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Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivatives
PublikacjaThree structurally related oxathiolone fused chalcone derivatives appeared effective chemosensitizers, able to restore in part sensitivity to fluconazole of multidrug-resistant C.albicans strains. Compound 21 effectively chemosensitized cells resistant due to the overexpression of the MDR1 gene, compound 6 reduced resistance of cells overexpressing the ABC-type drug transporters CDR1/CDR2 and derivative 18 partially reversed fluconazole...
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Voriconazole-Based Salts Are Active against Multidrug-Resistant Human Pathogenic Yeasts
PublikacjaVoriconazole (VOR) hydrochloride is unequivocally converted into VOR lactates and valinates upon reaction with silver salts of organic acids. This study found that the anticandidal in vitro activity of these compounds was comparable or slightly better than that of VOR. The Candida albicans clinical isolate overexpressing CaCDR1/CaCDR2 genes, highly resistant to VOR, was apparently more susceptible to VOR salts. On the other hand,...
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Flow Boiling in Minigap in the Reversed Two-Phase Thermosiphon Loop
PublikacjaThe paper presents the results of experimental investigations of a model of a heat exchanger featuring a minigap, which is perceived as an evaporator for an inverted thermosiphon. The system works with a single component test fluid. The tested evaporator generates pumping power in the test loop in a way similar to the mammoth pump. The tests regarded a module of the heat exchanger, consisting of a hot leg and a cold leg with the...
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Wpływ właściwości cieczy hydraulicznej na wartość skoków ciśnienia w komorach pomp tłoczkowych osiowych
PublikacjaPublikacja dotyczy badań skoków ciśnienia w komorach roboczych pomp tłoczkowych osiowych. Skupiono się w nim na wpływie właściwości cieczy hydraulicznej na wartość skoków ciśnienia. Przeanalizowano wpływ takich parametrów jak: -gęstość, -lepkość, -ściśliwość, -zapowietrzenie. Do określenia wpływu właściwości cieczy na skoki ciśnienia wykorzystano badania laboratoryjne i symulacje komputerowe.
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Kompensacja skoków ciśnienia w pompie tłoczkowej o zmiennej wydajności z rozrządem krzywkowym
PublikacjaPrzedmiotem rozprawy doktorskiej jest opis matematyczny, badania i symulacja mechanizmu kompensacji skoków ciśnienia w pompie tłoczkowej z rozrządem krzywkowym typu PWK. W rozprawie przedstawiono istniejące rozwiązania konstrukcyjne pomp tłokowych, kładąc szczególny nacisk na przedstawienie stosowanych w nich mechanizmów rozrządu i kompensacji skoków ciśnienia. Ponadto szczegółowo opisano budowę i zasadę działania pompy PWK będącej...
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Wielopoziomowe przekształtniki średniego napięcia (SN) o budowie modułowej
PublikacjaW artykule omówiono wybrane zagadnienia dotyczące zastosowań wielopoziomowych przekształtników średniego napięcia (SN) w układach napędowych o regulowanej prędkości, zwłaszcza w układach z izolacją od sieci zasilającej. W opracowanym przekształtniku zastosowano izolację galwaniczną od sieci zrealizowaną za pomocą izolowanych przetwornic dc-dc z transformatorami wysokiej częstotliwości (> 5 kHz). Przedstawiono zarejestrowane przebiegi...
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Two-phase water-air flow measurement using gamma-ray absorption technique – plug flow
Dane BadawczeThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: plug flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded using a dedicated EC...
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Two-phase water-air flow measurement using gamma-ray absorption technique – slug flow
Dane BadawczeThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: slug flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded using a dedicated EC...
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Two-phase water-air flow measurement using gamma-ray absorption technique – transitional plug – bubble flow
Dane BadawczeThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: transitional plug – bubble flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded...
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Two-phase water-air flow measurement using gamma-ray absorption technique –bubble flow
Dane BadawczeThe attached datasets contains the measurement results of the air-water flow in a horizontal pipeline. Flow type: bubble flow. The data shows the pulse counts of the two radiometric sets. Each of these kits consisted of a QSA Global Am-241 gamma ray source and a Tesla SKG-1 type NaI(Tl) scintillation probe. The pulses were recorded using a dedicated...
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Numeryczna analiza możliwości zwiększenia efektywności grzewczej pompy ciepła, poprzez modyfikację skraplacza
PublikacjaW niniejszej pracy określono charakterystykę prostego modelu wymiennika ciepła bazującego na skraplaczu powietrznej pompy ciepła. Jest to helikoidalny rekuperator typu rura w rurze. Zaproponowano i poddano analizie numerycznej dwie metody intensyfikacji wymiany ciepła i zestawiono wyniki z modelem porównawczym. Zastosowane rozwiązania zwiększające strumień wymienianego ciepła spowodowały wzrost odbieranego przez wodę strumienia...
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Lab-in-syringe as a practical technique for automatic microextraction: Evaluation by Blue Applicability Grade Index
PublikacjaLab-in-syringe (LIS) is a powerful automatic technique that is derived from sequential injection analysis. In LIS, a computer-controlled syringe pump is employed, and its syringe barrel serves as a mixing, reaction, and/or extraction chamber. Until now, the LIS concept has been efficiently employed for the automation of solid-phase microextraction and liquid-phase microextraction protocols as a front-end to a plethora of chromatographic...
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Synthesis Methods and Favorable Conditions for Spherical Vaterite Precipitation: A Review
PublikacjaVaterite is the least thermodynamically stable anhydrous calcium carbonate polymorph. It exists very rare in nature, e.g. in some rock formations or as a component of biominerals produced by some fishes, crustaceans or birds. Synthetic vaterite particles are proposed as carriers of active substances in medicines, additive in cosmetic preparations as well as adsorbents. Also, their utilization as a pump for microfluidic flow is...
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APPLICATION OF THE THEORY OF SEMI-MARKOV PROCESSES TO DETERMINE A LIMITING DISTRIBUTION OF THE PROCESS OF CHANGES OF ABILITY AND INABILITY STATES OF FUEL SUPPLY SYSTEMS IN HEAVY FUEL DIESEL ENGINES
PublikacjaThe paper presents applicability of the theory of semi-Markov processes to determine a limiting distribution of the process of changes of technical states of fuel systems for marine engines running on heavy fuel oils. The proposed study of this process includes the components of such fuel systems like: 1 - injectors, 2 - high pressure hoses, 3 - injection pumps, 4 - low pressure hoses, 5 – fine filters, 6 - coarse filters, 7 – fuel-feed...
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Validation of atmospheric aerosols parallel sampling in a multifold device
PublikacjaIn this work, particulate matter was collected using an active sampling system consisting of a PM10 (<10 μm) inlet coupled to a multifold device containing six channels, connected to a vacuum pump. Each channel was equipped with a filter holder fitted with adequately chosen filters. The system was fixed on a metallic structure, which was placed on the roof of the laboratory building, at the Faculty of Sciences, in Lisbon. Sampling...
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Początek Gdyńskiego Systemu Wodociągowego Planowanie i budowa lokalnego układu wodociągowego na Kępie Oksywskiej (1929 – 1932. Część II.
PublikacjaUdokumentowanie procesu inwestycyjnego przekształcenia wodociągu wiejskiego w miejski układ wodociągowy na podstawie analizy materiałów źródłowych. Ustalenie hydrogeologicznych uwarunkowań decyzji o lokalizacji ujęcia wody „Oksywie”. Identyfikacja parametrów konstrukcyjnych i kosztów budowy trzech budynków na ujęciu wody: mieszkalnego, stacji pomp i odżelaziania wody. Odtworzenie przebiegu budowy struktury sieci wodociągowej w...
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Arterial cannula shape optimization by means of the rotational firefly algorithm
PublikacjaThe article presents global optimization results of arterial cannula shapes by means of the newly modified firefly algorithm. The search for the optimal arterial cannula shape is necessary in order to minimize losses and prepare the flow that leaves the circulatory support system of a ventricle (i.e. blood pump) before it reaches the heart. A modification of the standard firefly algorithm, the so-called rotational firefly algorithm,...
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Pipeline System for Heat Transportation from Nuclear Power Plant – an Optimizing Approach
PublikacjaOver the last few years heat piping insulation technology and pump systems efficiency have been significantly improved. Reduced thermal losses encourage heat transportation over long distances. It provides an opportunity for increasing thermodynamic efficiency of Nuclear Power Plants (NPPs) that are often located in rural areas because of safety issues. It can be achieved by Combined Heat and Power (CHP) generation, as heat produced...
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DIGITAL HYDRAULICS CIRCUIT BASED ON PWM FUNCTION FOR CONTROLLING HYDRAULIC ACTUATOR POSITION
PublikacjaHydraulic systems are used in many different industries, such as multi-source hydrostatic drive systems. In traditional hydraulic systems, a proportional servo valve is used to control the position of hydraulic actuators. The low energy efficiency and high cost of these control valves are two major problems with these systems. Digital hydraulics is one of the most unique ideas on how to solve these problems. Researchers like digital...
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Portable exhaled breath analyzer employing fluctuation-enhanced gas sensing method in resistive gas sensors
PublikacjaThis paper presents a portable exhaled breath analyser, developed to detect selected diseases. The set-up employs resistive gas sensors: commercial MEMS sensors and prototype gas sensors made of WO3 gas sensing layers doped with various metal ingredients. The set-up can modulate the gas sensors by applying UV light to induce physical changes of the gas sensing layers. The sensors are placed in a tiny gas chamber of a volume...
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The new concept of capillary forces aided evaporator for application in domestic organic rankine cycle
PublikacjaThis paper presents studies on the possibility of applying capillary forces induced in the porous structure to a modern design of evaporator. The potential application of such heat exchanger is for example an evaporator of the domestic micro combined heat and power (CHP) unit. One of the problems in the micro-CHP is excessive demand for pumping power. The proposed design helps in overcoming that issue. In the evaporator outlined...
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KONCEPCJA DWU-ŚMIGŁOWEJ ELEKTROWNI WIATROWEJ I ELEKTROWNI SZCZYTOWO-POMPOWEJ NA WZGÓRZU SZUBIENICZNYM
PublikacjaDogodne warunki terenowe Wzgórza Szubienicznego w Gdańsku oraz istniejąca tam infrastruktura stanowią podstawę do rozważenia koncepcji doposażenia instalacji badawczej Laboratorium Innowacyjnych Technologii Elektroenergetycznych i Integracji Odnawialnych Źródeł Energii LINTE^2 w skojarzony, hydro-wiatrowy zespół wytwórczy. W artykule zaproponowano koncepcję budowy elektrowni pompowo-szczytowej z turbinami Francisa oraz elektrowni...
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Starter for Voltage Boost Converter to Harvest Thermoelectric Energy for Body-Worn Sensors
PublikacjaThis paper examines the suitability of selected configurations of ultra-low voltage (ULV) oscilla-tors as starters for a voltage boost converter to harvest energy from a thermoelectric generator (TEG). Important properties of particularly promising configurations, suitable for on-chip imple-mentation are compared. On this basis, an improved oscillator with a low startup voltage and a high output voltage swing is proposed. The applicability...
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Low-Voltage LDO Regulator Based on Native MOS Transistor with Improved PSR and Fast Response
PublikacjaIn this paper, a low-voltage low-dropout analog regulator (ALDO) based on a native n-channel MOS transistor is proposed. Application of the native transistor with the threshold voltage close to zero allows elimination of the charge pump in low-voltage regulators using the pass element in a common drain configuration. Such a native pass transistor configuration allows simplification of regulator design and improved performance,...
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Properties of New Composite Materials Based on Hydroxyapatite Ceramic and Cross-Linked Gelatin for Biomedical Applications
PublikacjaThe main aim of the research was to develop a new biocompatible and injectable composite with the potential for application as a bone-to-implant bonding material or as a bone substitute. A composite based on hydroxyapatite, gelatin, and two various types of commercially available transglutaminase (TgBDF/TgSNF), as a cross-linking agent, was proposed. To evaluate the impacts of composite content and processing parameters on various...
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Geometric working volume of a satellite positive displacement machine
PublikacjaThis article describes a method for determining the geometric working volume of satellite positive displacement machines (pump and motor). The working mechanism of these machines is satellite mechanism consisting of two non-circular gears (rotor and curvature) and circular gears (satellites). Two variants of the satellite mechanism are presented. In the first mechanism, the rolling line of the rotor is a sinusoid "wrapped" around...
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Numerical analysis of vacuum drying of a porous body in the integrated domain
Publikacjan the present study, the vacuum drying process of an apple slice is numerically modeled based on a control volume method. Transient two-dimensional Navier– Stokes, energy, moisture, and Luikov equations are solved by numerical coding (Fortran) to simulate the simultaneous heat and mass transfer in the ambient and apple slice, respectively. The privilege of using Luikov's model is that the capillary forces are considered, and a...
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Comparative study of numerical modelling and experimental investigation for vessel-docking operations
PublikacjaA comparative study between numerical modelling and experimental investigation is performed to validate the developed numerical method for simulating floating dock operations with a vessel on board. Both model-scale and full-scale experimental tests are performed on floating docks with a vessel on board, and the draughts using draught meters, floating positions and bending of the floating dock are measured. The present numerical...
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Chemical Theory of Machines, basic principles of strength with examples of calculations
PublikacjaThis book encompasses the essential range of information on technical aspects of mechanical design. It was written primarily for the students and staff of chemistry faculties of technical universities, yet it may also be utilized by everyone, who ether would like to try or already enjoys designing, but cannot take advantage of typical stress & machine construction handbooks. These handbooks often require familiarity with the concepts...
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Research on water lubricated main shaft bearings in conditions of improper lubrication and cooling conducted on high torque real-life scale bush test rig
PublikacjaWater lubricated polymer bushes find increasingly popular use in the sliding bearings of marine propellers, water turbines and pump shafts. Such popularity is partly due to their simple construction which also means relatively affordable price. In addition, properly designed and installed water lubricated bearings may well last for over a decade. However, in practical experience one may also observe cases of rapid wear...
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PROBLEMS OF THE STARTING AND OPERATING OF HYDRAULIC COMPONENTS AND SYSTEMS IN LOW AMBIENT TEMPERATURE (PART IV) MODELLING THE HEATING PROCESS AND DETERMINING THE SERVICEABILITY OF HYDRAULIC COMPONENTS DURING THE STARTING-UP IN LOW AMBIENT TEMPERATURE
PublikacjaDesigners of hydraulically driven machines and devices are obliged to ensure during design process their high service life with taking into account their operational conditions. Some of the machines may be started in low ambient temperature and even in thermal shock conditions (due to delivering hot working medium to cold components). In order to put such devices into operation appropriate investigations, including experimental...
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The experimental results of diesel fuel spray with marine engine injector
Dane BadawczeThe data set presents the measurement of the diesel fuel spray from with marine engine injector. The main target presents results is a study of the time course of macro parameters (spray tip penetration, spray cone angle) of fuel spray in the cylinder of marine diesel engine. The impact of ambient conditions and the geometrical parameters of the injector...
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Mechanisms of azole resistance among clinical isolates of Candida glabrata in Poland
PublikacjaCandida glabrata is currently ranked as the second most frequently isolated aetiological agent of human fungal infections, next only to Candida albicans. In comparison with C. albicans, C. glabrata shows lower susceptibility to azoles, the most common agents used in treatment of fungal infections. Interestingly, the mechanisms of resistance to azole agents in C. albicans have been much better investigated than those in C. glabrata....
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Correlation between the number of Pro-Ala repeats in the EmrA homologue of Acinetobacter baumannii and resistance to netilmicin, tobramycin, imipenem and ceftazidime
PublikacjaAcinetobacter baumannii coccobacilli are dangerous to patients in intensive care units because of their multidrug resistance to antibiotics, developed mainly in the past decade. This study aimed to examine whether there is a significant correlation between the number of Pro-Ala repeats in the CAP01997 protein, the EmrA homologue of A. baumannii, and resistance to antibiotics. A total of 79 multidrug-resistant A. baumannii strains...
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Magnetic field mapping along a NV-rich nanodiamond-doped fiber
PublikacjaIntegration of NV−-rich diamond with optical fibers enables guiding quantum information on the spin state of the NV− color center. Diamond-functionalized optical fiber sensors have been demonstrated with impressive sub-nanotesla magnetic field sensitivities over localized magnetic field sources, but their potential for distributed sensing remains unexplored. The volumetric incorporation of diamonds into the optical fiber core allows...
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Load effect impact on the exploitation of concrete machine foundations used in the gas and oil industry
PublikacjaMachine foundations is a critical topic in the gas and oil industry, which design and exploitation require extensive technical knowledge. Machine foundations are the constructions which are intended for mounting on it a specific type of machine. The foundation has to transfer dynamic and static load from machine to the ground. The primary difference between machine foundations and building foundations is that the machine foundations...
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Audible noise in ship’s electrical drive systems with frequency converters
Dane BadawczeThe presented dataset is part of research focusing on the impact of the ship's electrical drive systems with frequency converters on vibrations and the level of audible noise on ships.
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Jan Wajs dr hab. inż.
Osoby -
Combinated treatment of landfill leachates with wastewater in a sequencing batch reactor (SBR)
PublikacjaSanitary landfill leachates are treated usually by multistage systems using physical, chemical and biological processes. One of the most economic and efficient method is combined treatment of landfill leachates with municipal wastewater in a sequencing batch reactor (SBR. The main advantage of such co-treatment is that landfill leachates variability (in quality and quantity) do not influence the effectiveness of biological processes....
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Funkcjonowanie zespołów napędu hydraulicznego maszyn w niskich temperaturach otoczenia
PublikacjaW pracy przedstawiono cztery warianty klasyfikacji rozruchów oziębionego napędu hydraulicznego. Pierwsza sytuacja dotyczy zagadnienia, w którym wszystkie zespoły układu napędowego wraz z olejem mają taką samą niską temperaturę podczas rozruchu. Pozostałe warianty odnoszą się do rozruchu w warunkach szoku termicznego wywołanych zasilaniem ciepłym czynnikiem roboczym oziębionych zespołów hydraulicznych. Rozruch zespołów...
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Turbomachinery - Background
PublikacjaThe "Turbomachinery - Background" is the first part of a series of monographs devoted to different aspects of rotating machines. The book presents the main fundamentals which are necessary for the different problems of steam, gas, wind and water turbines as well as pumps, compressors and propellers which will discussed in detail in the subsequent parts of the series.
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Zakład Hydrauliki i Pneumatyki
Zespoły BadawczePrace badawcze i rozwojowe pomp wyporowych, silników hydraulicznych i zaworów z zastosowaniem oleju mineralnego i wody jako cieczy roboczych.