

    Publication
    • A. Homberg
    • E. Brun
    • F. Zinna
    • S. Pascal
    • M. Górecki
    • L. Monnier
    • C. Besnard
    • G. Pescitelli
    • L. Di
    • J. Lacour

    - Chemical Science - Year 2018

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  • Simulation-Driven Antenna Modeling by Means of Response Features and Confined Domains of Reduced Dimensionality

    Publication

    In recent years, the employment of full-wave electromagnetic (EM) simulation tools has become imperative in the antenna design mainly for reliability reasons. While the CPU cost of a single simulation is rarely an issue, the computational overhead associated with EM-driven tasks that require massive EM analyses may become a serious bottleneck. A widely used approach to lessen this cost is the employment of surrogate models, especially...

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  • Deep eutectic solvents with solid supports used in microextraction processes applied for endocrine-disrupting chemicals

    The determination of endocrine-disrupting chemicals (EDCs) has become one of the biggest challenges in Analytical Chemistry. Due to the low concentration of these compounds in different kinds of samples, it becomes necessary to employ efficient sample preparation methods and sensitive measurement techniques to achieve low limits of detection. This issue becomes even more struggling when the principles of the Green Analytical Chemistry...

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  • Nanomaterials for photothermal and photodynamic cancer therapy

    Publication
    • B. Nasseri
    • E. Alizadeh
    • F. Bani
    • S. Davaran
    • A. Akbarzadeh
    • N. Rabiee
    • A. Bahadori
    • M. Ziaei
    • M. Bagherzadeh
    • M. Saeb... and 2 others

    - Applied Physics Reviews - Year 2022

    In recent years, the role of optically sensitive nanomaterials has become powerful moieties in therapeutic techniques and has become particularly emphasized. Currently, by the extraordinary development of nanomaterials in different fields of medicine, they have found new applications. Phototherapy modalities, such as photothermal therapy (PTT) by toxic heat generation and photodynamic therapy (PDT) by reactive oxygen species, are...

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  • Verification of the criteria for evaluation of water and frost resistance of asphalt concrete

    The paper presents the results of field investigation - condition survey of existing pavements and the results of laboratory tests on water and frost resistance of samples cored from the these pavements. The purpose of testing was to verify the criteria for evaluation of the resistance of asphalt concrete to the action of water and frost by way of comparing the results of field and laboratory tests, followed by evaluation of their...

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  • From Regenerative Buildings to Regenerative Urban Projects: Design frameworks to scale up within the area of regenerative practice

    Publication

    - Year 2021

    In this chapter, a discussion will be presented of design frameworks and assessment tools that are useful for boosting the scale jumping of regenerative design practices and the paradigm shift. Our main objectives will be to identify existing design and assessment frameworks, to describe the way they work and how they can contribute to scale-jumping regenerative design, as well as to identify shortcomings and opportunities. We...

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  • Review of historical buildings' foundations

    Publication

    - GEOTECHNIQUE - Year 2005

    The paper presents in brief the history of foundation engineering with a particular regard to its development, applied techniques and materials. Different types of old foundations in relation to various soil conditions are considered. Basic methods of preservation of old foundations, with special emphasis given to their faults and advantages are discussed. Finally, some problems of the reuse of pre-existing foundations are raised....

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  • Wpływ drążenia pionowego w silikatowych elementach murowych na nośność kotew wklejanych

    Publication

    The article is showing results of measurements of the effectiveness of the assembly anchor of inmates glued in in sunk vertically lime-sandy blocks. Examinations were performed for cases of the assembly anchor in different fragments of blocks: in part fullwall, in an axis of symmetry and on the edge of the aperture vertical. An influence of the location of places of settling was examined anchor to the way of the forming of uniting...

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  • Analysis of Rolling Resistance of Tires With Run Flat Insert

    Publication

    - Key Engineering Materials - Year 2014

    Run flat properties are required for tires intended for special applications like military or rescue vehicles. Run-Flat inserts make possible to drive a car or truck, with certain restrictions, also when inflation pressure is very low or non-existing (after tire damage). Rolling resistance of tires rolling the inserts increases considerably in relation to the rolling resistance of properly inflated tires. This paper presents results...

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  • Modelling Evolution of Knowledge-Based Information Technology Organization: The Concept and Perspective

    Publication

    - SYSTEMS SCIENCE - Year 2010

    Increasing pressure on improving the efficiency of companies' operations leads to transformation of their Information Technology (IT) organizations from technology-oriented to service-oriented, based on the Information Technology Infrastructure Library (ITIL) model. The evolution of these IT organizations can be supported by the knowledge-based systems centered on the rules determined through agregation and refinement of existing...

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  • NOBLE METAL MODIFIED TiO2 FOR PHOTOCATALYTIC AIR PURIFICATION

    Publication

    TiO2 was surface modified with silver, gold, palladium and platinum ion clusters to improve its photocatalytic activity. The effect of metal content, the kind of dopant used during preparation procedure on the photoactivity were investigated. in toluene removal which was used as a model volatile organic compound. Toluene, at the concentration of about 100 ppm, was irradiated over noble metal modified TiO2 using light-emitting diodes...

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  • Digital Control System of the Wavemaker in the Towing Tank

    The paper describes a digital control system of the rigid flap wavemaker in a towing tank in CTO S.A. Ship Design and Research Centre. The control system is based on an 8-bit AVR microcontroller and consists of two cascading PID controllers. The digital system replaced the previous analogue system from 1974 and has been integrated with the existing sensors and actuators of the wavemaker. The new control system allows to obtain...

  • A study of the photoelectron spectra of α-tetrahydrofurfuryl alcohol over the outer valence energy region (9–25 eV)

    Publication

    - CHEMICAL PHYSICS LETTERS - Year 2017

    Photoelectron spectra of α-tetrahydrofurfuryl alcohol (THFA) molecules, the threshold spectrum and spectra for constant photoelectron energies, have been measured over the photon energy range 9–25 eV. Analysis of the photoelectron spectra has allowed overlapping photoionization bands to be separated, tentatively assigned and their vertical photoionization energies to be determined. These energies are compared with existing theoretical...

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  • Comparison of soil models in the thermodynamic analysis of a submarine pipeline buried in seabed sediments

    Publication

    This paper deals with mathematical modelling of a seabed layer in the thermodynamic analysis of a submarine pipeline buried in seabed sediments. The existing seabed soil models: a “soil ring” and a semi-infinite soil layer are discussed in a comparative analysis of the shape factor of a surrounding soil layer. The meaning of differences in the heat transfer coefficient of a soil layer is illustrated based on a computational example...

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  • From Sequential to Parallel Implementation of NLP Using the Actor Model

    The article focuses on presenting methods allowing easy parallelization of an existing, sequential Natural Language Processing (NLP) application within a multi-core system. The actor-based solution implemented with the Akka framework has been applied and compared to an application based on Task Parallel Library (TPL) and to the original sequential application. Architectures, data and control flows are described along with execution...

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  • Safeguarding democracy during pandemics. Social distancing, postal, or internet voting—the good, the bad, or the ugly?

    Publication

    - PUBLIC MONEY & MANAGEMENT - Year 2021

    During a pandemic, many countries and organizations must decide whether to postpone upcoming elections or to hold them (Krimmer et al., 2020a). If the decision is made to hold the election, three main scenarios come to mind: continue using the existing system but include measures to ensure the health of participants; or look for alternatives among remote voting channels which could ensure social distancing is guaranteed either...

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  • Influence of Thermal Imagery Resolution on Accuracy of Deep Learning based Face Recognition

    Publication

    Human-system interactions frequently require a retrieval of the key context information about the user and the environment. Image processing techniques have been widely applied in this area, providing details about recognized objects, people and actions. Considering remote diagnostics solutions, e.g. non-contact vital signs estimation and smart home monitoring systems that utilize person’s identity, security is a very important factor....

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  • Białka prokariotycznego systemu MMR: rola oraz interakcje

    Uszkodzenia komórkowego DNA w postaci błędnie sparowanych lub niesparowanych zasad azotowych są wynikiem niewłaściwie zachodzących procesów metabolizmu DNA, takich jak replikacja, rekombinacja oraz naprawa DNA. Utrwalenie tego rodzaju zmian prowadzi do powstania mutacji. System MMR (ang. DNA mismatch repair) usuwa te uszkodzenia przyczyniając się do zwiększenia wierności replikacji DNA oraz utrzymania stabilności genomu komórki....

  • Changing Attitudes in Cross Cultural Diversity through International Senior Capstone Projects

    Publication

    - Year 2015

    In this global world, today’s engineer is likely to have to work in global international teams with colleagues from other nationalities. The challenge for many engineering curricula is how to include, in a realistic way, this global dimension and increase the student’s awareness of the issues that are encountered. In the Purdue University Engineering Technology program, an international capstone project was created to increase...

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  • Computer-Aided Diagnosis of COVID-19 from Chest X-ray Images Using Hybrid-Features and Random Forest Classifier

    Publication

    - Healthcare - Year 2023

    In recent years, a lot of attention has been paid to using radiology imaging to automatically find COVID-19. (1) Background: There are now a number of computer-aided diagnostic schemes that help radiologists and doctors perform diagnostic COVID-19 tests quickly, accurately, and consistently. (2) Methods: Using chest X-ray images, this study proposed a cutting-edge scheme for the automatic recognition of COVID-19 and pneumonia....

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  • Od Safony do Sibylli : o twórczości kobiet, które miały odwagę zmieniać świat

    Publication

    - Year 2015

    "From Sappho to Sibylla. About the women’s research and literary output preserved in the PAS Gdańsk Library early printed books collection (15th-18th c.)" The main purpose of this study was to present women’s research and literary output preserved in the early printed books collection (15th-18th c.) of the PAS Gdańsk Library (PAN Biblioteka Gdańska). The author mentions the phenomenon of women writing and participation in the...

  • Historic Urban Settings, LED Illumination and its Impact on Nighttime Perception, Visual Appearance, and Cultural Heritage Identity

    Publication

    - Year 2018

    Many cities, towns and villages around the world have adopted new Lighting Emitting Diode (LED) technology in order to save energy, operational and maintenance costs. While energy-efficient, these light sources have a critical effect on the appearance of historic sites at night and the technology has unique properties and numerous inherent drawbacks that present challenges to decision makers as well as inexperienced lighting...

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  • A study on the interaction of rhodamine B with methylthioadenosine phosphorylase protein sourced from an Antarctic soil metagenomic library.

    Publication

    - PLOS ONE - Year 2013

    The presented study examines the phenomenon of the fluorescence under UV light excitation (312 nm) of E. coli cells expressing a novel metagenomic-derived putative methylthioadenosine phosphorylase gene, called rsfp, grown on LB agar supplemented with a fluorescent dye rhodamine B. For this purpose, an rsfp gene was cloned and expressed in an LMG194 E. coli strain using an arabinose promoter. The resulting RSFP protein was purified...

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  • Genetic and Epigenetic Aspects of Atopic Dermatitis

    Publication
    • B. Nedoszytko
    • E. Reszka
    • D. Gutowska-Owsiak
    • M. Trzeciak
    • M. Lange
    • J. Jarczak
    • M. Niedoszytko
    • E. Jablonska
    • J. Romantowski
    • D. Strapagiel... and 6 others

    - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2020

    Atopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with mutations in genes encoding epidermal structural proteins, barrier enzymes, and their inhibitors; the role of genes regulating innate and adaptive immune responses and environmental factors inducing the disease is also noted. Recent studies point to the key role of epigenetic changes in the development of the disease. Epigenetic modifications...

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  • Collective creativity in management science

    Purpose: The purpose of this paper is to establish the current state of knowledge on collective creativity in management science on the basis of a systematic literature review. Methodology: A systematic review was performed based on the three-step SPL procedure proposed by Tranfield et al. (2003). Two databases (Scopus and Web of Science) were searched electronically up until March 2022. Based on the secondary data a literature...

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  • Greencoin information system empowering urban adaptability and eco living choices.

    There are many gamification projects focused on mitigating climate changes which has been tested or implemented worldwide. However, the gap which remains is the limited number of solutions dedicated for central European countries where the urban polices in terms of climate vulnerability are bounded. On the other hand, cities, when implementing climate-oriented policies, are focused on urban resilience, while the opportunities...

  • Innovative Urban Blue Space Design in a Changing Climate: Transition Models in the Baltic Sea Region

    Publication

    - Water - Year 2023

    Waterfront areas in cities are subject to constant changes. The desire to integrate the transformed waterside areas with the urban fabric involves shaping high-quality public spaces related to water, which are often referred to as urban blue spaces (UBS). The aim of the research was to examine the transformation processes of urban waterfront areas in the Baltic Sea Region and identify emerging transition models and types of blue...

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  • Zastosowanie audytu wewnętrznego u operatorów produkcyjnych w zapobieganiu kryzysom-studium przypadku

    Głównym tematem artykułu była analiza badań przeprowadzonych u producenta farb proszkowych przedsiębiorstwa X, w zakresie zastosowania audytu wewnętrznego, jako metody pozwalającej na zapobieganie pojawienia się kryzysu. Właściwa współpraca operatorów produkcyjnych z menedżerami ma kluczowe zna-czenie dla budowy właściwej pozycji audytu wewnętrznego w przedsiębiorstwie X. Brak należytej współpracy na etapie badań, przy braku...

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  • Stability of roof trusses stiffened by corrugated sheets

    Publication

    - Year 2010

    The present parametric study is devoted to the stability analysis of a set of trusses stiffened by decking of corrugated steel sheets. For different parameters of corrugated sheets the critical loading of the roof is calculated. In the parametrical analysis the threshold bracing condition of the roof is obtained. Then the geometrically non-linear analysis of trusses braced by corrugated sheets was conducted. As a results of non-linear...

  • Pulse-Width Modulation of Power Electronic DC–AC Converter

    Publication

    - Year 2021

    The Second Edition of High Performance Control of AC Drives with Matlab®/Simulink delivers an updated and thorough overview of topics central to the understanding of AC motor drive systems. The book includes new material on medium voltage drives, covering state-of-the-art technologies and challenges in the industrial drive system, as well as their components, and control, current source inverter-based drives, PWM techniques for...

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  • Fuzzy Methods and Models for a Team-Building Process

    Publication

    - Year 2014

    This chapter contains an introduction to fuzzy-logic model-based approaches for a team-building process. Such appraches allow extending typical recruiting practice and selection processes to enable a wider and more precise assessment of a new team and/or existing team members, taking into account both their hard and soft skills. Moreover, as effectiveness of teams depends on the interpersonal skills and emotional intelligence...

  • Power electronic systems as a crucial part of Smart Grid infrastructure - a survey

    Publication

    - Bulletin of the Polish Academy of Sciences-Technical Sciences - Year 2012

    This article gives a tutorial overview of the most important issues related to the use of power electronic systems in power engineering, with respect to the urgent need for modernization of existing grids in the direction of intelligent networks. The main problems and conditions bound up with the construction of Smart Grids and the location, as well as functioning in them of the most important power electronic systems are presented...

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  • Towards facts extraction from text in Polish language

    Publication

    Natural Language Processing (NLP) finds many usages in different fields of endeavor. Many tools exists allowing analysis of English language. For Polish language the situation is different as the language itself is more complicated. In this paper we show differences between NLP of Polish and English language. Existing solutions are presented and TEAMS software for facts extraction is described. The paper shows also evaluation of...

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  • Recovery and Management of Postindustrial Spaces in the City on Selected Examples od European Implementations

    Publication

    Undeveloped, neglected and then abandoned post-industrial areas often located in a short distance from city centers have become, on one hand a major problem for city stewards due to the formation of dead urban tissue disturbing the continuity and cohesion of urbanized areas, on the other hand are spaces with high potential for a good location. The article aims to formulate, from the architectural and urban perspective, an answer...

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  • Towards Extending Wikipedia with Bidirectional Links

    Publication

    In this paper, we present the results of our WikiLinks project which aims at extending current Wikipedia linkage mechanisms. Wikipedia has become recently one of the most important information sources on the Internet, which still is based on relatively simple linkage facilities. A WikiLinks system extends the Wikipedia with bidirectional links between fragments of articles. However, there were several attempts to introduce bidirectional...

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  • Homoclinic and Heteroclinic Orbits for a Class of Singular Planar Newtonian Systems

    Publication

    - Year 2015

    The study of existence and multiplicity of solutions of differential equations possessing a variational nature is a problem of great meaning since most of them derives from mechanics and physics. In particular, this relates to Hamiltonian systems including Newtonian ones. During the past thirty years there has been a great deal of progress in the use of variational methods to find periodic, homoclinic and heteroclinic solutions...