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Search results for: AMFOTERYCYNA-B
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Competition adsorption of malachite green and rhodamine B on polyethylene and polyvinyl chloride microplastics in aqueous environment
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Persulfates to degrade a mixture of dyes (rhodamine B, methylene blue) in the presence of glucose and visible light
PublicationA treatment process utilizing visible-light-activated (Vis) persulfates (PS) in the presence of an organic promoter (glucose) was developed for the simultaneous decolorization of a rhodamine B (RhB) and methylene blue (MB) mixture. Various doses of glucose, PS concentrations, pH values, initial dye concentrations and process time were tested to find out the most appropriate parameters for degrading the RhB/MB mixture in the...
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Krytyczny stosunek ciśnień b w rozumieniu norm ISO 6358 i ISO 6953
PublicationJednym z parametrów służących do opisu właściwości przepływowych elementu pneumatycznego jest krytyczny stosunek ciśnień b, zdefiniowany i wykorzystywany w ISO 6358 oraz ISO 6953. Jednak w myśl metod jego wyznaczania opisanych w ISO 6358 i ISO/DIS 6358 definicja ta wydaje się być inna. W pracy omówiono warunki jakie musi spełniać element pneumatyczny, aby wartość b wyznaczona tymi metodami była zbliżona do wartości definicyjnej....
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Testbed analysis of video and VoIP transsmission performance in IEEE 802.11 b/g/n networks
PublicationThe aim of the work is to analyze capabilities and limitations of different implementations of IEEE 802.11 technologies (IEEE 802.11 b/g/n), utilized for both video streaming and VoIP calls directed to mobile devices. Our preliminary research showed that results obtained with currently popular simulation tools can be drastically different than these possible in real-world environment, so, in order to correctly evaluate performance...
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Internacjonalizacja działalności badawczo-rozwojowej (B+R) przedsiębiorstw high-tech. Wyniki badań empirycznych
PublicationGłownym celem artykułu jest przedstawienie roli badań i rozwoaju (B+R) w procesie internacjonalizacji przedsiębiorstw high-tech. Artykuł obejmuje przegląd literatury oraz wyniki badań 263 przedsiębiorstw high-tech przeprowadzonych na terytorium Polski. Artykuł powstał w ramach projektu badawczego OPUS 6 pt. Wzorce internacjonalizacji małych i średnich przedsiębiorstw działających w branżach high-tech finansowanego przez Narodowe...
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Interactions of amphotericin B derivative of low toxicity with biological membrane components - the Langmuir monolayer approach
PublicationMetodą monowarstw Langmuira zbadano naturę oddziaływań nowej pochodnej antybiotyku przeciwgrzybowego amfoterycyny B o niskiej toksyczności, tj. estru metylowego N-metylo-N-D-fruktopiranozyloamfoterycyny B (MF-AME)z komponentami błon biologicznych: ergosterolem, występującym w komórkach grzybowych i cholesterolem występującym w komórkach zwierzęcych oraz z modelowym fosfolipidem DPPC i na tej podstawie stwierdzono, że zróżnicowanie...
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MEMORY EFFECT ANALYSIS USING PIECEWISE CUBIC B-SPLINE OF TIME FRACTIONAL DIFFUSION EQUATION
PublicationThe purpose of this work is to study the memory effect analysis of Caputo–Fabrizio time fractional diffusion equation by means of cubic B-spline functions. The Caputo–Fabrizio interpretation of fractional derivative involves a non-singular kernel that permits to describe some class of material heterogeneities and the effect of memory more effectively. The proposed numerical technique relies on finite difference approach and cubic...
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Antibiotic-sterol interactions provide insight into the selectivity of natural aromatic analogues of amphotericin B and their photoisomers
PublicationAromatic heptaene macrolides (AHMs) belong to the group of polyene macrolide antifungal antibiotics. Members of this group were the first to be used in the treatment of systemic fungal infections. Amphotericin B (AmB), a non-aromatic representative of heptaene macrolides, is of significant clinical importance in the treatment of internal mycoses. It includes the all-trans heptaene chromophore, whereas the native AHMs contain two...
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Sequence-dependent structural properties of B-DNA: what have we learned in 40 years?
PublicationThe structure of B-DNA, the physiological form of the DNA molecule, has been a central topic in biology, chemistry and physics. Far from uniform and rigid, the double helix was revealed as a flexible and structurally polymorphic molecule. Conformational changes that lead to local and global changes in the helix geometry are mediated by a complex choreography of base and backbone rearrangements affecting the ability of the B-DNA...
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Self-assembly, stability and conductance of amphotericin B channels: bridging the gap between structure and function
PublicationAmphotericin B (AmB), one of the most powerful but also toxic drugs used to treat systemic mycoses, is believed to selectively permeabilize fungal cell membranes to ions in a sterol-dependent manner. Unfortunately, the structure of the biologically active AmB channels has long eluded researchers, obstructing the design of safer alternatives. Here, we investigate the structural and thermodynamic aspects of channel formation, stability,...
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Deep eutectic solvents in analytical sample preconcentration Part B: Solid-phase (micro)extraction
PublicationOne of the key challenges of modern analytical chemistry is the monitoring of trace amounts of contaminants using sensitive and selective instrumental techniques. Due to the variety and complexity of some samples, it is often necessary to properly prepare a sample and to perform a preconcentration of trace amounts of analytes. In line with the principles of Green Analytical Chemistry (GAC), it is important for an analytical procedure...
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Charge-based deep level transient spectroscopy of B-doped and undoped polycrystalline diamond films
PublicationThe undoped and B-doped polycrystalline diamond thin film was synthesized by hot filament chemical vapor deposition and microwave plasma, respectively. The structural characterization was performed by scanning electron microscopy, X-ray diffraction and Raman spectroscopy. The electrical properties of synthesized diamond layer were characterized by dc-conductivity method and charge deep level transient spectroscopy. The B-doped...
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Numerical simulation of the influence of the selected factors on the performance of a concrete road barrier H2/W5/B
PublicationThis paper discuss the influence of selected factors on the performance of a concrete road barrier H2/W5/B. Modelling techniques of a concrete road safety system were briefly discussed. Comparison to the full scale crash test results has been shown. The concrete road safety barrier has been investigated for evaluation of the overall damage after collision under various initial conditions. The failure assessment criterion has been...
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Photocatalytic decolourization of Rhodamine-B dye by visible light active ZIF-8/BiFeO3 composite
PublicationIn this work, preparation of ZIF-8 supported BiFeO3 photocatalyst by ultrasound cavitation technique was reported. The synthesized materials were characterized using solid UV absorption spectroscopy, Raman Spectroscopy, and SEM. The catalytic function of synthesized photocatalyst under ultraviolet and visible light was examined for the decolourization of Rhodamine-B (Rh-B) dye. To understand the action of the photocatalyst on Rh-B...
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Charakterystyka mechanizmów samoorganizującej się, wieloskokowej sieci bezprzewodowej w strefie B systemu netBaltic
PublicationStrefowa struktura systemu netBaltic pozwala na zastosowanie w jego obrębie odmiennych mechanizmów komunikacji sieciowej w zależności od dostępnych w określonym momencie dla danej jednostki możliwości komunikacyjnych. W strefie B systemu przewidziano wykorzystanie samoorganizującej, wieloskokowej sieci o strukturze kratowej, pozwalającej znacząco rozszerzyć zasięg łączności sieciowej poza obszar funkcjonowania lądowych systemów...
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Self-Association of Amphotericin B: Spontaneous Formation of Molecular Structures Responsible for the Toxic Side Effects of the Antibiotic
PublicationAmphotericin B (AmB) is a lifesaving antibiotic used to treat deep-seated mycotic infections. Both the pharmaceutical activity and highly toxic side effects of the drug rely on its interaction with biomembranes, which is governed by the molecular organization of AmB. In the present work we present detailed analysis of self-assembly of AmB molecules in different environments, interesting from the physiological standpoint, based...
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Membrane Sterols Modulate the Binding Mode of Amphotericin B without Affecting Its Affinity for a Lipid Bilayer
PublicationMembrane-active antibiotics are known to selectively target certain pathogens based on cell membrane properties, such as fluidity, lipid ordering, and phase behavior. These are in turn modulated by the composition of a lipid bilayer and in particular by the presence and type of membrane sterols. Amphotericin B (AmB), the golden standard of antifungal treatment, exhibits higher activity toward ergosterol-rich fungal membranes, which...
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Primary mediastinal B-cell lymphoma – metabolic and anatomical features in 18FDG-PET/CT and response to therapy
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A study on the interaction of rhodamine B with methylthioadenosine phosphorylase protein sourced from an Antarctic soil metagenomic library.
PublicationThe presented study examines the phenomenon of the fluorescence under UV light excitation (312 nm) of E. coli cells expressing a novel metagenomic-derived putative methylthioadenosine phosphorylase gene, called rsfp, grown on LB agar supplemented with a fluorescent dye rhodamine B. For this purpose, an rsfp gene was cloned and expressed in an LMG194 E. coli strain using an arabinose promoter. The resulting RSFP protein was purified...
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The extracellular loop of Man-PTS subunit IID is responsible for the sensitivity of Lactococcus garvieae to garvicins A, B and C
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Measurements of OF QoS/QoE parameters for media streaming in a PMIPv6 TESTBED WITH 802.11 b/g/n WLANs
PublicationA growing number of mobile devices and the increasing popularity of multimedia services result in a new challenge of providing mobility in access networks. The paper describes experimental research on media (audio and video) streaming in a mobile IEEE 802.11 b/g/n environment realizing network-based mobility. It is an approach to mobility that requires little or no modification of the mobile terminal. Assessment of relevant parameters...
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Hepatitis D, B and C virus (HDV/HBV/HCV) coinfection as a diagnostic problem and therapeutic challenge
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Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes
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Improved mechanical properties of W-Zr-B coatings deposited by hybrid RF magnetron – PLD method
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Base-Catalyzed, Solvent-Free Synthesis of Rigid V-Shaped Epoxydibenzo[b,f][1,5]diazocines
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Zastosowanie algorytmów genetycznych do projektowania ram stalowych zgodnie z PN-90/B-03200.
PublicationW artykule przedstawiono optymalizacje ramy przy wykorzystaniu w obliczeniach zapasu nosnosci wynikajacego z dopuszczenia pracy scianek skladajacych sie na profil w stanie nadkrytycznym ograniczonym.Optymalizacje przeprowadzono wykorzystujac metode oparta na algorytmach genetycznych.Wyniki optymalizacji dla stanu krytycznego i nadkrytycznego ograniczonego zestawiono ze soba i porownano.
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Parameter of nonlinearity B/A of three-component systems with separate volumes of liquid, its vapor and a neutral gas
PublicationOtrzymane zostało wyrażenie dla zaburzenia entropii substancji o trzech komponentach jako funkcja zaburzeń jej ciśnienia i gęstości. Na podstawie wzoru prędkość i parametru nieliniowosci fali akustycznej zostały wyliczone jako funkcje i ciśnienia i koncentracji pary i powietrza. Rezultaty są przedstawione w postaci wykresów.
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Analiza redystrybucji środków finansowych przeznaczonych na działalność B+R (na przykładzie wybranej uczelni)
PublicationAutor zwraca uwagę na wyjątkowo niskie finansowanie działalności B+R w Polsce na tle innych krajów nowo przyjętych do UE. Przeprowadza analizę redystrybucji tych skromnych środków w skali Polski oraz na przykładzie konkretnej uczelni. Dostrzega dwa charakterystyczne zjawiska, określona jako asymetrie. Pierwsze-dotyczące podziału tych środków między szkoły wyższe, jednostki badawczo-rozwojowe i placówki PAN. Drugie - dotyczące struktury...
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Immune escape of B-cell lymphoblastic leukemic cells through a lineage switch to acute myeloid leukemia
PublicationAcute leukemia (AL) with a lineage switch (LS) is associated with poor prognosis. The predisposing factors of LS are unknown, apart from KMT2A rearrangements that have been reported to be associated with LS. Herein, we present two cases and review all 104 published cases to identify risk factors for LS. Most of the patients (75.5%) experienced a switch from the lymphoid phenotype to the myeloid phenotype. Eighteen patients (17.0%)...
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Le reti della terza Italia.Imprese, calcio, sponsirzzazioni e territorio in Serie B 81982-2006)
PublicationIl capitolo si occupa dei rapporti tra imprese e sponsirzzazioni dei club calcistici italiani della serie B tra il 1982 e il 2006
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Influence of B/N co-doping on electrical and photoluminescence properties of CVD grown homoepitaxial diamond films
PublicationBoron doped diamond (BDD) has great potential in electrical, and electrochemical sensing applications. The growth parameters, substrates, and synthesis method play a vital role in the preparation of semiconducting BDD to metallic BDD. Doping of other elements along with boron (B) into diamond demonstrated improved efficacy of B doping and exceptional properties. In the present study, B and nitrogen (N) co-doped diamond has been...
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Tailoring Defects in B, N-Codoped Carbon Nanowalls for Direct Electrochemical Oxidation of Glyphosate and its Metabolites
PublicationTailoring the defects in graphene and its related carbon allotropes has great potential to exploit their enhanced electrochemical properties for energy applications, environmental remediation, and sensing. Vertical graphene, also known as carbon nanowalls (CNWs), exhibits a large surface area, enhanced charge transfer capability, and high defect density, making it suitable for a wide range of emerging applications. However, precise...
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Nowa metoda wymiarowania żelbetowych słupów uzwojonych w ujęciu nowelizowanej normy PN-B-03264.
PublicationW artykule przedstawiono nową metodę wymiarowania słupów uzwojonych w ujęciu nowelizowanej normy PN-B-03264. Podano przyczyny wprowadzenia opisywanych w artykule zmian i przedstawiono wcześniejsze próby modyfikacji sposobu obliczania nośności słupów uzwojonych w ujęciu normowym. Przeprowadzono dyskusję wyników obliczeń uzyskiwanych za pomocą nowej metody na tle wyników uzyskiwanych za pomocą dotychczasowej metody normowej, oraz...
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Thermodynamic Cycle Concepts for High-Efficiency Power Plants. Part B: Prosumer and Distributed Power Industry
PublicationAn analysis was carried out for different thermodynamic cycles of power plants with air turbines. A new modification of a gas turbine cycle with the combustion chamber at the turbine outlet has been described in the paper. A special air by-pass system of the combustor was applied, and in this way, the efficiency of the turbine cycle was increased by a few points. The proposed cycle equipped with an effective heat exchanger could...
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Modeling, simulation, and validation of a TB41 crash test of the H2/W5/B concrete vehicle restraint system
PublicationThe paper addresses numerical simulations of a concrete vehicle restraint system. The model is described in detail. The advanced material law of the continuous surface cap model was used to analyze the damage locations in concrete barrier segments. The results were validated against the TB41 full-scale crash test. The test was conducted in compliance with European standard EN 1317, and the validation was performed in accordance...
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Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
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Sol–gel glasses with enhanced luminescence of laser dye Rhodamine B due to plasmonic coupling by copper nanoparticles
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Experimental ORC micro-power plant for CHP application Part B: Radial and Multi-stage axial turbines
PublicationThe co-generative micro-power plant with the HFE7100 applied as a working medium was designed and built for experimental investigations. Special attention is paid to a micro-turbine which was built and tested in two variants: a radial turbine and an axial turbine. A concept of a radial turbine with 2 centripetal and 2 centrifugal stages is shown. This prototype was equipped with an aerostatic gas bearing and, alternatively, with...
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Investigation of changes in the type B PLC effect of Al–Mg–Cu type alloy for various strain rates
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On the Possibility of the Amphotericin B-Sterol Complex Formation in Cholesterol- and Ergosterol-Containing Lipid Bilayers: A Molecular Dynamics Study
PublicationAmphotericin B (AmB) is a well-known membrane-active antibiotic that has been used to treat systemicfungal infections for more than 45 years. Therapeutic application of AmB is based on the fact that it is moreactive against ergosterol-containing membranes of fungal cells than against mammalian membranes withcholesterol. In this paper, we examine the hypothesis according to which the selectivity of the AmB's membraneaction originates...
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Amperometryczne czujniki ditlenku siarki oraz polimerowe czujniki wilgotności. właściwości prototypów własnej konstrukcji / B. Chachulski.
PublicationW pracy przedstawiono aktualny stan wiedzy obejmujący podstawy teoretyczne mechanizmu działania amperometrycznych czujników gazowych zanieczyszczeń atmosfery z ciekłym elektrolitem. Opisano większość opublikowanych dotąd rozwiązań konstrukcyjnych takich czujników wraz z ich właściwościami metrologicznymi. Zamieszczono dane dotyczące materiałów elektrodowych stosowanych w czujnikach z elektrodami metalowymi oraz z elektrodami gazodyfuzyjnymi,...
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Molecular organization of antifungal antibiotic amphotericin B in lipid monolayers studied by means of Fluorescence Lifetime Imaging Microscopy
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Characterisation of adenovirus strains represented species B and E isolated from broiler chicken flocks in eastern Poland
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Mechanical and Thermal Properties of W-Ta-B Coatings Deposited by High-Power Impulse Magnetron Sputtering (HiPIMS)
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Epoxydibenzo[b,f][1,5]diazocines: From a Hidden Structural Motif to an Efficient Solvent-Free Synthetic Protocol
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The existence and stability of the anions matching the formula (M=Li, Na, K, Be, Mg, Ca, B, Al, Ga)
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Investigation of changes in the type B PLC effect of Al-Mg-Cu type alloy for various strain rates
PublicationEfekt Portevina-LeChateliera ujawnia się w postaci skokowych zmian naprężenia w trakcie procesu odkształcenia próbek pewnych stopów. Zjawisko PLC występuje w kilku odmianach charakteryzujących się istotnymi różnicami zarówno w przestrzennym rozkładzie pasm odkształcenia jak też przebiegu krzywej naprężeniowej. Przebiegi odpowiadające różnym odmianom serration charakteryzują się odmiennymi właściwościami rozkładu energetycznego...
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Rozstaw rys według PN-EN 1992-1-1:2008 oraz PN-B 03264:2002
PublicationW pracy opisano mechanizm powstawania rys dla osiowo rozciąganego pręta żelbetowego. Na tej podstawie określono maksymalny i minimalny rozstaw rys, konfrontując otrzymane wyniki z procedurami podanymi w normie europejskiej PN-EN 1992-1-1:2008 oraz w normie polskiej PN-B 03264:2002. Przedstawiono praktyczne wnioski do projektowania, wynikajace z przeprowadzonej analizy.
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Application of Micro-cloud point extraction for spectrophotometric determination of Malachite green, Crystal violet and Rhodamine B in aqueous samples
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B-GALACTOSIDASE ARTHROBACTER SP. 32cB - OBTAINING THE GENE SEQUENCE, CONSTRUCTION OF THE EXPRESSION SYSTEM, BIOSYNTHESIS AND BIOCHEMICAL CHARACTERIZATION OF THE ENZYME
PublicationINTRODUCTION: β-Galactosidase is an enzyme which catalyzes the hydrolysis of O glycosidic bond in β-galactosides. Another activity of β galactosidase is a transglycosylation activity. The main industrial use of this protein is the hydrolysis of lactose in milk in a cooling conditions. Synthesis of galactooligosaccharides, which are mostly used as a prebiotics added to some foods or available as dietary supplements, is only one...