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Catalog Publications

Year 2016
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Year 2015
  • 5-Thiocyanato-2′-deoxyuridine as a possible radiosensitizer: electron-induced formation of uracil-C5-thiyl radical and its dimerization
    Publication
    • M. Zdrowowicz
    • L. Chomicz
    • M. Żyndul
    • P. Wityk
    • J. Rak
    • T. Wiegand
    • C. Hanson
    • A. Adhikary
    • M. Sevilla

    - PHYSICAL CHEMISTRY CHEMICAL PHYSICS - Year 2015

    In this work, we have synthesized 5-thiocyanato-2′-deoxyuridine (SCNdU) along with the C6-deuterated nucleobase 5-thiocyanatouracil (6-D-SCNU) and studied their reactions with radiation-produced electrons. ESR spectra in γ-irradiated nitrogen-saturated frozen homogeneous solutions (7.5 M LiCl in H2O or D2O) of these compounds show that electron-induced S–CN bond cleavage occurs to form a thiyl radical (dU-5-S˙ or 6-D-U-5-S˙) and...

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  • Approaches to Static Digestion Models
    Publication

    - Year 2015

    It is not possible to look in detail at the wide range of static digestion methods that have been used to date. However, this section looks at some of the general approaches that have been used to look at the digestion of various nutrients and bioactives. I have focussed on the two main nutrients that undergo digestion in the upper GI tract, namely protein and lipid. In the case of protein, the research has largely been driven...

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