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Wyniki wyszukiwania dla: human hair
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The dispersive micro-solid phase extraction method for MS-based lipidomics of human breast milk*
PublikacjaA simple and rapid microextraction method ensuring high lipidome coverage was developed for liquid chromatography mass spectrometry (LC-MS)-based lipidomics of human breast milk. The dispersive microsolid phase extraction (D-µ-SPE) technique, coupled with the design of experiment (DoE) method, enabled the study of the influence of several conditions (desorption solvent, stationary phase ratio, and sorption and desorption time)...
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Unsupervised machine-learning classification of electrophysiologically active electrodes during human cognitive task performance
PublikacjaIdentification of active electrodes that record task-relevant neurophysiological activity is needed for clinical and industrial applications as well as for investigating brain functions. We developed an unsupervised, fully automated approach to classify active electrodes showing event-related intracranial EEG (iEEG) responses from 115 patients performing a free recall verbal memory task. Our approach employed new interpretable...
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Multifactor consciousness level assessment of participants with acquired brain injuries employing human–computer interfaces
PublikacjaBackground A lack of communication with people suffering from acquired brain injuries may lead to drawing erroneous conclusions regarding the diagnosis or therapy of patients. Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the...
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Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems
PublikacjaSince human-associated bacteria have been recognized as vectors in two - way gene transmission between the pathogenic and environmental populations, health hazard connected with wastewater discharge requires reevaluation. In this paper the particular attention was given to antimicrobial-resistance of Escherichia coli and enterococci isolated from wastewater and wastewater impacted environments. The obtained results showed that...
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Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds
PublikacjaBackground Epidermal progenitor cells (EPCs) have been under extensive investigation due to their increasing potential of application in medicine and biotechnology. Cultured human EPCs are used in the treatment of chronic wounds and have recently became a target for gene therapy and toxicological studies. One of the challenges in EPCs culture is to provide a high number of undifferentiated, progenitor cells displaying high viability...
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Absorption spectroscopy setup for determination of whole human blood and blood–derived materials spectral characteristics
PublikacjaA dedicated absorption spectroscopy system was set up using tungsten-halogen broadband source, optical fibers, sample holder, and a commercial spectrometer with CCD array. Analysis of noise present in the setup was carried out. Data processing was applied to the absorption spectra to reduce spectral noise, and improve the quality of the spectra and to remove the baseline level. The absorption spectra were measured for whole blood...
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Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines
PublikacjaEpidemiological studies have shown that consumption of cab- bage and sauerkraut is connected with significant reduction of breast cancer incidences. Estrogens are considered a major breast cancer risk factor and their metabolism by P450 enzymes substan- tially contributes to carcinogenic activity. The aim of this study was to investigate the effect of cabbage and sauerkraut juices of differ- ent origin on the expression profile...
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Chemistry of human breast milk – a comprehensive review of the composition and role of milk metabolites in child development
PublikacjaEarly nutrition has an enormous influence on a child's physiological function, immune system maturation and cognitive development. Human breast milk (HBM) is recognized as the gold standard for human infant nutrition. Accordingly to WHO report breastfeeding is consider as an unequalled way of providing ideal food to the infant, which is required for his healthy growth and development. HBM contains various macronutrients (carbohydrates,...
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Podstawowe sposoby zwiększania wiarygodności wykonania przebiegów wymagających udziału człowieka w human workflow
PublikacjaOpisano pojęcie procesu biznesowego oraz przepływu pracy w kontekście automatyzacji mającej na celu optymalizację działań i podniesienie jakości usługi. Przedstawiono charakterystykę procesów pracy angażujących człowieka oraz wykorzystujących dedykowane wzorce przepływów tego typu. Zaproponowano zwiększenie stopnia automatyzacji wykonania procesu wraz z metodami zwiększania wiarygodności wykonania przebiegów pracy przez kontrolę...
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Long‐time scale simulations of virus‐like particles from three human‐norovirus strains
PublikacjaThe dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause gastroenteritis was investigated by means of long-time (about 30 μs in the laboratory timescale) molecular dynamics simulations with the coarse-grained UNRES force field. The main motion of VLP units turned out to be the bending at the junction between the P1 subdomain (that...
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Oxidative stress in humans: validation of biomarkers of DNA damage
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Evidence for consolidation of neuronal assemblies after seizures in humans
PublikacjaThe establishment of memories involves reactivation of waking neuronal activity patterns and strengthening of associated neural circuits during slow-wave sleep (SWS), a process known as "cellular consolidation" (Dudai and Morris, 2013). Reactivation of neural activity patterns during waking behaviors that occurs on a timescale of seconds to minutes is thought to constitute memory recall (O'Keefe and Nadel, 1978), whereas consolidation...
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A study to identify olfactory markers of fear in rats and humans
PublikacjaW pracy przedstawiono wyniki wstępnych badań ukierunkowanych na wykrycie podstawowych fermonów wydzielanych w sytuacji zagrożenia (fermony alarmowe) przez różne organizmy żywe.W badaniach zastosowano takie techniki jak TD-GC-MS, SPME-GC-MS stwierdzono występowanie fermonów należących do takich klas związków organicznych jak alkohole, węglowodory nasycone, aldehydy, kwasy karboksylowe i ketony.
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Olfactory and tissue markers of fear in mammals including humans
PublikacjaW pracy przedstawiono informacje na temat:-klasyfikacji i budowy chemicznej związków chemicznych zaliczanych do grupy feromonów,-ich rola w funkcjonowaniu organizmów żywych w tym także organizmu ludzkiego,wyników badań prowadzonych z wykorzystaniem komory ekspozycyjnej własnej konstrukcji,metodyk analitycznych wykorzystywanych do oznaczania śladowych zawartości feromonów w próbkach wydychanego powietrza.
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What defines excellent lighting design for humans and animals?
PublikacjaWhat defines excellent lighting design for humans and animals? The answer to the above question is more than complex. It is not enough nowadays to design a project to make it aesthetically pleasing. Nor is it sufficient to create nicely lit environments, or simply to achieve the light levels required by the lighting norms or standards. With the new scientific research of the last few decades that relates directly or indirectly...
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Development of different methods for drugs and psychoactive substances extraction from hair samples and their identification based on HPLC-ESI-QTOF analysis
PublikacjaOver the past decade, the use of non-controlled designer drugs and drug of abuse has rapidly increased. Hair, as a human matrix, enables detection of drugs incorporated into its structure. Studies of presence and identification of drug metabolites in human hair samples has been performed using liquid chromatography electrospray ionization quadrupole time of flight mass spectrometry (HPLC-ESI-QTOF-MS) with steady alternation of...
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The use of HPLC-Q-TOF-MS for comprehensive screening of drugs and psychoactive substances in hair samples and several “legal highs” products
PublikacjaNon-targeted screening of drugs present in herbal products, known as “legal high” drugs and in hair as a biological matrix commonly used in toxicological investigations was accomplished with the use of high pressure liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS). In total, 25 and 14 therapeutical drugs and psychoactive substances/metabolites were detected in investigated hair samples...
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Mercury emission to air, water and soil in Poland
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Changes in air tourism to Tunisia in 2009–2018
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Mobile monitoring system for gaseous air pollution
PublikacjaThe concept of a mobile monitoring system for chemical agents control in the air is presented. The proposed system can be applied to measure industrial and car traffic air pollution. A monitoring station is relatively small and can be placed on cars or public transportation vehicles. Measured concentrations of air pollutants are collected and transferred via the GSM network to a central data base. Exemplary results from a measurement...
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Mobile system for on-road measurements of air pollutants
PublikacjaW pracy zaprezentowano prototyp mobilnej stacji diagnostycznej do pomiarów stężeń typowych zanieczyszczeń powietrza (C6H6, NO2, NOx, CO i CO2) pochodzących z komunikacji w miastach. Nowością proponowanego systemu jest możliwość przeprowadzania pomiarów emisji zanieczyszczeń wzdłuż ciągów komunikacyjnych i w miejscach, w których nie mogą być zastosowane stacjonarne stacje monitoringowe. W proponowanym rozwiązaniu, urządzenie...
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Small photovoltaic setup for the air conditioning system
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Deep Eutectic Solvents and Their Uses for Air Purification
PublikacjaChemical compounds released into the air by the activities of industrial plants and emitted from many other sources, including in households (paints, waxes, cosmetics, disinfectants, plastic (PVC) flooring), may affect the environment and human health. Thus, air purification is an important issue in the context of caring for the condition of the environment. Deep eutectic solvents (DESs) as liquids with environmentally friendly...
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Microorganisms in the air over wastewater treatment plant.
PublikacjaCelem pracy było aktywności źródeł emisji mikroorganizmów do powietrza na terenie oczyszczalni ścieków. Stwierdzono iż najwyższe liczebności bakterii występowały w rejonie piaskowników i komór recyrkulacji osadu czynnego. Natomiast liczba bakterii w rejonie komór napowietrzania była zbliżona do tła.
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Passive samplers in indoor air quality control
PublikacjaPrzedstawiono wyniki badań jakości powietrza wewnętrznego w 12 wybranych mieszkaniach usytuowanych na terenie aglomeracji Trójmiejskiej z wykorzystaniem techniki pasywnej (dozymetria pasywna typu permeacyjnego) oraz techniki dynamicznej (rurki sorpcyjne wypełnione sorbentem Tenax TA). Wykorzystując nowe podejście do sposobu kalibracji dokonano monitoringu zarówno poszczególnych lotnych związków organicznych jak i sumarycznej zawartości...
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Review of the determination of pesticide residues in ambient air
PublikacjaW publikacji dokonano przeglądu najważniejszych metodyk oznaczania pozostałości pestycydów w powietrzu zewnętrznym. W publikacji przedstawiono także techniki używane do oznaczeń końcowych. Obecnie najpopularniejszą techniką oznaczeń końcowych jest chromatografia gazowa bądź cieczowa sprzężona ze spektrometrem mas.
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Wavelet analysis of frequency of air bubble departure
PublikacjaPrzedstawiono wyniki nieliniowej analizy częstotliwośći generowania pęcherzyków powietrza z dysz o średnicy 0.75 mm, 1.61 mm oraz 2.76 mm umieszczonych 15 cm poniżej poziomu wody.
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Air quality policy in the U.S. and the EU – a review
PublikacjaThe high level of atmospheric pollution is a global problem that has taken on particular significance in recent years and will continue to grow in the near future. Air pollution directly affects the health, living organisms, vegetation, water, soil and buildings. Additionally, it moves easily even over long distances. Certain air pollutants influence the climate, cause negative processes in the protective ozone layer and contribute...
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Current air quality analytics and monitoring: A review
PublikacjaThis review summarizes the different tools and concepts that are commonly applied in air quality monitoring. The monitoring of atmosphere is extremely important as the air quality is an important problem for large communities. Main requirements for analytical devices used for monitoring include a long period of autonomic operation and portability. These instruments, however, are often characterized by poor analytical performance....
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Environmental fate of BTEX compounds in ambient air
PublikacjaAs a result of the industrialization and urbanization in the world, human pressure on the environment is intensifying, leading to detrimental changes in both biotic and abiotic compartments. One of the many consequences of this state of affairs is the increasing rate of emission into the atmosphere of volatile organic compounds, including the so-called BTEX (benzene, ethylbenzene, toluene, xylenes) compounds. The article reviews...
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Air flow phenomena in the model of the blind drift
PublikacjaIn the presented paper, Particle Image Velocimetry (PIV) has been used to investigate flow pattern and turbulent structure in the model of blind drift. The presented model exist in mining, and has been analyzed to resolve ventilation issues. Blind region is particularly susceptible to unsafe methane accumulation. The measurement system allows us to evaluate all components of the velocity vector in channel cross-section simultaneously....
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Influence of the air phase on water flow in dikes
PublikacjaNumerical models are often used to describe flow and deformation processes occurring in dikes during flood events. Modeling of such phenomena is a challenging task, due to the complexity of the system, consisting of three material phases: soil skeleton, pore water and pore air. Additional difficulties are transient loading caused by variable in time water levels, heterogeneity of the soil or air...
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Instrumental techniques used in the analysis of exhaled air
PublikacjaExhaled air composition changes depending on the health status of the patient, making it possible to use breath analysis for diagnosis and monitoring purposes. Despite the fact that it is not yet used in every day medical practice, it potential application could facilitate the diagnostics of various diseases such as metabolic disorders, respiratory tract and gastrointestinal diseases. Described in this paper are different application...
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Electronic Noses for Indoor Air Quality Assessment
PublikacjaThis chapter presents a proposal of the use of electronic noses in the monitoring of indoor air quality. The main focus is put on the detailed characteristics of today’s indoor air quality control methods, the types of pollution in the air, and the development of electronic noses for air testing. Currently, scientists seek methodological and structural solutions that would enable real-time online indoor air control. It has been...
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Treatment of malodorous air in biotrickling filters: A review
PublikacjaOdour nuisance, resulting mainly from the presence of the compounds containing osmophore group and characterized by low olfactory threshold, is associated with danger and may be the cause of negative psychosomatic symptoms. Among different methods of malodorous air treatment, biological methods are of importance, mainly due to reduced operating costs, high purification efficiency of voluminous gas streams characterized by low concentrations...
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LY294002 and sorafenib as inhibitors of intracellular survival pathways in the elimination of human glioma cells by programmed cell death
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Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
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Changes in the Thickness of Ice Cover on Water Bodies Subject to Human Pressure (Silesian Upland, Southern Poland)
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IL-33 and IL-4 impair barrier functions of human vascular endothelium via different mechanisms
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The effect of interleukin-35 on the integrity, ICAM-1 expression and apoptosis of human aortic smooth muscle cells
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Immunoscore, circulating tumor cells and human-derived organoids as potential predictive tools in personalized cancer medicine
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Interactions of Nitroaromatic Compounds with the Mammalian Selenoprotein Thioredoxin Reductase and the Relation to Induction of Apoptosis in Human Cancer Cells
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Inhibition of phthalocyanine-sensitized photohemolysis of human erythrocytes by polyphenolic antioxidants: description of quantitative structure–activity relationships
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Erratum to: Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
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Sequential induction of mitotic catastrophe followed by apoptosis in human leukemia MOLT4 cells by imidazoacridinone C-1311
PublikacjaWykazano, że pochodna imidazoakrydonu C-1311 indukuje zahamowanie progresji komórek MOLT4 w fazie G2M cyklu życiowego. Podwyższona ekspresja fosfoepitopu MPM-2 przy jednoczesnym zaniku ufosforylowanej formy Tyr15-cdc2 wskazywała, iż komórki początkowo zablokowane w fazie G2 przechodziły do mitozy. Jednocześnie na skutek nieprawidłowego przebiegu mitozy komórki ulegały katastrofie mitotycznej. Analiza biochenicznych markerów apoptozy...
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The response of human colon cancer cells to C-1748 (4-methyl-1-nitroacridine derivative) treatment
PublikacjaPrzeprowadzone badania miały na celu określenie wpływu pochodnej 4-metylo-1-nitroakrydyny C-1748 na komórki ludzkiego raka okrężnicy HCT8 oraz HT29. Komórki obu linii, traktowane badanym związkiem, ulegały przede wszystkim apoptozie, przy czym liczba komórek apoptotycznych była znacznie większa w przypadku linii HCT8. Ponadto, proliferacja części komórek HCT8, została zahamowana w wyniku uruchomienia procesu starzenia, czego nie...
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A new methodological approach to the noise threat evaluation based on the selected physiological properties of the human hearing system
PublikacjaA new way of assessment of noise-induced harmful effects on human hearing system is presented in the paper. The method takes into consideration properties of the selected physiological human hearing system. On the basis of the hearing examinations and noise measurements results and psychoacoustical noise dosimeter performance the new indicators of the noise harmfulness were proposed. The evaluation of the proposed indicators were...
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A FEM membrane model of human fascia-synthetic implant system in a case of a stiff ventral hernia orifice
PublikacjaPraca prezdstawia model matematyczny układu tkanka ludzka - implant syntetyczny w postaci tzw. siatki w leczeniu przepuklin brzusznych. Implant jest tu moelowany jako struktura membranowa. Ocena wpływu danych materiałowych oraz wstępnego napięcia na zachowanie pracującej membrany po implantacji została przedstawiona na podstawie analizy wrażliwości. Pracę podsumowują pewne wskazówki dla chirurgów implantujących siatki.
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A Simple Model of Linkage Disequilibrium and Genetic Drift in Human Genomic SNPs: Importance of Demography and SNP Age
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Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C
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