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Wyniki wyszukiwania dla: experimental testing
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Ultra-rare ultra-care: The unique burden of ultra rare disease caregiving
PublikacjaBackground: We sought to assesses the impact of caring for children with ultra rare diseases (URDs) on familycarers and to analyse the way these experiences differ among the caregivers of children diagnosed throughprenatal or newborn screening, and those with symptom-based diagnosis.Methods: A total of 200 caregivers of 219 URDs children completed an on-line survey regarding the challengesand experiences...
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How to enhance perception of reassembled but incomplete works of ancient art? Eye-tracking study of virtual anastylosis.
Publikacjan 1964 the Venice Charter described anastylosis as the only acceptable method of reassembly of architectural remains. Although the scientific community has agreed with the Charter’s decision, many questions pertaining to the technical and aesthetic aspects of anastylosis remain unanswered. Virtual anastylosis seems one of the most promising digital solutions to finding at least some answers, as it permits testing various solutions...
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Polymer based thick films - material quality and interface resistance evaluation
PublikacjaThe properties of polymer based thick film layers mede using different resistive pastes and dipping silvers have been studied. The composite of carbon and graphite (C/Gr) conducting particles suspended in different polymer vehicles were used for preparation resistive layers. Interface resistance Rc created between dipping silver (DiAg) contact layer and resistive layer was determined from the surface potential distribution measurements...
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Temperature influence on tyre/road noise on poroelastic road surface based on laboratory measurements
PublikacjaThe temperature effect on measured tyre/road noise is very important phenomena as it may lead to significant errors in measurement results due to substantial influence of this parameter on the obtained values. It depends mainly on the particular tyre-road combination. It is different for dense and porous as well as for bituminous and cement concrete pavements. It differs also depending on tested tyre. The correction procedure for...
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A novel in vitro assay for assessing efficacy and toxicity of antifungals using human leukaemic cells infected with Candida albicans
PublikacjaAims: This study describes a novel in vitro assay that simultaneously determines antifungal efficiency and host cell toxicity using suspensions of human leukaemic cells (HL-60) infected with Candida albicans. Methods and Results: The effect of Candida infection on host cell viability was evaluated by the microscopy of trypan blue-stained cells and lactate dehydrogenase (LDH) activity. The in vitro ‘drug potency assay’ utilized...
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Semantic Analysis and Text Summarization in Socio-Technical Systems
PublikacjaIn this chapter the authors present the results of the development the methodology for increasing the reliability of the functioning of the Socio-Technical System. The existed methods and algorithms for processing unstructured (textual) information were studied. Taking into account noted above strengths and weaknesses of Discriminant and Probabilistic approaches of Latent Semantic Relations analysis in of the summarization projection...
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Investigations on the immunosuppressive activity of derivatives of mycophenolic acid in immature dendritic cell
PublikacjaThe main activity of mycophenolic acid (MPA) and its analogs is the inhibition of proliferation of T cells. Here, we hypothesized that MPA and its conjugates inhibits also the activity of antigen-presenting cells (APC) including dendritic cells (DCs). We tested the effect of novel amino acid derivatives of MPA and conjugates of MPA with acridines/acridones on DCs by flow cytometry, ELISA and MLR assay. Both acridines/acridone derivatives...
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Novel fast analytical method for indirect determination of MCPD fatty acid esters in edible oils and fats based on simultaneous extraction and derivatization
PublikacjaA novel method for indirect determination of MCPD esters levels in lipid samples has been developed. The method is based on combination of extraction and derivatisation in the same sample preparation step. It is achieved by the application of diethyl ether as extraction solvent for isolation of released from esterified forms analytes from water phase and dilution solvent for solid PBA – derivatisation agent. It is a noteworthy...
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Mobile inventory system for hydrotechnical objects using data from multiple sensors operating simultaneously
PublikacjaThe knowledge of the location, shape and other characteristics of spatial objects in the coastal areas has a significant impact on the functioning of ports, shipyards, and other water-infrastructure facilities, both offshore and inland. Therefore, measurements are taken of the underwater part of the waterside zone, which means the bottom of water and other underwater objects (e.g. breakwaters, docks, etc.), and objects above the...
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Curing characteristics, mechanical properties and morphology of butyl rubber filled with ground tire rubber (GTR)
PublikacjaThe results on testing application of ground tire rubber (GTR), as potential filler for butyl rubber, are pre- sented. The GTR content variation, within the range of 10–90 phr, was studied with respect to the vulcanization process, static mechanical properties (tensile strength, elongation-at-break, hardness and resilience), dynamic mechanical properties and the morphology of the obtained vulcanizates. Butyl rubber was characterized...
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Efficiency of thermomechanical reclaiming of ground tire rubber conducted in counter-rotating and co-rotating twin screw extruder
PublikacjaIn this article the results of research on a continuous thermomechanical reclaiming process of ground tire rubber (GTR) conducted in a twin screw extruder are presented. The effects of the rotation direction (co-rotating/counter-rotating), design of co-rotating plasticizing units and the rotational speed of the screws on the extruder working parameters, sol fraction and the degree of reclaiming in the obtained products were described....
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Inhibiting activity of HIV-1: protease, reverse transcriptase and integrase all together by novel compounds using computational approaches (flexible and rigid docking)
PublikacjaAcquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus type 1 (HIV-1) infection, is one of the most challenging diseases in recent decades. Nevertheless the shortcomings of chemical drugs such as toxicity, lack of curative effects, the search for more potent anti-HIV agents have been focused in our study. In current study, novel scaffold was designed having a benzyl and imidazole in it which are very...
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Multi-layered tissue head phantoms for noninvasive optical diagnostics
PublikacjaExtensive research in the area of optical sensing for medical diagnostics requires development of tissue phantoms with optical properties similar to those of living human tissues. Development and improvement of in vivo optical measurement systems requires the use of stable tissue phantoms with known characteristics, which are mainly used for calibration of such systems and testing their performance over time. Optical and mechanical...
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Interactive Prototypes in Teaching User-Centred Design and Business Process Modelling
PublikacjaThis publication describes experiences gathered during the use of interactive prototyping in two areas: design of user interfaces for a touch screen information kiosk and interactive prototyping of business processes. Prototyping is promoted here as a technique useful for both visualizing design concepts and for stimulating communication within relevant teams. Developing interactive prototypes of use interfaces is discussed here...
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Assessment of Wide-Sense Stationarity of an Underwater Acoustic Channel Based on a Pseudo-Random Binary Sequence Probe Signal
PublikacjaThe performances of Underwater Acoustic Communication (UAC) systems are strongly related to the specific propagation conditions of the underwater channel. Designing the physical layer of a reliable data transmission system requires a knowledge of channel characteristics in terms of the specific parameters of the stochastic model. The Wide-Sense Stationary Uncorrelated Scattering (WSSUS) assumption simplifies the stochastic description...
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The abrasive wear resistance of coatings manufactured on high-strength low-alloy (HSLA) offshore steel in wet welding conditions
PublikacjaSome marine and offshore structure elements exploited in the water cannot be brought to the surface of the water as this will generate high costs, and for this reason, they require in-situ repairs. One of the repair techniques used in underwater pad welding conditions is a wet welding method. This paper presents an investigation of the abrasive wear resistance of coatings made in wet welding conditions with the use of two grades...
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Direction of Arrival Estimation Based on Received Signal Strength Using Two-Row Electronically Steerable Parasitic Array Radiator Antenna
PublikacjaIn this paper, we present a novel approach to direction-of-arrival (DoA) estimation using two-row electronically steerable parasitic array radiator (ESPAR) antenna which has 12 passive elements and allows for elevation and azimuth beam switching using a simple microcontroller, relying solely on received signal strength (RSS) values measured at the antenna output port. To this end, we thoroughly investigate all 18 available 3D antenna...
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Regenerative Drug Discovery Using Ear Pinna Punch Wound Model in Mice
PublikacjaThe ear pinna is a complex tissue consisting of the dermis, cartilage, muscles, vessels, and nerves. Ear pinna healing is a model of regeneration in mammals. In some mammals, including rabbits, punch wounds in the ear pinna close spontaneously; in common-use laboratory mice, they remain for life. Agents inducing ear pinna healing are potential regenerative drugs. We tested the effects of selected bioactive agents on 2 mm ear pinna...
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Enhanced susceptibility of SARS-CoV-2 spike RBD protein assay targeted by cellular receptors ACE2 and CD147: Multivariate data analysis of multisine impedimetric response
PublikacjaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells through the binding of spike protein to the host cell surface-expressing angiotensin-converting enzyme 2 (ACE2) or by endocytosis mediated by extracellular matrix metalloproteinase inducer (CD147). We present extended statistical studies of the multisine dynamic electrochemical impedance spectroscopy (DEIS) revealing interactions between Spike RBD and...
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Assessing the attractiveness of human face based on machine learning
PublikacjaThe attractiveness of the face plays an important role in everyday life, especially in the modern world where social media and the Internet surround us. In this study, an attempt to assess the attractiveness of a face by machine learning is shown. Attractiveness is determined by three deep models whose sum of predictions is the final score. Two annotated datasets available in the literature are employed for training and testing...
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Fabrication of the cross-linked PVA/TiO2/C nanocomposite membrane for alkaline direct methanol fuel cells
PublikacjaA crosslinked Poly(vinyl alcohol) based composite membrane was developed through a phase inversion process for use in alkaline direct methanol fuel cells (ADMFCs). The titanium dioxide (TiO2) and carbon nanoparticles (NPs) have been incorporated into the PVA polymer matrix to improve the mechanical and thermal properties. The membrane samples were further modified with maleic acid, a carboxylic acid acting as the cross-linker,...
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Using Convolutional Neural Networks for Corneal Arcus Detection Towards Familial Hypercholesterolemia Screening
PublikacjaFamilial hypercholesterolemia (FH) is a highly undiagnosed disease. Among FH patients, the onset of premature coronary artery disease is 13 times higher than in the general population. Early diagnosis and treatment is essential to prevent cardiovascular diseases and their complications, and to prolong life. One of the clinical criteria of FH is the occurrence of a corneal arcus (CA) among patients, especially those under 45 years...
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Towards classification of patients based on surface EMG data of temporomandibular joint muscles using self-organising maps
PublikacjaThe study considers the need for an effective method of classification of patients with a temporomandibular joint disorder (TMD). The self-organising map method (SOM) was applied to group patients and used together with the cross-correlation approach to interpret the processed (rectified and smoothed by using root mean square (RMS) algorithm) surface electromyography signal (sEMG) obtained from testing the muscles (two temporal...
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Tensile modulus of human orbital wall bones cut in sagittal and coronal planes
PublikacjaIn the current research, 68 specimens of orbital superior and/or medial walls taken from 33 human cadavers (12 females, 21 males) were subjected to uniaxial tension untill fracture. The samples were cut in the coronal (38 specimens) and sagittal (30 specimens) planes of the orbital wall. Apparent density (ρapp), tensile Young’s modulus (E-modulus) and ultimate tensile strength (UTS) were identified. Innovative test protocols were...
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Integrating Digital Twin Technology Into Large Panel System Estates Retrofit Projects
PublikacjaAs sustainability is now a standard for the proposed developments, the focus ought to be shifted towards the existing buildings and, among them, the worldwide stock of large panel system (LPS) buildings. Major upgrades and retrofits were done to some of the LPS estates in Germany and France, but a leading sustainable way must still be developed for LPS buildings in Eastern European countries, where apartments in those half‐a‐century‐old...
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Microstructure and Mechanical Properties of Combined GTAW and SMAW Dissimilar Welded Joints between Inconel 718 and 304L Austenitic Stainless Steel
PublikacjaA dissimilar welded joint of Inconel 718 and 304L austenitic stainless steel was prepared using a combined procedure with the gas tungsten arc welding and shielded metal arc welding processes by employing the Ni-based fillers: ERNiCr-3 and ENiCrFe-3. The welded joints were investigated for metallographic testing and mechanical properties, and a relationship was established between the microstructure and the resultant mechanical...
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Sustainable utilization of copper post-flotation waste in cement composites
PublikacjaThe current way of managing the copper ore flotation waste is by placing it in waste neutralization facilities. However, flotation waste has great potential in application in cement composites. The article presents the detailed characteristics of post-flotation waste (PFW) and three types of cements: CEM I, CEM II/B-V, and CEM III/A, 42.5 MPa class. The post-flotation waste added for 20% of the cement mass increase the water demand...
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The In-House Method of Manufacturing a Low-Cost Heat Pipe with Specified Thermophysical Properties and Geometry
PublikacjaVarious types of heat pipes are available to purchase off the shelf, from various manufacturers, but most of them have strictly defined geometry and technical parameters. However, when there is a need to use a heat pipe (HP) with an unusual size and shape or working conditions other than the standard ones, it becomes very costly to order them from manufacturers, especially in small quantities, and only a few producers are willing...
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Phosphorus concentration and availability in raw organic waste and post fermentation products
PublikacjaThe aim of the study was to determine the mobility of phosphorus forms in raw organic waste and from the solid and liquid fractions of digestate. To achieve the purpose of this study, the components (including livestock manure, agricultural waste, food waste, sewage sludge) and their post fermentation products were considered. Subsequently, the effect of the fermentation process on the mobility of phosphorus forms in post-fermentation fractions...
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Drill holes decrease cancellous bone strength: A comparative study of 33 paired osteoporotic human and 9 paired artificial bone samples
PublikacjaThis study was designed to compare compressive strength of cancellous bone retrieved from the femoral head in a specimen with and without guide wire hole, with comparison to synthetic bone samples. Femoral heads retrieved from 33 patients who sustained femoral neck fractures and underwent hip arthroplasty were cut into cuboids leaving two matching samples from the same femoral head. Similar samples were prepared from synthetic femurs....
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Nanosilver-loaded PMMA bone cement doped with different bioactive glasses – evaluation of cytocompatibility, antibacterial activity, and mechanical properties
PublikacjaNanosilver-loaded PMMA bone cement (BC-AgNp) is a novel cement developed as a replacement for conventional cements. Despite favorable properties and antibacterial activity, BC-AgNp still lacks biodegradability and bioactivity. Hence, we investigated the doping with bioactive glasses (BGs) to create a new bioactive BC characterized by time-varying porosity and gradual release of nanosilver. The BC Cemex was used as the base material...
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Hybrid no-signaling-quantum correlations
PublikacjaFundamental investigations in non-locality have shown that while the no-signaling principle alone is not sufficient to single out the set of quantum non-local correlations, local quantum mechanics and no-signaling together exactly reproduce the set of quantum correlations in the two-party Bell scenario. Here, we introduce and study an intermediate hybrid no-signaling quantum set of non-local correlations that we term HNSQ in the...
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NEW EXPERIENCES IN DIKE CONSTRUCTION WITH SOIL-ASH COMPOSITESAND FINE-GRAINED DREDGED MATERIALS
PublikacjaThe supporting structure inside a coastal dike is often made of dredged non-uniform sand with good compaction proper-ties. Due to the shortage of natural construction material for both coastal and river dikes and the surplus of different processed mate-rials, new experiments were made with sand-ash mixtures and fine-grained dredged materials to replace both dike core and dikecover materials resulting in economical, environmentally...
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The application of non-destructive methods in the diagnostics of the approach pavement at the bridges
PublikacjaThe article presents the possibility of using non-destructive methods of road pavement diagnostics as an alternative to traditional means to assess the reasons for premature cracks adjacent to bridge objects. Two scanning methods were used: laser scanning to measure geometric surface deformation and ground penetrating radar (GPR) inspection to assess the road pavement condition. With the use of a laser scanner, an effective tool...
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Pantographic metamaterials: an example of mathematically driven design and of its technological challenges
PublikacjaIn this paper, we account for the research efforts that have been started, for some among us, already since 2003, and aimed to the design of a class of exotic architectured, optimized (meta) materials. At the first stage of these efforts, as it often happens, the research was based on the results of mathematical investigations. The problem to be solved was stated as follows: determine the material (micro)structure governed by those...
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Zastosowanie georadaru do badań muru ceglanego
PublikacjaPostęp technologiczny w dziedzinie diagnostyki konstrukcji badaniami nieniszczącymi NDT (z ang. nondestructive testing) pozwala na coraz dokładniejsze określenie stanu technicznego danej konstrukcji. Jedną z tego rodzaju technik jest metoda georadarowa należąca do grupy metod elektromagnetycznych. Wykorzystuje ona zjawisko odbicia fali elektromagnetycznej na granicy ośrodków o różnych właściwościach elektrycznych. Metoda znalazła...
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SILICA AEROGEL TOWARDS ANODES FOR LITHIUM-ION BATTERIES
PublikacjaAn increasing demand for electrochemical energy storage and conversion devices stimulates progress in research on electrode and electrolyte materials. In the field of electrodes materials, silicon is the one of the most promising anode materials for Li-ion batteries. However silicon has the drastic volume variation (around 3 times lower on extraction) during insertion and extraction of lithium ions. As an alternative, nanocomposites...
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Bioactive and bioavailability of minerals in rats loaded with cholesterol and kiwi fruit
PublikacjaThe aim of this study was to compare the content of polyphenols (TP), minerals, ascorbic acid (AA) and total antioxidant capacities (TAC) of conventional and organic kiwifruit ‘Hayward’ treated with ethylene after harvest and to determine their influence on plasma TAC, mineral content in the liver and bioavailability (RBV — relative bioavailability value) in rats fed diet containing cholesterol. Organic and conventionally grown...
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Investigating the Impact of Curing System on Structure-Property Relationship of Natural Rubber Modified with Brewery By-Product and Ground Tire Rubber
PublikacjaThe application of wastes as a filler/reinforcement phase in polymers is a new strategy to modify the performance properties and reduce the price of biocomposites. The use of these fillers, coming from agricultural waste (cellulose/lignocellulose-based fillers) and waste rubbers, constitutes a method for the management of post-consumer waste. In this paper, highly-filled biocomposites based on natural rubber (NR) and ground tire...
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Refinement of the Hardening Soil model within the small strain range
PublikacjaThe popularity of the elasto-plastic Hardening Soil (HS) model is based on simple parameter identification from standard testing and empirical formulas. The HS model is implemented in many commercial FE codes designed to analyse geotechnical problems. In its basic version, the stress–strain behaviour within the elastic range is subject to the hypoelastic power law, which assures the barotropy of the elastic stiffness. However,...
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Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides
PublikacjaQuercetin, one of the most abundant flavonoids in plant-based foods, commonly occurs in nature in various glycosylated forms. There is still a less explored aspect regarding the cause of its glycosides diversity, depending on the sugars moiety attached. This work focuses on four widespread quercetin glycosides—hyperoside, isoquercitrin, quercitrin and rutin—by testing property-tuning capacity of different sugar moieties and thus...
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Forecasting risks and challenges of digital innovations
PublikacjaForecasting and assessment of societal risks related to digital innovation systems and services is an urgent problem, because these solutions usually contain artificial intelligence algorithms which learn using data from the environment and modify their behaviour much beyond human control. Digital innovation solutions are increasingly deployed in transport, business and administrative domains, and therefore, if abused by a malicious...
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Potentiometric Solid-Contact Ion-Selective Electrode for Determination of Thiocyanate in Human Saliva
PublikacjaA new solid-contact potentiometric ion-selective electrode for the determination of SCN− (SCN-ISE) has been described. Synthesized phosphonium derivative of calix[4]arene was used as a charged ionophore. The research included selection of the ion-selective membrane composition, determination of the ISEs metrological parameters and SCN-ISE application for thiocyanate determination in human saliva. Preparation of the ISEs included...
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Ni-WC/Al2O3 and Ni-WC/MgWO4/MgAl2O4 catalysts for resource recovery via pyrolysis combined with the dry reforming of plastics (PCDR)
PublikacjaPlastic waste (PW) is currently one of an environmental threat. Despite the increasing share of recycled plastics, their disposal remains high. Therefore, there is a high demand for new PW management systems. Among them, pyrolysis combined with dry reforming (PCDR) is an advantageous solution because it allows for resource recovery in the form of gas and liquid fuels, with simultaneous utilization of CO2. To date, catalysts based...
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Medially positioned plate in first metatarsophalangeal joint arthrodesis
PublikacjaObjective The purpose of this study was to biomechanically compare the stability of first metatarsophalangeal (MTP1) joint arthrodesis with dorsally and medially positioned plates. Methods A physical model of the MTP1 joint consists of printed synthetic bones, a titanium locking plate and screws. In the experiments, samples with dorsally and medially positioned plates were subjected to loading of ground load character in a universal...
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Antibiotic Resistance of Uropathogens Isolated from Patients Hospitalized in District Hospital in Central Poland in 2020
PublikacjaThe aim of this study was to determine antibiotic resistance patterns and the prevalence of uropathogenes causing urinary tract infections (UTIs) in patients hospitalized in January–June 2020 in central Poland. Antimicrobial susceptibility testing was performed using the disk-diffusion method. Escherichia coli (52.2%), Klebsiella pneumoniae (13.7%), Enterococcus faecalis (9.3%), E. faecium (6.2%), and Proteus mirabilis (4,3%) were...
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Automatic Identification System (AIS) Dynamic Data Integrity Monitoring and Trajectory Tracking Based on the Simultaneous Localization and Mapping (SLAM) Process Model
PublikacjaTo enhance the safety of marine navigation, one needs to consider the involvement of the automatic identification system (AIS), an existing system designed for ship-to-ship and shipto- shore communication. Previous research on the quality of AIS parameters revealed problems that the system experiences with sensor data exchange. In coastal areas, littoral AIS does not meet the expectations of operational continuity and system availability,...
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Online Volatile Compound Emissions Analysis Using a Microchamber/Thermal Extractor Coupled to Proton Transfer Reaction-Mass Spectrometry
PublikacjaIndoor air is a complex and dynamic mixture comprising manifold volatile organic compounds (VOCs) that may cause physiological and/or psychological discomfort, depending on the nature of exposure. This technical note presents a novel approach to analyze VOC emissions by coupling a microchamber/thermal extractor (μ-CTE) system to a proton transfer reaction-mass spectrometer (PTR-MS). This configuration provides an alternative to...
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Is it possible to create a unified urban greenery management system (UGMS) on a national scale? The concept for EU Member State of Poland
PublikacjaMotives: Currently developed urban greenery management systems (UGMS) are limited in scope and profiled towards solving particular issues. Moreover, due to the lack of common standards and solutions, UGMS implementation requires considerable financial effort, which is only feasible for wealthy urban centres. There is a need for universal, cost-effective technological solutions which could constitute a common urban green infrastructure...
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Effect of small quantities of potassium promoter and steam on the catalytic properties of nickel catalysts in dry/combined methane reforming
PublikacjaCarbon dioxide and methane are two of the principal greenhouse gases. Reduction of their content in the atmosphere is currently the subject of much worldwide research. Dry and combined reforming of methane are effective methods of CO2 and CH4 utilization and production of synthesis gas (syngas) in chemical technology. Testing of catalysts that provide the desired H2/CO ratio and long operation time is one of the critical aspects...