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Search results for: p-glikoproteina
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Screening of potential inhibitors for COVID-19 main protease from phytoconstituents of Tectona grandis Linn: application of molecular modeling studies
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New approach in determination of urinary diagnostic markers for prostate cancer by MALDI-TOF/MS
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Electronic and lattice properties of noncentrosymmetric superconductors ThTSi (T=Co, Ir, Ni, and Pt)
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Effect of high pressure and sub-zero temperature on some gram-negative bacteria.
PublicationCelem pracy było określenie przeżywalności wybranych gramujemnych bakterii na działanie wysokiego ciśnienia i ujemnej temperatury. Traktowanie komórek bakterii ciśnieniem 193 MPa w temperaturze -20C przez 24 godziny, powodowało całkowitą inaktywację bakterii E. coli, P. fluorescens i T. thermophilus. Po działaniu ciśnienia przez krótszy czas występowały różnice we wrażliwości między badanymi szczepami. Najmniej odporny na działanie...
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A theoretical framework for understanding trust and distrust in internet voting
PublicationEach and every case of success and failure in the implementation of internet voting is permeated by a common element: the concept of trust. Several researchers highlighted the relevance of creating trust for the successful implementation of technology [15] and, in particular, of internet voting [13]. But the concept itself is complex and challenging to define, for one fundamental reason: it is a concept of everyday social use...
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Udział polskich studentów przedwojennej Politechniki Gdańskiej w odbudowie nauki i przemysłu Wybrzeża
PublicationNapisanie niniejszego artykułu wiąże się bezpośrednio z przypadającąw tym roku 100. rocznicą powstania 29 czerwca 1921 roku KorporacjiAkademickiej ZAG Wisła, której tradycje sięgają okresu sprzed I wojnyświatowej, kiedy to w 1913 roku utworzono pierwszą na PolitechniceGdańskiej, tajną, polską organizację studencką Związek AkademikówGdańskich. W 1921 roku powstała także Bratnia Pomoc Zrzeszenia
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Configurational and Conformational Preferences in Stereoselective Acylations of N-Methyl-1,3-diaminopropane with Acyl Chlorides
PublicationEvidence for a stereoinduction profile of the reaction of N-methyl-1,3-diaminopropane with acyl chlorides was provided. A possibility to engage in intramol. CH2···HN and Cl···H-N interactions and the proton migration process to the methylamino group leads to the E secondary amides carrying the N···H+···N or N-H···N bridges, that show unusual spectroscopic images. Empirical relations between the ΔδC chem. shift differences,...
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Chromogenic macrocyclic derivatives of azoles - synthesis and properties,
PublicationNew azocrown ethers comprising imidazoles in the macrocycle have been synthesized. Imidazole, 2-methyl-, 4-methyl-, and 4-phenylimidazole were incorporated to form macrocyclic units by coupling with the appropriate bis-diazonium salts. The syntheseswere performed under high dilution conditions. The X-ray structure of a water adduct of the 21-membered crown ether derivative of 4-methylimidazole 8 has been solved. Metal...
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Azomacrocyclic derivatives of imidazole: synthesis, structure, and metal ion complexation properties
PublicationNew azocrown ethers comprising imidazoles in the macrocycle have been synthesized. Imidazole, 2-methyl-, 4-methyl-, and 4-phenylimidazole were incorporated to form macrocyclic units by coupling with the appropriate bis-diazonium salts. The syntheseswere performed under high dilution conditions. The X-ray structure of a water adduct of the 21-membered crown ether derivative of 4-methylimidazole 8 has been solved. Metal...
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4-(Cyclic-amidino)phenols. Preparation and Use in a Diamidine Synthesis
PublicationThe Pinner synthesis was applied to the prepn. of phenols 4-substituted with cyclic amidines in high yields from readily available 4-HOC6H4C(OMe):NH.HCl and aliph. diamines. An alternative attempt was made to convert 4-HOC6H4CSNH2 to 4-(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)phenol. A procedure for the prepn. of 3,6-bis(4-hydroxyphenyl)-1,2,4,5-tetrazine is reported. The syntheses of 2,4-bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pyrimidine...
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Physical and Mechanical Evaluation of Silicone-Based Double-Layer Adhesive Patch Intended for Keloids and Scar Treatment Therapy
PublicationGrowing interest in silicone elastomers for pharmaceutical purposes is due to both theirbeneficial material effect for scar treatment and their potential as drug carriers. Regarding their morphological structure, silicone polymers possess unique properties, which enable a wide range of applicability possibilities. The present study focused on developing a double-layer adhesive silicone film (DLASil) by evaluating its physical...
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VERSATILE SPACE OF PERSIAN COURT HOUSE IN ISFAHAN USED AS POLISH CHILDREN HABITAT DURING THE WW2
PublicationDuring WW2 thousands of Polish citizens were deported to Siberia and Kazakhstan in the USSRdoomed to exterminating labour. The Polish army was also detained there. The Iranian Shahallowed Polish soldiers and civilians to cross from Russia to Iran. In Isfahan Polish fugitives, mainlychildren, were accommodated in Persian traditional court houses which were converted into theirtemporary habitat, where new...
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Preliminary typology and contextual analysis of Roman and late antique cooking wares from the Roman rural settlement at Podšilo bay on the island of Rab (north–eastern Adriatic, Croatia)
PublicationThe paper presents a preliminary typology of coarse cooking ware from the Roman/late antique layers of the rural settlement at Podšilo bay on the island of Rab. The vessels have been associated with several basic shapes and divided by types, while fabrics have been described macroscopically. Analogies and a contextual analysis were used to propose dating and to assess provenience for well-known ware classes or to define areas...
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Preparation and some properties of multiblock copoly(amide-b-amide)s
PublicationThe paper concerns the polymers built of oligoamide hard blocks and oligoamide soft blocks (KPAA, formula I). Oligo(laurolactam) (PA12) was used as hard block and the product of reaction of dimerized fatty acid and hexamethylene diamine (PA6,36) was used as a soft one. Effects of molar ratio of these blocks on the following properties of KPAA have been investigated: limiting viscosity number ([2]), degrees of swelling in water...
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Infedeltà nel trasferimento delle collocazioni nella traduzione dei romanzi di Michel Houellebecq dal francese all’italiano
PublicationBuilding on my PhD project, this paper explores fidelity challenges in the transfer of verb-nominal collocations (VNC) in the Italian translations of seven of Michel Houellebecq’s novels. I examine various kinds of infidelity, such as omissions, errors, incongruence in constituent transmission, incoherence in recurrent VNC transmission, and infidelity at the level of phraseological coverage. The accurate transfer...
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Dylematy zarządzania adaptacyjnego projektem w przedsiębiorstwie mediowym
PublicationArtykuł dotyczy zarządzania mediami, dlatego odpowiednio zaprezentowano próbę możliwego podejścia opartego na zwinnych metodologiach zarządzania projektami. Artykuł przedstawia kolejno media i zarządzanie nimi (przegląd literatury), charakterystykę projektów mediowych, zwinne zarządzanie projektami, analizę zwinnego podejścia i zarządzania mediami wraz z propozycją nowego pomysłu, jakim jest zwinne zarządzanie mediami (Agile...
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Środowiskowe aspekty wdrażania koncepcji lean manufacturing
PublicationZ uwagi na rosnące zainteresowanie tematyką nowoczesnego i niskokosztowego zarządzania środowiskowego w artykule przedstawiono główne obszary wykorzystania narzędzi Lean Manufacturing w procesie doskonalenia zarządzania środowiskowego w przedsiębiorstwach produkcyjnym. Zdefiniowano pojęcie aspektu środowiskowego w ujęciu wymagań normy ISO14001. Opisano budowę środowiskowej wartości dodanej Lean Manufacturing. Podjęto próbę udowodnienia...
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Efektywność dwuetapowego procesu dydaktycznego w publicznych uczelniach technicznych
PublicationCelem niniejszego artykułu jest oszacowanie efektywności dwóch etapów (tj. pierwszy–kształcenia studentów, a drugi–kończenia edukacji przez absolwentów) zachodzących w procesie dydaktycznym w publicznych uczelniach technicznych. Przedstawiono ocenę efektywności działalności dydaktycznej 18 publicznych wyższych szkół technicznych w latach 2014–2015 za pomocą metody DEA. W badaniu wykorzystano model relacyjny DEA, zakładający...
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Wykorzystanie sieciowego modelu DEA do pomiaru efektywności wydziałów Politechniki Warszawskiej
PublicationW artykule podjęto temat efektywności publicznych szkół wyższych oraz zaprezentowano wstępne wyniki badania w zakresie efektywności dla 18 wydziałów Politechniki Warszawskiej przeprowadzonego w roku akademickim 2014/2015. W analizie za rezultaty przyjęto: liczbę absolwentów (działalność dydaktyczna), liczbę punktów za publikacje („teoretyczna” działalność naukowa) oraz liczbę projektów realizowanych przez wydziały („praktyczna”...
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Dowodzenie w Policji – koncepcja zmian w zakresie dowodzenia formacją
PublicationThe dynamic development of human civilization at the turn of the 20th and 21st centuries unfortunately generates not only positive developments. So we need to constantly improve crisis management systems. The purpose of the research was to improve the police command system. Primarily, the research was based on the methods of non-standard observation and analysis and logical construction. The article presents the command in the...
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Lower Rim Substituted tert-Butyl Calix[4]arenes (Part IV). Calix[4]arene-Crown Ethers as Ionophores in Plasticized PVC-membrane electrodes.
PublicationPrzedstawiono syntezę i charakterystykę trzech p-tert-butylokaliks[4]aren-koron-4, -5, -6 (związki 2 - 4 o różnej długości łańcucha polyoksaetylenowego łączącego distalne grupy OH). Syntezowane związki wykazują wysoką selektywność na kationy sodu, potasu lub cezu. Badano zależność pomiędzy stereochemiczną strukturą tych ligandów, a wyznaczonymi potencjometrycznie współczynnikami selektywności oraz wyznaczonymi stałymi trwałości...
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System oceny efektywności użytkowania aparatów słuchowych (Hearing aid use effectiveness evaluation system)
PublicationCelem rozprawy jest opracowanie metody oceny efektywności protezowania słuchu przy użyciu aparatów słuchowych, która pozwoli w łatwy sposób poddawać ocenie korzyść z użytkowania protez słuchowych w najbardziej typowych sytuacjach akustycznych. Przedstawiono genezę podjętych badań i na tej podstawie zaproponowano cele i tezy rozprawy doktorskiej. W pracy w pierwszej kolejności zawarto przegląd dotyczący rodzajów ubytku słuchu...
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Can augmented democracy fulfil the ideal of deliberative democracy?
PublicationNew technologies can broaden the scope of human limits. We can fly to the moon thanks to rocket science, we can communicate with each other by mobile phones and WiFi and we can exceed human life with medical equipment like pacemakers. But there are aspects of our life that still are very distrustful of implementing new technology into functioning. An example of such a field of our everyday life is...
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Nutrient loss from three small-size watersheds in the southern Baltic Sea in relation to agricultural practices and policy
PublicationAgriculture is the major contributor of waterborne nutrient fluxes into the Baltic Sea, one of the world’s most eutrophication-sensitive areas. Poland, as a large, densely populated state ohf the Baltic Region, with dominating agricultural land use, largely contributes to riverborne loads of N and P. The aim of our study was to examine the input of nutrients from three small first-order agricultural watersheds (Bladzikowski Stream,...
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Evaluation of Terpene Decomposition in Kaffir Lime Juice during Storage Using Gas Chromatography–Mass Spectrometry and Proton Transfer Reaction–Mass Spectrometry
PublicationKaffir lime juice, often treated as production waste, can be a good source of terpenes. These compounds undergo various decomposition processes under the influence of external factors, especially during transportation and storage. In this paper, it was possible to monitor changes in the terpene profile of kaffir lime juice under different storage conditions, namely, 4 ◦C, 20 ◦C, and 35 ◦C. The identification of key decomposition...
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Dictionnaires bilingues, patrimoine culturel et enseignement du français
PublicationL’enseignement des faits de culture, en particulier des phrasèmes, est considéré comme une urgence pour la formation du citoyen actif, d’où l’importance du recours aux dictionnaires bilingues. Or, si le recours à ces supports est fréquent chez les apprenants, il n’est pas recommandé par les enseignants. Notre objectif est de montrer que le recours aux dictionnaires bilingues doit être dosé et que le mode de consultation de ces...
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4D Reconstruction and Visualisation of Krakow Fortress
PublicationThe specific aim of the European project named "Cultural Heritage Through Time" (CHT2) and reported in this paper is to fully integrate the fourth dimension (4D) into Cultural Heritage studies for analysing structures and landscapes over time. Krakow-the Fortress City (Poland) is the one of four case studies of the CHT2, which are used for the time varying reconstruction, analysis, visualization, and preservation. The goal of...
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Direct human contact with siloxanes (silicones): safety or risk. Part 1: characteristics of siloxanes (silicones
PublicationSiloxanes are commonly known as silicones. They belong to the organosiliconcompounds and are exclusively obtained by synthesis. Their chemical structuredetermines a range of physicochemical properties which were recognized as unique.Due to the susceptibility to chemical modifications, ability to create short, long orcomplex polymer particles, siloxanes found an application in many areas of human life.
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Stimulated by cyclodextrins high yield synthesis of azocrown analogues comprising pyrrole or imidazole residues
PublicationThe influence of cyclodextrins (CDs) on the formation of azocrown ethers comprising pyrrole, imidazole and substituted imidazole has been studied. Pyrrole, imidazole, 2-methyl-, 4-methyl- and 4-phenylimidazole were coupled with bisdiazonium salts derived from bis-1,5-(2-aminophenoxy)-3-oxapentane or bis-1,8-(2-aminophenoxy)-3,6-dioxaoctane to form macrocyclic compounds with two azo units. The syntheses were performed under standard...
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Syntheses of N-Substituted Thymine Thioacetamides. A Novel Approach to Site Selective Acylation of Diaminoalkanes
PublicationA new series of N-substituted thiocarbamoyl derivs. contg. histamine, tryptamine, and other moieties having at least one amino group attached to an aliph. chain has been synthesized from (1-thyminyl)thioacetamide in good isolated yields (69-86%). N-[2-(4-Imidazolyl)ethyl](1-thyminyl)thioacetamide was hydrolyzed to its amide on prolonged heating in water. Ammonium sulfide (20-22% soln. in water) has found interesting new applications...
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100-lecie powstania Zrzeszenia Studentów Polaków Politechniki Gdańskiej. Bratnia Pomoc i Korporacji ZAG Wisła
PublicationW 2021 roku przypada 100-lecie utworzenia Korporacji ZAG Wisła, nawiązującej do tradycji pierwszej polskiej organizacji Związku Akademików Gdańskich, oraz utworzenia i zalegalizowania samopomocowej organizacji zrzeszającej...
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Influence of the addition of citric acid on the physico-chemical properties of poly(sorbitol sebacate-co- butylene sebacate)
PublicationThe article presents the results of the physicochemical properties of poly(sorbitol sebacate- co-butylene sebacate) (PSBS) obtained with 0.25; 0.5; 0.75; 1 mol of citric acid (KC). It was shown that PSBS obtained with 0.25 and 0.5 mol KC is characterized by the most optimal mechanical and thermal properties. As a result of the study, it was found that the use of sorbitol and citric acid allows obtaining ester materials with...
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ZASTOSOWANIE WYŁĄCZNIKA BEZPIECZNIKOWEGO DO FORMOWANIA IMPULSU WIELKIEJ MOCY
PublicationW wielu układach fizycznych i technicznych konieczne jest wytwarzanie impulsów wielkiej mocy o krótkim czasie trwania (rzędu ułamków µs). Impulsy te uzyskuje się stosując układy formujące zasilane ze źródła impulsowego wielkiej mocy, o długim czasie trwania impulsu, rzędu kilkudziesięciu µs. Jednym z układów formujących jest bezpiecznik wyłącznikowy. W pracy metodą symulacyjną badano wpływ parametrów bezpiecznika wyłącznikowego...
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S’attaquer à la suprématie du masculin sur le féminin : le français inclusif dans les publications des universités françaises dans les réseaux sociaux
PublicationThis paper aims to examine the use of inclusive French in the Internet publications of Paris universities on their social media. Three higher education institutions were selected: Paris Dauphine-PSL University, Gustave Eiffel University, and Sorbonne Paris North University. The publications were obtained from Facebook, Instagram, and LinkedIn. Firstly, the groups of people to whom the use of inclusive French referred...
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Hetero-junction composed of poly(3,4-ethylenedioxythiophene) with poly(styrenesulphonate) and iodine doped titanium dioxide
PublicationPraca prezentuje nowe objętościowe heterozłacze typu p-n, gdzie domieszkowany jodem ditlenek tytanu (I-TiO2) pełni rolę elementu n, a poli(3,4-etylenodioksytiofen):poli(etylenosulfonian)(pEDOT:PSS)rolę elementu p. Heterozłącze zostało otrzymane na drodze potencjostatycznej polimeryzacji monomeru w obecnosci nanoproszku I-TiO2 zawieszonego w elektrolicie. Metoda pozwala na otrzymanie warstw hybrydowych, gdzie cząstki I-TiO2 są wbudowane...
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Better polynomial algorithms for scheduling unit-length jobs with bipartite incompatibility graphs on uniform machines
PublicationThe goal of this paper is to explore and to provide tools for the investigation of the problems of unit-length scheduling of incompatible jobs on uniform machines. We present two new algorithms that are a significant improvement over the known algorithms. The first one is Algorithm 2 which is 2-approximate for the problem Qm|p j = 1, G = bisubquartic|Cmax . The second one is Algorithm 3 which is 4-approximate for the problem Qm|p...
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The transfer of names in various translations of brothers Grimm’s "Rumpelstilzchen"
PublicationVarious scholars point out the transfer of proper nouns as a difficulty. This paper examines the transfer of names in twenty‑one translations of the Grimm Brothers’ fairy tale originally titled Rumpelstilzchen. The article analyses English,Brazilian Portuguese, Polish, Turkish, and Japanese editions of this originally German story. The analysis focuses on the true name of a title dwarf and other names provided by the Queen....
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A Comprehensive Framework for Measuring Governments’ Digital Initiatives Including Open Data
PublicationDigital innovation and digital initiatives are generally recognized and considered to be the driving forces behind firm survival and success in the market. This is not the case in the public sector, where digital initiatives have suffered not only from a lack of research trying to explain them but also from a major lack of recognition of their importance. The government’s eagerness to introduce more digital initiatives for better...
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Identification of Shift in Sowing and Harvesting Dates of Rice Crop (L. Oryza sativa) through Remote Sensing Techniques: A Case Study of Larkana District
PublicationThe present study aimed to determine the impact of climate variability on rice crops in terms of sowing and harvesting dates and crop period. The identification of sowing and harvesting dates were spotted by mask identification, variations in land surface temperature (LST) on a temporal scale in the respective months, and a field-level social inquiry. The study was conducted during a time period (1994–2017), in which geo-referenced...
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A pilot study with flow mediated skin fluorescence: A novel device to assess microvascular endothelial function in coronary artery disease
PublicationBackground: Endothelial dysfunction is one of the earliest vascular manifestations in the pathogenesis of cardiovascular disease. Noninvasive, simple and inexpensive methods of endothelial function assessment are therefore needed. Methods: Microvascular endothelial function was assessed in coronary artery disease (CAD) patients by flow mediated skin fluorescence (FMSF), based on measurements of NADH fluorescence intensity during...
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Adipokine and cytokine levels in patients with adrenocortical cancer, subclinical Cushing's syndrome and healthy controls
PublicationIntroduction In recent years researchers have focused at hormonal activity in Cushing’s syndrome (CS) in connection with metabolic disorders and the role of adipokines and cytokines secreted by the adipose tissue. The aim of the study was to investigate levels of adipokines and cytokines in patients with: subclinical CS (SCS) – in relation to hormonal parameters of hypercortisolemia, and, adrenocortical cancer (ACC). Materials...
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublicationBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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Unusual cis-diprotonated forms and fluorescent aggregates of non-peripherally alkoxy-substituted metallophthalocyanines
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Glycerol extracts of Glycyrrhiza glabra, Echinacea purpurea, Silybum marianum and Berberis vulgaris: chemical characterisation and cosmeceutical potential
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Study on physical and technological effects of precise turning with self-propelled rotary tool
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Sleep assessment in obsessive-compulsive disorder treated with deep brain stimulation - double case report of morning and evening chronotype patients
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Enhanced supercapacitor materials from pyrolyzed algae and graphene composites
PublicationThis study focuses on the synthesis and characterization of supercapacitor materials derived from pyrolyzed natural compounds. Four compounds were investigated: methylcellulose with lysine (ML), methylcellulose with lysine-graphene composite (MLG), algae (A), and algae-graphene composite (AG). The pyrolysis process was utilized to convert these natural compounds into carbon-based materials suitable for supercapacitor applications....
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Recent advancements in LC‐MS based analysis of biotoxins: Present and future challenges
PublicationThere has been a rising concern regarding the harmful impact of biotoxins, source of origin, and the determination of the specific type of toxin. With numerous reports on their extensive spread, biotoxins pose a critical challenge to figure out their parent groups, metabolites, and concentration. In that aspect, liquid chromatography‐mass spectrometry (LC‐MS) based analysis paves the way for its accurate identification and quantification....
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Development and application of asphalt binder relaxation test in different dynamic shear rheometers
PublicationIn this study, a novel relaxation test is proposed to evaluate asphalt binder low temperature properties using a Dynamic Shear Rheometer (DSR) with parallel plates of 4 mm in diameter. Three rheometers from three different manufacturers are used to analyze seven asphalt binders. Different material parameters are derived which are useful to evaluate and discriminate different asphalt binders. Test results of all three instruments...
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Activated sodium percarbonate-ozone (SPC/O3) hybrid hydrodynamic cavitation system for advanced oxidation processes (AOPs) of 1,4-dioxane in water
PublicationHydrodynamic cavitation (HC) was employed to activate sodium percarbonate (SPC) and ozone (O3) to degrade recalcitrant 1,4-dioxane. The degradation efficiency > 99 % with a rate constant of 4.04 × 10−2 min−1 was achieved in 120 min under the optimal conditions of cavitation number (Cv) 0.27, pH 5, molar ratio of oxidant to pollutant (rox) 8, ozone dose of 0.86 g h−1 under 25 ± 2 °C with initial concentration of 1,4-dioxane 100...