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Low-cost data-driven modelling of microwave components using domain confinement and PCA-based dimensionality reduction
PublicationFast data-driven surrogate models can be employed as replacements of computationally demanding full-wave electromagnetic simulations to facilitate the microwave design procedures. Unfortunately, practical application of surrogate modelling is often hindered by the curse of dimensionality and/or considerable nonlinearity of the component characteristics. This paper proposes a simple yet reliable approach to cost-efficient modelling...
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Bezpieczeństwo poufności i integralności danych w Radiowym Systemie Monitorowania i Akwizycji Danych z Urządzeń Fotoradarowych (RSMAD)
PublicationW referacie przedstawiono koncepcję rozwiązań bezpieczeństwa kryptograficznego w Radiowym Systemie Monitorowania i Akwizycji Danych z Urządzeń Fotoradarowych (RSMAD). Opisano budowę wykorzystanego algorytmu kryptograficznego AES oraz trybu CBC, w jakim ma pracować ten algorytm w systemie RSMAD. Zaprezentowano również zastosowaną metodę uwierzytelnienia i kontroli integralności przesyłanych w systemie danych wykorzystującą funkcje...
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Requirements for Residual Current Devices Intended for Electric Vehicle Charging Systems
PublicationThe properties of residual current devices have been presented from the point of view of their ability to detect a specific shape of the residual current waveform. Moreover, the standard requirements relating to residual current protection used in electric vehicle charging installations have been pointed out. The operating characteristics of the IC-CPD and RDC-DD protections, which are intended for charging electric vehicles in...
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Multichannel Human Body Communication
PublicationHuman Body Communication is an attractive alternative for traditional wireless communication (Bluetooth, ZigBee) in case of Body Sensor Networks. Low power, high data rates and data security makes it ideal solution for medical applications. In this paper, signal attenuation for different frequencies, using FR4 electrodes, has been investigated. Performance of single and multichannel transmission with frequency modulation of analog...
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Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2
PublicationW pracy zidentyfikowaliśmy elementy struktury chemicznej dla 23 pochodnych imidazoakrydonu odpowiedzialne za ich rozpoznawanie przez transporter typu ABC, białko ABCG2. za transport tych związków przez pompę ABCG2 odpowiedzialne jest grupa hydroksylowa w pozycjach R1, R2 i R3 chromoforu. Stwierdziliśmy także, że zwiększanie ilości grup metylenowych łańcucha bocznego imidazoakrydonów powodowało zmniejszenie aktywnego transportu...
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ANALYSIS OF IMPACT of SHIP model parameters on changes of control quality index in ship dynamic positioning system
PublicationIn this work there is presented an analysis of impact of ship model parameters on changes of control quality index in a ship dynamic positioning system designed with the use of a backstepping adaptive controller. Assessment of the impact of ship model parameters was performed on the basis of Pareto-Lorentz curves and ABC method in order to determine sets of the parameters which have either crucial, moderate or low impact on objective...
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Electronic States of Tris(bipyridine) Ruthenium(II) Complexes in Neat Solid Films Investigated by Electroabsorption Spectroscopy
PublicationWe present the electric field-induced absorption (electroabsorption, EA) spectra of the solid neat films of tris(bipyridine) Ru(II) complexes, which were recently functionalized in our group as photosensitizers in dye-sensitized solar cells, and we compare them with the results obtained for an archetypal [Ru(bpy)3]2+ ion (RBY). We argue that it is difficult to establish a unique set of molecular parameter values by discrete parametrization...
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Post-match recovery profile of leukocyte cell subsets among professional soccer players
PublicationThis study assessed the impact of cumulative match time on the distribution of CD45+ cell subtests in the capillary blood of professional soccer players. Twenty-two males (aged 18–30 years) took part in the 36-week study. Participants playing up to 540 in cumulative match time and less than 30 min in each single match during the observation period formed the control group. White blood cell (WBC) phenotyping and creatine kinase...
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Optimal backbone coloring of split graphs with matching backbones
PublicationFor a graph G with a given subgraph H, the backbone coloring is defined as the mapping c: V(G) -> N+ such that |c(u)-c(v)| >= 2 for each edge uv \in E(H) and |c(u)-c(v)| >= 1 for each edge uv \in E(G). The backbone chromatic number BBC(G;H) is the smallest integer k such that there exists a backbone coloring with max c(V(G)) = k. In this paper, we present the algorithm for the backbone coloring of split graphs with matching backbone.
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Kontekstowo zorientowany model bezpieczeństwa systemów internetowych
PublicationW rozprawie dokonano analizy usługowych systemów internetowych pod względem bezpieczeństwa. Przedstawiono autorskie uniwersalne modele bezpieczeństwa CoRBAC oraz jego rozszerzenie TCoRBAC, będące rozwinięciem tradycyjnego modelu RBAC. Uwzględniono analizę szeroko rozumianego kontekstu funkcjonowania systemu oraz poziom jego zaufania do użytkownika. Opracowano metodę wyznaczania dwóch parametrów: zaufania do systemu (λ) będącego...
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Amphotericin B derivatives: novel strategy for the development of non-toxic, broad spectrum, fungicidal and overcoming multidrug resistance antifungal agents.
PublicationZaprezentowano porównawczą charakterystykę działania amfoterycyny B (AmB) oraz jej pochodnych o różnym stopniu selektywnej toksyczności na szczepy grzybów reperezentujących różne mechanizmy oporności. Były to mutanty C. albicans posiadające defekt w szlaku biosyntezy ergosterolu oraz wielolekooporne szczepy S. cerevisiae wyposażone w pompy eksportujące typu ABC i MFS. Badania obejmowały: 1)porównanie aktywności przeciwgrzybowej...
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Influence of stirrups in a concrete shell on strengthening reinforced concrete column
PublicationTwelve concrete columns, with a 150x150mm square section and three columns with a circular section (d=200mm), are tested to investigate the effect of strengthening by RC jacket. Based on a confined concrete model for axial static loading, an analytical methods, reported in the literature are proposed to predict the behavior of columns with RC jacket. The results support the conception that the effect of strengthening depends...
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An examination of an Antarctic soil metagenomic-derivate putative methylthioadenosine phosphorylase gene as a novel reporter gene for promoter trapping
PublicationThe rsfp gene was discovered during examination ofan Antarctic soil-derived metagenome library and encodesa bacterial methylthioadenosine phosphorylase (GenBank accession number GQ202582). In a previous study, we found that E. coli colonies expressing the rsfp gene reveal strong pink fluorescence after exposure to UV light when grown on culture medium supplemented with rhodamine B (Cieśliński et al., 2009). In contrast to that,...
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A Goal-Oriented Error Estimator for Reduced Basis Method Modeling of Microwave Devices
PublicationThis letter proposes a novel a-posteriori error estimator suitable for the reduced order modeling of microwave circuits. Unlike the existing error estimators based on impedance function residuals, the new one exploits the residual error associated with the computation of the scattering matrix. The estimator can be effectively used in the Reduced Basis Method (RBM) to automatically generate reduced-order models. The results of numerical...
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Przegląd systemów ładowania elektrycznych osobowych pojazdów i koncepcja dwukierunkowej ładowarki pokładowej
PublicationAktualnie trwa intensywny rozwój pojazdów elektrycznych (EV) i hybrydowych typu plug-in (PHEV) z pokładowymi bateriami akumulatorów. Badania w tej dziedzinie skupiają się na maksymalizowaniu sprawności oraz minimalizowaniu masy i objętości systemów ładowania baterii. W artykule przedstawiono podział systemów ładowania osobowych pojazdów typu EV/PHEV. Opisano systemy ładowania przewodowego z podziałem na ładowarki pokładowe i zewnętrzne, systemy...
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Bezpieczeństwo sieci szkieletowej All-IP w systemie komórkowym UMTS
PublicationW pracy przedstawiono podstawowe mechanizmy zabezpieczeń funkcjonujące w sieci szkieletowej systemu UMTS, ze szczególnym uwzględnieniem protokołu IPsec. Badania i analizy zostały przeprowadzone w głównej mierze w oparciu o dokumenty standaryzacyjne systemu UMTS oraz zalecenia RFC organizacji IETF. Niniejsza praca powstała głównie z myślą o operatorach telefonii komórkowej trzeciej generacji. Aspiracją autora, towarzyszącą powstaniu...
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Pomorska Biblioteka Cyfrowa jako cyfrowe repozytorium dorobku cywilizacyjnego regionu
PublicationW pracy przedstawiono główne założenia i cele projektu Pomorskiej Biblioteki Cyfrowej(PBC), partnerów biorących udział w jego realizacji, a także spodziewany wpływ na szeroko rozumiany rozwój społeczeństwa regionu i Polski. Celem opisywanego projektu jest stworzenie ogólnodostępnej biblioteki cyfrowej, która umożliwi zachowanie i prezentację w Internecie szerokiemu gronu odbiorców zabytków piśmienniczych i niepiśmienniczych znajdujących...
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Crystal structures of eight- and ten-membered cyclic bisanisylphosphonothioyl disulfanes and comparison with their P-ferrocenyl analogues
PublicationTwo new crystal structures of eight- and ten-membered cyclic bisanisylphosphonothioyl disulfanes, namely 2,5-bis(4-methoxyphenyl)-1,6,3,4,25,55- dioxadithiadiphosphocane-2,5-dithione, C16H18O4P2S4, and 2,5-bis(4-methoxyphenyl)-1,6,3,4,25,55-dioxadithiadiphosphecane-2,5-dithione, C18H22O4P2S4, have been determined and compared to structures of the ferrocenyl analogues. The eight-membered rings have similar conformations (TBC) but...
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Positron binding to alkali-metal hydrides: The role of molecular vibrations
PublicationThe bound vibrational levels for J=0 have been computed for the series of alkali-metal hydride molecules from LiH to RbH, including NaH and KH. For all four molecules the corresponding potential-energy curves have been obtained for each isolated species and for its positron-bound complex (e+XH). It is found that the calculated positron affinity values strongly depend on the molecular vibrational state for which they are obtained...
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The role of glucuronidation in drug resistance
PublicationThe final therapeutic effect of a drug candidate, which is directed to a specific molecular target strongly depends on its absorption, distribution, metabolism and excretion (ADME). The disruption of at least one element of ADME may result in serious drug resistance. In this work we described the role of one element of this resistance: phase II metabolism with UDP-glucuronosyltransferases (UGTs). UGT function is the transformation...
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Attention-Based Deep Learning System for Classification of Breast Lesions—Multimodal, Weakly Supervised Approach
PublicationBreast cancer is the most frequent female cancer, with a considerable disease burden and high mortality. Early diagnosis with screening mammography might be facilitated by automated systems supported by deep learning artificial intelligence. We propose a model based on a weakly supervised Clustering-constrained Attention Multiple Instance Learning (CLAM) classifier able to train under data scarcity effectively. We used a private...
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Koncepcja badań nad wielopłaszczyznową analizą współpracy uczelnie-biznes w Polsce
PublicationArtykuł porusza kwestie związane z określeniem i badaniem wielopłaszczyznowej współpracy uczelni z biznesem (UBC – University Business Cooperation) w Polsce. Prezentowane w literaturze modele współpracy nie przedstawiają zależności między poszczególnymi płaszczyznami współpracy, a jedynie je przywołują. Analiza wybranych czynników sukcesu współpracy, wzrostu efektywności i przedsiębiorczości akademickiej, dysfunkcji współpracy...
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Evaluating the Cost of Personnel Activities in Cybersecurity Management: A Case Study
PublicationThe methods of cybersecurity costs' evaluation are inclined towards the cost of incidents or technological acquirements. At the same time, there are other, less visible costs related to cybersecurity that require proper recognition. These costs are associated with the actions and the time spent by employees on activities connected to cybersecurity management. The costs form a considerable component of cybersecurity expenditures,...
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Dynamically positioned ship steering making use of backstepping method and artificial neural networks
PublicationThe article discusses the issue of designing a dynamic ship positioning system making use of the adaptive vectorial backstepping method and RBF type arti cial neural networks. In the article, the backstepping controller is used to determine control laws and neural network weight adaptation laws. e arti cial neural network is applied at each time instant to approximate nonlinear functions containing parametric uncertainties....
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Investigation of interaction between xanthene dye rhodamine B and metagenomic-derivated methylthioadenosine phosphorylase RSFP
PublicationIn the previous study we found that the expression of the metagenomic - derived methylthioadenosine phosphorylase gene (rsfp) in E. coli cells and the presence of rhodamine B in the growth medium were crucial for the pink fluorescence of one E. coli colony from Antarctic soil metagenomic library (Cieśliński et al., 2009). In this study, rsfp gene expression was induced by an arabinose promoter in an LMG194 E. coli strain and the...
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Antioxidant and antimicrobial activity of fermented beverages obtained from fruit pomace
PublicationFruit pomace should not be considered as a waste product but as a by-product as it contains a lot of valuable components such as dietary fiber, bioactive compounds and a source of nutrients. The reasonable way to utilize these by-products, both fresh or dried, could be the fermentation of its extracts, leading to beverages with functional properties. In our research, we checked the possibility of using chokeberry, apple and...
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Experimental investigation of domestic gas boiler fitted with ORC module
PublicationIn the paper the prototype of innovative domestic cogenerative ORC system, consisting of a conventional gas boiler and a small size axial vapour microturbines (in-house designed for ORC and the commercially available for Rankine cycle (RC)), evaporator and condenser were scrutinised. In the course of study the fluid working temperatures, rates of heat, electricity generation and efficiency of the whole system were obtained. The...
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Reminiscencje: 18. Międzynarodowe Seminarium Obróbki Drewna w Vancouver. Obróbka drewna w British Columbia
PublicationPrzedstawiono sprawozdanie ze zwiedzania dwu zakładów produkcyjnych usytuowanych w miejscowosci Delta (BC): Craftsman Wood Products oraz Optimil Machinery. Zwiedzanie było jednym z punktów programu 18 IWMS w Kanadzie.
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Realizacja scalonego filtru kanałowego CMOS do wielosystemowego odbiornika telefonii bezprzewodowej
PublicationW pracy przedstawiono projekt i realizację fizyczną scalonego filtru kanałowego przeznaczonego do wielosystemowego odbiornika telefonii bezprzewodowej. Przedstawiony filtr aktywny wykonano w technice RC w technologii 0,35 um CMOS
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Ograniczenia wirtualnego miernika impedancji opartego na karcie akwizycji danych
PublicationW artykule przedstawiono wirtualny miernik parametrów elementów RLC, zrealizowany w oparciu o komputer PC z zainstalowana kartą akwizycji danych(PCI-6040E) wyposażoną w przetworniki a/c i c/a. Analizowano właściwości metrologiczne miernika zależne od parametrów zastosowanej karty. Przeprowadzono badania symulacyjne błędu pomiaru pojemności uwzględniajace rozdzielczośc i częstotliwośc próbkowania przetwornika a/c oraz jego czas...
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Zarządzanie bezpieczeństwem w złożonych obiektach i instalacjach krytycznych
PublicationW rozdziale scharakteryzowano wybrane metody wspomagające zarządzanie bezpieczeństwem w systemach technicznych, w tym metodę RCM (reliability-centered maintenance) polegającą na proaktywnej obsłudze, której celem jest nie dopuszczać lub przynajmniej ograniczać skutki potencjalnych uszkodzeń oraz metodę RBM (risk-based maintanance) i procedurę RIMAP (risk-based inspection and maintanance procedures) stosowaną w zarządzaniu bezpieczeństwem...
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Phosphate tricyclic coumarin analogs as steroid sulfatase inhibitors: synthesis and biological activity.
PublicationIn the present work, we report convenient methods for the synthesis and biological evaluation of phosphate tricyclic coumarin derivatives as potential steroid sulfatase inhibitors. The described synthesis includes the straightforward preparation of 7-hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one, 3-hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one and 3-hydroxy-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-6-one modified...
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The influence of nanostructures size on V2O5 electrochemical properties as cathode materials for lithium ion battery
PublicationIn this paper, V2O5 nanostructures with a size depending on the annealing temperature are successfully synthesized by a sol-gel method. The crystal structure and morphology of samples are characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), selected area electron diffraction (SEAD) and scanning electron microscopy (SEM), respectively. Electrochemical testing such...
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Titania nanotubes infiltrated with conducting polymer PEDOT modified by Prussian Blue – a novel type of organic-inorganic heterojunction characterised with enhanced photoactivity.
PublicationA highly ordered p–n heterojunction was formed based on titania nanotubes containing a conducting polymer with Prussian blue matrix. The study demonstrates, for the first time, cases when a composite based on titania array scaffolding and Prussian blue embedded in PEDOT exhibits reversible FeII/FeIII redox activity. Highly enhanced photoactivity and capacitance of the obtained material are depicted in comparison to pristine titania....
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Transport properties of microemulsions with ionic liquid apolar domains as a function of ionic liquid content
PublicationThe specific conductivity, dynamic viscosity and apparent diffusion coefficient of each of four aqueous ionic liquid microemulsions (IL-MEs) were measured as a function of ionic liquid (IL) content. The investigated systems were composed of water, hydrophobic ILs (1-butyl-3-methylimidazolium hexafluorophosphate or bis(trifluoromethanesulphonyl)imide) and the nonionic surfactant Triton X-100 or its mixture with cosurfactant (butanol)....
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Synthesis and biological evaluation of novel analogues of batracylin with synthetic amino acids and adenosine: an unexpected effect on centromere segregation in tumor cells through a dual inhibition of topoisomerase IIa and Aurora B
PublicationIn the search for new anticancer agents we designed and synthesized batracylin derivatives with linking synthetic amino acid side chains of different lengths and adenosine. Unexpectedly, we have found that in water and the culture media adenosine–amino acid–BAT conjugates form supramolecular structures and this prevents these compounds from entering cells. Consequently, these compounds exerted no biological activity when tested...
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Silicon oxycarbide ceramics as anodes for lithium ion batteries: influence of carbon content on lithium storage capacity
PublicationWe report here on the synthesis and characterization of silicon oxycarbide (SiOC) in view of its application as a potential anode material for Li-ion batteries. SiOC ceramics are obtained by pyrolysis of various polysiloxanes synthesized by sol–gel methods. The polysiloxanes contain different organic groups attached to silicon, which influence the chemical composition and the microstructure of the final ceramic product. The structure...
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Triple helical collagen-like peptide interactions with selected polyphenolic compounds
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The influence of charge compensation defects on the spectroscopic properties of europium doped Ca9Y(PO4)7
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Influence of Al3+co-doping on the spectral properties of europium doped Ca9Y(PO4)7
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Stabilization of Eu3+ under a reductive atmosphere by the Al3+ co-doping of Sr2SiO4:Eu2+/Eu3+
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Influence of Ti4+ on the long lasting luminescence of Sr2SiO4:Eu2+
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High pressure studies of Eu2+ and Mn2+ doped NaScSi2O6 clinopyroxenes
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A rapid spectrofluorimetric method for the determination of malondialdehyde in human plasma after its derivatization with thiobarbituric acid and vortex assisted liquid–liquid microextraction
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Interrelated shape memory and Payne effect in polyurethane/graphene oxide nanocomposites
PublicationWe report the fabrication of graphene oxide (GO) based polyurethane (PU) nanocomposites by a simple method of mixing and their shape memory properties at different temperatures. Both the polymer and the filler were synthesized in the laboratory by simple and easy methods – PU by pre-polymer method and GO by improved graphene oxide synthesis method. High molecular level dispersion of GO platelets within the PU matrix and thus good...
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New clicked full agonists of the estrogen receptor β
PublicationA click chemistry approach was used to synthesize a series of 1,4-diaryl-substituted 1,2,3-triazoles designed to behave as estrogen receptor (ER) ligands. We studied their affinities for both receptors α and β, their agonist activities in a cell-based luciferase reporter assay and their effect on the proliferation of the hormone-dependent MCF-7 cell line. We found two compounds (3a and 3c) that behave as selective full agonists...
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Aquatic biomass containing porous silica as an anode for lithium ion batteries
PublicationA composite electrode was manufactured by pyrolysis of Red Algae (Polysiphonia fucoides) covered by diatoms (Diatomophyceae). Electrodes were tested as a half cell with capacity of 500 mA h g−1 after 80 cycles. XPS analysis shows formation of lithium silicate under reduction of silica in an aprotic electrolyte containing LiPF6 salt.
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The role of fluids in high-pressure polymorphism of drugs: different behaviour of β-chlorpropamide in different inert gas and liquid media
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Modification of Rapana thomasiana hemocyanin with choline amino acid salts significantly enhances its antiproliferative activity against MCF-7 human breast cancer cells
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Novel isatin–indole derivatives as potential inhibitors of chorismate mutase (CM): their synthesis along with unexpected formation of 2-indolylmethylamino benzoate ester under Pd–Cu catalysis
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